CN1075380C - Medicine for enuresis and its preparation - Google Patents
Medicine for enuresis and its preparation Download PDFInfo
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- CN1075380C CN1075380C CN98125191A CN98125191A CN1075380C CN 1075380 C CN1075380 C CN 1075380C CN 98125191 A CN98125191 A CN 98125191A CN 98125191 A CN98125191 A CN 98125191A CN 1075380 C CN1075380 C CN 1075380C
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- enuresis
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Abstract
The present invention discloses new medicine for treating enuresis, which is mainly used for treating the enuresis caused by various reasons. The new medicine for treating enuresis is a preparation of pure Chinese medicine, and is proportionally prepared from ginseng, thinleaf milkwort root, semen amomi amari, sauted combined spicebush root, ootheca mantidis, calamus, forging fossilia ossis mastodi, sauted yam, dodder seed, raspberry, allium tuberosum, ginkgo and ventriculi galli mucosa which are used as materials; various preparations, such as watered pills, etc., can be prepared by processing according to the property of each kind of medicine. The present invention has the advantages of unique prescriptions and preparation method and conspicuous curative effect, and the present invention can treat both manifestation and root cause of disease.
Description
The present invention relates to a kind of medicine for the treatment of enuresis, specifically a kind of is the pure Chinese medicinal preparation of the treatment enuresis made of raw material with the natural Chinese medicinal herb, the invention still further relates to the preparation method of this medicine.
Enuresis is a kind of common disease, influences patient's physical and mental health and daily life, and is especially in the majority with adolescent patient.The enuresis is a kind of cardinal symptom of enuresis, causes that this sick cause of disease is a lot, and it is not only relevant with nervous system, but also involves endocrine and urinary system.The cardinal symptom of enuresis is not cry when sleeping to wake up, and it is seized with terror to talk in sleep after having cried out, and Chang Dongzhuan changes in the west, grabs body and scratches one's head and be at a loss, and frequent micturition, urgent micturition, bladder are little, frequent urination at night etc.Older patient easily has inferiority complex, directly influence life and study.This disease sickness rate height, and enuresis family history is arranged more.Existing this sick medicine of treatment exists many-sided deficiency, and effect is all unsatisfactory.Use Western medicine as " Meclofenoxate " treatment normally by improving the nerve centre irritability, reach the purpose of temporarily not wetting the bed to shrink sphincter vesicae, diastole wall of urinary bladder.But tend to the influence sleep, and certain side effect is arranged and be difficult to reach radical cure.Existing herbal treatment therapeutic effect is generally also unsatisfactory.
The object of the present invention is to provide the pure Chinese drugs agentia of the enuresis that a kind of treatment causes by Different types of etiopathogenises, based on brain-strengthening, reducing urination is auxilliary, not only can eliminate its various symptoms quickly, and can improve patient's diet, sleep and the mental status preferably, raising is coordinated urinary function to the respond of surrounding, reaches the effect of effecting a permanent cure.Instant effect, curative effect height, toxic and side effects are low, and are difficult for recurrence.
Another object of the present invention provides the preparation method of this enuresis therapeutic agent.
Solution of the present invention is based on pathogenetic understanding and the Therapeutic Principle of motherland's medical science to enuresis, with reference to the modern pharmacological research achievement, from motherland's medicine treasure-house, filter out brain-tonifying and kidney-nourishing, promotion ideas-straightening, Gu the natural drug of bladder reducing urination is according to the theory of Chinese medical science prescription.Each medicine synergism of distinguishing the flavor of is to reach curative effect.
The present invention treats the medicine of enuresis and is made by following component: (consumption is a weight portion)
Radix Ginseng 10-15 Radix Polygalae 17-25 Fructus Alpiniae Oxyphyllae 27-34
Fry Radix Linderae 15-23 Ootheca Mantidis 24-37 Rhizoma Acori Graminei 16-27
Forge Os Draconis 19-28 Rhizoma dioscoreae (parched) 11-29 Semen Cuscutae 13-25
Fructus Rubi 15-25 Semen Allii Tuberosi 10-22 Semen Ginkgo 5-14
Endothelium Corneum Gigeriae Galli 17-26
Formula optimization weight (part) ratio range of preparation medicine of the present invention is:
Radix Ginseng 12 Radix Polygalaes 20 Fructus Alpiniae Oxyphyllae 30
Fry the Radix Linderae 20 Ootheca Mantidiss 30 Rhizoma Acori Gramineis 20
Forge Os Draconis 20 Rhizoma dioscoreae (parched)s 20 Semen Cuscutae 20
Fructus Rubi 20 Semen Allii Tuberosi 18 Semen Ginkgoes 12
Endothelium Corneum Gigeriae Galli 20
Each flavor is crude drug in the medicine of the present invention, but warming and recuperating the kidney-YANG, the refreshment of having one's ideas straightened out, tranquilizing the mind make that kidney qi is abundant, astringency inducing is had the right, and bladder is gasified and retrains; Make simultaneously the astringent or styptic treatment for spontaneous sweating medicine of kidney tonifying in addition, end with solid bladder and losing.Principal agent is that Radix Ginseng, Fructus Alpiniae Oxyphyllae, Rhizoma Acori Graminei, Ootheca Mantidis and Radix Polygalae are principal agent, and it act as kidney-tonifying and brain tonic, reducing urination, and having one's ideas straightened out increases intelligence and calms the nerves etc.All the other medicines of respectively distinguishing the flavor of are accessory drugs, act as QI invigorating, restrain astringent or styptic treatment for spontaneous sweating, Gu bladder end to be lost.All medicines cooperate can make the spirit of patient's brains, and it is big that bladder becomes, and urine is suppressed and can be waken up, and makes the enuresis from ending.Then enuresis spontaneous recovery after urinary function is coordinated.
Medicine of the present invention can be made various dosage forms according to a conventional method.Preferred water pill-type wherein.
The watered pill preparation method is a conventional method.Can be made into the watered pill of Semen phaseoli radiati size.
For showing the therapeutic effect of medicine of the present invention to enuresis, systematically select all ages and classes, sex and dissimilar enuresis cases, comprised simple heritability enuresis, cryptomerorachischisis enuresis, meninges bulging sequela enuresis and four types of the enuresis that cause by cerebrovascular accident.Clinical symptoms is: nocturia often, and is especially more in winter or tired back number of times; Diet is few; Urinate often, and frequent micturition, urgent micturition phenomenon are arranged; Deficiency of kidney-QI, bladder is less, and urine can not be waken up when suppressing; The night sweat phenomenon is easily arranged in bed.Use medicine of the present invention to treat, be 30 days a course of treatment.
Instructions of taking: the dose of taking is decided according to different age brackets, a twice-daily.The dosage form of taking is the watered pill.
Every days 15 gram 6-8 year every days 10 in 4-5 year gram
Every days 22.5 gram 13-14 year every days 20 in 8-12 year gram
Every days 25 in 15-16 year gram more than 16 years old every days 30 gram
Treatment cycle is a course of treatment.
Its therapeutic effect can be added up referring to table 1 to table 4 curative effect clinical data.
From the identical patient of symptom, select 50 examples in addition, adopt the Meclofenoxate treatment, in contrast group, consumption is each 0.1 gram, every day three times, be 30 days a course of treatment, and its therapeutic effect is referring to table 5 curative effect clinical data statistics (wherein effective percentage is produce effects and effective percentage sum).
Recovery from illness: the bed-wetting phenomenon disappears, it is normal that clinical symptoms (diet, sleep, the mental status, complexion, urine number of times, perspiration and pulse condition) is recovered, immune globulin Pseudobulbus Bletillae (Rhizoma Bletillae) trace element improves, and respond, understandability and the resistance against diseases of surrounding all had bigger improvement;
Produce effects: IQ improves more than 10, has more than 5 in the clinical symptoms (diet, sleep, the mental status, complexion, urine number of times, perspiration and pulse condition) to improve, and the respond that self care ability reaches surrounding is strengthened;
Effectively: IQ improves 5-10, improves more than in the clinical symptoms (diet, sleep, the mental status, complexion, urine number of times, perspiration and pulse condition) the 3-5 item being arranged, and the respond of surrounding is increased;
Invalid: symptom does not have obvious improvement.
The clinical data statistics of the simple heritability enuresis treatment of table 1
| Age (year) | Case load (people) | Recovery from illness | Produce effects | Effectively | Invalid |
| 4-5 | 1826 | 1187 | 14 | 4 | 0 |
| 6-14 | 13693 | 12343 | 24 | 17 | 2 |
| More than 15 years old | 1321 | 953 | 18 | 20 | 1 |
| Effective percentage 86% 11% 3% 0% | |||||
The clinical data statistics of table 2 cryptomerorachischisis enuresis treatment
| Age (year) | Case load (people) | Recovery from illness | Produce effects | Effectively | Invalid |
| 4-5 | 1403 | 972 | 352 | 43 | 36 |
| 6-14 | 2277 | 1753 | 347 | 177 | 0 |
| More than 15 years old | 632 | 547 | 54 | 55 | 16 |
| Effective percentage 76% 17% 6% 1% | |||||
The clinical data statistics of table 3 meninges bulging sequela enuresis treatment
| Age (year) | Case load (people) | Recovery from illness | Produce effects | Effectively | Invalid |
| 4-5 | 50 | 29 | 13 | 6 | 2 |
| 6-14 | 99 | 73 | 17 | 9 | 0 |
| More than 15 years old | 36 | 24 | 5 | 4 | 3 |
| Effective percentage 68% 19.3% 10.2% 2.5% | |||||
The clinical data statistics of table 4 cerebrovascular accident enuresis treatment
| Age (year) | Case load | Recovery from illness | Produce effects | Effectively | Invalid |
| (people) | |||||
| 4-5 | 115 | 74 | 24 | 17 | 4 |
| 6-14 | 179 | 113 | 31 | 33 | 2 |
| More than 15 years old | 47 | 12 | 19 | 7 | 7 |
| Effective percentage 58% 21.5% 16% 4.5% | |||||
The clinical data statistics of table 5 enuresis treatment of control group
| Recovery from illness | Effectively | Invalid | |
| Case load (people) | 17 | 18 | 15 |
| Effective percentage | 34％ | 36％ | 30％ |
By above-mentioned clinical data as seen, medicine of the present invention all has for the enuresis that is caused by multiple reason and better obtains curative effect, and is especially good especially for the therapeutic effect of simple heritability enuresis, treating both the principal and secondary aspects of a disease.Make enuresis spontaneous recovery by regulating and strengthening patient self function.Not only can eliminate and alleviate the symptom of enuresis quickly, can improve patient's diet, sleep and the mental status preferably simultaneously, improve respond, coordinate urinary function, reach the effect of effecting a permanent cure surrounding.Therapeutic effect has stability, certainty.Taking convenience, patient easily accepts, and side effect is little.
Embodiment
Take by weighing raw material (kilogram) by following proportioning:
Radix Ginseng 12 Radix Polygalaes 20 Fructus Alpiniae Oxyphyllae 30
Fry the Radix Linderae 20 Ootheca Mantidiss 30 Rhizoma Acori Gramineis 20
Forge Os Draconis 20 Rhizoma dioscoreae (parched)s 20 Semen Cuscutae 20
Fructus Rubi 20 Semen Allii Tuberosi 18 Semen Ginkgoes 12
Endothelium Corneum Gigeriae Galli 20
Watered pill preparation method:
Behind above-mentioned medical material oven dry, pulverizing and mixing, cross 1000 mesh sieves, sterilization is made the watered pill with pellet processing machine and is got final product.
Model case:
1. the hole is peaceful, the man, and 15 years old, Shangcai County, Henan Province hundred chis rurally closed three groups of people.In 1997
Come to go to a doctor on October 6, in.It is heavier by one in the heritability enuresis that this patient belongs to
Class, promptly its parents once suffered from this disease, did not have other diseases on inspection.This patient is nocturia every night
1-2 time, there are frequent micturition, urgent micturition phenomenon to be difficult in bed waking evening, it is seized with terror to talk in sleep after waking up,
Therefore ridiculed by household and other people, introverted, feel oneself inferior, school grade descends.
Just do not wet the bed after 12 days through taking medicine of the present invention, the urine of initiatively getting up night is waken easily, and self care ability improves, and fully recovers after 18 days through after treatment.2. Yang Qing force, man, 10 years old, east, Puyang County Qing Hetou township Sapporo dress people from village.On August 13rd, 1998 came to go to a doctor.This patient once suffered from the nervous bladder inflammation in the time of 14 years old, occur after the underwent operative wetting the bed, and do X-ray examination cryptomerorachischisis was arranged.After taking surplus the medicine 20 of the present invention day, can initiatively get up urine and do not wet the bed night, and after treatment is fully recovered after a couple of days.3. the little guiding principle of Xu, the man, 11 years old, Jiang Dian township, Wuyang County, Henan Province Xu Cun people in the Meng come to go to a doctor on April 22nd, 1996.1 years old half of this patient done operation because of suffering from the meninges bulging, occurred enuresis phenomenon after the operation, and bladder is little, frequent micturition.Promptly do not wet the bed after 6 days through taking Drug therapy of the present invention, and do not have urine night, walking has also relieved oneself than crossing.4. the auspicious crane in hole, the man 72 years old, lives 127 2 of Kuituns, Xinjiang and connects its bride's side.Went to a doctor on March 18th, 1997, this patient causes the enuresis in August, 1996 after suffering from cerebral thrombosis, and nocturia is 4-5 time every night, and bladder is little, frequent micturition, but daytime anuria trousers phenomenon.Through take medicine of the present invention after 23 days the enuresis stop, after treatment is fully recovered after a couple of days.
Claims (4)
1. medicine for the treatment of enuresis is characterized in that it is the medicament of being made by the following weight proportion raw material:
Radix Ginseng 10-15 Radix Polygalae 17-25 Fructus Alpiniae Oxyphyllae 27-34
Fry Radix Linderae 15-23 Ootheca Mantidis 24-37 Rhizoma Acori Graminei 16-27
Forge Os Draconis 19-28 Rhizoma dioscoreae (parched) 11-29 Semen Cuscutae 13-25
Fructus Rubi 15-25 Semen Allii Tuberosi 10-22 Semen Ginkgo 5-14
Endothelium Corneum Gigeriae Galli 17-26.
2. the medicine of treatment enuresis according to claim 1, wherein the weight proportion of each raw material is:
Radix Ginseng 12 Radix Polygalaes 20 Fructus Alpiniae Oxyphyllae 30
Fry the Radix Linderae 20 Ootheca Mantidiss 30 Rhizoma Acori Gramineis 20
Forge Os Draconis 20 Rhizoma dioscoreae (parched)s 20 Semen Cuscutae 20
Fructus Rubi 20 Semen Allii Tuberosi 18 Semen Ginkgoes 12
Endothelium Corneum Gigeriae Galli 20.
3. the medicine of treatment enuresis according to claim 1 and 2 is characterized in that said medicament is a said dosage form on any pharmaceutics.
4. the medicine of treatment enuresis disease according to claim 3 is characterized in that said medicament is a watered pill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98125191A CN1075380C (en) | 1998-12-08 | 1998-12-08 | Medicine for enuresis and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98125191A CN1075380C (en) | 1998-12-08 | 1998-12-08 | Medicine for enuresis and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1256132A CN1256132A (en) | 2000-06-14 |
| CN1075380C true CN1075380C (en) | 2001-11-28 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98125191A Expired - Lifetime CN1075380C (en) | 1998-12-08 | 1998-12-08 | Medicine for enuresis and its preparation |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100450531C (en) * | 2006-11-15 | 2009-01-14 | 北京万寿通医药科技有限公司 | Chinese medicinal formulation for treating infant bed wetting |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142813A (en) * | 2013-04-01 | 2013-06-12 | 上海浦东高星生物技术研究所 | Semen-consolidating spermatorrhea-controlling pill |
| CN109498773A (en) * | 2018-12-26 | 2019-03-22 | 阜新蒙古族自治县蒙医医院 | A kind of anaesthetic of kidney tonifying and preparation method thereof |
| CN109876065A (en) * | 2019-04-19 | 2019-06-14 | 薛振宇 | A kind of formula and preparation method thereof for treating urinary disease |
| CN112641911A (en) * | 2019-10-10 | 2021-04-13 | 王忠民 | Medicine for quickly treating enuresis and premature ejaculation |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1081891A (en) * | 1993-02-18 | 1994-02-16 | 贺哲 | Quick-acting powder to cure enuresis |
| CN1129589A (en) * | 1995-12-05 | 1996-08-28 | 吴进禄 | Medicine for curing enuresis |
-
1998
- 1998-12-08 CN CN98125191A patent/CN1075380C/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1081891A (en) * | 1993-02-18 | 1994-02-16 | 贺哲 | Quick-acting powder to cure enuresis |
| CN1129589A (en) * | 1995-12-05 | 1996-08-28 | 吴进禄 | Medicine for curing enuresis |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100450531C (en) * | 2006-11-15 | 2009-01-14 | 北京万寿通医药科技有限公司 | Chinese medicinal formulation for treating infant bed wetting |
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| Publication number | Publication date |
|---|---|
| CN1256132A (en) | 2000-06-14 |
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