CN107523626A - 一组用于活动性肺结核无创诊断的外周血基因标记物 - Google Patents
一组用于活动性肺结核无创诊断的外周血基因标记物 Download PDFInfo
- Publication number
- CN107523626A CN107523626A CN201710860947.3A CN201710860947A CN107523626A CN 107523626 A CN107523626 A CN 107523626A CN 201710860947 A CN201710860947 A CN 201710860947A CN 107523626 A CN107523626 A CN 107523626A
- Authority
- CN
- China
- Prior art keywords
- seq
- dna
- artificial
- peripheral blood
- active tuberculosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Description
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710860947.3A CN107523626B (zh) | 2017-09-21 | 2017-09-21 | 一组用于活动性肺结核无创诊断的外周血基因标记物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710860947.3A CN107523626B (zh) | 2017-09-21 | 2017-09-21 | 一组用于活动性肺结核无创诊断的外周血基因标记物 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN107523626A true CN107523626A (zh) | 2017-12-29 |
CN107523626B CN107523626B (zh) | 2021-04-13 |
Family
ID=60736982
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710860947.3A Active CN107523626B (zh) | 2017-09-21 | 2017-09-21 | 一组用于活动性肺结核无创诊断的外周血基因标记物 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN107523626B (zh) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111103426A (zh) * | 2019-12-19 | 2020-05-05 | 广州市妇女儿童医疗中心 | Lap3作为儿童腺病毒肺炎诊断标志物的应用 |
WO2020198990A1 (zh) * | 2019-03-29 | 2020-10-08 | 西南大学 | 结核病标志物在结核病诊断和疗效评估中的应用 |
CN112114146A (zh) * | 2019-06-19 | 2020-12-22 | 中国人民解放军总医院第八医学中心 | 一种用于诊断活动性结核病的试剂盒 |
WO2021052049A1 (zh) * | 2019-09-17 | 2021-03-25 | 浙江大学 | 以ankrd22为靶标在制备胃肠粘膜修复保护剂中的应用 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102150043A (zh) * | 2008-06-25 | 2011-08-10 | 贝勒研究院 | 结核分枝杆菌感染的血液转录标签 |
WO2014019977A1 (en) * | 2012-07-31 | 2014-02-06 | Imperial Innovations Limited | Diagnosis of active tuberculosis by determining the mrna expression levels of marker genes in blood |
WO2014093872A1 (en) * | 2012-12-13 | 2014-06-19 | Baylor Research Institute | Blood transcriptional signatures of active pulmonary tuberculosis and sarcoidosis |
WO2017081618A1 (en) * | 2015-11-11 | 2017-05-18 | University Of Cape Town | Biomarkers for prospective determination of risk for development of active tuberculosis |
CN107058521A (zh) * | 2017-03-17 | 2017-08-18 | 中国科学院北京基因组研究所 | 一种检测人体免疫状态的检测系统 |
-
2017
- 2017-09-21 CN CN201710860947.3A patent/CN107523626B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102150043A (zh) * | 2008-06-25 | 2011-08-10 | 贝勒研究院 | 结核分枝杆菌感染的血液转录标签 |
WO2014019977A1 (en) * | 2012-07-31 | 2014-02-06 | Imperial Innovations Limited | Diagnosis of active tuberculosis by determining the mrna expression levels of marker genes in blood |
WO2014093872A1 (en) * | 2012-12-13 | 2014-06-19 | Baylor Research Institute | Blood transcriptional signatures of active pulmonary tuberculosis and sarcoidosis |
WO2017081618A1 (en) * | 2015-11-11 | 2017-05-18 | University Of Cape Town | Biomarkers for prospective determination of risk for development of active tuberculosis |
CN107058521A (zh) * | 2017-03-17 | 2017-08-18 | 中国科学院北京基因组研究所 | 一种检测人体免疫状态的检测系统 |
Non-Patent Citations (3)
Title |
---|
GEO ACCESSION:GPL570: "[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array", 《NCBI-GEO,HTTPS://WWW.NCBI.NLM.NIH.GOV/GEO/QUERY/ACC.CGI?ACC=GPL570》 * |
MATTHEW P R BERRY ET AL.: "An Interferon-Inducible Neutrophil-Driven Blood Transcriptional Signature in Human Tuberculosis", 《NATURE》 * |
NICHOLAS D WALTER ET AL.: "Blood Transcriptional Biomarkers for Active Tuberculosis Among Patients in the United States: A Case-Control Study With Systematic Cross-Classifier Evaluation", 《J CLIN MICROBIOL》 * |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020198990A1 (zh) * | 2019-03-29 | 2020-10-08 | 西南大学 | 结核病标志物在结核病诊断和疗效评估中的应用 |
CN113631723A (zh) * | 2019-03-29 | 2021-11-09 | 西南大学 | 结核病标志物在结核病诊断和疗效评估中的应用 |
CN113631723B (zh) * | 2019-03-29 | 2023-11-14 | 西南大学 | 结核病标志物在结核病诊断和疗效评估中的应用 |
CN112114146A (zh) * | 2019-06-19 | 2020-12-22 | 中国人民解放军总医院第八医学中心 | 一种用于诊断活动性结核病的试剂盒 |
WO2021052049A1 (zh) * | 2019-09-17 | 2021-03-25 | 浙江大学 | 以ankrd22为靶标在制备胃肠粘膜修复保护剂中的应用 |
CN111103426A (zh) * | 2019-12-19 | 2020-05-05 | 广州市妇女儿童医疗中心 | Lap3作为儿童腺病毒肺炎诊断标志物的应用 |
CN111103426B (zh) * | 2019-12-19 | 2022-10-21 | 广州市妇女儿童医疗中心 | Lap3作为儿童腺病毒肺炎诊断标志物的应用 |
Also Published As
Publication number | Publication date |
---|---|
CN107523626B (zh) | 2021-04-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Hu et al. | Gut microbiota associated with pulmonary tuberculosis and dysbiosis caused by anti-tuberculosis drugs | |
CN107523626A (zh) | 一组用于活动性肺结核无创诊断的外周血基因标记物 | |
KR102330639B1 (ko) | 과민성대장증후군 특이적 미생물 바이오마커와 이를 이용하여 과민성대장증후군의 위험도를 예측하는 방법 | |
WO2016050110A1 (en) | Biomarkers for rheumatoid arthritis and usage thereof | |
CN107058521B (zh) | 一种检测人体免疫状态的检测系统 | |
CN108474037A (zh) | 普氏栖粪杆菌亲缘组i和/或亲缘组ii成员的定量方法及其作为生物标志物的用途 | |
Araos et al. | Microbial disruption indices to detect colonization with multidrug-resistant organisms | |
de La Cochetière et al. | Human intestinal microbiota gene risk factors for antibiotic-associated diarrhea: Perspectives for prevention: Risk factors for antibiotic-associated diarrhea | |
CN106011154B (zh) | 一种致肝脓肿肺炎克雷伯菌分子检测试剂盒及其应用 | |
CN107208149B (zh) | 结直肠癌相关疾病的生物标志物 | |
Sharma et al. | Exploring the Genetic Basis of Tuberculosis Susceptibility in Human Populations | |
WO2022235518A9 (en) | Method for diagnosing active tuberculosis and progression to active tuberculosis | |
CN108064273B (zh) | 结直肠癌相关疾病的生物标志物 | |
KR102101500B1 (ko) | 신장이식 환자의 급성거부반응 진단용 소변 전사체 및 이의 용도 | |
CN112048552B (zh) | 诊断重症肌无力的肠道菌群及其应用 | |
CN107488724A (zh) | 用于活动性肺结核无创诊断的外周血环状rna标记物及应用 | |
CN110527721B (zh) | 一种陈旧性结核病标志物及其应用 | |
Kang et al. | DOP49 Metagenomic Characterisation of The Colonic Mucosa-Associated Microbiota Reveals Novel Microbes and Communities in Health and Crohn’s disease. The ENIGMA study. | |
Montassier et al. | Human intestinal microbiota gene risk factors for antibiotic-associated diarrhea: perspectives for prevention | |
Lieshout et al. | MOLECULAR EPIDEMIOLOGY OF GIARDIA LAMBLIA IN TRAVELLERS. | |
Al–Ameri et al. | Molecular Diagnosis of Yeasts Isolated From Women with Vaginal Candidiasis | |
KR20230161899A (ko) | 항류마티스제의 치료반응을 예측할 수 있는 장내세균 | |
Wood et al. | 6: T cell activation in south african HIV-exposed infants linked to ochratoxin exposure | |
EP4320262A1 (en) | Methods of diagnosis of respiratory viral infections | |
WO2024054572A1 (en) | Methods of detecting sjögren's syndrome using salivary exosomes |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20180514 Address after: 210000 403, room 8, Hua Gui Yuan, 69-1 Beijing West Road, Gulou District, Nanjing, Jiangsu. Applicant after: Gu Wanjun Applicant after: Qian Zhongqing Applicant after: Zhou Tong Address before: 210000 403, room 8, Hua Gui Yuan, 69-1 Beijing West Road, Gulou District, Nanjing, Jiangsu. Applicant before: Gu Wanjun |
|
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20200721 Address after: Gulou District of Nanjing City, Jiangsu province 210000 Beijing Road No. 69-1 China rose garden building 403 room 8 Applicant after: Gu Wanjun Applicant after: Qian Zhongqing Address before: Gulou District of Nanjing City, Jiangsu province 210000 Beijing Road No. 69-1 China rose garden building 403 room 8 Applicant before: Gu Wanjun Applicant before: Qian Zhongqing Applicant before: Zhou Tong |
|
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Gu Wanjun Inventor after: Yin Xiaofeng Inventor after: Qian Zhongqing Inventor before: Gu Wanjun Inventor before: Zhou Tong Inventor before: Yin Xiaofeng Inventor before: Qian Zhongqing |
|
GR01 | Patent grant | ||
GR01 | Patent grant |