CN107260849A - A kind of traditional Chinese medicine oral liquid and its production method for treating anemopyretic cold - Google Patents
A kind of traditional Chinese medicine oral liquid and its production method for treating anemopyretic cold Download PDFInfo
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Abstract
The invention discloses a kind of traditional Chinese medicine oral liquid and its production method for treating anemopyretic cold.It is mainly prepared from traditional Chinese medicine ingredients such as baeckea frutescen, Swamp Mahogany Leaf, Honeysuckle flower, the capsule of weeping forsythia, sweet wormwood, schizonepeta, peppermint, radix bupleuri, Pogostemon cablin, folium artemisiae argyi, balloonflower root, dried orange peels through scientific matching, delivered with clearing heat and detoxicating, dispelling wind, cooling blood and dissolving stasis, blood circulation and channel invigorating, clearing heat and promoting diuresis, the effect of removing toxicity for detumescence, so as to reach the purpose for the treatment of anemopyretic cold.
Description
Technical field
The present invention relates to a kind of extract oral liquid product, particularly a kind of traditional Chinese medicine oral liquid for treating anemopyretic cold and its life
Production method.
Background technology
Anemopyretic cold is that heresy criminal table, the lung qi of wind-heat become estranged caused.Symptoms are heating weight, micro- foul wind, distending pain in the head, had
Sweat, red swelling and pain of throat, cough, glutinous or yellow phlegm, the yellow tears of nasal obstruction, thirst and liking drink, the tip of the tongue side are red, the thin white micro- Huang of tongue.Anemopyretic cold
It is more common in caused by summer and autumn, affection of exogenous wind-heat.The traditional Chinese medical science thinks that anemopyretic cold is to experience the exterior syndrome caused by the heresy of wind-heat.
1. general symptom
（1）Have a sore throat, with regard to pain, the usual yellow of phlegm or with black generally before cold symptoms.
（2）Flow dense tears, usual yellow.
（3）Tongue fur band point yellow, it is also possible to be white, tongue body is generally redder.
（4）Constipation.
（5）Body is warm, thirsty, vexed.
（6）Vein is usually rapid pulse or full pulse, and it is fast to be exactly pulse ratio normal.
2. children's wind-heat cold symptom
Children are mainly shown as fever weight, but cold afraid of the wind unobvious, and the turbid tears of nasal blockage stream are coughed low voice speaking, or have sticky Huang
Phlegm, headache, thirst and liking drink, the red, dry throat of pharynx or sufferings.Stool is dry, and urine is yellow, checks that visible tonsillotome is red and swollen, congestion of throat, tongue
Tongue is thin yellow or yellow thick, red tongue body, floating pulse and it is fast.
Common cold initial stage, the flu that many patients think slight need not be treated, and waited body voluntarily self-healing, can so be made on the contrary
Flu is dragged more long and more long, and what is had even can drag more serious and more serious, and exacerbation of once catching a cold, and patient will take in order to be able to rehabilitation as early as possible
The Western medicine of some anti-inflammations, or go to hospital to have an injection, but either Western medicine is still had an injection, although take effect quickly, but it is secondary
Effect is also big, is easy to produce drug resistance, harm patient body health if access times are more.Particularly with child patient, more
It can not use easily.Therefore, the traditional Chinese medicine oral liquid for the treatment of anemopyretic cold is as one of problem discussed warmly.
Through retrieval, we find as follows on the traditional Chinese medicine oral liquid pertinent literature for the treatment of anemopyretic cold：
Chinese patent, application number：201410371826.9, title：A kind of new cold oral liquid and preparation method thereof, it is open
(bulletin) number：104147134A, applies for (patent right) people：The First Affiliated Hospital of Henan University of Science and Technology, summary：The invention belongs to cure
A kind of medicine field, and in particular to cold oral liquid and preparation method thereof.The present invention in formula by adding schizonepeta, sweet wormwood, Huang
A kind of reed mentioned in ancient books, the root of kudzu vine, Swamp Mahogany Leaf and chlorpheniramine, can effectively play a part of clearing heat and detoxicating, resistance common cold virus.In the mistake of preparation
In journey the present invention will calculus bovis factitius, radix scutellariae, the root of kudzu vine and Swamp Mahogany Leaf extract after mixing can be effectively promoted active ingredient abundant
Fusion, and then fast treating flu.It will be mixed again with chlorpheniramine after schizonepeta and sweet wormwood concentration, and in the bar that temperature is 40-60 DEG C
1-1.2 hours are stood under part.
The content of the invention
It is an object of the invention to provide a kind of traditional Chinese medicine oral liquid and its production method for treating anemopyretic cold, this product takes effect
It hurry up, have no toxic side effect, preparation method is simple, be applicable crowd's scope wide.
To achieve these goals, production method of the invention is：
Treat the traditional Chinese medicine oral liquid of anemopyretic cold, it is characterised in that：It is prepared from the following raw materials in parts by weight：
Baeckea frutescen 5000-8000g；
Swamp Mahogany Leaf 5000-8000g；
Honeysuckle flower 100-200g；
Capsule of weeping forsythia 100-200g；
Sweet wormwood 100-200g；
Schizonepeta 100-200g；
Peppermint 100-200g；
Radix bupleuri 100-200g；
Pogostemon cablin 80-160g；
Folium artemisiae argyi 70-140g；
Balloonflower root 70-140g；
Dried orange peel 50-100g.
The optimum ratio of primary raw material is needed for 1000ml is often made in the traditional Chinese medicine oral liquid of the treatment anemopyretic cold of the present invention：
Baeckea frutescen 6818g, Swamp Mahogany Leaf 6818g, Honeysuckle flower 159g, capsule of weeping forsythia 136g, sweet wormwood 159g, schizonepeta 159g, peppermint 136g, radix bupleuri
136g, Pogostemon cablin 114g, folium artemisiae argyi 91g, balloonflower root 114g, dried orange peel 68g.
The production method of traditional Chinese medicine oral liquid of present invention treatment anemopyretic cold is：
1st, above-mentioned medicinal material is added water to cook three times, and 5~7 times of amount water of above-mentioned six kinds of medicinal material gross weights are added every time, are decocted for the first time
1.5 hours, respectively decocted 1 hour with third time for the second time, three decoction liquors filterings of merging, are that decoction is concentrated into phase by gained filtrate
It is 1.10~1.20 to density（Determined at 75~85 DEG C）；
2nd, alcohol is added after decoction is let cool makes the alcohol content of decoction reach 55%~65%, stands 10~12 hours, filters, reclaims
Alcohol, alcohol is added in remaining decoction makes the alcohol content of decoction reach 65%~75%, stands 10~12 hours, filtration,
Recovered alcohol, then it is 1.15~1.25 that remaining decoction is concentrated into relative density（Determined at 75~85 DEG C）；
3rd, 300~400ml water stirring is added in concentrated medicament, is boiled 10~12 minutes, 10~12 hours are stood, filtering,
1~2g of 100~200g of sucrose and agar is added, stirs evenly, adds 0.2~0.4g of ethyl-para-hydroxybenzoate, finally adds distillation
Water adjusts total amount to 1000ml, stirs evenly, filling, gland, and sterilizing can be prepared by product of the present invention.
The Chinese medicine of above-mentioned treatment anemopyretic cold can also add concentrated medicament appropriate medical accessory, and tablet, capsule is made
Or pellet product.
Medically research shows that the herbal component selected by the present invention has following effect：
Above-described baeckea frutescen【Alias】Card wood, besom branch, pine tag branch, snakeworm grass, Ji Ersong, fragrant bavin, broom, kwan-yin is swept to sweep
【Classification system】Baeckea frutescens L.,Bitter；It is pungent；It is cool in nature.Blood-activating analgetic；Heat-clearing unit of weight measurement, about six liang poison；Inducing diuresis for treating strangurtia；Desinsection
It is antipruritic.Cure mainly traumatic injury；Tripe is hardened；Heat is rushed down；Heat gonorrhea；Difficult urination；Pruritus vulvae；Tinea pedis；Eczema；Pruitus；Mange；Extreme misery
Scald；Worm snake bite.1.《Guangzhou flora》：Control pyreticosis.2.《Luchuan book on Chinese herbal medicine》：Detumescence, analgesic, stasis eliminatings, desinsection.Control bruise dusk
Fan, scabies, ulcer, snake bite.3.《Nanning City's medicine will》：Convergence, desinsection stops blooding, analgesic, myogenic.With washing sore, itch.
4.《Guangxi Chinese medicinal herbal》：There is diuresis promoting effect.Control bladder heat, difficult urination, pruritus vulvae, skin hot gas.Decoct washing skin it is rotten itch,
Eczema；Leaf, smashes deposited, controls centipede wound, and branches and leaves, steam oil controls sore leprosy etc..
Above-described Swamp Mahogany Leaf【Classification system】Eucalyptus robusta Smith.【Alias】Folium eucalypti【Nature and flavor】
It is pungent；It is bitter；It is cool in nature【Major function】Dispelling wind is delivered；Expelling phlegm and arresting coughing；It is clearing heat and detoxicating；Desinsection is antipruritic.Main flu；Hyperpyrexia closes pain；Lung
Heat panting is coughed；Diarrhea dysentery abdominal pain；Malaria；Arthralgia pain due to rheumatism；Filariasis；Leptospirosis；Abscess of throat；Hot eyes；Ocular；Ear carbuncle；It is red
Poison；Ulcer；Acute mastitis；Measles；Rubella；Eczema；Mange；Scald,【Each discussion】1.《Middle traditional Chinese medicines plant illustrated handbook》：Control suppurative wound
Wound, refractory ulcer etc..2.《South of the Five Ridges herbal》：Dispelling wind is antipyretic, and anti-corrosion is antipruritic.3.《Guangxi Chinese herbal medicine》：It is clearing heat and detoxicating, desinsection
Convergence.Control diarrhoea, dysentery, flu, malignant boil ulcerative carbuncle furuncle and eczema.4.《Zhejiang conventional herbal medicine among the people》：Cough-relieving, stomach invigorating, expelling parasite.
Above-described Honeysuckle flower is caprifoliaceae plant largeflower-like honeysuckle flower, lonicera hypoglauca miq, Lonicera confusa or fulvoushair honeysuckle flower
Dry flower or with the flower just opened.It is born under small stream side, wilderness sparse woods or in bushes.Originate in south China various regions.Nature and flavor are returned
Through：It is sweet, tremble with fear.Return lung, the heart, stomach.【Classification system】Lonicera hypoglauca,【Alias】Mountain flower, southern honeysuckle flower, mountain gold honeysuckle flower,
Native honeysuckle, wild honeysuckle etc.,【Effect】It is clearing heat and detoxicating, dispelling wind and heat from the body.For carbuncle swells treat sore, larynx numbness, erysipelas, toxic-heat and blood stasis,
Anemopyretic cold, warm morbidity.
The above-described capsule of weeping forsythia【Classification system】Forsythia suspensa,【Alias】Chrysanthemum bar, even shell, green grass or young crops stick up, fallen
Stick up, Huang Qidan,【Nature and flavor】Hardship, it is cool.①《This warp》：Bitter, puts down.②《Do not record》：It is nontoxic.③《Medicine origin》：《Cure mainly secret formula》
Cloud, cool in nature, bitter.④《Detailed outline》：Slight bitter is pungent.【Channel tropism】Enter the heart, liver, gallbladder channel.①《The Decoction and Material Medica》：The few sun of brothers, Yangming Channel.
②《Detailed outline》：Few the moon the heart channel of Hang-Shaoyin, Yinpao (Liv 9) network qi leel of fainting.③《Thunder God processes property of medicine solution》：Enter the heart, liver, courage, stomach, three burnt, large intestines six
Through.【Major function】Heat-clearing, removing toxic substances, dissipating bind, detumescence.Control warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes.
Above-described sweet wormwood, is feverfew sweet wormwoodArtemisia annua L.Dry aerial parts.【Latin
Name】Artemisia carvifolia,【Also known as】Careless wormwood artemisia, granary wormwood artemisia, Artemisia capillaris, evil wormwood artemisia, abrotanum, apple wormwood artemisia, black wormwood artemisia, Bai Rangen is bitter
Wormwood artemisia,【Nature and flavor and channel tropism】：Hardship, it is pungent, tremble with fear.Return liver, gallbladder channel, three burnt, kidney channels.【Major function】Clear abnormal heat, cool blood is solved except steaming
Heat, preventing malaria.For summer-heat evil heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to yin labor heat, malaria fever and chills, jaundice with damp-heat pathogen.The product bitter cold is clear
Heat, it is pungent fragrant thoroughly scattered, it is kind to make cloudy point of latent heat thoroughly up to outer scattered, it is fever due to yin deficiency key medicine, has relieving summer-heat concurrently in addition, cuts cruel work(.1, relieving summer-heat：
Diseases caused by external factors hot summer weather can be controlled, polydipsia of generating heat.2, cut cruel：Cure mainly fevers and chills alternate caused by malaria.3, cool blood, reducing the asthenic fever：It is kind to control deficiency of Yin hair
Heat, hectic fever due to yin labor heat, and warm heat disease later stage, heat enters cloudy point, night fever abating at dawn person.
Above-described schizonepeta,【Alias】Fragrant chaste tree shepherd's purse, line shepherd's purse, four rib bar wormwood artemisias, false Soviet Union, are that Labiatae, Nepeta are perennial
Plant.【Classification system】Nepeta cataria L.,Schizonepeta is sweating, alexipyretic, is one of conventional herbal medicine of China, can town phlegm,
Wind-dispelling, cool blood.Control influenza, headache fever and chills sweating, vomiting.【Nature and flavor】It is pungent；Slight bitter；Slightly warm in nature.1、《This warp》：It is pungent,
Temperature.2、《Medicine origin》：Temperature, pungent hardship,【Channel tropism】Enter lung, Liver Channel.1、《Detailed outline》：Enter meridian of Foot-JUE YIN qi leel.2、《Thunder God big gun
Pharmacy solution》：Enter lung, the warp of liver two.3、《Collected statements on the herbal foundation》：Foot is fainted cloudy, few sun, Yangming Channel.【Effect】Wind-dispelling；Inducing diaphoresis；Thoroughly
Rash；Hemostasis.Main cold, fever；Headache；Eye itching；Cough；Abscess of throat；Measles；Carbuncle swells；Sore scabies；Bleeding from five sense organs or subcutaneous tissue；Spit blood；Have blood in stool；Collapse
Leakage；Postpartum anemic fainting.For catching a cold, headache, measles, rubella, sore from the beginning of.Fry charcoal treating hematochezia, uterine bleeding, postpartum anemic fainting.Inducing diaphoresis dissipates
Wind, promoting eruption, disappear sore, hemostasis.For catching a cold, measles without adequate eruption, have blood in stool, uterine bleeding, nosebleed epistaxis.
Above-described peppermint, is Labiatae mint peppermint Mentha haplocalyx Briq.Dry ground
Upper part.【Alias】Thin severe（《A thousand pieces of gold food therapy》）, greenbrier Lin, Wu greenbrier Lin（《Feeding habits book on Chinese herbal medicine》）, southern peppermint（《Amplification on Materia Medica》）,
Cat is thin severe（《Lv Cliff rocks book on Chinese herbal medicine》）, rising Yang dish（《The southern regions of the Yunnan Province book on Chinese herbal medicine》）, it is thin severe（《Product converge essence will》）, Bo lotuses（《Book on Chinese herbal medicine covers bamboo fish trap》）,
Night breath flower（《Plant name converges》）.【Nature and flavor】It is pungent, it is cool.【Channel tropism】Return lung, Liver Channel.【Major function】Dispelling wind-heat.Refresh oneself, thoroughly
Rash.For anemopyretic cold, wind-warm syndrome is from the beginning of headache, hot eyes, larynx numbness, aphtha, rubella, measles, Breast bilges frowsty about.
Above-described radix bupleuri,【Alias】Ground is smoked, mountain dish, mushroom grass, faggot, bitter in taste, be slightly cold, Return liver, gallbladder channel.There is reconciliation
In table, the effect of soothing the liver rising Yang.Taken off for cold, fever, fevers and chills alternate, malaria, stagnation of QI due to depression of the liver, sternal rib pain, prolapse of the anus, uterus
Vertical, irregular menstruation.This product is umbelliferae bupleurumBupleurum chinense DC.Or radix bupleuri scorzoneraefoliiBupleurum scorzonerifolium WilldDry root.【Character】Bupleurum Chinese：In cylinder or conico-acuminate, long 6~15cm, directly
0.3~0.8cm of footpath.Root head expands, and top remains 3~15 stem foots or chopped fiber shape phyllopodium, bottom branch.Surface dark brown or
Light brown, tool vertical wrinkle, supporting root trace and hole skin.Matter is hard and tough, is not easily broken, and section shows fibroid, and skin zone's light brown, woody part is yellow
White.Gas micro-perfume, mildly bitter flavor.RADIX BUPLEURI SCORZONERAEFOLII：Root is thinner, and there are most furry dead leaf fibers on cone, top, not branch more than bottom
Or slightly branch.Surface rufous is dark brown, at root head more have fine and closely woven ring grain.Matter is slightly soft, and frangibility, section is slightly flat,
Do not show fibroid.Tool loses oil gas.【Nature and flavor】Hardship, is slightly cold.【Channel tropism】Return liver, gallbladder channel.【Major function】It is soothing the liver in inducing diaphoresis, rise
Sun.For cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, sub-official prolapses, prolapse of the anus.
Above-described Pogostemon cablin, is labiate Pogostemon cablin【Classification system】Pogostemon cablin （Blanco） Benth.Dry aerial parts.By the place of production difference point Stone steles Pogostemon cablin and Pogostemon cablin Benth.【Nature and flavor】It is pungent, it is micro-
Temperature.【Channel tropism】Returns spleen, stomach, lung channel.
【Major function】Eliminate dampness with aromatics, whet the appetite preventing or arresting vomiting, delivers relieving summer-heat.For turbi damp obstructing in middle-JIAO, gastral cavity ruffian is vomitted, summer-heat and damp burnout,
Uncomfortable in chest not relax, cold-dampness closes heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.
Above-described folium artemisiae argyi, is feverfew Chinese mugwort【Classification system】Artemisia argyi Levl. et Vant.
Dried leaf.【Nature and flavor】Pungent, hardship, temperature；It is slightly poisonous.【Channel tropism】Return liver, spleen, kidney channel.【Major function】Eliminating cold to stop pain, Wen Jingzhi
Blood.For few abdomen crymodynia, through uncomfortable, uterus cold infertile of trembling with fear, spit blood, bleeding from five sense organs or subcutaneous tissue, uterine bleeding passes through many, gestation hemorrhage；Control pruitus outside.Vinegar
End charcoal warming channel for arresting bleeding.For deficient cold type bleeding.
Above-described balloonflower root.For Campanulaceae balloonflower root【Classification system】Platycodon grandiflorum （Jacq.）A.DC. dry root.【Nature and flavor】It is bitter, pungent, put down.【Channel tropism】Return lung is passed through.【Major function】Facilitaing lung, relieving sore-throat, eliminating the phlegm, row
Purulence.For coughing with a lot of sputum, uncomfortable in chest not smooth, pharyngalgia, sound is mute, lung carbuncle pyemesis, and sore purulence is not into bursting.
Above-described dried orange peel, is rutaceae orange【Classification system】Citrus reticulata BlancoAnd its
The dry mature skin of variety.Medicinal material is divided into " dried orange peel " and " citrus chachiensis hortorum ".【Nature and flavor】It is bitter, pungent, temperature.【Channel tropism】Return lung, spleen
Through.【Major function】Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For chest gastral cavity turgor, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
The pharmacological function of each composition is in the present invention：
Baeckea frutescen blood-activating analgetic, heat-clearing unit of weight measurement, about six liang poison；Swamp Mahogany Leaf dispelling wind is delivered, and expelling phlegm and arresting coughing is clearing heat and detoxicating；Honeysuckle flower is clearing heat and detoxicating,
Dispelling wind and heat from the body；Capsule of weeping forsythia heat-clearing, removing toxic substances, dissipating bind；The clear abnormal heat of sweet wormwood, cool blood is except steaming, relieving summer-heat, preventing malaria；Schizonepeta expels pathogenic wind from the body surface；Peppermint
Dispelling wind-heat；It is soothing the liver in radix bupleuri and inducing diaphoresis, rising Yang；Pogostemon cablin is eliminated dampness with aromatics, and whet the appetite preventing or arresting vomiting；Folium artemisiae argyi eliminating cold to stop pain；Balloonflower root is declared
Lung, relieving sore-throat, eliminating the phlegm, apocenosis；Dried orange peel regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.
It is exactly a kind of traditional Chinese medicine oral liquid and its production method for treating anemopyretic cold above, production process flow is simple, most
Bigization retains the multiple efficacies being rich in various Chinese medicine materials.
Beneficial effects of the present invention：
Beneficial effect to patient is：Utilize baeckea frutescen, Swamp Mahogany Leaf, Honeysuckle flower, the capsule of weeping forsythia, sweet wormwood, schizonepeta, peppermint, radix bupleuri, wide
Itself effect of wrinkled giant hyssop, folium artemisiae argyi, balloonflower root, dried orange peel reach clearing heat and detoxicating, dispelling wind deliver, cooling blood and dissolving stasis, blood circulation and channel invigorating, clearing heat and promoting diuresis,
Removing toxicity for detumescence, so as to reach the purpose for the treatment of anemopyretic cold.Both be free from side effects compared to for Western medicine, but can go directly trouble institute and
Instant effect, can mitigate patient suffering to greatest extent.Beneficial effect to the producer is：It is simple to operate in manufacturing process, it is various
The source of Chinese herb is wide, cheap, and this also alleviates the financial burden of patient simultaneously.To the beneficial effect of Chinese medicine in itself
It is：Popularization and acceleration Chinese medicine preparation modernization of the present invention to Chinese medicine serve certain impetus.
Embodiment
Embodiment 1,
Take following raw material：
Baeckea frutescen 5000g；Swamp Mahogany Leaf 5000g；Honeysuckle flower 100g；Capsule of weeping forsythia 100g；Sweet wormwood 100g；Schizonepeta 100g；Peppermint 100g；Bavin
Hu 100g；Pogostemon cablin 80g；Folium artemisiae argyi 70g；Balloonflower root 70g；Dried orange peel 50g.
Production method is as follows：
1st, above-mentioned medicinal material is added water to cook three times, and 5~7 times of amount water of above-mentioned six kinds of medicinal material gross weights are added every time, are decocted for the first time
1.5 hours, respectively decocted 1 hour with third time for the second time, three decoction liquors filterings of merging, are that decoction is concentrated into phase by gained filtrate
It is 1.10~1.20 to density（Determined at 75~85 DEG C）；
2nd, alcohol is added after decoction is let cool makes the alcohol content of decoction reach 55%~65%, stands 10~12 hours, filters, reclaims
Alcohol, alcohol is added in remaining decoction makes the alcohol content of decoction reach 65%~75%, stands 10~12 hours, filtration,
Recovered alcohol, then it is 1.15~1.25 that remaining decoction is concentrated into relative density（Determined at 75~85 DEG C）；
3rd, 300~400ml water stirring is added in concentrated medicament, is boiled 10~12 minutes, 10~12 hours are stood, filtering,
1~2g of 100~200g of sucrose and agar is added, stirs evenly, adds 0.2~0.4g of ethyl-para-hydroxybenzoate, finally adds distillation
Water adjusts total amount to 1000ml, stirs evenly, filling, gland, and sterilizing can be prepared by product of the present invention.
Embodiment 2,
Take following raw material：
Baeckea frutescen 6818g；Swamp Mahogany Leaf 6818g；Honeysuckle flower 159g；Capsule of weeping forsythia 136g；Sweet wormwood 159g；Schizonepeta 159g；Peppermint 136g；Bavin
Hu 136g；Pogostemon cablin 114g；Folium artemisiae argyi 91g；Balloonflower root 114g；Dried orange peel 68g.
Production method is as follows：
1st, above-mentioned medicinal material is added water to cook three times, and 5~7 times of amount water of above-mentioned six kinds of medicinal material gross weights are added every time, are decocted for the first time
1.5 hours, respectively decocted 1 hour with third time for the second time, three decoction liquors filterings of merging, are that decoction is concentrated into phase by gained filtrate
It is 1.10~1.20 to density（Determined at 75~85 DEG C）；
2nd, alcohol is added after decoction is let cool makes the alcohol content of decoction reach 55%~65%, stands 10~12 hours, filters, reclaims
Alcohol, alcohol is added in remaining decoction makes the alcohol content of decoction reach 65%~75%, stands 10~12 hours, filtration,
Recovered alcohol, then it is 1.15~1.25 that remaining decoction is concentrated into relative density（Determined at 75~85 DEG C）；
3rd, 300~400ml water stirring is added in concentrated medicament, is boiled 10~12 minutes, 10~12 hours are stood, filtering,
1~2g of 100~200g of sucrose and agar is added, stirs evenly, adds 0.2~0.4g of ethyl-para-hydroxybenzoate, finally adds distillation
Water adjusts total amount to 1000ml, stirs evenly, filling, gland, and sterilizing can be prepared by product of the present invention.
Embodiment 3,
Take following raw material：Baeckea frutescen 8000g；Swamp Mahogany Leaf 8000g；Honeysuckle flower 200g；Capsule of weeping forsythia 200g；Sweet wormwood 200g；Schizonepeta 200g；
Peppermint 200g；Radix bupleuri 200g；Pogostemon cablin 160g；Folium artemisiae argyi 140g；Balloonflower root 140g；Dried orange peel 100g.
Production method is as follows：
1st, above-mentioned medicinal material is added water to cook three times, and 5~7 times of amount water of above-mentioned six kinds of medicinal material gross weights are added every time, are decocted for the first time
1.5 hours, respectively decocted 1 hour with third time for the second time, three decoction liquors filterings of merging, are that decoction is concentrated into phase by gained filtrate
It is 1.10~1.20 to density（Determined at 75~85 DEG C）；
2nd, alcohol is added after decoction is let cool makes the alcohol content of decoction reach 55%~65%, stands 10~12 hours, filters, reclaims
Alcohol, alcohol is added in remaining decoction makes the alcohol content of decoction reach 65%~75%, stands 10~12 hours, filtration,
Recovered alcohol, then it is 1.15~1.25 that remaining decoction is concentrated into relative density（Determined at 75~85 DEG C）；
3rd, 300~400ml water stirring is added in concentrated medicament, is boiled 10~12 minutes, 10~12 hours are stood, filtering,
1~2g of 100~200g of sucrose and agar is added, stirs evenly, adds 0.2~0.4g of ethyl-para-hydroxybenzoate, finally adds distillation
Water adjusts total amount to 1000ml, stirs evenly, filling, gland, and sterilizing can be prepared by product of the present invention.
Embodiment 4, treats the Chinese medicinal tablet production method of anemopyretic cold
Main raw materials in proportion is：Baeckea frutescen 6818g, Swamp Mahogany Leaf 6818g, Honeysuckle flower 159g, capsule of weeping forsythia 136g, sweet wormwood 159g, schizonepeta
159g, peppermint 136g, radix bupleuri 136g, Pogostemon cablin 114g, folium artemisiae argyi 91g, balloonflower root 114g, dried orange peel 68g.
Production method is as follows：
1st, above-mentioned medicinal material is added water to cook three times, and 5~7 times of amount water of above-mentioned six kinds of medicinal material gross weights are added every time, are decocted for the first time
1.5 hours, respectively decocted 1 hour with third time for the second time, three decoction liquors filterings of merging, are that decoction is concentrated into phase by gained filtrate
It is 1.10~1.20 to density（Determined at 75~85 DEG C）；
2nd, alcohol is added after decoction is let cool makes the alcohol content of decoction reach 55%~65%, stands 10~12 hours, filters, reclaims
Alcohol, alcohol is added in remaining decoction makes the alcohol content of decoction reach 65%~75%, stands 10~12 hours, filtration,
Recovered alcohol, then it is 1.15~1.25 that remaining decoction is concentrated into relative density（Determined at 75~85 DEG C）；
3rd, suitable auxiliary material such as inserts, disintegrant are added in concentrated medicament, you can tablet is made.
Product testing of the present invention
1 clinical data
1.1 general information
This data totally 50, wherein：Male 27, women 23；8~18 years old age person 5,19~60 years old person 745；Belong to
In traditional Chinese medical science cold patient.
1.2 diagnosis and case person's standard use State Administration of Traditional Chinese Medicine<Gynecology ＆ Pediatrics Dept. disease diagnoses curative effect inside and outside the traditional Chinese medical science
Standard>In about cold diagnostic criteria, be used as diagnostic criteria.Selection meets<Standard>The disease of middle cold diagnosis
Example, excludes endogenous cough and other non-exogenous diseaseses are led
Cold case, using Issued by China State Bureau of Technical Supervision<Tcm clinical practice diagnosis and treatment term syndrome part>It is used as dialectical mark
It is accurate.
1.3 clinical manifestation
This data 50, all has different degrees of headache, heating, aversion to cold, nasal obstruction, runny nose, cough, pharyngalgia and general malaise
It is characterized, visible nasal decongestion of having a medical check-up, oedema and more secretion, pharyngeal mild hyperaemia；Some pharyngalgia, red tip of tongue, tongue are thin
It is yellow.Meet preceding diagnosis and person's standard.
Treatment group and control group are randomly divided into by 50.Wherein treatment group 35, control group 15.
2.1 treatment method
(1) treatment group：Take cold drug.3 tablets once by adult, and 3 times a day, and children halve.
(2) control group：Oral liquid of the present invention is taken, is grown up 100 milliliters every time, 3 times a day.Children halve.
2.2 observation of curative effect（Slightly）
3. criterion of therapeutical effect
With reference to State Administration of Traditional Chinese Medicine<Gynecology ＆ Pediatrics Dept. disease Standardization of diagnosis and curative effect inside and outside the traditional Chinese medical science>[draw, carry out efficacy determination：①
It is effective：
Clinical sign disappears；2. take a turn for the better：Cold cough mitigates, and amount of expectoration is reduced；
3. it is invalid：Symptom is without improvement.
3.1 treatment results
Two groups of case comparitive studies are shown in Table 1.Two groups do not occur any toxicity.
3.2 toxicities, two groups of patients are showed no any toxicity in drug administration process.
Application Example：
Embodiment 1,
Zhang, 25 years old, teacher.One's spirits are drooping into day due to postpartum poor sleeping quality, poor appetite causes body drag to decline,
Nursing period has suffered from heavy cold, dare not medicine injection, drink upon somebody's introduction in April, 2016 embodiment of the present invention 1 oral liquid production
Product one week, throw off a cold, she is very satisfied to using effect.
Embodiment 2,
Mr. Li, 28 years old, office's white collar.Miss Li suffers from thermal sensation in mid-April, 2016, and dry cough is serious, or even air-breathing is all
Cough.Do not felt any better still within five days from Western medicine is taken, the oral liquid product one week for drinking the embodiment of the present invention 2 is introduced by friend, felt
Recovery from illness is emitted, cough symptom is considerably reduced, adhere to that cough symptom disappears after two weeks, she is very satisfied with to using effect.
Embodiment 3,
Mr. Wang, 8 years old, the Mr. Wang dry pain of itching of throat in by the end of May, 2016, slight illness, finally suffers from thermal sensation, all day long in the near future
Drowsy, headache is endlessly.The oral liquid of the embodiment of the present invention 3 is drunk after being introduced one week, throat recovery from illness headache symptom disappears
Lose, body recovery from illness.
Claims (4)
1. a kind of traditional Chinese medicine oral liquid for treating anemopyretic cold, it is characterised in that：It is prepared from the following raw materials in parts by weight：
Baeckea frutescen 5000-8000g；
Swamp Mahogany Leaf 5000-8000g；
Honeysuckle flower 100-200g；
Capsule of weeping forsythia 100-200g；
Sweet wormwood 100-200g；
Schizonepeta 100-200g；
Peppermint 100-200g；
Radix bupleuri 100-200g；
Pogostemon cablin 80-160g；
Folium artemisiae argyi 70-140g；
Balloonflower root 70-140g；
Dried orange peel 50-100g.
2. the traditional Chinese medicine oral liquid for the treatment of anemopyretic cold according to claim 1, it is characterised in that：Often it is made needed for 1000ml
The proportioning of primary raw material is：
Baeckea frutescen 6818g；
Swamp Mahogany Leaf 6818g;
Honeysuckle flower 159g;
Capsule of weeping forsythia 136g;
Sweet wormwood 159g;
Schizonepeta 159g;
Peppermint 136g;
Radix bupleuri 136g;
Pogostemon cablin 114g;
Folium artemisiae argyi 91g;
Balloonflower root 114g;
Dried orange peel 68g.
3. the traditional Chinese medicine oral liquid for the treatment of anemopyretic cold according to claim 1 or 2, it is characterised in that：Its production method bag
Include following steps：
（1）, above-mentioned medicinal material add water to cook three times, 5~7 times of above-mentioned six kinds of medicinal material gross weights amount water are added every time, are decocted for the first time
Boil 1.5 hours, respectively decocted 1 hour with third time for the second time, three decoction liquors filterings of merging, are that decoction is concentrated into by gained filtrate
Relative density is 1.10~1.20；
（2）, decoction is let cool after add alcohol and the alcohol content of decoction is reached 55%~65%, stand 10~12 hours, filter, return
Alcohol is received, alcohol is added in remaining decoction makes the alcohol content of decoction reach 65%~75%, stands 10~12 hours, filter
Cross, recovered alcohol, then it is 1.15~1.25 that remaining decoction is concentrated into relative density；
（3）, in concentrated medicament add 300~400ml water stirring, boil 10~12 minutes, stand 10~12 hours, mistake
Filter, adds 1~2g of 100~200g of sucrose and agar, stirs evenly, add 0.2~0.4g of ethyl-para-hydroxybenzoate, finally adds and steams
Distilled water adjusts total amount to 1000ml, stirs evenly, filling, gland, and sterilizing can be prepared by product of the present invention.
4. the traditional Chinese medicine oral liquid of the treatment anemopyretic cold for the treatment of digestive discomfort according to claim 3, it is characterised in that：Also
Concentrated medicament can be added to appropriate medical accessory, tablet, capsule or pill is made.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181393A (en) * | 2007-11-22 | 2008-05-21 | 张树球 | Chinese medicine preparation for curing common cold and producing method thereof |
| CN106474222A (en) * | 2016-10-27 | 2017-03-08 | 金秀瑶族自治县瑶医医院 | There are precious jade medicine medicine for external use bath preparations of the anti-effect that cures cold and preparation method thereof |
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2017
- 2017-06-07 CN CN201710421590.9A patent/CN107260849A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181393A (en) * | 2007-11-22 | 2008-05-21 | 张树球 | Chinese medicine preparation for curing common cold and producing method thereof |
| CN106474222A (en) * | 2016-10-27 | 2017-03-08 | 金秀瑶族自治县瑶医医院 | There are precious jade medicine medicine for external use bath preparations of the anti-effect that cures cold and preparation method thereof |
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