CN107496243A - A kind of antibacterial plant residue composition and its application - Google Patents
A kind of antibacterial plant residue composition and its application Download PDFInfo
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- CN107496243A CN107496243A CN201710825839.2A CN201710825839A CN107496243A CN 107496243 A CN107496243 A CN 107496243A CN 201710825839 A CN201710825839 A CN 201710825839A CN 107496243 A CN107496243 A CN 107496243A
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- Prior art keywords
- slag
- extraction
- antibacterial
- centella
- residue composition
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
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- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a kind of antibacterial plant residue composition and its application.Said composition is made up of the component of following mass percent：Radix scutellariae extraction slag 0.3 1.0%, giant knotweed extraction slag 0.2 0.8%, centella extraction slag 0.5 1.2%.It is applied in hand cleanser, releived with anti-inflammatory, antibacterial, antiallergic and other effects, it is a kind of gentle non-stimulated, natural plants hand cleanser.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of antibacterial plant residue composition and its application.
Background technology
With the raising of people's living standard and quality of life, people propose higher requirement to hand-washing article.Past,
Because perfumed soap has a good dirt-removing power, people use perfumed soap as hand-washing article always, still, due to perfumed soap when in use
Easily slide, meet water and high temperature and can soften and consume naturally, and perfumed soap is in alkalescence, wash rear skin easily dry, tarnish, especially
Dirt and bacterium on hand is easily infected with, turns into pollution source, causes people to start not using perfumed soap in public places.Due to
Hand cleanser has moderate performance, easy to use, sanitation and hygiene and it is easily stored the advantages of, gradually instead of perfumed soap be widely used in house
Front yard and public place.
Commercially available hand cleanser mainly stresses antibacterial effect, be short of to wash rear both hands nursing, lack antiallergic and releive, improve hand
Portion's microcirculation etc. acts on, and causes both hands after washing one's hands drying, the phenomenon of decortication easily occur.Therefore, research and development one kind effectively plays
Anti-inflammatory, antibacterial, antiallergic are releived and other effects, and have the function of improving hand microcirculation, and nonirritant hand cleanser is current
Research direction.
The content of the invention
For prior art, it is an object of the invention to provide a kind of antibacterial plant residue composition and its application, the group
There is compound anti-inflammatory, antibacterial, antiallergic to releive and other effects.
To achieve the above object, the present invention provides following technical scheme：
A kind of antibacterial plant residue composition extracts slag by radix scutellariae, giant knotweed extracts slag and centella extraction slag forms, and yellow
A kind of reed mentioned in ancient books extraction slag, giant knotweed extraction slag, the mass ratio of centella extraction slag are (3-10)：(2-8)：(5-12).
Preferably, described radix scutellariae extraction slag, giant knotweed extraction slag, the mass percent of centella extraction slag are as follows：Radix scutellariae
Extract slag 0.3-1.0%, giant knotweed extraction slag 0.2-0.8%, centella extraction slag 0.5-1.2%.
A kind of antibacterial plant residue composition is prepared as follows：By radix scutellariae, giant knotweed, centella plant material by carrying
Take the residue after utilizing to be dried, be then comminuted into 10-20 mesh, finally mixed according to above-mentioned ratio.
Further, described plant material refers to radix scutellariae root, giant knotweed stem and root, centella herb.
Further, residue of the described plant material after extraction and application refer to plant material by alcohol extracting, water extraction,
Left residue after one or more techniques extraction in oil immersion formulation, supercritical carbon dioxide extraction method.
The present invention also provides a kind of antibacterial plant residue composition and is preparing the application of cosmetics, and the cosmetics are to wash one's hands
Liquid.
Further, described hand cleanser includes the component of following mass percent：Above-mentioned plant residue composition
1.0-3.0%, polyvinyl alcohol 2.0-8.0%, glycerine 2.5-9.6%, carboxymethyl cellulose 1.2-3.0%, methyl acrylate
0.8-1.6%, laureth sodium sulfovinate 0.2-0.7%, Cocoamidopropyl betaine 1.0-4.1%, dodecyl sulphur
Sour sodium 0.2-1.0%, Polyquaternium-10 0.1-0.4%, sodium hydroxide 0.1-0.5%, EDETATE SODIUM 0.01-0.05%, peroxide
Change dibenzoyl 0.1-0.5%, deionized water surplus.
Following introduce is made to the main composition of the present invention：
Radix scutellariae has heat-clearing and damp-drying drug, an effect of purging intense heat and detonicating, principle active component have scutelloside, wogonoside, baicalein and
Wogonin etc..Research shows that radix scutellariae and its active ingredient have extensive pharmacological action, as anti-inflammatory, it is anti-oxidant, antitumor and
Immunological regulation etc., it is especially the most notable with antibacterium, fungi effect.Radix scutellariae has a broad antifungal spectrum, its decoction is to a variety of gram positive bacterias, leather
The growth of blue negative bacterium and conveyor screw etc. has inhibitory action.Radix scutellariae also has antifungal activity, to Candida albicans, Xu Lanmao
The growth of a variety of pathogenic funguses such as tinea bacterium has certain inhibitory action.Scutelloside can suppress the activity of sulfydryl enzyme, so that yellow
A kind of reed mentioned in ancient books glycosides has the function that strong antihistamine and acetylcholine, can substantially reduce sensitized mice lung sections and chemistry during antigen-reactive
The release of medium, there is stronger antiallergic activity.Research has shown that baicalein has stronger antibacterial action, it may be possible to which radix scutellariae resists
The main component of bacterium effect.Baicalein is about 0.29mmol/L to the IC50 of Escherichia coli inhibitory action, and mechanism of action is probably
Inhibit ATP synzyme.Baicalein equally has inhibitory action, minimal inhibitory concentration to Fusarium oxysporum and Candida albicans
(MICs) it is respectively 112 and 264 μ g/mL.It is by suppressing Candida albicans biofilm that baicalein, which suppresses Candida albicans,
Formed, reduce mitochondrial membrane potential and induce Candida albicans dead.
Giant knotweed is the perennial shrub shape herbaceous plant of polygonaceae Polygonum, is used as medicine with dry rhizome and root.Its mildly bitter flavor, property are micro-
It is cold, Return liver, courage, lung channel, have normalizing gallbladder to cure jaundice, clearing heat and detoxicating, blood stasis removing analgesic, it is relieving cough and reducing sputum the effect of.Giant knotweed is a kind of important
Chinese medicine, there is the effect such as clearing heat and detoxicating, anti-bacteria and anti-virus.Mainly contained in giant knotweed Anthraquinones, flavonoids, class, phenols with
And the compound of some monosaccharides.Giant knotweed and its active ingredient have multiple pharmacological effect, including antibacterial, anti-inflammatory, antiviral, tune
Blood fat, antithrombotic, change lectin from hemolymph, expansion blood vessel, protection it is myocardium, anti-oxidant, antitumor, improve Alzheimer disease symptoms and
Prevent AIDS.With antibacterial activity, to staphylococcus aureus, pseudomonas aeruginosa, EHEC, hepatitis diplococcus
Etc. inhibited, while giant knotweed also has Immunologic Functions.
Centella be also known as collapse jorum, centella asiatica, Longtube Ground Ivy Herb, obcordate christia herb etc., be Umbelliferae Centella plant, it is widely distributed
The various regions on the south the Yangtze river basin, are the Guangdong conventional Chinese herbal medicines in area among the people, and China medically with centella external application and for oral administration cures the disease
Existing more than 2,000 years history.Centella is cold in nature, bitter, pungent, has the effect of clearing heat and promoting diuresis, promoting blood circulation and hemostasis, removing toxicity for detumescence.Herb
Master contains the compositions such as triterpenes, polyyne olefines, volatile oil.Clinic is used for jaundice with damp-heat pathogen, carbuncle sore tumefacting virus, traumatic injury, biography
Metachromia hepatitis, skin disease, meningococal meningitis etc..Centella water extract has antibacterial and antivirus action, to golden yellow Portugal
Grape coccus and proteus have bacteriostasis, to Pseudomonas aeruginosa, Escherichia coli, paracolon, S. sonnei, Fu Shi dysentery
Shigella and bacillus anthracis are without bacteriostasis.Also have resisting pathogenic microbes effect, regulation immune simultaneously and reduce blood glucose
Effect, antiinflammatory action, the effect of resisting hyperplasia of mammary glands, cooling effect.
Compared with prior art, it is the device have the advantages that as follows：(1) present invention mainly comprising giant knotweed extraction slag,
Radix scutellariae extraction slag, centella extraction slag.Giant knotweed extracts the effective active in slag and radix scutellariae extraction slag, is combined with protein, makes thin
The protein coagulating of intracellular, bacteriostasis is played by suppressing the activity of bacterial metabolism enzyme；Radix scutellariae extraction slag can also improve
The inhibitory action of formation to bacterial biof iotalm, immunocompetence can also be improved while centella extraction slag antibiotic effect, three
Kind extraction slag synergy, plays more effective antibiotic effect.(2) present invention is mainly special using also there being its raw material in residue
Some active components, the effect of synergy to reach antibacterial.These residues are effectively utilized, is turned waste into wealth, is reduced and be produced into
This, improves the utilization rate of plant material, while contribute to environmental protection.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated：
The hand cleanser embodiment 1~5 of the present invention is formulated, and is shown in Table 1.
Table 1
Plant residue composition is prepared as follows：
The residue of radix scutellariae, giant knotweed, centella plant material after extraction and application is dried, is then comminuted into 10-
20 mesh, finally mixed according to above-mentioned ratio.
Comparative example 1：
Radix scutellariae extraction slag is not added in difference with embodiment 3 only, and remaining each material addition, conditions and technology of preparation is not
Change.
Comparative example 2：
Giant knotweed extraction slag is not added in difference with embodiment 3 only, and remaining each material addition, conditions and technology of preparation is not
Change.
Comparative example 3：
Centella extraction slag is not added in difference with embodiment 3 only, remaining each material addition, and conditions and technology of preparation is equal
Do not change.
Comparative example 4：
Compared with Example 3, radix scutellariae extraction slag, giant knotweed extraction slag, centella extraction slag do not add, and remaining each material adds
Dosage, conditions and technology of preparation do not change still.
Antibiotic effect is verified：
This experiment is made to represent equal, participation this product group using staphylococcus aureus, Escherichia coli and propionibacterium acne
The bacteriostasis of compound.Filter paper is cut into the φ 5mm scraps of paper using card punch, by standby after high-temperature sterilization, then with clean
Sterilizing filter paper piece is respectively placed in the counter sample liquid that the configuration of each example or sterilized water forms by tweezers, is dried after soaking half an hour,
It is standby after mark.
Fixed with pipette and draw 0.1mL bacteria suspensions in sterile petri dish, pour into the sterilising medium of 15mL coolings,
, will be each after natural condensation and type of culture medium changes, the horizontal rest after culture medium fully mixes because corresponding strain is different
The individual scraps of paper are smooth in culture dish, are placed in very steady 37 DEG C of incubator and cultivate 1~2 day.Culture is unified after terminating to take out sample, and makes
Antibacterial circle diameter is determined with the ruler of unified standard, collects rear list, such as table 2
Table 2
As can be found from Table 2, basic hand sanitizer formula comparative example 4 has slight antibacterial ability, and its reason is that basis is matched somebody with somebody
Side has certain cleaning effect and concentration higher, can play extremely slight fungistatic effect, have no effect on other data.
The data of comparative example 1~3 are observed it is recognised that radix scutellariae extraction slag, giant knotweed extract slag, accumulated snow in the present composition
Grass extraction slag has antibacterial ability, when being used alone or mixing the basic hand cleanser of addition two-by-two, can produce certain antibacterial effect,
But unobvious.
From embodiment, if radix scutellariae is extracted into slag, giant knotweed extracts slag, centella extraction slag three is answered by certain proportion
It is added to after matching somebody with somebody in basic hand sanitizer formula, then antibacterial ability increases, and illustrates that there is the radix scutellariae of certain antibacterial ability to extract originally
After slag, giant knotweed extraction slag, centella extract slag component by compounding, acted synergistically, mutual gain other components resist
Bacterium acts on, therefore causes antibacterial effect more more preferable than comparative example.
Above example is merely to illustrate embodiment of the present invention, does not have any formal limit to the present invention
System；It is any to be engaged in professional and technical personnel, all have the ability using the technology contents having revealed that, some are made to it and changes or repaiies
Decorations, turn into the equivalent embodiment of equivalent variations.According to the technology of the present invention essence, simply modification, equivalent variations are carried out to the present invention
With modification, belong in the range of technical solution of the present invention.
Claims (9)
1. a kind of antibacterial plant residue composition, it is characterised in that described plant residue composition extracts slag, giant knotweed by radix scutellariae
Extract slag and centella extraction slag composition.
2. a kind of antibacterial residue composition according to claim 1, it is characterised in that described radix scutellariae extracts slag, giant knotweed
Extract slag, the mass ratio of centella extraction slag is (3-10)：(2-8)：(5-12).
A kind of 3. antibacterial plant residue composition according to claim 1 or 2, it is characterised in that described radix scutellariae extraction
Slag, giant knotweed extraction slag, the mass percent of centella extraction slag are as follows：Radix scutellariae extraction slag 0.3-1.0%, giant knotweed extraction slag 0.2-
0.8%th, centella extraction slag 0.5-1.2%.
A kind of 4. antibacterial plant residue composition according to claim any one of 1-3, it is characterised in that described plant
Residue composition is prepared as follows：The residue of radix scutellariae, giant knotweed, centella plant material after extraction and application is done
It is dry, 10-20 mesh is then comminuted into, is finally mixed according to above-mentioned ratio.
5. a kind of antibacterial plant residue composition according to claim 4, it is characterised in that described plant material refers to
Radix scutellariae root, giant knotweed stem and root, centella herb.
6. a kind of antibacterial plant residue composition according to claim 4, it is characterised in that described plant material passes through
Residue after extraction and application refers to plant material by one in alcohol extracting, water extraction, oil immersion formulation, supercritical carbon dioxide extraction method
Left residue after kind or kinds of processes extraction.
7. a kind of antibacterial plant residue composition according to claim any one of 1-6 is preparing the application of cosmetics.
8. application according to claim 7, it is characterised in that described cosmetics are hand cleanser.
9. a kind of hand cleanser, it is characterised in that described hand cleanser includes the component of following mass percent：Such as claim 1-
Plant residue composition 1.0-3.0%, polyvinyl alcohol 2.0-8.0%, glycerine 2.5-9.6%, carboxymethyl described in 6 any one is fine
Tie up plain 1.2-3.0%, methyl acrylate 0.8-1.6%, laureth sodium sulfovinate 0.2-0.7%, cocamidopropyl propyl amide sweet tea
Dish alkali 1.0-4.1%, lauryl sodium sulfate 0.2-1.0%, Polyquaternium-10 0.1-0.4%, sodium hydroxide 0.1-0.5%,
EDETATE SODIUM 0.01-0.05%, dibenzoyl peroxide 0.1-0.5%, deionized water surplus.
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|---|---|---|---|
| CN201710825839.2A CN107496243A (en) | 2017-09-13 | 2017-09-13 | A kind of antibacterial plant residue composition and its application |
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| CN201710825839.2A CN107496243A (en) | 2017-09-13 | 2017-09-13 | A kind of antibacterial plant residue composition and its application |
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| CN107496243A true CN107496243A (en) | 2017-12-22 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112137921A (en) * | 2019-06-27 | 2020-12-29 | 东莞圣幸健康科技有限公司 | Soothing and anti-allergy composition, application thereof and soothing and anti-allergy mask |
-
2017
- 2017-09-13 CN CN201710825839.2A patent/CN107496243A/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112137921A (en) * | 2019-06-27 | 2020-12-29 | 东莞圣幸健康科技有限公司 | Soothing and anti-allergy composition, application thereof and soothing and anti-allergy mask |
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Application publication date: 20171222 |