CN107441286A - A kind of relaxing tendons and activating collaterals Ramulus euonymi dipping and preparation method thereof - Google Patents

A kind of relaxing tendons and activating collaterals Ramulus euonymi dipping and preparation method thereof Download PDF

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CN107441286A
CN107441286A CN201710727824.2A CN201710727824A CN107441286A CN 107441286 A CN107441286 A CN 107441286A CN 201710727824 A CN201710727824 A CN 201710727824A CN 107441286 A CN107441286 A CN 107441286A
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parts
raw material
chinese herbal
activating collaterals
relaxing tendons
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廖艳卿
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Abstract

The invention discloses a kind of Ramulus euonymi relaxing tendons and activating collaterals dip, and it is made up of the herbal raw material of following parts by weight：20~30 parts of Ramulus euonymi, 15~25 parts of cassia twig, 3~6 parts of safflower, 10~20 parts of lopseed, 15~20 parts of caulis trachelospermi, 15~25 parts of lycopodium calvatum, 15~20 parts of Herba Lycopi, windproof 9~16 parts, 10~15 parts of Ramulus Taxilli, 5~10 parts of 5~10 parts of rhizoma cyperi and the banksia rose.The invention also discloses the preparation method of Ramulus euonymi relaxing tendons and activating collaterals dip, is crushed, digested by herbal raw material, ultrasound adverse current is extracted, is concentrated under reduced pressure and filtered homogeneous and is made up of master operation.Herbal raw material source of the present invention is wide, and cheap, scientific formulation is reasonable, and preparation technology is simple, and extraction Chinese herbal medicine functional components are high, product safety environmental protection, relaxing tendons and activating collaterals significant effect without any side effects to human body.

Description

A kind of relaxing tendons and activating collaterals Ramulus euonymi dipping and preparation method thereof
Technical field
The invention discloses a kind of dip, more particularly to a kind of Ramulus euonymi relaxing tendons and activating collaterals dip and preparation method thereof, Belong to traditional Chinese medicine field.
Background technology
With the work of the allegro life style of modern and high-strength high-voltage power so that the time of exercise is increasingly Few, neck, shoulder, waist, the numbness patient for the pain that has a pain in the leg gradually increase, and have seriously endangered the health of people.Numbness disease refers to body healthy tendency The perverse trends such as deficiency, weakened defensive QI, wind, cold, wet, heat are taken advantage of a weak point, and are caused qi and blood stagnation, obstruction of meridians and collaterals, are caused related system disease The general name of disease.Narrow sense numbness disease, that is, refer to limbs channels and collaterals numbness therein, with muscle, muscles and bones, joint occur pain, numbness, weigh, Joint stuffiness, or even the scorching hot disease for main clinical manifestation of arthrocele.
Numbness disease can use Chinese and Western medicine anti symptom treatment, can take some analgesic-antipyretic during such as pain, B races can be selected in numb person Vitamin medicaments, but drug oral, gastrointestinal reaction is obvious, larger to liver, renal damage；Arthroncus has hydrops, and person can give It is local to extract the therapy such as hydrops or partial closure, but the treatment method is undesirable, and the state of an illness easily recurs.Or the method with physiotherapy, Galvanoiontophoresis method has given full play to the effect of medicine, but is liquid because importing medicine, and volatile, drug effect is not held Long, the therapeutic effect of this method is limited.It is certain that other can use the treatment methods such as ultraviolet, infrared ray, microwave, laser to have Effect, but have limitation.Because numbness disease is common disease, the incidence of disease is very high, more stubborn and stupid, takes in general treatment method most It is not easy to cure, causes that the course of disease is long, cost is more, rehabilitation is slow, heavier burden is brought to patient and family members.
Dipping has original effect to human body, with a history of thousands of years in China, since ancient times always by medical field weight Depending on.Dipping method is one of external therapy, i.e., a variety of with decoction or a kind of method containing decoction water washing bath whole body or part, its form It is various.In general, medicine acts on whole body fleshy exterior, part, affected part to the dipping mechanism of action, and through absorbing, circulation channels and collaterals blood vessels are interior Up to internal organs, from outward appearance to inner essence, thus effect is produced.Dipping bathing, can play dredging the channel, activate blood circulation and disperse blood clots, wind dispelling cold dispelling, heat-clearing solution Poison, swelling and pain relieving, negative and positive are adjusted, coordinates internal organs, current qi and blood, moisten the health maintenance effects such as foster whole body.Dipping avoids medicine to spleen The stimulation of stomach and the infringement to liver, effective ingredient is absorbed by skin to play effect, be the various chronic diseases of preventing and treating Disease and the Perfected process of health care.
Chinese herbal medicine is the rarity of Chinese traditional culture, proves that a variety of Chinese herbal medicines have in practice and enhances metabolism, changes Kind blood circulation, relaxing tendons and activating collaterals, active, expelling wind and clearing away cold, expelling pathogenic factors from muscles and skin dehumidifying, strengthening the muscles and bones and other effects are made inquiries, therefore, should by Chinese herbal medicine Various numbness diseases are treated for relaxing tendons and activating collaterals to be of great significance for improving national life quality, guarantee living safety tool, But current Chinese herbal medicine relaxing tendons and activating collaterals dipping not yet realizes scale and industrialization in application, and subject matter is that Chinese herbal medicine compatibility does not conform to Reason, the drawback such as functional component recovery rate is low, be difficult to industrialized production, effect is not notable, therefore develop new relaxing tendons and activating collaterals medicine Bath has important practical significance.
The content of the invention
It is an object of the invention to the above mentioned problem according to existing for existing relaxing tendons and activating collaterals product, a kind of Ramulus euonymi relaxing muscles and tendons is developed Promoting blood circulation dip, people is passed through dipping to promote body metabolism, improve body blood circulation, relaxing tendons and activating collaterals, make inquiries work Network, expelling wind and clearing away cold, expelling pathogenic factors from muscles and skin dehumidifying, strengthening the muscles and bones, the cause of disease is dispelled from root, allow people away from the sick puzzlement of numbness.
To achieve these goals, the present invention uses following technical scheme：
A kind of Ramulus euonymi relaxing tendons and activating collaterals dip, is made up of the herbal raw material of following parts by weight：20~30 parts of Ramulus euonymi, cassia twig 15~25 parts, 3~6 parts of safflower, 10~20 parts of lopseed, 15~20 parts of caulis trachelospermi, 15~25 parts of lycopodium calvatum, Herba Lycopi 15~20 Part, windproof 9~16 parts, 10~15 parts of Ramulus Taxilli, 5~10 parts of 5~10 parts of rhizoma cyperi and the banksia rose.
The preparation method of Ramulus euonymi relaxing tendons and activating collaterals dip of the present invention, comprises the following steps：
（1）Stock：The impurity in herbal raw material is rejected, goes mouldy with after infested raw material, is stocked up according to aforementioned proportion；
（2）Feedstock treating：Herbal raw material is cleaned up, at 70~85 DEG C, after air blast drying, pulverizer crushes, and crosses 60 ~100 mesh sieves, mix, obtain composite Chinese herbal raw material；
（3）Enzymolysis：By step（2）Gained composite Chinese herbal raw material adds water to solid-to-liquid ratio 1：2~3, by 1.5~2.0 g/L, 2.0 ~2.5 g/L ratios add non-starch polysaccharide enzyme, cellulase respectively, under the effect of 500 ~ 800 W ultrasonic assistants, 30~ The min of coordinated enzymatic hydrolysis 60~80 under the conditions of 50 DEG C；
（4）Ultrasonic adverse current is extracted：By step（3）The mixed liquor obtained after enzymolysis, 4~6 times of 50~60% ethanol are added, are put into In ultrasonic continuous countercurrent extractor, under the effect of 600 ~ 800 W ultrasonic assistants, after adverse current extracts 30 ~ 45 min, excessively 120 ~ 180 mesh filter clothes obtain water extract.Filter residue adds 2 ~ 4 times of 50~60% ethanol, carries out ultrasonic continuous countercurrent extraction in the same way, Filter to get filtrate, it is extracts of Chinese herbal medicine to merge extract solution twice；
（5）It is concentrated under reduced pressure：By step（4）The extracts of Chinese herbal medicine of gained at 60~75 DEG C of temperature, vacuum -0.06~- It is evaporated under reduced pressure under 0.085 MPa, reclaims the ethanol in extracts of Chinese herbal medicine to without alcohol taste, obtain removal ethanol Chinese herbal medicine and carry Take liquid；
（6）Filtering：By step（5）Gained extracts of Chinese herbal medicine, impurity and insoluble matter therein are filtered to remove through diatom filter Produce Ramulus euonymi relaxing tendons and activating collaterals dip.
The present invention provides a kind of Ramulus euonymi relaxing tendons and activating collaterals dip, the characteristic of each Chinese herbal medicine in combined formulation, using Chinese medical discrimination Theory is developed, and scientific formulation is reasonable, is acted synergistically between each component, proves the present invention to various wind-cold-dampness arthralgias by long-term use Card, including pain in the back, skelagia, cervical spondylopathy, scapulohumeral periarthritis and femoral head disease, spinal canal stenosis, osteoproliferation have the effect of good.This hair Bright advantage is：（（1）Product is not required to by body absorption using medicine during dipping, and drug effect is directly acted on into affected part, safety Environmental protection, mild in medicine property and, it is without any side effects to human body；（2）Product has pleasant Chinese herbal medicine delicate fragrance, easy to use, during use This product only need to be taken by 1：300~600 ratios are called in heating bath water, can carry out immersion bathing；（3）Added merely with medical bathing powder Compare, the present invention uses raw material to crush enzymolysis, the extraction of ultrasound adverse current, filtering homogeneous as main preparation section, in effectively improving Herbal medicine functional components, relaxing tendons and activating collaterals effect are notable；（4）Raw material sources are wide in the present invention, cheap, production and processing technology letter It is single, it is adapted to large-scale production.
Embodiment
Below by embodiment, the present invention will be further described.In the present invention, if not refering in particular to, Suo Youbai Point ratio is unit of weight, and all devices and raw material are commercially available or the industry is commonly used, in following embodiments Method, it is this area conventional method unless otherwise instructed.
Embodiment 1
A kind of Ramulus euonymi relaxing tendons and activating collaterals dip, is made up of the herbal raw material of following each component：Ramulus euonymi, cassia twig, safflower, thoroughly Bone grass, caulis trachelospermi, lycopodium calvatum, Herba Lycopi is windproof, Ramulus Taxilli, rhizoma cyperi and the banksia rose.Each component is specific with such as in herbal raw material Shown in table 1.
The preparation method of Ramulus euonymi relaxing tendons and activating collaterals dip of the present invention, comprises the following steps：
（1）Stock：The impurity in herbal raw material is rejected, goes mouldy with after infested raw material, is stocked up according to aforementioned proportion；
（2）Feedstock treating：Herbal raw material is cleaned up, at 82 DEG C, after air blast drying, pulverizer crushes, and crosses 70 mesh Sieve, mix, obtain composite Chinese herbal raw material；
（3）Enzymolysis：By step（2）Gained composite Chinese herbal raw material adds water to solid-to-liquid ratio 1：2, in 1.60 g/L, 2.0 g/L ratios Non-starch polysaccharide enzyme, cellulase are added respectively, under the effect of 700 W ultrasonic assistants, the coordinated enzymatic hydrolysis 60 under the conditions of 40 DEG C min；
（4）Ultrasonic adverse current is extracted：By step（3）The mixed liquor obtained after enzymolysis, 6 times of 50% ethanol is added, be put into ultrasonic continuous In countercurrent extraction machine, under the effect of 750 W ultrasonic assistants, after adverse current extracts 40 min, cross 120 mesh filter clothes and obtain water extract. Filter residue adds 3 times of 58% ethanol, carries out ultrasonic continuous countercurrent extraction in the same way, filters to get filtrate, and merges extract solution twice and is For extracts of Chinese herbal medicine；
（5）It is concentrated under reduced pressure：By step（4）The extracts of Chinese herbal medicine of gained enters at 72 DEG C of temperature under the MPa of vacuum -0.06 Row is evaporated under reduced pressure, and is reclaimed the ethanol in extracts of Chinese herbal medicine to without alcohol taste, is obtained removing ethanol extracts of Chinese herbal medicine；
（6）Filtering：By step（5）Gained extracts of Chinese herbal medicine, impurity and insoluble matter therein are filtered to remove through diatom filter Produce Ramulus euonymi relaxing tendons and activating collaterals dip.
Embodiment 2
A kind of Ramulus euonymi relaxing tendons and activating collaterals dip, is made up of the herbal raw material of following each component：Ramulus euonymi, cassia twig, safflower, thoroughly Bone grass, caulis trachelospermi, lycopodium calvatum, Herba Lycopi is windproof, Ramulus Taxilli, rhizoma cyperi and the banksia rose.Each component is specific with such as in herbal raw material Shown in table 1.
The preparation method of Ramulus euonymi relaxing tendons and activating collaterals dip of the present invention, comprises the following steps：
（1）Stock：The impurity in herbal raw material is rejected, goes mouldy with after infested raw material, is stocked up according to aforementioned proportion；
（2）Feedstock treating：Herbal raw material is cleaned up, at 77 DEG C, after air blast drying, pulverizer crushes, and crosses 80 mesh Sieve, mix, obtain composite Chinese herbal raw material；
（3）Enzymolysis：By step（2）Gained composite Chinese herbal raw material adds water to solid-to-liquid ratio 1：2.5, by 1.8 g/L, 2.2 g/L ratios Example adds non-starch polysaccharide enzyme, cellulase respectively, under the effect of 700 W ultrasonic assistants, the coordinated enzymatic hydrolysis under the conditions of 35 DEG C 70 min；
（4）Ultrasonic adverse current is extracted：By step（3）The mixed liquor obtained after enzymolysis, 6 times of 55% ethanol is added, be put into ultrasonic continuous In countercurrent extraction machine, under the effect of 700 W ultrasonic assistants, after adverse current extracts 36 min, cross 150 mesh filter clothes and obtain water extract. Filter residue adds 2 times of 55% ethanol, carries out ultrasonic continuous countercurrent extraction in the same way, filters to get filtrate, and merges extract solution twice and is For extracts of Chinese herbal medicine；
（5）It is concentrated under reduced pressure：By step（4）The extracts of Chinese herbal medicine of gained enters at 68 DEG C of temperature under the MPa of vacuum -0.07 Row is evaporated under reduced pressure, and is reclaimed the ethanol in extracts of Chinese herbal medicine to without alcohol taste, is obtained removing ethanol extracts of Chinese herbal medicine；
（6）Filtering：By step（5）Gained extracts of Chinese herbal medicine, impurity and insoluble matter therein are filtered to remove through diatom filter Produce Ramulus euonymi relaxing tendons and activating collaterals dip.
Embodiment 3
A kind of Ramulus euonymi relaxing tendons and activating collaterals dip, is made up of the herbal raw material of following each component：Ramulus euonymi, cassia twig, safflower, thoroughly Bone grass, caulis trachelospermi, lycopodium calvatum, Herba Lycopi is windproof, Ramulus Taxilli, rhizoma cyperi and the banksia rose.Each component is specific with such as in herbal raw material Shown in table 1.
The preparation method of Ramulus euonymi relaxing tendons and activating collaterals dip of the present invention, comprises the following steps：
（1）Stock：The impurity in herbal raw material is rejected, goes mouldy with after infested raw material, is stocked up according to aforementioned proportion；
（2）Feedstock treating：Herbal raw material is cleaned up, at 72 DEG C, after air blast drying, pulverizer crushes, and crosses 90 mesh Sieve, mix, obtain composite Chinese herbal raw material；
（3）Enzymolysis：By step（2）Gained composite Chinese herbal raw material adds water to solid-to-liquid ratio 1：3, in 2.0 g/L, 2.4 g/L ratios Non-starch polysaccharide enzyme, cellulase are added respectively, under the effect of 800 W ultrasonic assistants, the coordinated enzymatic hydrolysis 80 under the conditions of 45 DEG C min；
（4）Ultrasonic adverse current is extracted：By step（3）The mixed liquor obtained after enzymolysis, 4 times of 60% ethanol is added, be put into ultrasonic continuous In countercurrent extraction machine, under the effect of 650 W ultrasonic assistants, after adverse current extracts 32 min, cross 180 mesh filter clothes and obtain water extract. Filter residue adds 4 times of 52% ethanol, carries out ultrasonic continuous countercurrent extraction in the same way, filters to get filtrate, and merges extract solution twice and is For extracts of Chinese herbal medicine；
（5）It is concentrated under reduced pressure：By step（4）The extracts of Chinese herbal medicine of gained enters at 64 DEG C of temperature under the MPa of vacuum -0.08 Row is evaporated under reduced pressure, and is reclaimed the ethanol in extracts of Chinese herbal medicine to without alcohol taste, is obtained removing ethanol extracts of Chinese herbal medicine；
（6）Filtering：By step（5）Gained extracts of Chinese herbal medicine, impurity and insoluble matter therein are filtered to remove through diatom filter Produce Ramulus euonymi relaxing tendons and activating collaterals dip.
The composition and ratio of each embodiment herbal raw material of table 1.
Sequence number Component Embodiment 1 Embodiment 2 Embodiment 3
1 Ramulus euonymi（Part） 23 26 28
2 Cassia twig（Part） 23 21 18
3 Safflower（Part） 5 4 6
4 Lopseed（Part） 14 17 19
5 Caulis trachelospermi（Part） 19 17 15
6 Lycopodium calvatum（Part） 17 24 20
7 Herba Lycopi（Part） 18 16 17
8 It is windproof（Part） 13 11 15
9 Ramulus Taxilli（Part） 12 13 15
10 Rhizoma cyperi（Part） 8 7 6
11 The banksia rose（Part） 9 7 8
12 Summation（Part） 161 163 167
Although to reach illustration purpose, described above is the preferred embodiments of the present invention, is not intended to limit the invention, to the greatest extent The present invention is described in detail with reference to the foregoing embodiments for pipe, and for those skilled in the art, it still can be with The technical scheme recorded to foregoing embodiments is modified, or carries out equivalent substitution to which part technical characteristic.It is all Within the spirit and principles in the present invention, any modification, equivalent substitution and improvements made etc., the protection of the present invention should be included in Within the scope of.

Claims (2)

1. a kind of Ramulus euonymi relaxing tendons and activating collaterals dip, it is characterised in that be made up of the herbal raw material of following parts by weight：Ramulus euonymi 20~30 parts, 15~25 parts of cassia twig, 3~6 parts of safflower, 10~20 parts of lopseed, 15~20 parts of caulis trachelospermi, lycopodium calvatum 15~25 Part, 15~20 parts of Herba Lycopi, windproof 9~16 parts, 10~15 parts of Ramulus Taxilli, 5~10 parts of 5~10 parts of rhizoma cyperi and the banksia rose.
2. a kind of preparation method of Ramulus euonymi relaxing tendons and activating collaterals dip as claimed in claim 1, it is characterised in that including following Step：
（1）Stock：The impurity in herbal raw material is rejected, goes mouldy with after infested raw material, is stocked up according to aforementioned proportion；
（2）Feedstock treating：Herbal raw material is cleaned up, at 70~85 DEG C, after air blast drying, pulverizer crushes, and crosses 60 ~100 mesh sieves, mix, obtain composite Chinese herbal raw material；
（3）Enzymolysis：By step（2）Gained composite Chinese herbal raw material adds water to solid-to-liquid ratio 1：2~3, by 1.5~2.0 g/L, 2.0 ~2.5 g/L ratios add non-starch polysaccharide enzyme, cellulase respectively, under the effect of 500 ~ 800 W ultrasonic assistants, 30~ The min of coordinated enzymatic hydrolysis 60~80 under the conditions of 50 DEG C；
（4）Ultrasonic adverse current is extracted：By step（3）The mixed liquor obtained after enzymolysis, 4~6 times of 50~60% ethanol are added, are put into In ultrasonic continuous countercurrent extractor, under the effect of 600 ~ 800 W ultrasonic assistants, after adverse current extracts 30 ~ 45 min, excessively 120 ~ 180 mesh filter clothes obtain water extract；Filter residue adds 2 ~ 4 times of 50~60% ethanol, carries out ultrasonic continuous countercurrent extraction in the same way, Filter to get filtrate, it is extracts of Chinese herbal medicine to merge extract solution twice；
（5）It is concentrated under reduced pressure：By step（4）The extracts of Chinese herbal medicine of gained at 60~75 DEG C of temperature, vacuum -0.06~- It is evaporated under reduced pressure under 0.085 MPa, reclaims the ethanol in extracts of Chinese herbal medicine to without alcohol taste, obtain removal ethanol Chinese herbal medicine and carry Take liquid；
（6）Filtering：By step（5）Gained extracts of Chinese herbal medicine, impurity and insoluble matter therein are filtered to remove through diatom filter Produce Ramulus euonymi relaxing tendons and activating collaterals dip.
CN201710727824.2A 2017-08-23 2017-08-23 A kind of relaxing tendons and activating collaterals Ramulus euonymi dipping and preparation method thereof Pending CN107441286A (en)

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Application publication date: 20171208