CN1074121A - A kind of production method for the treatment of the coronary heart disease Chinese medicinal tablet - Google Patents
A kind of production method for the treatment of the coronary heart disease Chinese medicinal tablet Download PDFInfo
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- CN1074121A CN1074121A CN 92112338 CN92112338A CN1074121A CN 1074121 A CN1074121 A CN 1074121A CN 92112338 CN92112338 CN 92112338 CN 92112338 A CN92112338 A CN 92112338A CN 1074121 A CN1074121 A CN 1074121A
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Abstract
The present invention has set forth a kind of production method for the treatment of the Chinese medicinal tablet " GUANXIN DANSHEN PIAN " of coronary heart disease, and this tablet is made by Radix Notoginseng, Radix Salviae Miltiorrhizae, Lignum Dalbergiae Odoriferae oil medical material.Its way is that the Radix Salviae Miltiorrhizae percolation is produced thick paste, and with Radix Notoginseng powder mixing, goods are wrapped gum sugar sealing coat and sugarcoating layer.The tablet steady quality that makes with the method, do not get damp, never degenerate, evident in efficacy, be the good medicine for the treatment of coronary heart disease at present.
Description
The present invention relates to a kind of production method for the treatment of the coronary heart disease Chinese medicinal tablet.
Coronary heart disease is a big disease of harm humans health; according to relevant medical department statistics; coronary heart disease accounts for more than 3% at the sickness rate of China; American-European countries's sickness rate is higher; the people who got this disease is easy to cause angina pectoris or myocardial infarction; individual patient may cause serious arrhythmia or heart stopping collecting suddenly and cause sudden death, thus at present Chinese and western medicine all at the specific drug of constantly seeking treatment coronary heart disease.
The purpose of this invention is to provide a kind of production method of utilizing Chinese medicine to make the tablet that to treat coronary heart disease.
As everyone knows, there are many kinds of medical materials that the treatment heart disease is had significant curative effect in the Chinese medicine, as Radix Codonopsis, the Radix Astragali, Radix Salviae Miltiorrhizae, Radix Notoginseng, Radix Angelicae Sinensis, Fructus Schisandrae Chinensis, Lignum Dalbergiae Odoriferae wet goods, these medical materials are by the theory of the traditional Chinese medical science, and cloudy blood can nourish heart, benefiting vital QI for tranquillizing, to bring high blood pressure down, blood vessel dilating, increase blood circulation etc. and play great role, so the present invention chooses Radix Salviae Miltiorrhizae, Radix Notoginseng, the Lignum Dalbergiae Odoriferae oil primary raw material as the treatment medicaments for coronary disease.
Put down in writing on the medical book, Radix Salviae Miltiorrhizae has the effect of diastole peripheral vessel, can treat hypoplastic anemia, plays effects such as blood circulation promoting and blood stasis dispelling, tranquilizing the mind; Radix Notoginseng then can hemostasia and dissipation blood stasis, and subduing swelling and relieving pain has the blood coagulation time of shortening and makes the vasoconstriction effect; The function of Lignum Dalbergiae Odoriferae oil is the clots absorbing hemostasis, analgesic therapy.
The present invention utilizes the characteristic of these three kinds of medical materials by specific method just, produces treatment coronary heart disease is had Chinese medicinal tablet special effect and long keeping " GUANXIN DANSHEN PIAN ".
Pharmaceutical tablet method of the present invention is as follows:
1. medical material prescription (weight %):
Radix Notoginseng 40-55, Radix Salviae Miltiorrhizae 40-55, Lignum Dalbergiae Odoriferae oil 2-8
2. the Radix Salviae Miltiorrhizae thick paste produces
Exsiccant Radix Salviae Miltiorrhizae powder is broken into fine grained below 30 orders, add 5 liter of 90% above ethanol by every kilogram of Radix Salviae Miltiorrhizae and carry out percolation, be concentrated into the thick paste shape behind the diacolation liquid recycling ethanol, medicinal residues add a spot of water infusion, fully reclaim the salvia-soluble active ingredient in the medicinal residues, the medicinal liquid of enduring out also obtains paste with concentrating after filtration, and is standby with above-mentioned percolation thick paste merging.
3. make plain sheet
Exsiccant Radix Notoginseng stem piece is ground into 100 order fine powders, presses the prescription of medical material and Radix Salviae Miltiorrhizae thick paste and merge, carefully stir evenly, be added in the granulation machine and granulate, drying sprays into Lignum Dalbergiae Odoriferae oil by recipe ratio then, and it is standby to be pressed into plain sheet behind the mixing.
4. wrap sealing coat (two kinds of methods)
The above-mentioned plain sheet that makes is because be sprayed with Lignum Dalbergiae Odoriferae oil, adds that the Radix Notoginseng powder makes the Main Ingredients and Appearance of tablet, and depend merely on the easy oil impregnate of sugar coating layer, get damp, cracking, rotten, so the present invention wraps sealing coat ability sugar coating earlier with above-mentioned plain sheet.
(1) gelatin syrup sealing coat
Aqueous gelatin solution (5-10%), white sugar aqueous solution (65-75%), every kind of aqueous solution gets 50%, mix, then the above-mentioned plain sheet that makes is put in the coating pan, add the gelatin syrup, mixing, spill an amount of Pulvis Talci again, drying adds gelatin syrup for the second time again, so repeatedly, wrap the 3-6 layer altogether, the plain sheet of per kilogram needs gelatin syrup total amount 50-60 milliliter, obtains wrapping the semi-finished product of sealing coat.
(2) syrup acacia sealing coat
Arabic gum aqueous solution (20-30%), white sugar aqueous solution (65-75%), every kind of aqueous solution gets 50%, mix, by the syrupy method bag of above-mentioned bag gelatin syrup acacia sealing coat, it is the 50-60 milliliter that the plain sheet of per kilogram needs the total amount of Arabic syrup, wraps the 3-6 layer altogether, obtains wrapping the semi-finished product of sealing coat.
5. sugar coating
The method of Chinese medicine tablet or Western medicine sugar coating routinely, with the semi-finished product of wrapping sealing coat sugar coating 10-15 layer equably, (last one deck is the waxy luster layer), drying can be packed and be dispatched from the factory.
Characteristics of the present invention
1. calming nerves and activating blood circulation, heart-nourishing and Qi-benefiting, the blood vessel dilating that Radix Notoginseng, Radix Salviae Miltiorrhizae and three kinds of medicines of Lignum Dalbergiae Odoriferae oil are had, effect such as bring high blood pressure down completely puts together, and coronary heart disease is had higher therapeutical effect.
2. adopt and the general Chinese medicine tablet production method-Bao sealing coat different with Western medicine, because the Chinese medicine preparation of this tablet is more special, if there is not sealing coat, tablet is easy to crack, oil impregnate gets damp, expand blackout, go mouldy, quality is extremely unstable, when especially spring and summer rainy season or air humidity are big, more apt to deteriorate, and after having wrapped 3-6 layer sealing coat, because gum sugar has completely cut off the moisture content of infiltration inwards, tablet is kept dry, and increased the comprcssive strength of tablet, two kinds of tablets that the applicant will wrap sealing coat and not wrap sealing coat are deposited comparison, preserving more than 3 years of bag sealing coat, that does not wrap can only preserve half a year.
" GUANXIN DANSHEN PIAN " treatment medical record example that the inventive method is produced:
1. old * *, the man, 62 years old, Nanning city secondary school teachers, cardiopalmus appears from the mid-1970s, disease, Guangxi Medical College in 1978 such as uncomfortable in chest, headache are diagnosed as coronary heart disease with hypertension, through informal dress somedon, nitroglycerin etc., after the treatment of the military region, Guangxi out-patient department begins to take " GUANXIN DANSHEN PIAN ", two months, above-mentioned ill symptoms disappears, and no longer takes Western medicine and other Chinese medicine, and heart rate, blood pressure, cholesterol are all normal.
2. Sun Shui is handsome, the woman, people from Jing Dezhen, Jiangxi suffers from coronary heart disease for many years, the state of an illness is on the rise, the finger end has begun paralysis, has eaten many kinds of Western medicine, and is all ineffective, after eat " GUANXIN DANSHEN PIAN ", only eat one bottle all right.
Claims (2)
1, a kind of production method for the treatment of the coronary heart disease Chinese medicinal tablet, it is characterized in that this Radix Notoginseng that weight ratio is 40-55% that contains, the tablet manufacturing step of the Lignum Dalbergiae Odoriferae oil composition of the Radix Salviae Miltiorrhizae of 40-55% and 2-8% is: earlier Radix Salviae Miltiorrhizae is pulverized, with the ethanol percolation more than 90%, filter and obtain thick paste behind the liquid recovered alcohol, the medicinal residues infusion, concentrate and also make thick paste, both merge back and Radix Notoginseng powder mixing, make granule, dry, spray into and fall oil, be pressed into plain sheet, use gelatin syrup or Arabic syrup and Pulvis Talci bag 3-6 layer sealing coat then, the conventional pharmacy method of reuse is wrapped the sugarcoating layer of 10-15 layer.
2, production method according to claim 1 is characterized in that the step of wrapping gelatin syrup or syrup acacia sealing coat is:
(1) aqueous gelatin solution (5-10%), white sugar aqueous solution (65-75%) respectively gets 50%, mixes, and earlier plain sheet is put into coating pan, adds the gelatin syrup, and mixing is spilled into an amount of Pulvis Talci again, drying, 3-6 layer so repeatedly.
(2) arabic gum aqueous solution (20-30%), white sugar aqueous solution (65-75%), every kind of aqueous solution gets 50%, mixes, and earlier plain sheet put into coating pan, adds syrup acacia, and mixing is spilled into an amount of Pulvis Talci again, drying, 3-6 layer so repeatedly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92112338 CN1074121A (en) | 1992-10-24 | 1992-10-24 | A kind of production method for the treatment of the coronary heart disease Chinese medicinal tablet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92112338 CN1074121A (en) | 1992-10-24 | 1992-10-24 | A kind of production method for the treatment of the coronary heart disease Chinese medicinal tablet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1074121A true CN1074121A (en) | 1993-07-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 92112338 Pending CN1074121A (en) | 1992-10-24 | 1992-10-24 | A kind of production method for the treatment of the coronary heart disease Chinese medicinal tablet |
Country Status (1)
| Country | Link |
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| CN (1) | CN1074121A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002000235A1 (en) * | 2000-06-09 | 2002-01-03 | Rhk (Group) Co., Ltd. | A composition made of chinese medicinal herbs for treatment of coronary heart disease and angina pectoris and the process for the production thereof |
| CN100412545C (en) * | 2002-12-23 | 2008-08-20 | 北京采瑞医药有限公司 | Method for controlling quality of compound red sage root preparation used for treating cardio-cerebral vascualr disease |
| CN1778346B (en) * | 2004-11-26 | 2010-05-12 | 天津天士力制药股份有限公司 | Medicine for treating coronary heart disease |
| CN1778353B (en) * | 2004-11-26 | 2010-09-08 | 天津天士力制药股份有限公司 | Chinese medicine dropping ball for treating cardiovascular disease |
| CN1778352B (en) * | 2004-11-26 | 2010-11-10 | 天津天士力制药股份有限公司 | Chinese medicine composition for treating cardiovascular disease |
| CN104873908A (en) * | 2015-06-13 | 2015-09-02 | 济南邦文医药科技有限公司 | Traditional Chinese medicine for treating coronary heart disease with anxiety |
| CN110302169A (en) * | 2019-08-01 | 2019-10-08 | 张慧芬 | A kind of sliding film coated tablet and preparation method thereof |
| CN111142598A (en) * | 2019-12-30 | 2020-05-12 | 广州享药户联优选科技有限公司 | Internal environment control method and device of intelligent medicine chest |
| CN114712323A (en) * | 2022-05-18 | 2022-07-08 | 贵州奇源生物制品有限公司 | Human placenta tablet and preparation method thereof |
-
1992
- 1992-10-24 CN CN 92112338 patent/CN1074121A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002000235A1 (en) * | 2000-06-09 | 2002-01-03 | Rhk (Group) Co., Ltd. | A composition made of chinese medicinal herbs for treatment of coronary heart disease and angina pectoris and the process for the production thereof |
| CN100412545C (en) * | 2002-12-23 | 2008-08-20 | 北京采瑞医药有限公司 | Method for controlling quality of compound red sage root preparation used for treating cardio-cerebral vascualr disease |
| CN1778346B (en) * | 2004-11-26 | 2010-05-12 | 天津天士力制药股份有限公司 | Medicine for treating coronary heart disease |
| CN1778353B (en) * | 2004-11-26 | 2010-09-08 | 天津天士力制药股份有限公司 | Chinese medicine dropping ball for treating cardiovascular disease |
| CN1778352B (en) * | 2004-11-26 | 2010-11-10 | 天津天士力制药股份有限公司 | Chinese medicine composition for treating cardiovascular disease |
| CN104873908A (en) * | 2015-06-13 | 2015-09-02 | 济南邦文医药科技有限公司 | Traditional Chinese medicine for treating coronary heart disease with anxiety |
| CN110302169A (en) * | 2019-08-01 | 2019-10-08 | 张慧芬 | A kind of sliding film coated tablet and preparation method thereof |
| CN111142598A (en) * | 2019-12-30 | 2020-05-12 | 广州享药户联优选科技有限公司 | Internal environment control method and device of intelligent medicine chest |
| CN111142598B (en) * | 2019-12-30 | 2021-06-25 | 广州享药户联优选科技有限公司 | Internal environment control method and device of intelligent medicine chest |
| CN114712323A (en) * | 2022-05-18 | 2022-07-08 | 贵州奇源生物制品有限公司 | Human placenta tablet and preparation method thereof |
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