CN107518413A - A kind of oligomeric peptide combinations of the albumen of strengthen immunity and preparation method thereof - Google Patents
A kind of oligomeric peptide combinations of the albumen of strengthen immunity and preparation method thereof Download PDFInfo
- Publication number
- CN107518413A CN107518413A CN201710695204.5A CN201710695204A CN107518413A CN 107518413 A CN107518413 A CN 107518413A CN 201710695204 A CN201710695204 A CN 201710695204A CN 107518413 A CN107518413 A CN 107518413A
- Authority
- CN
- China
- Prior art keywords
- albumen
- mineral element
- strengthen immunity
- peptide combinations
- oligomeric peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000036039 immunity Effects 0.000 title claims abstract description 45
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 108010038807 Oligopeptides Proteins 0.000 claims abstract description 41
- 102000015636 Oligopeptides Human genes 0.000 claims abstract description 41
- 239000002366 mineral element Substances 0.000 claims abstract description 41
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 32
- 239000011669 selenium Substances 0.000 claims abstract description 32
- 229910052711 selenium Inorganic materials 0.000 claims abstract description 29
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims abstract description 27
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000011701 zinc Substances 0.000 claims abstract description 24
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 24
- 239000002994 raw material Substances 0.000 claims abstract description 19
- 239000000463 material Substances 0.000 claims abstract description 17
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 16
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 16
- 239000011718 vitamin C Substances 0.000 claims abstract description 16
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 16
- 235000020710 ginseng extract Nutrition 0.000 claims abstract description 14
- 239000000203 mixture Substances 0.000 claims abstract description 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 4
- 235000013361 beverage Nutrition 0.000 claims description 24
- 239000007787 solid Substances 0.000 claims description 24
- 108010073771 Soybean Proteins Proteins 0.000 claims description 9
- 235000003599 food sweetener Nutrition 0.000 claims description 9
- 239000003765 sweetening agent Substances 0.000 claims description 9
- 239000002245 particle Substances 0.000 claims description 5
- 235000019710 soybean protein Nutrition 0.000 claims description 5
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 4
- CANRESZKMUPMAE-UHFFFAOYSA-L Zinc lactate Chemical compound [Zn+2].CC(O)C([O-])=O.CC(O)C([O-])=O CANRESZKMUPMAE-UHFFFAOYSA-L 0.000 claims description 4
- 229940001941 soy protein Drugs 0.000 claims description 4
- WGIWBXUNRXCYRA-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WGIWBXUNRXCYRA-UHFFFAOYSA-H 0.000 claims description 4
- 239000011746 zinc citrate Substances 0.000 claims description 4
- 235000006076 zinc citrate Nutrition 0.000 claims description 4
- 229940068475 zinc citrate Drugs 0.000 claims description 4
- 229940050168 zinc lactate Drugs 0.000 claims description 4
- 239000011576 zinc lactate Substances 0.000 claims description 4
- 235000000193 zinc lactate Nutrition 0.000 claims description 4
- 229920001202 Inulin Polymers 0.000 claims description 3
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 claims description 3
- 229940029339 inulin Drugs 0.000 claims description 3
- 239000004384 Neotame Substances 0.000 claims description 2
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 2
- 239000004376 Sucralose Substances 0.000 claims description 2
- BNBRHCPFVGXQRQ-UHFFFAOYSA-N [Se].O[Se](O)=O Chemical group [Se].O[Se](O)=O BNBRHCPFVGXQRQ-UHFFFAOYSA-N 0.000 claims description 2
- HLIAVLHNDJUHFG-HOTGVXAUSA-N neotame Chemical compound CC(C)(C)CCN[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 HLIAVLHNDJUHFG-HOTGVXAUSA-N 0.000 claims description 2
- 235000019412 neotame Nutrition 0.000 claims description 2
- 108010070257 neotame Proteins 0.000 claims description 2
- 229940013618 stevioside Drugs 0.000 claims description 2
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 2
- 235000019202 steviosides Nutrition 0.000 claims description 2
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims description 2
- 235000019408 sucralose Nutrition 0.000 claims description 2
- 230000036541 health Effects 0.000 abstract description 4
- 150000001413 amino acids Chemical class 0.000 abstract description 3
- 230000002195 synergetic effect Effects 0.000 abstract description 3
- 238000010521 absorption reaction Methods 0.000 abstract description 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 13
- 230000000694 effects Effects 0.000 description 8
- 235000019789 appetite Nutrition 0.000 description 7
- 230000036528 appetite Effects 0.000 description 7
- 230000036737 immune function Effects 0.000 description 5
- 230000006872 improvement Effects 0.000 description 5
- 239000000686 essence Substances 0.000 description 4
- 206010016256 fatigue Diseases 0.000 description 4
- 229930182494 ginsenoside Natural products 0.000 description 4
- 208000033065 inborn errors of immunity Diseases 0.000 description 4
- 208000028529 primary immunodeficiency disease Diseases 0.000 description 4
- 230000003860 sleep quality Effects 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 229940089161 ginsenoside Drugs 0.000 description 3
- 235000013402 health food Nutrition 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 230000002335 preservative effect Effects 0.000 description 3
- 230000007958 sleep Effects 0.000 description 3
- 102000006395 Globulins Human genes 0.000 description 2
- 108010044091 Globulins Proteins 0.000 description 2
- 240000004371 Panax ginseng Species 0.000 description 2
- 206010041349 Somnolence Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 235000008434 ginseng Nutrition 0.000 description 2
- 210000000987 immune system Anatomy 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 230000009545 invasion Effects 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 235000010755 mineral Nutrition 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000012795 verification Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 241000606161 Chlamydia Species 0.000 description 1
- 244000086443 Craterellus fallax Species 0.000 description 1
- 235000007926 Craterellus fallax Nutrition 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 241000204031 Mycoplasma Species 0.000 description 1
- 235000002789 Panax ginseng Nutrition 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 210000001744 T-lymphocyte Anatomy 0.000 description 1
- 101710120037 Toxin CcdB Proteins 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010048259 Zinc deficiency Diseases 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 230000009831 antigen interaction Effects 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 210000003719 b-lymphocyte Anatomy 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000007969 cellular immunity Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000035605 chemotaxis Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000005059 dormancy Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000003563 lymphoid tissue Anatomy 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 210000004493 neutrocyte Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 208000019116 sleep disease Diseases 0.000 description 1
- 208000020685 sleep-wake disease Diseases 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 235000015096 spirit Nutrition 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The present invention relates to health product technology field, and in particular to a kind of oligomeric peptide combinations of the albumen of strengthen immunity and preparation method thereof.Said composition is mainly prepared from the following materials：Albumen oligopeptide 78~85%, ginseng extract 2~5%, vitamin C 0.3~0.6%, mineral element zinc 0.1~0.3%, mineral element selenium 0.01~0.03%.The oligomeric peptide molecular weight of albumen is small, amino acid composition is complete, it is a kind of mixture of the small-molecular peptides based on 7~8 amino acid chains, it can quickly, completely be absorbed by organisms utilization, body is while quickly albumen oligopeptide is absorbed, albumen oligopeptide carries ginseng extract, vitamin C, mineral element zinc and mineral element selenium and is absorbed by organisms, act on cell, lift absorption rate of the body to other raw materials, each raw material is in the amount ranges of restriction simultaneously, produce synergistic function, health-care efficacy of the lifting product to immunity of organisms.
Description
Technical field
The present invention relates to health product technology field, and in particular to a kind of oligomeric peptide combinations of the albumen of strengthen immunity and its
Preparation method.
Background technology
Immunity refers to that body resists external invasion and attack, safeguards the ability of homoiostasis, is the defence of human body itself
Mechanism.Air, which collects, is filled with various microorganisms：Bacterium, virus, mycoplasma, Chlamydia, fungi etc., chemicotherapy are suffered from
The people of the hypoimmunities such as person, the elderly can not resist the invasion of these pathogenic microorganisms at all, clinically most directly performance
It is exactly liable to illness, and because of the frequent sick consumption for having aggravated body, typically have a delicate constitution, be malnutritive, be One's spirits are drooping,
Fatigue and weak, appetite reduction, sleep-disorder etc. show, sick, having an injection to take medicine becomes for homely food, if things go on like this cause body
Body and intelligence development are bad, also easily induce major disease.And with the adjoint environmental problem of economic development and social competition companion
With life survival pressure problem, immunity of organisms, which declines, is increasingly becoming the big secret worry of modern.Modern medicine surface, the mankind
99% disease is all relevant with immune system.Therefore, strengthen the research block-regulations of immunity of organisms product has turned into important at present
Problem.
There is also the health food that some are directed to strengthen immunity, the health care food of traditional strengthen immunity on the market at present
Product be made of mostly the material for using some integration of drinking and medicinal herbs for raw material, but the most over emphasis of existing health food its
The chemical synthesis substance such as color, more or less addition pigment, essence, preservative, sweetener, cause health food has
The defects of effective component content is very low, and active ingredient be present and be not easy to be absorbed by organisms utilization, and health-care effect is undesirable.
The content of the invention
The defects of in order to overcome prior art, it is an object of the invention to provide a kind of albumen oligopeptide group of strengthen immunity
Compound, utilization can be quickly absorbed by organisms, the health-care effect with significant strengthen immunity.
Meanwhile the present invention also resides in the preparation method for providing a kind of oligomeric peptide combinations of the albumen of strengthen immunity.
In order to realize the above object the technical solution adopted in the present invention is：
A kind of oligomeric peptide combinations of the albumen of strengthen immunity, mainly by following weight percent dosage raw material prepare and
Into：Albumen oligopeptide 78~85%, ginseng extract 2~5%, vitamin C 0.3~0.6%, mineral element zinc 0.1~
0.3%th, mineral element selenium 0.01~0.03%.
In order to further lift the health-care effect of product strengthen immunity, it is preferred that mineral element zinc and the mineral member
The mass ratio of plain selenium is 10：1.
Preferably, the oligomeric peptide combinations of the albumen of above-mentioned strengthen immunity, mainly by the raw material of following weight percent dosage
It is prepared：Albumen oligopeptide 80%, ginseng extract 5%, vitamin C 0.5%, mineral element zinc 0.3%, mineral element
Selenium 0.03%.
Optionally, the oligomeric peptide combinations of the albumen are solid beverage；The raw material surplus is auxiliary material；The accessory package contains
10~12% sweetener.Except sweetener surplus is that often addition uses adjustment product entirety flavor in solid beverage in auxiliary material
And/or extend the additive of shelf life of products, such as essence, preservative.
Preferably, the albumen oligopeptide solid beverage of above-mentioned strengthen immunity, by the raw material system of following weight percent dosage
It is standby to form：Albumen oligopeptide 80%, ginseng extract 5%, vitamin C 0.5%, mineral element zinc 0.3%, mineral element selenium
0.03%, surplus is auxiliary material；The accessory package contains 10% sweetener.
Optionally, the sweetener is in oligoisomaltose, inulin, FOS, stevioside, neotame and Sucralose
One kind or any combination.
Optionally, the albumen oligopeptide is soy protein oligopeptide.The soy protein oligopeptide mean molecule quantity is
1000Da, prepared by soybean protein by enzymolysis or acid-hydrolyzed mode.
The source of the mineral element zinc is zinc lactate and/or zinc citrate)；The source of the mineral element selenium is sub- selenium
Sour selenium and/or Se-enriched yeast.
The preparation method of the albumen oligopeptide solid beverage of above-mentioned strengthen immunity, including take each original of form of powdery particles
Material, it is well mixed, that is, completes.
Above-mentioned albumen oligopeptide solid beverage directly uses mixing in water for oral taking.
Albumen oligopeptide has immune resurrection function, after 7 peptide and 9 peptides therein enter human body, prompted with the antigen of human body
Immune genetic factor IQ antigen interactions on cell, are activated T cell B cell, produce globulin E, globulin E immediately
Combined with anaphylactin, make anaphylactin ineffective, while produce immune antiboidy, bring back to life immunologic function, play the immune work(of enhancing
The effect of energy.
Ginsenoside (ginsenosides) is the most important active ingredient in Chemical Constituents of Panax Ginseng, present Analyze ＆ separate
The ginsenoside monomer gone out is very more, and its quantity reaches kind more than 50.Ginsenoside can be to body metabolism, immune system, interior
Excretory system and anti-oxidation stress system produce important function, show very strong pharmacological action.Meanwhile panaxan is right
Body is hypoglycemic and raising immunity of organisms aspect shows powerful pharmacological action.
Vitamin C can strengthen the chemotaxis and deformability of neutrophil leucocyte, improve sterilizing ability, promote lymphoblast
Generation, improve body to external and malignant cell identification and killing, participate in the synthesis of immunoglobulin.
Zinc is the important element for participating in immunologic function, and appropriate zinc can promote the hair of immune organ (marrow, thymus gland, spleen)
Educate and perfect in shape and function, there is nutrition and regulation to immunologic function, in microelement deficiencies, zinc deficiency is easiest to cause
Immunologic function is destroyed so that undertaking the metabolic activity of the lymphoid tissue of immunologic function reduces.
Trace element necessary to selenium is a kind of people's ratio, its critical function is except adjusting immunity, including cellular immunity and body
Liquid is immunized, also oxidation resistant effect.It is demonstrated experimentally that mouse immuning ball protein G level of the feeding containing selenium is significantly raised.
The oligomeric peptide combinations of albumen of strengthen immunity of the present invention, with albumen oligopeptide, ginseng extract, vitamin C, ore deposit
Thing element zinc and mineral element selenium are prepared for active ingredient raw materials.The wherein oligomeric peptide molecular weight of albumen is small, amino acid composition
It is complete, be a kind of mixture of the small-molecular peptides based on 7~8 amino acid chains, can quickly, be completely absorbed by organisms profit
With for body while quickly albumen oligopeptide is absorbed, albumen oligopeptide carries ginseng extract, vitamin C, mineral member
Plain zinc and mineral element selenium is absorbed by organisms, and acts on cell, lifts absorption rate of the body to other raw materials, while each original
Material produces synergistic function, health-care efficacy of the lifting product to immunity of organisms in the amount ranges of restriction.
The preparation method of the oligomeric peptide combinations of albumen of strengthen immunity of the present invention, using it is simple it is dry-mixed by the way of prepare
It is easy to operate into solid beverage, it is easily controllable, suitable for industrial application.
Embodiment
Technical scheme is described in detail below by specific embodiment.
In the auxiliary material used in following embodiments in addition to comprising sweetener, surplus horn of plenty product special flavour and extension
The additive component of shelf-life, such as essence, preservative；
Albumen oligopeptide is soy protein oligopeptide in following embodiments, mean molecule quantity 1000Da, by soybean protein
Prepared by enzymolysis or acid-hydrolyzed mode.
Embodiment 1
A kind of albumen oligopeptide solid beverage of strengthen immunity, is prepared by the raw material of following weight percent dosage：
Albumen oligopeptide 80%, ginseng extract 5%, vitamin C 0.5%, mineral element zinc 0.3%, mineral element selenium 0.03%,
Surplus is auxiliary material；Oligoisomaltose 10% is included wherein in auxiliary material.
The source of wherein described mineral element zinc is zinc lactate；The source of the mineral element selenium is selenous acid selenium.
The preparation method of the albumen oligopeptide solid beverage of the present embodiment strengthen immunity, including take each of form of powdery particles
Raw material, it is well mixed, that is, completes.
Embodiment 2
A kind of albumen oligopeptide solid beverage of strengthen immunity, is prepared by the raw material of following weight percent dosage：
Albumen oligopeptide 78%, ginseng extract 3.5%, vitamin C 0.3%, mineral element zinc 0.1%, mineral element selenium
0.01%, surplus is auxiliary material；Inulin 12% is included wherein in auxiliary material.
The source of wherein described mineral element zinc is zinc citrate；The source of the mineral element selenium is Se-enriched yeast.
The preparation method of the albumen oligopeptide solid beverage of the present embodiment strengthen immunity, including take each of form of powdery particles
Raw material, it is well mixed, that is, completes.
Embodiment 3
A kind of albumen oligopeptide solid beverage of strengthen immunity, is prepared by the raw material of following weight percent dosage：
Albumen oligopeptide 85%, ginseng extract 2%, vitamin C 0.6%, mineral element zinc 0.2%, mineral element selenium 0.02%,
Surplus is auxiliary material；FOS 11% is included wherein in auxiliary material.
The source of wherein described mineral element zinc is zinc lactate and zinc citrate；The source of the mineral element selenium is sub- selenium
Sour selenium and Se-enriched yeast.
The preparation method of the albumen oligopeptide solid beverage of the present embodiment strengthen immunity, including take each of form of powdery particles
Raw material, it is well mixed, that is, completes.
Comparative example 1
The albumen oligopeptide solid beverage of this comparative example strengthen immunity, as different from Example 1, it is oligomeric to save deproteinized
Peptide, soybean protein 80%, other are the same as embodiment 1.
Comparative example 2
The albumen oligopeptide solid beverage of this comparative example strengthen immunity, as different from Example 1, saves mineral element
Selenium, the dosage of adjustment mineral element zinc is 0.33%.
Comparative example 3
The albumen oligopeptide solid beverage of this comparative example strengthen immunity, as different from Example 1, save ginseng extraction
Thing, the dosage of adjustment albumen oligopeptide is 85%.
Comparative example 4
The albumen oligopeptide solid beverage of this comparative example strengthen immunity, as different from Example 1, saves vitamin C,
The dosage for adjusting albumen oligopeptide is 80.3%.
Test example
1st, general information
Choose the patient 200 that clinical manifestation in 25~35 years old is fatigable hypoimmunity；Choose 25~40 years old clinic
Show as the patient 200 of the hypoimmunity of easy catching a cold；Choose 25~40 years old chemicotherapy patient 200；Choose clinical manifestation
For the elderly 200 of 60~70 years old of the hypoimmunity symptom such as fatiguability, the state of mind be bad.
2nd, diagnostic criteria
Fatiguability improvement standard：After daily sleep 8~9 hours, can continue daytime 4~5 hours it is reactionless blunt, thermophilic
The phenomenon slept, it is designated as effectively；Continue 2~4 hours reactionless blunt, drowsiness phenomenons, be designated as effective；It is slow to fatigable reaction
What the clinical manifestation such as blunt, drowsiness was not improved, it is invalid to be designated as；
Easy catching a cold improvement standard：Flu occurrence frequency reduction by more than 50% is designated as effectively；Occurrence frequency of catching a cold reduces by 10
~50% be designated as is effective；Flu occurrence frequency reduce less than 10% be designated as it is invalid；
The elderly's improvement standard：What sleep quality, the state of mind and appetite were substantially improved, it is designated as effectively；Sleep matter
What amount, the state of mind and appetite slightly improved is designated as effective；What sleep quality, the state of mind and appetite were not improved is designated as nothing
Effect；
Chemicotherapy patient's improvement standard：What sleep quality, the state of mind and appetite were substantially improved, it is designated as effectively；Sleep
What dormancy quality, the state of mind and appetite slightly improved is designated as effective；The note that sleep quality, the state of mind and appetite are not improved
To be invalid.
3rd, usage and dosage：
The patient of every kind of illness is randomly divided into five groups, every group 40, one group of solid beverage for taking the preparation of embodiment 1, and one
Group takes the solid beverage of the preparation of comparative example 1, one group of solid beverage for taking the preparation of comparative example 2, takes comparative example 3 for one group and prepares
Solid beverage, one group of solid beverage for taking the preparation of comparative example 4, every morning and afternoon with mixing in water for oral taking solid beverage 15~
20g, persistently take 3 months, statistics effective percentage and obvious effective rate are as a result as shown in table 1 below：
Table 1
Had by improvement of the above-mentioned results showed that for the clinical disease of fatiguability, easy catching a cold, the elderly and chemicotherapy
Efficiency and total effective rate, be that embodiment 1 is substantially better than comparative example 1~4, it can be seen that, albumen oligopeptide, ginseng extract,
Synergistic function between vitamin C, mineral element zinc, mineral element selenium be present, improve the health care effect of product strengthen immunity
Fruit.
The health-care effect of the solid beverage strengthen immunity prepared by verification experimental verification, embodiment 2~3 and the base of embodiment 1
This is equivalent.
The technical concepts and features of certain the various embodiments described above and test example only to illustrate the invention, it is ripe its object is to allow
Present disclosure can be understood and implement according to this by knowing the people of technique, and it is not intended to limit the scope of the present invention.
The modification that all Spirit Essences according to main technical schemes of the present invention are done, should all cover within protection scope of the present invention.
Claims (10)
1. a kind of oligomeric peptide combinations of the albumen of strengthen immunity, it is characterised in that mainly by the original of following weight percent dosage
Material is prepared：Albumen oligopeptide 78~85%, ginseng extract 2~5%, vitamin C 0.3~0.6%, mineral element zinc
0.1~0.3%, mineral element selenium 0.01~0.03%.
2. the oligomeric peptide combinations of the albumen of strengthen immunity as claimed in claim 1, it is characterised in that mainly by following weight
The raw material of percentage amount is prepared：Albumen oligopeptide 80%, ginseng extract 5%, vitamin C 0.5%, mineral element zinc
0.3%th, mineral element selenium 0.03%.
3. the oligomeric peptide combinations of the albumen of strengthen immunity as claimed in claim 1, it is characterised in that the albumen oligopeptide
Composition is solid beverage；The raw material surplus is auxiliary material；The accessory package contains 10~12% sweetener.
4. the oligomeric peptide combinations of the albumen of strengthen immunity as claimed in claim 3, it is characterised in that by following weight percent
The raw material of dosage is prepared：Albumen oligopeptide 80%, ginseng extract 5%, vitamin C 0.5%, mineral element zinc
0.3%th, mineral element selenium 0.03%, surplus are auxiliary material；The accessory package contains 10% sweetener.
5. the oligomeric peptide combinations of the albumen of the strengthen immunity as described in claim 3 or 4, it is characterised in that the sweetener
For one kind or any combination in oligoisomaltose, inulin, FOS, stevioside, neotame and Sucralose.
6. the oligomeric peptide combinations of the albumen of the strengthen immunity as described in any one of Claims 1 to 4, it is characterised in that described
Albumen oligopeptide is soy protein oligopeptide.
7. the oligomeric peptide combinations of the albumen of strengthen immunity as claimed in claim 6, it is characterised in that the soybean protein is low
Poly- peptide mean molecule quantity is 1000Da, is prepared by soybean protein by enzymolysis or acid-hydrolyzed mode.
8. the oligomeric peptide combinations of the albumen of the strengthen immunity as described in any one of Claims 1 to 4, it is characterised in that described
The mass ratio of mineral element zinc and mineral element selenium is 10：1.
9. the oligomeric peptide combinations of the albumen of the strengthen immunity as described in any one of Claims 1 to 4, it is characterised in that described
The source of mineral element zinc is zinc lactate and/or zinc citrate；The source of the mineral element selenium is selenous acid selenium and/or selenium-rich
Yeast.
10. a kind of preparation method of the oligomeric peptide combinations of albumen of strengthen immunity as described in any one of Claims 1 to 4,
It is characterised in that it includes taking each raw material of form of powdery particles, it is well mixed, that is, completes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710695204.5A CN107518413A (en) | 2017-08-15 | 2017-08-15 | A kind of oligomeric peptide combinations of the albumen of strengthen immunity and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710695204.5A CN107518413A (en) | 2017-08-15 | 2017-08-15 | A kind of oligomeric peptide combinations of the albumen of strengthen immunity and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107518413A true CN107518413A (en) | 2017-12-29 |
Family
ID=60681182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710695204.5A Pending CN107518413A (en) | 2017-08-15 | 2017-08-15 | A kind of oligomeric peptide combinations of the albumen of strengthen immunity and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107518413A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109329948A (en) * | 2018-12-05 | 2019-02-15 | 北京斯利安药业有限公司 | A kind of composition and its application with strengthen immunity function |
| CN113040392A (en) * | 2021-03-12 | 2021-06-29 | 广州市金龟寿药品有限公司 | Composite preparation containing ovalbumin peptide |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103478716A (en) * | 2013-09-23 | 2014-01-01 | 南昌大学 | Preparation method for functional food with immunity enhancing effect |
| CN104082720A (en) * | 2014-06-10 | 2014-10-08 | 胡安然 | Micro-ecologic special diet for melanoma patients |
| CN104187686A (en) * | 2014-09-26 | 2014-12-10 | 洛阳华以生物工程有限公司 | Health product for improving immunity |
| CN106723084A (en) * | 2017-01-24 | 2017-05-31 | 山东中稷康特医食品有限公司 | Soybean oligopeptide drink and preparation method and the application in spy doctor's formula food |
| CN106880054A (en) * | 2017-03-06 | 2017-06-23 | 青岛海大华旗生物科技有限公司 | A kind of health food for preventing and treating muscular dystrophy and preparation method thereof |
| CN106889619A (en) * | 2017-03-06 | 2017-06-27 | 青岛海大华旗生物科技有限公司 | It is a kind of to promote health food of post-operative recovery and preparation method thereof |
| CN106912962A (en) * | 2017-03-16 | 2017-07-04 | 海门元生医学科技发展有限公司 | A kind of health food for lifting the Health Status of Elders and preparation method thereof |
-
2017
- 2017-08-15 CN CN201710695204.5A patent/CN107518413A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103478716A (en) * | 2013-09-23 | 2014-01-01 | 南昌大学 | Preparation method for functional food with immunity enhancing effect |
| CN104082720A (en) * | 2014-06-10 | 2014-10-08 | 胡安然 | Micro-ecologic special diet for melanoma patients |
| CN104187686A (en) * | 2014-09-26 | 2014-12-10 | 洛阳华以生物工程有限公司 | Health product for improving immunity |
| CN106723084A (en) * | 2017-01-24 | 2017-05-31 | 山东中稷康特医食品有限公司 | Soybean oligopeptide drink and preparation method and the application in spy doctor's formula food |
| CN106880054A (en) * | 2017-03-06 | 2017-06-23 | 青岛海大华旗生物科技有限公司 | A kind of health food for preventing and treating muscular dystrophy and preparation method thereof |
| CN106889619A (en) * | 2017-03-06 | 2017-06-27 | 青岛海大华旗生物科技有限公司 | It is a kind of to promote health food of post-operative recovery and preparation method thereof |
| CN106912962A (en) * | 2017-03-16 | 2017-07-04 | 海门元生医学科技发展有限公司 | A kind of health food for lifting the Health Status of Elders and preparation method thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109329948A (en) * | 2018-12-05 | 2019-02-15 | 北京斯利安药业有限公司 | A kind of composition and its application with strengthen immunity function |
| CN109329948B (en) * | 2018-12-05 | 2022-04-01 | 北京斯利安药业有限公司 | Composition with function of enhancing immunity and application thereof |
| CN113040392A (en) * | 2021-03-12 | 2021-06-29 | 广州市金龟寿药品有限公司 | Composite preparation containing ovalbumin peptide |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107668459A (en) | A kind of solid beverage of mushroom small-molecular peptides compounding and preparation method thereof | |
| CN102429235A (en) | Health care food with functions of relieving physical fatigue and enhancing immunity | |
| CN102757880A (en) | Maca health-care wine and preparation method thereof | |
| CN104783185B (en) | It is a kind of that there is strengthen immunity, health food of function of physical fatigue alleviation and preparation method thereof | |
| CN107518413A (en) | A kind of oligomeric peptide combinations of the albumen of strengthen immunity and preparation method thereof | |
| CN103340291A (en) | Chinese herbal feed modifier for improving meat quality of livestock and poultry and quality of fresh eggs | |
| Miura et al. | Basic and clinical studies on active hexose correlated compound | |
| CN105851185A (en) | Biscuit having anti-fatigue efficacy and preparation method thereof | |
| CN1150910C (en) | Bee pollen instant granule and its preparation method | |
| WO2016141775A1 (en) | Uses of jilin ginseng oligopeptide in preparing food product or healthcare food product for combating fatigue | |
| CN106820136A (en) | It is a kind of to improve the health care of sleep composition of quality and preparation method thereof | |
| JP5329307B2 (en) | Antiallergic composition | |
| CN108450962A (en) | A kind of solid beverage and preparation method thereof for Woman health | |
| CN109294848A (en) | A kind of active bio nanometer selenium wine and preparation method thereof | |
| CN101637490A (en) | Traditional Chinese medicine for reducing blood pressure, degrading fat, protecting liver and heart, preventing cancer and resisting ageing | |
| CN108813637A (en) | A kind of glutathione oral solution and preparation method thereof | |
| CN109172803A (en) | A kind of hydrogen-rich Chinese medicine composition for relieving the effect of alcohol, food, health food, hydrogen-rich drunk-sobering tablet and preparation method thereof | |
| CN106880054A (en) | A kind of health food for preventing and treating muscular dystrophy and preparation method thereof | |
| JP2008154488A (en) | Natural immunity functional food and drink | |
| CN1313112C (en) | Medicinal composition with nourishing and tranquilizing | |
| CN105876008A (en) | Health-care liquid tea drink | |
| CN105010975A (en) | Qi and kidney tonifying coarse grain powder and preparation method of the qi and kidney tonifying coarse grain powder | |
| CN109528704A (en) | A kind of composition of strengthen immunity and its preparing the application in medicament for immunity enhancement and health food | |
| US20130059035A1 (en) | Capsaicin composition and method related thereto | |
| CN104473283A (en) | Rose-ginger vinegar beverage and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171229 |
|
| RJ01 | Rejection of invention patent application after publication |