CN107349119B - Stable amino acid soap and preparation method thereof - Google Patents
Stable amino acid soap and preparation method thereof Download PDFInfo
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- CN107349119B CN107349119B CN201710613746.3A CN201710613746A CN107349119B CN 107349119 B CN107349119 B CN 107349119B CN 201710613746 A CN201710613746 A CN 201710613746A CN 107349119 B CN107349119 B CN 107349119B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
Abstract
The invention provides an amino acid soap which comprises the following raw materials in parts by weight: 0.002-0.2 part of a benzene azole sulfonate derivative; 0.002-0.2 parts of tris (tetramethylhydroxypiperidinol) citrate; 30-60 parts of N-acylamino acid; 15-30 parts of arginine; 3-10 parts of triethanolamine; 2-20 parts of strong base; 10-30 parts of a humectant; 0.2-10 parts of a skin feel modifier; the N-acyl amino acid is selected from one or more of lauroyl glutamic acid, cocoyl glutamic acid, myristoyl glutamic acid, stearoyl glutamic acid, palmitoyl glutamic acid and cocamido propionic acid. The amino acid soap provided by the invention has a synergistic effect by adding the specific benzene azole sulfonate derivative and the tri (tetramethyl hydroxypiperidinol) citrate into the amino acid soap, so that the amino acid soap can more effectively resist discoloration caused by factors such as ultraviolet irradiation, oxidation and the like.
Description
Technical Field
The invention relates to the technical field of daily necessities, in particular to a stable amino acid soap and a preparation method thereof.
Background
The soap is a common washing article in daily life, and has the advantages of convenient carrying, durability, environmental protection and the like. The soap made on the basis of the soap base is extremely strong in alkalinity, the pH value is generally more than 9, according to the traditional habits of Chinese people, the soap brings astringent feeling during washing, but the strong-alkalinity soap usually causes people to feel strong tightness after being wiped dry, and the soap can form precipitates with calcium, magnesium, salt and the like in hard water, so that the washing capacity of the soap is lost.
The amino acid soap is a novel face-washing soap which is started in recent years, has the greatest characteristic that an amino acid surfactant is used for replacing fatty acid salt to prepare a soap base, has various advantages of high safety to environment and organisms, good skin affinity and the like, has a pH value close to that of human skin, and is soft and not tight after being washed and dried. However, due to overheating and illumination in the preparation and storage processes of the amino acid soap, the triethanolamine salt turns yellow due to ultraviolet irradiation and oxidation, the prior art mainly prevents the amino acid soap from changing color by adding sodium sulfite or sodium metabisulfite as an antioxidant, but the effect is not ideal, the amino acid soap still gradually changes color along with the prolonging of the standing time, and the sodium nitrite and the sodium metabisulfite have large irritation to the skin, so that the mildness of the amino acid soap is greatly damaged, and the triethanolamine salt can generate adverse effects on the health of a human body after long-term use.
Disclosure of Invention
In view of the above, the technical problem to be solved by the present invention is to provide an amino acid soap, which can more effectively resist the discoloration caused by ultraviolet rays and oxidation, and has moderate hardness while exhibiting weak acidity.
The invention provides an amino acid soap which is characterized by comprising the following raw materials in parts by weight:
the N-acyl amino acid is selected from one or more of lauroyl glutamic acid, cocoyl glutamic acid, myristoyl glutamic acid, stearoyl glutamic acid, palmitoyl glutamic acid and cocamido propionic acid.
Preferably, the strong base is selected from one or more of sodium hydroxide and potassium hydroxide.
Preferably, the humectant is one or more selected from glycerol, sorbitol, propylene glycol and polyethylene glycol.
Preferably, the skin feeling modifier is one or more selected from the group consisting of polyglycerol-10, betaine, urea, allantoin, seaweed extract, hyaluronic acid, sodium hyaluronate, trehalose, maltitol, erythritol, mannitol and sucrose.
Preferably, the amino acid soap comprises the following raw materials in parts by weight:
preferably, the method further comprises the following steps:
0.02-5 parts by weight of B vitamins;
0.01-0.3 parts by weight of creatine;
the B vitamins are selected from one or more of folic acid, nicotinamide, vitamin B6 and vitamin B12.
Preferably, the method further comprises the following steps:
0-5 parts by weight of an aromatic agent;
the flavoring agent is one or more selected from essence and essential oil.
Preferably, a solvent is also included; the solvent is one or more selected from deionized water, calendula water, lavender water, rose water, white-flower spring yellow chrysanthemum water, chamomile flower water, cherry flower water and witch hazel flower water.
The invention provides a preparation method of amino acid soap, which comprises the following steps:
A) mixing N-acylamino acid and a humectant, heating and stirring to obtain a first mixed solution;
mixing and heating triethanolamine, arginine and strong base to obtain a second mixed solution;
B) mixing the first mixed solution and the second mixed solution, mixing the mixed solution with a skin feel regulator, cooling the mixed solution after mixing, and mixing the cooled mixed solution with a benzene azole sulfonate derivative and tris (tetramethyl hydroxypiperidinol) citrate to obtain a third mixed solution;
C) and filling the third mixed solution into a mold to obtain the amino acid soap.
Preferably, the heating temperature of the heating and stirring in the step A) is 80-95 ℃; the heating temperature of the mixing and heating is 80-95 ℃.
Compared with the prior art, the invention provides an amino acid soap which comprises the following raw materials in parts by weight: 0.002-0.2 part of a benzene azole sulfonate derivative; 0.002-0.2 parts of tris (tetramethylhydroxypiperidinol) citrate; 30-60 parts of N-acylamino acid; 15-30 parts of arginine; 3-10 parts of triethanolamine; 2-20 parts of strong base; 10-30 parts of a humectant; 0.2-10 parts of a skin feel modifier; the N-acyl amino acid is selected from one or more of lauroyl glutamic acid, cocoyl glutamic acid, myristoyl glutamic acid, stearoyl glutamic acid, palmitoyl glutamic acid and cocamido propionic acid. The amino acid soap provided by the invention can play a synergistic effect by selecting the specific benzene azole sulfonate derivative and the tri (tetramethyl hydroxypiperidinol) citrate and adding the derivatives into the amino acid soap according to a specific ratio, so that the amino acid soap can more effectively resist discoloration caused by factors such as ultraviolet irradiation and oxidation, and simultaneously keep the fragrance and transparency of the amino acid soap. Meanwhile, the N-acylamino acid, the triethanolamine, the arginine and the strong base are selected as specific components and combined with specific content, so that the finally prepared amino acid soap is moderate in hardness within a weakly acidic pH value range, and the finally prepared amino acid soap is good in skin feeling effects such as appearance, cleaning capacity, whitening and moisturizing by matching with the humectant and the skin feeling regulator in a specific proportion.
Detailed Description
The invention provides an amino acid soap which comprises the following raw materials in parts by weight:
the N-acyl amino acid is selected from one or more of lauroyl glutamic acid, cocoyl glutamic acid, myristoyl glutamic acid, stearoyl glutamic acid, palmitoyl glutamic acid and cocamido propionic acid.
The raw material of the amino acid soap provided by the invention comprises 0.002-0.2 part by weight of a benzene azole sulfonate derivative; preferably 0.01 to 0.2 part by weight of a benzoxazole sulfonate derivative; more preferably 0.02 to 0.2 parts by weight of a benzene azole sulfonate derivative; most preferably, the benzene azole sulfonate derivative comprises 0.02-0.1 weight part of benzene azole sulfonate derivative.
The specific composition of the above-mentioned benzene azole sulfonate derivative is not limited in the present invention, and those skilled in the art are familiar with the present invention, and commercially available compounds are preferred.
The raw material of the amino acid soap provided by the invention comprises 0.002-0.2 part by weight of tri (tetramethyl hydroxypiperidinol) citrate; preferably, the composition comprises 0.01 to 0.2 weight part of tris (tetramethylhydroxypiperidinol) citrate; more preferably, the composition comprises 0.02 to 0.2 parts by weight of tris (tetramethylhydroxypiperidinol) citrate; most preferably, the composition comprises 0.02 to 0.1 part by weight of tris (tetramethylhydroxypiperidinol) citrate.
The specific composition of the tris (tetramethylhydroxypiperidinol) citrate is not limited in the present invention, and is well known to those skilled in the art, and is preferably commercially available.
The amino acid soap provided by the invention can play a synergistic effect by selecting the specific benzene azole sulfonate derivative and the tri (tetramethyl hydroxypiperidinol) citrate and adding the derivatives into the amino acid soap according to a specific ratio, so that the amino acid soap can more effectively resist discoloration caused by factors such as ultraviolet irradiation and oxidation, and simultaneously keep the fragrance and transparency of the amino acid soap.
The raw material of the amino acid soap provided by the invention comprises 30-60 parts by weight of N-acyl amino acid. Preferably 35 to 59 parts by weight of an N-acylamino acid; more preferably 40 to 57 parts by weight of an N-acylamino acid; most preferably 40 to 55 parts by weight of an N-acylamino acid.
The N-acyl amino acid is selected from one or more of lauroyl glutamic acid, cocoyl glutamic acid, myristoyl glutamic acid, stearoyl glutamic acid, palmitoyl glutamic acid and cocamido propionic acid; preferably one or more of stearoyl glutamic acid, palmitoyl glutamic acid and cocamido propionic acid.
In the present invention, the source of the N-acylamino acid is not limited and may be commercially available.
The raw material of the amino acid soap provided by the invention comprises 15-30 parts by weight of arginine; preferably 18-28 parts of arginine; more preferably 20-27 parts of arginine.
The arginine is not limited in the source thereof and may be commercially available.
The amino acid soap provided by the invention comprises 3-10 parts by weight of triethanolamine. Preferably 4 to 9 parts by weight of triethanolamine; more preferably 5 to 9 parts by weight of triethanolamine; most preferably 5 to 8 parts by weight of triethanolamine. In the present invention, the source of the triethanolamine is not limited and may be commercially available.
The raw material of the amino acid soap provided by the invention comprises 2-20 parts by weight of strong base; preferably, the alkali comprises 3-18 parts by weight of alkali; more preferably, the alkali comprises 5-18 parts by weight of alkali; most preferably, the alkali is contained in an amount of 7 to 15 parts by weight. The strong base is preferably selected from one or more of sodium hydroxide and potassium hydroxide. In the present invention, the sources of the sodium hydroxide and the potassium hydroxide are not limited and may be those commercially available.
The amino acid soap provided by the invention creatively selects N-acyl amino acid, triethanolamine, arginine and strong base as specific components to combine specific content, so that the finally prepared amino acid soap has moderate hardness in a weak acidic pH value range and good comprehensive performance.
The amino acid soap provided by the invention comprises 10-30 parts by weight of humectant; preferably 12 to 28 parts by weight of a humectant; more preferably 12 to 25 parts by weight of a humectant; most preferably 12 to 20 parts by weight of a humectant.
The humectant is preferably one or more selected from glycerol, sorbitol, propylene glycol and polyethylene glycol.
The sources of the glycerin, sorbitol, propylene glycol and polyethylene glycol are not limited in the present invention, and they may be commercially available.
The raw material of the amino acid soap provided by the invention comprises 0.2-10 parts by weight of a skin feel modifier; preferably 1-9 parts by weight of a skin feel modifier; more preferably 1 to 7 parts by weight of a skin feel modifier; most preferably 1 to 5 parts by weight of a skin feel modifier.
The skin feeling regulator is preferably one or more selected from polyglycerol-10, betaine, urea, allantoin, seaweed extract, hyaluronic acid, sodium hyaluronate, trehalose, maltitol, erythritol, mannitol and sucrose.
In the present invention, the source of the skin feel modifier is not limited and may be commercially available.
According to the amino acid soap provided by the invention, N-acylamino acid, triethanolamine, arginine and strong base are selected as specific components, and specific contents are combined, so that the finally prepared amino acid soap is moderate in hardness within a weak acidic pH value range, and meanwhile, the finally prepared amino acid soap is moderate in weak acidic pH value and hardness by matching with a humectant and a skin feeling regulator in a specific proportion, and is good in whitening, skin elasticity increasing and moisturizing effects.
In some embodiments of the present invention, the amino acid soap preferably comprises the following raw materials in parts by weight:
in another embodiment of the present invention, the amino acid soap preferably comprises the following raw materials in parts by weight:
in the invention, the raw material of the amino acid soap preferably also comprises 0.02-5 parts by weight of B vitamins; more preferably, the vitamin B complex also comprises 0.2-5 parts by weight of B vitamins.
The B vitamins are preferably selected from one or more of folic acid, nicotinamide, vitamin B6 and vitamin B12.
The inventor creatively discovers that the amino acid soap prepared by adding B vitamins in a specific ratio into the components of the N-acyl amino acid, the triethanolamine, the arginine, the strong base, the humectant and the skin feel regulator has good whitening, skin elasticity increasing and moisturizing effects.
In the invention, the raw material of the amino acid soap preferably further comprises 0.01-0.3 weight part of creatine; preferably, 0.05 to 0.3 weight part of creatine is also included.
The inventor creatively discovers that the amino acid soap prepared by adding the B vitamins and the creatine in a specific ratio into the components of the N-acyl amino acid, the triethanolamine, the arginine, the strong base, the humectant and the skin feel regulator has a good effect, and the B vitamins and the creatine can play a synergistic effect to whiten the amino acid soap, increase the skin elasticity and have a better moisturizing effect.
In the invention, the raw material of the amino acid soap preferably further comprises 0-5 parts by weight of an aromatic agent; more preferably 0.1 to 3 parts by weight of an aromatic agent; most preferably, the perfume composition comprises 0.2-2 parts by weight of the perfume.
In the invention, the flavoring agent is preferably selected from one or more of essence and essential oil.
In the present invention, the raw material of the amino acid soap preferably further includes a solvent in a balance, the total amount being 100%.
The solvent is preferably one or more selected from deionized water, calendula water, lavender water, rose water, white-flower chamomile water, cherry flower water and witch hazel flower water.
The inventor creatively discovers that the pH value of the finally prepared amino acid soap is weakly acidic, the hardness is moderate, and the amino acid soap has good whitening, skin elasticity increasing and moisturizing effects by adding the fragrance-applying agent, the appearance modifying agent and the solvent in a specific ratio into the components of the N-acyl amino acid, the triethanolamine, the arginine, the strong base, the moisturizing agent and the skin feeling modifier.
The invention provides a preparation method of amino acid soap, which comprises the following steps:
A) mixing N-acylamino acid and a humectant, heating and stirring to obtain a first mixed solution;
mixing and heating triethanolamine, arginine and strong base to obtain a second mixed solution;
B) mixing the first mixed solution and the second mixed solution, mixing the mixed solution with a skin feel regulator, cooling the mixed solution after mixing, and mixing the cooled mixed solution with a benzene azole sulfonate derivative and tris (tetramethyl hydroxypiperidinol) citrate to obtain a third mixed solution;
C) and defoaming the third mixed solution, filling the third mixed solution into a mold, and thus obtaining the amino acid soap.
The method comprises the steps of mixing N-acylamino acid and a humectant, heating and stirring to obtain a first mixed solution.
The specific components and proportions of the N-acyl amino acid and the humectant are clearly described above, and are not described in detail herein.
The specific manner of stirring according to the present invention is not limited, as is well known to those skilled in the art; the heating temperature of the heating and stirring is preferably 80-95 ℃; more preferably 80 to 90 ℃.
If a solvent is also included, the N-acylamino acid, the humectant and the solvent are mixed in this step.
Mixing and heating triethanolamine, arginine and strong base to obtain a second mixed solution.
The specific components and proportions of the triethanolamine, the arginine and the strong base are clearly described in the invention, and are not described in detail herein.
According to the present invention, the specific mode of mixing is not limited, and it is preferable to stir after mixing. The heating temperature of the mixing and heating is preferably 80-95 ℃; more preferably 80 to 90 ℃.
If a solvent is also included, triethanolamine, arginine, a strong base, and a solvent are mixed in this step.
Mixing the first mixed solution and the second mixed solution, and mixing with the skin feeling regulator after mixing.
The specific components and proportions of the skin feel modifier are clearly described above, and are not repeated herein.
Cooling after mixing, and mixing with a benzene thiazole sulfonate derivative and tris (tetramethyl hydroxypiperidinol) citrate to obtain a third mixed solution;
the present invention is not limited to the specific manner of mixing, and those skilled in the art will be familiar with the present invention.
The temperature of the mixed cooling is preferably reduced to 50-60 ℃; more preferably, the temperature is reduced to 55 to 60 ℃.
And defoaming the third mixed solution after obtaining the third mixed solution, and filling the third mixed solution into a mold to obtain the amino acid soap.
The invention can also be mixed with one or more of B vitamins, creatine and flavoring agents after being cooled, and the mixture is placed in a die for filling after standing and defoaming to obtain the amino acid soap.
The present invention is not limited to the specific manner of filling into the mold, and the filling method is well known to those skilled in the art.
The invention provides an amino acid soap which comprises the following raw materials in parts by weight: 0.002-0.2 part of a benzene azole sulfonate derivative; 0.002-0.2 parts of tris (tetramethylhydroxypiperidinol) citrate; 30-60 parts of N-acylamino acid; 15-30 parts of arginine; 3-10 parts of triethanolamine; 2-20 parts of strong base; 10-30 parts of a humectant; 0.2-10 parts of a skin feel modifier; the N-acyl amino acid is selected from one or more of lauroyl glutamic acid, cocoyl glutamic acid, myristoyl glutamic acid, stearoyl glutamic acid, palmitoyl glutamic acid and cocamido propionic acid. The amino acid soap provided by the invention can play a synergistic effect by selecting the specific benzene azole sulfonate derivative and the tri (tetramethyl hydroxypiperidinol) citrate and adding the derivatives into the amino acid soap according to a specific ratio, so that the amino acid soap can more effectively resist discoloration caused by factors such as ultraviolet irradiation and oxidation, and simultaneously keep the fragrance and transparency of the amino acid soap. Meanwhile, the N-acylamino acid, the triethanolamine, the arginine and the strong base are selected as specific components and combined with specific content, so that the finally prepared amino acid soap is moderate in hardness within a weakly acidic pH value range, and the finally prepared amino acid soap is capable of whitening, increasing skin elasticity and achieving good moisturizing effect by being matched with the moisturizing agent and the skin feeling conditioning agent in specific proportion.
The evaluation method of the amino acid soap in the embodiment of the invention mainly measures indexes such as peroxide value, color, aroma, transparency, hardness, pH value, skin whitening effect, anti-photoaging effect and the like of the amino acid soap.
And (3) measuring the peroxide value:
the amino acid soap samples of examples and comparative examples were placed in an indoor tray to simulate daily use, and the peroxide values of the amino acid samples of examples and comparative examples were measured at 0 month, 3 months, 6 months, 9 months, and 12 months, respectively. Peroxide number determination method: 2.0g of the sample was weighed and placed in a 250mL iodometric vial, and 30mL of a chloroform-glacial acetic acid mixture was added to dissolve the sample completely. Adding 1.00ml of saturated potassium iodide solution, tightly plugging a bottle cap, slightly shaking for 0.5min, then placing for 3min in the dark, taking out, adding 100ml of water, shaking up, immediately titrating with a sodium thiosulfate standard titration solution, adding 1ml of starch indicator when the mixture is light yellow, continuously titrating until the blue color disappears, taking the same amount of trichloromethane-glacial acetic acid solution, potassium iodide solution and water, and performing a reagent blank test according to the same method.
The peroxide value of the sample was calculated according to the following formula
X＝(V1－V2)×c×0.1269/m
Wherein X represents the peroxide number of the sample, g/100 g; v1-sample consumption sodium thiosulfate standard titration solution volume, ml; v2-reagent blank consumption sodium thiosulfate standard titration solution volume, ml; c, concentration of standard titration solution of sodium thiosulfate, mol/L; m-sample mass, g; 0.1269-and 1.00mL of sodium thiosulfate Standard titration solution [ c (Na)2S2O3) 1.000mol/L equivalent iodine mass, g.
Color determination:
the amino acid soap samples of examples and comparative examples were placed in an indoor tray to simulate daily use, and the color of the amino acid samples of examples and comparative examples was measured at 0 month, 3 months, 6 months, 9 months, and 12 months, respectively. The color measuring method comprises the following steps: color measurements of amino acid samples in examples and comparative examples were determined by sensory visual inspection, and the color of the amino acid samples in examples and comparative examples was rated by 30 consumers based on the control sample, and the average rating was calculated. The grades comprise 0-4 grades, and the smaller the grade is, the better the color retention effect is. The classification standard is as follows: the grading included a 0 rating (color between control 1 and control 2),
grade 1 (color between control 2 and control 3), grade 2 (color between control 3 and control 4),
grade 3 (color between control 4 and control 5) and grade 4 (color between control 5 and control 6). Controls 1, 2, 3, 4, 5, 6 were prepared as-is.
Measurement of fragrance:
the amino acid soap samples of examples and comparative examples were placed in an indoor tray to simulate daily use, and the fragrance of the amino acid samples of examples and comparative examples was measured at 0 month, 3 months, 6 months, 9 months, and 12 months, respectively. The aroma measurement method comprises the following steps: fragrance measurement of amino acid samples in examples and comparative examples the fragrance of the amino acid samples in examples and comparative examples was rated by olfactory identification with 30 consumers based on a control sample, and an average rating was calculated. The grades comprise 0-5 grades, and the smaller the grade is, the better the fragrance protection effect is. The classification standard is as follows: the grading included grade 0 (odor close to control 1), grade 1 (odor close to control 2), grade 2 (odor close to control 3), grade 3 (odor close to control 4), grade 4 (odor close to control 5), grade 5 (odor close to control 6). The control 1, 2, 3, 4, 5, 6 samples were prepared as follows:
and (3) transparency determination:
the amino acid soap samples of examples and comparative examples were placed in an indoor tray to simulate daily use, and the transparency of the amino acid samples of examples and comparative examples was measured at 0 month, 3 months, 6 months, 9 months, and 12 months, respectively. The transparency determination method comprises the following steps: an amino acid soap sample was cut into a flat and smooth sheet having a thickness of 6.5 ± 0.15mm on both sides, and the sheet was inserted into a light-impervious stationary cylinder, and the numerical value of the light reflection factor (R0) when the sample was back-lined with black and the numerical value of the internal light reflection factor (R ∞) when the sample was back-lined with white were measured on a whiteness meter, and the transparency of the amino acid soap was calculated according to the formula T (%) (1-R0/R ∞) × 100%.
Hardness test method of amino acid soap: the amino acid soap was placed under the probe by a puncture test method, measured by a physical property tester, and the surface hardness/g, the internal hardness/g, and the viscosity/g · s were recorded.
The pH value detection method of the amino acid soap comprises the following steps: and adding water into the mixed solution before injection molding of the amino acid soap to prepare amino acid soap water, and detecting the pH value of the amino acid soap water by adopting a pH meter.
Skin whitening effect measurement:
and selecting the people with dark skin color, sunburn, chloasma and acne marks to participate in the test of the whitening effect of the amino acid soap. The amino acid soaps of examples and comparative examples were used in each group of 20 persons, and the average value of variations in ITA and the average value of variations in the number of spots before and after 4 weeks of continuous use of the amino acid soaps were measured and calculated using the ITA individual type angle.
And (3) measuring the anti-photoaging effect:
people with consistent skin quality and frequent outdoor work are selected to take the test of the anti-photoaging effect of the amino acid soap. The samples were divided into 20 persons each, using the amino acid soaps in examples and comparative examples, and after 4 weeks, the skin moisture and skin roughness were measured with a skin tester, and the average values were calculated.
Humidity test parameters
Roughness measurement parameters
In order to further illustrate the present invention, the amino acid soap and the preparation method thereof provided by the present invention will be described in detail below with reference to examples.
Examples 1 to 2, comparative examples 1 to 4
(1) The formula is as follows:
| polyglycerol-10 | 1％ | 1％ | 1％ | 1％ | 1％ | 1％ |
| Essence | 0.5％ | 0.5％ | 0.5％ | 0.5％ | 0.5％ | 0.5％ |
| Water (W) | Balance of | Balance of | Balance of | Balance of | Balance of | Balance of |
(2) Preparation method
1) Mixing lauroyl glutamic acid, glycerol and 50% water, stirring at constant speed, and heating to 80 deg.C.
2) Weighing triethanolamine (Dow), arginine, sodium hydroxide and water, heating to 80 deg.C
Then slowly adding the mixed solution obtained in the step 1), stirring uniformly, and adding polyglycerol-10.
3) Cooling to 55 deg.C, and rapidly adding essence, benzene azole sulfonate derivative and tris (tetramethyl)
Hydroxypiperidinol) citrate).
4) Filling in a mold, and quickly cooling and solidifying.
(3) Quality evaluation
The method is adopted to measure the performance of the product, wherein the measurement result is as follows:
table 1 shows the results of measuring the peroxide numbers of examples 1 to 2 of the present invention and comparative examples 1 to 4.
TABLE 1 results of measuring peroxide values of examples 1 to 2 and comparative examples 1 to 4
Table 2 shows the results of color measurement of examples 1 to 2 of the present invention and comparative examples 1 to 4.
TABLE 2 results of color measurement of examples 1 to 2 and comparative examples 1 to 4
Table 3 shows the results of the measurement of the fragrance in examples 1 to 2 of the present invention and in comparative examples 1 to 4.
TABLE 3 results of measurement of fragrance in examples 1 to 2 and comparative examples 1 to 4
Table 4 shows the transparency measurement results of examples 1 to 2 of the present invention and comparative examples 1 to 4.
TABLE 4 results of transparency measurement of examples 1 to 2 and comparative examples 1 to 4
Table 5 shows the hardness and pH values of examples 1 to 2 of the present invention and comparative examples 1 to 4.
TABLE 5 hardness and pH results for examples 1-2 and comparative examples 1-4
Table 6 shows the whitening effect and the anti-photoaging effect of examples 1 to 2 of the present invention and comparative examples 1 to 4.
TABLE 6 examples 1 to 2, comparative examples 1 to 4 whitening effect and anti-photoaging effect
Examples 3 to 6, comparative examples 5 to 8
(1) Formulation of
(2) Preparation method
1) Stearoyl glutamic acid, palmitoyl glutamic acid, cocamido propionic acid, glycerol and 50% water are mixed, stirred at a constant speed and heated to 90 ℃.
2) Mixing triethanolamine (Dow), arginine, sodium hydroxide and the rest water, heating to 90 ℃, slowly adding into the mixed solution obtained in the step 1), stirring uniformly, and adding polyglycerol-10.
3) Cooling to 60 deg.C, and rapidly adding folic acid, nicotinamide, creatine, essence, benzene azole sulfonate derivative and tris (tetramethylhydroxypiperidinol) citrate).
4) Filling in a mold, and quickly cooling and solidifying.
(3) Quality evaluation
The method is adopted to measure the performance of the product, wherein the measurement result is as follows:
table 7 shows the results of measuring the peroxide numbers of examples 3 to 6 according to the present invention and comparative examples 5 to 8.
TABLE 7 measurement results of peroxide values of examples 3 to 6 and comparative examples 5 to 8
Table 8 shows the results of color measurement of examples 3 to 6 according to the present invention and comparative examples 5 to 8.
TABLE 8 results of color measurement of examples 3 to 6 and comparative examples 5 to 8
Table 9 shows the results of the measurement of the fragrance in examples 3 to 6 of the present invention and in comparative examples 5 to 8.
TABLE 9 measurement results of fragrance of examples 3 to 6 and comparative examples 5 to 8
Table 10 shows the transparency measurement results of examples 3 to 6 according to the present invention and comparative examples 5 to 8.
TABLE 10 results of transparency measurement of examples 3 to 4 and comparative examples 5 to 8
Table 11 shows the hardness and pH values of examples 3 to 6 according to the present invention and comparative examples 5 to 8.
TABLE 11 results of hardness and pH values for examples 3 to 6 and comparative examples 5 to 8
The whitening effect and the anti-photoaging effect are shown in table 12:
table 12 shows the whitening effect and the anti-photoaging effect of examples 3 to 6 and comparative examples 5 to 8.
TABLE 12 whitening and anti-photoaging effects of examples 3 to 6 and comparative examples 5 to 8
Claims (7)
1. The amino acid soap is characterized by comprising a solvent and the following raw materials in parts by weight:
the strong base is selected from one or more of sodium hydroxide and potassium hydroxide;
the N-acyl amino acid is selected from one or more of lauroyl glutamic acid, myristoyl glutamic acid, stearoyl glutamic acid, palmitoyl glutamic acid and cocamido propionic acid;
the skin feeling regulator is one or more selected from polyglycerol-10, betaine, urea, allantoin, seaweed extract, hyaluronic acid, sodium hyaluronate, trehalose, maltitol, erythritol, mannitol and sucrose;
0.02-5 parts by weight of B vitamins;
0.01-0.3 parts by weight of creatine;
0 to 5 parts by weight of an aromatic agent
The B vitamins are selected from one or more of folic acid, nicotinamide, vitamin B6 and vitamin B12.
2. The amino acid soap of claim 1, wherein the humectant is selected from one or more of glycerin, sorbitol, propylene glycol, and polyethylene glycol.
3. The amino acid soap of claim 1, comprising the following raw materials in parts by weight:
4. the amino acid soap of claim 1, further comprising:
the flavoring agent is one or more selected from essence and essential oil.
5. The amino acid soap of claim 1, wherein the solvent is selected from one or more of deionized water, calendula water, lavender water, rose water, chamomile water, primrose water, and witch hazel water.
6. A method for preparing the amino acid soap according to claim 1, comprising the steps of:
A) mixing N-acylamino acid and a humectant, heating and stirring to obtain a first mixed solution;
mixing and heating triethanolamine, arginine and strong base to obtain a second mixed solution;
B) mixing the first mixed solution and the second mixed solution, mixing the mixed solution with a skin feel regulator, cooling the mixed solution after mixing, and mixing the cooled mixed solution with a benzene azole sulfonate derivative and tris (tetramethyl hydroxypiperidinol) citrate to obtain a third mixed solution;
C) and filling the third mixed solution into a mold to obtain the amino acid soap.
7. The preparation method according to claim 6, wherein the heating temperature of the heating and stirring in the step A) is 80-95 ℃; the heating temperature of the mixing and heating is 80-95 ℃.
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| CN108587802A (en) * | 2018-05-19 | 2018-09-28 | 山东朱氏药业集团有限公司 | A kind of transparent amino acid crystal soap and preparation method thereof |
| CN110090176A (en) * | 2019-05-07 | 2019-08-06 | 湖北中医药大学 | A kind of preparation method of the soap kind for shampoo |
| CN110257193A (en) * | 2019-06-05 | 2019-09-20 | 德化县祥山大果油茶有限公司 | A kind of natural tea oil handmade soap and preparation method thereof |
| US11485934B2 (en) * | 2019-08-02 | 2022-11-01 | The Procter & Gamble Company | Foaming compositions for producing a stable foam and methods for making same |
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