CN107532119A - 用于微流体装置的培养站 - Google Patents

用于微流体装置的培养站 Download PDF

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Publication number
CN107532119A
CN107532119A CN201680023432.1A CN201680023432A CN107532119A CN 107532119 A CN107532119 A CN 107532119A CN 201680023432 A CN201680023432 A CN 201680023432A CN 107532119 A CN107532119 A CN 107532119A
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China
Prior art keywords
microfluidic device
microfluidic
station
flow
culture
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Pending
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CN201680023432.1A
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English (en)
Chinese (zh)
Inventor
凯斯·J·布林格
罗素·A·纽斯壮
J·坦纳·内维尔
J·M·麦克尤恩
大卫·A·威斯贝克
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Bruker Cellular Analysis Inc
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Berkeley Lights Inc
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Publication of CN107532119A publication Critical patent/CN107532119A/zh
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    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
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    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/08—Flask, bottle or test tube
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    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
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    • C12M23/26—Constructional details, e.g. recesses, hinges flexible
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    • C12M23/34—Internal compartments or partitions
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    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/38—Caps; Covers; Plugs; Pouring means
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    • C12M23/44—Multiple separable units; Modules
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    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/50—Means for positioning or orientating the apparatus
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    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
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    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C—CHEMISTRY; METALLURGY
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    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
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    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/06—Means for regulation, monitoring, measurement or control, e.g. flow regulation of illumination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22—Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • C—CHEMISTRY; METALLURGY
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    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

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  • Immunology (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201680023432.1A 2015-04-22 2016-04-21 用于微流体装置的培养站 Pending CN107532119A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562178960P 2015-04-22 2015-04-22
US62/178,960 2015-04-22
PCT/US2016/028661 WO2016172350A1 (en) 2015-04-22 2016-04-21 Culturing station for microfluidic device

Publications (1)

Publication Number Publication Date
CN107532119A true CN107532119A (zh) 2018-01-02

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Country Status (12)

Country Link
US (1) US20160340632A1 (https=)
EP (1) EP3286298A1 (https=)
JP (3) JP6805166B2 (https=)
KR (2) KR102546378B1 (https=)
CN (1) CN107532119A (https=)
AU (2) AU2016250580B2 (https=)
CA (1) CA2982412C (https=)
HK (1) HK1248750A1 (https=)
IL (2) IL290119B2 (https=)
SG (2) SG10202011358PA (https=)
TW (1) TWI712686B (https=)
WO (1) WO2016172350A1 (https=)

Cited By (4)

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CN109465040A (zh) * 2018-10-16 2019-03-15 佛山翼卿科技有限公司 一种微流控芯片的密封装置
CN110064445A (zh) * 2018-01-24 2019-07-30 伊鲁米那股份有限公司 流体缓冲
CN112041071A (zh) * 2018-05-15 2020-12-04 宝洁公司 微流体料盒和包括该微流体料盒的微流体递送装置
CN114630890A (zh) * 2019-08-13 2022-06-14 弗拉斯沃克斯有限责任公司 用于细胞培养系统的工作周期

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CN110268108B (zh) 2016-12-12 2022-09-06 埃克切拉生物科学公司 用于使用微毛细管阵列进行筛选的方法和系统
EP3562796B1 (en) 2016-12-30 2023-04-19 Xcella Biosciences, Inc. Multi-stage sample recovery system
KR20200026878A (ko) 2017-06-06 2020-03-11 지머젠 인코포레이티드 균류 균주를 개량하기 위한 htp 게놈 공학 플랫폼
US11926814B2 (en) * 2017-08-23 2024-03-12 Northwestern University Multi-chamber fluidic platform
CN111201434A (zh) * 2017-10-16 2020-05-26 瑞泽恩制药公司 用于控制细胞培养物中的过程变量的原位拉曼光谱系统和方法
BR112020024839A2 (pt) 2018-06-06 2021-05-18 Zymergen Inc. manipulação de genes envolvidos em transdução de sinal para controlar a morfologia fúngica durante a fermentação e produção
CN112703059A (zh) * 2018-07-12 2021-04-23 伯克利之光生命科技公司 针对抗病性状筛选植物原生质体
GB201812192D0 (en) 2018-07-26 2018-09-12 Ttp Plc Variable temperature reactor, heater and control circuit for the same
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
BR112021006773A2 (pt) * 2018-10-10 2021-07-13 Stamm Vegh Corporation microbiorreator de fluxo contínuo
ES3039910T3 (en) 2018-12-06 2025-10-27 Xcella Biosciences Inc Lateral loading of microcapillary arrays
WO2020168258A1 (en) 2019-02-15 2020-08-20 Berkeley Lights, Inc. Laser-assisted repositioning of a micro-object and culturing of an attachment-dependent cell in a microfluidic environment
JP7209079B2 (ja) * 2019-03-19 2023-01-19 富士フイルム株式会社 細胞培養システム及び細胞培養方法
WO2020189219A1 (ja) 2019-03-19 2020-09-24 富士フイルム株式会社 情報処理装置、細胞培養システム、情報処理方法、及び情報処理プログラム
WO2020223555A1 (en) 2019-04-30 2020-11-05 Berkeley Lights, Inc. Methods for encapsulating and assaying cells
EP3839037B1 (en) * 2019-12-20 2022-08-17 Astraveus Bioprocessing device
EP4450281A3 (en) 2020-02-03 2025-01-22 Stamm Vegh Corporation Platform, systems, and devices for 3d printing
DE102020107599B3 (de) * 2020-03-19 2021-07-22 Ibidi Gmbh Verfahren zur Kultivierung von Zellen
EP4180510A4 (en) * 2020-07-07 2024-08-21 Shimadzu Corporation CELL CULTURE SYSTEM
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
CN115885031A (zh) * 2020-08-26 2023-03-31 株式会社岛津制作所 细胞培养容器和细胞培养系统
KR102605221B1 (ko) * 2021-07-02 2023-11-24 고려대학교 산학협력단 세포 광자극 장치
US12252678B2 (en) 2021-12-01 2025-03-18 Microfluidx Ltd Systems and methods for bioprocessing
TWI833614B (zh) * 2023-03-23 2024-02-21 揚朋科技股份有限公司 細胞製備系統
TWI903592B (zh) * 2024-06-26 2025-11-01 國立成功大學 組織檢測方法

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