CN107412661A - A kind of Chinese medicine composition for treating impotence, premature ejaculation and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating impotence, premature ejaculation and preparation method thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/64—Orobanchaceae (Broom-rape family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention discloses a kind of Chinese medicine composition for treating impotence, premature ejaculation and preparation method thereof.The Chinese medicine composition is raw material by Semen Cuscutae, barrenwort, prepared rhizome of rehmannia, fructus amomi, the fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, Paper mulberry Fruit, the fruit of Cherokee rose, fructus alpiniae oxyphyllae, semen allii tuberosi, raspberry, saline cistanche, it is prepared by certain weight, it can be prepared into any conventional oral formulations.This product has the effect of nourishing liver and kidney, benefiting male body essence and invigorating sex functions.Clinically it is used to treat impotence, premature ejaculation, it is evident in efficacy, any adverse reaction is not found.
Description
Technical field
The present invention is to be related to a kind of Chinese medicine composition, specifically, is related to a kind of Chinese medicine composition for treating impotence, premature ejaculation
And preparation method thereof.
Background technology
Impotence refers to male in sexual life, penis anorthosis or erect it is not hard or hard and soon, it is impossible to complete normal
Sexual life, or penis can not insert vagina and have sexual intercourse at all, and impotence is also known as " impotence " etc., is most common man's property work(
Energy obstacle disease, once in a while 1-2 sexual intercourse fail, it is impossible to think exactly to have suffered from impotence.Only in sexual intercourse mortality more than 25%
Shi Caineng is diagnosed as impotence, is counted according to data from abroad, and impotence patient accounts for the 37%- of whole male sexual disfunctions
42%.Domestic relevant investigation shows that impotence occurs for the people that 10% is there are about in adult male.The incidence of impotence with the age increasing
Grow and rise.
After premature ejaculation refers to penis insertion vagina, not yet come to orgasm in women, and the sex time of male is shorter than 2 points
Clock, the sexual intercourse ejaculated and occurred ahead of time are discord obstacle, and general male 30% has this situation, though problem is small, making property is given birth to
Work it is of low quality, it is also possible to cause other sex dysfunctions such as impotence, consequence is serious, should draw attention and and early treatment.
At present, impotence drug therapy is mainly Sildenafil citrate tablets, premature ejaculation drug therapy be mainly serotonin again
Uptake inhibitor, what the country had listed is that hydrochloric acid Da Paxi stings, and they have certain toxic side effect, and price is somewhat expensive.
Therefore seek safely and effectively to treat impotence, premature ejaculation new Chinese medicine, it has also become vast impotence, Patients with Premature Ejaculation and doctor
Common aspiration.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating impotence, premature ejaculation.
The present invention also aims to provide a kind of Chinese medicine composition for treating impotence, premature ejaculation and preparation method thereof.
The scheme that the present invention solves is inventor, under the guidance of traditional Chinese medical theory, for impotence, the machine of premature ejaculation generation
Reason, for many years with reference to the clinical experience of oneself, is developed, this product has the effect of nourishing liver and kidney, benefiting male body essence and invigorating sex functions meticulously.Face
It is used to treat impotence, premature ejaculation on bed, it is evident in efficacy, any adverse reaction is not found.
The present invention is realized by following scheme, and medicine of the present invention is mainly the bulk drug system matched by following weight parts
Into：
Medicine of the present invention mainly each raw material preferred weight part proportioning be：
Medicine of the present invention mainly each raw material optimum weight part proportioning be：
30 parts of Semen Cuscutae, 25 parts of barrenwort, 30 parts of prepared rhizome of rehmannia, 15 parts of fructus amomi, 30 parts of the fruit of Chinese wolfberry, 15 parts of the fruit of Chinese magnoliavine, paper mulberry fruit
20 parts of son, 20 parts of the fruit of Cherokee rose, 15 parts of fructus alpiniae oxyphyllae, 20 parts of semen allii tuberosi, 20 parts of raspberry, 30 parts of saline cistanche
The preparation method of medicine of the present invention, its method and step are as follows：
(1) will formula described in Semen Cuscutae, barrenwort, prepared rhizome of rehmannia, fructus amomi, the fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, Paper mulberry Fruit, the fruit of Cherokee rose,
Fructus alpiniae oxyphyllae, semen allii tuberosi, raspberry, saline cistanche are ground into coarse powder, cross 20 mesh sieves, add the 8-15 times of ethanol measured immersion 12-24 hour；
(2) ultrasonic extraction 1-3 times, each 0.5-1 hours, collecting decoction, filtration, recovery ethanol is concentrated into is to density
The medicinal extract of 1.30~1.35 (60 DEG C), auxiliary material required when preparing different dosage forms, then the Chinese medicine preparation with routine can be added
Method is prepared into conventional peroral dosage form, such as capsule, granule, tablet.
Embodiment
Embodiment 1：A kind of capsule preparation method thereof for treating impotence, premature ejaculation of the present invention, its step are as follows：
30 parts of Semen Cuscutae, 25 parts of barrenwort, 30 parts of prepared rhizome of rehmannia, 15 parts of fructus amomi, 30 parts of the fruit of Chinese wolfberry, 15 parts of the fruit of Chinese magnoliavine, paper mulberry fruit
20 parts of son, 20 parts of the fruit of Cherokee rose, 15 parts of fructus alpiniae oxyphyllae, 20 parts of semen allii tuberosi, 20 parts of raspberry, 30 parts of saline cistanche
(1) will formula described in Semen Cuscutae, barrenwort, prepared rhizome of rehmannia, fructus amomi, the fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, Paper mulberry Fruit, the fruit of Cherokee rose,
Fructus alpiniae oxyphyllae, semen allii tuberosi, raspberry, saline cistanche are ground into coarse powder, cross 20 mesh sieves, add the ethanol of 15 times of amounts to soak 12 hours；
(2) ultrasonic extraction 2 times, 0.5 hour every time, collecting decoction, filtration, recovery ethanol be concentrated into density be 1.30~
The medicinal extract of 1.35 (60 DEG C), microcrystalline cellulose is added, mixed, dry, pulverize into fine powder, loaded capsule, produce capsule.
Embodiment 2：A kind of process for producing granula for treating impotence, premature ejaculation of the present invention, its step are as follows：
30 parts of Semen Cuscutae, 25 parts of barrenwort, 30 parts of prepared rhizome of rehmannia, 15 parts of fructus amomi, 30 parts of the fruit of Chinese wolfberry, 15 parts of the fruit of Chinese magnoliavine, paper mulberry fruit
20 parts of son, 20 parts of the fruit of Cherokee rose, 15 parts of fructus alpiniae oxyphyllae, 20 parts of semen allii tuberosi, 20 parts of raspberry, 30 parts of saline cistanche
(1) will formula described in Semen Cuscutae, barrenwort, prepared rhizome of rehmannia, fructus amomi, the fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, Paper mulberry Fruit, the fruit of Cherokee rose,
Fructus alpiniae oxyphyllae, semen allii tuberosi, raspberry, saline cistanche are ground into coarse powder, cross 20 mesh sieves, add the ethanol of 10 times of amounts to soak 24 hours；
(2) ultrasonic extraction 3 times, 1 hour every time, collecting decoction, filtration, recovery ethanol be concentrated into density be 1.30~
The medicinal extract of 1.35 (60 DEG C), dextrin, Steviosin, mixing are added, pelletized, dried, that is, granule is made.
Embodiment 3：A kind of method for preparing tablet thereof for treating impotence, premature ejaculation of the present invention, its step are as follows：
30 parts of Semen Cuscutae, 25 parts of barrenwort, 30 parts of prepared rhizome of rehmannia, 15 parts of fructus amomi, 30 parts of the fruit of Chinese wolfberry, 15 parts of the fruit of Chinese magnoliavine, paper mulberry fruit
20 parts of son, 20 parts of the fruit of Cherokee rose, 15 parts of fructus alpiniae oxyphyllae, 20 parts of semen allii tuberosi, 20 parts of raspberry, 30 parts of saline cistanche
(1) will formula described in Semen Cuscutae, barrenwort, prepared rhizome of rehmannia, fructus amomi, the fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, Paper mulberry Fruit, the fruit of Cherokee rose,
Fructus alpiniae oxyphyllae, semen allii tuberosi, raspberry, saline cistanche are ground into coarse powder, cross 20 mesh sieves, add the ethanol of 12 times of amounts to soak 24 hours；
(2) ultrasonic extraction 1 time, 1 hour every time, collecting decoction, filtration, recovery ethanol be concentrated into density be 1.30~
The medicinal extract of 1.35 (60 DEG C), adds microcrystalline cellulose, magnesium stearate, and mixing is made particle, tabletting, coating, produces tablet.
Experimental example
Chen, 29 years old, man.Often leave home to go on business, it is nervous when each return home is had sexual intercourse, and arrive and face room premature ejaculation.Such 3
Year, it is impossible to give birth to, be to cause Mr. and Mrs to become estranged, it is invalid once repeatedly to seek medical advice.Take the capsule of embodiment 1：Three times a day, three a time.Medication 3
After it, having sexual intercourse time first time maintains more than 20 minutes；After medication 20 days, abandon medicine and be cured.
Zhao, 38 years old, man.Impotence is more than 5 years.Penis anorthosis, with urethra burn feeling.Previously suffer from prostatitis.Through with
A large amount of kidney-nourishing yang-strengthening medicines are invalid, take the capsule of embodiment 1：Three times a day, three a time.After medication 5 days, telotism is hard and has
Power, continue 20 minutes, have sexual intercourse 2 times and succeed.
In above therapeutic process, patient has no any adverse reaction.
Although being above described in detail with a general description of the specific embodiments to the present invention,
On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause
This, these modifications or improvements, belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (4)
1. a kind of Chinese medicine composition for treating impotence, premature ejaculation, it is characterised in that it is mainly by the raw material of following weight
Medicine is made：
。
2. a kind of Chinese medicine composition for treating impotence, premature ejaculation according to claim 1, it is characterised in that it is mainly under
The bulk drug for arranging preferable weight is made：
。
A kind of 3. Chinese medicine composition for treating impotence, premature ejaculation according to claim 1,2, it is characterised in that it mainly by
The bulk drug of following optimum weight part proportioning is made：
30 parts of Semen Cuscutae, 25 parts of barrenwort, 30 parts of prepared rhizome of rehmannia, 15 parts of fructus amomi, 30 parts of the fruit of Chinese wolfberry, 15 parts of the fruit of Chinese magnoliavine, Paper mulberry Fruit 20
Part, 20 parts of the fruit of Cherokee rose, 15 parts of fructus alpiniae oxyphyllae, 20 parts of semen allii tuberosi, 20 parts of raspberry, 30 parts of saline cistanche.
4. the preparation method of a kind of impotence, premature ejaculation medicine according to claim 1 or 2 or 3, it is characterised in that under it includes
Row step：
(1) Semen Cuscutae, barrenwort, prepared rhizome of rehmannia, fructus amomi, the fruit of Chinese wolfberry, the fruit of Chinese magnoliavine, Paper mulberry Fruit, the fruit of Cherokee rose, intelligence development described in being formulated
Benevolence, semen allii tuberosi, raspberry, saline cistanche are ground into coarse powder, cross 20 mesh sieves, add the 8-15 times of ethanol measured immersion 12-24 hour；
(2) ultrasonic extraction 1-3 times, each 0.5-1 hours, collecting decoction, filtration, recovery ethanol be concentrated into density be 1.30~
The medicinal extract of 1.35 (60 DEG C), auxiliary material required when preparing different dosage forms, then the method for Chinese medicinal system with routine can be added
It is standby into conventional peroral dosage form, such as capsule, granule, tablet.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112546176A (en) * | 2020-12-30 | 2021-03-26 | 项二磊 | Traditional Chinese medicine pill for tonifying kidney and strengthening essence and preparation method thereof |
| CN115105574A (en) * | 2022-02-22 | 2022-09-27 | 合肥中威医药技术有限责任公司 | Traditional Chinese medicine composition for tonifying kidney and strengthening yang and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103251734A (en) * | 2013-05-21 | 2013-08-21 | 华夏先葆(北京)中药研究院有限公司 | Traditional Chinese medicine health-care preparation with cistanche and acanthopanax as main medicines |
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2017
- 2017-07-24 CN CN201710645466.0A patent/CN107412661A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251734A (en) * | 2013-05-21 | 2013-08-21 | 华夏先葆(北京)中药研究院有限公司 | Traditional Chinese medicine health-care preparation with cistanche and acanthopanax as main medicines |
Non-Patent Citations (2)
| Title |
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| 戚广崇: "《实用中医男科手册》", 30 June 1995, 知识出版社 * |
| 王君等: "《妙用枸杞治百病》", 31 March 2017, 中国科学技术出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112546176A (en) * | 2020-12-30 | 2021-03-26 | 项二磊 | Traditional Chinese medicine pill for tonifying kidney and strengthening essence and preparation method thereof |
| CN115105574A (en) * | 2022-02-22 | 2022-09-27 | 合肥中威医药技术有限责任公司 | Traditional Chinese medicine composition for tonifying kidney and strengthening yang and application thereof |
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Address after: 230031 6th Floor, Anhui Science and Technology Entrepreneurship Service Center, No. 8 Pihe Road, Shushan District, Hefei City, Anhui Province Applicant after: Hefei Haida Biopharmaceutical Technology Co., Ltd. Address before: Room 303, 3rd floor, Kechuang Center, No. 9 Daoxiang Road, Shushan District, Hefei City, Anhui Province Applicant before: Hefei Haida Biopharmaceutical Technology Co., Ltd. |
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| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171201 |