CN107397831A - It is a kind of with strengthening tendons warm up bone, dispelling wind and eliminating dampness, eliminating stagnation to stop pain effect Chinese medicine composition and preparation method thereof - Google Patents

It is a kind of with strengthening tendons warm up bone, dispelling wind and eliminating dampness, eliminating stagnation to stop pain effect Chinese medicine composition and preparation method thereof Download PDF

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CN107397831A
CN107397831A CN201710817574.1A CN201710817574A CN107397831A CN 107397831 A CN107397831 A CN 107397831A CN 201710817574 A CN201710817574 A CN 201710817574A CN 107397831 A CN107397831 A CN 107397831A
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臧星
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The invention discloses it is a kind of with strengthening tendons warm up bone, dispelling wind and eliminating dampness, eliminating stagnation to stop pain effect Chinese medicine composition.The Chinese traditional medicine composition includes according to mass fraction:12~32 parts of 30~60 parts of mashed potatoes, 15~35 parts of red ice powder, 2~14 parts of pungent numb powder and white wine.The Chinese medicine composition of the present invention is formed by the allotment meticulously of less medicine, so that effect of the ingredients in terms of bone, dispelling wind and eliminating dampness, cool blood detumescence, qi and activate blood circulation, eliminating stagnation to stop pain are warmed up for strengthening tendons mutually strengthens, obvious synergy is shown, further reduces drug side-effect.In addition, the Chinese medicine composition of the present invention is used for external application, focus is directly acted on, rapid-action, long action time, the diseases such as all kinds of soft tissue bruises, acute and chronic gout are controlled, it is evident in efficacy.

Description

It is a kind of with strengthening tendons warm up bone, dispelling wind and eliminating dampness, eliminating stagnation to stop pain effect Chinese medicine composition and Its preparation method
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to there is one kind strengthening tendons to warm up bone, dispelling wind and eliminating dampness, eliminating stagnation to stop pain effect Chinese medicine composition and preparation method thereof.
Background technology
Now with the development of society, job and life stress increase, daily life does not pay attention to, can be because each in daily life The reason for kind of various kinds and cause the diseases such as arthralgia, rheumatism, soft tissue injury and gout, the mostly exopathogen such as wind, cold, wet, heat Attack human body or muscles and bones hurt, impatency channels and collaterals, blood stasis and swelling pain, derangement of Qi and blood, channels and collaterals are not because caused by external force acts on human body Pass to internal organs and be damaged, with muscle, muscles and bones, joint is ached, numb, is weighed, joint stuffiness, even arthrocele is scorching hot etc. For the illness of main clinical manifestation.
Antibiotic medicine, brufen, feldene, naproxen, ACTH, sugared cortex are normally applied for above-mentioned illness doctor trained in Western medicine Hormone etc. is treated, and can only stablize the state of an illness mostly, it is impossible to effect a radical cure;What is more can also cause serious side effect to cause hepatic and renal function Infringement;Even if Emergent therapy effectively can not symptom management recurrence, and drug resistance and repellence can be produced, or even occur The complication such as Neuroleptic Leukocytopenia, cardiac function are impaired, hepatic and renal function impaired, stimulating intestine and stomach system, alpastic anemia.
Increasing expert thinks:From the organic conception of the traditional Chinese medical science, treated with traditional Chinese medicine integral syndrome differentiation, can yet be regarded as and control Treat the good footpath of another bar of above-mentioned disease;Not only the toxic side effect of Chinese medicine in itself greatly reduces, and can reduce Western medicine dose, gram Clothes take merely huge toxic side effect caused by Western medicine for a long time.But the Chinese Herbs for treating above-mentioned disease in the market are owed Good, patient, which still can only lean on, largely takes the larger Western medicine of toxic side effect to stablize the state of an illness.
Therefore develop it is a kind of shorten the course of disease, reduce that the Chinese medicine preparation of drug side-effect is very valuable, and traditional Chinese medicine is in this respect It is with the obvious advantage.
The content of the invention
It is an object of the invention to provide a kind of bone, dispelling wind and eliminating dampness, cool blood detumescence, eliminating stagnation to stop pain effect are warmed up with strengthening tendons Chinese medicine composition and preparation method thereof, antibiotic, hormone etc. chemicals are replaced with Chinese herbal medicine cheap and easy to get, to solve The problem of prior art is present.
To achieve the above object, first aspect present invention provides one kind, and there is the warm bone of strengthening tendons, dispelling wind and eliminating dampness, cool blood to disappear The swollen, Chinese medicine composition of eliminating stagnation to stop pain effect.Specifically, the Chinese traditional medicine composition includes according to mass fraction:Mashed potatoes 30~60 12~32 parts of part, 15~35 parts of red ice powder, 2~14 parts of pungent numb powder and white wine.
Preferably, the Chinese traditional medicine composition includes according to mass fraction:It is 40~50 parts of mashed potatoes, 20~30 parts of red ice powder, pungent 18~26 parts of 6~10 parts of numb powder and white wine.
Preferably, the Chinese traditional medicine composition includes according to mass fraction:45 parts of mashed potatoes, 25 parts of red ice powder, pungent numb 8 parts of powder With 22 parts of white wine.
Preferably, the red ice powder includes rde bean and borneol, and the mass ratio of the rde bean and borneol is 100:3.
Preferably, the pungent numb powder includes asarum powder and Chinese ephedra powder, and the mass ratio of the asarum powder and Chinese ephedra powder is 1:1.
Preferably, the white wine is 42~50 °.
Second aspect of the present invention provides a kind of warms up bone, dispelling wind and eliminating dampness, cool blood detumescence, eliminating stagnation to stop pain effect with strengthening tendons The preparation method of Chinese medicine composition.Specifically, the preparation method includes:By peeled potatoes, rde bean, borneol, asarum powder, fiber crops Bloom is co-located in medicine mortar or clean agitator, adds proper amount of white spirit grinding or mixing medicine puree is made in stirring, produce with strengthening tendons Warm bone, dispelling wind and eliminating dampness, cool blood detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect.
Third aspect present invention provides a kind of warms up bone, dispelling wind and eliminating dampness, cool blood detumescence, eliminating stagnation to stop pain effect with strengthening tendons The preparation method of Chinese medicine composition.Specifically, the preparation method comprises the following steps:
Step 1: asarum powder, Chinese ephedra powder are put into leaching medicine container, white wine is added to 2~3cm of powder excessively, closed immersion 72h, it is closed daily to shake 2~3 times, filtrate, medicine is made with the tentatively filtering of 3~4 layer of 80 mesh gauze in the decoction soaked in medicine container Slag squeezes out dead space capacity in the dregs of a decoction, merging filtrate and dead space capacity with squeezer, and admixing medical solutions are made, and closed storage is standby;
Step 2: being mixed under dregs of a decoction natural conditions after airing with rde bean, borneol, 80~200 mesh sieves are crossed after crushing and are made Mixed powder, closed storage are standby;
Step 3: mashed potatoes is made by being placed in medicine mortar or clean agitator to grind or stir after the clean peeling of potato, fill Enter be kept in dark place in brown glass container it is standby;
Step 4: by mixed powder and mashed potatoes with 1:2 or 1:3 mass ratio mixing, add appropriate admixing medical solutions stirring Into pastel, produce with strengthening tendons warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, eliminating stagnation to stop pain effect Chinese medicine composition.
The property of medicine and pharmacology of Chinese herbal medicine selected by the present invention are as follows:
Potato (mashed potatoes):It is sweet, it is mild-natured.Return stomach, large intestine channel.Major function:Stomachache, Zha ribs, carbuncle swells, eczema, scald. Used in being good for stomach, removing toxicity for detumescence.Modern medicine study find, potato contain much starch, protein, abundant vitamin and The trace elements such as calcium, potassium, the digesting of taste, wide intestines defaecation can be promoted, help the timely excretion metabolism toxin of body, prevent constipation, Prevent the generation of intestines problem;It can promote to hold the lubrication of alimentary canal, respiratory tract and articular cavity, serous cavity, prevention of cardiovascular and be The fat deposition of system, the elasticity of blood vessel is kept, be advantageous to the generation of prevention of arterial atherosis, also there is fat-reducing, keep blood vessel Elasticity, row's sodium protect the effect such as potassium.
Rde bean:It is sweet, sour, it is mild-natured.Thoughts of returning home warp, small intestinl channel.Major function:Inducing diuresis for removing edema, removing toxic substances apocenosis.For oedema Turgor, beriberi edema, jaundice, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess.Modern medicine study finds that rde bean contains Carbohydrate, triterpenoid saponin.Also-the p-D- of furancarbinol containing 3- glucopyranosides, red bean saponin(e, former Cyanidin, former Cyanidin, The compositions such as D- cachou extracts, D- epicatechins, nicotinic acid, riboflavin, make with rde bean with anti-oxidant, hypoglycemic, reducing blood lipid etc. With.
Borneol:Acrid flavour, bitter, cold in nature, the thoughts of returning home, Liver Channel.Major function:Lead to all keys, dissipate stagnated fire, remove screen improving eyesight, swelling and pain relieving. For apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm fan, deafness with qi stagnation, larynx numbness, aphtha, tympanitis, carbuncle swells, hemorrhoid, mesh also screen film, Enterobiasis.Modern pharmacological research finds that borneol is mainly borneol, isoborneol, camphor, containing a small amount of oxalene, beta-elemene, carypohyllene Etc. sequiterpene, the triterpene such as oleanolic acid, alphitolic acid, asiatic acid, dipterocarpol, dryobalanone, erythrodiol Compound, there is anti-inflammation, analgesic, antipruritic.
Asarum:Acrid flavour, it is warm-natured.The thoughts of returning home, lung, kidney channel.Major function:Relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping is sensible, Wenfei of drink. For anemofrigid cold, have a headache, toothache, arthralgia pain due to rheumatism, nasosinusitis, lung cold cough.Modern pharmacological research finds that asarum contains volatile oil, Main component methyl eugenol, eucarvone, safrole, nopinene, australene, borneol, different anisole, asarum ester are plain and a large amount of Trace element, there is local anaesthesia effect, there is a certain degree of inhibitory action to arthritis, also with certain bacteriostasis, Play the role of to strengthen lipid-metabolism and raise blood glucose, adjust body smooth muscle function.In addition, also have anti-inflammatory, it is anticonvulsion, analgesia, Effect that is calm, suppressing heating, antipyretic, antihistamine and antiallergic action and excited breathing.
Chinese ephedra:Acrid flavour, slight bitter, it is warm-natured.Return lung warp, bladder warp.Major function:Inducing sweat and dispelling exogenous evils, freeing lung and relieving asthma, Li Shui disappears It is swollen.Solved for table disease, asthma and cough.The effect of Chinese ephedra suede relaxes, suitable for old man, child and empty people's anemofrigid cold.Modern pharmacology Research finds that Chinese ephedra contains a variety of alkaloids and volatility alkali benzylmethylamine etc., wherein using ephedrine as principle active component, accounts for The 40%~90% of total alkaloid amount, separately containing Macro and microelements, sanedrine, pseudoephedrine, left-handed demethyl ephedrine, The compositions such as Chinese ephedra oxazolone, to cardiovascular system, have and intend adrenal gland energy effects on neural system;Have to respiratory system and relieving asthma, antibechic, dispel Phlegm acts on;Sweat gland secretion can be increased;With obvious diuresis;Make with anti-allergy action and certain anti-inflammatory With;Acted on refrigeration function and different degrees of resisting pathogenic microbes;Can excited maincenter, influence nervimuscular transmission;Have Choleretic effect, blood urea nitrogen and rise serum cholesterol can be reduced;Energy antiallergy, infected by influenza have inhibitory action;Ephedine Alkali can reduce blood pressure.
White wine:It is sweet, pungent, property heat.Return 12 warps.Major function:Warm taste, crux is broken, the efficacy of a drug is helped, thick stomach, preserves youthful looks Color, pass through blood vessels, nutrition skin.For controlling arthralgia pain due to rheumatism, numbness of extremities due to deficiency of blood;Steeping in wine medicine drinks it, can help dispensing power.Modern pharmacology is ground Study carefully discovery, white wine main component is alcohol and water, accounts for more than 99%, other to account for 1%, including fusel oil, polyalcohol, first Alcohol, aldehydes, acids, esters etc., there is prevention of cardiovascular disease, dispelling fatigue and anxiety, appetite-stimulating indigestion-relieving, expeling is cold, it is new to promote The effect of old metabolism and relaxing tendons and activating collaterals.
The invention has the advantages that:
1st, there is Chinese medicine composition of the invention strengthening tendons to warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, qi and activate blood circulation, eliminating stagnation to stop pain Effect, for exopathogen attack human body or because caused by external force acts on human body muscles and bones hurt, blood stasis and swelling pain, derangement of Qi and blood, Pain increase in intensity under coldness, to illnesss such as various types of soft tissue bruise, acute and chronic gout, cervical spondylopathy, arthritis, there is certain treatment effect Fruit, have no side effect simultaneously, no dependence.
2nd, Chinese medicine composition of the invention directly acts on focus in use, paste to be directly affixed on to illing skin surface, Medicine is not destroyed by digestive juice, can also be avoided because of the first pass effect of liver and decreasing effect, makes active ingredient in medicine can be with Faster, preferably absorbed by patient's affected area, rapid-action, long action time.
3rd, Chinese medicine composition of the invention uses pure Chinese medicinal preparation, avoids stimulation to patient's stomach and to caused by liver Toxic side effect, being put into practice by a large amount of crowds confirms, securely and reliably, no obvious adverse reaction, and preparation method is simple, to environment without Pollution, has great application value.
Embodiment
Following examples are used to illustrate the present invention, but are not limited to the scope of the present invention.
Embodiment 1
There is the present embodiment strengthening tendons to warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect, press It is prepared by following steps:
40 parts of potato decortications, 31.07 portions of rde beans, 0.93 part of borneol, 2 parts of asarum powders, 2 parts of Chinese ephedra powder are co-located in medicine mortar In, add the grinding of 30 parts of 42 ° of white wine and mixing medicine puree is made, produce and warm up bone with strengthening tendons, dispelling wind and eliminating dampness, cool blood detumescence, dissipating bind are stopped The Chinese medicine composition of pain effect.
Embodiment 2
There is the present embodiment strengthening tendons to warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect, press It is prepared by following steps:
50 parts of potato decortications, 14.56 portions of rde beans, 0.43 part of borneol, 7 parts of asarum powders, 7 parts of Chinese ephedra powder are co-located in cleaning In agitator, add the stirring of 18 parts of 44 ° of white wine and mixing medicine puree be made, produce with strengthening tendons warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, The Chinese medicine composition of eliminating stagnation to stop pain effect.
Embodiment 3
There is the present embodiment strengthening tendons to warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect, press It is prepared by following steps:
35 parts of potato decortications, 19.42 portions of rde beans, 0.58 part of borneol, 1 part of asarum powder, 1 part of Chinese ephedra powder are co-located in cleaning In agitator, add the stirring of 32 parts of 46 ° of white wine and mixing medicine puree be made, produce with strengthening tendons warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, The Chinese medicine composition of eliminating stagnation to stop pain effect.
Embodiment 4
There is the present embodiment strengthening tendons to warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect, press It is prepared by following steps:
60 parts of potato decortications, 24.27 portions of rde beans, 0.73 part of borneol, 5 parts of asarum powders, 5 parts of Chinese ephedra powder are co-located in medicine mortar In, add the grinding of 12 parts of 48 ° of white wine and mixing medicine puree is made, produce and warm up bone with strengthening tendons, dispelling wind and eliminating dampness, cool blood detumescence, dissipating bind are stopped The Chinese medicine composition of pain effect.
Embodiment 5
There is the present embodiment strengthening tendons to warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect, press It is prepared by following steps:
Step 1: 3.5 parts of asarum powders, 3.5 parts of Chinese ephedra powder are put into leaching medicine container, 16 parts of 50 ° of white wine, closed leaching are added 72h is steeped, it is closed daily to shake 3 times, filtrate, dregs of a decoction use is made with the tentatively filtering of 3 layer of 80 mesh gauze in the decoction soaked in medicine container Squeezer squeezes out dead space capacity in the dregs of a decoction, merging filtrate and dead space capacity, and admixing medical solutions are made, and closed storage is standby;
Step 2: being mixed under dregs of a decoction natural conditions after airing with 33.98 portions of rde beans, 1.02 parts of borneols, 100 are crossed after crushing Mixed powder is made in mesh sieve, and closed storage is standby;
Step 3: mashed potatoes is made by grinding in medicine mortar is placed in after the clean peeling of 30 portions of potatoes, load brown glass container Inside it is kept in dark place standby;
Step 4: by mixed powder and mashed potatoes with 1:2 mass ratio mixing, adds admixing medical solutions and stirs into pastel, Produce with strengthening tendons warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, eliminating stagnation to stop pain effect Chinese medicine composition.
Embodiment 6
There is the present embodiment strengthening tendons to warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect, press It is prepared by following steps:
Step 1: 6 parts of asarum powders, 6 parts of Chinese ephedra powder are put into leaching medicine container, 26 parts of 45 ° of white wine are added, closed immersion 72h, It is closed daily to shake 2 times, filtrate, dregs of a decoction squeezer is made with the tentatively filtering of 4 layer of 80 mesh gauze in the decoction soaked in medicine container Dead space capacity in the dregs of a decoction, merging filtrate and dead space capacity are squeezed out, admixing medical solutions are made, closed storage is standby;
Step 2: being mixed under dregs of a decoction natural conditions after airing with 20.39 portions of rde beans, 0.71 part of borneol, 80 are crossed after crushing Mixed powder is made in mesh sieve, and closed storage is standby;
Step 3: mashed potatoes is made by stirring in clean agitator is placed in after the clean peeling of 55 portions of potatoes, load brown glass It is kept in dark place in glass container standby;
Step 4: by mixed powder and mashed potatoes with 1:3 mass ratio mixing, adds admixing medical solutions and stirs into pastel, Produce with strengthening tendons warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, eliminating stagnation to stop pain effect Chinese medicine composition.
Embodiment 7
There is the present embodiment strengthening tendons to warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect, press It is prepared by following steps:
Step 1: 3 parts of asarum powders, 3 parts of Chinese ephedra powder are put into leaching medicine container, 20 parts of 48 ° of white wine are added, closed immersion 72h, It is closed daily to shake 3 times, filtrate, dregs of a decoction squeezer is made with the tentatively filtering of 4 layer of 80 mesh gauze in the decoction soaked in medicine container Dead space capacity in the dregs of a decoction, merging filtrate and dead space capacity are squeezed out, admixing medical solutions are made, closed storage is standby;
Step 2: being mixed under dregs of a decoction natural conditions after airing with 29.13 portions of rde beans, 0.87 part of borneol, 200 are crossed after crushing Mixed powder is made in mesh sieve, and closed storage is standby;
Step 3: being ground into mashed potatoes by being placed in after the clean peeling of 44 portions of potatoes in medicine mortar, load in brown glass container It is kept in dark place standby;
Step 4: by mixed powder and mashed potatoes with 1:2 mass ratio mixing, adds admixing medical solutions and stirs into pastel, Produce with strengthening tendons warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, eliminating stagnation to stop pain effect Chinese medicine composition.
Embodiment 8
There is the present embodiment strengthening tendons to warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect, press It is prepared by following steps:
Step 1: 4 parts of asarum powders, 4 parts of Chinese ephedra powder are put into leaching medicine container, 22 parts of 46 ° of white wine are added, closed immersion 72h, It is closed daily to shake 3 times, filtrate, dregs of a decoction squeezer is made with the tentatively filtering of 3 layer of 80 mesh gauze in the decoction soaked in medicine container Dead space capacity in the dregs of a decoction, merging filtrate and dead space capacity are squeezed out, admixing medical solutions are made, closed storage is standby;
Step 2: being mixed under dregs of a decoction natural conditions after airing with 17.48 portions of rde beans, 0.52 part of borneol, 180 are crossed after crushing Mixed powder is made in mesh sieve, and closed storage is standby;
Step 3: being ground into mashed potatoes by being placed in after the clean peeling of 45 portions of potatoes in medicine mortar, load in brown glass container It is kept in dark place standby;
Step 4: by mixed powder and mashed potatoes with 1:2 mass ratio mixing, adds admixing medical solutions and stirs into pastel, Produce with strengthening tendons warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, eliminating stagnation to stop pain effect Chinese medicine composition.
The embodiment of the present invention 1~4 and embodiment 5~8 two kind preparation method be obtained have strengthening tendons warm up bone, dispelling wind and eliminating dampness, The Chinese medicine composition of cool blood detumescence, eliminating stagnation to stop pain effect, further it is made respectively using various preservation technologies and packing technique Kind external-use drug form is used for clinical and storage.
It is as follows for proof curative effect of the present invention, clinical test:
Case-data:Acute or chronic soft tissue injury patient 320, wherein acute soft tissue injury 160 are randomly selected, slowly Property soft tissue injury 160.
Case screening criteria:All soft tissue closeds such as muscle, ligament, tendon, manadesma as caused by wound strain exopathogen The patient of damage can include.
Administrated method and the course for the treatment of:In batches respectively using apply example 1~8 prepare have strengthening tendons warm up bone, dispelling wind and eliminating dampness, cool blood Detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect, affected part, outer wrapping thin film are spread on during use.Within 12 hours The wounded, coordinate cold compress as far as possible;The wounded can coordinate hot compress within more than 12 hours.24 to 48h dressings once, severe injury then can be one day Change twice.The one Monday course for the treatment of, treatment observe curative effect after two weeks.
Curative effect judging standard:
Recovery from illness:Local pain, swelling and the dermal ecchymosis disappear after medication, and functional activity recovers normal;
It is effective:Local pain mitigates significantly after medication, and swelling and the dermal ecchymosis disappear substantially, and functional activity recovers just substantially Often;
Effectively:Local pain mitigates after medication, and swelling and the dermal ecchymosis have disappeared, and functional activity has recovered;
It is invalid:Local pain, swelling and the dermal ecchymosis do not have change after medication.
Table 1 is being warmed up with strengthening tendons in bone, dispelling wind and eliminating dampness, cool blood detumescence, eliminating stagnation to stop pain effect for the preparation of embodiment 1~8 Treatment results of the drug composition to 320 acute and chronic soft tissue injury patients.
Table 1
From table 1 it follows that acute and chronic soft tissue injury patient has strengthening tendons to warm up using what embodiment 1~8 was prepared Bone, dispelling wind and eliminating dampness, cool blood detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect, first course for the treatment of effective percentage have reached 94.4%, Efficient two courses for the treatment of are 100%, cure rate 96.9%, to the far super existing product of therapeutic effect of acute and chronic soft tissue injury. In addition, all patients are showed no obvious adverse reaction.
Case-data:Patient with gout 60 is randomly selected, classical symptom is the serious pain in joint, swelling, erythema, deadlock Firmly, generate heat, palpitaition, shiver with cold etc..
Administrated method and the course for the treatment of:In batches respectively using apply example 1~8 prepare have strengthening tendons warm up bone, dispelling wind and eliminating dampness, cool blood Detumescence, the Chinese medicine composition of eliminating stagnation to stop pain effect, affected part, outer wrapping thin film are spread on during use.One day one to two doses, Continuous treatment observes curative effect after three weeks.
Curative effect judging standard:
It is effective:Gout symptom disappears, and recovers normal, recovery from illness;
Take a turn for the better:Patient articular's pain, swelling, erythema, stiff, heating, palpitaition, the phenomenon of shiver with cold mitigate, and gout symptom is obvious Take a turn for the better, progressively recover normal;
It is invalid:The patient of improvement and above standard is not reached.
Table 2 is being warmed up with strengthening tendons in bone, dispelling wind and eliminating dampness, cool blood detumescence, eliminating stagnation to stop pain effect for the preparation of embodiment 1~8 Treatment results of the drug composition to 60 patient with gout
Table 2
From Table 2, it can be seen that in above-mentioned treatment, with the present invention there is the warm bone of strengthening tendons, dispelling wind and eliminating dampness, cool blood to disappear Swollen, the traditional Chinese medicine composition for treating patient with gout 60 of eliminating stagnation to stop pain effect, as a result effective 52, obvious effective rate 86.67%;Take a turn for the better 6, improvement rate 10.00%;Invalid 2, total effective rate 96.67%, and there are no in 60 patients obvious bad anti- Should.
To prove that the present invention has the effect of fine, it is as follows to enumerate model case:
Zhang, man, 48 years old, make 10 years during right sufficient halluces pain, early work one week.Inscribe and see local red and swollen heat pain, body It is sturdy, it is bellied.It is greedy cool that heat is disliked usually, pain during shoulder neck.Pink tongue, yellow tongue fur, if the cunning number that floating pulse is pressed is strong.With embodiment 2 Obtained drug therapy is after two weeks, symptom mitigation, is cured after a two weeks, and freely, follow-up 1 year is without recurrence for joint motion.
Certain is revived, man, 38 years old, toe, ankle-joint, knee joint were red and swollen, heat pain, knee articulation inconvenience.It is made with embodiment 4 Drug therapy after one week, symptom mitigation, cured after two weeks, follow-up is without recurrence.
Huang, man, 41 years old, left foot back pain one week, it had gout medical history for many years, the tired recurrence of one week cause, through doctor trained in Western medicine Treatment is not imitated.Inscribe and see local red and swollen heat pain, body is fat, and pink tongue, yellow tongue fur cover is white, and the cunning number that floating pulse is pressed is strong.With implementation Drug therapy made from example 6 symptom mitigation, is cured, follow-up is without recurrence after one week after being continuing with three weeks.
Xue, rural migrant worker, 52 years old, patient started brothers joint and oedema heat pain phenomenon occurs before 2 years, night is often by pain Wake up, especially cold day is gout through hospital diagnosis more very, once takes the Western medicine such as the general life of phenylbutazone, tea, symptom alleviated but Easily recurred after drug withdrawal.Finger-joint and right podarthrum stiff oedema when to go to a doctor at inventor, and have ulceration phenomenon, with implementation After three weeks, arthroedema and ulceration phenomenon substantially mitigate drug therapy made from example 8, are cured after being continuing with three weeks, slight illness is fullyed recover from an illness More and so far there are no recurrence.
Although above with general explanation and specific embodiment, the present invention is described in detail, at this On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore, These modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to the scope of protection of present invention.

Claims (8)

1. a kind of there is strengthening tendons to warm up bone, dispelling wind and eliminating dampness, the Chinese medicine composition of eliminating stagnation to stop pain effect, it is characterised in that:The Chinese medicine Combination includes according to mass fraction:30~60 parts of mashed potatoes, 15~35 parts of red ice powder, 2~14 parts of pungent numb powder and white wine 12~32 Part.
2. according to claim 1 there is strengthening tendons to warm up bone, dispelling wind and eliminating dampness, the Chinese medicine composition of eliminating stagnation to stop pain effect, it is special Sign is:The Chinese traditional medicine composition includes according to mass fraction:40~50 parts of mashed potatoes, 20~30 parts of red ice powder, pungent numb powder 6~10 18~26 parts of part and white wine.
3. according to claim 1 there is strengthening tendons to warm up bone, dispelling wind and eliminating dampness, the Chinese medicine composition of eliminating stagnation to stop pain effect, it is special Sign is:The Chinese traditional medicine composition includes according to mass fraction:45 parts of mashed potatoes, 25 parts of red ice powder, 8 parts of pungent numb powder and white wine 22 Part.
4. according to claim any one of 1-3 there is strengthening tendons to warm up bone, dispelling wind and eliminating dampness, the Chinese traditional medicine composition of eliminating stagnation to stop pain effect Thing, it is characterised in that:The red ice powder includes rde bean and borneol, and the mass ratio of the rde bean and borneol is 100:3.
5. according to claim any one of 1-3 there is strengthening tendons to warm up bone, dispelling wind and eliminating dampness, the Chinese traditional medicine composition of eliminating stagnation to stop pain effect Thing, it is characterised in that:The pungent numb powder includes asarum powder and Chinese ephedra powder, and the mass ratio of the asarum powder and Chinese ephedra powder is 1:1.
6. according to claim any one of 1-3 there is strengthening tendons to warm up bone, dispelling wind and eliminating dampness, the Chinese traditional medicine composition of eliminating stagnation to stop pain effect Thing, it is characterised in that:The white wine is 42~50 °.
7. it is a kind of with strengthening tendons warm up bone, dispelling wind and eliminating dampness, eliminating stagnation to stop pain effect Chinese medicine composition preparation method, its feature exists In:The preparation method includes:Peeled potatoes, rde bean, borneol, asarum powder, Chinese ephedra powder are co-located in medicine mortar or clean stirring In device, add proper amount of white spirit grinding or stirring mixing medicine puree is made, produce with strengthening tendons warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, dissipate Tie the Chinese medicine composition of analgesic efficacy.
8. it is a kind of with strengthening tendons warm up bone, dispelling wind and eliminating dampness, eliminating stagnation to stop pain effect Chinese medicine composition preparation method, its feature exists In:The preparation method comprises the following steps:
Step 1: asarum powder, Chinese ephedra powder are put into leaching medicine container, white wine is added to powder 2~3cm, closed immersion 72h is crossed, often Its closed shaking 2~3 times, is made filtrate, the dregs of a decoction are pressed by the decoction soaked in medicine container with the tentatively filtering of 3~4 layer of 80 mesh gauze Crusher squeezes out dead space capacity in the dregs of a decoction, merging filtrate and dead space capacity, and admixing medical solutions are made, and closed storage is standby;
Step 2: being mixed under dregs of a decoction natural conditions after airing with rde bean, borneol, 80~200 mesh sieves are crossed after crushing mixing is made Medicinal powder, closed storage are standby;
Step 3: mashed potatoes is made by being placed in medicine mortar or clean agitator to grind or stir after the clean peeling of potato, load brown It is kept in dark place in color glass container standby;
Step 4: by mixed powder and mashed potatoes with 1:2 or 1:3 mass ratio mixing, adds appropriate admixing medical solutions and stirs into paste Shape thing, produce with strengthening tendons warm up bone, dispelling wind and eliminating dampness, cool blood detumescence, eliminating stagnation to stop pain effect Chinese medicine composition.
CN201710817574.1A 2017-09-12 2017-09-12 It is a kind of with strengthening tendons warm up bone, dispelling wind and eliminating dampness, eliminating stagnation to stop pain effect Chinese medicine composition and preparation method thereof Pending CN107397831A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2748081Y (en) * 2004-11-27 2005-12-28 崔连光 Plaster for soft tissue injury
CN105596617A (en) * 2016-03-17 2016-05-25 江苏至善堂药业有限公司 Medicine for protecting joints and preparation method of medicine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2748081Y (en) * 2004-11-27 2005-12-28 崔连光 Plaster for soft tissue injury
CN105596617A (en) * 2016-03-17 2016-05-25 江苏至善堂药业有限公司 Medicine for protecting joints and preparation method of medicine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
陈克雄: "中医药治疗肩关节周围炎92例探讨", 《中国中医基础医学杂志》 *

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