CN107531900A - 聚合物二甲双胍和其作为治疗剂和作为递送载体的用途 - Google Patents

聚合物二甲双胍和其作为治疗剂和作为递送载体的用途 Download PDF

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Publication number
CN107531900A
CN107531900A CN201680026275.XA CN201680026275A CN107531900A CN 107531900 A CN107531900 A CN 107531900A CN 201680026275 A CN201680026275 A CN 201680026275A CN 107531900 A CN107531900 A CN 107531900A
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polymer
metformin
polymet
integer
lph
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Chinese (zh)
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L.黄
Y.赵
S.郭
K.施
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University of North Carolina at Chapel Hill
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University of North Carolina at Chapel Hill
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
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    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
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CN201680026275.XA 2015-03-06 2016-03-04 聚合物二甲双胍和其作为治疗剂和作为递送载体的用途 Pending CN107531900A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562129276P 2015-03-06 2015-03-06
US62/129276 2015-03-06
PCT/US2016/020921 WO2016144766A1 (en) 2015-03-06 2016-03-04 Polymeric metformin and its use as a therapeutic agent and as a delivery vehicle

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US (1) US10426745B2 (enExample)
EP (1) EP3265503A4 (enExample)
JP (1) JP2018513883A (enExample)
CN (1) CN107531900A (enExample)
AU (1) AU2016229152A1 (enExample)
CA (1) CA2978885A1 (enExample)
WO (1) WO2016144766A1 (enExample)

Cited By (1)

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CN113387996A (zh) * 2021-07-15 2021-09-14 郑州大学 一种五环三萜双胍偶联物及其制备方法和应用

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US11202838B2 (en) * 2015-08-14 2021-12-21 Nutech Ventures Substrate delivery of embedded liposomes
US11040055B2 (en) 2016-12-14 2021-06-22 China Medical University Method of treating diabetic retinopathy or wet type adult macular degeneration
CN109620968A (zh) * 2017-10-09 2019-04-16 华东师范大学 一种用于基因治疗或转染的组合物及其制备方法和用途
WO2019135715A1 (en) * 2018-01-05 2019-07-11 Nanyang Technological University Lipid-polymer hybrid nanoparticles
CN110638690B (zh) * 2019-03-01 2021-06-04 上海澄穆生物科技有限公司 一种人工外泌体复合物的制备方法及应用
CN114796491B (zh) * 2022-04-27 2023-01-31 中国药科大学 一种抗体修饰的抗肿瘤靶向递药与联合治疗系统及其制备方法和应用
CN116473077B (zh) * 2023-05-08 2025-04-11 广东方中高新材料有限公司 一种n,n配位的镓配合物抗菌剂的合成和应用

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CN101250263A (zh) * 2007-11-28 2008-08-27 广州科仁机电有限公司 一种多元胺与胍盐预聚物、聚合物及其制备方法和应用
CN102203173A (zh) * 2008-09-19 2011-09-28 3M创新有限公司 配体接枝官能化基材
CN102844662A (zh) * 2010-03-03 2012-12-26 3M创新有限公司 配体胍基官能化聚合物
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113387996A (zh) * 2021-07-15 2021-09-14 郑州大学 一种五环三萜双胍偶联物及其制备方法和应用
CN113387996B (zh) * 2021-07-15 2022-06-07 郑州大学 一种五环三萜双胍偶联物及其制备方法和应用

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CA2978885A1 (en) 2016-09-15
EP3265503A4 (en) 2018-11-14
US10426745B2 (en) 2019-10-01
AU2016229152A1 (en) 2017-10-26
JP2018513883A (ja) 2018-05-31
US20180055792A1 (en) 2018-03-01
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