CN107519302A - A kind of external Chinese medicinal liquid for treating gynecological disease - Google Patents
A kind of external Chinese medicinal liquid for treating gynecological disease Download PDFInfo
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- CN107519302A CN107519302A CN201610449310.0A CN201610449310A CN107519302A CN 107519302 A CN107519302 A CN 107519302A CN 201610449310 A CN201610449310 A CN 201610449310A CN 107519302 A CN107519302 A CN 107519302A
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/808—Scrophularia (figwort)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Chemical & Material Sciences (AREA)
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- Public Health (AREA)
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- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
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- Alternative & Traditional Medicine (AREA)
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- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
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- Gynecology & Obstetrics (AREA)
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- Urology & Nephrology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to field of Chinese herbal, and in particular to a kind of external Chinese medicinal liquid for treating gynecological disease, it is characterised in that it is mainly made up by weight ratio of following raw materials according component：20 ~ 30 parts of hairyvein agrimony, 20 ~ 30 parts of cockscomb, 20 ~ 30 parts of kuh-seng, 20 ~ 25 parts of rhizoma atractylodis, 20 ~ 25 parts of diaphragma juglandis, 15 ~ 25 parts of the Japanese ardisia, 15 ~ 30 parts of dandelion, 10 ~ 30 parts of the fruit of summer cypress, 10 ~ 20 parts of radix scrophulariae, 5 ~ 10 parts of borneol, acetic acid chlorhexidine is by the 0.5 ‰ of gone out amount of liquid medicine.Compared with prior art, it is an advantage of the invention that：1）Formulation is aqua, and pH value is consistent with the pH value of human vagina, can improve and safeguard the balance of intravaginal flora, gentle non-stimulated.2）Pure Chinese medicine non-antibiotic, grown by suppressing harmful levels of pathogens, adjust the colony balance and acid-base balance of intravaginal, for the purpose of the vagina and cervical mucosal of repairing breakage, vagina self-protection system is gradually restored balance.
Description
Technical field
The invention belongs to field of Chinese herbal, and in particular to a kind of external Chinese medicinal liquid for treating gynecological disease.
Background technology
Gynecological disease is women common disease, frequently-occurring disease, such as pruritus vulvue, all kinds vaginitis（Mould, trichomonad, bacterium are senile）, vaginal relaxation, cervicitis, cervical erosion etc., health is not only influenceed, also life and work is impacted.Modern medicine study thinks that " vaginitis " is the inflammation of connective tissue under vagina mucosa and mucous membrane.Common vaginitis has bacterial vaginitis, trichomonas vaginitis, colpomycosis, senile vahinitis, relevant medical tissue was once studied 1181 vaginitis, it was found that 41% is bacillary, 27% is fungoid, 24% is trichomonas, senile vahinitis betide menopause after, after ovary excision person or pelvic cavity radiation therapy, its incidence of disease is it is reported that up to 98.5%.
The product for the treatment of gynaecological disease now, is western medicine antibiotics composition mostly, kills harmful bacteria during treatment and also kills beneficial bacterium simultaneously, destroys intravaginal colony balance, acid-base balance, harmful levels of pathogens is availed oneself of the opportunity to get in, cause the state of an illness again and again.And mostly in formulation is effervescent tablet, ointment and gel etc..Effervescent tablet contains gas-producing disintegrant（Main component is the mixture of organic acid, sodium carbonate and sodium acid carbonate）, advantage can help medicine preferably to disperse, but with gynaecology's product, gas-producing disintegrant meets water and produces disintegration reflection, it is easy to tender vagina of burning, and it is scattered after medicine can not fully absorb.Also ointment and gel, the composition of ointment is aqueous phase, oil phase and emulsifying agent, and gel is usually to add the allotments such as gel former, ice crystal forming agent to form.Seem easy to use, but emulsifying agent therein, forming agent etc. are unhelpful to body, aggravate body burden on the contrary.Based on above reason, this herb liquid of independent research, solves problem above in person.
The content of the invention
It is an object of the invention to provide a kind of external Chinese medicinal liquid for treating gynecological disease; any antibiotic composition is not contained; first pass through the colony balance and acid-base balance of regulation intravaginal; suppress harmful levels of pathogens growth; repair damaged vagina and cervical mucosal; then progressively cleaning is attached to toxin and harmful bacteria inside vagina, vagina self-protection system is gradually restored balance.
To achieve the above object, the present invention is achieved through the following technical solutions：
A kind of external Chinese medicinal liquid for treating gynecological disease, its Chinese medicinal effective-part composition are mainly made up by weight ratio of following raw materials according component：20 ~ 30 parts of hairyvein agrimony, 20 ~ 30 parts of cockscomb, 20 ~ 30 parts of kuh-seng, 20 ~ 25 parts of rhizoma atractylodis, 20 ~ 25 parts of diaphragma juglandis, 15 ~ 25 parts of the Japanese ardisia, 15 ~ 30 parts of dandelion, 10 ~ 30 parts of the fruit of summer cypress, 10 ~ 20 parts of radix scrophulariae, 5 ~ 10 parts of borneol, acetic acid chlorhexidine is by the 0.5 ‰ of gone out amount of liquid medicine；The preparation method of the herb liquid is：Above-mentioned drying traditional Chinese medicinal materials, add in the water of 17 ~ 18 times of amounts and soak 30 ~ 40 minutes, infusion 20-25 minutes, filter out soup, waste, be cooled to room temperature, add acetic acid chlorhexidine in proportion, stir and produce.
Wherein Chinese medicinal effective-part composition preferred weight part ratio is：30 parts of hairyvein agrimony, 30 parts of cockscomb, 20 parts of kuh-seng, 20 parts of rhizoma atractylodis, 20 parts of diaphragma juglandis, 15 parts of the Japanese ardisia, 15 parts of dandelion, 10 parts of the fruit of summer cypress, 10 parts of radix scrophulariae, 5 parts of borneol, acetic acid chlorhexidine is by the 0.5 ‰ of gone out amount of liquid medicine.
The external Chinese medicinal liquid of another kind treatment gynecological disease, its Chinese medicinal effective-part composition are mainly made up by weight ratio of following raw materials according component：20 ~ 30 parts of hairyvein agrimony, 20 ~ 30 parts of cockscomb, 20 ~ 30 parts of kuh-seng, 20 ~ 25 parts of rhizoma atractylodis, 20 ~ 25 parts of diaphragma juglandis, 15 ~ 25 parts of the Japanese ardisia, 15 ~ 30 parts of dandelion, 10 ~ 30 parts of the fruit of summer cypress, 10 ~ 20 parts of radix scrophulariae, 20 ~ 30 parts of golden cypress, 5 ~ 10 parts of borneol, acetic acid chlorhexidine is by the 0.5 ‰ of gone out amount of liquid medicine；The preparation method of the herb liquid is：Above-mentioned drying traditional Chinese medicinal materials, add in the water of 17 ~ 18 times of amounts and soak 30 ~ 40 minutes, infusion 20-25 minutes, filter out soup, waste, be cooled to room temperature, add acetic acid chlorhexidine in proportion, stir and produce.
Wherein Chinese medicinal effective-part composition preferred weight part ratio is：30 parts of hairyvein agrimony, 30 parts of cockscomb, 20 parts of kuh-seng, 20 parts of rhizoma atractylodis, 20 parts of diaphragma juglandis, 15 parts of the Japanese ardisia, 15 parts of dandelion, 10 parts of the fruit of summer cypress, 10 parts of radix scrophulariae, 20 parts of golden cypress, 5 parts of borneol, acetic acid chlorhexidine is by the 0.5 ‰ of gone out amount of liquid medicine.
The application method of the herb liquid is：Such as pruritus vulvue, rinsed using hip bath, once a day, hip bath 15-20 minutes；Vaginitis, cervicitis, cervical erosion etc. in this way, after hip bath is rinsed, then with Vaginal lavages medicine applying instrument, decoction is injected vagina depths, daily 1-2 times, 3 ~ 5ml, lies in bed 3 ~ 5 minutes after medication every time.
Fang Zhong, hairyvein agrimony is warm-natured, and acrid flavour is puckery, nontoxic；Function：Astringing to arrest bleeding, stop dysentery, desinsection, for treating boil carbuncle swells, the inferior disease of pruritus vulvae band.Cockscomb, cool in nature, sweet-puckery flavor, function：Controlling of bleeding with astringents, stop-band, stop dysentery, it is more than for uterine bleeding, hemorrhoid blood, leukorrhea with reddish discharge, protracted dysentery.Rhizoma atractylodis, acrid flavour is bitter, warm-natured；Drying damp and strengthening spleen, the expelling wind and clearing away cold of energy, for abdominal fullness and distention, diarrhea oedema.Diaphragma juglandis, bitter and puckery flavor is mild-natured, nontoxic；Effect relieving leukorrhea by astringents, suitable for leukorrhea, hematuria, uterine bleeding.The Japanese ardisia, gas is pungent, and taste is put down, nontoxic；Disease diaphragm gas when curing mainly, go wind phlegm, removing toxic substances blood-breaking.Dandelion, flat property and sweet taste slight bitter；There is clearing heat and detoxicating, dispersing swelling and dissipating binds effect.The fruit of summer cypress, cold in nature, acrid flavour is bitter；With clearing heat and promoting diuresis, the effect of dispelling wind and arresting itching, under difficulty and pain in micturition, pruritus vulvae band, rubella, eczema, pruitus etc..Radix scrophulariae, sweet-bitter flavor is salty, cold nature；Effect clearing heat and cooling blood, purging intense heat and detonicating, enriching yin.It is golden cypress bitter, cold in nature；It is heat-clearing and detoxifying drug, heat-clearing and damp-drying drug, cures mainly under stranguria with turbid discharge, band, skin sore, skin eczema.Matrine is from a kind of alkaloid of cassia leguminous plant kuh-seng root extraction, has antibacterial and anti-inflammation functions.Borneol also known as natural d-borneol, Borneolum, have and lead to all keys, dissipate stagnated fire, remove the medicinal functions such as screen improving eyesight, swelling and pain relieving, heat reliving and toxin-eliminating, anti-inflammatory analgetic, removing necrosis, promoting granulation.Chlorhexidine acetate is Cidex-7, has great broad-spectrum antibacterial, bactericidal action, effective to gram positive bacteria and gram-negative bacteria, the outer sterilization for hand and skin extensively, rinses wound.
After these drug regimens so that each efficacy of drugs produces synergy, and gynecological disease is treated so as to fundamentally conditioning engine body qi blood balance.These medicines are treated from clearing heat and detoxicating, hemostasia and promoting granulation angle, so as to realize the purpose treated both principal and secondary aspect of disease.
Compared with prior art, the beneficial effects of the invention are as follows：1）Formulation is aqua, does not add any matrix, and into after vagina, can go directly uterine neck depths, is absorbed rapidly, and the pH value of this product is consistent with the pH value of human vagina, can improve and safeguard the balance of intravaginal flora, gentle non-stimulated.2）Pure Chinese medicine non-antibiotic; it is not simple sterilization sterilising prods; but grown by suppressing harmful levels of pathogens; adjust the colony balance and acid-base balance of intravaginal; for the purpose of the vagina and cervical mucosal of repairing breakage; then progressively cleaning is attached to toxin and harmful bacteria inside vagina, vagina self-protection system is gradually restored balance.
Embodiment
The preparation method of the present invention is described further with reference to embodiment：
Embodiment 1
A kind of external Chinese medicinal liquid for treating gynecological disease, its Chinese medicinal effective-part composition are mainly made up of following raw materials according component proportion：30 grams of hairyvein agrimony, 30 grams of cockscomb, 20 grams of kuh-seng, 20 grams of rhizoma atractylodis, 20 grams of diaphragma juglandis, 15 grams of the Japanese ardisia, 15 grams of dandelion, 10 grams of the fruit of summer cypress, 10 grams of radix scrophulariae, 5 grams of borneol, 0.5 gram of acetic acid chlorhexidine.The preparation method of the herb liquid is：Above-mentioned drying traditional Chinese medicinal materials, add in 3000ml water and soak 30 ~ 40 minutes, infusion 20-25 minutes, filter out 1000ml soups, waste, be cooled to room temperature, add 0.5 gram of acetic acid chlorhexidine, stir and produce.
The application method of the herb liquid is：Such as pruritus vulvue, rinsed using hip bath, once a day, hip bath 15-20 minutes；Vaginitis, cervicitis, cervical erosion etc. in this way, after hip bath is rinsed, then with Vaginal lavages medicine applying instrument, decoction is injected vagina depths, daily 1-2 times, 3 ~ 5ml, lies in bed 3 ~ 5 minutes after medication, be used in conjunction 15 days every time.
Embodiment 2
A kind of external Chinese medicinal liquid for treating gynecological disease, its Chinese medicinal effective-part composition are mainly made up of following raw materials according component proportion：25 grams of hairyvein agrimony, 20 grams of cockscomb, 25 grams of kuh-seng, 25 grams of rhizoma atractylodis, 20 grams of diaphragma juglandis, 15 grams of the Japanese ardisia, 20 grams of dandelion, 10 grams of the fruit of summer cypress, 10 grams of radix scrophulariae, 5 grams of borneol, 0.5 gram of acetic acid chlorhexidine.The preparation method of the herb liquid is：Above-mentioned drying traditional Chinese medicinal materials, add in 3000ml water and soak 30 ~ 40 minutes, infusion 20-25 minutes, filter out 1000ml soups, waste, be cooled to room temperature, add 0.5 gram of acetic acid chlorhexidine, stir and produce.The application method of the herb liquid is the same as embodiment 1.
Embodiment 3
A kind of external Chinese medicinal liquid for treating gynecological disease, its Chinese medicinal effective-part composition are mainly made up of following raw materials according component proportion：30 grams of hairyvein agrimony, 30 grams of cockscomb, 20 grams of kuh-seng, 20 grams of rhizoma atractylodis, 20 grams of diaphragma juglandis, 15 grams of the Japanese ardisia, 15 grams of dandelion, 10 grams of the fruit of summer cypress, 10 grams of radix scrophulariae, 20 grams of golden cypress, 5 grams of borneol, 0.6 gram of acetic acid chlorhexidine.The preparation method of the herb liquid is：Above-mentioned drying traditional Chinese medicinal materials, add in 3500ml water and soak 30 ~ 40 minutes, infusion 20-25 minutes, filter out 1200ml soups, waste, be cooled to room temperature, add 0.6 gram of acetic acid chlorhexidine, stir and produce.The application method of the herb liquid is the same as embodiment 1.
1 is see the table below using embodiment 1 to patient census's result of the gained herb liquid of embodiment 3.It is effective including healing and effective in table 1, wherein, healing refers to clinical symptom disappearance, and leukorrhea, pruritus vulvue and relevant sign return to normal, and checks that the recovery of leukorrhea result is normal；Effectively refer to that clinical symptoms disappear substantially, leukorrhea, pruritus vulvue and relevant sign substantially mitigate, and check the inspection of leukorrhea result close to normally.It is invalid to refer to that clinical symptoms and sign without improvement, check leukorrhea result without change.
Table 1
| Embodiment | Number of cases | It is effective | It is invalid | Obvious effective rate（%） |
| Embodiment 1 | 52 | 51 | 1 | 98 |
| Embodiment 2 | 68 | 66 | 2 | 97 |
| Embodiment 3 | 82 | 80 | 2 | 97.6 |
Shown by a large amount of clinical datas, after patient uses herb liquid of the present invention, for pruritus vulvue, all kinds vaginitis（Mould, trichomonad, bacterium are senile）, cervicitis, the gynecological disease patient such as cervical erosion, can once it take effect, and the therapeutic effect of highly significant was obtained in 15 days, while also have improvement result, and persistent to vaginal relaxation, it is free from side effects, it is deep by patient's favorable comment.
Claims (4)
1. a kind of external Chinese medicinal liquid for treating gynecological disease, it is characterised in that its Chinese medicinal effective-part composition is mainly made up by weight ratio of following raw materials according component：20 ~ 30 parts of hairyvein agrimony, 20 ~ 30 parts of cockscomb, 20 ~ 30 parts of kuh-seng, 20 ~ 25 parts of rhizoma atractylodis, 20 ~ 25 parts of diaphragma juglandis, 15 ~ 25 parts of the Japanese ardisia, 15 ~ 30 parts of dandelion, 10 ~ 30 parts of the fruit of summer cypress, 10 ~ 20 parts of radix scrophulariae, 5 ~ 10 parts of borneol, acetic acid chlorhexidine is by the 0.5 ‰ of gone out amount of liquid medicine；The preparation method of the herb liquid is：Above-mentioned drying traditional Chinese medicinal materials, add in the water of 17 ~ 18 times of amounts and soak 30 ~ 40 minutes, infusion 20-25 minutes, filter out soup, waste, be cooled to room temperature, add acetic acid chlorhexidine in proportion, stir and produce.
2. a kind of external Chinese medicinal liquid for treating gynecological disease according to claim 1, it is characterised in that wherein Chinese medicinal effective-part composition preferred weight part ratio is：30 parts of hairyvein agrimony, 30 parts of cockscomb, 20 parts of kuh-seng, 20 parts of rhizoma atractylodis, 20 parts of diaphragma juglandis, 15 parts of the Japanese ardisia, 15 parts of dandelion, 10 parts of the fruit of summer cypress, 10 parts of radix scrophulariae, 5 parts of borneol, acetic acid chlorhexidine is by the 0.5 ‰ of gone out amount of liquid medicine.
3. a kind of external Chinese medicinal liquid for treating gynecological disease, it is characterised in that its Chinese medicinal effective-part composition is mainly made up by weight ratio of following raw materials according component：20 ~ 30 parts of hairyvein agrimony, 20 ~ 30 parts of cockscomb, 20 ~ 30 parts of kuh-seng, 20 ~ 25 parts of rhizoma atractylodis, 20 ~ 25 parts of diaphragma juglandis, 15 ~ 25 parts of the Japanese ardisia, 15 ~ 30 parts of dandelion, 10 ~ 30 parts of the fruit of summer cypress, 10 ~ 20 parts of radix scrophulariae, 20 ~ 30 parts of golden cypress, 5 ~ 10 parts of borneol, acetic acid chlorhexidine is by the 0.5 ‰ of gone out amount of liquid medicine；The preparation method of the herb liquid is：Above-mentioned drying traditional Chinese medicinal materials, add in the water of 17 ~ 18 times of amounts and soak 30 ~ 40 minutes, infusion 20-25 minutes, filter out soup, waste, be cooled to room temperature, add acetic acid chlorhexidine in proportion, stir and produce.
4. a kind of external Chinese medicinal liquid for treating gynecological disease according to claim 3, it is characterised in that wherein Chinese medicinal effective-part composition preferred weight part ratio is：30 parts of hairyvein agrimony, 30 parts of cockscomb, 20 parts of kuh-seng, 20 parts of rhizoma atractylodis, 20 parts of diaphragma juglandis, 15 parts of the Japanese ardisia, 15 parts of dandelion, 10 parts of the fruit of summer cypress, 10 parts of radix scrophulariae, 20 parts of golden cypress, 5 parts of borneol, acetic acid chlorhexidine is by the 0.5 ‰ of gone out amount of liquid medicine.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101623368A (en) * | 2008-07-11 | 2010-01-13 | 王捷 | Drug for treating gynecological diseases and preparation technology thereof |
| CN102205078A (en) * | 2011-05-10 | 2011-10-05 | 安徽宝芝堂药业有限公司 | High-efficiency compound lightyellow sophora root lotion and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101623368A (en) * | 2008-07-11 | 2010-01-13 | 王捷 | Drug for treating gynecological diseases and preparation technology thereof |
| CN102205078A (en) * | 2011-05-10 | 2011-10-05 | 安徽宝芝堂药业有限公司 | High-efficiency compound lightyellow sophora root lotion and preparation method thereof |
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| 魏永华等: "中西医结合治疗念珠菌性阴道炎88例疗效观察", 《现代中西医结合杂志》 * |
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