CN107595722B - Hawthorn beauty skin cream, preparation method and application thereof - Google Patents

Hawthorn beauty skin cream, preparation method and application thereof Download PDF

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CN107595722B
CN107595722B CN201711082269.9A CN201711082269A CN107595722B CN 107595722 B CN107595722 B CN 107595722B CN 201711082269 A CN201711082269 A CN 201711082269A CN 107595722 B CN107595722 B CN 107595722B
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hawthorn
cream
fruit extract
liposome
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CN107595722A (en
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巴卫松
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Hebei Quanmei Biotechnology Co ltd
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Hebei Quanmei Biotechnology Co ltd
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Abstract

The invention provides a hawthorn beauty skin cream, a preparation method and application thereof, and relates to the technical field of cosmetics. The hawthorn fruit extract is rich in various substances such as procyanidine, plant organic acid, tannin and the like, has the effects of resisting skin aging, removing acne, whitening, brightening and the like, and can achieve the effects of clearing free radicals of human skin, whitening and firming skin and reducing pores. However, because procyanidin has strong hydrophilicity, and epicatechin oligomers in procyanidin are easily oxidized in water and lose efficacy, the preparation method of the skin care product after coating the hawthorn fruit extract into a stable lipid coating body well overcomes the defects. The hawthorn beauty skin cream is rich in procyanidine with super strong free radical resisting activity, and has good effect of resisting free radical damage when being applied as day cream.

Description

Hawthorn beauty skin cream, preparation method and application thereof
Technical Field
The invention relates to the technical field of cosmetics, in particular to a hawthorn beauty skin cream, a preparation method and application thereof.
Background
The skin cells of human beings in a natural state are renewed every 28 days, and belong to tissues with fast metabolism. Facial skin aging is closely associated with free radical damage. When the human body is irradiated by ionizing radiation and ultraviolet rays, a large amount of free radicals are generated, and if the free radicals in blood and tissues cannot be effectively eliminated in time, the super oxidation of the free radicals attacks new skin cells and mature cells all the time, and finally, the updated cells and mature cells are subjected to premature aging apoptosis and even canceration!
The existing research shows that the hawthorn is rich in various substances such as procyanidine, plant organic acid, tannin and the like, wherein the components such as anthocyanin and the like have strong antioxidant activity, can effectively remove free radicals of skin cells of a human body, and relieve the senescence and apoptosis of the skin cells.
Therefore, it is necessary and urgent to fully utilize the beauty and skin care effects of hawthorns, research and develop a hawthorn beauty and skin care cream which has the effects of resisting skin aging, removing acne, whitening, brightening and the like, and can achieve the effects of well clearing free radicals of human skin, whitening, firming skin and shrinking pores.
In view of the above, the present invention is particularly proposed.
Disclosure of Invention
The invention aims to provide a hawthorn beautifying skin cream which is prepared by adding an extract of hawthorn fruits coated by liposome into a cream matrix, has the effects of resisting skin aging, removing acne, whitening, brightening and the like, and can achieve the effects of well clearing free radicals of human skin, whitening and firming skin and reducing pores.
The second purpose of the invention is to provide a preparation method of the hawthorn beauty skin cream, which has simple preparation process, does not need complex preparation equipment, is environment-friendly and has no pollution to the environment in the preparation process.
The third purpose of the invention is to provide application of the hawthorn beauty skin cream as day cream.
The invention provides a hawthorn beauty skin cream which is prepared by adding an extract of hawthorn fruits coated by liposome into a cream matrix.
Furthermore, the content of procyanidine in the hawthorn fruit extract is 90-95 wt%, and the content of plant organic total acid is 1-1.5 wt%.
Further, the liposome is submicron liposome.
Further, the skin cream also comprises salicylic acid.
Preferably, the salicylic acid accounts for 1-3% of the total mass of the hawthorn beauty skin cream.
Further, the cream base is an O/W type emulsion, and comprises an oil phase base and a water phase base, wherein:
the oil phase matrix mainly comprises, by weight, 20-30 parts of white vaseline, 8-12 parts of octadecanol, 2-6 parts of glyceryl monostearate, 1-5 parts of sodium dodecyl sulfate, 4-8 parts of shea butter and 202-6 parts of ceteareth-202;
the water-phase matrix mainly comprises 12-16 parts by weight of glycerin, 0.2-1 part by weight of ethyl p-hydroxybenzoate and 180-22 parts by weight of distilled water.
Further, the oil phase matrix also comprises essence.
Preferably, the essence is rose essential oil.
The invention provides a preparation method of hawthorn beauty skin cream, which comprises the following steps:
(a) preparing a cream base: respectively mixing an oil phase matrix and a water phase matrix uniformly, heating to 70-80 ℃, preserving heat for 15-25 minutes, and then slowly adding the oil phase matrix into the water phase matrix, wherein the mass ratio of the oil phase matrix to the water phase matrix is 1: 3-5, stirring while adding to form a cream matrix;
(b) and (3) liposome coating: grinding the hawthorn fruit extract, sieving the ground hawthorn fruit extract by a sieve of 100-150 meshes, and then coating the hawthorn fruit extract by using liposome to prepare the hawthorn fruit extract coated by the liposome;
(c) uniformly mixing and preparing: and (c) adding salicylic acid and the hawthorn fruit extract coated by the liposome prepared in the step (b) into the cream matrix prepared in the step (a), and fully and uniformly stirring to prepare the hawthorn beauty skin cream.
Furthermore, the coating rate of the hawthorn fruit extract in the step (b) coated by the liposome is 3-5%.
Further, the content of the hawthorn fruit extract coated by the liposome in the hawthorn beautifying skin cream prepared in the step (c) is 5-15 wt%.
The invention provides application of hawthorn beauty skin cream in daily cream.
Compared with the prior art, the invention has the beneficial effects that:
the invention provides a hawthorn beauty skin cream which is prepared by adding an extract of hawthorn fruits coated by liposome into a cream matrix. The hawthorn fruit extract is rich in various substances such as procyanidine, plant organic acid, tannin and the like, has the effects of resisting skin aging, removing acne, whitening, brightening and the like, and can achieve the effects of clearing free radicals of human skin, whitening and firming skin and reducing pores. However, procyanidins have strong hydrophilicity, and epicatechin oligomers in procyanidins are easily oxidized in water and thus are ineffective. Therefore, the skin care product must be prepared after being wrapped into a stable lipid coating.
According to the preparation method of the hawthorn beauty skin cream, provided by the invention, the cream matrix and the lipid coating body are respectively prepared, and then the salicylic acid and the lipid coating body are added into the cream matrix and uniformly mixed to prepare the hawthorn beauty skin cream.
According to the application of the hawthorn beauty skin cream provided by the invention, as the damage of free radicals on human skin in daytime is greatly higher than that of human skin at night, the beauty skin cream rich in procyanidine with super-strong anti-free radical activity is applied as day cream.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
According to one aspect of the invention, the hawthorn beauty skin cream is mainly prepared by adding an extract of hawthorn fruits coated by liposome into a cream matrix.
In the invention, the hawthorn fruit extract is rich in various substances such as procyanidine, plant organic acid, tannin and the like, wherein:
procyanidine in fructus crataegi extract has multiple phenolic hydroxyl groups, has super strong reducibility, and can exert strong free radical scavenging effect after entering skin tissue and blood vessel, thereby protecting new skin cell and mature cell, and improving human facial cell state to a certain extent. In addition, according to research, it is found that acne and alopecia are closely related to a biological enzyme generated by excessive secretion of male hormones in human beings, which is usually present in the root of hair follicle, and causes the pores to be excessively opened to cause external bacterial invasion to form folliculitis, and normal passage to be closed, and finally causes the generation of pox and the failure of normal growth (which grows out but dies soon). Epicatechin dimer in fructus crataegi procyanidine has the effects of inhibiting and weakening the expression of biological enzyme, and can be used for treating acne and alopecia;
the tannin in the hawthorn fruit extract can generate good convergence on skin, and can resist the invasion of external environment microorganisms by tightening the skin and shrinking pores;
the organic acids such as fruit acid, citric acid and the like contained in the hawthorn fruit extract have small molecular weight, can permeate into the root of hair follicle, inhibit and kill anaerobic bacteria, and also can play a certain role in treating folliculitis;
meanwhile, the procyanidine in the hawthorn fruit extract has a plurality of phenolic hydroxyl groups in the molecular structure and large polarity, so that the hawthorn fruit extract has strong hydrophilicity, and epicatechin oligomers and polymers are stored in the hawthorn fruit extract, so that the molecular weight difference is large, the oligomers are easily oxidized and are particularly oxidized in an aqueous medium to lose effectiveness. Therefore, the skin care product is prepared after the skin care product is coated with the stable liposome-coated hawthorn fruit extract.
Therefore, the hawthorn beauty skin cream is mainly prepared by adding the hawthorn fruit extract coated by the liposome into a cream matrix. The hawthorn fruit extract is rich in various substances such as procyanidine, plant organic acid, tannin and the like, has the effects of resisting skin aging, removing acne, whitening, brightening and the like, and can achieve the effects of clearing free radicals of human skin, whitening and firming skin and reducing pores. However, procyanidins have strong hydrophilicity, and epicatechin oligomers in procyanidins are easily oxidized in water and thus are ineffective. Therefore, the skin care product must be prepared after being wrapped into a stable lipid coating.
In a preferred embodiment of the present invention, the content of procyanidins in the hawthorn fruit extract is 90 to 95wt%, and the content of total organic acids in the plant is 1 to 1.5 wt%.
As a preferred embodiment, the content of procyanidine in the hawthorn fruit extract is 90-95 wt%, so that the prepared skin cream has stronger anti-free radical activity; the content of the plant organic total acid is 1-1.5 wt%, and the better effect of inhibiting and killing anaerobic bacteria can be achieved.
According to the invention, researches show that when the content of procyanidine in the hawthorn extract is lower than 90%, the content of organic acid is higher, the pH value is less than or equal to 4, the polarity is very high, and the lipid is extremely difficult to wrap the extract, even cannot wrap the extract. With the increase of the content, the wrapping rate gradually increases. When the content is higher than 95%, the pH value of the extract is more than or equal to 6, and if the purity of the procyanidin is continuously improved, the acidic environment created by the organic acid is gradually lost, so that the procyanidin is rapidly denatured and ineffective, the organic acid can inhibit and kill bacteria, epidermal cells aged by skin are removed, and the effect of cleaning the skin is poor.
In a preferred embodiment of the invention, the liposomes are submicron liposomes.
In a preferred embodiment, the liposome is a submicron liposome, and the stability of the procyanidine in the beauty skin cream can be greatly improved after the submicron liposome is used for stably wrapping the hawthorn fruit extract.
In a preferred embodiment of the present invention, the skin cream further comprises salicylic acid.
Preferably, the salicylic acid accounts for 1-3% of the total mass of the hawthorn beauty skin cream.
As a preferable embodiment, the salicylic acid has weak corrosivity to skin, accounts for 1-3% of the total mass of the hawthorn beauty skin cream, and can effectively remove aged and apoptotic epidermal cells.
In a preferred embodiment of the present invention, the cream base is an O/W type emulsion comprising an oil phase base and an aqueous phase base, wherein:
the oil phase matrix mainly comprises, by weight, 20-30 parts of white vaseline, 8-12 parts of octadecanol, 2-6 parts of glyceryl monostearate, 1-5 parts of sodium dodecyl sulfate, 4-8 parts of shea butter and 202-6 parts of ceteareth-202;
the water-phase matrix mainly comprises 12-16 parts by weight of glycerin, 0.2-1 part by weight of ethyl p-hydroxybenzoate and 180-22 parts by weight of distilled water.
In a preferred embodiment, the cream base is an O/W emulsion, which is more easily absorbed by human skin.
In the above preferred embodiment, the oil phase base further comprises a perfume.
Preferably, the essence is rose essential oil.
As a preferred embodiment, essence is added into the oil phase matrix to mask the unpleasant taste of the extract.
According to one aspect of the invention, the preparation method of the hawthorn beauty skin cream comprises the following steps:
(a) preparing a cream base: respectively mixing an oil phase matrix and a water phase matrix uniformly, heating to 70-80 ℃, preserving heat for 15-25 minutes, and then slowly adding the oil phase matrix into the water phase matrix, wherein the mass ratio of the oil phase matrix to the water phase matrix is 1: 3-5, stirring while adding to form a cream matrix;
(b) and (3) liposome coating: grinding the hawthorn fruit extract, sieving the ground hawthorn fruit extract by a sieve of 100-150 meshes, and then coating the hawthorn fruit extract by using liposome to prepare the hawthorn fruit extract coated by the liposome;
(c) uniformly mixing and preparing: and (c) adding salicylic acid and the hawthorn fruit extract coated by the liposome prepared in the step (b) into the cream matrix prepared in the step (a), and fully and uniformly stirring to prepare the hawthorn beauty skin cream.
According to the preparation method of the hawthorn beauty skin cream, the cream matrix and the lipid coating body are respectively prepared, and then the salicylic acid and the lipid coating body are added into the cream matrix and uniformly mixed to prepare the hawthorn beauty skin cream.
In a preferred embodiment of the present invention, the coating rate of the haw apple extract in step (b) with liposome is 3-5%.
As a preferred embodiment, it has been found that procyanidins extracted from other plants such as grape seeds have a high epicatechin multimer (5 polymers or more) content, i.e., a high average degree of polymerization and a high molecular weight, and thus it is difficult for liposomes to encapsulate them, and the encapsulation rate is low, usually 2% or less, and the cream procyanidins obtained do not reach a certain effective amount and hardly exert their effects. The epicatechin oligomer (less than 4 polymers) in the procyanidine extracted from the hawthorn has high content, small molecular weight and small volume, and can effectively improve the coating rate of the liposome to 3-5%.
In a preferred embodiment of the present invention, the content of the liposome-coated hawthorn fruit extract in the hawthorn cosmetic skin cream prepared in step (c) is 5 to 15 wt%.
As a preferred embodiment, the content of the liposome-coated hawthorn fruit extract in the hawthorn beauty skin cream is 5-15 wt%, so that the hawthorn beauty skin cream has better effects of resisting skin aging, removing acne, whitening, brightening and the like.
Preferably, the content of the hawthorn fruit extract coated by the liposome in the hawthorn beautifying skin cream is 10 wt%.
According to one aspect of the invention, the hawthorn beauty skin cream is used as day cream.
In the invention, because the free radical damage of human skin in daytime is greatly more than that in night, the beauty skin cream rich in procyanidine with super-strong anti-free radical activity is applied as day cream.
The technical solution of the present invention will be further described with reference to examples and comparative examples.
Example 1
A cream base comprising an oil phase base and an aqueous phase base, wherein:
the oil phase matrix mainly comprises 20 parts by weight of white vaseline, 8 parts by weight of octadecanol, 2 parts by weight of glyceryl monostearate, 1 part by weight of sodium dodecyl sulfate, 4 parts by weight of shea butter and 202 parts by weight of cetostearyl polyether;
the water-phase matrix mainly comprises 12 parts by weight of glycerin, 0.2 part by weight of ethyl p-hydroxybenzoate and 180 parts by weight of distilled water;
the preparation method of the cream matrix comprises the following steps: respectively mixing the oil phase matrix and the water phase matrix uniformly, heating to 70 ℃, preserving heat for 15 minutes, and then slowly adding the oil phase matrix into the water phase matrix, wherein the mass ratio of the oil phase matrix to the water phase matrix is 1: 3, stirring while adding to prepare the cream base.
Example 2
A cream base comprising an oil phase base and an aqueous phase base, wherein:
the oil phase matrix mainly comprises 30 parts of white vaseline, 12 parts of octadecanol, 6 parts of glyceryl monostearate, 5 parts of sodium dodecyl sulfate, 8 parts of shea butter and 206 parts of cetostearyl polyether by weight;
the water-phase matrix mainly comprises 16 parts by weight of glycerol, 1 part by weight of ethyl p-hydroxybenzoate and 220 parts by weight of distilled water;
the preparation method of the cream matrix comprises the following steps: respectively mixing the oil phase matrix and the water phase matrix uniformly, heating to 80 ℃, preserving heat for 25 minutes, and then slowly adding the oil phase matrix into the water phase matrix, wherein the mass ratio of the oil phase matrix to the water phase matrix is 1: and 5, stirring while adding to prepare the cream base.
Example 3
A cream base comprising an oil phase base and an aqueous phase base, wherein:
the oil phase matrix mainly comprises 22 parts by weight of white vaseline, 9 parts by weight of octadecanol, 3 parts by weight of glyceryl monostearate, 2 parts by weight of sodium dodecyl sulfate, 5 parts by weight of shea butter and 203 parts by weight of ceteareth;
the water-phase matrix mainly comprises 14 parts by weight of glycerol, 0.4 part by weight of ethyl p-hydroxybenzoate and 190 parts by weight of distilled water;
the preparation method of the cream matrix comprises the following steps: respectively mixing the oil phase matrix and the water phase matrix uniformly, heating to 72 ℃, preserving heat for 18 minutes, and then slowly adding the oil phase matrix into the water phase matrix, wherein the mass ratio of the oil phase matrix to the water phase matrix is 1: 3, stirring while adding to prepare the cream base.
Example 4
A cream base comprising an oil phase base and an aqueous phase base, wherein:
the oil phase matrix mainly comprises 28 parts by weight of white vaseline, 11 parts by weight of octadecanol, 5 parts by weight of glyceryl monostearate, 4 parts by weight of sodium dodecyl sulfate, 7 parts by weight of shea butter and 205 parts by weight of ceteareth;
the water-phase matrix mainly comprises 15 parts by weight of glycerin, 0.8 part by weight of ethyl p-hydroxybenzoate and 210 parts by weight of distilled water;
the preparation method of the cream matrix comprises the following steps: respectively mixing the oil phase matrix and the water phase matrix uniformly, heating to 78 ℃, preserving heat for 22 minutes, and then slowly adding the oil phase matrix into the water phase matrix, wherein the mass ratio of the oil phase matrix to the water phase matrix is 1: and 5, stirring while adding to prepare the cream base.
Example 5
A cream base comprising an oil phase base and an aqueous phase base, wherein:
the oil phase matrix mainly comprises 25 parts by weight of white vaseline, 10 parts by weight of octadecanol, 4 parts by weight of glyceryl monostearate, 3 parts by weight of sodium dodecyl sulfate, 5 parts by weight of shea butter and 204 parts by weight of ceteareth-204;
the water-phase matrix mainly comprises 14 parts by weight of glycerol, 0.5 part by weight of ethyl p-hydroxybenzoate and 200 parts by weight of distilled water;
the preparation method of the cream matrix comprises the following steps: respectively mixing the oil phase matrix and the water phase matrix uniformly, heating to 70 ℃, preserving heat for 20 minutes, and then slowly adding the oil phase matrix into the water phase matrix, wherein the mass ratio of the oil phase matrix to the water phase matrix is 1: 4, stirring while adding to prepare the cream base.
Example 6
A preparation method of hawthorn beauty skin cream comprises the following steps:
(a) and (3) liposome coating: grinding the hawthorn fruit extract, sieving the ground hawthorn fruit extract by a 100-mesh sieve, and then coating the hawthorn fruit extract by using submicron liposome to prepare the hawthorn fruit extract coated by the liposome;
the content of procyanidine in the hawthorn fruit extract is 90 wt%, and the content of plant organic total acid is 1 wt%.
(b) Uniformly mixing and preparing: adding salicylic acid and the hawthorn fruit extract coated by the liposome into the cream matrix prepared in the example 1, and fully and uniformly stirring to prepare the hawthorn beauty skin cream;
wherein, the hawthorn beauty skin cream comprises 94 percent of cream matrix, 5 percent of hawthorn fruit extract coated by liposome and 1 percent of salicylic acid according to weight percentage.
Example 7
A preparation method of hawthorn beauty skin cream comprises the following steps:
(a) and (3) liposome coating: grinding the hawthorn fruit extract, sieving the ground hawthorn fruit extract by a 150-mesh sieve, and then coating the hawthorn fruit extract by using submicron liposome to prepare the hawthorn fruit extract coated by the liposome;
the content of procyanidine in the hawthorn fruit extract is 95wt%, and the content of plant organic total acid is 1.5 wt%.
(b) Uniformly mixing and preparing: adding salicylic acid and the hawthorn fruit extract coated by the liposome into the cream matrix prepared in the embodiment 2, and fully and uniformly stirring to prepare the hawthorn beauty skin cream;
wherein, the hawthorn beauty skin cream comprises 82 percent of cream matrix, 15 percent of hawthorn fruit extract coated by liposome and 3 percent of salicylic acid according to weight percentage.
Example 8
A preparation method of hawthorn beauty skin cream comprises the following steps:
(a) and (3) liposome coating: grinding the hawthorn fruit extract, sieving the ground hawthorn fruit extract by a 140-mesh sieve, and then coating the hawthorn fruit extract by using submicron liposome to prepare the hawthorn fruit extract coated by the liposome;
the content of procyanidine in the hawthorn fruit extract is 94 wt%, and the content of plant organic total acid is 1.4 wt%.
(b) Uniformly mixing and preparing: adding salicylic acid and the hawthorn fruit extract coated by the liposome into the cream matrix prepared in the embodiment 3, and fully and uniformly stirring to prepare the hawthorn beauty skin cream;
the hawthorn beauty skin cream comprises, by weight, a cream matrix, 12% of hawthorn fruit extract coated by liposome and 3% of salicylic acid.
Example 9
A preparation method of hawthorn beauty skin cream comprises the following steps:
(a) and (3) liposome coating: grinding the hawthorn fruit extract, sieving with a 120-mesh sieve, and then coating the hawthorn fruit extract with submicron liposome to obtain the hawthorn fruit extract coated with liposome;
the content of procyanidine in the hawthorn fruit extract is 92 wt%, and the content of plant organic total acid is 1.2 wt%.
(b) Uniformly mixing and preparing: adding salicylic acid and the hawthorn fruit extract coated by the liposome into the cream matrix prepared in the embodiment 4, and fully and uniformly stirring to prepare the hawthorn beauty skin cream;
wherein, the hawthorn beauty skin cream comprises 91 percent of cream matrix, 8 percent of hawthorn fruit extract coated by liposome and 1 percent of salicylic acid according to weight percentage.
Example 10
A preparation method of hawthorn beauty skin cream comprises the following steps:
(a) and (3) liposome coating: grinding the hawthorn fruit extract, sieving the ground hawthorn fruit extract by a 130-mesh sieve, and then coating the hawthorn fruit extract by using submicron liposome to prepare the hawthorn fruit extract coated by the liposome;
the content of procyanidine in the hawthorn fruit extract is 93 wt%, and the content of plant organic total acid is 1.3 wt%.
(b) Uniformly mixing and preparing: adding salicylic acid and the hawthorn fruit extract coated by the liposome into the cream matrix prepared in the example 5, and fully and uniformly stirring to prepare the hawthorn beauty skin cream;
wherein, the hawthorn beauty skin cream comprises 88 percent of cream matrix, 10 percent of hawthorn fruit extract coated by liposome and 2 percent of salicylic acid according to weight percentage.
Comparative example 1
This example is the same as example 10 except that in step (a), the content of procyanidins in the hawthorn fruit extract is 85 wt%, and the content of total plant organic acids is 3 wt%.
Comparative example 2
This example is the same as example 10 except that in step (b), the hawthorn beauty skin cream comprises, by weight, 78% of cream base, 20% of liposome-coated hawthorn fruit extract, and 2% of salicylic acid.
Effect example 1
80 patients with facial skin dullness and skin pore enlargement causing dermatitis due to long-term radiation facing a computer screen are selected, wherein 40 males and 40 females randomly divide volunteers into 4 groups, wherein 10 females and 10 males in each group,
a first group of volunteers were each asked to apply the hawthorn beauty skin cream prepared in example 10 of the present invention every morning; a second group of volunteers applied the hawthorn beauty skin cream prepared in comparative example 1 of the present invention every morning; a third group of volunteers applied the hawthorn beauty skin cream prepared in comparative example 2 of the present invention every morning; a fourth group of volunteers was applied daily in the early morning using a commercially available bactroban cream.
Then, each group of volunteers were revisited at intervals, and the recovery conditions of dermatitis of each group of volunteers were classified and recorded according to no obvious change, all improvement, obvious improvement and recovery, and the statistical results are shown in the following table:
Figure GDA0002816799850000131
Figure GDA0002816799850000141
according to the above table, the cure rate of the hawthorn beauty skin cream prepared in the example 10 of the present application to the patients who face the computer screen for a long time and radiate, so that the facial skin is dim, the skin pore is enlarged, and the dermatitis is caused is obviously higher than that of the hawthorn beauty skin cream prepared in the comparative examples 1 and 2 and the commercial Baidobang cream
Compared with the effect of the hawthorn beauty skin cream prepared in the comparative example 1, the treatment effect of the hawthorn beauty skin cream prepared in the comparative example 1 is obviously lower than that of the hawthorn beauty skin cream prepared in the example 10 of the application. Experiments show that when the content of the procyanidine in the hawthorn extract in the comparative example 1 is 85%, the content of the organic acid is higher, the pH value is 3.6, the polarity is very high, the liposome is extremely difficult to wrap, the wrapping rate of the liposome is only about 2% by measurement, and the procyanidine in the hawthorn beauty cream cannot reach a certain effective amount and cannot play a role.
In conclusion, the hawthorn beauty skin cream is prepared by adding the hawthorn fruit extract coated by the liposome into a cream matrix. The hawthorn fruit extract is rich in various substances such as procyanidine, plant organic acid, tannin and the like, has the effects of resisting skin aging, removing acne, whitening, brightening and the like, and can achieve the effects of clearing free radicals of human skin, whitening and firming skin and reducing pores. However, procyanidins have strong hydrophilicity, and epicatechin oligomers in procyanidins are easily oxidized in water and thus are ineffective. The invention coats the hawthorn fruit extract into a stable lipid coating body and then prepares the skin care product, thereby well overcoming the defects.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims (5)

1. The preparation method of the hawthorn beauty skin cream is characterized by comprising the following steps:
(a) preparing a cream base: respectively mixing an oil phase matrix and a water phase matrix uniformly, heating to 70-80 ℃, preserving heat for 15-25 minutes, and then slowly adding the oil phase matrix into the water phase matrix, wherein the mass ratio of the oil phase matrix to the water phase matrix is 1: 3-5, stirring while adding to form a cream matrix;
(b) and (3) liposome coating: grinding the hawthorn fruit extract, sieving the ground hawthorn fruit extract by a sieve of 100-150 meshes, and then coating the hawthorn fruit extract by using liposome to prepare the hawthorn fruit extract coated by the liposome;
(c) uniformly mixing and preparing: adding salicylic acid and the hawthorn fruit extract coated by the liposome prepared in the step (b) into the cream matrix prepared in the step (a), and fully and uniformly stirring to prepare the hawthorn beauty skin cream;
the content of the hawthorn fruit extract coated by the liposome in the hawthorn beautifying skin cream prepared in the step (c) is 5-15 wt%;
the content of procyanidine in the hawthorn fruit extract is 90-95 wt%, and the content of plant organic total acid is 1-1.5 wt%; the coating rate of the hawthorn fruit extract coated by the liposome is 3-5%.
2. The method for preparing the hawthorn beauty skin cream as claimed in claim 1, wherein the liposome is submicron liposome.
3. The preparation method of the hawthorn beauty skin cream as claimed in claim 1, wherein the salicylic acid accounts for 1-3% of the total mass of the hawthorn beauty skin cream.
4. The preparation method of the hawthorn beauty skin cream as claimed in claim 1, wherein the cream base is an O/W type emulsion, and comprises an oil phase base and a water phase base, wherein:
the oil phase matrix mainly comprises, by weight, 20-30 parts of white vaseline, 8-12 parts of octadecanol, 2-6 parts of glyceryl monostearate, 1-5 parts of sodium dodecyl sulfate, 4-8 parts of shea butter and 202-6 parts of ceteareth-202;
the water-phase matrix mainly comprises 12-16 parts by weight of glycerin, 0.2-1 part by weight of ethyl p-hydroxybenzoate and 180-220 parts by weight of distilled water.
5. The preparation method of the hawthorn beauty skin cream as claimed in claim 4, wherein the oil phase matrix further comprises essence, and the essence is rose essential oil.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049354A (en) * 2006-05-15 2007-10-10 吉林大学 Method for extracting effective constituent in raw material of hawthorn
CN106109312A (en) * 2016-07-18 2016-11-16 郑州景鸿畜牧科技有限公司 Fructus Crataegi pearly-lustre bath foam

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049354A (en) * 2006-05-15 2007-10-10 吉林大学 Method for extracting effective constituent in raw material of hawthorn
CN106109312A (en) * 2016-07-18 2016-11-16 郑州景鸿畜牧科技有限公司 Fructus Crataegi pearly-lustre bath foam

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
安麓山楂润肤乳;巴颜喀拉化妆品贸易(上海)有限公司;《国产非特殊用途化妆品备案,http://125.35.6.80:8181/ftban/itownet/hzp_ba/fw/pz.jsp?processid=20160120173825hknfy&nid=20160120173825hknfy》;20160202;第1页"成分" *
山楂原花青素的抗氧化活性研究;金宁;《食品与发酵工业》;20070131;第45-47页 *

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