CN107509907A - A kind of solid beverage with preventing alcoholic liver injury - Google Patents
A kind of solid beverage with preventing alcoholic liver injury Download PDFInfo
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- CN107509907A CN107509907A CN201710971623.7A CN201710971623A CN107509907A CN 107509907 A CN107509907 A CN 107509907A CN 201710971623 A CN201710971623 A CN 201710971623A CN 107509907 A CN107509907 A CN 107509907A
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- liver injury
- alcoholic liver
- solid beverage
- liver
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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Abstract
The present invention is a kind of solid beverage with preventing alcoholic liver injury, and in terms of mass fraction, its active ingredient includes:2 50 parts of elaeagnus mollis leaf extract, 20 40 parts of lucidum spore powder, 1 10 parts of soybean lecithin, 1 10 parts of kudzu root extract, 2 20 parts of wolfberry fruit extract, 1 10 parts of allicin, 10 50 parts of polypeptide, 01 parts of vitamin A, 01 parts of vitamin E, 2 18 parts of Fruit powder, 20 50 parts of maltodextrin etc..This formula is formulated by pure plant extraction, other several components are combined on the basis of elaeagnus mollis leaf extract as active ingredient, can significant preventing alcoholic liver injury, while also there is protect liver, regulation blood fat, anti-oxidant, immunological regulation, the effect such as skin moisture-keeping.
Description
Technical field
The invention belongs to health care technology field, it is related to solid beverage and its preparation side of a kind of preventing alcoholic liver injury
Method.
Background technology
Alcoholic liver injury is due to liver diseases caused by long-term heavy drinking.Initial stage is usually expressed as fatty liver, enters
And alcoholic hepatitis, liver fibrosis and hepatic sclerosis can be developed into.It is one of common liver diseases in China, seriously endangers the people and be good for
Health.AML accounts for the ratio of same period hepatopathy inpatient and constantly risen in recent years, and 4.2% from 1991 increases to 1996
The 21.3% of year;Alcoholic cirrhosis rises to from 10.8% in 1999 24.0% in 2003 in the constituent ratio of causes of hepatic sclerosis.
Alcoholic liver injury key is being prevented, and mainly strengthens individual constitution, the generation improved resistance, accelerate chemical toxicant
Thank to removing toxic substances with relieving the effect of alcohol.
The content of the invention
Present invention solves the problem in that a kind of solid beverage of preventing alcoholic liver injury and preparation method thereof is provided,
It is formulated by pure plant extracts, without any toxicity and side effects, while preventing alcoholic liver injury, there is protect liver, immune tune
The effects such as section, regulation blood fat, anti-oxidant, skin moisture-keeping.
The present invention is to be achieved through the following technical solutions:
A kind of solid beverage with preventing alcoholic liver injury, it is characterised in that in terms of mass fraction, its active ingredient bag
Include:Elaeagnus mollis leaf extract 2-50 parts, lucidum spore powder 20-40 parts, soybean lecithin 1-10 parts, kudzu root extract 1-10
Part, wolfberry fruit extract 2-20 parts, allicin 1-10 parts, polypeptide 10-50 parts, vitamin A 0-1 parts, vitamin E 0-1 parts, fruit
Two kinds or any several in powder 2-18 parts, maltodextrin 20-50 parts.
A kind of preparation method of the solid beverage with preventing alcoholic liver injury, comprises the following steps:Will be described effective
The method that composition progressively increases by equivalent is well mixed, and is dispensed, labeling, stamp.
Elaeagnus mollis leaf extract, contain flavone compound, alkaloid, triterpenes, sterol and polysaccharide.With regulation blood
Fat, relieving asthma, cough-relieving, antibacterial, anti-inflammatory, the effect such as hypoglycemic.
Lucidum spore powder is the seed of ganoderma lucidum, is the part of ganoderma lucidum most elite, and 100 kairine sesames can just be collected into 1 gram of spore
Powder, pure lucidum spore powder is extremely precious, and rich in abundant polysaccharide, triterpene, alkaloid, vitamin etc., it has lucidum spore powder
The species and content of effect composition are significantly larger than ganoderma lucidum fruitbody, and lucidum spore powder is suppressing tumour, liver protecting, strengthened the body resistance to consolidate the constitution
The effect of aspect 75 times equivalent to ganoderma lucidum fruitbody.
Growth, development, immunological regulation and the metabolism of peptide major control human body, it is in a kind of equilibrium-like in human body
State, if after active peptide is reduced, important change occurs for the function of human body, to adult or the elderly, after lacking active peptide, itself
Immunity will decline, metabolic disturbance, endocrinopathy, the generation to give rise to diseases, such as insomnia, lean body mass or floating
It is swollen.Because active peptide also acts on nervous system, therefore human body will become slow movement, and brains is no longer wise, main
It is that active peptide is reduced, directly causes each position of human body to engender comprehensive aging, trigger various diseases.
Particularly, maize oligopeptide has sobering-up functions, exactly because it contains a high proportion of alanine and leucine.Human body
After taking in maize oligopeptide, by improving the concentration of alanine and leucine in blood, stable decomposition ethanol can be produced
Codehydrogenase, strengthen the activity of L-AD and acetaldehyde dehydrogenase, promote the decomposition and metabolism of internal ethanol, so as to
The concentration of ethanol in blood is reduced, has the function that to reduce drunk degree and sobers up.Contain what is enriched in maize oligopeptide simultaneously
Glutamic acid, intake maize oligopeptide can be in supplemental bloods because being suppressed and the amino acid of reduction by alcohol, so as to maintain brain cell
Energy supply and nervous activity, reduce alcohol caused by uncomfortable symptom.Wheat oligopeptide has strengthen immunity, protection
The ability of stomach lining.Samara protein peptides have protect liver, adjust the ability of immunity.Collagen peptide has skin care, light spot
Deng effect.
Lecithin has the function that protect liver, and heavy drinking or overnutrition can aggravate the burden of liver cell, reduce liver
The ability of synthetic phospholipid.When phosphatidyl choline deficiency in human body, a large amount of accumulations of the fat in liver can be caused, form fatty liver,
Liver cell is destroyed, hypofunction of liver, causes hepatic sclerosis even liver cancer.Science proves:It is thin that benefit food lecithin can strengthen liver
Born of the same parents' metabolism, promote fat acid decomposition, protect the generation of the illness such as liver, prevention fatty liver.Lecithin has phase with vitamin E
The auxiliary effect of coordinating, can strengthen antioxidation activity.
The root of kudzu vine has the power of regeneration for improving liver cell, recovers normal liver function, promotes choleresis, prevents fat from existing
Liver is accumulated, and can enhance metabolism, and strengthens liver detoxification function, prevents damage of the alcohol to liver.
Matrimony vine:《Sheng Nong's herbal classic》Start, just have structure Qi in the record of " nourishing liver and kidney ", materials for improving vision strengthening the essence, protection liver,
Improve hematopoiesis function.The fruit of Chinese wolfberry is particularly good at improving eyesight, so being commonly called as " bright eye ".Ancient Chinese medicine doctor treatment deficiency of liver-blood, kidney yin are lost
Eyesight caused by void is dim-sighted and yctalopia, is also usually raised using the fruit of Chinese wolfberry.
Allicin is to serum Qian caused by Carbon Tetrachloride Induced Liver Damage in Rats and malondialdehyde horizontal
Rise has obvious inhibitory action, and this effect has dose-effect relationship.Allicin can anti-lipid peroxidation thing to film knot
The damage of structure.It can dose-dependently prevent GSH exhaustion and GST in murine liver tissue to decline, increase liver cell GSH-PX activity
The activity of s- transferases, increase the combination function of detoxification of liver, so as to be shielded to liver or even whole body.Allicin
Can be by improving the level of liver cyclic adenosine monophosphate, regulating lipid metabolism, film transhipment and cell propagation, and increase the activity of enzyme, make
Blood fat hydrolysis increase, biosynthesis reduce, and increase the excretion of lipid composition, maintain serum, liver, kidney fat egg from and triglycerides
In normal range (NR), so as to prevent and treat fatty liver.
Compared with prior art, the present invention has beneficial below have the technical effect that:It is formulated by pure plant extracts,
Without any toxicity and side effects, while preventing alcoholic liver injury, there is protect liver, immunological regulation, anti-oxidant, skin moisture-keeping etc. to make
With.The maintenance after the formation and hepatic injury of hepatic injury is intervened simultaneously.Soybean lecithin is reduced and reduced fatty in liver
Accumulation.Kudzu root extract promotes choleresis, promotes fat metabolism.Allicin adds the synthesis detoxification ability of liver, matrimony vine
It is nourishing liver and kidney.This formula reduces the burden of liver, while protect liver, addition samara extract, lucidum spore powder and polypeptide, and antioxygen
The immunity of liver itself, omnibearing protection liver are improved while change.
Brief description of the drawings
Fig. 1 is original body mass table;
Fig. 2 is initial cholesterol table
Fig. 3 is homogeneity test of variance result schematic diagram;
Fig. 4 is histological score result schematic diagram.
Embodiment
Embodiment 1:
A kind of solid beverage with preventing alcoholic liver injury, it is characterised in that in terms of mass fraction, its active ingredient bag
Include:2 parts of elaeagnus mollis leaf extract, 20 parts of lucidum spore powder, 10 parts of soybean lecithin, 10 parts of kudzu root extract, allicin 1
Part, 15 parts of samara protein peptides, 15 parts of maize oligopeptide, 1 part of vitamin A, 1 part of vitamin E, 2 parts of Fruit powder, maltodextrin 23
Part.
Embodiment 2:
A kind of solid beverage with preventing alcoholic liver injury, it is characterised in that in terms of mass fraction, specifically, its is effective
Composition includes:50 parts of elaeagnus mollis leaf extract, 2 parts of wolfberry fruit extract, 1 part of allicin, 2 parts of collagen peptide, corn are oligomeric
8 parts of peptide, 1 part of vitamin A, 1 part of vitamin E, 15 parts of Fruit powder, 20 parts of maltodextrin.
Embodiment 3:
A kind of solid beverage with preventing alcoholic liver injury, it is characterised in that in terms of mass fraction, specifically, its is effective
Composition includes:20 parts of elaeagnus mollis leaf extract, 25 parts of lucidum spore powder, 5 parts of soybean lecithin, 5 parts of kudzu root extract, dimension life
Plain 0.5 part of A, 0.5 part of vitamin E, 5 parts of oat peptide, 14 parts of Fruit powder, 25 parts of maltodextrin.
Embodiment 4:
A kind of solid beverage with preventing alcoholic liver injury, it is characterised in that in terms of mass fraction, specifically, its is effective
Composition includes:30 parts of elaeagnus mollis leaf extract, 25 parts of lucidum spore powder, 3 parts of soybean lecithin, 6 parts of kudzu root extract, garlic
10 parts of element, 10 parts of wheat oligopeptide, 0.1 part of vitamin E, 5.9 parts of Fruit powder, 10 parts of maltodextrin.
Embodiment 5:
A kind of solid beverage with preventing alcoholic liver injury, it is characterised in that in terms of mass fraction, specifically, its is effective
Composition includes:40 parts of elaeagnus mollis leaf extract, 27 parts of kudzu root extract, 8 parts of allicin, 25 parts of maize oligopeptide.
Embodiment 6:
A kind of solid beverage with preventing alcoholic liver injury, it is characterised in that in terms of mass fraction, specifically, its is effective
Composition includes:15 parts of elaeagnus mollis leaf extract, 30 parts of lucidum spore powder, 10 parts of kudzu root extract, 10 parts of allicin, corn are low
Poly- 35 parts of peptide.
Efficacy experiments method:
1st, according to initial cholesterol and original body mass, according to the principle being grouped at random, experimental rat is divided into 8 groups, is respectively sky
White group, model group, formula group 1, formula group 2, formula group 3, formula group 4, formula group 5, formula group 6 every group 10.Variance analysis
As a result indifference between each group is shown.It the results are shown in Table 1,2.
Drawn in table 1, homogeneity test result is shown, P=0.141>0.05, indifference in explanation group.The results of analysis of variance
(P=0.976), indifference between group.
Drawn in table 2, homogeneity test result:P=0.216>0.05, explanation group is interior, and there was no significant difference.Variance analysis knot
Fruit(P=1.000), indifference between group.
2nd, bilirubin compares:Homogeneity test of variance finds that intra-class variance is uneven, therefore selects non-parametric test method.As a result
Show the 2nd group it is variant with remaining each group.As shown in figure 3,
3rd, histological score compares:As shown in figure 4, histological score represents that second group variant with remaining each group.
Shown according to above experimental result, six group of formula have protective effect to liver.
Claims (4)
- A kind of 1. solid beverage with preventing alcoholic liver injury, it is characterised in that in terms of mass fraction, its active ingredient bag Include:Elaeagnus mollis leaf extract 2-50 parts, lucidum spore powder 20-40 parts, soybean lecithin 1-10 parts, kudzu root extract 1-10 Part, wolfberry fruit extract 2-20 parts, allicin 1-10 parts, polypeptide 10-50 parts, vitamin A 0-1 parts, vitamin E 0-1 parts, fruit Two or more in powder 2-18 parts, maltodextrin 20-50.
- 2. a kind of solid beverage with preventing alcoholic liver injury according to claim 1, wherein elaeagnus mollis leaf carry The active ingredient in thing is taken to include 4'-O-methylepigallocatechin, 4'-O-methygallocatechin, β-paddy Sterol, arjunolic acid, hippophamide, caffeic acid, daucosterol, methyl linoleate, Kaempferol -7-O- α-L- rhamnoses One or more in glycosides, Kaempferol -3-O- α-L- arabopyranose glycosides -7-O- alpha-L-rhamnosides.
- 3. a kind of solid beverage with preventing alcoholic liver injury according to claim 1, wherein polypeptide include:Soybean One or more in peptide, oat peptide, collagen peptide, maize oligopeptide, wheat oligopeptide, samara protein peptides.
- 4. a kind of solid beverage with preventing alcoholic liver injury according to claim 1, wherein allicin is garlic Extract.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108477367A (en) * | 2017-08-01 | 2018-09-04 | 楼良水 | The cordyceps sinensis oligopeptide pressed candy of Soboring-up liver-protecting |
CN115474642A (en) * | 2021-06-16 | 2022-12-16 | 安阳鲜宝食品科技有限公司 | Tablet candy added with novel poly-mixed peptide and having liver protecting and sobering effects and preparation method thereof |
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CN101874857A (en) * | 2010-05-28 | 2010-11-03 | 劲牌有限公司 | Liver-protecting white spirit for resisting alcoholic liver injury and production process thereof |
CN102106876A (en) * | 2011-02-15 | 2011-06-29 | 赵军 | Preparation formula of novel alcohol-relieving capsules and preparation method |
CN103083429A (en) * | 2013-01-04 | 2013-05-08 | 山西师范大学 | Blood fat-reducing traditional Chinese medicine formula |
CN103211957A (en) * | 2013-05-02 | 2013-07-24 | 赵月 | Alcohol relieving and liver protecting composition and application thereof |
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CN101874857A (en) * | 2010-05-28 | 2010-11-03 | 劲牌有限公司 | Liver-protecting white spirit for resisting alcoholic liver injury and production process thereof |
CN102106876A (en) * | 2011-02-15 | 2011-06-29 | 赵军 | Preparation formula of novel alcohol-relieving capsules and preparation method |
CN103083429A (en) * | 2013-01-04 | 2013-05-08 | 山西师范大学 | Blood fat-reducing traditional Chinese medicine formula |
CN103211957A (en) * | 2013-05-02 | 2013-07-24 | 赵月 | Alcohol relieving and liver protecting composition and application thereof |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108477367A (en) * | 2017-08-01 | 2018-09-04 | 楼良水 | The cordyceps sinensis oligopeptide pressed candy of Soboring-up liver-protecting |
CN115474642A (en) * | 2021-06-16 | 2022-12-16 | 安阳鲜宝食品科技有限公司 | Tablet candy added with novel poly-mixed peptide and having liver protecting and sobering effects and preparation method thereof |
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