CN107375815A - A kind of Chinese medicine for treating tumor in digestive tract - Google Patents
A kind of Chinese medicine for treating tumor in digestive tract Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/24—Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/8888—Pinellia
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Abstract
The present invention relates to the field of Chinese medicines:Particularly a kind of Chinese medicine for treating tumor in digestive tract.For the deficiency of the Chinese traditional treatment tumour of prior art:So as to propose a kind of method of new treatment tumour;The growth of tumour can be effectively controlled, it, which solves the technical scheme of problem, is:There are following parts by weight:0.01 0.03 parts of the dried venom of toads, 56 parts of scorpio, 9 15 parts of the tuber of pinellia, 35 parts of excrementum pteropi (wine is ground), 8 10 parts of the bighead atractylodes rhizome, 23 parts of dried orange peel, 23 parts of fructus amomi, 23 parts of the banksia rose, 8 10 parts of rhizoma cyperi, 57 parts of Fructus meliae toosendan, 68 parts of cattail pollen (stir-frying), 12 15 parts of fritillaria thunbergii, 68 parts of radix glehniae, 10 12 parts of Radix Angelicae Sinensis, 10 12 parts of radix rehmanniae recen, 45 parts of radix glycyrrhizae are made.Toxic side effect of the present invention is small, and treatment is convenient, and medical expense is low, and when reaching same curative effect, its treatment cost is only chemotherapy, 1st/50th to ten of operation.
Description
Technical field
The present invention relates to the field of Chinese medicines:After particularly a kind of iatrotechnics or chemotherapy metenteron tumour Chinese medicine.
Background technology
Tumor in digestive tract (cancer of the esophagus, cardiac cancer, stomach cancer, duodenal cancer, cholangiocarcinoma, appendix cancer, colon ascendens cancer, horizontal knot
Intestinal cancer, carcinoma of descending colon, carcinoma of sigmoid, the carcinoma of the rectum), chemotherapeutics can not prevent from recurring and shifting, and prevent from recurring and shift master
The immunity of itself is leaned on, chemotherapeutics is to reduce the immunity of itself, and chemotherapeutics is difficult treatment tumour, and many patients exist
The faint exacerbation of constitution between chemotherapy stage, it is difficult to continue, only interrupt treatment.Motherland's medical science thinks the morbidity of tumour, is
In vivo and in vitro under the influence of various factors, organism balance is lacked of proper care, zang-fu differentiation dysfunction, anti-cancer function it is low and caused by
The pent-up accumulation of gas, blood, phlegm, food forms.
Motherland's medical science is broadly divided into two aspects of internal cause and external cause to the understanding of tumor invasion reason.Internal cause refers to human body gas
Anemia is empty, and seven feelings are too and internal organs qi and blood malfunction, external cause refer to evil poison and invaded, and accumulate poly- channels and collaterals, internal organs, and cause the stagnation of the circulation of vital energy, blood stasis,
Phlegm coagulates, caused by dyspepsia etc..
But exopathogen people invades must be not normal in function, when vital qi consumes, the beginning can avail oneself of the opportunity to get in, and then develop into sufferer,
Such as《Huatuo's Zhongzang classic》Say;" Ji Ju Disorder lumps in the abdomen, all vital organs of the human body vital qi lose and perverse trend simultaneously, be then it is raw here.”
《The General Treatise on the Cause and Symptoms of Diseases》Also cloud:" Disorder lump in the abdomen persons, all uncomfortable by cold-dampness, indigestion, mutually fight and tie and life with visceral-qi.”
《Required Readings for Medical Professionals》Also note that:" winner of product, positive unsaturated vapor, then perverse trend crouch it." illustrate only in body just
Unsaturated vapor, imbalance of yin and yang, during anti-evil inferior capabilities, exopathogen begins to take advantage of a weak point, just easily occur tumour, that is, " heresy is gathered, its
Gas must be empty ".
Traditional Chinese Medicine thinks that the prosperity and decline of healthy tendency is to determine to form one of important internal factor of tumour, and healthy tendency is abundant, though have
Evil poison invasion also will not be disease, and when weakened body resistance, it is easy to fall ill due to being just unequal to evil.That is " institute of heresy is chilly, and its gas must be empty ",
When " weakened body resistance ", due to being just unequal to heresy, perverse trend is detained, and then makes qi depression to blood stasis, and the solidifying poison of phlegm is poly-, mutually cementing, accumulates Yu Ercheng accumulations,
It is to cause tumour to be formed.As described in Zhang Jiegu:" strong people then has it without product, empty people, and taste are dispelled weak, and qi and blood two declines, thoughts when four,
All can be into product ".So-called " healthy tendency deposit in, heresy can not be done ".
A kind of Chinese medicine composition and its preparation for treating malignant tumor of digestive tract of number of patent application 201610428181.7
Technical scheme is:The composition by following weight than raw material form:Zaocys dhumnade 7-23 parts, coix seed 15-
45 parts, Snakegourd Fruit 7-23 parts, scorpio 2-8 parts, centipede 2-6 parts, the membrane of a chicken's gizzard 5-15 parts, Rhizoma Sparganii 5-15 parts, curcuma zedoary 5-15 parts, sal ammoniac
0.15-0.45 parts, spina gleditsiae 7-23 parts, indigo naturalis 5-15 parts.
Present invention side solves:Coix seed invigorating spleen to remove dampness is with righting gas in side;Simultaneously using Snakegourd Fruit, indigo naturalis, spina gleditsiae with resolving sputum
Removing toxic substances focuses on anticancer, while coix seed dampness removing is leaked with toxin expelling, is monarch drug in a prescription altogether using strengthening vital QI to eliminate pathogenic factors as this;Phlegm-blood stasis coalesces in and hair is
Cancerous swelling, thus minister with sal ammoniac, Rhizoma Sparganii, curcuma zedoary blood-breaking disperse accumulations, softening and resolving hard mass to take stopgap measures;Promoting blood circulation, which focuses on brokenly, to be dissipated, simultaneous to remove obstruction in channels to relieve pain, and can be answered
With Drug Prepared from Insects with search pick it is most wonderful, help with zaocys dhumnade, scorpio, centipede with search wind and removing obstruction in channels easily strengthen blood-breaking disperse accumulations, softening and resolving hard mass it
Work(, because bitter cold medicine and Drug Prepared from Insects are in the majority in all medicines, easily hinder the stagnant spleen of stomach, while in whole therapeutic process, pay attention to caring for shield
Stomach Qi, make with the membrane of a chicken's gizzard with the fortune spleen that helps digestion.All medicine phases are closed, and play invigorating the spleen toxin expelling altogether, softening and resolving hard mass, the effect of searching wind and removing obstruction in channels.This hair
Bright Chinese medicine composition and its preparation is that inventor passes through clinical verification for many years.Selected medicinal material compatibility is suitable, with traditional Chinese medicine
Above-mentioned all medicine phases are matched somebody with somebody to instruct, play the effect of Synergistic by the compatibility theory of monarch so that full side has invigorating the spleen row
Poison, softening and resolving hard mass, the effect of searching wind and removing obstruction in channels.
Number of patent application:A kind of 200510025151.3 Chinese medicine preparation for treating tumor in digestive tract
Technical scheme is:It is prepared with 8 kinds of Chinese medicinal materials of following weight:Radix pseudostellariae 2-8 parts, Radix Angelicae Sinensis 1-5
Part, polyporus lucidus 1-4 parts, sealwort 1-4 parts, Chinese yam rhizome 2-6 parts, bark of eucommia 1-5 parts, oldenlandia diffusa 2^-8 parts, bittersweet 1-6 parts.
All medicine phases are matched somebody with somebody, and taste are good for, and middle Jiao is able to metaplasia essence of water and grain, and kidney essense is filled, and and can benefit helps the foundation of acquired constitution, and qi and blood fills
It is full of, then Healthy energy reises and evil falls.So as to improve body's immunity, promote the good health and a long life of human body, enhance life and life quality.
Chinese medicine preparation of the present invention is used to treat tumor in digestive tract and tumor in digestive tract Radiotherapy chemotherapy patient, has invigorating the spleen kidney, fills out
Marrow, replenishing qi and blood, clear addiction heat, the effect of the tired product that disappears, righting gas.The pharmacodynamic study of Chinese medicine preparation of the present invention also demonstrates that it has and dispelled
Heresy, righting, synergy, attenuation.Clinical practice proves that the medicine is safely, effectively.
Number of patent application:201010130786.0 treat the righting removing summer-heat Chinese medicine of tumor in digestive tract
Technical scheme is:It is mainly made up of following a few taste bulk drugs by following weight proportions:Radix Astragali 15-45 parts, glossy privet
Sub- 15-45 parts, selfheal 15-45 parts, oldenlandia diffusa 15-45 parts.
The advantage of the invention is that:Righting removing summer-heat Chinese medicine of the present invention mainly chooses the Radix Astragali, the fruit of glossy privet, oldenlandia
Grass, the taste Chinese medicine of selfheal four composition, it is that clinical treatment digests the righting Invigorating Qi commonly used into tumour and method of dissipating heat and detoxifying combination,
The effect of certain is obtained in preclinical application.On this basis, applicant further found that adding on the basis of above-mentioned four tastes Chinese medicine
Upper " ganoderma lucidum, Chinese yam " two taste Chinese medicine, curative effect is more excellent, and while with clearing heat and detoxicating medicine, the training for paying attention to qi and blood again is mended, and residence is logical
In bowl spares, there is treating a disease by looking into both its root cause and symptoms, the characteristics of tonification and purgation in combination.
Tumour Chinese traditional treatment method more than can be seen that:All it is the General Principle according to the traditional Chinese medical science:Malignant tumor patient
Extremely feeble state is presented in late period more.So it is defined as asthenic symptoms when dialectical more, and asthenic symptoms are treated with regard to qi-restoratives.Righting is followed to consolidate more
This, strengthens immunologic function, and toxic removing drives away the basic theories that tumour is the effective measures of anti-curing oncoma for mark.But inventor is led to
Long-term clinical observation is crossed to find:This analysis judges the reality for not necessarily meeting tumour, in the basic cause of disease, the interpretation of the cause, onset and process of an illness, the state of an illness
Aspect, excessively it is conceived to symptom performance.Do not solve reason and essential problem, this weak phenomenon and result are to be difficult to obtain root
This control.To treating malignant tumor, if improper with reinforcing method, Expected Results can not be not only received, the state of an illness can be increased on the contrary
Seriousness.Tumour is the cell of itself mutation, is not external composition.Tonic can not only subsidize normal cell, Er Qieneng
The tumour cell of mutation is subsidized, because growth of tumour cell is fast, it seem likely that tonic can more effectively be utilized than normal cell.
In the event of such case, then the state of an illness of malignant tumour cannot not only control, and can also encourage its growth, so that the state of an illness
Deteriorate.
The content of the invention
For the deficiency of the Chinese traditional treatment tumour of prior art:The present invention is from clinical research;Draw:Malignant tumour,
For vicious disease, vicious how miserable rapid, few simple asthenic symptoms of causing a disease.Virtual image is only a kind of result, is not essence
And reason.So as to propose a kind of method of new treatment tumour;The growth of tumour can be effectively controlled, it solves the technology of problem
Scheme is:
A kind of Chinese medicine for treating tumor in digestive tract:There are following parts by weight:
It is dried venom of toads 0.01-0.03 parts, scorpio 5-6 parts, tuber of pinellia 9-15 parts, excrementum pteropi (wine is ground) 3-5 parts, bighead atractylodes rhizome 8-10 parts, old
Skin 2-3 parts, fructus amomi 2-3 parts, banksia rose 2-3 parts, rhizoma cyperi 8-10 parts, Fructus meliae toosendan 5-7 parts, cattail pollen (stir-fry) 6-8 parts, fritillaria thunbergii 12-
15 parts, radix glehniae 6-8 parts, Radix Angelicae Sinensis 10-12 parts, radix rehmanniae recen 10-12 parts, radix glycyrrhizae 4-5 parts is made.
Preferably:Dried venom of toads 0.02-0.03 parts, scorpio 5.5-6 parts, tuber of pinellia 12-15 parts, excrementum pteropi (wine is ground) 4-5 parts, the bighead atractylodes rhizome
9-10 parts, dried orange peel 2.5-3 parts, fructus amomi 2.5-3 parts, banksia rose 2.5-3 parts, rhizoma cyperi 9-10 parts, Fructus meliae toosendan 6-7 parts, cattail pollen (stir-frying)
7-8 parts, fritillaria thunbergii 13-15 parts, radix glehniae 7-8 parts, Radix Angelicae Sinensis 11-12 parts, radix rehmanniae recen 11-12 parts, radix glycyrrhizae 4.5-5 parts are made.
More preferably:It is 0.03 part of the dried venom of toads, 6 parts of scorpio, 15 parts of the tuber of pinellia, 5 parts of excrementum pteropi (wine is ground), 10 parts of the bighead atractylodes rhizome, old
3 parts of skin, 3 parts of fructus amomi, 3 parts of the banksia rose, 10 parts of rhizoma cyperi, 7 parts of Fructus meliae toosendan, 8 parts of cattail pollen (stir-frying), 15 parts of fritillaria thunbergii, 8 parts of radix glehniae,
12 parts of Radix Angelicae Sinensis, 12 parts of radix rehmanniae recen, 5 parts of radix glycyrrhizae are made.
Plurality of Chinese formulation can be made in the present invention, and Chinese medicinal material active ingredient and the pharmaceutical carrier of Chinese medicine preparation are pressed arbitrarily
Ratio forms, and it can be 0.1-99.9% that wherein active ingredient, which accounts for weight ratio, and it can be 99.9- that pharmaceutical carrier, which accounts for weight ratio,
0.1%.Pharmaceutical carrier can be starch, dextrin, protein sugar, sugarcane ward off, superfine silica gel powder, refined honey or other common carriers.
Decoction preparation method is:
1):Weighed by above-mentioned formula:Excrementum pteropi (wine is ground), the bighead atractylodes rhizome, radix glehniae, radix glycyrrhizae, the water intense fire of 2 times of weight of addition burn
Open to change and be cooked by slow fire 20 minutes, then add dried orange peel, the banksia rose, rhizoma cyperi, cattail pollen (stir-frying) mixing decoct and filter to obtain filtrate in 10 minutes;
2):Weigh scorpio, the tuber of pinellia, fructus amomi, Fructus meliae toosendan, fritillaria thunbergii, Radix Angelicae Sinensis, radix rehmanniae recen, the water for adding 2 times of weight, intense fire
Boiled change is cooked by slow fire filtration in 30 minutes, merges secondary concoction, stands 24 hours, take supernatant, add the dried venom of toads of corresponding weight
Fine powder both may be used.
Process for producing granula is:
1):Weighed by above-mentioned formula:Excrementum pteropi (wine is ground), the bighead atractylodes rhizome, radix glehniae, radix glycyrrhizae, the water intense fire of 2 times of weight of addition burn
Open to change and be cooked by slow fire 20 minutes, then add dried orange peel, the banksia rose, rhizoma cyperi, cattail pollen (stir-frying) mixing decoct and filter to obtain filtrate in 10 minutes;
2):Weigh scorpio, the tuber of pinellia, fructus amomi, Fructus meliae toosendan, fritillaria thunbergii, Radix Angelicae Sinensis, radix rehmanniae recen, the water for adding 2 times of weight, intense fire
Boiled change is cooked by slow fire filtration in 30 minutes, merges secondary concoction, stands 24 hours, take supernatant, add the dried venom of toads of corresponding weight
Fine powder is condensed into relative density 1.35 or so (80 DEG C of heat are surveyed) thick medicinal extract, is dried in vacuo, crushes, add appropriate pharmaceutical carrier and mix
It is even, the granulation of 75% alcohol, dry, pack and produce.
Wherein:
Weakness of the spleen and the stomach serious addition Radix Astragali 15-20 parts, Chinese yam 20-30 parts;
Qi stagnation blood stasis seriously add root tuber of aromatic turmeric 5-8 parts, red sage root 10-15 parts;
The deficiency of liver-yin and kidney-yin seriously adds fruit of glossy privet 15-20 parts, American Ginseng 10-12 parts.
Applicant is drawn by clinical research:Malignant tumour, initial stage, state of an illness performance was light shallow, but its essence has been extremely
It is serious.To middle and advanced stage, because the growth of tumour makes body depleted, this just shows the extremely empty state to decline.This
From light to heavy, by being all the vicious dominating role leading by tumour in the empty overall process of actual arrival.In whole Disease evolution,
Vicious to be on the rise, vital essence is taken by force, and perverse trend is increasingly flourishing, or even can not be contained, now weakened body resistance vicious more to contain.To pernicious swollen
On the actual situation sample of knurl judges, specify it is vicious it is flourishing for this, constitution void declines for mark, and it is because physically weak is fruit, directs at and vicious is that poison, which is contained,
The essence of disease.The virtual image of malignant tumour, it is not this void of constitution, but the result of vicious infringement.Further also have as tumour is disliked
Poison diffuses tension and relaxation, and constitution void declines also to be aggravated therewith.All the time all there is the problem of vicious flourishing in malignant tumour, this is malignant tumour
Leading factor.The malignant tumour state of an illness can be made to be effectively controlled, can depend entirely on effectively suppress vicious development.Just
Due to this, treatment malignant tumour is adhered to attack based on poison all the time.
The present invention emphasizes to attack based on poison all the time:
One, to attack emphasize that malignant tumour will be implemented all the time by attacking malicious therapy, can not loosen because having a delicate constitution based on poison
Or stop attacking malicious treatment.
Secondly, to attack emphasize based on poison to be used as routine and base therapy rule to attack poison, definitely do not oppose qi-restoratives, be
Can not be normal based on qi-restoratives, qi-restoratives can only be handled some specific questions occurred in the course of disease as interim.
Malignant disease knot gathers in interior, rushes down malicious Toxin-Vanquishing with medicine for oral administration, vicious sensible in outer, to dissipate poison from externally applied drug detoxification.
According to this principle, the present invention can take orally while external plaster can be made, using external plaster:By reaching outside
It is interior, swelling and pain relieving, stagnation resolvation of detoxifying, solve pain and swelling.
Drug therapy tumour of the present invention is compared with Western medicine chemotherapy:
1st, toxic side effect is small, almost without bone marrow suppression, the heart, liver, kidney, gastrointestinal lesions;
2nd, there is certain therapeutic effect, and majority is the end-stage patients that Western medicine can not treat;
3rd, treatment is convenient, and based on oral medicine, while external application sticks majority and is not required to be in hospital, and outpatient service can treat;
4th, medical expense is low, and when reaching same curative effect, its treatment cost is only chemotherapy, 1st/50th to ten of operation.
Embodiment
The content of invention is further detailed with reference to embodiments:
Embodiment one
A kind of Chinese medicine for treating tumor in digestive tract:There are following parts by weight:
0.01 part of the dried venom of toads, 5 parts of scorpio, 9 parts of the tuber of pinellia, 3 parts of excrementum pteropi (wine is ground), 8 parts of the bighead atractylodes rhizome, 2 parts of dried orange peel, 2 parts of fructus amomi, wood
Fragrant 2 parts, 8 parts of rhizoma cyperi, 5 parts of Fructus meliae toosendan, 6 parts of cattail pollen (stir-frying), 12 parts of fritillaria thunbergii, 6 parts of radix glehniae, 10 parts of Radix Angelicae Sinensis, radix rehmanniae recen 10
Part, 4 parts of radix glycyrrhizae are made.
Decoction preparation method is:
1):Weighed by above-mentioned formula:Excrementum pteropi (wine is ground), the bighead atractylodes rhizome, radix glehniae, radix glycyrrhizae, the water intense fire of 2 times of weight of addition burn
Open to change and be cooked by slow fire 20 minutes, then add dried orange peel, the banksia rose, rhizoma cyperi, cattail pollen (stir-frying) mixing decoct and filter to obtain filtrate in 10 minutes;
2):Weigh scorpio, the tuber of pinellia, fructus amomi, Fructus meliae toosendan, fritillaria thunbergii, Radix Angelicae Sinensis, radix rehmanniae recen, the water for adding 2 times of weight, intense fire
Boiled change is cooked by slow fire filtration in 30 minutes, merges secondary concoction, stands 24 hours, take supernatant, add the dried venom of toads of corresponding weight
Fine powder both may be used.
Embodiment two
A kind of Chinese medicine for treating tumor in digestive tract:There are following parts by weight:
Preferably:0.02 part of the dried venom of toads, 5.5 parts of scorpio, 12 parts of the tuber of pinellia, 4 parts of excrementum pteropi (wine is ground), 9 parts of the bighead atractylodes rhizome, dried orange peel 2.5
Part, 2.5 parts of fructus amomi, 2.5 parts of the banksia rose, 9 parts of rhizoma cyperi, 6 parts of Fructus meliae toosendan, 7 parts of cattail pollen (stir-frying), 13 parts of fritillaria thunbergii, 7 parts of radix glehniae,
11 parts of Radix Angelicae Sinensis, 11 parts of radix rehmanniae recen, 4.5 parts of radix glycyrrhizae are made.
Decoction preparation method is:
1):Weighed by above-mentioned formula:Excrementum pteropi (wine is ground), the bighead atractylodes rhizome, radix glehniae, radix glycyrrhizae, the water intense fire of 2 times of weight of addition burn
Open to change and be cooked by slow fire 20 minutes, then add dried orange peel, the banksia rose, rhizoma cyperi, cattail pollen (stir-frying) mixing decoct and filter to obtain filtrate in 10 minutes;
2):Weigh scorpio, the tuber of pinellia, fructus amomi, Fructus meliae toosendan, fritillaria thunbergii, Radix Angelicae Sinensis, radix rehmanniae recen, the water for adding 2 times of weight, intense fire
Boiled change is cooked by slow fire filtration in 30 minutes, merges secondary concoction, stands 24 hours, take supernatant, add the dried venom of toads of corresponding weight
Fine powder both may be used.
Embodiment three
A kind of Chinese medicine for treating tumor in digestive tract:There are following parts by weight:
0.03 part of the dried venom of toads, 6 parts of scorpio, 15 parts of the tuber of pinellia, 5 parts of excrementum pteropi (wine is ground), 10 parts of the bighead atractylodes rhizome, 3 parts of dried orange peel, 3 parts of fructus amomi,
3 parts of the banksia rose, 10 parts of rhizoma cyperi, 7 parts of Fructus meliae toosendan, 8 parts of cattail pollen (stir-frying), 15 parts of fritillaria thunbergii, 8 parts of radix glehniae, 12 parts of Radix Angelicae Sinensis, radix rehmanniae recen
12 parts, 5 parts of radix glycyrrhizae is made.
Decoction preparation method is:
1):Weighed by above-mentioned formula:Excrementum pteropi (wine is ground), the bighead atractylodes rhizome, radix glehniae, radix glycyrrhizae, the water intense fire of 2 times of weight of addition burn
Open to change and be cooked by slow fire 20 minutes, then add dried orange peel, the banksia rose, rhizoma cyperi, cattail pollen (stir-frying) mixing decoct and filter to obtain filtrate in 10 minutes;
2):Weigh scorpio, the tuber of pinellia, fructus amomi, Fructus meliae toosendan, fritillaria thunbergii, Radix Angelicae Sinensis, radix rehmanniae recen, the water for adding 2 times of weight, intense fire
Boiled change is cooked by slow fire filtration in 30 minutes, merges secondary concoction, stands 24 hours, take supernatant, add the dried venom of toads of corresponding weight
Fine powder both may be used.
Example IV
A kind of Chinese medicine for treating tumor in digestive tract:There are following parts by weight:
0.03 part of the dried venom of toads, 6 parts of scorpio, 15 parts of the tuber of pinellia, 5 parts of excrementum pteropi (wine is ground), 10 parts of the bighead atractylodes rhizome, 3 parts of dried orange peel, 3 parts of fructus amomi,
3 parts of the banksia rose, 10 parts of rhizoma cyperi, 7 parts of Fructus meliae toosendan, 8 parts of cattail pollen (stir-frying), 15 parts of fritillaria thunbergii, 8 parts of radix glehniae, 12 parts of Radix Angelicae Sinensis, radix rehmanniae recen
12 parts, 5 parts of radix glycyrrhizae, 20 parts of the Radix Astragali, 30 parts of Chinese yam be made.
Decoction preparation method is:
1):Weighed by above-mentioned formula:Excrementum pteropi (wine is ground), the bighead atractylodes rhizome, radix glehniae, radix glycyrrhizae, the water of the Radix Astragali 2 times of weight of addition are military
Baked wheaten cake is opened to change and is cooked by slow fire 20 minutes, then is added dried orange peel, the banksia rose, rhizoma cyperi, cattail pollen (stir-frying) and mixed decoction and filter and must filter for 10 minutes
Liquid;
2):Scorpio, the tuber of pinellia, fructus amomi, Fructus meliae toosendan, fritillaria thunbergii, Radix Angelicae Sinensis, radix rehmanniae recen, the water of Chinese yam 2 times of weight of addition are weighed,
Boiled change of intense fire is cooked by slow fire filtration in 30 minutes, merges secondary concoction, stands 24 hours, take supernatant, add corresponding weight
Dried venom of toads fine powder both may be used.
Embodiment five
A kind of Chinese medicine for treating tumor in digestive tract:There are following parts by weight:
0.03 part of the dried venom of toads, 6 parts of scorpio, 15 parts of the tuber of pinellia, 5 parts of excrementum pteropi (wine is ground), 10 parts of the bighead atractylodes rhizome, 3 parts of dried orange peel, 3 parts of fructus amomi,
3 parts of the banksia rose, 10 parts of rhizoma cyperi, 7 parts of Fructus meliae toosendan, 8 parts of cattail pollen (stir-frying), 15 parts of fritillaria thunbergii, 8 parts of radix glehniae, 12 parts of Radix Angelicae Sinensis, radix rehmanniae recen
12 parts, 5 parts of radix glycyrrhizae, 8 parts of root tuber of aromatic turmeric, 15 parts of the red sage root be made.
Process for producing granula is:
1):Weighed by above-mentioned formula:Excrementum pteropi (wine is ground), the bighead atractylodes rhizome, radix glehniae, radix glycyrrhizae, the water of the Radix Astragali 2 times of weight of addition are military
Baked wheaten cake is opened to change and is cooked by slow fire 20 minutes, then is added dried orange peel, the banksia rose, rhizoma cyperi, cattail pollen (stir-frying) and mixed decoction and filter and must filter for 10 minutes
Liquid;
2):Weigh scorpio, the tuber of pinellia, fructus amomi, Fructus meliae toosendan, fritillaria thunbergii, Radix Angelicae Sinensis, radix rehmanniae recen, root tuber of aromatic turmeric, the red sage root, Chinese yam addition weight
The water of 2 times of amount, boiled change of intense fire are cooked by slow fire filtration in 30 minutes, merge secondary concoction, stand 24 hours, take supernatant, add
The dried venom of toads fine powder of corresponding weight is condensed into relative density 1.35 or so (80 DEG C of heat are surveyed) thick medicinal extract, is dried in vacuo, crushes, adds suitable
Measure pharmaceutical carrier to mix, the granulation of 75% alcohol, dry, pack and produce.
Embodiment six
A kind of Chinese medicine for treating tumor in digestive tract:There are following parts by weight:
0.03 part of the dried venom of toads, 6 parts of scorpio, 15 parts of the tuber of pinellia, 5 parts of excrementum pteropi (wine is ground), 10 parts of the bighead atractylodes rhizome, 3 parts of dried orange peel, 3 parts of fructus amomi,
3 parts of the banksia rose, 10 parts of rhizoma cyperi, 7 parts of Fructus meliae toosendan, 8 parts of cattail pollen (stir-frying), 15 parts of fritillaria thunbergii, 8 parts of radix glehniae, 12 parts of Radix Angelicae Sinensis, radix rehmanniae recen
12 parts, 5 parts of radix glycyrrhizae, 20 parts of the fruit of glossy privet, 12 parts of American Ginseng be made.
Process for producing granula is:
1):Weighed by above-mentioned formula:Excrementum pteropi (wine is ground), the bighead atractylodes rhizome, radix glehniae, American Ginseng, radix glycyrrhizae, Radix Astragali addition weight 2
Boiled change of water intense fire again is cooked by slow fire 20 minutes, then adds dried orange peel, the banksia rose, rhizoma cyperi, cattail pollen (stir-frying) and mix decoction 10 minutes
Filter to obtain filtrate;
2):Weigh scorpio, the tuber of pinellia, fructus amomi, Fructus meliae toosendan, fritillaria thunbergii, Radix Angelicae Sinensis, radix rehmanniae recen, the fruit of glossy privet, Chinese yam addition weight 2
Water again, boiled change of intense fire are cooked by slow fire filtration in 30 minutes, merge secondary concoction, stand 24 hours, take supernatant, addition is accordingly
The dried venom of toads fine powder of weight is condensed into relative density 1.35 or so (80 DEG C of heat are surveyed) thick medicinal extract, is dried in vacuo, crushes, add appropriate medicine
Mixed with carrier, the granulation of 75% alcohol, dry, pack and produce.
Medicine in the present invention:
The dried venom of toads
Nature and flavor:Acrid flavour, it is warm-natured;It is poisonous;
Channel tropism:Thoughts of returning home warp;
Effect:With removing toxic substances, analgesic, the effect of inducing resuscitation of having one's ideas straightened out.
Scorpio
Nature and flavor:It is pungent, put down;
Channel tropism:Return liver warp;
Effect:Relieving convulsion and spasm, detoxicating and resolving a mass, remove obstruction in channels to relieve pain;
Cure mainly:For anxious chronic infantile convulsion, facial paralysis, lockjaw, sore swell and ache curative, scrofula tuberculosis, migraine and general headache, rheumatism numbness
Bitterly.
Fructus amomi
Nature and flavor:It is pungent, temperature;
Channel tropism:Returns spleen, stomach;
Effect:Dampness elimination, promoting the circulation of qi, middle benefit gas are antiabortive;
Cure mainly:For retention of damp leading to blockage of QI, abdominal distention, poor appetite, cold-dampness diarrhea, pernicious vomiting, fetal irritability.
The bighead atractylodes rhizome
Nature and flavor:It is bitter, sweet, temperature;
Channel tropism:Returns spleen, stomach;
Effect:Air making-up and spleen enlivening, eliminate dampness and have diuretic effect, hidroschesis are antiabortive;
Cure mainly:For deficiency-weakness of spleen-QI, anorexia and loose stool, phlegm and retained fluid oedema, exterior deficiency spontaneous perspiration, fetal irritability.
Dried orange peel
Nature and flavor:Acrid flavour, hardship, it is warm-natured;
Channel tropism:Returns spleen, stomach, lung channel;
Effect:Qi-regulating is with, eliminating dampness and eliminating phlegm, sharp water defaecation;
Cure mainly:It is incoordination between the spleen and the stomach, abdominal distention, do not feel like eating, hiccup is vomitted, phlegm-damp obstructing lung, coughing with a lot of sputum, chest diaphragm is full vexed,
Vertigo, oedema, difficult urination, constipation, acute mastitis sore tinea, middle ichthyophagy crab poison, wine poison.
The banksia rose
Nature and flavor:It is pungent, bitter, temperature;
Channel tropism:Returns spleen, stomach, large intestine, gallbladder channel;
Effect:Promoting qi circulation and relieving pain, declare in tune stagnant;
Cure mainly:For abdominal distention, weight after rush down dysentery, spleen eating less, hypochondriac pain, jaundice.
Rhizoma cyperi
Nature and flavor:It is mild-natured, acrid flavour, mildly bitter flavor, taste micro-sweet;
Channel tropism:Enter Liver Channel;
Effect:Dispersing stagnated hepatoqi, menstruction regulating and pain relieving;
Cure mainly:For pain over the hypochondriac region, abdominal distention, hernia pain, irregular menstruation, swollen breasts.
Fructus meliae toosendan
Nature and flavor:Hardship, tremble with fear slightly poisonous;
Channel tropism:Return liver, stomach, small intestine, bladder warp;
Effect:Promoting qi circulation and relieving pain, desinsection;
Cure mainly:For pain over the hypochondriac region, epigastric pain, hernia pain, abdominal pain due to enterositosis, favus of the scalp, can desinsection, and can analgesic.
Cattail pollen
Nature and flavor:It is sweet, put down;
Channel tropism:Return liver, pericardium channel;
Effect:Hemostasis, stagnation resolvation is treating stranguria;
Cure mainly:For spitting blood, bleeding from five sense organs or subcutaneous tissue, hematuria, uterine bleeding, trusted subordinate's pain, postpartum stasis caused pain, blood strangury and dry pain.
Excrementum pteropi
Nature and flavor:It is bitter, sweet, temperature;
Channel tropism:Return liver warp;
Effect:Promoting blood circulation and stopping pain, removing blood stasis and hemostasis;
Cure mainly:For Amenorrhea, dysmenorrhoea, postpartum stasis, chest and abdomen pain, uterine bleeding, menorrhalgia.
Fritillaria thunbergii
Nature and flavor:Hardship, tremble with fear;
Channel tropism:Return lung, the heart channel of Hang-Shaoyin;
Effect:Preventing phlegm from forming and stopping coughing, heat-clearing dissipating bind;
Cure mainly:For cough with lung heat, deficiency of Yin cough caused by dryness, carbuncle swells, scrofula.
The tuber of pinellia
Nature and flavor:It is pungent, temperature;
Channel tropism:Returns spleen, stomach, lung channel;
Effect:It is eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass;
Cure mainly:For damp-phlegm syndrome, anemophlegmatic vertigo, phlegm and headache, vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hysteriocus, goiter and tumor phlegm
Core, swollen ulcer drug.
The root of straight ladybell
Nature and flavor:It is sweet, it is slightly cold;
Channel tropism:Returns spleen, lung channel;
Effect:Clearing lung and nourishing yin, reinforcing stomach reg fluid;
Cure mainly:For lung-heat type cough, deficiency of Yin overstrain cough, injury thirst.
Radix Angelicae Sinensis
Nature and flavor:Sweet, acrid, warm;
Channel tropism:Return liver, the heart, the spleen channel;
Effect:Promoting blood circulation and stopping pain, tonifying blood and regulating menstruation, relax bowel;
Cure mainly:For dizziness due to deficiency of blood, irregular menstruation, Amenorrhea, dysmenorrhoea, sallow complexion, asthenia cold abdominalgia, traumatic injury, rheumatism
Numbness pain, ulcer sores, dry constipation of intestines.
Radix rehmanniae recen
Nature and flavor:It is sweet, bitter, tremble with fear;
Channel tropism:The thoughts of returning home, liver and kidney channel;
Effect:Clearing heat and cooling blood, nourishing Yin and promoting production of body fluid;
Cure mainly:For Vexed, tongue is deep red, blood-head tells nosebleed, atropurpureus macula, consumption of YIN caused by febrile disease, drink of quenching one's thirst more.
Radix glycyrrhizae
Nature and flavor:It is sweet, put down;
Channel tropism:The thoughts of returning home, spleen, lung, stomach;
Effect:Invigorate the spleen and benefit qi, moisten the lung and relieve the cough, it is clearing heat and detoxicating, alleviate analgesic, relax the property of medicine;
Cure mainly:For weakness of the spleen and the stomach, shortness of breath and fatigue, palpitation and severe palpitation, cough phlegm is few, pathopyretic ulcer, medicine food poisoning, and gastral cavity abdomen is anxious
Bitterly, four limbs contraction pain.
The traditional Chinese medical science treats, and is particular about and is fundamentally treated, in the etiology and pathogenesis of malignant tumour, disease property is all the time
Contained for poison, and in the state of an illness constitution status of patient, disease property belongs to extremely empty again.
Malignant tumour from the beginning of the big void of the not empty healthy tendency to middle and advanced stage of healthy tendency, healthy tendency is under the infringement of perverse trend, by not empty
It can't bear to weakness.The constitution of weakness is restored, must effectively be attacked poison." Xie Quze Zhengan County, heresy do not go to mend foot
As a means of bandit ".
Find that vicious is mostly phlegm by long-term clinical research, caused by extravasated blood, and phlegm, it is to be formed by body fluid cohesion change,
Body fluid normally defeated cloth can not be run, then gather and form phlegm.Phlegm can be with air-flow row, nowhere less than ancients think " stupid phlegm gives birth to all kinds of diseases and ailments ".
Blood comes from middle Jiao, by essence of water and grain institute metaplasia, i.e., it is so-called " middle Jiao, which is bullied, takes juice, change and it is red be meaning blood ".Gas is
Blood is handsome, and blood is with gas row, the stagnation of the circulation of vital energy then blood clotting.
The present invention is detoxified with the dried venom of toads, is relieved pain, inducing resuscitation of having one's ideas straightened out;Tuber of pinellia returns spleen passes through, it is pungent dissipate disappear ruffian and can dry spleen it is wet with except raw phlegm
Source, excrementum pteropi;It is logical that hardship lets out temperature, can promoting blood circulation, removing blood stasis and relieving pain be altogether monarch drug in a prescription eliminating the phlegm, stagnation resolvation, heat-clearing mass dissipating and swelling eliminating;
Cattail pollen is sweet to delay not high, mild-natured, promoting blood circulation and removing blood stasis, inducing diuresis for treating strangurtia, and Radix Angelicae Sinensis is both apt to enrich blood, is apt to promoting blood circulation and stopping pain again, can help
Healthy tendency, again can activating blood circulation and reducing swelling relieve pain two medicines share help excrementum pteropi promoting blood circulation, removing blood stasis and relieving pain;The property of fritillaria thunbergii bitter cold is compared with same with the root of straight ladybell by force
With clearing heat and eliminating phlegm opens strongly fragrant dissipating bind and helps the dry spleen of the tuber of pinellia wet with except the source of producing phlegm is altogether for ministerial drug;
Spleen is the congenital foundation, main qi and blood literization, stomach receiving food and drink, main logical drop, is reduced to harmony.Long-term use of bitter and cold medicines heat-clearing solution
Poison, easy impairment of yang gas, injure one's stomach gas, causes bitter cold to be upset one's stomach and aggravates symptom, makes under patient's appetite day, influences wholistic therapy.In diagnosis and treatment
It is middle to care for shield stomach Qi, the sweet temperature of the bighead atractylodes rhizome, the bighead atractylodes rhizome and dried orange peel with using, can air making-up and spleen enlivening, again can eliminate dampness and have diuretic effect, and taste, eliminating dampness is evil, disappears
Turgor, in the tune that replenishes qi to invigorate the spleen;It is same with eliminating dampness and eliminating phlegm with the tuber of pinellia.Fructus amomi pungent-warm gas is fragrant, and dampness elimination is amusing, relieving QI stagnancy in the stomach, with the bighead atractylodes rhizome, wood
The product of fragrant tonifying spleen promoting the circulation of qi are to control it, the banksia rose, dried orange peel, and stagnant, promoting qi circulation and relieving pain is declared in tune;Gan Wen is equipped with, cares for shield taste.With strong spleen
Stomach, helping taste to rise, clear, drop is turbid.It is gentle with tonifying spleen stomach-Yin deficiency, slowly work, not impairment of the spleen sun, it is cloudy not damage spleen.
Gas is the base substance of human life activity, and promote the various physiological functions of body power, i.e., it is so-called " people it
Have life, rely this gas entirely " enter Liver Channel catharsis liver heat, heat-clearing promoting qi circulation and relieving pain, dispersing stagnated hepatoqi, menstruction regulating and pain relieving with Fructus meliae toosendan with rhizoma cyperi;
Pathogen usually intruding into collateral in protracted disease, enter Liver Channel with scorpio, property is apt to walk to alter, removing toxic substances and dissipating bind, remove obstruction in channels to relieve pain;Longization of becoming silted up heat, heat consuming body fluid,
Body fluid deficiency life poison, enters stomach with radix rehmanniae recen compatibility the root of straight ladybell, is apt to clear ying blood and divides heat evil, nourishing Yin and promoting production of body fluid, reinforcing stomach reg fluid is adjutant altogether.
Radix glycyrrhizae can invigorate the spleen and benefit qi, both be apt to removing toxic substances, again can heat-clearing can be acted on relieving spasm to stop pain, also tool relax the property of medicine, reconcile
The work(of all medicines is to make medicine.
The present invention chooses medicine by long-term clinical and substantial amounts of source investigation from numerous Chinese medicine and obtained well
Effect,
The present invention by it is similar the effect of medicine replacement study Comparison of clinical effect, it is found that the present invention in the dried venom of toads, toad
Shortcake, scorpio, the tuber of pinellia, excrementum pteropi (wine is ground) are indispensable;Inventor once replaced the scorpio clinical discovery present invention clinical with centipede
Treatment works slowly, and treatment cycle lengthens, and replaces the tuber of pinellia to be deteriorated hiccup caused by tumor in digestive tract, abundant expectoration effect with Southern Star, south
Star and the tuber of pinellia share that therapeutic action is not strengthened and the adverse reaction such as dizziness occurs now and then, and addition excrementum pteropi (wine is ground) is not afterwards than having
Then work faster, while the symptom effect such as extremity numbness, bedsore is become apparent from, by adding Qi-tonifying drug, stagnation resolvation medicine, heat-clearing
Medicine, body fluid complementing medicine are all the optimal effectiveness reached in long-term clinic by constantly adjusting.
Observation of curative effect
For short term effect up to 75% or so, late result also has nearly 50%.And all taken effect within 3~7 days in medication.
The total of due to weakness of spleen and stomach is 73.5%, and the total of qi stagnation blood stasis type is 78.3%, and liver-kidney yin deficiency is always 50.0%.
" short term effect " refers to:
(1) in 3~7 days, remission or disappearance:Such as pain, numbness, cough, cough of choking, bleeding, intracranial pressure, chest and abdomen
Water, expiratory dyspnea, dysphagia, difficult defecation, lump compressing, local swelling, discharge slough etc. reduce (light), stopping or
Disappear;
(2) patient mental, muscle power increase, can participate in certain manual labor or recreation.
(3) sign is alleviated or disappeared:As lump quality softens, swelling lightens, hydrops amount is reduced, lymph node softens, diminishes
Deng;
(4) auxiliary examination:Lump volume diminishes or disappeared, hydrops is reduced, related antigen index returns drop or recovers normal;
(5) quality of life improves:Sleep improvement, diet, daily life, two just can take care of oneself, in general manual labor can be carried out or
Recreation.
" late result " is:
Refer to the above-mentioned curative effect after treatment and continue 1~2 year even longer time, mass reduction more than half, and can be engaged in certain
Manual labor.Main auxiliary examination index, which has, more than moderate to be changed.
Clinical observation and curative effect
1.1 general information:
Choose the middle and advanced stage alimentary canal treated in The First Affiliated Hospital of Xinxiang Medical University in April, -2016 in May, 2014
Tumor patient 60,26~71 years old age, average (49.7 ± 8.5) year;
Stomach cancer 22, cancer of the esophagus 20, colorectal cancer 18;
Clinical stages:III phase 41, IV phase 19;
Tumour cell parting:Gland cancer 34, squamous carcinoma 14, adenosquamous carcinoma 12.
1.2 method:
Traditional Chinese herbal decoction composition medicine includes:There are following parts by weight:0.03 part of the dried venom of toads, 6 parts of scorpio, 15 parts of the tuber of pinellia, five spirits
5 parts of fat (wine is ground), 10 parts of the bighead atractylodes rhizome, 3 parts of dried orange peel, 3 parts of fructus amomi, 3 parts of the banksia rose, 10 parts of rhizoma cyperi, 7 parts of Fructus meliae toosendan, cattail pollen (stir-frying) 8
Part, 15 parts of fritillaria thunbergii, 8 parts of radix glehniae, 12 parts of Radix Angelicae Sinensis, 12 parts of radix rehmanniae recen, 5 parts of radix glycyrrhizae are made.
Decoction preparation method is:
1):Weighed by above-mentioned formula:Excrementum pteropi (wine is ground), the bighead atractylodes rhizome, radix glehniae, radix glycyrrhizae, the water of the Radix Astragali 2 times of weight of addition are military
Baked wheaten cake is opened to change and is cooked by slow fire 20 minutes, then is added dried orange peel, the banksia rose, rhizoma cyperi, cattail pollen (stir-frying) and mixed decoction and filter and must filter for 10 minutes
Liquid;
2):Scorpio, the tuber of pinellia, fructus amomi, Fructus meliae toosendan, fritillaria thunbergii, Radix Angelicae Sinensis, radix rehmanniae recen, the water of Chinese yam 2 times of weight of addition are weighed,
Boiled change of intense fire is cooked by slow fire filtration in 30 minutes, merges secondary concoction, stands 24 hours, take supernatant, add corresponding weight
Dried venom of toads fine powder both may be used.
1 dose/d, it is decocted in water for oral dose, collecting decoction about 400mL, a point morning and evening warmly takes twice, and 1 month is a course for the treatment of, is commented after 2 months
Valency curative effect.
1.3 observation index:
(1) clinical efficacy:Clinical efficacy is divided into complete incidence graph (CR), (PR), stably (SD), progress (PD) 4 are alleviated in part
Individual grade,
Wherein focus is wholly absent and the time more than 4 weeks was CR;
Focus maximum major diameter and maximum perpendicular footpath are significantly lower than before treatment after being multiplied and reduce degree more than 50% after treatment,
Other focuses are unchanged, more than 4 weeks are PR without new focus time of occurrence;
Focus maximum major diameter and maximum perpendicular footpath reduce degree less than 50% after being multiplied, increase degree is less than 25%, without new
Focus time of occurrence was SD more than 4 weeks;
Focus maximum major diameter and maximum perpendicular footpath be multiplied after with obvious increase before treatment and degree more than 25% or
It is PD to have new focus to occur.Total effective=CR+PR.
(2) changes in immune function:Respectively at taking patient empty stomach peripheric venous blood 3mL before and after treatment, t lymphocyte subset is detected
The change (including CD4+, CD8+, CD4+/CD8+) of group.
(3) quality of life:According to pretherapy and post-treatment Cattell score (KPS) situation of change by quality of life be divided into raising, decline,
Stablize 3 ranks,
Score increase degree compared with before treating is not less than 10 points to improve after wherein treating;
Score reduction degree compared with before treating is not less than 10 points to decline after treatment,
After treatment score before treating relatively be stably between raising and reduction.
1.4 statistical procedures:
Using the data software processing datas of SPSS 17.0, measurement data is represented with (x ± s), is compared and is examined using t, is counted
Data is represented with rate (%), is compared and is examined using x2, with P<0.05 represents that difference is statistically significant.
1.5 clinical test results:
(1) patient clinical curative effect:
Clinical efficacy is counted after observation group's treatment, patient's complete incidence graph has 23.33% after taking this medicine, and part, which is alleviated, to be had
36.66%, for the stable state of an illness up to 33.33%, total effective rate reaches 60.00%.
The clinical efficacy statistical result of table 1
(2) the comparison of the pretherapy and post-treatment t lymphocyte subset group of patient:
CD4+, CD4+/CD8+ significantly raised, statistically significant (P of difference compared with before treating after observation group's treatment<
0.05);CD8+ is reduced compared with before treating after observation group's treatment, but no significant difference (P>0.05), result of the test is shown in
Table 2;
The comparison (x ± s) of the pretherapy and post-treatment t lymphocyte subset group of the patient of table 2
(3) patients ' life quality improves the comparison of degree:
The patients ' life quality of table 3 improves the statistical result of degree
Group | Improve | Decline | It is stable |
Observation group | 27 (45.00%) * | 15 (25.00%) * | 18 (30.00%) * |
After observation group's treatment, quality of life is stable or the Proportion of patients of raising reaches 75.00%, it is seen that medicine of the invention
Preparation can be effectively improved patients ' life quality, and the postoperative disease relapse ratio of patient significantly reduces.
Model case
One 67 years old male patients, go to a doctor for 13 years because having a stomachache, vomitting to the People's Hospital of city, true by upper digestive tract barium meal, B ultrasound
Examine as stomach cancer, row total gastrectomy operative treatment, pathological biopsy turn out to be sdenocarcinoma of stomach immediately.It is postoperative to give chemotherapy, within the next few days in feel
Abdomen is uncomfortable, nausea sense, hardly possible feed, spiritlessness and weakness, soreness and weakness of waist and knees.Have a medical check-up:Body is become thin, lusterless complexion, chronic facies, activity
It is few.The visible operative incision of upper abdomen, healing are good.Pale tongue arteries and veins is thin.Chemotherapy is given simultaneously takes Chinese medicine preparation of the present invention, one time 1
Bag, 2 times a day, remission after treatment 2 weeks, after medication 6 months, patient symptom disappears, and diet is normal, and health recovers good
It is good.
One 53 years old female patients upper abdomen pain more than 10 years repeatedly, are treated repeatedly by " gastric ulcer ", ineffective.Patient because
Upper abdomen pain aggravates, and gasteremphraxis, Nausea and vomiting 3 days, gastrocopy is diagnosed as stomach cancer, in the October 14 in 2014 of Dao cities first
The big portion's surgery excision of the People's Hospital's row stomach, it is postoperative to send pathologic finding report prompting:Lesser curvature poorly differentiated adenocarcinoma, leaching and placenta percreta,
2 pieces of placenta percreta lymph node has cancer metastasis, starts oral chemotherapeutic on October 22nd, 2014, and rear sense has a delicate constitution, and body weight subtracts
Gently, it is difficult to solve urine, especially night receives the symptom such as poor, weak, constipation for very, in Lai our hospital treatment October 30 in 2014,
Chinese medicine preparation of the present invention is given, 2 times a day, one time one bag, feels that the state of mind is good after patient medication, antisecosis, appetite increases
Add, stool and urine is normal, increased weight, and after 3 courses for the treatment of of medication, 2 months are a course for the treatment of, are checked to First People's Hospital, have no different
Often, immunoassay is prompted:Carcinomebryonic antigen is less than 0.5ng/ml, still adheres to treating at present, and appetite increase, sleep, complexion is good,
Increased weight, supreme abdominal pain sense, multiple comprehensive review do not find relapse and metastasis sign.
One 45 years old male patients, in October, 2015 because having a stomach upset, pain, abdominal distension and the stomach headquarters or seat of leading organs of an institute like the Chinese Academy of Sciences touch the big lump of fist,
Matter is hard, and the thing that swells is 6X 13cm, through hospital gastroscope, CT examination, is diagnosed as stomach cancer.On November 23rd, 2015 row resection of gastric carcinoma.Disease
Reason is diagnosed as breaking up in sdenocarcinoma of stomach, and does 2 radiotherapy of chemotherapy 3 times.The residual stomach trouble stove recurrence of gastrocopy in July, 2016, size are
6.1X 4.7cm, and have a stomach-ache, gasteremphraxis, nausea, become thin, the whole body is weak, therefore can not perform the operation again.Carry out the court's treatment in July, 2016,
Give Chinese medicine preparation of the present invention 2 times a day, one time 1 bag, take three months, subjective symptoms is clearly better, increased weight, muscle power it is extensive
It is multiple.Check within 2 6th, 2017, focus is obviously reduced, and size is 4.8X4.6cma gastrocopies on May 26 in 2017, residual stomach
Portion's recurrence stove is wholly absent, and increased weight 8kg, antisecosis, diet is normal, and oneself can normally go to work, and health returns to trouble
Before carninomatosis.
One 60 years old female patients, in December, 2012 because of stomachache, band blood of defecating, tenesmus, weak, medical treatment of becoming thin, instead
Multiple symptomatic treatment is invalid.In August, 2013, through x ray photograph and gastroscopy pathology inspection, is diagnosed as rectal adenocarcinoma, the same year 9 in certain hospital
The moon is in institute's row " radical resection of rectal carcinoma ".Pathologic examination after operation is " rectal adenocarcinoma III phases ".It is postoperative to receive the combination of Chinese tradiational and Western medicine and control
Treat, be taken after mixing with liquid more than the moon, antisecosis, symptom improves, that is, starts chemotherapy, MFV schemes, and this Chinese medicine preparation is taken during chemotherapy and mitigates poison
Side reaction, 2 times a day, 1 bag, smoothly completes 6 chemotherapy treatments for 2 years every time, and every course for the treatment of 4-6 weeks, its total amount is 5 FU 5 fluorouracil
4-6g, mitomycin 16-24mg, vincristine 4-6mg.Continue medication 3 years after 2015, progress of half a year or 1 year is complete during this
Face is checked, and patient's rabat, abdomen B ultrasound, colonoscopy, carcinomebryonic antigen, erythrocyte sedimentation rate, hepatic and renal function, immunoglobulin belong to normal range (NR).
One 47 years old female patients, carcinoma of sigmoid was suffered from the beginning of 4 months 2010, ectomes and carries out through certain tumour hospital
Chemotherapy.After first quarter moon, because of physical weak obvious (blood picture:Hemoglobin 6.2g/L, leucocyte 1.3X 109/ L), nausea, vomiting, be
Chemotherapy is terminated, turns our hospital's treatment.Stomachache is seen when examining, diarrhoea (day skilful time or so), weak, the pale complexion in the whole body, dizzy, god is idle,
Oligotrichosis is withered and yellow, and tongue is white thin greasy, and arteries and veins moistens.Give Chinese medicine preparation of the present invention twice a day, every time 1 bag, after taking 2 weeks, stomachache
Mitigate, diarrhoea number is reduced, day 7-10 times.Defecated after one month normal, day 1-2 times, formed, basic disappearance of suffering from abdominal pain,
Dizzy, empty weary improvement, nausea are removed, and spirit is gradually bright.Hemogram checking:Hemoglobin 10g/L, leucocyte 3.8X109/L.Diet is gradually
Increase, complexion slightly takes a turn for the better.After half a year, sign disappears, and two is just normal, and antisecosis is very fast, blood picture and B ultrasound, cr check it is normal,
It is sick to cure rehabilitation.Self-induction recovers good, the working work in 2012.Adhere to continuing medication 2 years again afterwards, wherein again through 3 times
Check, no abnormality seen.So far, rehabilitation is as usual for follow-up, adheres to work of going to work.
Claims (6)
- A kind of 1. Chinese medicine for treating tumor in digestive tract:It is characterized in that by following parts by weight:Dried venom of toads 0.01-0.03 parts, scorpio 5-6 parts, tuber of pinellia 9-15 parts, excrementum pteropi (wine is ground) 3-5 parts, bighead atractylodes rhizome 8-10 parts, dried orange peel 2-3 parts, fructus amomi 2-3 parts, banksia rose 2-3 parts, Rhizoma cyperi 8-10 parts, Fructus meliae toosendan 5-7 parts, cattail pollen (stir-fry) 6-8 parts, fritillaria thunbergii 12-15 parts, radix glehniae 6-8 parts, Radix Angelicae Sinensis 10-12 parts, Radix rehmanniae recen 10-12 parts, radix glycyrrhizae 4-5 parts composition.
- A kind of 2. Chinese medicine for treating tumor in digestive tract according to claim 1:It is characterized in that by following parts by weight:Toad Crisp 0.02-0.03 parts, scorpio 5.5-6 parts, tuber of pinellia 12-15 parts, excrementum pteropi (wine is ground) 4-5 parts, bighead atractylodes rhizome 9-10 parts, dried orange peel 2.5-3 Part, fructus amomi 2.5-3 parts, banksia rose 2.5-3 parts, rhizoma cyperi 9-10 parts, Fructus meliae toosendan 6-7 parts, cattail pollen (stir-fry) 7-8 parts, fritillaria thunbergii 13-15 Part, radix glehniae 7-8 parts, Radix Angelicae Sinensis 11-12 parts, radix rehmanniae recen 11-12 parts, radix glycyrrhizae 4.5-5 parts composition.
- A kind of 3. Chinese medicine for treating tumor in digestive tract according to claim 1:It is characterized in that by following parts by weight:Toad Crisp 0.03 part, 6 parts of scorpio, 15 parts of the tuber of pinellia, 5 parts of excrementum pteropi (wine is ground), 10 parts of the bighead atractylodes rhizome, 3 parts of dried orange peel, 3 parts of fructus amomi, 3 parts of the banksia rose, perfume Attached 10 parts, 7 parts of Fructus meliae toosendan, 8 parts of cattail pollen (stir-frying), 15 parts of fritillaria thunbergii, 8 parts of radix glehniae, 12 parts of Radix Angelicae Sinensis, 12 parts of radix rehmanniae recen, radix glycyrrhizae 5 Part composition.
- A kind of 4. preparation method of traditional Chinese herbal decoction for treating tumor in digestive tract according to claim 1:It is characterized in that by Following steps are made:1):Weighed by above-mentioned formula:Excrementum pteropi (wine is ground), the bighead atractylodes rhizome, radix glehniae, radix glycyrrhizae, the water intense fire of 2 times of weight of addition is boiled to be changed Be cooked by slow fire 20 minutes, then add dried orange peel, the banksia rose, rhizoma cyperi, cattail pollen (stir-frying) mixing decoct and filter to obtain filtrate in 10 minutes;2):Scorpio, the tuber of pinellia, fructus amomi, Fructus meliae toosendan, fritillaria thunbergii, Radix Angelicae Sinensis, radix rehmanniae recen, the water for adding 2 times of weight are weighed, intense fire is boiled Change to be cooked by slow fire 30 minutes and filter, merge secondary concoction, stand 24 hours, take supernatant, add the dried venom of toads fine powder of corresponding weight Both may be used.
- A kind of 5. preparation method of Chinese herbal granules for treating tumor in digestive tract according to claim 1:It is characterized in that It is made up of following steps:1):Weighed by above-mentioned formula:Excrementum pteropi (wine is ground), the bighead atractylodes rhizome, radix glehniae, radix glycyrrhizae, the water intense fire of 2 times of weight of addition is boiled to be changed Be cooked by slow fire 20 minutes, then add dried orange peel, the banksia rose, rhizoma cyperi, cattail pollen (stir-frying) mixing decoct and filter to obtain filtrate in 10 minutes;2):Scorpio, the tuber of pinellia, fructus amomi, Fructus meliae toosendan, fritillaria thunbergii, Radix Angelicae Sinensis, radix rehmanniae recen, the water for adding 2 times of weight are weighed, intense fire is boiled Change to be cooked by slow fire 30 minutes and filter, merge secondary concoction, stand 24 hours, take supernatant, add the dried venom of toads fine powder of corresponding weight Relative density 1.35 or so (80 DEG C of heat are surveyed) thick medicinal extract is condensed into, is dried in vacuo, crushes, add appropriate pharmaceutical carrier and mix, 75% alcohol is pelletized, and is dried, is packed and produce.
- A kind of 6. Chinese medicine for treating tumor in digestive tract according to claim 1, it is characterised in that:Can be according to clinical requirement Required medicine pill, powder, paste, sublimed preparation is made.
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CN105535436A (en) * | 2016-01-04 | 2016-05-04 | 成都富豪斯生物科技有限公司 | Oral traditional Chinese medicine pills for treating oesophagitis and preparation method thereof |
CN108175816A (en) * | 2018-01-31 | 2018-06-19 | 黄河科技学院 | A kind of Chinese medicine for promoting apoptosis of tumor cells and preparation method thereof |
CN108261534A (en) * | 2018-01-31 | 2018-07-10 | 黄河科技学院 | A kind of Chinese medicine that tumour knurl is promoted to wither away and preparation method thereof |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108261534A (en) * | 2018-01-31 | 2018-07-10 | 黄河科技学院 | A kind of Chinese medicine that tumour knurl is promoted to wither away and preparation method thereof |
CN108619422A (en) * | 2018-05-23 | 2018-10-09 | 杜美丽 | A kind of antitumor Chinese and diplocardia biological heat energy therapy |
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Application publication date: 20171124 |