CN102813566A - Coronary stent - Google Patents
Coronary stent Download PDFInfo
- Publication number
- CN102813566A CN102813566A CN201210141095XA CN201210141095A CN102813566A CN 102813566 A CN102813566 A CN 102813566A CN 201210141095X A CN201210141095X A CN 201210141095XA CN 201210141095 A CN201210141095 A CN 201210141095A CN 102813566 A CN102813566 A CN 102813566A
- Authority
- CN
- China
- Prior art keywords
- shaped support
- support
- annular
- type
- types
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Abstract
The invention discloses a coronary stent. The coronary stent structurally comprises a tubular body structure which is formed by a first class circular unit and a second class circular unit alternatively arranged in sequence along an axial direction, wherein the tubular body structure comprises a bracket with an extensible property along a radius direction; the first class circular unit and the second class circular unit are circular units formed by U-shaped brackets which are provided with openings at one end along the axial direction and connected in series; the opening direction of the U-shaped opening of the U-shaped bracket adjacent to the circular units is an opposite direction; each U-shaped bracket is composed of a line segment and an arc segment, and the U-shaped bracket of the first class circular unit and a part of the corresponding arc segment adjacent to the U-shaped bracket of the second class circular unit are connected by a corresponding connection arc. The coronary stent has the characteristics of good endurance bending strength and high flexibility.
Description
Technical field
The present invention relates to a kind of coronary artery bracket, belong to medical instruments field.
Background technology
In recent years, to the artery occlusion that atherosclerosis causes, implant expandable stent, the Therapeutic Method of promoting blood flow is popularized rapidly, for the patient has brought Gospel.This support that is used to treat needs to satisfy 3 requirements.The first, with the support of closure, carry far-end at the expansion type foley's tube, along inserting endarterial seal wire in advance, be delivered to block part.Therefore, through narrow tremulous pulse the time, require support that enough pliabilities must be arranged.Secondly, expanded stent should have enough support forces to support arterial wall and enough intensity keeps the unobstructed of its narrow, and the fatigue strength that bears the crooked varying load that heart pulse rate causes must be arranged.The 3rd, be shorter than through the stent length of balloon expandable and press the length of holding state, i.e. support expansion back length can shorten, and this might make treatment can not cover whole lesion region, so require the length variations before and after the support expansion little.
The Expansion support of the Boston Scientific Corporation company that the planform that Fig. 3 is in the market to be sold is similar circumferentially connects into one type of annular unit 8 by one type of supporter 7; Two types of annular units 8 of a plurality of two types of supporters 7 ' circumferentially connect into ', be the center with the axis C1 of support 6, alternate configurations.The number of the U-shaped structure of two types of annular units is 1.5 times of number of the U-shaped structure of said one type of annular unit.First and second annular units 8,8 ' connect through straight line connecting rod 9.Connect arc structure and cause expansion pressure to increase, fatigue strength reduces.Support Design to traditional is furtherd investigate, and the support that patent documentation 1 (Japanese Patent No. 3654627) and patent documentation 2 (Japanese Patent No. 3663192) closed loop design cause bending stiffness and fatigue strength to be mentioned in low goes out for conventional stent designs is as shown in Figure 7.Patent documentation 1 is that a plurality of supporters 11 are along circumferentially being connected with the supporting structure shown in 2; Supporter 11 is that the axle center encompasses unit 12 with the axis C1 of support 15; Adjacent annular unit 12,12 ' through corresponding supporter 11,11 ' connect at corresponding S shape interface 14.
Patent documentation 1 has good crooked deformability with patent documentation 2, and can guarantee the unobstructed of narrow positions.But, carry out finding after the finite element analysis that maximum stress occurred in 13 places, top of S shape connecting rod when support bore bending load.Fatigue test results shows, the fatigue strength at 13 places is relative 11,11 ' and the straightway of S shape connecting rod is poor.In the support interventional therapeutic technique, the stress that support bore is very complicated, and distortion such as also have tension and compression and reverse is so the bending fatigue strength of such support and bending stiffness aspect exist defective.
Another supporting structure is shown in patent documentation 3 (No. 3145720, Japanese Utility Model registration) the said support (like Fig. 5).This supporting structure circumferentially connects into one type of annular unit 8 by a plurality of one type of supporter 7; Two types of annular units 8 of a plurality of two types of supporters 7 ' circumferentially connect into ', be the center with the axis C1 of support 6, alternate configurations.First and second annular units 8,8 ' connect through junction point 9, this first kind supporter and second type of supporter are the center with junction point 9, along the axis direction symmetry of support 6, and the supporter at the disconnected relatively point of the supporter at junction point place place is slightly long.
Patent documentation 3 (as shown in Figure 5) though enough bending fatigue strengths are arranged, required pressure in the support process of expansion, higher than the needed pressure of conventional stent illustrated in fig. 7, this show this support difficulty open.Therefore, the described support of patent documentation 3 (as shown in Figure 5) has problems aspect dilatancy.
In addition, in the support of being sold in the market shown in Figure 81 (S-Stent), unit 16,16 ' be to connect by junction point 17, element length is constant, the length of junction point 17 is about 0.2 millimeter.The supporter 18,18 of support 2 shown in Figure 9 (Driver) ' be to form by cochrome steel wire Z type bend fixing, junction point 19 is through being welded to connect.
Fig. 3, there is defective equally in other support shown in 8 and 9 aspect dilatancy.
Summary of the invention
The object of the present invention is to provide a kind ofly, be convenient to be transported in the narrow and zigzag arteries, have good pliability, spreading performance, keep the unobstructed support strength of tremulous pulse, and can bear a kind of coronary artery bracket of the flexural fatigue load that pulse causes.
The object of the invention is implemented by following technical scheme: a kind of coronary artery bracket; It is axially alternately to arrange successively by one type of annular unit and two types of annular units and forms the tubular body structure; Said tubular body structure has the support of expansible performance along radial direction; Said one type of annular unit and said two types of annular units all are annular units that the U-shaped support serial connection an end opening in axial direction is formed by connecting; And the opening direction of the U-shaped mouth of the U-shaped support that said annular unit is adjacent is a rightabout, and said U-shaped support is made up of straightway and arc section; Part in the adjacent corresponding circle segmental arc of the U-shaped support of said one type of annular unit and the U-shaped support of said two types of annular units connects with corresponding connection circular arc.
This coronary artery bracket, the number of the U-shaped support of said two types of annular units be said one type of annular unit the U-shaped support number 1.4-1.6 doubly.
This coronary artery bracket, the length of straigh line of the U-shaped support of said one type of annular unit be said two types of annular units U-shaped support length of straigh line 1.4-1.6 doubly.
This coronary artery bracket; The radius of curvature of the arc section of each U-shaped support that said one type of annular unit and said two types of annular units participate in being connected is said one type of annular unit has neither part nor lot in 1.1-1.5 times of radius of curvature of each the U-shaped support arc section that is connected with said two types of annular units.
The width of the straightway of each the U-shaped support in this coronary artery bracket, said one type of annular unit and said two types of annular units be have neither part nor lot in the width that is connected arc section 1.1-1.5 doubly.
This coronary artery bracket; The length of straigh line of each U-shaped support that said one type of annular unit and said two types of annular units participate in being connected has neither part nor lot in the length increase 10-25% of straightway of each U-shaped support of said one type of annular unit and said two types of annular units of connection relatively.
This coronary artery bracket, each said one type of annular unit is made up of 6-10 U type support.
This coronary artery bracket, said one type of annular unit is 1-3 with the number of the U-shaped support that said two types of annular units participation is connected.
This coronary artery bracket, the U-shaped support of said one type of annular unit and the U-shaped support of said two types of annular units are tangent connections of center circular arc through the U-shaped support of the center circular arc of the U-shaped support of said one type of annular unit and said two types of annular units.
This coronary artery bracket, said U-shaped support be by rustless steel, cochrome, Nitinol, any material of biodegradable polymers material or biodegradable metal, pure magnesium, magnesium alloy, pure iron or ferroalloy.
A kind of coronary artery bracket; It is axially alternately to arrange successively by one type of annular unit and two types of annular units and forms the tubular body structure; Said tubular body structure has the support of expansible performance along radial direction; Said one type of annular unit and said two types of annular units all are annular units that the U-shaped support serial connection an end opening in axial direction is formed by connecting; And the opening direction of the U-shaped mouth of the U-shaped support that said annular unit is adjacent is a rightabout; Said U-shaped support is made up of straightway and arc section, said arc section comprise in order to be connected with the straightway transition tangent circle segmental arc with in order to be connected the connection arc section of one, two type of annular unit U-shaped support, the radius of curvature of said connection arc section is greater than the radius of curvature of tangent circle segmental arc.
A kind of method of making coronary artery bracket may further comprise the steps: at first, according to the structure of design support, utilize CAM to create cutting path; Secondly, metal or macromolecular material are carried out cut, by being laser-cut into shape of a mesh; At last, with the support after the cut, the metal with oxidation dissolves in acid solution earlier, carries out electrobrightening afterwards, makes each edge shape mellow and full.
The invention has the advantages that: this support is the support that is used to improve angiostenosis, and characteristics are that fatigue strength is high, and pliability is good." support " among the present invention is to be used for expanding intravital blood vessel, reaches the purpose of keeping expansion, and support has used biocompatible materials.Generally speaking, this support and special-purpose sacculus together are implanted to desired position in the body, and during inflation, support is expanded, thereby reaches the purpose of support blood vessels.
Description of drawings:
Fig. 1 is a plane outspread drawing of coronary artery bracket of the present invention.
Fig. 2 is the coupling part partial enlarged drawing of Fig. 1.
Fig. 3 is a kind of plane outspread drawing of traditional coronary artery bracket.
Fig. 4 is the coupling part partial enlarged drawing of Fig. 3.
Fig. 5 is the plane outspread drawing of another kind of traditional coronary artery bracket.
Fig. 6 is the coupling part partial enlarged drawing of Fig. 5.
Fig. 7 is the plane outspread drawing of another traditional coronary artery bracket.
Fig. 8 is that the annular unit of listing product at present connects synoptic diagram.
Fig. 9 is that the annular unit of listing product at present connects synoptic diagram.
Figure 10 is for forming the synoptic diagram of support U-shaped support.
Figure 11 is bending fatigue strength test synoptic diagram.
Figure 12 stress envelope.
Figure 13 circular arc portion partial enlarged drawing.
Symbol description
1 support
2,2 ' supporter
3,3 ' annular unit
4 connecting portions
5 supporter arc sections
6 conventional stent (comparative example 2,3)
7,7 ' supporter
8,8 ' annular unit
9 connecting portions
10 supporter arc sections
11,11 ' supporter
12,12 ' annular unit
13 connector arc sections
14 connectors
15 conventional stent (comparative example 1)
16,16 ' supporter
17 connecting portions
18,18 ' supporter
19 connecting portions
20,20 ' center circular arc
21,21 ' tangent line circular arc
22,22 ' arc section
23,23 ' tangent circle segmental arc
24,24 ' straightway
C1 carriage center axle
Fig. 1 does
The specific embodiment
At first the bending fatigue strength research to arc section in the supporting structure draws, the state the when maximum stress of arc section appears at balloon expandable stent in the structure and in the use during pulse bending load.Maximum stress depends on the structure of coupling part, through structure optimization, can reach when guaranteeing expanding ability the fatigue strength that bears bending load is significantly improved.
Through further discovering; The radius of curvature on arc section arc top is greater than the structure of the radius of curvature of straightway and arc section tangent arc, when support bears bending load, and distributed stress strain more equably; Improve bending fatigue strength; Reduce load pressure, make the expansion pressure of standard obtain descending, the expansion uniformity also is improved.
Therefore, the present invention comprises the open U font structure of axial direction one end of arc section and straightway, is connected to form annular unit.A plurality of unit are connected to form the tubular body of support, and support can radially be upheld from inside to outside.Two types of unit that one type of unit that a plurality of class formations circumferentially are connected to form and a plurality of two class formations circumferentially are connected to form are along support axis alternate configurations.And this type of unit and two types of unit profiles are centrosymmetry with its junction point on axis direction.So-called junction point is that an one of corresponding circular arc has participated in connection.The radius of curvature of the arc section that participate in to connect in the unit be the not radius of curvature of junction point place arc section 1.1-1.5 doubly, the width of unit cathetus section be have neither part nor lot in connection arc section width 1.1-1.5 doubly.Wherein, optimum range is 1.2-1.4 times.
The number of the U-shaped support of two types of annular units of support be one type of annular unit the U-shaped support 1.4-1.6 doubly, the straightway of the U-shaped support of one type of annular unit be two types of annular units U-shaped support straightway 1.4-1.6 doubly.
Interconnected two structures of support, the equal in length of its line part, and slightly more longer than the line part of the structure that has neither part nor lot in connection.Generally; The line part length of junction point is than the line part long 10% to 25% of the structure that has neither part nor lot in connection; Length is the U-shaped support of 1.2mm, and length difference is about
The straightway width of the U-shaped support of one type of annular unit of support is the 1.1-1.5 support doubly of the U-shaped support straightway width of two types of annular units.Wherein, optimum range is 1.2-1.4 times.
Each annular unit of support is made up of 6-10 U-shaped support, and comparatively ideal situation is, 1-3 wherein structure participates in connecting.
Above-mentioned support can be to add the wire junctional complex in the middle of two arc structures to connect during connection, but it would be desirable that corresponding two circular arcs directly are connected to form junction point, and, be junction point preferably with circular arc arc top.The width of U-shaped support and coupling part and thickness require constant as far as possible.
The material of support should be rustless steel or cochrome material, or is processed by biodegradable metal or macromolecular material.Pure magnesium, magnesium alloy, pure iron or ferroalloy etc. are arranged in the degradable metal.
[invention effect]
The present invention utilizes S shape junction point (junction point 14 among Fig. 7) between the structure with respect to traditional support, removed S shape syndeton, is connected by the part of corresponding U-shaped support.Because all structures of support; The radius of curvature that its arc that constitutes arc section pushes up is bigger than the radius of curvature of the tangent arc of straightway and arc section; The U-shaped support number of two types of annular units is more than the U-shaped support number of one type of annular unit; The straightway of the U-shaped support of one type of annular unit is longer than the U-shaped support straightway of two types of annular units, and the width of unit cathetus section is bigger than the width of the arc section that has neither part nor lot in connection.Realized that ess-strain is evenly distributed, and has improved bending fatigue strength.In addition, the present invention has only the structure of part to participate in connection, its structure as stated, thereby make the expansion pressure of standard obtain descending, when not influencing autgmentability, significantly improved bending fatigue strength.
[explanation of sketch]
Introduce the concrete shape of support with reference to the accompanying drawings in detail.Fig. 1 is a plane outspread drawing of support of the present invention.Fig. 2 is the coupling part partial enlarged drawing of support shown in Figure 1.As shown in Figure 1, along the open U-shaped support 2,2 of axial direction one end of support ', form circulus 3 and 3 ' axially-aligned around the central shaft C1 circumferential arrangement of support 1.Be connected to form tubular structure through connecting portion 4.Tubular body can from inside to outside be upheld and the U-shaped support is made up of straightway and arc section 5.
This support; A plurality of one type of U-shaped support 2 are connected to form one type of annular unit 3 with circumferencial direction and are connected to form two types of annular units 3 ' with a plurality of two types of U-shaped supports 2 ' with circumferencial direction and alternately are connected, and form tubular body, and; Two types of U-shaped supports are the center with junction point 4, symmetric arrangement.Part in a plurality of U-shaped supports of annular unit 3 and 3 ' correspondence is connected at junction point 4 places.Part type of attachment and all corresponding point type of attachment contrasts, pliability is improved.The junction point 4 ' of one type of annular unit 3 and 3 ' junction point 4 and adjacent annular unit 3 and 3 ' the corresponding configuration of row such as C 1 direction vertically, thus make the generation of support minimizing non-uniform phenomenon when expanding.In the present invention; As connector can be that the connector of 0.1～0.3mm connects by length; But ideal is to participate in the straightway of the U-shaped support of connection and slightly be longer than the straightway of not participating in syndeton, thereby the arc top of corresponding circle segmental arc directly is connected to form one.If through the connection of short lines, maximum stress will appear at collinear middle part, will descend to the ability to bear of bending load; And adopt arc to push up direct-connected form; Maximum stress occurs in the position, 4 place on every side of connecting portion, thereby reduces maximum stress, improves bearing capacity.At this moment, slightly more longer than the straightway of the U-shaped support that does not connect, help improving the expansion uniformity.The equal in length of junction point both sides straightway, when expansion, angle equates, thereby guarantees the expansion uniformity.Therefore, in the U-shaped support 2,2 ' of correspondence; By the structure that connecting portion 4 connects, very close to each other, the structure that has neither part nor lot in connection is as shown in Figure 1; Form the gap between the arc section, and this gap is the straightway of the structure of participating in connection and the length difference of the straightway that has neither part nor lot in the structure that is connected.Because this small gap exists, to have avoided when support bending and pressure are held, structure is not overlapping.And during support flexural deformation, the adjacent supports body can not interfere phenomenon.Usually, the length of the straightway of the structure of participation connection is than the straight line segment length 10% to 25% of the structure that has neither part nor lot in.Less than 10% o'clock, more than the effect mentioned can not give full play to, and surpass at 25% o'clock, relatively poor to the uniformity of vessel support.In addition, when length difference is excessive, the expansion uniformity is affected, the stress of connecting portion is increased.
This support, the radius of curvature of arc top portion that constitutes the arc section 5 of annular unit do, 1.1～1.5 times of the radius of curvature of the straightway of U-shaped support 2,2 ' and arc section tangent arc 21,21 ', and 1.2～1.4 be the best.Thereby; The maximum stress value at place, the arc top of arc section descends when bearing bending load, and the ability of bearing flexural fatigue load is improved, and the uniformity of the stress deformation when making expansion simultaneously improves; The relative traditional product of standard expansion pressure is improved, and has strengthened the safety of dilation procedure.When the multiplying power of radius of curvature is lower than 1.1 times, can not effectively reduce the maximum stress value that occurring in arc top, and when surpassing 1.5 times, the intersection of straightway and arc section will produce stress, fatigue strength can be affected.In addition, when surpassing 1.5 times, the profile on arc top when pressure is held support, will produce interference between the arc section with excessive.U-shaped support 2,2 ' is after support expansion, and when being the obtuse angle with the angle of central shaft C1, the radial support power of support increases.The angle theta that two straightways of the U-shaped support after the expansion form during near 120 ° radial support power will increase.Promptly; During the design support; When support was expanded to
, the angle θ after the expansion of structure will design more than 50 ° at least.
The size of this support (stent length and diameter) has no particular limits, and is consistent with conventional stent.Under not expansion situation; Length is
millimeter approximately, and is comparatively desirable in the scope of diameter about
.The length of a ring-type unit of support, general
approximately millimeter.A connecting portion length (non-connecting U-shaped bracket between the axial length of the gap) is about
The most ideal length is
The number of the circumferencial direction configuration of U-shaped support 2,2 ' is more than 4 or 4 as far as possible.And; If the diameter after the expansion is greater than more than
; Then should get between the 6-12 usually more than more than 6 or 6.Annular unit 3,3 ' along circumferentially configuration, and total should be got more than 6, gets between the 9-18 usually.Make progress at support shaft, every 10mm configuration is generally 4-8 more than 3.When support is expanded to aimed dia (for example
); Above-mentioned θ at least should be more than 50 ℃; Be generally
though favourable to the support force of support when surpassing 120 °, the distortion of arc section is excessive.And expansion causes support shaft to become big to LVFS, and the implantation position of support will be difficult to confirm.
Unitary support (two straightways) part should distribute in radial symmetric along support axis C1 is shown in figure 10.The thickness of the U-shaped support 2 of support generally should be consistent.Cobalt-chromium alloy stent width is generally
thickness of
stainless steel structure 2 the width of the bracket is usually
thickness of
Among the present invention, the width and the thickness at annular unit 3 and 4 places, coupling part should be constant.Width and constant thickness are convenient to processing, are easier to controlling dimension in the polishing process.Simultaneously, because constant dimension, make cross-sectional area constant, thereby make the moment of flexure of optional position impartial, the pliability of support not the recipient to influence.Particularly, when corresponding U-shaped support directly connects, arc section 20,20 ' summit is overlapping, the uniformity of expansion will be improved (with reference to figure 2) when width is consistent.
This support has been avoided the stress concentration of connecting portion office, thereby has been improved ruggedness and motility owing to have the version of above-mentioned coupling part 4, and pliability and autgmentability are not affected simultaneously.In addition, corresponding U-shaped support 2,2 ' is not whole connections (part connecting-types), and when when blood vessel is carried, even the diameter of support dwindles to some extent, 2,2 ' also are unlikely on the radial direction of support, to form three-dimensional stack.
Support of the present invention shown in Fig. 1 and 2 constitutes the coupling part 4 of annular unit 3,3 ' U-shaped support 2,2 ', on the circumferencial direction of support, should have a point to connect at least.As stated, according to the difference of stent diameter, to confirm in the number of the U-shaped support of circumferencial direction configuration.Generally, when diameter was 3～6mm, the U-shaped support was got 6-10, and this moment, junction point was generally got 1-3.Among the present invention, a part participates in connecting in the corresponding U-shaped support 2,2 ', and all the other are for having neither part nor lot in connection.The existence of this disconnected structure makes support become more pliable and tougher, when bifurcated appears in blood vessel; Guidance quality is improved; Simultaneously disperseed stress owing to form the arc section of coupling part, thereby the coupling part support that do not have a gap configuration is compared relatively, fatigue strength is improved.
Support of the present invention, by rustless steels such as SUS-316L, marmems such as Ni-Ti alloy, Cu-Al-Mn alloy, titanium alloy, tantalum alloy, cochrome manufacturing.
In addition, support of the present invention also can be a kind of metal that can in human body, decompose (biodegradable metals).The degradable metal comprises pure magnesium, magnesium alloy, pure iron and ferroalloy etc.
In addition, material of the present invention can be polylactic acid, polyglycolic acid also, gather (lactic acid-6-caprolactone), gathers Biodegradable polymerics such as (glycolic-6-caprolactones).
In addition, on the degradable metal, coat a kind of biodegradable polymer material in vivo.
Support of the present invention, shape as stated, the geometry of this support can be utilized laser engraving, one-shot forming.And in the production process of Laser Processing, at first,, utilize CAM to create cutting path based on the drawing of design support.Secondly, metal or macromolecular material are carried out cut.
After being laser-cut into shape of a mesh, use electrobrightening to improve surface smoothness, make each edge shape mellow and full.In the manufacturing process of cochrome support, the post processing after the cut is an important engineering.Support after the cut, at first the metal with oxidation dissolves in acid solution, carries out electrobrightening afterwards.For accomplishing the end in view, the condition that is necessary to consider the composition of electrolyte and applies electric current.
[embodiment]
Below, through example invention being described, invention is not limited only to following examples.Following examples, as expansion pressure relatively, bending fatigue strength, pliability, axially cripetura rate, rebound degree radially, maximum distortion etc.Measure by following method.
(expansion pressure)
With the support of 3.0 mm dias, insert internal diameter 3.0mm, external diameter is the silica gel tube of 4.0mm, injects normal saline, when shelf inner diameter reaches 3mm, the balloon dilatation pressure of mensuration.
(bending fatigue strength)
The fixed support two ends, shown in figure 11, the left side is fixed, and the right side connects cam, and cam through the promotion of cam, is realized the bending that carriage center partly produces off-center 2.0mm by motor-driven, repeats above operation, until the support fracture, and writing time.
(pliability)
The four-point bending test method is measured bending stiffness, the assessment pliability.
(axially cripetura rate)
With support, insert internal diameter 3.0mm, external diameter is the silica gel tube of 4.0mm, injects normal saline, shelf inner diameter reaches 3mm.Expansion back measurement bracket length compares with expansion fore-stock length, calculates the cripetura rate, is axial cripetura rate.
(radially resilience)
With support, insert internal diameter 3.0mm, external diameter is the silica gel tube of 4.0mm, injects normal saline, utilizes sacculus that support is expanded to after the internal diameter 3mm, the unloading sacculus is measured the internal diameter varies rate before and after unloading, and is radially rebound degree.
(maximum strain measurement)
For the angle from the strength of materials is estimated the distortion that each position of support takes place; Support held from pressure behind balloon expandable, keep somewhere endovascular whole process; Set up the FEM model of support; Import corresponding material behavior, utilize computer to carry out simulation analysis, contrasted maximum stress.
Support of the present invention (embodiment 1) is compared with following Comparative Examples 1-3, comparative result is depicted as chart such as table 1 and shown in Figure 12.Embodiment 1 all adopts length 17.4mm with Comparative Examples, diameter 1.0mm during contraction, during expansion during internal diameter 3.0mm, U-shaped support 2,2 ' the part of junction point 4 be of a size of definite value: width 100 μ, thickness 80 μ process by cochrome.
(embodiment 1)
Radius of curvature R 0.15 μ of straightway tangent arc, the radius of curvature on circular arc arc top (participating in connecting) is got 1.3 times of tangent arc, i.e. R0.20 μ (like Fig. 2).
(Comparative Examples 1)
As shown in Figure 7, Comparative Examples is a conventional stent, and a plurality of one type of U-shaped support 11 circumferential arrangement form one type of annular unit 12 and two types of two types of annular units 12 ' alternate configurations, formation support tubular bodies that the U-shaped support is formed.Adjacent annular unit all connects through coupling part 14, has the ability of being upheld by inside.
(Comparative Examples 2)
As shown in Figure 5, radius of curvature R 0.15 μ at the top 10 of circular arc, the length 1.2mm of a U-shaped support, the number that comprises the U-shaped support among coupling part length: the 1.3mm, annular unit is 6.
(Comparative Examples 3)
As shown in Figure 3, radius of curvature R 0.15 μ at the top 10 of circular arc, the length 1.2mm of a U-shaped support, the number that comprises the U-shaped support among coupling part length: the 1.3mm, annular unit is 6.Other physical dimension is identical with embodiment.
As shown in table 1, the experimental result demonstration connects support (Comparative Examples 1) entirely and partly being connected support compares (embodiment 1, Comparative Examples 2,3), and the fatigue strength that partly connects support is preferable.Its reason, part connects support, its structure can form 3 D deformation (obligatory point is few, and degree of freedom is high), reduce at the actual load at junction point place, relatively be connected support entirely, crooked deformability is improved.Connect in the support in part, the support of embodiment 1, edurance beding strength is superior to other structure.Its reason is embodiment 1 by bending during load, maximum distortion lower (seeing Figure 12), thus having reduced the suffered load of U-shaped support, bending fatigue strength is improved.In addition, the standard of embodiment 1 expansion is pressed and is 8atm, and Comparative Examples 2 is pressed with 3 standard expansion and is 9atm, shows to expand uniformity and flexibility is superior to other.This support is suitable basically with conventional stent aspect axial cripetura and resilience radially, and fatigue strength and each item performance show superior.
Table 1 testing experiment result
This support at first makes every effort to reduce maximum stress and distortion as far as possible, secondly, makes the arc sections of U-shaped support as far as possible, the stress that line part and connecting portion branch bear, and strain facies is worked as.Shown in Figure 2 is arc section 5 and the partial enlarged drawing of coupling part 4 of the U-shaped support of embodiment 1.The present invention provides as shown in the figure, has good fatigue strength, and when bearing bending load, and structure can homogeneous deformation, the stress of arc sections 5 and coupling part 4, the essentially identical support of strain.
As stated, support of the present invention, the arc section 5 of U-shaped support, coupling part 4 and the flection part of the U-shaped support of Comparative Examples 1 and the arc section 10 of Comparative Examples 2,3, coupling part 9 is compared, and has the structure of bearing lower stress and strain.Simultaneously; For reducing maximum stress and the strain that junction point 4 places produce; The radius of curvature on the arc of the arc section 5 that is adopted top is 1.1～1.5 a structure of the radius of curvature of straightway and arc section tangent arc, makes bending fatigue strength be improved, pliability with expand uniformity and all improve.
The present invention provides a supporting structure with high bending fatigue strength and motility, helps the development of support manufacturing technology, and the industry contribution is very big, and the probability of industry application is very big.In addition, support of the present invention, it can utilize the Laser Processing manufacturing, so the industrialization manufacturing feasibility is very big.
Claims (10)
1. coronary artery bracket; It is axially alternately to arrange successively by one type of annular unit and two types of annular units and forms the tubular body structure; Said tubular body structure has the support of expansible performance along radial direction; Said one type of annular unit and said two types of annular units all are annular units that the U-shaped support serial connection an end opening in axial direction is formed by connecting, and the opening direction of the U-shaped mouth of the adjacent U-shaped support of said annular unit is rightabout, and said U-shaped support is made up of straightway and arc section; It is characterized in that
Part in the adjacent corresponding circle segmental arc of the U-shaped support of said one type of annular unit and the U-shaped support of said two types of annular units connects with corresponding connection circular arc.
2. a kind of coronary artery bracket according to claim 1 is characterized in that, the number of the U-shaped support of said two types of annular units be said one type of annular unit the U-shaped support number 1.4-1.6 doubly.
3. a kind of coronary artery bracket according to claim 1 is characterized in that, the length of straigh line of the U-shaped support of said one type of annular unit be said two types of annular units U-shaped support length of straigh line 1.4-1.6 doubly.
4. a kind of coronary artery bracket according to claim 1; It is characterized in that the radius of curvature of the arc section arc top portion of each U-shaped support that said one type of annular unit is connected with said two types of annular units participation has neither part nor lot in the radius of curvature of each the U-shaped support arc section that is connected greater than said one type of annular unit and said two types of annular units.
5. a kind of coronary artery bracket according to claim 4; It is characterized in that; The radius of curvature of the arc section arc top portion of each U-shaped support that said one type of annular unit and said two types of annular units participate in being connected is said one type of annular unit has neither part nor lot in 1.1-1.5 times of radius of curvature of each the U-shaped support arc section that is connected with said two types of annular units.
6. a kind of coronary artery bracket according to claim 1; It is characterized in that, the width of the straightway of each the U-shaped support in said one type of annular unit and the said two types of annular units be have neither part nor lot in each the U-shaped support arc section that is connected width 1.1-1.5 doubly.
7. a kind of coronary artery bracket according to claim 6; It is characterized in that; The length of straigh line of each U-shaped support that said one type of annular unit and said two types of annular units participate in being connected has neither part nor lot in the long 10-25% of length of straightway of each U-shaped support of said one type of annular unit and said two types of annular units of connection relatively.
8. a kind of coronary artery bracket according to claim 1 is characterized in that, each said one type of annular unit is made up of 6-10 U type support.
9. a kind of coronary artery bracket according to claim 1; It is characterized in that the U-shaped support of said one type of annular unit and the U-shaped support of said two types of annular units are tangent connections of center circular arc through the U-shaped support of the center circular arc of the U-shaped support of said one type of annular unit and said two types of annular units.
10. a method of making each described coronary artery bracket of claim 1-9 is characterized in that, may further comprise the steps:
At first, according to the structure of design support, utilize CAM to create cutting path;
Secondly, metal or macromolecular material are carried out cut, by being laser-cut into shape of a mesh;
At last, with the support after the cut, the metal with oxidation dissolves in acid solution earlier, carries out electrobrightening afterwards, makes each edge shape mellow and full.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210141095XA CN102813566A (en) | 2012-04-24 | 2012-04-24 | Coronary stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210141095XA CN102813566A (en) | 2012-04-24 | 2012-04-24 | Coronary stent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102813566A true CN102813566A (en) | 2012-12-12 |
Family
ID=47298261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210141095XA Pending CN102813566A (en) | 2012-04-24 | 2012-04-24 | Coronary stent |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102813566A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106691647A (en) * | 2015-07-20 | 2017-05-24 | 上海交通大学 | Biodegradable metal intravascular stent and application thereof |
| CN107550611A (en) * | 2017-10-18 | 2018-01-09 | 科塞尔医疗科技（苏州）有限公司 | A kind of intravascular stent |
| CN110742709A (en) * | 2016-03-18 | 2020-02-04 | 杭州唯强医疗科技有限公司 | Aorta bare stent and aorta interlayer stent |
| CN113456290A (en) * | 2021-06-24 | 2021-10-01 | 北京科技大学 | Degradable metal skull repairing mesh implant |
| CN113545898A (en) * | 2021-08-31 | 2021-10-26 | 西北有色金属研究院 | Vascular stent structure with uniform stress |
| CN116672021A (en) * | 2022-05-06 | 2023-09-01 | 上海励楷科技有限公司 | Support frame |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000008187A (en) * | 1998-06-25 | 2000-01-11 | Oudenshiya:Kk | Stent and its manufacture |
| WO2008126894A1 (en) * | 2007-04-12 | 2008-10-23 | Kaneka Corporation | Stent |
| CN201572353U (en) * | 2009-05-15 | 2010-09-08 | 先健科技(深圳)有限公司 | Human body absorbable intravascular stent |
| WO2011034154A1 (en) * | 2009-09-17 | 2011-03-24 | 株式会社日本ステントテクノロジー | Stent |
| CN202568545U (en) * | 2012-02-01 | 2012-12-05 | 内蒙古工业大学 | Coronary stent |
-
2012
- 2012-04-24 CN CN201210141095XA patent/CN102813566A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000008187A (en) * | 1998-06-25 | 2000-01-11 | Oudenshiya:Kk | Stent and its manufacture |
| WO2008126894A1 (en) * | 2007-04-12 | 2008-10-23 | Kaneka Corporation | Stent |
| CN201572353U (en) * | 2009-05-15 | 2010-09-08 | 先健科技(深圳)有限公司 | Human body absorbable intravascular stent |
| WO2011034154A1 (en) * | 2009-09-17 | 2011-03-24 | 株式会社日本ステントテクノロジー | Stent |
| CN202568545U (en) * | 2012-02-01 | 2012-12-05 | 内蒙古工业大学 | Coronary stent |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106691647A (en) * | 2015-07-20 | 2017-05-24 | 上海交通大学 | Biodegradable metal intravascular stent and application thereof |
| CN106691647B (en) * | 2015-07-20 | 2019-05-24 | 上海交通大学 | A kind of biodegradable metals intravascular stent and its application |
| CN110742709A (en) * | 2016-03-18 | 2020-02-04 | 杭州唯强医疗科技有限公司 | Aorta bare stent and aorta interlayer stent |
| CN107550611A (en) * | 2017-10-18 | 2018-01-09 | 科塞尔医疗科技（苏州）有限公司 | A kind of intravascular stent |
| CN107550611B (en) * | 2017-10-18 | 2024-03-15 | 科塞尔医疗科技（苏州）有限公司 | Vascular stent |
| CN113456290A (en) * | 2021-06-24 | 2021-10-01 | 北京科技大学 | Degradable metal skull repairing mesh implant |
| CN113545898A (en) * | 2021-08-31 | 2021-10-26 | 西北有色金属研究院 | Vascular stent structure with uniform stress |
| CN116672021A (en) * | 2022-05-06 | 2023-09-01 | 上海励楷科技有限公司 | Support frame |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102813566A (en) | Coronary stent | |
| KR101019896B1 (en) | Flexible and conformable stent and method of forming same | |
| CA2211097C (en) | Stent with variable features to optimize support and method of making such stent | |
| CN204951247U (en) | Biodegradable metal blood vessel support | |
| JP2015226830A (en) | Implants having high fatigue resistance, implant delivery systems, and methods of use | |
| CN105726174B (en) | A kind of intravascular stent, preparation method and application | |
| JP2001259041A (en) | Stent flexible in longitudinal direction | |
| JP2009528112A (en) | Stent with deformable shape to optimize support and method of making the stent | |
| CN106691647B (en) | A kind of biodegradable metals intravascular stent and its application | |
| CN103300951A (en) | Vertebral artery stent | |
| CN213641427U (en) | Degradable metal magnesium blood vessel stent | |
| CN202568545U (en) | Coronary stent | |
| CN108670510A (en) | A kind of intracranial vessel holder that compliance is excellent | |
| CN106361478A (en) | Mixed saccule expansion type vascular stent | |
| CN105726178B (en) | A kind of intravascular stent, its preparation method and application | |
| CN203425070U (en) | Vertebral artery stent | |
| CN106176003A (en) | A kind of intravascular stent, its preparation method and application | |
| CN103110465B (en) | Magnesium alloy coronary support frame | |
| US8192483B2 (en) | Stent to be placed in the living body | |
| CN111374809B (en) | Vertebral artery stent | |
| US11471309B2 (en) | Intravascular stent, preparation method and use thereof | |
| CN201350139Y (en) | Coronary artery balloon expandable stent with high radial bracing force | |
| CN110234300A (en) | Biological absorbable support | |
| CN207168613U (en) | A kind of intravascular stent | |
| CN107550611A (en) | A kind of intravascular stent |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C05 | Deemed withdrawal (patent law before 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20121212 |