CN107375092A - It is a kind of with the plant residue composition of anti-inflammatory efficacy and its application - Google Patents
It is a kind of with the plant residue composition of anti-inflammatory efficacy and its application Download PDFInfo
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- CN107375092A CN107375092A CN201710704228.2A CN201710704228A CN107375092A CN 107375092 A CN107375092 A CN 107375092A CN 201710704228 A CN201710704228 A CN 201710704228A CN 107375092 A CN107375092 A CN 107375092A
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- extraction slag
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
It is made up of the invention discloses a kind of with the plant residue composition of anti-inflammatory efficacy and its application, described plant residue composition following mass percent component：Safflower extracts slag 0.6 3.4%, hawthorn extraction slag 0.5 4.1%, pseudo-ginseng extraction slag 0.3 2.7%.The plant residue composition is applied in shower cream, there is Bergamot Mint Extract, inhibiting bacteria and diminishing inflammation, antipruritic and other effects.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of plant residue composition with anti-inflammatory efficacy and its should
With.
Background technology
In daily life, people are after motion, work, and because of heating perspiration, pore is expanded, now easily by bacterium sense
Dye, occur pruitus the problems such as.Meanwhile the bacterium on skin also enters in vivo easily by hand from channels such as mouth, noses, causes
Disease.Thus, people often by the way of shower, eliminate itch, sterilization.Shower cream is daily daily chemical product, and it is needed
The amount of asking is increasing, and the shower cream species of in the market is various, but due to surface-active of most of shower cream all containing synthesis
The biochemical compositions such as the preservative of agent and other tool carcinogenicities, alkalescence is stronger, larger to skin irritation, easily causes to do after washing
Puckery, tight, itch, certain negative effect and threat are produced to the health of people.Therefore, it is badly in need of developing a moderate performance,
With good washability, make skin tender, can anti-inflammatory anti-itch, the shower cream of sterilization.
The content of the invention
, will it is an object of the invention to provide a kind of plant residue composition with anti-inflammatory efficacy for prior art
The plant residue composition is applied in shower cream, has regulation fat secretion, antibacterial, antipruritic and other effects.
To achieve the above object, the present invention provides following technical scheme：
A kind of plant residue composition with anti-inflammatory efficacy extracts slag by safflower, hawthorn extracts slag and pseudo-ginseng extracts slag group
Into.
Further, the mass percent of described safflower extraction slag, hawthorn extraction slag and pseudo-ginseng extraction slag is as follows：Safflower
Extract slag 0.6-3.4%, hawthorn extraction slag 0.5-4.1%, pseudo-ginseng extraction slag 0.3-2.7%.
Preferably, the mass percent of described safflower extraction slag, hawthorn extraction slag and pseudo-ginseng extraction slag is as follows：Safflower carries
Take slag 0.8-3.0%, hawthorn extraction slag 0.7-3.5%, pseudo-ginseng extraction slag 0.5-2.5%.
Optimal, the mass percent that described safflower extraction slag, hawthorn extraction slag and pseudo-ginseng extracts slag is as follows：Safflower carries
Take slag 1.0-2.7%, hawthorn extraction slag 1.2-3.0%, pseudo-ginseng extraction slag 0.8-2.2%.
A kind of preparation method of the plant residue composition with anti-inflammatory efficacy is as follows：Safflower, hawthorn and pseudo-ginseng is collected to plant
Plant residue raw material of the raw material after extraction and application, it is separately dried and is crushed to 10-15 mesh, finally mixed according to aforementioned proportion
Conjunction.
Further, the described plant residue raw material entered after extraction and application refers to carry by alcohol extracting, water extraction, oil immersion
Left residue after one or more techniques extraction in method, supercritical carbon dioxide extraction method.
The present invention also provides a kind of plant residue composition with anti-inflammatory efficacy and is preparing the application of cosmetics, and described
Cosmetics are shower cream.
Further, described shower cream includes the component of following mass percent：Above-mentioned plant residue composition
3.0-7.9%, laureth sodium sulfovinate 8.5-12%, cocoamido betaine 6.3-13%, glycerine 2.1-4.5%, coconut palm
Oil base glucoside 3.2-6.9%, sodium chloride 0.2-0.5%, the stearic acid ester 2.5-5.7% of ethylene glycol two, EDETATE SODIUM 0.03-
0.1%th, citric acid 0.01-0.05%, methylchloroisothiazandnone 0.001-0.005%, methylisothiazolinone 0.001-
0.003%th, essence 0.01-0.05%, deionized water surplus.
Several components in the plant residue used in the present invention are introduced below：
Safflower dries flower, alias safflower, FLOS CARTHAMI from Henan of China, thorn safflower etc. for feverfew safflower.Safflower is in China's main product
In Xinjiang, Hunan, Zhejiang, Yunnan and other places, there is cultivation all parts of the country.Its property pungent-warm, the silicon heart, Liver Channel, it is that invigorate blood circulation, dissolving stasis are stopped
The good medicine of pain.The chemical composition of safflower mainly includes flavonoids, alkaloids, carbene class, spermidine class, lignanoids, sesquialter
Terpene, organic acid, sterols, alkyl diol class, polysaccharide and other compositions etc..It is rear remaining that safflower slag is that safflower is extracted
Residue, free radical generation can be reduced, existing result of study shows, safflower and its active component can regulate and control a variety of anti-with inflammation
Should the growth factor of correlation and the gene expression of cell adhesion molecule.Carthamin yellow inflammatory reaction capable of inhibiting cell, reduce
Expression of inflammatory cytokines, prevent unstable plaque rupture.Hydroxyl radical carthamin yellow carthamus A can suppress the work of inflammatory cell leucocyte
Change, lipopolysaccharide-induced damage is played a protective role.
Hawthorn is rose family may, is the special product fruit tree in China, and Chinese medicine uses being dried to for large-fruited Chinese hawthorn and hawthorn
Ripe fruit, tool food digesting stomach fortifying, scattered stasis, change the effect of turbid lipid-loweringing, adjusted in cardio-cerebrovascular, digestive system and blood fat
Section, glycometabolism etc. are respectively provided with stronger pharmacological action.Hawthorn has resistant function to a variety of bacillus and coccus, such as Fu Shi bars
Bacterium, Song Shi bacillus, Si Mishi bacillus, proteus, Nai Shi bacillus, bacillus anthracis, corynebacterium diphtheriae, typhoid bacillus and hemolytic chain
Coccus etc..Chinese hawthorn seed has preferable to colibacillus, staphylococcus aureus, pseudomonas aeruginosa, Candida albicans
Bactericidal effect, and stability is preferable.
Pseudo-ginseng is Araliaceae, and dry root is used as medicine.Alias mountain knee, invaluable, Typhonium flagelliforme (Lodd.) Blume, field paint, pseudo-ginseng, ginseng three
7th, blood ginseng, Panax pseudoginseng, Yunnan pseudo-ginseng.Pseudo-ginseng have stop blooding, invigorate blood circulation, enriching blood, antithrombotic, protect cardiac muscle, resisting coronary heart disease, protection
Brain tissue, expand blood vessel and decompression, improve memory, analgesia, calmness, liver protection, hypoglycemic, anti-aging, nourishing, strong, immune adjust
The multiple pharmacological effects such as section.The inflammatory cell that arasaponin (PNS) can substantially suppress carrageenan induction increases and oozed out with albumen
Outside, also with significant antiinflammatory action.Its mechanism of action is：PNS can prevent the rise of free calcium level in inflammatory cell, suppress to fill
The activity of phospholipase A2 (PLA2), reduces the release of dinoprostone in flow liquid.
Compared with prior art, it is the device have the advantages that as follows：Radix Angelicae Sinensis extraction slag, safflower in product of the present invention
Slag, pseudo-ginseng extraction slag compounding use in specific proportions are extracted, wherein, inflammatory reaction, the reduction of safflower extraction slag suppression cell are scorching
Disease cytokine-expressing, prevent unstable plaque rupture；The slag of hawthorn extraction simultaneously can reduce sebum secretion, and pass through antibacterial work
For suppressing the breeding of inflammation bacterial fungus；Slag is extracted finally by pseudo-ginseng to prevent the rise of free calcium level in inflammatory cell,
Three kinds of composition synergies, effectively play anti-inflammatory efficacy comprehensively.The present invention is mainly peculiar using also there being its raw material in residue
Active component, act synergistically to reach anti-inflammatory the effect of.These residues are effectively utilized, turns waste into wealth, reduces production cost,
The utilization rate of plant material is improved, while contributes to environmental protection.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated：
The shower cream embodiment 1~5 of the present invention is formulated, and is shown in Table 1.
Table 1
The preparation method of plant residue composition is as follows：
The plant residue raw material of safflower, hawthorn and pseudo-ginseng plant material after extraction and application is collected, is separately dried simultaneously powder
It is broken to arrive 10-15 mesh, finally mixed according to aforementioned proportion.
Comparative example 1：
Safflower extraction slag is not added in difference with embodiment 3 only, and remaining each material addition, conditions and technology of preparation is not
Change.
Comparative example 2：
Hawthorn extraction slag is not added in difference with embodiment 3 only, and remaining each material addition, conditions and technology of preparation is not
Change.
Comparative example 3：
Pseudo-ginseng extraction slag is not added in difference with embodiment 3 only, and remaining each material addition, conditions and technology of preparation is not
Change.
Comparative example 4：
Compared with Example 3, safflower extraction slag, hawthorn extraction slag, pseudo-ginseng extraction slag do not add, remaining each material addition
Amount, conditions and technology of preparation do not change still.
Press down oily efficacy validation：
Shower cream sample, which is made, by Example formulations invites the volunteer of 60 20-40 year to try out, and takes appropriate shower daily
Dew is cleaned, and is evaluated after continuously trying out 4 weeks.Subject enrollment standard is people of the Oily without skin disease allergies,
Difference between each group does not have statistical significance.Using the skin of German Courage Khazaka companies (German CK companies)
Fat content Sebumeter test probes are detected, and patient volunteer was in the 0th day, the 14th day, the skin oil and fat of the 28th day
Content, as a result as shown in table 2.
Table 2
As shown in Table 2, basic formula of bath cream only contains cleaning function, can only somewhat reduce skin oil after cleaning
The content of fat, the fat content of skin can not be controlled for a long time.Each composition by adding this composition can play certain
Press down oily effect, but if not to scale (NTS) or incomplete addition all the components, press down oily DeGrain, it is necessary to using the long period
Ideal effect is can be only achieved, only when completely the addition present composition can be only achieved preferable fungistatic effect in proportion.
Bacteriostasis efficacy is verified：
With the bath foam made described in embodiment 3, common mixed cell (golden yellow grape in the work of single inoculation cosmetics
Coccus SA, Escherichia coli EC, pseudomonas aeruginosa PA), mixed fungus (black-koji mould AN, the false screw mandrel bacterium CA of white), according to change
Cosmetic, toilet articles and fragrance association (CTFA) Microbial Challenge test method, sample monitoring cycle are 28 days, are during which distinguished
Sample detection was carried out at the 2nd, 7,14 and 28 day, calculates the clump count (cfu) per mL.As a result it is as shown in table 3.
Table 3
| Strain | 0 day | 7 days | 14 days | 21 days | 28 days |
| Mixed cell | 3x107 | 0 | 0 | 0 | 0 |
| Mixed fungus | 5x105 | 0 | 0 | 0 | 0 |
The result of table 3 shows, with the shower cream obtained described in embodiment 3, can effectively suppress the growth of bacterium and fungi, have
Good antibacterial and anti-inflammation functions.
Above example is merely to illustrate embodiment of the present invention, does not have any formal limit to the present invention
System；It is any to be engaged in professional and technical personnel, all have the ability using the technology contents having revealed that, some are made to it and changes or repaiies
Decorations, turn into the equivalent embodiment of equivalent variations.According to the technology of the present invention essence, simply modification, equivalent variations are carried out to the present invention
With modification, belong in the range of technical solution of the present invention.
Claims (9)
1. a kind of plant residue composition with anti-inflammatory efficacy, it is characterised in that described plant residue composition is by safflower
Extract slag, hawthorn extraction slag and pseudo-ginseng extraction slag composition.
2. a kind of plant residue composition with anti-inflammatory efficacy according to claim 1, it is characterised in that described is red
The mass percent of flower extraction slag, hawthorn extraction slag and pseudo-ginseng extraction slag is as follows：
Safflower extraction slag 0.6-3.4%
Hawthorn extraction slag 0.5-4.1%
Pseudo-ginseng extraction slag 0.3-2.7%.
3. a kind of plant residue composition with anti-inflammatory efficacy according to claim 2, it is characterised in that described is red
The mass percent of flower extraction slag, hawthorn extraction slag and pseudo-ginseng extraction slag is as follows：
Safflower extraction slag 0.8-3.0%
Hawthorn extraction slag 0.7-3.5%
Pseudo-ginseng extraction slag 0.5-2.5%.
4. a kind of plant residue composition with anti-inflammatory efficacy according to claim 3, it is characterised in that described is red
The mass percent of flower extraction slag, hawthorn extraction slag and pseudo-ginseng extraction slag is as follows：
Safflower extraction slag 1.0-2.7%
Hawthorn extraction slag 1.2-3.0%
Pseudo-ginseng extraction slag 0.8-2.2%.
A kind of 5. plant residue composition with anti-inflammatory efficacy according to claim any one of 1-4, it is characterised in that
The preparation method of described plant residue composition is as follows：Safflower, hawthorn and pseudo-ginseng plant material are collected after extraction and application
Plant residue raw material, be separately dried and be crushed to 10-15 mesh, finally mixed according to aforementioned proportion.
6. a kind of plant residue composition with anti-inflammatory efficacy according to claim 5, it is characterised in that described enters
The plant residue raw material crossed after extraction and application refers to by alcohol extracting, water extraction, oil immersion formulation, supercritical carbon dioxide extraction method
Left residue after one or more technique extractions.
7. a kind of plant residue composition with anti-inflammatory efficacy according to claim any one of 1-6 is preparing cosmetics
Application.
8. application according to claim 7, it is characterised in that described cosmetics are shower cream.
9. a kind of shower cream with anti-inflammatory efficacy, it is characterised in that described shower cream includes following mass percent
Component：Plant residue composition 3.0-7.9%, laureth sodium sulfovinate 8.5-12%, cocounut oil as claimed in claim 1
Amide betaine 6.3-13%, glycerine 2.1-4.5%, cocoyl glucoside 3.2-6.9%, sodium chloride 0.2-0.5%, ethylene glycol
Two stearic acid ester 2.5-5.7%, EDETATE SODIUM 0.03-0.1%, citric acid 0.01-0.05%, methylchloroisothiazandnone
0.001-0.005%, methylisothiazolinone 0.001-0.003%, essence 0.01-0.05%, deionized water surplus.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710704228.2A CN107375092A (en) | 2017-08-16 | 2017-08-16 | It is a kind of with the plant residue composition of anti-inflammatory efficacy and its application |
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| CN201710704228.2A CN107375092A (en) | 2017-08-16 | 2017-08-16 | It is a kind of with the plant residue composition of anti-inflammatory efficacy and its application |
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| CN107375092A true CN107375092A (en) | 2017-11-24 |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101869541A (en) * | 2010-07-20 | 2010-10-27 | 湖南工程学院 | Skin care product comprising plant extract and preparation method thereof |
| CN103027872A (en) * | 2011-10-10 | 2013-04-10 | 裴兆勇 | Body wash with efficacy of preventing and treating dermatitis and multiple epifolliculitis |
| CN103655281A (en) * | 2013-11-20 | 2014-03-26 | 青岛晨讯通商贸有限公司 | Bacteriostasis shower gel |
| CN106344440A (en) * | 2016-10-31 | 2017-01-25 | 烟台市昊星晟信息技术有限公司 | Method for preparing Chinese herbal medicine anti-hair-loss shampoo |
-
2017
- 2017-08-16 CN CN201710704228.2A patent/CN107375092A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101869541A (en) * | 2010-07-20 | 2010-10-27 | 湖南工程学院 | Skin care product comprising plant extract and preparation method thereof |
| CN103027872A (en) * | 2011-10-10 | 2013-04-10 | 裴兆勇 | Body wash with efficacy of preventing and treating dermatitis and multiple epifolliculitis |
| CN103655281A (en) * | 2013-11-20 | 2014-03-26 | 青岛晨讯通商贸有限公司 | Bacteriostasis shower gel |
| CN106344440A (en) * | 2016-10-31 | 2017-01-25 | 烟台市昊星晟信息技术有限公司 | Method for preparing Chinese herbal medicine anti-hair-loss shampoo |
Non-Patent Citations (3)
| Title |
|---|
| 冯彬彬 等主编: "《中药药理与应用》", 30 November 2015, 中国中医药出版社 * |
| 国家食品药品监督管理总局执业药师资格认证中心 组织编写: "《中药学专业知识（二）》", 31 January 2016, 中国医药科技出版社 * |
| 段二虎 编著: "《药补不如食补 你不可不知的食疗秘密》", 31 May 2012, 天津科学技术出版社 * |
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Application publication date: 20171124 |