CN107441019A - A kind of pet toothpaste and preparation method thereof - Google Patents
A kind of pet toothpaste and preparation method thereof Download PDFInfo
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- CN107441019A CN107441019A CN201710675356.9A CN201710675356A CN107441019A CN 107441019 A CN107441019 A CN 107441019A CN 201710675356 A CN201710675356 A CN 201710675356A CN 107441019 A CN107441019 A CN 107441019A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The present invention relates to a kind of household chemicals, more particularly to a kind of pet dentifrice and preparation method thereof.The pet dentifrice includes 80 600 parts of rubbing agent, 50 300 parts of NMF, 0 10 parts of flavouring agent, 10 50 parts of foaming agent, 5 30 parts of thickener, function intensified 4 20 parts of composition, 16 parts of stabilizer, wherein, the function intensified composition is the mixture of active ingredient of Chinese herbs and ferment.Toothpaste of the present invention can be exclusively used in pet, particularly dog cat etc., can effectively pre- anti-pet calculus dentalis, alleviate periodontitis and the pre- anti-caries of energy, swallow lotion and have no toxic side effect, the oral icrocirculation that can improve pet is coordinated by each component, prevent canker sore, and can effectively suppress and kill main cariogenic bacteria, there is inhibitory action to bacterial plaque forming process, the multiple oral diseases such as the gingivitis of pet can be prevented and treated.The present invention does not injure without preservative etc. is added to the body of pet, and this formula, can make the long shelf-life of toothpaste, and stability is good.The present invention implements simple, the suitable pet routine use of formula safety.
Description
Technical field
The present invention relates to field of daily chemicals, and in particular to a kind of pet toothpaste and preparation method thereof.
Background technology
Because food soft and that stickiness is larger is eaten for a long time in domestic pets (dog, cat etc.), and oral cavity is infrequently cleaned, doted on
Thing dental surface often has bacterium and its product tack deposition and and then formation bacterial plaque.Bacterial plaque stickiness is very big, is easily adsorbed with
Machine thing and inorganic matter and form calculus.Calculus dentalis is more easy to adsorb more bacteriums and mycin in itself, with bacterium and its dental calculus
Local long-time stimulus, gum can be made to be inflamed, tooth peripheral tissue edema, hyperemia occur, gingival margin is rotten to the corn, bleeding.With
Gingivitis continues to develop, and can trigger tooth surrounding tissue pyorrhea, halitosis, alveolus osteoclasia, gingival atrophy, Root exposnre occurs,
Periodontitis is showed, is further development of tooth mobility.Due to the repeated infection of gum, cause bacterium to enter blood, cause ephritis,
The disease of the serious threat to life such as heart film inflammation.
The occurrence and development of pre- anti-pet calculus dentalis, can be realized by different approaches, such as be brushed teeth, using the viscous of removal calculus dentalis
Property ointment or pet clinic carry out toothwash.And adhesive plaster may be to the health of pet, particularly appetite causes one
It is fixing to ring；Pet toothwash needs general anesthesia, and general anesthesia has certain injury to pet or even has sequelae.Therefore, using conjunction
Suitable toothpaste is regular to pet to carry out the method that oral cleaning is also the pre- anti-pet calculus dentalis for being easiest to realization.
The composition of toothpaste is extremely complex, is largely chemical composition, rubbing agent selection silica, have containing foaming agent and
Reactive blowing agent two types, all contain preservative, and the taste of toothpaste, odor type can not be received by pet.In addition, dote on
Thing can swallow the phenomenon of toothpaste unavoidably during brushing teeth, and pet body may be brought with toothpaste using common people
Harmful effect.Therefore, the cleaning of pet teeth needs targetedly toothpaste.
The content of the invention
It is an object of the invention to provide a kind of pet toothpaste and preparation method thereof.
To achieve the above object, the present invention adopts the following technical scheme that：
The pet includes following component with toothpaste：Rubbing agent 80-600 parts, NMF 50-300 parts, flavouring agent 0-10
Part, foaming agent 10-50 parts, thickener 5-30 parts, function intensified composition 4-20 parts, stabilizer 1-6 parts, wherein, the function is strong
Chemical conversion is divided into the mixture of active ingredient of Chinese herbs and ferment.
It is preferred that total weight parts are 1000 parts, surplus is deionized water.
On rubbing agent, the rubbing agent is preferably two or three in bone meal, cellulose and calcium phosphate dibasic dihydrate；
Wherein, the one or more that bone meal is preferably selected in fishbone dust, bovine bone powder, Os Sus domestica powder, chick bone powder, the bone meal
Preferable ph is 7.5-9；
The bone meal not only has the function that rubbing agent and function in this formula, coordinates with toothbrush, by rubbing action,
Remove tooth mycoderm；It is also the material composition of pet mineral feed simultaneously, provides macro minerals element for pet, play prevention and dote on
Thing mineral element shortage, rickets, osteomalacia etc..
The cellulose preferably selects insoluble diedairy fiber, can be promoted to digest defecation by pets.
By weight, it is preferred that the content of bone meal is the 15%-75% of rubbing agent total amount, and/or, content of cellulose
For the 10-25% of rubbing agent total amount, and/or, calcium phosphate dibasic dihydrate content is the 5-15% of rubbing agent total amount.
When from the component a period of time of bone meal as rubbing agent, the preferable amount of the bone meal is rubbing agent total amount
70%.
When from the component a period of time of cellulose as rubbing agent, the preferable amount of cellulose is rubbing agent total amount
15%.
It is when selecting component a period of time, the preferable amount of calcium phosphate dibasic dihydrate of the calcium phosphate dibasic dihydrate as rubbing agent
The 10% of rubbing agent total amount.
On NMF, preferably from one kind in D-sorbite, glycerine, propane diols, polyethylene glycol, polyalcohol or more
Kind, play wetting agent in inventive formulation.
On flavouring agent, it is preferred that the flavouring agent is that beef flavour flavouring agent, chicken flavor flavouring agent, edible oiliness are with sweet and sour flavor
One or more in taste agent (such as salmon, cod, tuna), vanilla flavored aromatic, play flavour enhancing in inventive formulation
Effect, makes pet be easier to receive the flavor of toothpaste.Preferably, dog uses beef flavour flavouring agent, chicken flavor flavouring agent with toothpaste；
Cat is with toothpaste using edible oiliness fish scent dispenser；Rodent toothpaste uses beef flavour flavouring agent or vanilla flavored aromatic, more
Easily received by pet.
On foaming agent, the foaming agent is preferably APG or sodium lauroyl sarcosine, in inventive formulation
Main function be to ensure that powder disperses not conglomeration in friction process, in unlikely cohesive oral cavity and dental surface；Also there is hair simultaneously
Bubble, the function of bactericidal.
On thickener, the thickener is preferably natural plant, one kind or more in xanthans, carragheen, agar
The mixture of kind, act what is thickened and bond in inventive formulation.
On function intensified composition, the function intensified composition includes the mixture of active ingredient of Chinese herbs and ferment.It is preferred that
, the ratio of the active ingredient of Chinese herbs and ferment is 1:5-5:1.
It is further preferred that the active ingredient of Chinese herbs includes：Propolis, Caulis Perillae, it is preferred that also including windproof, wild pepper,
At least one of notopterygium root, asarum, radix scutellariae, Chinese gall；It is further preferred that the composition includes propolis 2.5-3 parts, Caulis Perillae
2.5-3 parts, windproof 0.1-0.5 parts, wild pepper 0.1-0.5 parts, notopterygium root 0.1-0.3 parts, asarum 0.1-0.3 parts, radix scutellariae 0.5-2 parts,
Chinese gall 0.5-1 parts.
And the cooperation of propolis and Caulis Perillae and other active ingredient of Chinese herbs is used, there is alleviation effect for pet toothache.
Propolis of the present invention can use known propolis as raw material, it is preferred that propolis of the present invention is ethanol
Extract, extract to obtain using willow type propolis as raw material；It is further preferred that propolis extracted with alcohol of the present invention
Extract to obtain using Populus in China type propolis as raw material.Extracts active ingredients are carried out to propolis using ethanol as solvent can use this
Field conventional technology.
Remaining active ingredient of Chinese herbs is obtained by grinding, mixing.
The present invention also removes antiseptic in conventional toothpaste, the toothpaste that the use of the active ingredient of Chinese herbs significantly improves
Inoxidizability, make its shelf-life elongated.
Preferably, the ferment is protease, lipase, cellulase, amylase, lysozyme, lactoperoxidase, Portugal
Carbohydrate oxidase, more than the one or more in superoxide dismutase, oxidoreducing enzyme.The component of ferment is preferably：Protease 1-3
Part, lipase 0.5-3 parts, cellulase 0-2 parts, amylase 0.5-3 parts, lysozyme 0.5-1 parts, lactoperoxidase 0.5-1
Part, glucose oxidase 0-1 parts, more than superoxide dismutase 0.5-1 parts, oxidoreducing enzyme 0.5-1 parts；
More preferably：Protease 1-3 parts, lipase 0.5-3 parts, cellulase 1.5-2, amylase 0.5-3 parts, lysozyme
0.5-1 parts, lactoperoxidase 0.5-1 parts, glucose oxidase 0.5-1, more than superoxide dismutase 0.5-1 parts, redox
Enzyme 0.5-1 parts.
Addition ferment can targetedly aid in decomposing the albumen, fat, cellulose, starch that diet remains in pet's oral cavity
Deng, and other such as lysozymes are to safeguarding that pet's oral cavity health also has obvious benefit.
Ferment is engaged with active ingredient of Chinese herbs, can anti-inflammatory, antibacterial, due to the present invention pet dentifrice can gulp down
It pharynx, can more enter inside pet, so as to improve the function of intestinal canal of pet, strengthen constitution, strengthen resistance of the pet to disease
Power.
On stabilizer, preferably tetrasodium pyrophosphate.
The pet dentifrice of the present invention, those skilled in the art can be selected according to said components and ratio range, herein
It is not limited.
The present invention provides a kind of optimization formula of pet dentifrice in the lump, as follows：
A kind of pet toothpaste, it is characterised in that：In parts by weight, total weight parts are 1000 parts, and formula is as follows：
Bone meal 120-147 parts, calcium phosphate dibasic dihydrate 30-40 parts, cellulose 30-55 parts, glycerine 200-300 parts, fragrance
Agent 0-5 parts, foaming agent 25-35 parts, xanthans 15-25 parts, active ingredient of Chinese herbs 8-10 parts, ferment 5-10 parts, tetrasodium pyrophosphate 3
Part, surplus is deionized water；
The active ingredient of Chinese herbs includes：Propolis 2.5-3 parts, Caulis Perillae 2.5-3 parts, windproof 0.5 part, 0.5 part of wild pepper, Qiang
0.2-0.3 parts living, asarum 0.2-0.3 parts, radix scutellariae 1-1.5 parts, Chinese gall 0.6-1 parts；
The ferment includes：Protease 1-3 parts, lipase 1-2.5 parts, amylase 0.5-2.5 parts, lysozyme 0.5-1 parts,
Lactoperoxidase 0.5-1 parts, more than superoxide dismutase 0.5-1 parts, 0.5 part of oxidoreducing enzyme, glucose oxidase 0-1 parts,
Cellulase 0-2 parts.
Reasonable using the pet dentifrice cost of this formula, the lotion produced is uniform, good stability, is selected according to different pets
Different flavouring agents is selected, pet acceptance is high, and easy to use, and effect is good, not only alleviates pet's oral cavity disease, moreover it is possible to which help is doted on
Thing improves constitution.
Toothpaste of the present invention can be exclusively used in pet, particularly dog cat etc., can effectively pre- anti-pet calculus dentalis, alleviate tooth
The all scorching and pre- anti-caries of energy, swallow lotion and have no toxic side effect, and the oral icrocirculation that can improve pet, prevention are coordinated by each component
Canker sore, and can effectively suppress and kill main cariogenic bacteria, there is inhibitory action to bacterial plaque forming process, pet can be prevented and treated
The multiple oral diseases such as gingivitis.The present invention does not injure without preservative etc. is added to the body of pet, and this formula,
The long shelf-life of toothpaste can be made, and stability is good.The present invention implements simple, the suitable pet routine use of formula safety.
The present invention provides the preparation method of above-mentioned pet toothpaste in the lump, comprises the following steps：
1) foaming agent, active ingredient of Chinese herbs are mixed with NMF, high-speed stirred, is prepared as solution or suspension, obtains
Mixture A；
2) ferment is dissolved in the water, and mixed with thickener and flavouring agent, obtain mixture B；
3) the mixture B is added in mixture A, is dispersed with stirring uniformly, adds rubbing agent, be dispersed with stirring uniformly；
4) continue stirring under vacuum and lotion is made, sterile filling produces.
Preferably, the step 4) vacuum condition is 0.08-0.12MPa.
The present invention also provides a kind of application method of above-mentioned pet toothpaste, and application method is as follows：By the lotion of toothpaste
It is applied on the tooth of pet, can be used cooperatively using special pet toothbrush, friction effect of the enhancing lotion of toothpaste on tooth
Fruit.
Embodiment
Following examples are used to illustrate the present invention, but are not limited to the scope of the present invention.
The dog toothpaste of embodiment 1
Dog is included with toothpaste described in the present embodiment：By weight, total number 1000, wherein 210 parts of rubbing agent, moisturizing
250 parts of agent, 5 parts of flavouring agent, 30 parts of foaming agent, 20 parts of thickener, function intensified 20 parts of composition, 3 parts of stabilizer, surplus for go from
Sub- water.
Wherein, the rubbing agent is from bovine bone powder and the mixture of calcium phosphate dibasic dihydrate, wherein ox bone powder content
70%, calcium phosphate dibasic dihydrate content is 15%；Content of cellulose is 15%；The NMF selects glycerine；The flavouring agent
From beef flavour flavouring agent；The foaming agent selects sodium lauroyl sarcosine；The thickener selects xanthans；Stabilizer is selected
Tetrasodium pyrophosphate；The functional chemical conversion point includes active ingredient of Chinese herbs and ferment, ratio 1:1, wherein active Chinese drug component point
Including：3 parts of propolis, 3 parts of Caulis Perillae, windproof 0.5 part, 0.5 part of wild pepper, 0.25 part of notopterygium root, 0.25 part of asarum, 1.5 parts of radix scutellariae, five
1 part of gall nut, the ferment are 2 parts of protease, 2 parts of lipase, 2 parts of cellulase, 1 part of amylase, 0.5 part of lysozyme, glucose
0.5 part of oxidizing ferment, more than 0.5 part of superoxide dismutase, 0.5 part of oxidoreducing enzyme, 1 part of lactoperoxidase；Surplus for go from
Sub- water.
This toothpaste can effectively pure and fresh dog implication, beef flavour is highly susceptible to being received by dog, and active ingredient of Chinese herbs can effectively be gone
Removing abnormal flavor in oral cavity, complete cleaning simultaneously, appropriate supplement calcium, effectively pre- anti-tartar generation, tooth-whitening, solving gum and ask
Topic, dispels bacterial plaque, natural formula edible.In this formula, component and the other components of ferment are coordinated, and are particularly adapted to
Canine, canine can be promoted to digest and assimilate nutriment, tooth can not only be cleaned, moreover it is possible to help canine to improve a variety of digestive problems.
The dog of embodiment 2 toothpaste preparation method
The present embodiment provides a kind of preparation method of the toothpaste of dog as described in Example 1, and its step is as follows：
1) foaming agent, active ingredient of Chinese herbs are mixed with NMF, high-speed stirred, be prepared as molten according to selected parts by weight
Liquid or suspension, obtain mixture A1；
2) ferment is dissolved in the water according to selected parts by weight, and mixed with thickener and flavouring agent, obtain mixture
B1；
3) the mixture B1 is added in mixture A1, is dispersed with stirring the rubbing agent for uniformly, adding selected parts by weight, stirs
Mix and be uniformly dispersed；
4) continue stirring in the case where vacuum condition is 0.08-0.12MPa and lotion is made, sterile filling produces.
The cat toothpaste of embodiment 3
Cat is included with toothpaste described in the present embodiment：By weight, total number 1000, wherein 210 parts of rubbing agent, moisturizing
250 parts of agent, 5 parts of flavouring agent, 30 parts of foaming agent, 20 parts of thickener, function intensified 20 parts of composition, 3 parts of stabilizer, surplus for go from
Sub- water.
Wherein, the rubbing agent is from fishbone dust and calcium phosphate dibasic dihydrate and the mixture of cellulose, wherein bovine bone powder
Content is 72%, and calcium phosphate dibasic dihydrate content is 15%, and NMF described in cellulose 13% selects glycerine；The flavouring agent choosing
With salmon taste flavouring agent；The foaming agent selects sodium lauroyl sarcosine；The thickener selects xanthans；Stabilizer is selected
Tetrasodium pyrophosphate；The functional chemical conversion point includes active ingredient of Chinese herbs and ferment, ratio 1：1, wherein active Chinese drug component into
Chinese medicine, which lives in dividing, to be included：3 parts of propolis, 3 parts of Caulis Perillae, windproof 0.5 part, 0.5 part of wild pepper, 0.25 part of notopterygium root, 0.25 part of asarum, radix scutellariae
1.5 parts, 1 part of Chinese gall, the ferment are protease 3 part, 2.5 parts of lipase, amylase 2 .5 parts, 0.5 part of lysozyme, newborn mistake
0.5 part of oxide enzyme, more than 0.5 part of superoxide dismutase, 0.5 part of oxidoreducing enzyme；Surplus is deionized water.
This toothpaste can effectively pure and fresh cat implication, flesh of fish taste is highly susceptible to being received by cat, is reduced to the difficulty in cat cleaning oral cavity
Degree, can effectively be suppressed using this toothpaste and kill main cariogenic bacteria, have inhibitory action to bacterial plaque forming process, and can adjust cat mouth
The activity of chamber flora；And there is certain analgesic effect；Toothache for cat has alleviation effect, prevents the diseases such as gingivitis and the stomatitis of cat
Disease, it is effectively improved oral icrocirculation.
The cat of embodiment 4 toothpaste preparation method
The present embodiment provides a kind of preparation method of the toothpaste of cat as described in Example 3, and its step is as follows：
1) foaming agent, active ingredient of Chinese herbs are mixed with NMF, high-speed stirred, be prepared as molten according to selected parts by weight
Liquid or suspension, obtain mixture A2；
2) ferment is dissolved in the water according to selected parts by weight, and mixed with thickener and flavouring agent, obtain mixture
B2；
3) the mixture B2 is added in mixture A2, is dispersed with stirring the rubbing agent for uniformly, adding selected parts by weight, stirs
Mix and be uniformly dispersed；
4) continue stirring in the case where vacuum condition is 0.08-0.12MPa and lotion is made, sterile filling produces.
The rodent toothpaste of embodiment 5
Rodent is included with toothpaste described in the present embodiment：By weight, total number 1000, wherein rubbing agent
210 parts, 250 parts of NMF, 5 parts of flavouring agent, 30 parts of foaming agent, 20 parts of thickener, function intensified 20 parts of composition, 3 parts of stabilizer,
Surplus is deionized water.
Wherein, the rubbing agent is from chick bone powder and calcium phosphate dibasic dihydrate and the mixture of cellulose, wherein chick bone powder
Content is 60%, and calcium phosphate dibasic dihydrate content is 15%, cellulose 25%；The NMF selects glycerine；The flavouring agent
From vanilla flavored flavouring agent；The foaming agent selects APG；The thickener selects xanthans；Stabilizer selects pyrophosphoric acid
Four sodium；The functional chemical conversion point includes active ingredient of Chinese herbs and ferment, ratio 1：1, wherein active Chinese drug component point includes：Honeybee
3 parts of glue, 3 parts of Caulis Perillae, windproof 0.5 part, 0.5 part of wild pepper, 0.25 part of notopterygium root, 0.25 part of asarum, 1.5 parts of radix scutellariae, Chinese gall 1
Part, the ferment is 1.5 parts of protease, 1.5 parts of lipase, 1.5 parts of cellulase, 1.5 parts of amylase, 1 part of lysozyme, newborn mistake
1 part of oxide enzyme, 1 part of glucose oxidase, more than 0.5 part of superoxide dismutase, 0.5 part of oxidoreducing enzyme；Surplus is deionization
Water.
This toothpaste can effectively pure and fresh rodent implication, vanilla flavored is highly susceptible to being received by rodent, can effectively press down
Main cariogenic bacteria is made and killed, has inhibitory action to bacterial plaque forming process, and the activity of rodent oral cavity flora can be adjusted.
The rodent of embodiment 6 toothpaste preparation method
The present embodiment provides a kind of preparation method of the toothpaste of rodent as described in Example 5, and its step is as follows：
1) foaming agent, active ingredient of Chinese herbs are mixed with NMF, high-speed stirred, be prepared as molten according to selected parts by weight
Liquid or suspension, obtain mixture A3；
2) ferment is dissolved in the water according to selected parts by weight example, and mixed with thickener and flavouring agent, mixed
Thing B3；
3) the mixture B3 is added in mixture A3, is dispersed with stirring the rubbing agent for uniformly, adding selected parts by weight, stirs
Mix and be uniformly dispersed；
4) continue stirring in the case where vacuum condition is 0.08-0.12MPa and lotion is made, sterile filling produces.
Although above the present invention is made to retouch in detail with general explanation, embodiment and experiment
State, but on the basis of the present invention, it can be made some modifications or improvements, this is apparent to those skilled in the art
's.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, are belonged to claimed
Scope.
Claims (10)
- A kind of 1. pet toothpaste, it is characterised in that：By weight, including following component：Rubbing agent 80-600 parts, NMF 50-300 parts, flavouring agent 0-10 parts, foaming agent 10-50 parts, thickener 5-30 parts, function intensified composition 4-20 parts, stabilizer 1-6 Part, wherein, the function intensified composition is the mixture of active ingredient of Chinese herbs and ferment.
- 2. pet toothpaste according to claim 1, it is characterised in that：The pet dentifrice total weight parts are 1000 parts, Surplus is deionized water.
- 3. pet toothpaste according to claim 1 or 2, it is characterised in that：In the function intensified composition, active Chinese drug component The weight of composition and ferment ratio is 1:5-5:1, it is preferably in a proportion of 1:1.
- A kind of 4. pet toothpaste according to claim any one of 1-3, it is characterised in that：The active ingredient of Chinese herbs bag Include：Propolis, Caulis Perillae；Preferably, in addition at least one of windproof, wild pepper, notopterygium root, asarum, radix scutellariae, Chinese gall；It is furthermore preferred that the composition includes propolis 2.5-3 parts, Caulis Perillae 2.5-3 parts, windproof 0.1-0.5 parts, wild pepper 0.1-0.5 Part, notopterygium root 0.1-0.3 parts, asarum 0.1-0.3 parts, radix scutellariae 0.5-2 parts, Chinese gall 0.1-1 parts.
- A kind of 5. pet toothpaste according to claim any one of 1-4, it is characterised in that：The ferment be protease, Lipase, cellulase, amylase, lysozyme, lactoperoxidase, glucose oxidase, more than superoxide dismutase, oxidation also One or more in protoenzyme.
- 6. pet toothpaste according to claim 5, it is characterised in that：The ferment includes：Protease 1-3 parts, fat Enzyme 0.5-3 parts, cellulase 0-2 parts, amylase 0.5-3 parts, lysozyme 0.5-1 parts, lactoperoxidase 0.5-1 parts, glucose Oxidizing ferment 0-1 parts, more than superoxide dismutase 0.5-1 parts, oxidoreducing enzyme 0.5-1 parts.
- 7. according to the pet toothpaste described in claim any one of 1-6, it is characterised in that the rubbing agent includes bone meal, fine Two or three among dimension element and calcium phosphate dibasic dihydrate, it is preferred that the content of bone meal is the 15%- of rubbing agent total amount 75%, and/or, content of cellulose is the 10-25% of rubbing agent total amount, and/or, calcium phosphate dibasic dihydrate content is that rubbing agent is total The 5-15% of amount.
- 8. pet toothpaste according to claim 7, it is characterised in that：The NMF is from D-sorbite, glycerine, third One or more in glycol, polyethylene glycol, polyalcohol, and/or, the foaming agent selects APG or Hamposyl L Sodium, and/or, the thickener selects the mixture of one or both of natural plant, xanthans, carragheen, agar.
- A kind of 9. pet toothpaste, it is characterised in that：In parts by weight, total weight parts are 1000 parts, and formula is as follows：Bone meal 120-147 parts, calcium phosphate dibasic dihydrate 30-40 parts, cellulose 30-55 parts, glycerine 200-300 parts, flavouring agent 5 Part, foaming agent 25-35 parts, xanthans 15-25 parts, active ingredient of Chinese herbs 8-10 parts, ferment 5-10 parts, 3 parts of tetrasodium pyrophosphate are remaining Measure as deionized water；The active ingredient of Chinese herbs includes：Propolis 2.5-3 parts, Caulis Perillae 2.5-3 parts, windproof 0.5 part, 0.5 part of wild pepper, notopterygium root 0.2-0.3 parts, asarum 0.2-0.3 parts, radix scutellariae 1-1.5 parts, Chinese gall 0.6-1 parts,The ferment includes：Protease 1-3 parts, lipase 1-2.5 parts, amylase 0.5-2.5 parts, lysozyme 0.5-1 parts, newborn mistake Oxide enzyme 0.5-1 parts, more than superoxide dismutase 0.5-1 parts, 0.5 part of oxidoreducing enzyme, glucose oxidase 0-1 parts, fiber Plain enzyme 0-2 parts.
- A kind of 10. method for preparing the pet toothpaste as described in claim any one of 1-9, it is characterised in that：Including as follows Step：1) foaming agent, active ingredient of Chinese herbs are mixed with NMF, high-speed stirred, is prepared as solution or suspension, is mixed Thing A；2) ferment is dissolved in the water, and mixed with thickener and flavouring agent, obtain mixture B；3) the mixture B is added in mixture A, is dispersed with stirring uniformly, adds rubbing agent, be dispersed with stirring uniformly；4) continue stirring under vacuum and lotion is made, sterile filling produces.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108888558A (en) * | 2018-08-08 | 2018-11-27 | 广州立白企业集团有限公司 | A kind of Pet tooth-cleaning gel and preparation method thereof |
| CN109730207A (en) * | 2019-03-18 | 2019-05-10 | 南京欧贝威生物技术有限公司 | A kind of dog cat oral care nutritive cream |
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|---|---|---|---|---|
| EP0509930A1 (en) * | 1991-04-17 | 1992-10-21 | Laboratoires Veterinaires Cany's | Hygiene compositions for domestic animals |
| CN103876983A (en) * | 2014-03-22 | 2014-06-25 | 南通蛇类治疗研究所 | Ferment enzyme toothpaste |
| CN104666106A (en) * | 2013-11-29 | 2015-06-03 | 青岛根源生物技术集团有限公司 | Preparation process of biological enzyme toothpaste |
| CN106606439A (en) * | 2015-10-20 | 2017-05-03 | 青岛益邦瑞达生物科技有限公司 | Toothpaste composition |
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- 2017-08-09 CN CN201710675356.9A patent/CN107441019B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0509930A1 (en) * | 1991-04-17 | 1992-10-21 | Laboratoires Veterinaires Cany's | Hygiene compositions for domestic animals |
| CN104666106A (en) * | 2013-11-29 | 2015-06-03 | 青岛根源生物技术集团有限公司 | Preparation process of biological enzyme toothpaste |
| CN103876983A (en) * | 2014-03-22 | 2014-06-25 | 南通蛇类治疗研究所 | Ferment enzyme toothpaste |
| CN106606439A (en) * | 2015-10-20 | 2017-05-03 | 青岛益邦瑞达生物科技有限公司 | Toothpaste composition |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108888558A (en) * | 2018-08-08 | 2018-11-27 | 广州立白企业集团有限公司 | A kind of Pet tooth-cleaning gel and preparation method thereof |
| CN109730207A (en) * | 2019-03-18 | 2019-05-10 | 南京欧贝威生物技术有限公司 | A kind of dog cat oral care nutritive cream |
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| CN107441019B (en) | 2020-06-09 |
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