CN107532181A - Mirna模拟物和它们在治疗感觉病患中的用途 - Google Patents
Mirna模拟物和它们在治疗感觉病患中的用途 Download PDFInfo
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- CN107532181A CN107532181A CN201680026725.5A CN201680026725A CN107532181A CN 107532181 A CN107532181 A CN 107532181A CN 201680026725 A CN201680026725 A CN 201680026725A CN 107532181 A CN107532181 A CN 107532181A
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- microrna
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Classifications
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A61P27/00—Drugs for disorders of the senses
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562133590P | 2015-03-16 | 2015-03-16 | |
| US62/133,590 | 2015-03-16 | ||
| PCT/US2016/022645 WO2016149370A1 (en) | 2015-03-16 | 2016-03-16 | Mirna mimetics and their use in treating sensory conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107532181A true CN107532181A (zh) | 2018-01-02 |
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| CN201680026725.5A Pending CN107532181A (zh) | 2015-03-16 | 2016-03-16 | Mirna模拟物和它们在治疗感觉病患中的用途 |
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| US (1) | US20180080023A1 (enExample) |
| EP (1) | EP3271464A4 (enExample) |
| JP (1) | JP2018509912A (enExample) |
| CN (1) | CN107532181A (enExample) |
| AU (1) | AU2016233311A1 (enExample) |
| CA (1) | CA2979825A1 (enExample) |
| WO (1) | WO2016149370A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110013486A (zh) * | 2019-03-27 | 2019-07-16 | 浙江大学 | mmu-miR-183-5p在制备抑制胚胎着床的药物中的应用 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019195765A1 (en) | 2018-04-06 | 2019-10-10 | University Of Massachusetts | Mlk-regulated micrornas in angiogenesis and tumor development |
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| WO2009137807A2 (en) * | 2008-05-08 | 2009-11-12 | Asuragen, Inc. | Compositions and methods related to mirna modulation of neovascularization or angiogenesis |
| CN101842381A (zh) * | 2007-08-27 | 2010-09-22 | 波士顿生物医药公司 | 作为微小rna模拟物或抑制剂的不对称rna双链体的组合物 |
| US20130225652A1 (en) * | 2009-08-24 | 2013-08-29 | Guillaume Chorn | Segmented micro rna mimetics |
| WO2014100252A1 (en) * | 2012-12-18 | 2014-06-26 | University Of Washington Through Its Center For Commercialization | Methods and compositions to modulate rna processing |
| US20150051267A1 (en) * | 2013-08-16 | 2015-02-19 | Purdue Research Foundation | BICISTRONIC GENE TRANSFER TOOLS FOR DELIVERY OF miRNAS AND PROTEIN CODING SEQUENCES |
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| EP2530157B1 (en) * | 2003-07-31 | 2016-09-28 | Regulus Therapeutics Inc. | Oligomeric compounds and compositions for use in modulation of miRNAs |
| WO2010027838A1 (en) * | 2008-08-27 | 2010-03-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Mir 204, mir 211, their anti-mirs, and therapeutic uses of same |
| US20160304865A1 (en) * | 2013-09-26 | 2016-10-20 | Friedrich Miescher Institute For Biomedical Research | Tools and methods using mirna 182, 96 and/or 183 for treating pathologies |
| GB201400598D0 (en) * | 2014-01-14 | 2014-03-05 | Univ Glasgow | Materials and methods for modulation of tendon healing |
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2016
- 2016-03-16 CN CN201680026725.5A patent/CN107532181A/zh active Pending
- 2016-03-16 JP JP2017549044A patent/JP2018509912A/ja active Pending
- 2016-03-16 AU AU2016233311A patent/AU2016233311A1/en not_active Abandoned
- 2016-03-16 US US15/558,505 patent/US20180080023A1/en not_active Abandoned
- 2016-03-16 CA CA2979825A patent/CA2979825A1/en not_active Abandoned
- 2016-03-16 EP EP16765657.8A patent/EP3271464A4/en not_active Withdrawn
- 2016-03-16 WO PCT/US2016/022645 patent/WO2016149370A1/en not_active Ceased
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| CN101842381A (zh) * | 2007-08-27 | 2010-09-22 | 波士顿生物医药公司 | 作为微小rna模拟物或抑制剂的不对称rna双链体的组合物 |
| WO2009137807A2 (en) * | 2008-05-08 | 2009-11-12 | Asuragen, Inc. | Compositions and methods related to mirna modulation of neovascularization or angiogenesis |
| US20130225652A1 (en) * | 2009-08-24 | 2013-08-29 | Guillaume Chorn | Segmented micro rna mimetics |
| WO2014100252A1 (en) * | 2012-12-18 | 2014-06-26 | University Of Washington Through Its Center For Commercialization | Methods and compositions to modulate rna processing |
| US20150051267A1 (en) * | 2013-08-16 | 2015-02-19 | Purdue Research Foundation | BICISTRONIC GENE TRANSFER TOOLS FOR DELIVERY OF miRNAS AND PROTEIN CODING SEQUENCES |
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| SHYAMAL DILHAN WEERARATNE等: "Pleiotropic effects of miR-183~96~182 converge to regulate cell survival, proliferation and migration in medulloblastoma", 《ACTA NEUROPATHOLOGICA》 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110013486A (zh) * | 2019-03-27 | 2019-07-16 | 浙江大学 | mmu-miR-183-5p在制备抑制胚胎着床的药物中的应用 |
| CN110013486B (zh) * | 2019-03-27 | 2021-08-17 | 浙江大学 | mmu-miR-183-5p在制备抑制胚胎着床的药物中的应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016149370A1 (en) | 2016-09-22 |
| CA2979825A1 (en) | 2016-09-22 |
| AU2016233311A1 (en) | 2017-10-05 |
| JP2018509912A (ja) | 2018-04-12 |
| US20180080023A1 (en) | 2018-03-22 |
| EP3271464A4 (en) | 2018-10-31 |
| EP3271464A1 (en) | 2018-01-24 |
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