CN107432472A - A kind of composition for treating diarrhoea and its application - Google Patents
A kind of composition for treating diarrhoea and its application Download PDFInfo
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- CN107432472A CN107432472A CN201710743148.8A CN201710743148A CN107432472A CN 107432472 A CN107432472 A CN 107432472A CN 201710743148 A CN201710743148 A CN 201710743148A CN 107432472 A CN107432472 A CN 107432472A
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- poria cocos
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Classifications
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Abstract
The present invention relates to functional food or health food, specifically discloses a kind of composition for treating diarrhoea and its application.The composition includes the component of following parts by weight：5 20 parts of ginseng, 5 20 parts of Gorgon fruit, 5 15 parts of Poria cocos, 20 30 parts of Chinese yam, 5 10 parts of Semen Lablab Album, fry 5 10 parts of lotus seeds, 10 20 parts of coix seed, 5 10 parts of fructus amomi, 5 10 parts of balloonflower root, 5 10 parts of radix glycyrrhizae.The present invention is by the component cooperate with shared, and by adjusting gastrointestinal function, tonifying spleen nourishing the stomach, dehumidifying antidiarrheal have the function that treatment diarrhoea, be applicable to irregular diet, quick dining and eat outside it is unhygienic caused by there is the crowd of diarrhoea problem.Granule provided by the invention is easy to carry, takes that quick, mouthfeel is moderate, and has distinctive fragrance.The composition of the present invention has the characteristics that to take that the cycle is short, curative effect is good, has no side effect in applied to treatment diarrhea disease compared to the medicine of the treatment diarrhoea of routine.
Description
Technical field
The present invention relates to functional food or health food, specifically, is related to a kind of composition for treating diarrhoea and its answers
With.
Background technology
Diarrhoea is commonly called as " suffering from diarrhea ", refers to defecation frequency significantly more than the frequency being accustomed on ordinary days, excrement matter is thin, and moisture increases
Add.The etiology and pathogenesis of diarrhoea is more complicated, theory of traditional Chinese medical science think " damp and hot heresy, disorder of the spleen and stomach caused by internal damage, cause the dysfunction of the spleen in transport, stomach lose treatment for relieving indigestion and constipation,
More hold under the arm stagnant " it is the main reason for diarrhoea.With the acceleration of modern life rhythm, diet is irregular, quick dining and outer
The problems such as eating a series of unhygienic caused taste imbalances, indigestion, enterogastritis, diarrhoea is increasingly severe.Doctor trained in Western medicine frequently with
The antibiotics such as Ofloxacin, Norfloxacin treatment diarrhoea, but as antibiotic is abused, the problems such as producing drug resistance,
It is not only invalid, also many side effects.In addition to the toxic side effect of antibiotic in itself, internal microecological balance can be also destroyed, is caused
Flora Disturbance, make diarrhoea protracted course of disease, or secondary suprainfection on the contrary.For doctor trained in Western medicine, Chinese herbal treatment have it is integrally-regulated,
The advantages of diagnosis and treatment based on an overall analysis of the illness and the patient's condition, have no toxic side effect more safe and effective.
Ginseng is sweet, slight bitter, warm-natured, flat.Returns spleen, lung channel, the heart channel of Hang-Shaoyin.With reinforcing vital energy, veins takes off admittedly, reinforce the spleen to benefit the lung,
Promote the production of body fluid, the effect of calming the nerves.Gorgon fruit is sweet, puckery, flat.Returns spleen, kidney channel.With supplementing the kidney to control the nocturnal, tonifying spleen and stopping diarrhea, the effect of eliminating dampness and arresting leucorrhea.
Poria cocos is sweet, light, puts down.The thoughts of returning home, lung, spleen, kidney channel.With clearing damp and promoting diuresis, invigorating the spleen, the effect of calming heart.It is usually used in oedema oliguria, phlegm and retained fluid
Feel dizzy and heart palpitations, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.Chinese yam is sweet, puts down.Returns spleen, lung, kidney channel.With tonifying spleen nourishing the stomach,
Engender liquid and benefic lung, the puckery essence of kidney tonifying.For spleen eating less, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, and under band, frequent micturition, abnormal heat is quenched one's thirst.
Semen Lablab Album is sweet, tepor.Returns spleen, stomach.For weakness of the spleen and the stomach, poor appetite, diarrhea, leukorrhea, summer-heat and damp is vomited and diarrhoea, uncomfortable in chest
Abdominal distension.Semen Lablab Album invigorating the spleen for eliminating dampness is fried, is usually used in splenasthenic diarrhea.The Chinese medicines such as lotus seeds, coix seed, fructus amomi, balloonflower root and radix glycyrrhizae are fried to match somebody with somebody
There is the effect of regulation gastrointestinal function, tonifying spleen nourishing the stomach, dehumidifying antidiarrheal 5 more.
The content of the invention
In order to solve problems of the prior art, it is an object of the invention to provide a kind of composition for treating diarrhoea and
It is applied.
In order to realize the object of the invention, technical scheme is as follows：
Present invention firstly provides a kind of composition for treating diarrhoea, the component of following parts by weight is included：Ginseng 5-20 parts, Gorgon euryale
Real 5-20 parts, Poria cocos 5-15 parts, Chinese yam 20-30 parts, Semen Lablab Album 5-10 parts, fry lotus seeds 5-10 parts, coix seed 10-20 parts, fructus amomi
5-10 parts, balloonflower root 5-10 parts, radix glycyrrhizae 5-10 parts.
Preferably, the composition includes the component of following parts by weight：Ginseng 5-15 parts, Gorgon fruit 5-15 parts, Poria cocos 5-10
Part, Chinese yam 20-25 parts, Semen Lablab Album 5-8 parts, fry lotus seeds 5-9 parts, coix seed 10-15 parts, fructus amomi 5-7 parts, balloonflower root 5-8 parts, radix glycyrrhizae
5-8 parts.
It is further preferable that the composition includes the component of following parts by weight：15 parts of ginseng, 15 parts of Gorgon fruit, 12 parts of Poria cocos,
23 parts of Chinese yam, 7 parts of Semen Lablab Album, fry 9 parts of lotus seeds, 15 parts of coix seed, 6 parts of fructus amomi, 7 parts of balloonflower root, 6 parts of radix glycyrrhizae.
In above-mentioned composition：
The parts by weight can be unit of weight known to the field of medicaments such as μ g, mg, g, kg or its multiple, such as
1/10th, 1/100,10 times, 100 times etc..
Present invention also offers foregoing to prepare the application in treating diarrhoea functional food or health food.
The functional food or health food can be medicines and health protection field regular dosage form, such as granule, tablet, capsule, cream
Taste, beverage etc..
Optional/preferably, the formulation is granule, includes the component of following parts by weight：Ginseng 5-20 parts, Gorgon fruit 5-20
Part, Poria cocos 5-15 parts, Chinese yam 20-30 parts, Semen Lablab Album 5-10 parts, stir-fry lotus seeds 5-10 parts, coix seed 10-20 parts, fructus amomi 5-10 parts,
Balloonflower root 5-10 parts, radix glycyrrhizae 5-10 parts, prebiotics 50-100 parts, (dosage is other components gross weight to binding agent 2%-10%
2%-10%).
Preferably, the granule includes the component of following parts by weight：Ginseng 5-15 parts, Gorgon fruit 5-15 parts, Poria cocos 5-10
Part, Chinese yam 20-25 parts, Semen Lablab Album 5-8 parts, fry lotus seeds 5-9 parts, coix seed 10-15 parts, fructus amomi 5-7 parts, balloonflower root 5-8 parts, radix glycyrrhizae
5-8 parts, prebiotics 50-80 parts, binding agent 2%-8% (dosage is the 2%-8% of other components gross weight).
It is further preferable that the granule includes the component of following parts by weight：15 parts of ginseng, 15 parts of Gorgon fruit, 12 parts of Poria cocos,
23 parts of Chinese yam, 7 parts of Semen Lablab Album, 9 parts of lotus seeds are fried, 15 parts of coix seed, 6 parts of fructus amomi, 7 parts of balloonflower root, 6 parts of radix glycyrrhizae, 60 parts of prebiotics, are glued
Tie agent 5% (dosage is the 5% of other components gross weight).
Wherein, the prebiotics is oligoisomaltose, FOS or xylo-oligosaccharide.In the specific embodiment party of the present invention
In formula, the prebiotics is oligoisomaltose, purchased from Tianjin Yi Beiyuan natural products Technology Co., Ltd., its oligomeric different malt
Sugared content is more than 80%.
Wherein, the binding agent is the alcohol of 80% (volume fraction).
The present invention further provides the preparation method of the granule：
1) oligoisomaltose is sieved, chooses fine powder under 60 mesh sieves, ginseng pulverate, gorgon euryale seed powder, Poria cocos are weighed according to proportioning
Powder, yam flour, Semen Lablab Album powder, stir-fry lotus nut starch, coix seed powder, amomum powder, balloonflower powder, licorice powder, oligoisomaltose fine powder, are mixed
Close uniform；
2) it is adhesive by the alcohol of the fine powder mixed addition 80%, the particle of 60 mesh is made, is 50 DEG C in temperature
Under the conditions of be dried, 60 minutes drying times, packing, produce.
Alternatively, the formulation can be granule.During preparation, the extract using the composition may be selected.The present invention
The ginseng, Gorgon fruit, Poria cocos, Chinese yam, Semen Lablab Album, stir-fry lotus seeds, coix seed, fructus amomi, balloonflower root and radix glycyrrhizae, can be normal by prior art
Rule method prepares extract, also commercially available to buy extract.
The present invention relates to raw material or reagent be ordinary commercial products, the operation being related to is unless otherwise specified
This area routine operation.
On the basis of common sense in the field is met, above-mentioned each optimum condition, it can be mutually combined, obtain specific embodiment party
Formula.
The beneficial effects of the present invention are：
1st, the present invention is based on ginseng, Gorgon fruit, Poria cocos, Chinese yam, Semen Lablab Album, stir-fry lotus seeds, coix seed, fructus amomi, balloonflower root, radix glycyrrhizae
Want raw material, make various composition reasonable formula, cooperate with shared, by adjust gastrointestinal function, tonifying spleen nourishing the stomach, dehumidifying antidiarrheal reach treatment
The effect of diarrhoea, be applicable to irregular diet, quick dining and eat outside it is unhygienic caused by there is the people of diarrhoea problem
Group.
2nd, granule provided by the invention is easy to carry, takes that quick, mouthfeel is moderate, and has distinctive fragrance.
3rd, by experiment, find to take the volunteer of composition and granule provided by the invention, diarrhoea situation obtains bright
It is aobvious to improve.
The medicine for the treatment of diarrhoea of the composition of the present invention in applied to treatment diarrhea disease compared to routine has clothes
With the cycle is short, curative effect is good, have no side effect the features such as.
Embodiment
The preferred embodiment of the present invention is described in detail below in conjunction with embodiment.It is it will be appreciated that following real
Providing merely to play the purpose of explanation for example is applied, is not used to limit the scope of the present invention.The skill of this area
Art personnel can carry out various modifications and replacement in the case of without departing substantially from spirit of the invention and spirit to the present invention.
Material used, reagent etc., unless otherwise specified, are commercially obtained in following embodiments.
In granule preparation process, unless otherwise specified, used means are this area conventional technology.
The ginseng is less than 5 years ginseng raw powder of plantation, purchased from Tianjin Yi Beiyuan natural products Technology Co., Ltd.；
The Semen euryales extract is 10：1 ratio extract, purchased from Tianjin Yi Beiyuan natural products Technology Co., Ltd.；
Pachymaran content is 30-50% in the tuckahoe extracts, and triterpene acid content is 0.5-2%, purchased from Tianjin benefit
Bei Yuan natural products Technology Co., Ltd.；
Dioscin content is 5-20% in the yam extract, purchased from Tianjin benefit first limited public affairs of natural products technology again
Department；
The Semen Lablab Album extract is 10：1 ratio extract, purchased from Tianjin Yi Beiyuan natural products Technology Co., Ltd.；
The stir-fry Semen Nelumbinis extract is 10：1 ratio extract, purchased from Tianjin Yi Beiyuan natural products Technology Co., Ltd.；
The Semen Coicis extract is 10：1 ratio extract, purchased from Tianjin Yi Beiyuan natural products Technology Co., Ltd.；
The Fructus Amomi extract is 10：1 ratio extract, purchased from Tianjin Yi Beiyuan natural products Technology Co., Ltd.；
The Radix Platycodonis extract is 10：1 ratio extract, purchased from Tianjin Yi Beiyuan natural products Technology Co., Ltd.；
Glycyrrhizic acid content is 2-5%, flavones content 2-5% in the licorice, and purchased from Tianjin benefit, member is natural again
Product Technology Co., Ltd.；
The oligoisomaltose content is more than 80%, purchased from Tianjin Yi Beiyuan natural products Technology Co., Ltd..
Embodiment 1
Parts by weights also known as takes 15 parts of dry ginseng pulverate, 15 parts of gorgon euryale seed powder, 12 parts of Poria cocos powder, 23 parts of yam flour, white flat
7 parts of bean powder, fry 9 parts of lotus nut starch, 15 parts of coix seed powder, 6 parts of amomum powder, 7 parts of balloonflower powder, 6 parts of licorice powder, oligoisomaltose powder
60 parts, Sucralose 0.2%, it is well mixed, sprays binding agent 5%.The particle of 60 mesh is made, under conditions of temperature is 50 DEG C
It is dried, 60 minutes drying times, dispenses.
Embodiment 2
Parts by weights also known as takes 10 parts of dry ginseng pulverate, 10 parts of Gorgon fruit, 10 parts of Poria cocos, 30 parts of Chinese yam, 5 parts of Semen Lablab Album,
7 parts of lotus seeds are fried, bran fries 13 parts of coix seed, and 8 parts of fructus amomi, 7 parts of balloonflower root, 10 parts of radix glycyrrhizae, 60 parts of oligoisomaltose powder, mixing is
It is even, spray binding agent 5%.Sucralose 0.2%, the particle of 60 mesh is made, is dried, does under conditions of being 50 DEG C in temperature
Dry 60 minutes time, packing.
Embodiment 3
Parts by weights also known as takes 5 parts of dry ginseng pulverate, 5 parts of Gorgon fruit, 5 parts of Poria cocos, 20 parts of Chinese yam, 5 parts of Semen Lablab Album, fries lotus
10 parts of son, bran fry 20 parts of coix seed, 10 parts of fructus amomi, 15 parts of balloonflower root, 10 parts of radix glycyrrhizae, 60 parts of oligoisomaltose powder, Sucralose
0.2%, it is well mixed, sprays binding agent 5%.The particle of 60 mesh is made, is dried, dries under conditions of being 50 DEG C in temperature
60 minutes time, packing.
Embodiment 4
Parts by weights also known as takes 7 parts of dry ginseng pulverate, 7 parts of Gorgon fruit, 13 parts of Poria cocos, 25 parts of Chinese yam, 5 parts of Semen Lablab Album, fries
9 parts of lotus seeds, bran fry 10 parts of coix seed, 9 parts of fructus amomi, 14 parts of balloonflower root, 8 parts of radix glycyrrhizae, 60 parts of oligoisomaltose powder, Sucralose
0.2%, it is well mixed, sprays binding agent 5%.The particle of 60 mesh is made, is dried, dries under conditions of being 50 DEG C in temperature
60 minutes time, packing.
Embodiment 5
Parts by weights also known as takes 15 parts of dry ginseng pulverate, 15 parts of Semen euryales extract, 12 parts of tuckahoe extracts, Chinese yam extraction
23 parts of thing, 7 parts of Semen Lablab Album extract, 9 parts of Semen Nelumbinis extract is fried, 15 parts of Semen Coicis extract, 6 parts of Fructus Amomi extract, balloonflower root carries
Take 7 parts of thing, 6 parts of licorice, 60 parts of oligoisomaltose powder, 20 parts of microcrystalline cellulose, 5 parts of CMS, stearic acid
Magnesium 1%, it is well mixed, direct pressed powder.
Experimental example 1
Prove that this composition has the experiment for the treatment of diarrhoea
1st, crowd selects：Choose 25~45 years old diarrhea patient, each 60 people of men and women.
2nd, experiment packet：120 volunteers are divided into 6 groups, and this 6 groups of volunteers take the group in embodiment 1-4 respectively
Medicine in compound and comparative example 1,2.Comparative example 1 by operation instructions takes benzene, and piperidines (treats acute and chronic feature abdomen
Rush down), one at a time, 3 times a day.Comparative example 2 takes Norfloxacin (being suffered from diarrhoea caused by treatment bacterium infection) by operation instructions,
One time 4,2 times a day.
3rd, experimental method：The volunteer for taking embodiment 1-4 takes according to dosage, and daily 3 eat one after each meal once, every time
5g warm water takes, and continuously takes 7 days.The volunteer for taking comparative example 1,2 takes to specifications, continuously takes 7 days.
4th, experimental result see the table below：
| Example is cured completely | Significantly cure example | Substantially invalid example | |
| Embodiment 1 | 16 | 2 | 2 |
| Embodiment 2 | 14 | 3 | 3 |
| Embodiment 3 | 11 | 6 | 3 |
| Embodiment 4 | 13 | 3 | 4 |
| Comparative example 1 | 9 | 6 | 5 |
| Comparative example 2 | 7 | 7 | 6 |
Can be drawn from the healing result in table, the effect of embodiments of the invention 1-4 treatment diarrhoea it is significant better than pair
Ratio 1 and comparative example 2.Illustrating the composition of the present invention has the function that treatment diarrhoea, and for acute and chronic functional diarrhea
With bacterium infection caused by suffer from diarrhoea and have positive effect.Suffering from comparative example 1,2 does not occur in the patient for taking embodiment 1-4 simultaneously
Abdominal discomfort that person occurs, nausea and vomiting, the dizzy side effect such as drowsiness.Illustrate that the composition of the present invention safely and effectively, without pair is made
With.
Although above the present invention is described in detail with a general description of the specific embodiments,
On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause
This, these modifications or improvements, belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (10)
1. a kind of composition for treating diarrhoea, it is characterised in that the composition includes the component of following parts by weight：Ginseng 5-20
Part, Gorgon fruit 5-20 parts, Poria cocos 5-15 parts, Chinese yam 20-30 parts, Semen Lablab Album 5-10 parts, stir-fry lotus seeds 5-10 parts, coix seed 10-20 parts,
Fructus amomi 5-10 parts, balloonflower root 5-10 parts, radix glycyrrhizae 5-10 parts.
2. composition according to claim 1, it is characterised in that the composition includes the component of following parts by weight：People
Join 5-15 parts, Gorgon fruit 5-15 parts, Poria cocos 5-10 parts, Chinese yam 20-25 parts, Semen Lablab Album 5-8 parts, fry lotus seeds 5-9 parts, coix seed 10-
15 parts, fructus amomi 5-7 parts, balloonflower root 5-8 parts, radix glycyrrhizae 5-8 parts.
3. composition according to claim 2, it is characterised in that the composition includes the component of following parts by weight：People
15 parts of ginseng, 15 parts of Gorgon fruit, 12 parts of Poria cocos, 23 parts of Chinese yam, 7 parts of Semen Lablab Album, fry 9 parts of lotus seeds, 15 parts of coix seed, 6 parts of fructus amomi, balloonflower root
7 parts, 6 parts of radix glycyrrhizae.
4. any one of claims 1 to 3 composition is preparing the application in treating diarrhoea functional food or health food.
A kind of 5. pharmaceutical preparation for treating diarrhoea, it is characterised in that containing any one of claims 1 to 3 composition or by
Any one of claims 1 to 3 composition is prepared.
6. preparation according to claim 5, it is characterised in that the preparation is granule.
7. preparation according to claim 6, it is characterised in that the raw material of the granule includes the group of following parts by weight
Point：Ginseng 5-20 parts, Gorgon fruit 5-20 parts, Poria cocos 5-15 parts, Chinese yam 20-30 parts, Semen Lablab Album 5-10 parts, fry lotus seeds 5-10 parts, the heart of a lotus seed
Seed of jog's tears 10-20 parts, fructus amomi 5-10 parts, balloonflower root 5-10 parts, radix glycyrrhizae 5-10 parts, prebiotics 50-100 parts；And weight is foregoing group
Divide gross weight 2%-10% binding agent.
8. preparation according to claim 7, it is characterised in that the raw material of the granule includes the group of following parts by weight
Point：Ginseng 5-15 parts, Gorgon fruit 5-15 parts, Poria cocos 5-10 parts, Chinese yam 20-25 parts, Semen Lablab Album 5-8 parts, fry lotus seeds 5-9 parts, Job's tears
Benevolence 10-15 parts, fructus amomi 5-7 parts, balloonflower root 5-8 parts, radix glycyrrhizae 5-8 parts, prebiotics 50-80 parts；And weight is aforementioned component gross weight
Measure 2%-8% binding agent.
9. preparation according to claim 8, it is characterised in that the raw material of the granule includes the group of following parts by weight
Point：15 parts of ginseng, 15 parts of Gorgon fruit, 12 parts of Poria cocos, 23 parts of Chinese yam, 7 parts of Semen Lablab Album, fry 9 parts of lotus seeds, 15 parts of coix seed, fructus amomi 6
Part, 7 parts of balloonflower root, 6 parts of radix glycyrrhizae, 60 parts of prebiotics；And the binding agent that weight is aforementioned component gross weight 5%.
10. the preparation described in any one of claim 6~9, it is characterised in that its preparation method comprises the following steps：
1) prebiotics is sieved, choose 60 mesh sieves under fine powder, according to proportioning weigh ginseng pulverate, gorgon euryale seed powder, Poria cocos powder, yam flour,
Semen Lablab Album powder, lotus nut starch, coix seed powder, amomum powder, balloonflower powder, licorice powder, oligoisomaltose fine powder are fried, be well mixed；
2) fine powder mixed is added into adhesive, the particle of 60 mesh is made, be dried, do under conditions of being 50 DEG C in temperature
The dry 60 minutes time, packing, produce.
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| CN107432472B (en) | 2020-12-01 |
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Denomination of invention: A composition for treating diarrhea and its application Effective date of registration: 20231009 Granted publication date: 20201201 Pledgee: China Construction Bank Corporation Tianjin Development Branch Pledgor: TIANJIN KANGSHI BIOTECHNOLOGY Co.,Ltd. Registration number: Y2023980059989 |