CN107456481A - A kind of Chinese medicine composition for treating coronary disease and angina pectoris and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating coronary disease and angina pectoris and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition for treating coronary disease and angina pectoris, mainly it is made up of Chinese medicine pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum of raw material, is according to parts by weight：100 380 parts of pseudo-ginseng, 350 650 parts of the red sage root, 50 200 parts of American Ginseng, 5 80 parts of ganoderma lucidum.The invention also discloses a kind of preparation method for the Chinese medicine composition for treating coronary disease and angina pectoris.The present invention is according to the dialectical theory of the traditional Chinese medical science, complete square reasonable compatibility, using pseudo-ginseng as monarch drug in a prescription；Using the red sage root as ministerial drug, using American Ginseng, ganoderma lucidum as adjutant, from chest qi, it is promoting blood circulation and removing blood stasis, remove obstruction in channels to relieve pain and start with, while emphasize nourishing Yin and clearing heat, diuresis defaecation, human body is subjected to overall dialectical conditioning and treatment, so as to reach the purpose for thoroughly curing coronary heart diseases and angina pectoris.The traditional Chinese medicine composite of the present invention is simple and easy to get, cheap, curative effect is stable, has no toxic side effect and adverse reaction.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of Chinese medicine composition and its system for treating coronary disease and angina pectoris
Preparation Method.
Background technology
Coronary cardiopathy abbreviation coronary heart disease.Refer to because lipid-metabolism is abnormal, the lipid calmness in blood is in original
On this smooth endarterium, in endarterium, some accumulate similar to athero- lipid material forms white patch, referred to as artery
Atherosclerotic lesion.These patches increase gradually causes lumen of artery narrow, blood flow is obstructed, and causes heart ischemia, produces the heart and twists
Bitterly.
Coronary heart disease is due to that coronary atherosclerosis and coronary artery function sexually revise (spasm) and cause cardiac muscle temporary
Ictal pectoralgia caused by hypoxic-ischemic or the uncomfortable clinical syndrome mainly to show of chest.Coronary heart disease is also known as ischemic
Heart disease or coronary atherosclerotic heart disease.Belong to the card category such as traditional Chinese medical science chest impediment and cardialgia by its Symptoms.The obstruction of qi in the chest heart
Pain refers to pain uncomfortable in chest, very then chest pain radiating to the back, loses heart, a kind of disease that failing to sleep due to dyspnea is primary symptom, and the lighter only feels uncomfortable in chest and such as stopped up, exhales
Inhale and owe smooth, severe one then has pectoralgia, and severe patient chests pain radiating to the back, backache radiating to the heart.
At present, compared with the painful surgical intervention big, medical expense is high of operation and PCI, most of patients with coronary heart disease
It is more willing to select drug therapy.The medicine of existing treatment coronary heart disease is broadly divided into Western medicine and Chinese medicine.Western medicine mainly includes following
Several classes：(1) anti-platelet agent such as aspirin；(2) beta-blocker such as Betaloc；(3) Angiotensin-Converting presses down
Preparation such as battle pass；(4) blood lipid-lowering medicine；(5) nitrate esters medicine；(6) it is long-acting or sustained release dihydro arsenic pyridine class calcium antagonist and
Non- dihydro arsenic pyridine class calcium antagonist.Although these medicines can play a part of certain treatment and alleviation, therapeutic effect is limited,
Easily recurred after drug withdrawal, it is impossible to effect a radical cure coronary heart disease, and have certain toxic side effect.And the Chinese medicine of existing treatment coronary heart disease is former
Material is complicated, and expensive, although certain therapeutic effect can be obtained, curative effect is not sufficiently stable, and can not reach healing
Purpose.
The content of the invention
It is an object of the invention to：For above-mentioned problem, there is provided a kind of Chinese medicine group for treating coronary disease and angina pectoris
Compound and preparation method thereof, present composition compatibility is precise and appropriate, and raw material is simple and easy to get, have it is promoting blood circulation and removing blood stasis, remove obstruction in channels to relieve pain, QI invigorating
The effect of yin-nourishing, there is the effect of definite for coronary heart disease and angina pectoris.
In order to realize foregoing invention purpose, the technical solution adopted by the present invention is as follows：
A kind of Chinese medicine composition for treating coronary disease and angina pectoris, it is mainly original by Chinese medicine pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum
Material is made, and is according to parts by weight：Pseudo-ginseng 100-380 parts, red sage root 350-650 parts, American Ginseng 50-200 parts, ganoderma lucidum 5-80 parts.
It is preferred that a kind of Chinese medicine composition for treating coronary disease and angina pectoris, mainly by Chinese medicine pseudo-ginseng, the red sage root, American Ginseng and
Ganoderma lucidum is made up of raw material, is according to parts by weight：Pseudo-ginseng 200-300 parts, red sage root 450-550 parts, American Ginseng 100-150 parts, spirit
Sesame 35-65 parts.
It is preferred that a kind of Chinese medicine composition for treating coronary disease and angina pectoris, mainly by Chinese medicine pseudo-ginseng, the red sage root, American Ginseng and
Ganoderma lucidum is made up of raw material, is according to parts by weight：255 parts of pseudo-ginseng, 500 parts of the red sage root, 135 parts of American Ginseng, 50 parts of ganoderma lucidum.
Present invention also offers a kind of preparation method for the Chinese medicine composition for treating coronary disease and angina pectoris, by following steps group
Into：
(1) pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are proportionally weighed, pseudo-ginseng is crushed and wears into coarse powder, American Ginseng crushes
And fine powder is worn into, it is standby；
(2) red sage root, ganoderma lucidum and pseudo-ginseng coarse powder are put into pot for boiling chinese traditional medicine, and add and add water to cook 2-3 times, each 1-3h,
Collecting decoction, filtering, obtains filtrate；The weight of the water is 6-10 times of the red sage root, ganoderma lucidum and pseudo-ginseng gross weight；
(3) filtrate decompression is concentrated, obtains thick paste, the American Ginseng fine powder is added into thick paste, after being well mixed,
Capsule, tablet, granule, pill is made in preparation process according to routine.
It is preferred that present invention also offers a kind of preparation method for the Chinese medicine composition for treating coronary disease and angina pectoris, by with
Lower step composition：
(1) pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are proportionally weighed, pseudo-ginseng is crushed and wears into coarse powder, American Ginseng crushes
And fine powder is worn into, it is standby；
(2) red sage root, ganoderma lucidum and pseudo-ginseng coarse powder are put into pot for boiling chinese traditional medicine, and add and add water to cook 2 times, first time 1.5h,
Second of 1h, collecting decoction, filtering, obtain filtrate；The weight of the water is 8 times of the red sage root, ganoderma lucidum and pseudo-ginseng gross weight；
(3) filtrate decompression is concentrated, obtains thick paste, the American Ginseng fine powder is added into thick paste, after being well mixed,
Capsule, tablet, granule, pill is made in preparation process according to routine.
It is preferred that present invention also offers a kind of preparation method for the Chinese medicine composition for treating coronary disease and angina pectoris, by with
Lower step composition：
(1) pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are proportionally weighed, pseudo-ginseng is crushed and wears into coarse powder, American Ginseng crushes
And fine powder is worn into, it is standby；
(2) red sage root, ganoderma lucidum and pseudo-ginseng coarse powder are put into pot for boiling chinese traditional medicine, and add and add water to cook 2-3 times, each 1-3h,
Collecting decoction, filtering, obtains filtrate；The weight of the water is 6-10 times of the red sage root, ganoderma lucidum and pseudo-ginseng gross weight；
(3) filtrate decompression is concentrated, obtains thick paste, the American Ginseng fine powder is added into thick paste, and add starch
After well mixed, load capsule shells, be made 1000, produce the capsule.
It is preferred that in step (1), the particle diameter of the coarse powder is 600-700 μm, and the particle diameter of the fine powder is 100-150 μm.
It is preferred that in step (2), the film for being 50-80nm with aperture that is filtered into is filtered.
It is preferred that in step (3), relative density of the thick paste under the conditions of 60-80 DEG C is 1.15-1.25.
The compatibility of pharmaceutical composition of the present invention is according to being：Theory of traditional Chinese medical science thinks more than coronary heart disease and anginal generation and cold-evil
Inside invade, be improper diet, the factor such as disorder of emotion, aged debility it is relevant, its interpretation of the cause, onset and process of an illness has the aspect of the cold of insufficiency type two；Actually cold solidifying, the stagnation of the circulation of vital energy, blood
The stasis of blood, phlegm resistance, stagnated chest-YANG, stagnating heart meridian；Void is heart spleen caused by liver and kidney deficiency, functional disturbance.The stagnation of the heart blood be this sick common cause it
One, liver controlling conveyance and dispersion, store blood.Caused by disorder of emotion is often liver dysfunction, but extraneous direct stimulation, especially rude passion or mistake
The depression of degree, and usually make the catharsis malfunction of liver, and stagnation of liver qi, functional activity of QI being not smooth occur, and gas and blood, as shadow with
Shape, gas row then blood, the stagnation of the circulation of vital energy then blood stasis.Therefore stagnation of liver qi, gas not promoting circulation of blood, then thrombosis, influence the function of blood stored in the liver, so that it may
It is uncomfortable in chest to there is pectoralgia, fullness in chest and hypochondrium.And the obstruction of qi in the chest with the passing of time impairment of yin, the deficiency of Yin cause train of thought unfavorable again, hematogenous blockage, hemostasis obstruction, heart mistake
Support, then cause palpitation and uneasiness, purplish tongue, deep and hesitant pulse is then the time of the stagnation of the heart blood.This disease both be the stagnation of the heart blood caused by, when with
It is promoting blood circulation and removing blood stasis, remove obstruction in channels to relieve pain as method.
In combination of the above thing：
Pseudo-ginseng nature and flavor are sweet, slight bitter, temperature, Return liver, stomach, have the effect of removing blood stasis and hemostasis, promoting blood circulation analgesic therapy, are monarch drug in a prescription.
The red sage root is bitter in taste, is slightly cold, the thoughts of returning home, pericardium, Liver Channel, and can pass through blood vessels, aids in monarch drug in a prescription pseudo-ginseng blood-circulation-invigovating dissolving stasis, and dredging collateral stops
Bitterly, it is ministerial drug.
American Ginseng is bitter in taste, micro-sweet, trembles with fear, the thoughts of returning home, lung, kidney channel, energy boosting qi and nourishing yin, relieves inflammation or internal heat and promotes the production of body fluid；Ganoderma lucidum property sweet taste, returns
The heart, lung, liver and kidney channel, there is the effect of invigorating qi for tranquilization, relieving cough and asthma.With the passing of time, deficiency of both qi and yin, the deficiency of vital energy is then difficult promoting circulation of blood, the deficiency of Yin to bi Zheng
Then train of thought is unfavorable, and the deficiency of vital energy can make hematogenous blockage, stagnation of QI-blood with the deficiency of Yin, therefore we are helped with American Ginseng and ganoderma lucidum again.
Above all medicines share, altogether into coronary circulation-promoting pain-relieving, the agent of supplementing qi and nourishing yin, for heart arteries and veins stasis blocking and the type of deficiency of both QI and YIN obstruction of qi in the chest heart
Bitterly, i.e., modern medicine is referred to as coronary disease and angina pectoris.
In summary, by adopting the above-described technical solution, the beneficial effects of the invention are as follows：
The present invention is according to the dialectical theory of the traditional Chinese medical science, complete square reasonable compatibility, using pseudo-ginseng as monarch drug in a prescription；Using the red sage root as ministerial drug, to the west of
American ginseng, ganoderma lucidum are adjutant, from chest qi, it is promoting blood circulation and removing blood stasis, remove obstruction in channels to relieve pain and start with, while emphasize nourishing Yin and clearing heat, diuresis defaecation, will
Human body carries out overall dialectical conditioning and treatment, so as to reach the purpose for thoroughly curing coronary heart diseases and angina pectoris.The Chinese medicine of the present invention
Composition material is simple and easy to get, cheap, curative effect is stable, has no toxic side effect and adverse reaction.
Embodiment
For the objects, technical solutions and advantages of the present invention are more clearly understood, preferred embodiment is enumerated below, to this hair
Bright further description.However, it is necessary to illustrate, many details listed in specification are used for the purpose of making reader to this
The one or more aspects of invention have a thorough explanation, can also realize the present invention's even without these specific details
These aspects.
Embodiment 1
A kind of Chinese medicine composition for treating coronary disease and angina pectoris, it is mainly original by Chinese medicine pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum
Material is made, and is according to parts by weight：Pseudo-ginseng 255g, red sage root 500g, American Ginseng 135g, ganoderma lucidum 50g.
Present invention also offers a kind of preparation method for the Chinese medicine composition for treating coronary disease and angina pectoris, by following steps group
Into：
(1) pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are proportionally weighed, it is 600 μm thick to crush and wear into particle diameter pseudo-ginseng
Powder, American Ginseng crushes and wears into the fine powder that particle diameter is 150 μm, standby；
(2) red sage root, ganoderma lucidum and pseudo-ginseng coarse powder are put into pot for boiling chinese traditional medicine, and add and add water to cook 2 times, each 3h, merged
Decocting liquid, the film for being 50nm with aperture are filtered, and obtain filtrate；The weight of the water is the 6 of the red sage root, ganoderma lucidum and pseudo-ginseng gross weight
Times；
(3) filtrate decompression is concentrated, the thick paste that the relative density under the conditions of 60 DEG C is 1.15 is obtained, into thick paste
The American Ginseng fine powder is added, after being well mixed, is dried with HighefficientFluidbeddrier, controls 90 DEG C of EAT, dries air-out
Temperature is 50 DEG C, and it is 7% to dry to moisture；Whole grain is sieved with multi-functional pelletizing machine 5.0mm, produces granule.
Embodiment 2
A kind of Chinese medicine composition for treating coronary disease and angina pectoris, it is mainly original by Chinese medicine pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum
Material is made, and is according to parts by weight：Pseudo-ginseng 100g, red sage root 350g, American Ginseng 50g, ganoderma lucidum 5g.
Present invention also offers a kind of preparation method for the Chinese medicine composition for treating coronary disease and angina pectoris, by following steps group
Into：
(1) pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are proportionally weighed, it is 600 μm thick to crush and wear into particle diameter pseudo-ginseng
Powder, American Ginseng crushes and wears into the fine powder that particle diameter is 150 μm, standby；
(2) red sage root, ganoderma lucidum and pseudo-ginseng coarse powder are put into pot for boiling chinese traditional medicine, and add and add water to cook 2 times, each 3h, merged
Decocting liquid, the film for being 80nm with aperture are filtered, and obtain filtrate；The weight of the water is the red sage root, ganoderma lucidum and pseudo-ginseng gross weight
10 times；
(3) filtrate decompression is concentrated, the thick paste that the relative density under the conditions of 80 DEG C is 1.25 is obtained, into thick paste
The American Ginseng fine powder is added, after being well mixed, is dried with HighefficientFluidbeddrier, controls 95 DEG C of EAT, dries air-out
Temperature is 55 DEG C, and it is 5% to dry to moisture；Whole grain is sieved with multi-functional pelletizing machine 2.0mm, adds peppermint oil dementholized and magnesium stearate,
Mix, tabletting, the pre-heat treatment 85 DEG C of preheating 1h i.e. in hot air circulation drying oven are carried out to plain piece, coating, obtain tablet.
Embodiment 3
A kind of Chinese medicine composition for treating coronary disease and angina pectoris, it is mainly original by Chinese medicine pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum
Material is made, and is according to parts by weight：Pseudo-ginseng 380g, red sage root 650g, American Ginseng 200g, ganoderma lucidum 80g.
Present invention also offers a kind of preparation method for the Chinese medicine composition for treating coronary disease and angina pectoris, by following steps group
Into：
(1) pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are proportionally weighed, it is 600 μm thick to crush and wear into particle diameter pseudo-ginseng
Powder, American Ginseng crushes and wears into the fine powder that particle diameter is 150 μm, standby；
(2) red sage root, ganoderma lucidum and pseudo-ginseng coarse powder are put into pot for boiling chinese traditional medicine, and add and add water to cook 2 times, first time 1.5h,
Second of 1h, collecting decoction, the film for being 60nm with aperture are filtered, and obtain filtrate；The weight of the water be the red sage root, ganoderma lucidum and
8 times of pseudo-ginseng gross weight；
(3) filtrate decompression is concentrated, the thick paste that the relative density under the conditions of 60 DEG C is 1.15 is obtained, into thick paste
The American Ginseng fine powder is added, after being well mixed, is dried with HighefficientFluidbeddrier, controls 95 DEG C of EAT, dries air-out
Temperature is 55 DEG C, and it is 5% to dry to moisture；Whole grain is sieved with multi-functional pelletizing machine 2.0mm, adds peppermint oil dementholized and magnesium stearate,
Mix, tabletting, the pre-heat treatment 85 DEG C of preheating 1h i.e. in hot air circulation drying oven are carried out to plain piece, coating, obtain tablet.
Embodiment 4
A kind of Chinese medicine composition for treating coronary disease and angina pectoris, it is mainly original by Chinese medicine pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum
Material is made, and is according to parts by weight：Pseudo-ginseng 200g, red sage root 450g, American Ginseng 100g, ganoderma lucidum 35g.
Present invention also offers a kind of preparation method for the Chinese medicine composition for treating coronary disease and angina pectoris, by following steps group
Into：
(1) pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are proportionally weighed, it is 700 μm thick to crush and wear into particle diameter pseudo-ginseng
Powder, American Ginseng crushes and wears into the fine powder that particle diameter is 100 μm, standby；
(2) red sage root, ganoderma lucidum and pseudo-ginseng coarse powder are put into pot for boiling chinese traditional medicine, and add and add water to cook 2 times, first time 1.5h,
Second of 1h, collecting decoction, the film for being 60nm with aperture are filtered, and obtain filtrate；The weight of the water be the red sage root, ganoderma lucidum and
8 times of pseudo-ginseng gross weight；
(3) filtrate decompression is concentrated, the thick paste that the relative density under the conditions of 60 DEG C is 1.15 is obtained, into thick paste
Add the American Ginseng fine powder, and add starch it is well mixed after, load capsule shells, be made 1000, produce the capsule.
Embodiment 5
A kind of Chinese medicine composition for treating coronary disease and angina pectoris, it is mainly original by Chinese medicine pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum
Material is made, and is according to parts by weight：Pseudo-ginseng 300g, red sage root 550g, American Ginseng 150g, ganoderma lucidum 65g.
Present invention also offers a kind of preparation method for the Chinese medicine composition for treating coronary disease and angina pectoris, by following steps group
Into：
(1) pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are proportionally weighed, it is 700 μm thick to crush and wear into particle diameter pseudo-ginseng
Powder, American Ginseng crushes and wears into the fine powder that particle diameter is 100 μm, standby；
(2) red sage root, ganoderma lucidum and pseudo-ginseng coarse powder are put into pot for boiling chinese traditional medicine, and add and add water to cook 3 times, each 1h, merged
Decocting liquid, the film for being 60nm with aperture are filtered, and obtain filtrate；The weight of the water is the 8 of the red sage root, ganoderma lucidum and pseudo-ginseng gross weight
Times；
(3) filtrate decompression is concentrated, the thick paste that the relative density under the conditions of 60 DEG C is 1.15 is obtained, into thick paste
The American Ginseng fine powder is added, after being well mixed, pill is made according to the preparation process of routine.
The application method of Chinese medicine composition of present invention treatment coronary disease and angina pectoris is：General capsule is 3 tablets each time, often
Day is twice；Tablet, granule, pill are each 3-5 grains, and twice daily, 2 weeks are a course for the treatment of.It is cold, pungent that raw meat is avoided during medication
Food.It is not taken by pregnant women, patients with heart failure uses with caution.
Clinical observation on the therapeutic effect：
1. case：80 Treating Patients of Angina Pectoris are randomly divided into two groups --- treatment group and control group.Treatment group 40
Example, man 25, female 15, age 42-70 year, average age 61 years old, course of disease 1-13, average course of disease 7.5 years；Control group 40
Example, man 23, female 17, age 41-69 year, average age 61.8 years old, course of disease 1-12, average course of disease 7.1 years.All patients
Before the treatment, surgical intervention and PCI are not received.All condition-inferences accept and believe the diagnosis that regular hospital provides；
And 2 groups of cases are statistically analyzed without significant difference (P in sex, age, protopathy, disease time, the state of an illness etc.>
0.05), there is comparativity.
2. treatment method：Treatment group patient takes the capsule of the treatment coronary disease and angina pectoris of the embodiment of the present invention 4, control
Group patient takes conventional medicine sorbitrate tablet.2 months are 1 course for the treatment of, and two groups are treated 2 courses for the treatment of.
3. ECG curative effect criterion：
It is effective：Electrocardiogram recovers to " substantially normal " (i.e. " normal range (NR) ") or reached " normal ECG "；
Effectively：The reduction of S-T segment, with more than rise 0.05mv after treatment, but not up to normal level；Fallen in main lead
Put that T ripples shoal and (reach more than 25% person) or T ripples are changed into upright from flat, chamber or intraventricular block improver；
It is invalid：Electrocardiogram is substantially identical with before treatment；
Aggravate：S-T segment reduces more than 0.05mv before relatively treating, and deepens (to reach more than 25% in main lead negative T wave
Person) or uprightly T ripples become flat, flat T ripples, which become, to be inverted, and ectopic cardiac rhythm, atrioventricular block or intraventricular block occurs.
4. treatment results：
Table 1 is the treatment results for the treatment of group and control group.
Table 1
| Medication | Number of cases | It is effective | Effectively | It is invalid | Aggravate | Total effective rate |
| Treatment group | 40 | 29 | 10 | 1 | 0 | 97.5% |
| Control group | 40 | 21 | 12 | 6 | 1 | 82.5% |
As it can be seen from table 1 effective 29 for the treatment of group, obvious effective rate 72.5%, total effective rate 98.3%；Control group shows
Effect 21, obvious effective rate 52.5%, total effective rate 82.5%.The effect for the treatment of group, is better than control group, and treatment group is rear equal
Without recurrence.
In addition, Chinese medicine composition of the present invention has no toxic side effect, through acute toxicity test and long term toxicity test, press
The dose that clinic allows gives mouse stomach, and mouse activity is normal；It is administered by the Cmax that clinic allows to rat, rat lives
Dynamic and every testing result is without exception.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (9)
- A kind of 1. Chinese medicine composition for treating coronary disease and angina pectoris, it is characterised in that：Mainly by Chinese medicine pseudo-ginseng, the red sage root, American Ginseng And ganoderma lucidum is made up of raw material, it is according to parts by weight：Pseudo-ginseng 100-380 parts, red sage root 350-650 parts, American Ginseng 50-200 parts, spirit Sesame 5-80 parts.
- A kind of 2. Chinese medicine composition for treating coronary disease and angina pectoris according to claim 1, it is characterised in that：Mainly in Medicine pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are made up of raw material, are according to parts by weight：Pseudo-ginseng 200-300 parts, red sage root 450-550 Part, American Ginseng 100-150 parts, ganoderma lucidum 35-65 parts.
- A kind of 3. Chinese medicine composition for treating coronary disease and angina pectoris according to claim 1, it is characterised in that：Mainly in Medicine pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are made up of raw material, are according to parts by weight：255 parts of pseudo-ginseng, 500 parts of the red sage root, American Ginseng 135 parts, 50 parts of ganoderma lucidum.
- 4. a kind of preparation method of Chinese medicine composition for treating coronary disease and angina pectoris according to any one of claims 1 to 3, It is characterized in that：Comprise the steps of：(1) pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are proportionally weighed, pseudo-ginseng is crushed and wears into coarse powder, American Ginseng is crushed and ground It is standby into fine powder；(2) red sage root, ganoderma lucidum and pseudo-ginseng coarse powder are put into pot for boiling chinese traditional medicine, and add and add water to cook 2-3 times, each 1-3h, merged Decocting liquid, filtering, obtains filtrate；The weight of the water is 6-10 times of the red sage root, ganoderma lucidum and pseudo-ginseng gross weight；(3) filtrate decompression is concentrated, obtains thick paste, the American Ginseng fine powder is added into thick paste, after being well mixed, according to Capsule, tablet, granule, pill is made in conventional preparation process.
- 5. a kind of preparation method of Chinese medicine composition for treating coronary disease and angina pectoris according to claim 4, its feature exist In：Comprise the steps of：(1) pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are proportionally weighed, pseudo-ginseng is crushed and wears into coarse powder, American Ginseng is crushed and ground It is standby into fine powder；(2) red sage root, ganoderma lucidum and pseudo-ginseng coarse powder are put into pot for boiling chinese traditional medicine, and add and add water to cook 2 times, first time 1.5h, second Secondary 1h, collecting decoction, filtering, obtain filtrate；The weight of the water is 8 times of the red sage root, ganoderma lucidum and pseudo-ginseng gross weight；(3) filtrate decompression is concentrated, obtains thick paste, the American Ginseng fine powder is added into thick paste, after being well mixed, according to Capsule, tablet, granule, pill is made in conventional preparation process.
- 6. a kind of preparation method of Chinese medicine composition for treating coronary disease and angina pectoris according to claim 4, its feature exist In：Comprise the steps of：(1) pseudo-ginseng, the red sage root, American Ginseng and ganoderma lucidum are proportionally weighed, pseudo-ginseng is crushed and wears into coarse powder, American Ginseng is crushed and ground It is standby into fine powder；(2) red sage root, ganoderma lucidum and pseudo-ginseng coarse powder are put into pot for boiling chinese traditional medicine, and add and add water to cook 2-3 times, each 1-3h, merged Decocting liquid, filtering, obtains filtrate；The weight of the water is 6-10 times of the red sage root, ganoderma lucidum and pseudo-ginseng gross weight；(3) filtrate decompression is concentrated, obtains thick paste, the American Ginseng fine powder is added into thick paste, and add starch mixing After uniformly, load capsule shells, be made 1000, produce the capsule.
- 7. a kind of preparation method of Chinese medicine composition for treating coronary disease and angina pectoris according to claim 4, its feature exist In：In step (1), the particle diameter of the coarse powder is 600-700 μm, and the particle diameter of the fine powder is 100-150 μm.
- 8. a kind of preparation method of Chinese medicine composition for treating coronary disease and angina pectoris according to claim 4, its feature exist In：In step (2), the film for being 50-80nm with aperture that is filtered into is filtered.
- 9. a kind of preparation method of Chinese medicine composition for treating coronary disease and angina pectoris according to claim 4, its feature exist In：In step (3), relative density of the thick paste under the conditions of 60-80 DEG C is 1.15-1.25.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108686096A (en) * | 2018-08-17 | 2018-10-23 | 陶秀英 | A kind of Chinese patent drug and preparation method thereof for treating coronary heart disease |
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| CN101284046A (en) * | 2008-05-26 | 2008-10-15 | 北京市科威华食品工程技术有限公司 | Thrombus clear health soft capsules |
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| CN108686096A (en) * | 2018-08-17 | 2018-10-23 | 陶秀英 | A kind of Chinese patent drug and preparation method thereof for treating coronary heart disease |
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Application publication date: 20171212 |