CN107550611B - Vascular stent - Google Patents
Vascular stent Download PDFInfo
- Publication number
- CN107550611B CN107550611B CN201710970707.9A CN201710970707A CN107550611B CN 107550611 B CN107550611 B CN 107550611B CN 201710970707 A CN201710970707 A CN 201710970707A CN 107550611 B CN107550611 B CN 107550611B
- Authority
- CN
- China
- Prior art keywords
- repeating
- repeating unit
- repeating units
- arc
- support body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000002792 vascular Effects 0.000 title claims abstract description 42
- 230000008093 supporting effect Effects 0.000 claims abstract description 9
- 239000000178 monomer Substances 0.000 claims description 42
- 230000007704 transition Effects 0.000 claims description 20
- 238000005452 bending Methods 0.000 claims description 15
- 210000004351 coronary vessel Anatomy 0.000 abstract description 11
- 210000004204 blood vessel Anatomy 0.000 description 7
- 229910052751 metal Inorganic materials 0.000 description 6
- 239000002184 metal Substances 0.000 description 6
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- 229920002988 biodegradable polymer Polymers 0.000 description 4
- 239000004621 biodegradable polymer Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- WAIPAZQMEIHHTJ-UHFFFAOYSA-N [Cr].[Co] Chemical class [Cr].[Co] WAIPAZQMEIHHTJ-UHFFFAOYSA-N 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000010147 laser engraving Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 229910000861 Mg alloy Inorganic materials 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 229910045601 alloy Inorganic materials 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 208000037803 restenosis Diseases 0.000 description 2
- 229910001285 shape-memory alloy Inorganic materials 0.000 description 2
- GQLCSJBRVSWWDV-UHFFFAOYSA-N 2-hydroxyacetic acid oxepan-2-one Chemical compound OCC(O)=O.O=C1CCCCCO1 GQLCSJBRVSWWDV-UHFFFAOYSA-N 0.000 description 1
- VSKXVGWORBZZDY-UHFFFAOYSA-N 2-hydroxypropanoic acid;oxepan-2-one Chemical compound CC(O)C(O)=O.O=C1CCCCCO1 VSKXVGWORBZZDY-UHFFFAOYSA-N 0.000 description 1
- 229910018131 Al-Mn Inorganic materials 0.000 description 1
- 229910018461 Al—Mn Inorganic materials 0.000 description 1
- 206010003211 Arteriosclerosis coronary artery Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 201000000057 Coronary Stenosis Diseases 0.000 description 1
- 206010011089 Coronary artery stenosis Diseases 0.000 description 1
- 229910000640 Fe alloy Inorganic materials 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 229920000954 Polyglycolide Polymers 0.000 description 1
- 229910001362 Ta alloys Inorganic materials 0.000 description 1
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- 206010057469 Vascular stenosis Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 208000026758 coronary atherosclerosis Diseases 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- KHYBPSFKEHXSLX-UHFFFAOYSA-N iminotitanium Chemical compound [Ti]=N KHYBPSFKEHXSLX-UHFFFAOYSA-N 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000003698 laser cutting Methods 0.000 description 1
- 238000010329 laser etching Methods 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910001000 nickel titanium Inorganic materials 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 239000004633 polyglycolic acid Substances 0.000 description 1
- 239000004626 polylactic acid Substances 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000010349 pulsation Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000007631 vascular surgery Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Physics & Mathematics (AREA)
- Vascular Medicine (AREA)
- Optics & Photonics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The invention relates to a vascular stent, which comprises a support body and a connector, wherein the support body comprises a plurality of repeating units, the connector comprises a plurality of repeating units, the repeating units of the support body are axially arranged along the stent, and at least one repeating unit is connected between adjacent repeating units of the support body. The vascular stent is particularly suitable for coronary artery, has good supporting effect on the coronary artery, comprises a plurality of repeated units, and can effectively coordinate and deform each repeated unit, so that the axial shrinkage rate can be reduced, and the vascular stent plays a role in accurate positioning during release.
Description
Technical Field
The invention belongs to the field of medical appliances, and particularly relates to a vascular stent.
Background
Coronary atherosclerosis is one of the major cardiovascular diseases that threatens human life in contemporary society. At present, the stent implantation is a main method for treating coronary artery stenosis clinically, and through clinical treatment for more than 20 years, the interventional treatment method is accepted by the vascular surgery field, and meanwhile, patients can also accept the stent implantation due to small wounds, and a plurality of hospitals in China have developed the work.
Currently, tubular stents are the most common type of stent used in coronary stent surgery. In terms of processing technology, the tubular support is generally manufactured by laser engraving or etching a metal tube. In terms of design and structure, the tubular support is generally composed of a support body and a connecting body. The support body and the connector can be divided into two types according to the combination mode of the support body and the connector, and one type is called an open-loop structure, such as a BX-vector bracket designed by Cordis corporation; another type of structure is known as a closed loop structure, such as a Multi-Link stent designed by guilant corporation.
At present, the tubular stent has better supporting property and flexibility, but has some problems:
1) The support body of most support is along support axial symmetry arrangement, and the connector both ends link to each other with the circular arc outside of support body respectively, make support axial dimension shorten when support expansion time support along circumference deformation for the axial shrinkage is higher.
2) The stent support body and the connecting body are composed of straight line segments and circular arc segments, when bending deformation occurs, the deformation capacity is poor, and especially, when the stent is implanted into a bending lesion, the capacity of adapting to a blood vessel is poor, and bad phenomena such as intimal injury or inflammatory reaction can be caused.
3) When the intravascular stent is subjected to periodic blood flow pulsation load, the fatigue strength of the intravascular stent is related to the load, the material and the framework size of the intravascular stent, and animal experiments prove that the fatigue fracture phenomenon caused by insufficient fatigue strength of the intravascular stent occurs.
The vascular stent is used as a heterologous body in a human body for a long time and is closely related to the body health of a patient after treatment. Therefore, the requirements of people on the design and the materials of the stent are nearly ideal, and the higher requirements on the supporting performance, the flexibility, the fatigue life, the hydrodynamic properties and other mechanical properties of the stent are provided, so that research and development and application research of a novel vascular stent are necessary.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide the vascular stent with different structures, which has the advantages of difficult formation of restenosis in blood vessels, good tissue compatibility, proper supporting force on blood vessels, no influence on blood flow, simple structure, convenient operation and accurate positioning, and can meet the clinical requirements on treatment of vascular stenosis.
In order to solve the technical problems, the invention adopts the following technical scheme:
the application relates to a vascular stent, which comprises a supporting body and a connecting body,
the support comprises a plurality of repeating units,
the linker comprises a plurality of repeating monomers,
the plurality of repeating units of the support body are axially arranged along the bracket,
the adjacent repeating units of the support are connected by at least one repeating unit.
Preferably, the repeating units are formed by connecting circular arc sections or broken line sections, and each repeating unit is asymmetrically arranged along the axial direction of the bracket.
Preferably, the repeated monomers are formed by connecting circular arc sections or broken line sections, and each repeated monomer is asymmetrically arranged along the axial direction of the bracket.
Preferably, the multiple repeating units of the support body include multiple first repeating units and multiple second repeating units, the first repeating units and the second repeating units are alternately arranged at intervals, the first repeating units of the support body include multiple first arc sections, adjacent first arc sections are connected through first transition arcs, the bending directions of the multiple first arc sections of the first repeating units are the same, the second repeating units of the support body include multiple second arc sections, adjacent second arc sections are connected through second transition arcs, and the bending directions of the multiple second arc sections of the second repeating units are the same.
Preferably, the radii of curvature of the plurality of first arc segments and the plurality of second arc segments are the same.
Preferably, the first repeat unit is rotated 180 ° from the second repeat unit.
Preferably, the first transition circular arc and the second transition circular arc are staggered by 0.1-0.5 mm in the circumferential direction of the vascular stent.
Preferably, the multiple repeating monomers of the connector include multiple first repeating monomers and multiple second repeating monomers, the bending directions of the multiple first repeating monomers are the same, and the bending directions of the multiple second repeating monomers are the same.
Preferably, one end of the first repeating unit is connected to the outer side of the first excessive arc, and the other end is connected to the inner side of the second excessive arc; one end of the second repeating unit is connected to the outer side of the second excessive arc, and the other end of the second repeating unit is connected to the inner side of the first excessive arc.
Preferably, the first repeating monomer and the second repeating monomer of the linker are rotated 180 °.
Preferably, the first repeating unit and the second repeating unit have the same bending direction of the second arc section; the second repeating unit and the first repeating unit are bent in the same direction.
Preferably, the curvature radius of the first repeating unit and the second repeating unit of the connector is larger than that of the first repeating unit and the second repeating unit of the support body to form a first arc section and a second arc section.
Preferably, the length of the connector in the axial direction of the vascular stent is 1 to 1.5 times of the length of the support in the axial direction of the vascular stent.
Preferably, the number of the first repeating units and the second repeating units of the support is the same, and the number of the units is 4-20.
Preferably, the number of the first repeating monomer and the second repeating monomer of the connector is the same or different, and the number of the monomers is 2-16.
Preferably, the number of repeating units is greater than the number of repeating monomers.
Preferably, the first repeating unit and the second repeating unit are spaced apart from each other by a distance of 0.5 to 3mm in the axial direction of the stent.
Preferably, the width of the repeating unit is 0.05 to 0.3mm.
Preferably, the width of the repeating unit is 40 to 80% of the width of the repeating unit.
Preferably, the wall thickness of the support body and the wall thickness of the connecting body of the vascular stent are the same.
Due to the implementation of the technical scheme, compared with the prior art, the invention has the following advantages:
the vascular stent is particularly suitable for coronary artery, has good supporting effect on the coronary artery, comprises a plurality of repeated units, and can effectively coordinate and deform each repeated unit, so that the axial shrinkage rate can be reduced, and the vascular stent plays a role in accurate positioning during release.
Drawings
FIG. 1 is a schematic view showing the structure of the stent of example 1 in a flat configuration;
FIG. 2 is an enlarged view of a first repeat unit and a second repeat unit;
FIG. 3 is an enlarged view of a first repeat unit;
fig. 4 is an enlarged view of a second repeating unit;
FIG. 5 is an enlarged view of a first repeat unit;
FIG. 6 is an enlarged view of a second repeat unit;
FIG. 7 is a schematic view showing the structure of the stent of example 2 deployed in a plane;
FIG. 8 is a schematic view showing the structure of the stent of example 3 deployed in a plane;
FIG. 9 is a schematic view showing the structure of the stent of example 4 in a flat configuration;
wherein: 1. a first repeat unit; 11 13, a first arc section; 12. a first transition arc; 2. a second repeating unit; 21 23, a second arc section; 22. a second transition arc; 3. a first repeat monomer; 4. a second repeating monomer which is a monomer of the first repeating unit,
l1 the first transition arc 12 and the second transition arc 22 are longitudinally offset in length; l2 the first repeat unit 1 and the second repeat unit 2 are axially spaced apart along the stent; length of the L3 first repeat unit 1; the length of the L4 second repeating unit 2; length of L5 first repeat monomer 3; length of L6 second repeat monomer 4;
radius of curvature of the circular arc segment 11 of the first repeating unit of R1; radius of curvature of the first circular arc segment 13 of the first repeating unit R2; radius of curvature of R3 second repeating unit arc segment 21; radius of curvature of R4 second repeating unit arc segment 23; radius of curvature of R5 first repeat monomer 3; radius of curvature of R6 second repeating monomer 4;
c1 stent centerline.
Detailed Description
The present invention will be described in further detail with reference to the following examples, but the present invention is not limited to the following examples.
The vascular stent of the invention is mainly applicable to blood vessels of human bodies, in particular to coronary arteries (as shown in figure 1). In the process of implanting the vascular stent into the coronary artery, the vascular stent is arranged on a balloon of a stent conveying system, at the moment, the vascular stent is in a compressed state, after the vascular stent is conveyed to a lesion position by a conveyor, the balloon is filled by a pressure pump, the vascular stent is expanded outwards to an expanded state, so that the coronary artery is supported, the vascular stent has a first cross section in the compressed state and a second cross section in the expanded state, and the diameter of the first cross section is smaller than that of the second cross section. In the present invention, the first cross section and the second cross section are perpendicular to the axis of the stent. In this embodiment, the outer diameter of the second cross section is 2 to 8mm, preferably 2 to 5mm.
The vascular stent is made of one or more of stainless steel, memory alloy, titanium alloy, tantalum alloy, cobalt-chromium alloy, biodegradable metal, biodegradable polymer, magnesium alloy and pure iron. As the stainless steel, SUS-316L stainless steel or the like can be used. The memory alloy can be Ni-Ti alloy, cu-Al-Mn alloy, etc. The cobalt-chromium alloy can be CoCr-L605 cobalt-chromium alloy, etc. Biodegradable metal is a metal that can be decomposed in the human body, such as pure magnesium, magnesium alloy, pure iron, iron alloy, and the like. The biodegradable polymer may be polylactic acid, polyglycolic acid, poly (lactic acid-epsilon-caprolactone), poly (glycolic acid-epsilon-caprolactone), or other biodegradable polymers. In addition, biodegradable polymer material may be coated onto degradable metal to form vascular rack.
The vascular stent can be molded at one time by laser engraving. The production process of laser engraving comprises the following steps: firstly, creating a cutting path by utilizing CAM based on a stent design drawing; secondly, carrying out laser cutting on the metal or high polymer material; finally, the surface finish is improved through acid washing and electrochemical processes, so that the shape of each edge is round.
As shown in fig. 1, in an intravascular stent according to a first embodiment of the present application, the intravascular stent includes a support body and a connector, the support body includes a plurality of repeating units, the connector includes a plurality of repeating units, the plurality of repeating units of the support body are arranged along an axial direction of the stent, and at least one repeating unit is connected between adjacent repeating units of the support body. The plurality of repeating units of the support body comprise a plurality of first repeating units 1 and a plurality of second repeating units 2, the first repeating units 1 and the second repeating units 2 are alternately arranged at intervals, and the first repeating units 1 are obtained by rotating the second repeating units 2 by 180 degrees. The multiple repeated monomers of the connector comprise a plurality of first repeated monomers 3 and second repeated monomers 4, and the first repeated monomers 3 and the second repeated monomers 4 of the connector are obtained by rotating 180 degrees. The first repeating unit 1 is provided with a first transition arc 12, the second repeating unit 2 is provided with a second transition arc 22, and the first transition arc 12 and the second transition arc 22 are staggered by 0.1-0.5 mm in the circumferential direction. The first repeating unit 1 and the second repeating unit 2 of the support body are asymmetrically arranged along the axial direction of the support, and are axially spaced by 0.1-0.5 mm. The adjacent repeating units of the support are connected by at least one first repeating monomer 3 or second repeating monomer 4. The number of the first repeating units 1 and the second repeating units 2 of the support body is the same, and the number of the units is 4-20. The number of the first repeating monomer 3 and the second repeating monomer 4 of the connector is the same or different, and the number of the monomers is 2-16. The number of the first repeating units 1 and the second repeating units 2 of the support is greater than the number of the first repeating units 3 and the second repeating units 4 of the connector. In this embodiment, the repeating unit of the support body and the repeating unit of the connector are formed by connecting arc segments. The first repeating unit 1 of the support body comprises a plurality of first arc sections 11, 13, wherein adjacent first arc sections 11, 13 are connected through a first transition arc 12, the second repeating unit 2 comprises a plurality of second arc sections 21, 23, adjacent second arc sections 21, 23 are connected through a second transition arc 22, and the curvature radiuses of the plurality of first arc sections 11, 13 and the plurality of second arc sections 21, 23 are the same. The bending directions of the first arc segments 11, 13 of the first repeating unit 1 are the same, and the bending directions of the second arc segments 21, 23 of the second repeating unit 2 are the same. One end of the first repeating unit 3 is connected to the outer side of the first transition circular arc 12, and the other end is connected to the inner side of the second transition circular arc 22; one end of the second repeating unit 4 is connected to the outer side of the second transition circular arc 22, and the other end is connected to the inner side of the first transition circular arc 12. The bending direction of the first repeating unit 1 is the same as that of the second circular arc sections 21 and 23 of the second repeating unit 4; the second repeating unit 2 is bent in the same direction as the first circular arc sections 11, 13 of the first repeating unit 3. The curvature radius of the first repeating unit 3 and the second repeating unit 4 of the connector is larger than that of the first repeating unit 1 and the second repeating unit 2 of the support. The distance between the first repeating unit 1 and the second repeating unit 2 of the support body in the axial direction of the vascular stent is 0.5-3 mm. The distance between the first repeating unit 3 and the second repeating unit 4 of the connector in the longitudinal direction is 1 to 1.5 times of the length of the first repeating unit 1 and the second repeating unit 2 of the support in the axial direction. The width of the first repeating unit 1 and the second repeating unit 2 of the support body is 0.05-0.3 mm. The lengths of the first repeating unit 3 and the second repeating unit 4 of the connector in the axial direction of the vascular stent are 40-80% of the widths of the first repeating unit 1 and the second repeating unit 2 of the support. The wall thickness of the support body and the wall thickness of the connecting body of the vascular stent are the same.
The specific effects of the present embodiment are as follows:
1) The axial shrinkage rate is low: the support body of the vascular stent comprises a plurality of repeating units, the first repeating units and the second repeating units are alternately arranged at intervals, the adjacent repeating units of the support body are connected by at least one connecting body consisting of circular arcs or folding lines, and each repeating unit can effectively coordinate and deform, so that the axial shrinkage rate can be reduced, and the function of accurate positioning is realized during release.
2) The adaptability to blood vessels is strong: the repeated units of the support body and the repeated units of the connector of the vascular stent are connected by circular arcs or fold lines, so that the vascular stent has the advantages of strong deformability, good flexibility, good capability of adapting to blood vessels, accurate release and simple operation.
3) High fatigue strength: the adjacent repeating units of the support body of the vascular stent are connected by at least one first repeating unit or one second repeating unit, the curvature radiuses of the circular arc sections are the same, the bending directions are the same, and the load can be effectively dispersed by each repeating unit, so that the fatigue strength can be improved.
The above contents of example 2 and example 1 are the same, and the difference is only that: in example 1, the repeating units of the support and the repeating units of the linker are all connected by circular arc segments, as shown in fig. 1 to 6. In example 2, the repeating units of the support and the repeating units of the linker are all connected by a polyline, as shown in FIG. 7.
Example 3 and example 1 are the same as described above, with the only differences being: in example 1, the repeating units of the support and the repeating units of the linker are all connected by circular arc segments, as shown in fig. 1 to 6. In example 3, the first repeating unit 1 and the second repeating unit 2 of the support body are connected by an arc segment, and the first repeating unit 3 and the second repeating unit 4 of the connection body are connected by a broken line segment, as shown in fig. 8.
The above contents of example 4 and example 1 are the same, and the difference is only that: in example 1, the repeating units of the support and the repeating units of the linker are all connected by circular arc segments, as shown in fig. 1 to 6. In example 4, the first repeating unit 1 and the second repeating unit 2 of the support body are connected by a broken line segment, and the first repeating unit 3 and the second repeating unit 4 of the connection body are connected by an arc segment, as shown in fig. 9.
The vascular stent is particularly suitable for coronary artery, has good supporting effect on the coronary artery and small damage on the wall of the coronary artery, can effectively avoid the formation of restenosis in the blood vessel after the vascular stent is implanted, can well position in the coronary artery, improves the releasing accuracy, is simple and convenient to operate, has simple structure, is convenient to produce and has low cost, thereby having important practical significance and good clinical application prospect.
The present invention has been described in detail with the purpose of enabling those skilled in the art to understand and practice the present invention, but not to limit the scope of the present invention, and the present invention is not limited to the above-described embodiments, and all equivalent changes or modifications according to the spirit of the present invention should be covered in the scope of the present invention.
Claims (5)
1. A vascular stent, characterized in that: the vascular stent comprises a supporting body and a connecting body,
the support body comprises a plurality of repeating units, the repeating units are formed by connecting circular arc sections or broken line sections, each repeating unit is asymmetrically arranged along the axial direction of the support, the connector comprises a plurality of repeating monomers, each repeating monomer is formed by connecting circular arc sections or broken line sections, and each repeating monomer is asymmetrically arranged along the axial direction of the support;
the multiple repeated monomers of the connector comprise multiple first repeated monomers and multiple second repeated monomers, the bending directions of the multiple first repeated monomers are the same, the bending directions of the multiple second repeated monomers are the same, and the first repeated monomers are obtained by rotating the second repeated monomers by 180 degrees;
the plurality of repeating units of the support body are axially arranged along the bracket,
the adjacent repeating units of the support body are connected by at least one repeating monomer;
the multiple repeating units of the support body comprise multiple first repeating units and multiple second repeating units, wherein the first repeating units are obtained by rotating the second repeating units by 180 degrees;
the first repeating units and the second repeating units are alternately arranged at intervals,
the first repeating unit of the support body comprises a plurality of first arc sections, the adjacent first arc sections are connected through a first transition arc, the bending directions of the plurality of first arc sections of the first repeating unit are the same,
the second repeating unit of the support body comprises a plurality of second arc sections, the adjacent second arc sections are connected through a second transition arc, and the bending directions of the plurality of second arc sections of the second repeating unit are the same; the curvature radiuses of the first arc sections and the second arc sections are the same.
2. A vascular stent as defined in claim 1, wherein: one end of the first repeating unit is connected to the outer side of the first excessive arc, and the other end of the first repeating unit is connected to the inner side of the second excessive arc; one end of the second repeating unit is connected to the outer side of the second excessive arc, and the other end of the second repeating unit is connected to the inner side of the first excessive arc.
3. A vascular stent as defined in claim 2, wherein: the curvature radius of the first repeating unit and the second repeating unit of the connecting body is larger than that of the first repeating unit and the second repeating unit of the supporting body.
4. A vascular stent as defined in claim 1, wherein: the width of the repeating unit is 40-80% of the width of the repeating unit.
5. A vascular stent as defined in claim 1, wherein: the wall thickness of the support body and the wall thickness of the connecting body of the vascular stent are the same.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710970707.9A CN107550611B (en) | 2017-10-18 | 2017-10-18 | Vascular stent |
| PCT/CN2017/109266 WO2019075790A1 (en) | 2017-10-18 | 2017-11-03 | Blood vessel stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710970707.9A CN107550611B (en) | 2017-10-18 | 2017-10-18 | Vascular stent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107550611A CN107550611A (en) | 2018-01-09 |
| CN107550611B true CN107550611B (en) | 2024-03-15 |
Family
ID=60986333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710970707.9A Active CN107550611B (en) | 2017-10-18 | 2017-10-18 | Vascular stent |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN107550611B (en) |
| WO (1) | WO2019075790A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109793941A (en) * | 2019-01-08 | 2019-05-24 | 科塞尔医疗科技（苏州）有限公司 | A kind of hydrophilic coating solution of medical catheter and preparation method thereof and application method |
| DE102019112971A1 (en) * | 2019-05-16 | 2020-11-19 | Optimed Medizinische Instrumente Gmbh | STENT |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3146103U (en) * | 2008-07-08 | 2008-11-06 | 株式会社日本ステントテクノロジー | Stent |
| CN102813566A (en) * | 2012-04-24 | 2012-12-12 | 冯海全 | Coronary stent |
| CN103550017A (en) * | 2013-08-16 | 2014-02-05 | 江苏大学 | Intravascular stent applicable to conical blood vessel |
| CN204600807U (en) * | 2015-04-27 | 2015-09-02 | 日照天一生物医疗科技有限公司 | Magnesium alloy blood vessel rack |
| CN106859821A (en) * | 2017-03-15 | 2017-06-20 | 大连理工大学 | A kind of biodegradable polymer intravascular stent of injection moulding |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3654627B2 (en) * | 2000-04-20 | 2005-06-02 | 川澄化学工業株式会社 | Stent |
| US8109987B2 (en) * | 2003-04-14 | 2012-02-07 | Tryton Medical, Inc. | Method of treating a lumenal bifurcation |
| CN201085705Y (en) * | 2007-09-03 | 2008-07-16 | 江苏瑞上医疗器械有限公司 | Laser engraved blood vessel support rigid in radial direction and flexible in longitudinal direction |
| PL218676B1 (en) * | 2009-04-23 | 2015-01-30 | Balton Spółka Z Ograniczoną Odpowiedzialnością | Bifurcation stent and the system for intravascular implanting of the bifurcation stent |
| CN103300951A (en) * | 2013-06-17 | 2013-09-18 | 苏州爱瑞德医疗科技有限公司 | Vertebral artery stent |
| CN106691647B (en) * | 2015-07-20 | 2019-05-24 | 上海交通大学 | A kind of biodegradable metals intravascular stent and its application |
-
2017
- 2017-10-18 CN CN201710970707.9A patent/CN107550611B/en active Active
- 2017-11-03 WO PCT/CN2017/109266 patent/WO2019075790A1/en active Application Filing
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3146103U (en) * | 2008-07-08 | 2008-11-06 | 株式会社日本ステントテクノロジー | Stent |
| CN102813566A (en) * | 2012-04-24 | 2012-12-12 | 冯海全 | Coronary stent |
| CN103550017A (en) * | 2013-08-16 | 2014-02-05 | 江苏大学 | Intravascular stent applicable to conical blood vessel |
| CN204600807U (en) * | 2015-04-27 | 2015-09-02 | 日照天一生物医疗科技有限公司 | Magnesium alloy blood vessel rack |
| CN106859821A (en) * | 2017-03-15 | 2017-06-20 | 大连理工大学 | A kind of biodegradable polymer intravascular stent of injection moulding |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107550611A (en) | 2018-01-09 |
| WO2019075790A1 (en) | 2019-04-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4871692B2 (en) | In vivo indwelling stent and biological organ dilator | |
| US7273495B2 (en) | Intravascular stent and method of use | |
| US8114149B2 (en) | Hybrid stent with helical connectors | |
| US7331987B1 (en) | Intravascular stent and method of use | |
| US20090043374A1 (en) | Stent to be Placed in the Living Body | |
| CN105726174B (en) | A kind of intravascular stent, preparation method and application | |
| JP2009538687A (en) | Stent with retention protrusions formed during crimp | |
| CN204951247U (en) | Biodegradable metal blood vessel support | |
| CN106691647B (en) | A kind of biodegradable metals intravascular stent and its application | |
| CN107550611B (en) | Vascular stent | |
| US20200206004A1 (en) | Absorbable stent | |
| CN106176003B (en) | A kind of intravascular stent, preparation method and application | |
| CN108670510B (en) | Intracranial vascular stent with excellent flexibility | |
| US20200276035A1 (en) | Intravascular stent, preparation method and use thereof | |
| US10695201B2 (en) | Intravascular stent, preparation method and use thereof | |
| US20080234800A1 (en) | Stent Including a Toggle Lock | |
| EP3578142B1 (en) | Bioabsorbable stent | |
| US8192483B2 (en) | Stent to be placed in the living body | |
| CN209611445U (en) | A kind of intravascular stent | |
| CN219230280U (en) | Vascular stent | |
| CN220459458U (en) | Vascular stent | |
| CN107088113A (en) | A kind of complicated brace rod intravascular stent | |
| RU2350301C1 (en) | Straightened intravascular stent | |
| CN113648113B (en) | Degradable support | |
| CN102657564B (en) | Biodegradable vascular scaffold |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |