CN107397029A - A kind of blueberry lutein ester pressed candy - Google Patents
A kind of blueberry lutein ester pressed candy Download PDFInfo
- Publication number
- CN107397029A CN107397029A CN201710598385.XA CN201710598385A CN107397029A CN 107397029 A CN107397029 A CN 107397029A CN 201710598385 A CN201710598385 A CN 201710598385A CN 107397029 A CN107397029 A CN 107397029A
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- blueberry
- lutein ester
- pressed candy
- chinese medical
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- 235000003095 Vaccinium corymbosum Nutrition 0.000 title claims abstract description 51
- 235000017537 Vaccinium myrtillus Nutrition 0.000 title claims abstract description 51
- 235000021014 blueberries Nutrition 0.000 title claims abstract description 51
- 240000000851 Vaccinium corymbosum Species 0.000 title claims abstract description 45
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 title claims abstract description 43
- 235000009508 confectionery Nutrition 0.000 title claims abstract description 32
- 239000000284 extract Substances 0.000 claims abstract description 35
- 239000000843 powder Substances 0.000 claims abstract description 19
- 240000002234 Allium sativum Species 0.000 claims abstract description 14
- 235000004611 garlic Nutrition 0.000 claims abstract description 14
- 150000004676 glycans Chemical class 0.000 claims abstract description 14
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 14
- 239000005017 polysaccharide Substances 0.000 claims abstract description 14
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 13
- 229930195725 Mannitol Natural products 0.000 claims abstract description 13
- 239000000594 mannitol Substances 0.000 claims abstract description 13
- 235000010355 mannitol Nutrition 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 13
- 241000205585 Aquilegia canadensis Species 0.000 claims description 11
- 240000003915 Lophatherum gracile Species 0.000 claims description 11
- 244000197580 Poria cocos Species 0.000 claims description 11
- 235000008599 Poria cocos Nutrition 0.000 claims description 11
- 235000001855 Portulaca oleracea Nutrition 0.000 claims description 10
- 244000077233 Vaccinium uliginosum Species 0.000 claims description 6
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 2
- 229910052749 magnesium Inorganic materials 0.000 claims 2
- 239000011777 magnesium Substances 0.000 claims 2
- DCXXMTOCNZCJGO-UHFFFAOYSA-N tristearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC DCXXMTOCNZCJGO-UHFFFAOYSA-N 0.000 claims 2
- 244000228367 Lewisia rediviva Species 0.000 claims 1
- 235000007279 Lewisia rediviva Nutrition 0.000 claims 1
- 244000234609 Portulaca oleracea Species 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract description 22
- 208000003464 asthenopia Diseases 0.000 abstract description 11
- 235000019359 magnesium stearate Nutrition 0.000 abstract description 11
- 238000002360 preparation method Methods 0.000 abstract description 8
- 238000000034 method Methods 0.000 abstract description 7
- 230000036541 health Effects 0.000 abstract description 6
- 230000004438 eyesight Effects 0.000 abstract description 3
- 230000007774 longterm Effects 0.000 abstract description 3
- 230000000295 complement effect Effects 0.000 abstract description 2
- 238000009776 industrial production Methods 0.000 abstract description 2
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- 238000007254 oxidation reaction Methods 0.000 abstract description 2
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- 238000003860 storage Methods 0.000 abstract description 2
- 210000001508 eye Anatomy 0.000 description 26
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 14
- 241000219304 Portulacaceae Species 0.000 description 9
- 208000024891 symptom Diseases 0.000 description 8
- 239000000243 solution Substances 0.000 description 7
- 239000003814 drug Substances 0.000 description 6
- 150000002148 esters Chemical class 0.000 description 6
- 229960005375 lutein Drugs 0.000 description 6
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 description 6
- 235000012680 lutein Nutrition 0.000 description 6
- 239000001656 lutein Substances 0.000 description 6
- 230000035807 sensation Effects 0.000 description 6
- 235000019615 sensations Nutrition 0.000 description 6
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 description 6
- 238000010792 warming Methods 0.000 description 6
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 description 6
- 206010034960 Photophobia Diseases 0.000 description 5
- 206010047513 Vision blurred Diseases 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 238000005469 granulation Methods 0.000 description 4
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- 206010025482 malaise Diseases 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
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- 239000011122 softwood Substances 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 3
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- 235000013305 food Nutrition 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 206010019233 Headaches Diseases 0.000 description 2
- 239000004677 Nylon Substances 0.000 description 2
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
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- 239000007788 liquid Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 229920001778 nylon Polymers 0.000 description 2
- 238000005057 refrigeration Methods 0.000 description 2
- 239000002893 slag Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 238000007619 statistical method Methods 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 238000009777 vacuum freeze-drying Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 235000020985 whole grains Nutrition 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 241000905957 Channa melasoma Species 0.000 description 1
- 208000028006 Corneal injury Diseases 0.000 description 1
- 206010057315 Daydreaming Diseases 0.000 description 1
- 208000003164 Diplopia Diseases 0.000 description 1
- -1 Flavine ester Chemical class 0.000 description 1
- 208000010412 Glaucoma Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 244000283207 Indigofera tinctoria Species 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
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- 230000000172 allergic effect Effects 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000021028 berry Nutrition 0.000 description 1
- 210000005252 bulbus oculi Anatomy 0.000 description 1
- 210000004087 cornea Anatomy 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 208000027993 eye symptom Diseases 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000004410 intraocular pressure Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
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- 235000015096 spirit Nutrition 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
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- 238000002562 urinalysis Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of blueberry lutein ester pressed candy, is made of the raw material of following parts by weight:28 48 parts of blueberry freeze-dried powder, 10 15 parts of lutein ester, 8 12 parts of garlic polysaccharide, 10 15 parts of Chinese medical extract, 20 30 parts of mannitol, 37 parts of magnesium stearate;The invention also discloses the preparation method of the blueberry lutein ester pressed candy.The blueberry lutein ester pressed candy each component compatibility science of the present invention, is complementary to one another, and fully meets requirement of the people to health;Oxidation resistance is strong, not only has the function that to alleviate visual fatigue and protects eyesight, and instant, easy to process, storage and transport, is adapted to large-scale industrial production;The garlic polysaccharide and Chinese medical extract of addition, the bioavilability of blueberry freeze-dried powder and lutein ester can be significantly increased, formula is reasonable, excellent taste, is adapted to long-term consumption.
Description
Technical field
The present invention relates to food processing technology field, particularly a kind of blueberry lutein ester pressed candy.
Background technology
Visual fatigue is also known as kopiopia, is mainly shown as vision disorder, during such as close eye, occur eye-blurred, ghost image,
Word row is overlapping, word jump;When seeing distant place again after seeing closely, a moment is needed gradually to see clearly.Eye symptom have eye is sleepy, keep in dark place,
Eyelid is heavy, the swollen sense of acid or pain around difficulty in opening the eyes, eyeball and eye socket, sheds tears, foreign body sensation, the dry and astringent, saccade of eye etc..Sternly
Pay attention to tired patient and also have different degrees of constitutional symptom, such as headache, dizzy, powerless, nausea and vomiting.
The illness in eye of visual fatigue and dependent, but based on patient's subjective symptoms, eye or whole body apparatus factors with
The syndrome that psychologic factors are interweaved, also commonly known as kopiopia syndrome.Outside environmental elements are to cause visual fatigue
Major reason, as illumination is insufficient or too strong, distribution of light sources is uneven or glimpses, and fixation object is too small, meticulous or unstable
It is fixed etc..In addition, some illness in eye and systemic disease also result in the generation of visual fatigue, everybody should enhance your vigilance.
Except kopiopia, eye is dry and astringent, foreign body sensation, eyelid sense of heaviness, blurred vision, photophobia is shed tears, eye distending pain and eye are filled
Blood etc., visual fatigue be also possible to cause more obstinate headache, giddy, nausea, One's spirits are drooping, absent minded, decrease of memory,
Poor appetite, and the symptom such as neck shoulder aching pain in waist and back and articulations digitorum manus numbness;Minority is it may also occur that diplopia, stereoscopic vision function barrier
Hinder, intraocular pressure rise, corneal injury etc.;There are glaucoma, eye surface or other eye disease patients can also trigger or add because of " visual fatigue "
The original illness in eye of weight;In addition, visual fatigue is also possible to cause early ageing and the reduction of body immunity.
The medicine or health products of various alleviation visual fatigues are currently there are, but in most drug
Containing toxin or with side effect, and a kind of snacks that candy, which is people, to be liked, but candy in the market only with
Based on sour-sweet taste, help is had no to the health of human body, and sometimes candy is overeated and is also easy to induced Diabetic, decayed tooth etc.
Illness.
The content of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of blueberry lutein ester pressed candy.
The purpose of the present invention is achieved by the following technical solution:
A kind of blueberry lutein ester pressed candy, it is made of the raw material of following parts by weight:Blueberry freeze-dried powder 28-48 parts, leaf
Flavine ester 10-15 parts, garlic polysaccharide 8-12 parts, Chinese medical extract 10-15 parts, mannitol 20-30 parts, magnesium stearate 3-7 parts;
The Chinese medical extract is according to 1 by purslane, lophatherum gracile, Poria cocos and honeysuckle:0.5-1:0.7-0.9:0.4-0.6's
Made from weight ratio.
Preferably, a kind of blueberry lutein ester pressed candy, it is made of the raw material of following parts by weight:Blueberry freeze-dried powder
38 parts, 13 parts of lutein ester, 10 parts of garlic polysaccharide, 12 parts of Chinese medical extract, 25 parts of mannitol, 5 parts of magnesium stearate.
Preferably, Chinese medical extract is according to 1 by purslane, lophatherum gracile, Poria cocos and honeysuckle:0.7:0.8:0.5 weight
Made from amount ratio.
A kind of preparation method of blueberry lutein ester pressed candy, is prepared by following steps:
1)The preparation of blueberry freeze-dried powder:Take the blueberries of fresh clean to be sterilized with Ozone Water, it is pre- to load extremely less than -35 DEG C of lyophilized plate
It is cold, fruit is crushed when central temperature reaches -25 DEG C, being cooled to temperature is down to less than -30 DEG C in advance for continuation, then carries out vacuum refrigeration
Dry, vacuum 50pa, -35 DEG C of cold hydrazine temperature;Material is heated using temperature programming;Heating and rate of temperature fall are
2.0℃/min;Heating schedule is:0-1h is warming up to 50 DEG C, is cooled to 42 DEG C, is incubated 4-5h;45 DEG C are warming up to, is incubated 3-5h;
50 DEG C are warming up to, is incubated 1-2h;55 DEG C of insulation 3-5h, control blueberry moisture stops vacuum freeze drying when being less than 6%, naturally cold
But blueberry freeze-dried powder is obtained afterwards;
2)The preparation of Chinese medical extract:Purslane, lophatherum gracile, Poria cocos and honeysuckle are mixed according to parts by weight, add 4 times of raw materials
The concentration of gross weight is 80% ethanol, is heated to reflux 50min, and filtering obtains the first extract solution;3 times of medicines are added into the dregs of a decoction
The concentration of slag weight is 90% ethanol, is heated to reflux 40min, filters to obtain the second extract solution;First extract solution and second are extracted
Liquid merges, and is concentrated under reduced pressure and removes ethanol, dries, gets dry extract;Dry cream is placed in micronizer and crushes 1h, sieves, obtains 200
Purpose Chinese medical extract;
3)Mixing:Blueberry freeze-dried powder, lutein ester, garlic polysaccharide, Chinese medical extract, mannitol and magnesium stearate are mixed equal
It is even, obtain compound;
4)Granulation:Compound is used into Boiling Fuel Injection Spray granulation technique softwood, softwood system with the 65% food grade alcohol containing PVP
It is put into after good in oscillating granulator, crosses 14 mesh nylon mesh and pelletized, then dried, dried particle is placed again into the system of waving
Whole grain is carried out in grain machine, crosses 60 mesh sieves;
5)Tabletting:The particle that will be made, tabletting is carried out with rotary tablet machine, tabletting is packed, and blueberry lutein ester is made
Pressed candy.
Specification:0.5g/ pieces.
Beneficial effects of the present invention:
1. the blueberry lutein ester pressed candy each component compatibility science of the present invention, is complementary to one another, fully meets people to health
Requirement.
2. the blueberry lutein ester pressed candy oxidation resistance of the present invention is strong, not only there is alleviation visual fatigue and protection to regard
The effect of power, and instant, easy to process, storage and transport, are adapted to large-scale industrial production, have wide market
Prospect.
3. the garlic polysaccharide and Chinese medical extract of the blueberry lutein ester pressed candy addition of the present invention, can significantly increase indigo plant
The bioavilability of certain kind of berries freeze-dried powder and lutein ester, formula is reasonable, excellent taste, is adapted to long-term consumption.
Embodiment
Technical scheme is further described in detail with reference to specific embodiment.
Embodiment 1
A kind of blueberry lutein ester pressed candy, it is made of the raw material of following parts by weight:48 parts of blueberry freeze-dried powder, lutein
10 parts of ester, 8 parts of garlic polysaccharide, 15 parts of Chinese medical extract, 20 parts of mannitol, 3 parts of magnesium stearate;
The Chinese medical extract is according to 1 by purslane, lophatherum gracile, Poria cocos and honeysuckle:0.5:0.9:0.4 weight is than being made
's.
A kind of preparation method of blueberry lutein ester pressed candy, is prepared by following steps:
1)The preparation of blueberry freeze-dried powder:Take the blueberries of fresh clean to be sterilized with Ozone Water, it is pre- to load extremely less than -35 DEG C of lyophilized plate
It is cold, fruit is crushed when central temperature reaches -25 DEG C, being cooled to temperature is down to less than -30 DEG C in advance for continuation, then carries out vacuum refrigeration
Dry, vacuum 50pa, -35 DEG C of cold hydrazine temperature;Material is heated using temperature programming;Heating and rate of temperature fall are
2.0℃/min;Heating schedule is:0-1h is warming up to 50 DEG C, is cooled to 42 DEG C, is incubated 4-5h;45 DEG C are warming up to, is incubated 3-5h;
50 DEG C are warming up to, is incubated 1-2h;55 DEG C of insulation 3-5h, control blueberry moisture stops vacuum freeze drying when being less than 6%, naturally cold
But blueberry freeze-dried powder is obtained afterwards;
2)The preparation of Chinese medical extract:Purslane, lophatherum gracile, Poria cocos and honeysuckle are mixed according to parts by weight, add 4 times of raw materials
The concentration of gross weight is 80% ethanol, is heated to reflux 50min, and filtering obtains the first extract solution;3 times of medicines are added into the dregs of a decoction
The concentration of slag weight is 90% ethanol, is heated to reflux 40min, filters to obtain the second extract solution;First extract solution and second are extracted
Liquid merges, and is concentrated under reduced pressure and removes ethanol, dries, gets dry extract;Dry cream is placed in micronizer and crushes 1h, sieves, obtains 200
Purpose Chinese medical extract;
3)Mixing:Blueberry freeze-dried powder, lutein ester, garlic polysaccharide, Chinese medical extract, mannitol and magnesium stearate are mixed equal
It is even, obtain compound;
4)Granulation:Compound is used into Boiling Fuel Injection Spray granulation technique softwood, softwood system with the 65% food grade alcohol containing PVP
It is put into after good in oscillating granulator, crosses 14 mesh nylon mesh and pelletized, then dried, dried particle is placed again into the system of waving
Whole grain is carried out in grain machine, crosses 60 mesh sieves;
5)Tabletting:The particle that will be made, tabletting is carried out with rotary tablet machine, tabletting is packed, and blueberry lutein ester is made
Pressed candy.
Specification:0.5g/ pieces.
Embodiment 2
A kind of blueberry lutein ester pressed candy, it is made of the raw material of following parts by weight:43 parts of blueberry freeze-dried powder, lutein
12 parts of ester, 9 parts of garlic polysaccharide, 14 parts of Chinese medical extract, 23 parts of mannitol, 4 parts of magnesium stearate;
The Chinese medical extract is according to 1 by purslane, lophatherum gracile, Poria cocos and honeysuckle:0.6:0.8:0.5 weight is than being made
's.
Remaining is the same as embodiment 1.
Embodiment 3
A kind of blueberry lutein ester pressed candy, it is made of the raw material of following parts by weight:38 parts of blueberry freeze-dried powder, lutein
13 parts of ester, 10 parts of garlic polysaccharide, 12 parts of Chinese medical extract, 25 parts of mannitol, 5 parts of magnesium stearate.
The Chinese medical extract is according to 1 by purslane, lophatherum gracile, Poria cocos and honeysuckle:0.7:0.8:0.5 weight ratio
It is obtained.
Remaining is the same as embodiment 1.
Embodiment 4
A kind of blueberry lutein ester pressed candy, it is made of the raw material of following parts by weight:33 parts of blueberry freeze-dried powder, lutein
14 parts of ester, 11 parts of garlic polysaccharide, 11 parts of Chinese medical extract, 28 parts of mannitol, 6 parts of magnesium stearate;
The Chinese medical extract is according to 1 by purslane, lophatherum gracile, Poria cocos and honeysuckle:0.8:0.8:0.5 weight is than being made
's.
Remaining is the same as embodiment 1.
Embodiment 5
A kind of blueberry lutein ester pressed candy, it is made of the raw material of following parts by weight:28 parts of blueberry freeze-dried powder, lutein
15 parts of ester, 12 parts of garlic polysaccharide, 10 parts of Chinese medical extract, 30 parts of mannitol, 7 parts of magnesium stearate;
The Chinese medical extract is according to 1 by purslane, lophatherum gracile, Poria cocos and honeysuckle:1:0.7:0.6 weight is than being made
's.
Remaining is the same as embodiment 1.
Comparative example
A kind of blueberry lutein ester pressed candy, it is made of the raw material of following parts by weight:48 parts of blueberry freeze-dried powder, lutein
25 parts of ester, 25 parts of mannitol, 5 parts of magnesium stearate.
Remaining is the same as embodiment 1.
Clinical data
General information:Issued according to the Ministry of Public Health《Health food is examined and assessment technique enforcement of regulations handbook》Select subject couple
As the age easily produces the people of visual fatigue study subject 300 with eye for a long time between 21-42 year, is randomly divided into experimental group and control
Group, every group of each 150 people, 2 groups of general information comparing differences are counted without Tong and learn Yi Yi ﹙ P>0.05 ﹚, there is comparativity.
Exclusion standard:(1)With infectious, traumatic eye disease patient, less than three months persons of operated eye are carried out;
(2)With eye disease patient inside and outside cornea, crystal, vitreum, eyeground pathological changes etc.;(3)With angiocarpy, the cerebrovascular, liver, kidney, make
The disease patient such as blood system;(4)Gestation or women breast-feeding their children, allergic constitution patient;(5)Take in a short time related to tested function
Medicine, have influence on the judgement person to result;(6)The medicine of long-term use of relevant treatment eyesight, health products or uses other treatment
Method fails termination person;(7)Do not meet inclusive criteria, not by the edible tested material person of regulation, or the not congruent influence effect of data or
Security judgement person.
Treatment method:Experimental group takes the blueberry lutein ester pressed candy of the present invention, and control group takes comparative example preparation
Blueberry lutein ester pressed candy, twice daily, each two panels, chew.Continuously take 60 days.
Curative effect determinate standard:Subject's eye is ached, eye is swollen for observation, photophobia, blurred vision, eye are dry and astringent, foreign body sensation, shed tears,
8 kinds of main clinic symptoms of general malaise.
Improve:Eye is ached, eye is swollen, photophobia, blurred vision, eye are dry and astringent, foreign body sensation, is shed tears, 8 kinds of Major Clinicals of general malaise
There are more than three kinds to improve in symptom, and other symptoms are without deterioration;
Take a turn for the better:Eye is ached, eye is swollen, photophobia, blurred vision, eye are dry and astringent, foreign body sensation, is shed tears, 8 kinds of main clinic symptoms of general malaise
In at least a kind of improve;
It is invalid:Eye is ached, eye is swollen, photophobia, blurred vision, eye are dry and astringent, foreign body sensation, is shed tears, 8 kinds of main clinic symptoms of general malaise
Do not improve, or have deterioration.
Total effective rate=[ ﹙ improve+Hao Zhuan ﹚/total number of cases ] × 100%.
Statistical method:Statistical analysis is carried out using SPSS17.0 statistical softwares, measurement data is with the quasi- Cha ﹙ of mean ± Biao
xo± s ﹚ are represented, are examined using t, the comparison of enumeration data rate uses χ2Examine.
Treatment results:The treatment results for the treatment of group and control group are shown in Table 1.
The treatment results of the application of table 1 blueberry lutein ester pressed candy of the present invention
Group | Improvement/example | Improvement/example | Invalid/example | Total effective rate/% |
Experimental group | 83 | 41 | 26 | 82.7 |
Control group | 41 | 38 | 71 | 52.7 |
Compared with control group, P < 0.05.
As shown in Table 1, treatment group improves 83, takes a turn for the better 41, invalid 26, total effective rate 82.7%;Control group improves
41, take a turn for the better 38, invalid 71, total effective rate 52.7%.2 groups of cure rates and total effective rate comparing difference have statistics meaning
Yi ﹙ P<0.05 ﹚, treatment group's curative effect are better than control group.
The blueberry lutein ester pressed candy of the present invention is edible front and rear, blood routine, just routine urinalysis, routine and blood biochemistry index
In normal range (NR), illustrate that this product has no adverse effects to subject's health, and do not find allergy and other in experimentation
Adverse reaction.
Claims (3)
1. a kind of blueberry lutein ester pressed candy, it is characterised in that be made of the raw material of following parts by weight:Blueberry freezes
Powder 28-48 parts, lutein ester 10-15 parts, garlic polysaccharide 8-12 parts, Chinese medical extract 10-15 parts, mannitol 20-30 parts, tristearin
Sour magnesium 3-7 parts;
The Chinese medical extract is according to 1 by purslane, lophatherum gracile, Poria cocos and honeysuckle:0.5-1:0.7-0.9:0.4-0.6's
Made from weight ratio.
2. blueberry lutein ester pressed candy according to claim 1, it is characterised in that be by the raw material of following parts by weight
It is manufactured:It is 38 parts of blueberry freeze-dried powder, 13 parts of lutein ester, 10 parts of garlic polysaccharide, 12 parts of Chinese medical extract, 25 parts of mannitol, hard
5 parts of fatty acid magnesium.
3. blueberry lutein ester pressed candy according to claim 1, it is characterised in that the Chinese medical extract is by horse
Bitterroot, lophatherum gracile, Poria cocos and honeysuckle are according to 1:0.7:0.8:Made from 0.5 weight ratio.
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108208815A (en) * | 2018-02-06 | 2018-06-29 | 山东圣海保健品有限公司 | Blueberry and the double-colored composite sheet of lutein ester and preparation method thereof |
CN109938146A (en) * | 2019-03-22 | 2019-06-28 | 西安梵帝罗光学科技有限公司 | A kind of blueberry lutein ester pressed candy and preparation method |
CN110169484A (en) * | 2019-04-23 | 2019-08-27 | 广东润源中天生物科技有限公司 | A kind of blueberry lutein ester pressed candy and preparation method thereof |
CN111227097A (en) * | 2020-02-27 | 2020-06-05 | 山东祥宏堂医药有限公司 | Blueberry lutein ester candy tablet and preparation method thereof |
CN111227231A (en) * | 2020-01-16 | 2020-06-05 | 明眸时代(武汉)生物技术有限公司 | Composite blueberry lutein ester powder and preparation method thereof |
CN111955587A (en) * | 2020-07-29 | 2020-11-20 | 广州长生康生物科技有限公司 | Blueberry lutein ester tabletting candy process |
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CN105580952A (en) * | 2014-10-20 | 2016-05-18 | 威海新异生物科技有限公司 | American ginseng tableting candy production method |
CN106260417A (en) * | 2016-08-09 | 2017-01-04 | 北京斯利安药业有限公司 | A kind of compositions containing phylloxanthin and the pressed candy of preparation thereof |
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CN101006842A (en) * | 2006-01-24 | 2007-08-01 | 抚顺正航食品有限公司 | A Chinese herbal polysaccharide cake |
CN105580952A (en) * | 2014-10-20 | 2016-05-18 | 威海新异生物科技有限公司 | American ginseng tableting candy production method |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN108208815A (en) * | 2018-02-06 | 2018-06-29 | 山东圣海保健品有限公司 | Blueberry and the double-colored composite sheet of lutein ester and preparation method thereof |
CN109938146A (en) * | 2019-03-22 | 2019-06-28 | 西安梵帝罗光学科技有限公司 | A kind of blueberry lutein ester pressed candy and preparation method |
CN110169484A (en) * | 2019-04-23 | 2019-08-27 | 广东润源中天生物科技有限公司 | A kind of blueberry lutein ester pressed candy and preparation method thereof |
CN111227231A (en) * | 2020-01-16 | 2020-06-05 | 明眸时代(武汉)生物技术有限公司 | Composite blueberry lutein ester powder and preparation method thereof |
CN111227097A (en) * | 2020-02-27 | 2020-06-05 | 山东祥宏堂医药有限公司 | Blueberry lutein ester candy tablet and preparation method thereof |
CN111955587A (en) * | 2020-07-29 | 2020-11-20 | 广州长生康生物科技有限公司 | Blueberry lutein ester tabletting candy process |
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