CN107519030A - 一种美白化妆品 - Google Patents

一种美白化妆品 Download PDF

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Publication number
CN107519030A
CN107519030A CN201710760355.4A CN201710760355A CN107519030A CN 107519030 A CN107519030 A CN 107519030A CN 201710760355 A CN201710760355 A CN 201710760355A CN 107519030 A CN107519030 A CN 107519030A
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Prior art keywords
skin
lightening cosmetic
whitening
effect
present
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张宏宇
顾志明
钱伟
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Suzhou Pavilion Medical Technology Development Co Ltd
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Suzhou Pavilion Medical Technology Development Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

本发明揭示了一种美白化妆品,按照各组分按照重量比例为,其包括8‑12%的甘油,8%‑15的PVA,3‑6%的熊果苷,1‑3%的维生素E,0.6‑1.1%透明质酸钠,0.1‑0.2%三梨酸钾,0.4‑0.6%月桂氮酮,0.2‑0.3%肉桂酸,0.5‑0.8%山奈酚,0.4‑0.6%3‑亚甲基‑6‑异丙基环忆烯,其余为水。与现有技术相比,本发明美白化妆品有益效果在于:化妆品更能达到美白的效果,对美白的效果持续时间更长。

Description

一种美白化妆品
【技术领域】
本发明属于化妆品领域,特别是涉及一种美白化妆品。
【背景技术】
1998年11月18日,美国专利申请了US09/195577号专利,提出了一种含有熊果提取物和还原剂的皮肤增白组合物。该组合物可局部施用于人的皮肤,并且可含有一种或多种增白剂与熊果提取物和还原剂一起提高增白效果。一种增白人的皮肤的方法,包括将一种含有熊果提取物和还原剂的组合物按足以明显地增白皮肤的量和时间局部施用于皮肤。该方法包括将熊果提取物和还原剂掺入已知增白剂并按照足以明显地增白皮肤的量和时间施用于皮肤。
2010年09月01日,中国专利申请号第CN201010125871.8号专利公开了一种美白化妆品及其制备方法和应用。该化妆品由如下按质量百分数计的组分组成:重组人血管生成素0.00001~0.001%,金属硫蛋白0.00001~0.001%,人表皮生长因子0.00001~0.001%,IL-1RA 0.00001~0.001%,超氧化歧化酶0.1~0.5%,低分子肝素钠0.1~0.5%,熊果苷1~5%,稳定剂5~25%,透明质酸0.02~0.3%,甲基丙二醇0.5~5%,乳酸杆菌/绿豆发酵液0.5~3.5%,溶解蛋白酶0.5~5%,维生素C磷酸酯钠0.5~8%,1,2己二醇或1,2辛二醇0.3~0.7%,燕麦β葡聚糖1~5%,大豆异黄酮1~5%,余量为水。美白化妆品可以长期保存,对皮肤无副作用,适合长期使用。
在过去近20年间,人们对以熊果苷作为化妆品的基本物料,进行了不断的改进来提高化妆品的质量和化妆效果,取得了不少的效果。但随着时代的进步,人们对美白化妆品的追求越来越高,因此,企业在不断的提高美白化妆品的性能。
因此,有必要提供一种美白化妆品来提高美白效果。
【发明内容】
本发明的主要目的在于提供一种提高美白化妆品。
本发明通过如下技术方案实现上述目的:一种美白化妆品,按照各组分按照重量比例为,其包括8-12%的甘油,8%-15的PVA,3-6%的熊果苷,1-3%的维生素E,0.6-1.1%透明质酸钠,0.1-0.2%三梨酸钾,0.4-0.6%月桂氮酮,0.2-0.3%肉桂酸,0.5-0.8%山奈酚,0.4-0.6%3-亚甲基-6-异丙基环忆烯,其余为水。
与现有技术相比,本发明美白化妆品有益效果在于:化妆品更能达到美白的效果,对美白的效果持续时间更长。
【具体实施方式】
本发明为一种美白化妆品,按照各组分按照重量比例为,其包括8-12%的甘油,8%-15的PVA(聚乙烯醇),3-6%的熊果苷,1-3%的维生素E,0.6-1.1%透明质酸钠,0.1-0.2%三梨酸钾,0.4-0.6%月桂氮酮,0.2-0.3%肉桂酸,0.5-0.8%山奈酚,0.4-0.6%3-亚甲基-6-异丙基环忆烯,其余为水。
以下通过如下实施例解释本发明。
按照各组分按照重量比例为:
通过上述的配方合成8种美白化妆品,进行对酪氨酸酶活性抑制的差异性进行实验对比,
试验1-8:分别提供1.5ml PBS,2.0ml酪氨酸溶液,30μL酪氨酸酶及分别取各配方美白化妆品0.5ml,
试验9-13:分别提供1.5ml PBS,2.0ml酪氨酸溶液,30μL酪氨酸酶及分别取市面传统的化妆品0.5ml。
经过摇匀,30分钟与1小时孵育过程后的观察,确认对酪氨酸酶活性抑制率分别如下:
通过实验对比,确认本发明中各实施例的美白化妆品对酪氨酸酶活性抑制作用效果是明显的,可以确认,本发明的化妆品更能达到美白的效果,对美白的效果持续时间更长。
以上所述的仅是本发明的一些实施方式。对于本领域的普通技术人员来说,在不脱离本发明创造构思的前提下,还可以做出若干变形和改进,这些都属于本发明的保护范围。

Claims (1)

1.一种美白化妆品,其特征在于:按照各组分按照重量比例为,其包括8-12%的甘油,8%-15的PVA,3-6%的熊果苷,1-3%的维生素E,0.6-1.1%透明质酸钠,0.1-0.2%三梨酸钾,0.4-0.6%月桂氮酮,0.2-0.3%肉桂酸,0.5-0.8%山奈酚,0.4-0.6%3-亚甲基-6-异丙基环忆烯,其余为水。
CN201710760355.4A 2017-08-29 2017-08-29 一种美白化妆品 Pending CN107519030A (zh)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101111244A (zh) * 2004-12-31 2008-01-23 株式会社太平洋 含有山奈酚和槲皮素的透明质酸生成促进用组合物
CN104473178A (zh) * 2005-09-20 2015-04-01 雀巢技术公司 水可分散组合物及其制备方法
CN106420368A (zh) * 2016-11-01 2017-02-22 东华大学 一种敷贴式水凝胶基底面膜的制备方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101111244A (zh) * 2004-12-31 2008-01-23 株式会社太平洋 含有山奈酚和槲皮素的透明质酸生成促进用组合物
CN104473178A (zh) * 2005-09-20 2015-04-01 雀巢技术公司 水可分散组合物及其制备方法
CN106420368A (zh) * 2016-11-01 2017-02-22 东华大学 一种敷贴式水凝胶基底面膜的制备方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
陈东红主编: "《有机化学实验》", 28 February 2009, 华东理工大学出版社 *

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Application publication date: 20171229