CN107412485A - 一种治疗老寒腿的中药外洗液 - Google Patents
一种治疗老寒腿的中药外洗液 Download PDFInfo
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Abstract
本发明公开了一种治疗老寒腿的中药外洗液,它由14味药材配制而成,比例为:当归60、防己30、千年健60、蓖麻根21、狗骨60、肉桂90、茜草6、牛膝25、甘草30、蜈蚣5、熟地黄6、地锦18、桂枝25、杜仲21。制备方法是将上述药材中肉桂、熟地黄和桂枝置于蒸汽夹层锅内,用95%乙醇电加热回流提取2小时,收集提取液备用,提取后的药渣与其他原料药混合水煮提取三次,时间分别为1.5小时、1小时、1小时,收集三次提取液混合均匀,将混匀后的提取液常压浓缩至相对密度为1.025(80℃热测)或1毫升药液相当于原料药1克;最后将乙醇提取液与水煮提取浓缩液混合均匀,静置24‑48小时,过滤,即得。
Description
技术领域
本发明属于中药技术领域,尤其涉及一种治疗老寒腿的中药外洗液。
背景技术
“老寒腿”医学全称是“下肢动脉硬化闭塞症”又称为“风湿性关节炎”。表现为当天阴下雨、气候转凉或受凉,髋、膝关节或双下肢冰凉、疼痛,但无关节红肿、畸形、功能异常及患肢触痛、温觉异常,实验室常规理化指标正常。“老寒腿”患者因劳累、寒凉刺激而复发或加重,常规治疗多采用消炎镇痛、抗风湿药物,如芬必得等,但长期服用易致胃炎、溃疡等病症。中药外洗可达到活血散寒、通络止痛的功效,无口服药物之弊,简单易行,事半功倍。
中医学对于老寒腿的治疗有丰富的经验。近年来人们开发了许多治疗老寒腿的中草药配方,如中国专利申请件201410405657.6号《专门用于老寒腿泡脚的中药配方》、201210535046.4号《一种治疗老寒腿的外洗中药组合物》、201310140010.0号《一种治疗老寒腿的中药》等。上述的种种治疗老寒腿的中草药配方均各不相同,治疗效果也不尽相同。但医生们仍然在开发新的药物,更好地为患者服务。
发明内容
本发明的目的就在于提供一种治疗老寒腿的中药外洗液配方,以增加治疗老寒腿的药物品种,使之能够为人们的健康服务。
本发明的另一个目的是提供该配方的制备方法。
本发明是基于对植物药的研究,优选出来的配方和制备工艺。
本发明的由14味药材配制而成,其质量配比为:
当归60、防己30、千年健60、蓖麻根21、狗骨60、肉桂90、茜草6、牛膝25、甘草30、蜈蚣5、熟地黄6、地锦18、桂枝25、杜仲21。
上述组方中:
当归为伞形科植物的根Angelica sinensis( Oliv.)Diels.味甘,温。有补血和血的功效。
防己为防己科植物粉防己的根Stephania tetrandra S.Moore.性味苦,寒。有行水,泻下焦湿热,治水肿臌胀,湿热脚气,手足挛痛的功效。
千年健Homalomena occulta(Lonur.)Schott.为天南星科植物千年健的根茎。性味辛,温。有祛风湿,壮筋骨,止痛。消肿。治风湿痹痛,肢节酸痛的功效。
蓖麻根为大戟植物蓖麻Ricinus communis L,性味淡,微温。有镇静解痉,祛风散瘀,治风湿疼痛的功效。
狗骨为犬科动物狗Canis familiaris L.的骨胳性味甘,温。健脾活络,活血生肌,治风湿痛,四肢麻木的功效。
肉桂Cinnamomum cassia Presl为樟科植物的干皮及枝皮。性味辛甘,热。有补元阳,暖脾胃,除积冷,通血脉的功效。
茜草为茜草科植物茜草Rubia cordifolia L的茎叶,根。性味苦,寒。有行血止血,通经活络,治风湿痹痛的功效。
牛膝Achyranthes bidentata BL为苋科植物牛膝的根,性味甘苦酸,平。有散瘀血,消痈肿,治腰膝骨痛的功效。
甘草Glycyrrhiza uralensis Fisch. 为豆科植物的根及根状茎。性味甘,平。有和中缓急,润肺。解毒,调和诸药的功效。
蜈蚣Scolopendra subspinipes mutilans L Koch。为大蜈蚣科动物少棘巨蜈蚣的干燥全虫。性味辛、温、有毒。有祛风,定惊,攻毒,散结的功效。
熟地黄Rechmannia jlutinosa(Gaertn)Libosch.为玄参科植物地黄的根茎。经加工炮制而成,药性由微寒转微温。有滋阴,养血除痹,通血脉的功效。
地锦为葡萄科植物爬山虎的根及茎Parthenocissus tricuspidata (Sieb.et Zuce.)Planceh.性味:甘、温。能活血,祛风,止痛。有活血,祛风,止痛的功效。
桂枝为樟科植物肉桂Cinnamomum cassia Presl的嫩枝。性味:辛甘,温。有发汗解肌,温经通脉,治风寒表证,风痹骨节挛痛的功效。
杜仲Eucommia ulmaidesOliv.为杜仲科植物杜仲的树皮。性味:甘薇辛,温。有补肝肾,强筋骨,治腰脊酸疼,足膝痿弱的功效。
本发明制备方法:称取肉桂、熟地黄和桂枝置于蒸汽夹层锅内,用95%乙醇电加热回流提取2小时,收集提取液备用,提取后的药渣与当归、防己、千年健、蓖麻根、狗骨、茜草、牛膝、甘草、蜈蚣、地锦和杜仲原料药混合水煮提取三次,时间分别为1.5小时、1小时、1小时,收集三次提取液混合均匀,将混匀后的提取液常压浓缩至相对密度为1.025(80℃热测)或1毫升药液相当于原料药1克;最后将乙醇提取液与水煮提取浓缩液混合均匀,静置24-48小时,过滤,即得。
本发明的使用方法将提取液用热水稀蚀20倍,浸泡双足(水温以能够耐受为度,以浸泡踝部为宜),每次浸泡20-30分钟,每日二次,8天为一个疗程。浸泡时可用手按摩足穴,泡后擦干,双足抬高,保暖。
本发明经临床试用,有效率为97%。典型的治愈病例有:
病例1;张某某,男 61岁,退伍军人。因患有老寒腿多年,膝关节经常感到酸麻疼痛,尤其在春季阴雨天多发。服用过治疗风湿关节炎的西药和中成药,始终不能治愈。后经过使用本发明一种治疗老寒腿的中药外洗液泡脚,8天后病情明显减轻,连续治疗3个 月后,酸麻疼痛消失,患者的老寒腿治愈,随访无复发.
病例2;陈某某,女,63岁,贵阳人。患有老寒腿 10 年了,膝关节部位经常感到酸麻疼痛。用过多种西药治疗,效果均不明显;后采用本发明药物治疗,10天见效,症状基本消失,连用16天后,疼痛消失,继续治疗3个月后,医院检查,恢复正常,病症痊愈。
病例3; 路某某,男,56岁,贵州省毕节市。患者3年前遇寒后,出现下肢关节疼痛,呈持续性酸胀痛,门诊以双膝痹症收治入院,采用药物、按摩、针灸等方法治疗,症状有好转,出院不久又复发。后来给予本发明治疗,2 个疗程后,症状明显减轻 ;继续治疗 3 个月后酸麻疼痛消失,疼痛消失后继续治疗一个月巩固治疗,随访无复发。
病例4;李某某、女、53岁,贵阳人。患者双膝、小腿肿胀、酸痛3年,在多家医院服用过治疗风湿关节炎的西药和中成药,始终不能治愈。后经过使用本发明治疗后病情明显减轻;连续治疗3个月痊愈。半年后随访,再未复发。
本发明一种治疗老寒腿的中药外洗液,具有滋补肝肾、补脾益气、补血活血、强筋健骨、逐瘀通经、通络止痛、祛寒除湿之功效。对于治疗“老寒腿”有显著疗效,总有效率为97%。在治疗过程中安全可靠,无口服药物之弊,使用方法简单,所用中药材易得,加工方便且成本低,适用于老寒腿患者的治疗。
具体实施方式
实施例 按照下列步骤制备治疗老寒腿的中药外洗液:
1、称取当归60g、防己30g、千年健60g、蓖麻根21g、狗骨60g、肉桂90g、茜草6g、牛膝25g、甘草30g、蜈蚣5g、熟地黄6g、地锦18g、桂枝25g、杜仲21g,备用。
2、 取肉桂、熟地黄和桂枝置于蒸汽夹层锅内,用95%乙醇电加热回流提取2小时,收集提取液备用。
3、 将上述乙醇提取后的药渣与其余各味原料药混合水煮提取三次,时间分别为1.5、1、1小时, 收集三次提取液混合均匀;
4、 将混匀后的提取液常压浓缩至相对密度为1.025(80℃热测)或1毫升药液相当于原料药1克;
5、将乙醇提取液与水煮提取浓缩液混合均匀,静置24-48小时,过滤,即得。
Claims (2)
1.一种治疗老寒腿的中药外洗液,其特征在于该中药组合物的质量配比为:
当归60、防己30、千年健60、蓖麻根21、狗骨60、肉桂90、茜草6、牛膝25、甘草30、蜈蚣5、熟地黄6、地锦18、桂枝25、杜仲21。
2. 根据权利要求1所述的一种治疗老寒腿的中药外洗液,其特征在于;制备方法是将上述肉桂、熟地黄和桂枝置于蒸汽夹层锅内,用95%乙醇电加热回流提取2小时,收集提取液备用,提取后的药渣与其他原料药混合水煮提取三次,时间分别为1.5小时、1小时、1小时,收集三次提取液混合均匀,将混匀后的提取液常压浓缩至相对密度为1.025(80℃热测)或1毫升药液相当于原料药1克;最后将乙醇提取液与水煮提取浓缩液混合均匀,静置24-48小时,过滤,即得成药。
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