CN107533052B - 在免疫测定中重复使用测试探针和试剂的方法 - Google Patents

在免疫测定中重复使用测试探针和试剂的方法 Download PDF

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Publication number
CN107533052B
CN107533052B CN201680027104.9A CN201680027104A CN107533052B CN 107533052 B CN107533052 B CN 107533052B CN 201680027104 A CN201680027104 A CN 201680027104A CN 107533052 B CN107533052 B CN 107533052B
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probe
antibody
sample
probe tip
reagent
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CN107533052A (zh
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罗伯特·F·祖克
夏青
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Access Medical Systems Ltd
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Access Medical Systems Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4737—C-reactive protein

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN201680027104.9A 2015-05-11 2016-05-10 在免疫测定中重复使用测试探针和试剂的方法 Active CN107533052B (zh)

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Application Number Priority Date Filing Date Title
US201562159919P 2015-05-11 2015-05-11
US62/159,919 2015-05-11
PCT/US2016/031661 WO2016183092A1 (en) 2015-05-11 2016-05-10 Method for re-using test probe and reagents in an immunoassay

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CN107533052A CN107533052A (zh) 2018-01-02
CN107533052B true CN107533052B (zh) 2023-04-28

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US (2) US20180128826A1 (enExample)
EP (1) EP3295174B1 (enExample)
JP (1) JP6810055B2 (enExample)
CN (1) CN107533052B (enExample)
CA (1) CA2985073A1 (enExample)
WO (1) WO2016183092A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110023756B (zh) * 2016-10-31 2023-06-30 万迈医疗仪器有限公司 基于干涉测量在免疫测定中重复使用测试探针和试剂的方法
CN113710365B (zh) * 2019-04-03 2023-12-19 万迈医疗仪器有限公司 用于在免疫测定中重复使用半抗原涂覆的探针的方法
CN110632329B (zh) * 2019-10-25 2024-11-15 东北师范大学 一种便携式铅笔型免疫传感器及应用
US20240302386A1 (en) * 2020-12-23 2024-09-12 Access Medical Systems, Ltd. Detection method using both fluorescence and chemiluminescence labels
CN114994302B (zh) * 2022-06-09 2024-11-22 星童医疗技术(苏州)有限公司 免疫类体外诊断试剂检测结果有效性确定方法及系统
JPWO2024101447A1 (enExample) * 2022-11-11 2024-05-16
CN117368495B (zh) * 2023-10-26 2024-08-09 星童医疗技术(苏州)有限公司 人绒毛膜促性腺激素β亚单位含量检测方法及试剂盒

Citations (4)

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CN1700009A (zh) * 2005-05-30 2005-11-23 孙东旭 用单一捕获剂定量检测特异性分析物的方法及其试剂盒
CN102341696A (zh) * 2009-03-03 2012-02-01 万迈医疗仪器有限公司 用于高灵敏度荧光分析的检测系统和方法
CN103430024A (zh) * 2011-01-08 2013-12-04 万迈医疗仪器有限公司 用于免疫分析检测的系统
CN104246500A (zh) * 2012-04-16 2014-12-24 万迈医疗仪器有限公司 宽范围发光免疫分析

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WO1988005538A1 (en) * 1987-01-15 1988-07-28 Hevey Richard C Method of detecting and quantifying ligands in liquids
US4863876A (en) * 1987-01-15 1989-09-05 Hevey Richard C Method of detecting and quantifying ligands in liquids via biotin-avidin-medicated fluorescence polarization
JP3005400B2 (ja) * 1993-09-16 2000-01-31 株式会社トクヤマ 抗原または抗体濃度の測定方法
US5650334A (en) 1995-08-31 1997-07-22 First Medical, Inc. Fluorescent labelling compositions and methods for their use
WO1998009156A1 (en) * 1996-08-29 1998-03-05 Novartis Ag Optical chemical / biochemical sensor
US6289286B1 (en) * 1998-05-29 2001-09-11 Biacore Ab Surface regeneration of biosensors and characterization of biomolecules associated therewith
US8354280B2 (en) * 2007-09-06 2013-01-15 Bioscale, Inc. Reusable detection surfaces and methods of using same
CN102326068B (zh) * 2009-02-20 2015-04-08 万迈医疗仪器有限公司 一种用于在样品中基于薄膜频谱干涉检测被分析物的组件
WO2012145270A2 (en) 2011-04-20 2012-10-26 Access Medical Systems, Ltd. Luminescent polymer cyclic amplification

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CN1700009A (zh) * 2005-05-30 2005-11-23 孙东旭 用单一捕获剂定量检测特异性分析物的方法及其试剂盒
CN102341696A (zh) * 2009-03-03 2012-02-01 万迈医疗仪器有限公司 用于高灵敏度荧光分析的检测系统和方法
CN103430024A (zh) * 2011-01-08 2013-12-04 万迈医疗仪器有限公司 用于免疫分析检测的系统
CN104246500A (zh) * 2012-04-16 2014-12-24 万迈医疗仪器有限公司 宽范围发光免疫分析

Non-Patent Citations (1)

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Regeneration of immobilized antibodies on fiber optic probes;Daya Wijesuriya et al.;《Biosensors & Bioelectronics》;19941231;第9卷;摘要，587页右栏-588页右栏，589-590页讨论部分，图1-2 *

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Publication number Publication date
EP3295174B1 (en) 2020-11-04
WO2016183092A1 (en) 2016-11-17
JP6810055B2 (ja) 2021-01-06
EP3295174A1 (en) 2018-03-21
JP2018522214A (ja) 2018-08-09
US20180128826A1 (en) 2018-05-10
EP3295174A4 (en) 2019-03-20
CN107533052A (zh) 2018-01-02
CA2985073A1 (en) 2016-11-17
US20200333337A1 (en) 2020-10-22

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