CN107441329A - A kind of Chinese medicinal formulae nursed one's health for diabetes and Sjogren syndrome - Google Patents
A kind of Chinese medicinal formulae nursed one's health for diabetes and Sjogren syndrome Download PDFInfo
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- CN107441329A CN107441329A CN201610367493.1A CN201610367493A CN107441329A CN 107441329 A CN107441329 A CN 107441329A CN 201610367493 A CN201610367493 A CN 201610367493A CN 107441329 A CN107441329 A CN 107441329A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
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Abstract
The present invention relates to a kind of Chinese medicinal formulae nursed one's health for diabetes and Sjogren syndrome.Its prescription is made up of the Chinese medicine of following parts by weight：Chinese yam, mulberry fruit, lily, radix polygonati officinalis, dark plum, raw hawthorn, the root of kudzu vine, Buddha's hand.This Chinese medicine passes through scientific composition, and Clinical practice checking curative effect through experimental study and for many years.It has the effect of fine to diabetes and Sjogren syndrome, can effectively improve diabetes and the clinical symptoms of Sjogren syndrome.
Description
Technical field
The present invention relates to the field of Chinese medicines, for a kind of Chinese medicinal formulae nursed one's health for diabetes and Sjogren syndrome.
Background technology
Diabetes are a kind of common incretion metabolism diseases.Its state of an illness physiological change be due to insulin definitely or relative deficiency,
Cause sugar, fat, protein and Secondary cases vitamin, water and electrolyte metabolism disorderly.It is characterized in that blood glucose is too high, glycosuria,
Grape impaired glucose tolerance, and insulin release test are abnormal.The incidence of disease of diabetes increases with the age, peak 60 years old with
On, it is common complaint among the elderly and frequently-occurring disease.Diabetes are divided into insulin-dependent (I types) and non-insulin-depending type (II
Type), senile diabetes are in the majority with II type persons.This disease belong to motherland's medical science quench one's thirst, disappear illness scope.With the development of society, the mankind
The change of diet work and rest, diabetes have turned into the social public health problem of many national extensive concerns.
The treatment of diabetes include diabetes education, dietary therapy, exercise therapy, drug therapy, blood sugar monitoring and other
The detection of the cardiovascular disease risk factor and the several aspects of control.
For type ii diabetes, due to itself being the relative hyposecretion of insulin, for a long time using Drugs Promoting Insulin Secretion or pancreas islet
Once quick dose of element, can produce a desired effect in short term.But the mechanism that insulin relative deficiency occurs for body does not become, therefore, body meeting
Each organ function is gradually adjusted, causes the reaction of insulin level or several days cells to insulin, and slowly returns to original level,
Here it is so-called drug resistance.
Traditional Chinese medicine integrally considers that prescription sends medicine from body, infringement and its function to slowing down eye, kidney, angiocarpy and nervous system
Obstacle and exhaustion, it is very helpful, and also toxic side effect is smaller.
Sjogren syndrome is a kind of not clear autoimmunity for involving the eccrine pipeline epithelial cell chronic inflammation of whole body of reason
Property CTD, it is main to invade lachrymal gland and salivary gland, using mouth xerophthalmia scheorma and occur together CTD as Clinical symptoms.This disease is sent out
Sick rate is higher, can betide any age, but 40 years old is more with sequela person, and women patient is common, and due to controlling without special efficacy
Treatment method, turn into the emphasis research topic in gerontology.
Sjogren syndrome is a kind of autoimmune connective tissue disease, and pathogenic factor is unclear, thus it is speculated that relevant with following factor：
1. inherent cause.Primary Sjogren's syndrome has the report that family falls ill, therefore speculates that this disease is relevant with inherent cause.
2. virus infection.The I g M type antibody titers for detecting serum anti-cytomegalovirus in the blood of this patient increase, therefore recognize
It is relevant with viral infection for the morbidity of this disease, there is evidence that Epstein-Barr virus works in the morbidity that this disease merges rheumatoid arthritis.
Sjogren syndrome onset is relatively hidden, and is made slow progress, and only small number of patients morbidity is anxious, and progress is fast.Due to it, to involve whole body more
System, therefore often performance is complicated, only sees mouth, xerophthalmia scheorma person, is primary Sjogren's syndrome, also known as mouth xerophthalmia scheorma syndrome, closes
And have other connective tissue disease persons, claim secondary Sjogren syndrome.Specific clinical manifestation is visible：
1. xerostomia.Disease the lighter is not easy to discover, and disease severe one is shown in that saliva is reduced, and food and chewing are unable to exciting salivary secretion,
Tongue is red and dry, or has ulcer, the dysphagia because of dry throat, is often accompanied by gingival inflammation, and tooth is broken to drop, dry lip shattered crack,
Or have halitosis, half patient's parotid gland enlargement recurrent exerbation, even it is in squirrel sample face, salivary gland also normal enlargement.
2. xerophthalmia scheorma.Showing as keratoconjunctivitis sicca, eyes are dry, pain of itching, and have foreign body sensation, a burn feeling, eye-blurred,
Seemingly there is curtain, keep in dark place, the heavy then opacity of the cornea, there is rotten to the corn or ulcer, even perforation.Because tear is reduced, normal concurrent bacterial,
Virus or fungal infection.
3. respiratory tract is dried.Show as mycteroxerosis, conduction deafness, dry throat, hoarseness, thick sputum, easily simultaneously
Gas producing tube, bronchus, the inflammation of lung.
The current doctor trained in Western medicine of Sjogren syndrome does not have special treatment method, commonly uses liquid preparation for external application, improves local desiccation symptom, has
When serious function changes or has an impact the complication of life, adrenocortical hormones in treating can be used, such as prednisone 10 milli every time
Gram, 3 times a day, gradually it is reduced after symptom improvement, and be discontinued as early as possible；With symptom outside body of gland, CAH,
During pseudolymphoma etc., immunodepressant, such as endoxan, daily 2~4 milligrams of per kilogram of body weight, or imuran can be used,
Daily 2~3 milligrams of per kilogram of body weight；Antibiotic should be timely used during accompanying infection.
Sjogren syndrome belongs to " dry card " category of the traditional Chinese medical science, and the scorching poison of diseases caused by external factors is evil, froms superficies to interior, and damage lung Tianjin, consumes gastric juice,
Liver-kidney Yin deficiency is caused eventually；The deficiency of liver-yin and kidney-yin, consumption of body fluid due to lung-dryness, show as mouth, xeromycteria, two xerophtalmias, the few phlegm of dry cough；Or blood stasis network
Resistance, shows as dry skin such as fish scale, even there is hepatosplenomegaly.Or feelings will is unsuccessful, it is strongly fragrant and change fire, intimately hinder Tianjin；Or ferritic
The deficiency of liver-yin and kidney-yin, it is added with sweat, tells, lower rear body fluid injures and deaths, cause Tianjin blood trouble to lose eventually, dry card is into.
Diabetes adhere to different diseases, but the interpretation of the cause, onset and process of an illness of the two from traditional Chinese medical science angle separately from Sjogren syndrome in modern diseases classification
There is syndrome of deficiency of both qi and yin, therefore clinically often find that many diabetics have Sjogren syndrome concurrently.From constitution theory in traditional Chinese medicine
From the point of view of constitution correlation theory, both diseases belong to the disease occurred frequently of yin-deficiency constitution crowd.In treatment, deficiency of both qi and yin is exaggerated, such as
Fruit using extremely cold product, such as dried rhizome of rehmannia, radix scrophulariae, balsam pear, root of Chinese trichosanthes, the coptis, golden cypress, radix scutellariae, can aggravate disappearing for gas rashly
Consumption, and aggravate deficiency of both qi and yin symptom.And the anxiety of the product, again having burn the moon of long-term use of high benefit, all it is unfavorable for deficiency of both qi and yin trouble
Person is long-term use of.Treatment of both diseases in reality is both needed to long-time conditioning medication, as the two get both more needed can QI invigorating support
The moon, and without there is high mend to grow the prescriptions of the product that greasy, bitter cold is exaggerated to carry out long-time conditioning.The prescription of this invention is controlled to be specially directed to
Treat the prescription of diabetes and Sjogren syndrome, portion of main inventive people's behaviour society, the Academic Degrees Committee of the State Council, the Ministry of Education, the Ministry of Public Health,
National old docter of TCM's medicine expert that 5 big ministries and commissions of State Administration of Traditional Chinese Medicine joint is assert, took up a job as a doctor for more than 50 years.For many years based on this side
Diabetes and the hundreds of examples of Sjogren syndrome are clinically treated in plus-minus change, obtain the effect of fine.The claims in the present invention are led
The medicinal material content range opened becomes for specifically for the recipe quantity designed in patent medicine and food development, its prescription medicinal material usage amount is formed
For change situation from not publicly leaking, all very refining is reasonable for the prescription and dosage of prescription of the present invention, safe to use, is particularly suitable for
Develop into the Chinese patent drug and food for the treatment of diabetes and Sjogren syndrome.
The content of the invention
This invention provides a kind of Chinese medicinal formulae nursed one's health for diabetes and Sjogren syndrome, is that inventor controls through clinic for many years
The summary of diabetes experience, for the treatment of diabetes and Sjogren syndrome, start with from conditioning yin-deficiency constitution, and make a special trip to a certain place and be directed to
The mouthfeel of yin-deficiency constitution crowd carries out prescription screening design to strengthen the compliance that patient takes.It is provided by the present invention to be used for glycosuria
The Chinese medicinal formulae of sick and Sjogren syndrome conditioning is curative for effect, refining formula safety, is adapted to long-term use, it is new to be particularly suitable for Chinese medicine
Medicine and food industries exploitation.
The technical solution adopted by the present invention is：
A kind of Chinese medicinal formulae nursed one's health for diabetes and Sjogren syndrome, it is characterized in that being made up of the Chinese medicine of following parts by weight：
5~20 parts of Chinese yam, 5~20 parts of mulberry fruit, 10~30 parts of lily, 5~20 parts of radix polygonati officinalis, 5~20 parts of dark plum, raw hawthorn 10~
30 parts, 10~30 parts of the root of kudzu vine, 5~20 parts of Buddha's hand.
As preference：
The Chinese medicine material parts by weight form as follows：6~15 parts of Chinese yam, 6~15 parts of mulberry fruit, 12~20 parts of lily, radix polygonati officinalis 6~15
Part, 6~15 parts of dark plum, 12~20 parts of raw hawthorn, 12~20 parts of the root of kudzu vine, 6~15 parts of Buddha's hand.
Further preferably institute's Chinese medicine material parts by weight are configured to：12 parts of Chinese yam, 10 parts of mulberry fruit, 15 parts of lily, 12 parts of radix polygonati officinalis, crow
10 parts of plum, 15 parts of raw hawthorn, 15 parts of the root of kudzu vine, 10 parts of Buddha's hand.
The major function of Chinese medicinal formulae of the present invention is：Supplementing qi and nourishing yin, promote the production of body fluid to quench thirst, it is promoting blood circulation and removing blood stasis.Suitable for deficiency of both qi and yin
The type ii diabetes of blood stasis and Sjogren syndrome crowd.Demonstrate,prove and see because of deficiency of both qi and yin, thirsty more drinks caused by blood-stasis internal-depression or Tianjin slightly liquid wound,
Lip and tongue dryness, the puckery few tear of mesh, body are become thin, and dizzy, blurred vision, dry skin, itch or eye are done, and stool is dry,
Yellow urine, the red few tongue of tongue, thready rapid pulse or mouth are dry, drinking the water in the mouth but no desire to swallow, and complexion is dark or dark red, cyanosis of the lips and nails, tongue nature purple is dim,
Petechia, ecchymosis, livid purple under glossodemus, uneven pulse or knot generation etc..Its prescription side's solution is that the mechanism of action is：
The basic pathogenesis deficiency of both qi and yin of type ii diabetes.Because diabetes delay with the passing of time refractory, " pathogen usually intruding into collateral in protracted disease ", " prolonged illness into the stasis of blood ",
Yin jin virtual loss, blood vessels do not fill, and blood is unfavorable, not smooth not smooth, cause stagnation of blood stasis, so as to cause diabetic microvascular complication such as
Microcirculation disorder, microaneurysm are formed and microvascular basement membrane thickens, and causes multi viscera lesion, is that diabetes are most common and serious
One of chronic complicating diseases.Sjogren syndrome is deficiency of both qi and yin, or blood stasis resistance network.Therefore, supplementing qi and nourishing yin, promote the production of body fluid to quench thirst, invigorate blood circulation
Stagnation resolvation is traditional Chinese medical science conditioning diabetes, the basic principle of Sjogren syndrome, especially diabetic microvascular complication.
Chinese yam return lung, spleen, kidney channel in side, the gas of energy help spleen and lung, and the puckery essence of kidney tonifying that can promote the production of body fluid,《Book on Chinese herbal medicine is through reading》Described in mountain
Medicine energy kidney tonifying, essence replenishing, then cloudy strong, ear acute hearing, mesh are bright for essence foot, and modern pharmacological research shows, Chinese yam contains mucus protein, there is reduction
The effect of blood glucose；Mulberry fruit is nourishing liver and kidney, and energy nourishing yin and nourishing blood promotes the production of body fluid, and modern pharmacological research shows, the mulberry polysaccharide tool in mulberry fruit
Play the role of significantly to reduce blood glucose in diabetic rats and HbAlc contents, increase insulin sensitivity, regulating lipid metabolism；Two
Medicine reinforcing both QI and YIN, set for " deficiency of both qi and yin " basic pathogenesis, be monarch drug in a prescription.Radix polygonati officinalis nourishing yin to moisten dryness, promotes the production of body fluid to quench thirst, modern pharmacology
Research shows that it, which extracts flavonoid substances, has the effect such as hypoglycemic, blood fat, blood pressure；Lily is sweet, slight bitter, is slightly cold, and can support
Cloudy moistening lung, clearing away the heart fire and tranquillizing, with relieving restlessness；It is hawthorn spleen benefiting and stimulating the appetite, relieving dyspepsia, promoting blood circulation and removing blood stasis, can expand blood vessel, reduce blood glucose,
Reduce blood pressure；The root of kudzu vine, rise Tianjin and quench the thirst, modern pharmacological research shows, the root of kudzu vine is known as the effect of obvious reduction blood glucose, and can expand
Blood vessel is opened, diabetic microvascular complication can be improved；Four medicines distinguish Yin-nourishing and body fluid promoting, promoting blood circulation and removing blood stasis, expansion and softening blood vessel, altogether
For ministerial drug.Dark plum, promote the production of body fluid to quench thirst, the yellow female load of Qing Dynasty doctor《The four sages study quench one's thirst root original》：" person of quenching one's thirst faints the disease of the moon enough
...." dark plum enters cloudy Liver Channel of fainting, can nourishing the liver and kidney the moon, its ingredient plum acid can soften blood vessel, postpone vascular sclerosis,
Make with anti-senility；Buddha's hand is pungent, bitter, sweet, warm, dispersing stagnated hepatoqi, and compatibility group drugs for nourishing yin does not hinder gas with enriching yin, it is sweet and
Profit, the disadvantage of impairment of yin without dry；Two medicines promote the production of body fluid to quench thirst, vital energy regualting and blood circulation-promoting, are all adjutant.The product of the high benefits of Fang Zhongwu, unexpected residual air
Burn is cloudy；Product in side also without pungent-warm promoting the circulation of qi, therefore without the anxiety of pungent-warm gas consumption impairment of yin.All medicines share, supplementing qi and nourishing yin is played altogether, promote the production of body fluid
Quench the thirst, work(promoting blood circulation and removing blood stasis.And it is long-term use of containing hawthorn, Buddha's hand, spleen benefiting and stimulating the appetite, liver-smoothing, qi-regulating, and do not hinder stomach and hinder spleen
With the suspicion of impaction.
The pharmacological action of each compatibility Chinese medicine is described below in prescription：
Chinese yam：For Dioscoreaceae plant Chinese yam Dioscorea opposita Thunb. or congener dioscorea japonica Dioscorea japonica
Thunb. dry rhizome.Return lung, spleen, kidney channel, it is sweet mild-natured；With tonifying spleen nourishing the stomach, engender liquid and benefic lung, the work(of the puckery essence of kidney tonifying.
For spleen eating less, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, and under band, frequent micturition, abnormal heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) tonifying spleen is good for
Stomach.For spleen eating less, diarrhea loose stool, leukorrhea.Chinese yam stem tuber and root contain diosgenin, dopamine, cholesterine,
A variety of sterols such as ergosterol, campesterol, stigmasterol, cupreol, polyphenol oxidase, allantoin, only power is plain, sugared egg
Bletilla lysine, histidine, arginine, aspartic acid, threonine, serine, glutamic acid, proline, glycine, third
The amino acid such as propylhomoserin, valine, leucine, isoleucine, cruel propylhomoserin, phenylalanine and methionine, it is another hypoglycemic containing having
Make useful polysaccharide, various trace elements.Modern pharmacology proves to have hypoglycemic, anti allergic reaction, improves the effect such as immunity of organisms.
Mulberry fruit：For moraceae plants mulberry Morus alba L. drying fruit ear.Sweet acid is cold in nature, the thoughts of returning home, liver and kidney channel；Function is enriched blood taste
The moon, fluid dryness.Containing sugar, malic acid, malic acid and vitamin B1, B2, C and carrotene and flavones etc..For dizziness
Tinnitus, palpitation and insomnia, poliosis, injury thirst, Heat Diabetes, blood deficiency and constipation.
Lily：For liliaceous plant tiger lily Lilium lancifolium Thunb., lily Lilium brownii F.E.Brown var.
Viridulum Baker or Lilium tenuifolium Lilium pumilum DC. and its dry meat scale leaf for belonging to various plants bulb together.It is sweet
It is cold in nature.Enter the heart, lung channel.With moisten the lung and relieve the cough, clearing away the heart fire and tranquillizing the effect of.Clinic cure mainly tuberculosis cough long, cough saliva phlegm blood, pyreticosis
Waste heat unclear, dysphoria palpitates with fear, wandering, beriberi edema etc. afterwards.Modern study main component has a variety of biologies such as colchicin
Alkali and starch, protein, fat, cardiolipin and phosphorus aliphatic acid etc..Pharmacology confirm with cough-relieving, eliminating the phlegm, relieving asthma,
Raise peripheral leukocytes and anti-allergic effects.
Radix polygonati officinalis：For liliaceous plant radix polygonati officinalis Polygonatum odoratum (Mill.) Druce dry rhizome.It is sweet to be slightly cold,
Tortoise lung, stomach.With nourishing yin to moisten dryness, the work(to promote the production of body fluid to quench thirst.Hinder for lung stomach-Yin, cough caused by dryness-heat, dry throat and mouth, interior heat disappears
Yearningly.The polysaccharides such as mucopolysaccharide containing radix polygonati officinalis, radix polygonati officinalis levulan, sealwort spiral shell sterol, sealwort spiral shell sterol glycoside, sealwort furan sterol glycoside, Huang
The steroids such as smart furan sterol glycoside.Experiment shows that radix polygonati officinalis decoction has slow boosting to anesthetized rabbit, separately has been reported that radix polygonati officinalis decoction
There is of short duration antihypertensive effect to anesthetized dog, rabbit.Radix polygonati officinalis glycocide and its preparation have cardiotonic to isolated frog heart.Radix polygonati officinalis parenteral solution
0.2ml/kg is injected intravenously in rabbit, to cardiac contractile force in place and heart rate without obvious effect.It is anxious to the rabbit caused by pituitrin
Property myocardial ischemia has certain protective role.Isolated rabbit ear vessls, which are tested, to be shown, 100% radix polygonati officinalis parenteral solution 0.4ml/kg, by defeated
Inject, distend the blood vessels in liquid pipe.And retain the isolated rabbit ear blood vessel that links of nerve, by injecting 0.4ml/kg in lateral ear vein,
Obvious expansion does not occur.Radix polygonati officinalis preparation has certain therapeutic action to hypertriglyceridemia.To animal artery atherosis spot
The formation (visually observing) of block has certain mitigation.Radix polygonati officinalis has enhancing humoral immunity and phagocytic function, to immunity of organism work(
There can be adjustment effect.
Dark plum：For rosaceae plant deciduous tree plum Prunus mume (Sieh.) Sieb.et Zucc. immature fruit.Acid,
It is puckery, put down.Return liver, spleen, lung, large intestine channel.Function is astringeed the lung to stop cough, relieving diarrhea with astringents, is promoted the production of body fluid to quench thirst, claming ascaris.Dark plum contains lemon
Acid, malic acid, butanedioic acid, carbohydrate, sitosterol, ceroidlike material and oleanolic acid-like substances.There are strong bactericidal properties and carry
The composition picric acid of high liver function and the almond glucoside with hot analgesic activity, the still superoxides containing greater activity in pulp
Mutase.Clinic is usually used in being used for chronic cough of deficiency lung, protracted dysentery laxation, and abnormal heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache；Ascariasis of biliary tract.
Hawthorn：For for rosaceous plant large-fruited Chinese hawthorn Crataegus pinnatifida Bge.var.major N.E.Br. or hawthorn Crataegus
Pinnatifida Bge. dry mature fruit, remove impurity and the core to come off.Acrid flavour, sweet, slightly warm in nature.Enter spleen, stomach, Liver Channel.
With food digesting stomach fortifying, the effect of scattered stasis.It is clinically used for meat stagnation, gastral cavilty turgor, diarrhea dysentery abdominal pain, blood stasis closed, production
Stasis blocking afterwards, confidant sting, hernia pain；Hyperlipidemia etc..Modern study principle active component is flavones ingredient and triterpenes
Composition, there are left-handed youngster's table caffein, Quercetin, hyperin, ursolic acid, chlorogenic acid, citric acid, citric acid mono-methyl, Chinese holly
Rafter dimethyl phthalate, Trimethyl citrate, flavan polymers etc..Pharmacology confirm have promote digestion, cardiac stimulant, lowering blood pressure and blood fat,
The effects such as anti-oxidant, raising immunity.
The root of kudzu vine：For legume pueraria lobata Pueraria lobata (Willd.) Ohwi. dry root.It is sweet, pungent, it is cool in nature.
Returns spleen, stomach.Function expelling pathogenic factors from muscles and skin is brought down a fever, and is promoted the production of body fluid, promoting eruption, Shengyang Zhixie.It is yellow containing Puerarin, Puerarin xyloside, soybean
Ketone, daidzin and cupreol, arachidic acid etc..Pharmacological research has coronary dilatation to expand blood vessel, and spasmolysis is hypoglycemic, and antipyretic wait is made
With.Clinic is mainly used in fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quenches one's thirst, measles without adequate eruption, hot dysentery, diarrhea；Hypertension
Neck pain etc..
Buddha's hand：For the dry of Rutaceae citrus plant Buddha's hand Citrus medica L.var.sarcodactylis Swingle
Dry fruit.It is pungent, bitter, sour, it is warm-natured.Return liver, spleen, lung channel.Function liver-smoothing, qi-regulating, and stomach and alleviating pain.Containing citropten, 6,
7- dimethoxy coumarins, 3,5,8- trihydroxies -4 ', 7- dimethoxy flavones, limonin, Daucosterol, β-paddy steroid
Alcohol, p-Coumaric acid, palmitic acid, butanedioic acid etc..Pharmacological evaluation prove have anti-inflammatory, relieving asthma, eliminating the phlegm, resist myocardial ischemia,
Suppress the effect such as gastrointestinal smooth muscle spasm.Clinic is usually used in stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, deficiency of food vomiting etc..
Clinical research
Clinical research through inventor to 53 diabetes and Patients with Sjogren Syndrome counts display, uses using prescription of the present invention as base
We's treatment diabetes and Sjogren syndrome are after 1 month, wherein effective (dry, xerophthalmia shape integration improve >=2 grades) 28
Example, effective (dry, xerophthalmia shape integration improve >=1 grade) 25；After taking 3 months, effective 47, effective 6,
According to《New Chinese medicine guideline of clinical investigations》Middle tcm syndrome efficacy evaluation total effective rate is up to 100%, and obvious effective rate is up to 96.2%.
Adverse events are had no during taking.
Typical clinical case
Case 1：
Zhang, female, 51 years old.In November, 2014 goes to a doctor.Main suit is because of frequent dry, eye is dry, cough is coughed up phlegm, easily tired god is tired,
It is Sjogren syndrome in certain hospital diagnosis, through giving the treatment such as glucocorticoid, thymic peptide, the state of an illness is again and again repeatedly.Carry case
Show SSA (+++), SSB (++), ANA (+) 1：160.Inscribe and see the few Tianjin of dry, tongue purple is dark, and tongue is thin, deep thready pulse
It is puckery.Tcm constitution is recognized as yin-deficiency constitution.Tcm diagnosis is that deficiency of both qi and yin and blood stasis type Sjogren syndrome, doctor trained in Western medicine are diagnosed as drying
Syndrome.Therapy, supplementing qi and nourishing yin, promoting blood circulation of promoting the production of body fluid, give 7 doses of this prescription and examine again.Patient feels a mouthful mesh and slightly moistened after 1 week.
No more side effects, continue top.January, Apostomatida became profit, there is tear sometimes.Continue thereafter with and nursed one's health with prescription of the present invention.
Case 2：
Liu, female, 54 years old.In April, 2011 goes to a doctor.Main suit is because of diabetes, and thirsty more drinks, dry mesh is puckery, frequent micturition, back
Ache, merge Sjogren syndrome in certain hospital diagnosis diabetes；Now take melbine, thymic peptide etc..It is empty to carry case display
Abdomen blood glucose 9.42mmol/L, postprandial 2 hours blood glucose 12.53mmol/L, glucose in urine +++；Anti- SS-A, anti-SS-B are positive, ANAl：
160 positive erythrocyte sedimentation rate 49mm/h.The dark pale tongue of lip, thready and hesitant pulse.Tcm constitution is recognized as yin-deficiency constitution.Tcm diagnosis：Deficiency of both qi and yin
Type is quenched one's thirst dry disease, and doctor trained in Western medicine is diagnosed as diabetes, Sjogren syndrome.Therapy, supplementing qi and nourishing yin, promote the production of body fluid to quench thirst, give this prescription 14
Agent is examined again.Fasting blood-glucose 7.87mmol/L after two weeks, glucose in urine ++, thirsty slightly to subtract, mesh slightly moistens, spiritedness.No more side effects, after
Continuous top.Fasting blood-glucose 5.07mmol/L after March, postprandial 2 hours blood glucose 7.43mmol/L, mouth mesh relatively moisten.Continue thereafter with
Prescription conditioning of the present invention.
Prescription of the present invention is effective to the treatment safety of diabetes and Sjogren syndrome in summary, and it is simultaneous to can effectively improve diabetes
The symptom of Sjogren syndrome, refining formula, it is adapted to patient's long-time conditioning to take, is especially suitable for exploitation into Chinese medicine preparation (patent medicine)
Or food.
Embodiment
The present invention is further illustrated with reference to embodiments.
Embodiment 1
Weigh 12 parts of Chinese yam, 10 parts of mulberry fruit, 15 parts of lily, 12 parts of radix polygonati officinalis, 10 parts of dark plum, 15 parts of raw hawthorn, the root of kudzu vine
15 parts, 10 parts of Buddha's hand.
Preparation process：
Each taste Chinese medicine that will be weighed, decoct into decoction by traditional handicraft or Chinese patent medicine preparation technique routinely is processed into Chinese Pharmacopoeia
Defined in the clinical main Chinese patent medicine preparation such as tablet, pill, capsule, granule, powder or oral liquid or according to conventional food
Food is made in product processing technology.To reconcile mouthfeel, appropriate sweetener can be added, for example, Sucralose, honey element, acesulfame potassium,
Steviol glycoside, Momordica grosvenori glucin etc., appropriate acid can be also added, for example malic acid, citric acid etc. carry out entangling taste.
Embodiment 2
Weigh 20 parts of Chinese yam, 20 parts of mulberry fruit, 30 parts of lily, 5 parts of radix polygonati officinalis, 5 parts of dark plum, 10 parts of raw hawthorn, the root of kudzu vine 10
Part, 20 parts of Buddha's hand.
Preparation process is the same as embodiment 1.
Embodiment 3
Weigh 5 parts of Chinese yam, 5 parts of mulberry fruit, 10 parts of lily, 20 parts of radix polygonati officinalis, 20 parts of dark plum, 30 parts of raw hawthorn, the root of kudzu vine 30
Part, 5 parts of Buddha's hand.
Preparation process is the same as embodiment 1.
Embodiment 4
Weigh 6 parts of Chinese yam, 15 parts of mulberry fruit, 25 parts of lily, 6 parts of radix polygonati officinalis, 15 parts of dark plum, 12 parts of raw hawthorn, the root of kudzu vine 20
Part, 18 parts of Buddha's hand.
Preparation process is the same as embodiment 1.
Embodiment 5
Weigh 9 parts of Chinese yam, 6 parts of mulberry fruit, 20 parts of lily, 15 parts of radix polygonati officinalis, 9 parts of dark plum, 15 parts of raw hawthorn, the root of kudzu vine 18
Part, 6 parts of Buddha's hand.
Preparation process is the same as embodiment 1.
Embodiment 6
Weigh 10 parts of Chinese yam, 9 parts of mulberry fruit, 15 parts of lily, 20 parts of radix polygonati officinalis, 10 parts of dark plum, 20 parts of raw hawthorn, the root of kudzu vine
20 parts, 9 parts of Buddha's hand.
Preparation process is the same as embodiment 1.
Embodiment 7
Weigh 15 parts of Chinese yam, 12 parts of mulberry fruit, 18 parts of lily, 12 parts of radix polygonati officinalis, 18 parts of dark plum, 18 parts of raw hawthorn, the root of kudzu vine
15 parts, 12 parts of Buddha's hand.
Preparation process is the same as embodiment 1.
Embodiment 8
Weigh 10 parts of Chinese yam, 15 parts of mulberry fruit, 12 parts of lily, 18 parts of radix polygonati officinalis, 15 parts of dark plum, 12 parts of raw hawthorn, the root of kudzu vine
18 parts, 15 parts of Buddha's hand.
Preparation process is the same as embodiment 1.
Above content is only how to implement example explanation, rather than protection scope of the present invention, this affiliated skill to the present invention
The various modifications or supplement or use similar mode replacement that the technical staff in art field makes to described specific embodiment, as long as
Structure without departing from invention surmounts scope defined in the claims, all should belong to protection scope of the present invention.
Claims (4)
- A kind of 1. Chinese medicinal formulae nursed one's health for diabetes and Sjogren syndrome, it is characterized in that being made up of the Chinese medicine of following parts by weight：5~20 parts of Chinese yam, 5~20 parts of mulberry fruit, 10~30 parts of lily, 5~20 parts of radix polygonati officinalis, 5~20 parts of dark plum, raw mountain 10~30 parts of short, bristly hair or beard, 10~30 parts of the root of kudzu vine, 5~20 parts of Buddha's hand.
- 2. the Chinese medicinal formulae according to claim 1 nursed one's health for diabetes and Sjogren syndrome, it is characterized in that by following The Chinese medicine of parts by weight is made：6~15 parts of Chinese yam, 6~15 parts of mulberry fruit, 12~20 parts of lily, 6~15 parts of radix polygonati officinalis, 6~15 parts of dark plum, raw mountain 12~20 parts of short, bristly hair or beard, 12~20 parts of the root of kudzu vine, 6~15 parts of Buddha's hand.
- 3. the Chinese medicinal formulae according to claim 1 nursed one's health for diabetes and Sjogren syndrome, it is characterized in that by following The Chinese medicine of parts by weight is made：12 parts of Chinese yam, 10 parts of mulberry fruit, 15 parts of lily, 12 parts of radix polygonati officinalis, 10 parts of dark plum, 15 parts of raw hawthorn, the root of kudzu vine 15 Part, 10 parts of Buddha's hand.
- 4. the Chinese medicinal formulae according to claim 1 nursed one's health for diabetes and Sjogren syndrome is preparing medicine and food Application in primary formulation.
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| CN108935779A (en) * | 2018-09-25 | 2018-12-07 | 红河卫生职业学院 | A kind of Sophora viciifolia health protection tea and preparation method thereof |
| CN108935779B (en) * | 2018-09-25 | 2021-07-30 | 红河卫生职业学院 | Nitraria tangutorum bobr health-care tea and preparation method thereof |
| CN112402555A (en) * | 2020-12-04 | 2021-02-26 | 亓鲁光 | Composition for preventing and treating sub-health and diabetes and preparation method thereof |
| CN113577177A (en) * | 2021-07-16 | 2021-11-02 | 中国中医科学院广安门医院 | Traditional Chinese medicine composition containing red peony root and sargentgloryvine stem and preparation method and application thereof |
| CN113577177B (en) * | 2021-07-16 | 2022-05-24 | 中国中医科学院广安门医院 | Traditional Chinese medicine composition containing red peony root and sargentgloryvine stem and preparation method and application thereof |
| CN114569679A (en) * | 2022-03-22 | 2022-06-03 | 邓老金方药业科技有限公司 | Traditional Chinese medicine composition for reducing blood sugar and application thereof |
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Application publication date: 20171208 |