CN107224415A - Primary ferment compacts Face-protecting mask - Google Patents
Primary ferment compacts Face-protecting mask Download PDFInfo
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- CN107224415A CN107224415A CN201710430871.0A CN201710430871A CN107224415A CN 107224415 A CN107224415 A CN 107224415A CN 201710430871 A CN201710430871 A CN 201710430871A CN 107224415 A CN107224415 A CN 107224415A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Dermatology (AREA)
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Abstract
Compacted Face-protecting mask, including raw material the invention provides a kind of primary ferment:Butanediol, glycerine, Tremella fructification extract, saccharomycetes to make fermentation product, Gotu Kola P.E, ginseng root extract, Baical Skullcap root P.E, Sodium Hyaluronate, Flos Rosae Rugosae extract, glycine betaine, biological carbohydrate gum 1, licorice, peony root extractive.The primary ferment of the present invention compacts Face-protecting mask while the nutrient of facial skin is given, in time the absorbing path of the aquaporin of dredging skin and nutrient, allows the skin-care effect of facial mask to double lifting.Compacted present invention also offers a kind of primary ferment the preparation method of Face-protecting mask.
Description
Technical field
The present invention relates to daily cosmetics field, and in particular to a kind of primary ferment compacts Face-protecting mask.
Background technology
With present expanding economy, work, the rhythm lived are also increasingly faster, and people's spirit pressure is also increasing,
Necessary protection is not taken plus bad habits and customs, and facial skin, easily causes facial skin by extraneous ring
Border, such as ultraviolet, haze particle, dry air, the influence of cold gas, increasing people are dried, slightly by facial skin
The problem of skins such as rough, pore is thick, dim mute, the whole face small pox of the colour of skin are disorderly is perplexed, and even results in cutis laxa, growth
Microgroove.Therefore, increasing people starts to pay attention to the nursing of facial skin, and people are also more and more vigorous to the demand of facial mask, repair
Shield class facial mask has a extensive future.
Occur in that on the market in recent years it is many claim to the facial masks that facial skin is repaired in nursing, it is but many to mend as principle
And develop, effect is single, simple moisturizing or simple maintenance, the reception nutritional ingredient of skin passively.But in fact, simple moisturizing
Obviously maintenance that can not be enough to skin progress and nutritional supplementation, and the battalion that simple Face-protecting mask is wherein not yet absorbed by the skin
Support to be excluded in time, normally breathing and the circulation of influence skin, and skin burden is aggravated on the contrary.
The content of the invention
The problem of existing for prior art, compacts Face-protecting mask the invention provides a kind of primary ferment, gives face
While the nutrient of skin, the absorbing path of the aquaporin of dredging skin and nutrient, allows the skin-care effect of facial mask to add in time
Lifted again.
To achieve the above object, primary ferment of the invention compacts Face-protecting mask including raw material:Butanediol, glycerine, white fungus
Fruiting body extract, saccharomycetes to make fermentation product, Gotu Kola P.E, ginseng root extract, Baical Skullcap root P.E, Sodium Hyaluronate,
Flos Rosae Rugosae extract, glycine betaine, biological carbohydrate gum -1, licorice, peony root extractive.
Further, in the raw material of facial mask, butanediol 2-6 parts by weight, glycerine 1-5 parts by weight, Tremella fructification are extracted
Thing 1-5 parts by weight, saccharomycetes to make fermentation product 1-5 parts by weight, Gotu Kola P.E 0.5-3 parts by weight, ginseng root extract 1-5 weights
Measure part, Baical Skullcap root P.E 0.1-3 parts by weight, Sodium Hyaluronate 0.03-0.1 parts by weight, Flos Rosae Rugosae extract 1-5 parts by weight, sweet tea
Dish alkali 0.5-3 parts by weight, biological carbohydrate gum -1 are 0.5-2 parts by weight, licorice 0.1-1 parts by weight, peony root extractive
0.1-0.5 parts by weight.
Further, the parts by weight of raw material are as follows:The parts by weight of Tremella fructification extract 3, the weight of saccharomycetes to make fermentation product 3
Measure part, the parts by weight of Gotu Kola P.E 2, the parts by weight of ginseng root extract 3, the parts by weight of Baical Skullcap root P.E 1.5, Flos Rosae Rugosae extract
3 parts by weight, the parts by weight of licorice 0.5.
Selectively, the parts by weight of raw material are as follows:The parts by weight of Tremella fructification extract 1, the weight of saccharomycetes to make fermentation product 1
Measure part, the parts by weight of Gotu Kola P.E 0.5, the parts by weight of ginseng root extract 1, the parts by weight of Baical Skullcap root P.E 0.5, rose extraction
The parts by weight of thing 1, the parts by weight of licorice 0.1.
Selectively, the parts by weight of raw material are as follows:The parts by weight of Tremella fructification extract 2, the weight of saccharomycetes to make fermentation product 2
Measure part, the parts by weight of Gotu Kola P.E 1, the parts by weight of ginseng root extract 2, the parts by weight of Baical Skullcap root P.E 1, Flos Rosae Rugosae extract 2
Parts by weight, the parts by weight of licorice 0.3.
Selectively, the parts by weight of raw material are as follows:The parts by weight of Tremella fructification extract 4, the weight of saccharomycetes to make fermentation product 4
Measure part, the parts by weight of Gotu Kola P.E 1.5, the parts by weight of ginseng root extract 4, the parts by weight of Baical Skullcap root P.E 1.5, rose extraction
The parts by weight of thing 4, the parts by weight of licorice 0.8.
Selectively, the parts by weight of raw material are as follows:The parts by weight of Tremella fructification extract 5, the weight of saccharomycetes to make fermentation product 5
Measure part, the parts by weight of Gotu Kola P.E 4, the parts by weight of ginseng root extract 5, the parts by weight of Baical Skullcap root P.E 5, Flos Rosae Rugosae extract 6
Parts by weight, the parts by weight of licorice 1.
Further, the raw material of facial mask also includes:Water and matrix components, wherein matrix components include odorant, preservative,
Solubilizer, thickener, auxiliary skin quality conditioner.
Further, in the raw material of facial mask, matrix components are 0.5-3 parts by weight.
Compacted present invention also offers a kind of above-mentioned primary ferment the preparation method of Face-protecting mask, including:First polypropylene
Sour sodium, methyl hydroxybenzoate, Sodium Hyaluronate, it is heated to 80-85 DEG C, homogeneous 3 minutes is cooled to after 45 DEG C and adds remaining component, often
Add after a component, next component is added after stirring, adds and discharging is stirred to normal temperature after all raw materials.
In raw material of the present invention:
Tremella fructification extract:Can moment deep moisturizing, increase skin elasticity and tension force, help recovery skin normally oily
Water balance, improves and dries and relaxation skin, reduce wrinkle of skin, improve skin elasticity, improve dermatoglyph degree, moreover it is possible to strengthen skin
The prolonged water holding capacity of skin, can help elastic fibers and collagen to be in the environment full of moisture, allow what skin showed
It is more flexible.
Saccharomycetes to make fermentation product:The metabolism of cell can be strengthened, skin cell is in vitality when being employed prosperous
Sheng state, accelerates the renewal speed of cell, promotes the verification of skin collagen tissue, so as to reduce the wrinkle of skin, strengthens skin
Elasticity.
Gotu Kola P.E:Can be compacted epidermis and corium coupling part, skin can be made to limber up, and help to solve skin
Relaxation (especially postpartum mother), makes skin smooth flexible;Help promotes collagen in skin corium to be formed, and makes fiber egg
White regeneration, reconnect is got up, is inherently eliminated mother's line, skin is reached smooth effect of compacting.Also assist in impaired
Organization healing and consolidation skin.
Ginseng root extract:Elastoser and collagenase activity can be suppressed, stimulated circulation, enhancing is immune
Power, promotes fibroblast proliferation, and anti-inflammatory enhances metabolism.
Baical Skullcap root P.E:The activity of TYR enzyme can be suppressed, suppress the formation of melanin, skin whitening can also suppress
The release of histamine, skin of releiving.
Flos Rosae Rugosae extract:Can have to skin cell tissue convergence, it is anti-oxidant, pacify, promote wound healing, it is moist etc.
Effect.
Biological carbohydrate gum -1:Long-time use can have to skin moisture-keeping, lubrication and wrinkle resistant effect.
Licorice:With anti-inflammatory is anti-, aging effect.
Peony root extractive:Effect with anti-oxidant well and skin care.
Butanediol, glycerine:It is respectively provided with the water conservation moisture-keeping function to facial skin.
The present invention primary ferment compact Face-protecting mask raw material composition in synergy is collocated with each other using each component, its
Proportioning is strictly controlled, and promotes impaired facial skin cells organized renewing regeneration, is being dredged the aquaporin of skin and is being supported
Divide absorbing path, while giving facial skin sufficient nutrient, can strengthen after facial skin reparation, Cucumber Extract strengthens skin
Metabolism, makes skin reach that good skin care is moistened and repair.
Embodiment
With reference to specific embodiment, the present invention is further elaborated and explanation.
Embodiment 1:A kind of primary ferment is compacted Face-protecting mask, and by percentage to the quality, its component is included:Tremella fructification
Extract 3%, saccharomycetes to make fermentation product 3%, Gotu Kola P.E 2%, ginseng root extract 3%, Baical Skullcap root P.E 1.5%,
Sodium Hyaluronate 0.05%, Flos Rosae Rugosae extract 3%, glycine betaine 0.5%, biological carbohydrate gum -1 are 1.5%, licorice
0.5%th, peony root extractive 0.3%, butanediol 5%, glycerine 2%, glycerin polyether -26 be 1%, Natrulon H-10 be 1%, it is pungent
Glycol 0.1%, Bis(hydroxymethyl)imidazolidinyl urea 0.1%, Sodium Polyacrylate 0.1%, p- anisic acids 0.05%, methyl hydroxybenzoate
0.1%th, water 72.2%.
The preparation method of embodiment 1 is:First Sodium Polyacrylate, methyl hydroxybenzoate, Sodium Hyaluronate is heated to 80-85 and taken the photograph
Family name's degree, homogeneous 3 minutes is cooled to addition material left each component after 45 degrees Celsius, and often adds after a component, to stir
Next component is just added after uniform, adds and discharging is stirred to normal temperature after all material, and is arrived by every 25 grams of weight is canned
Seal stand-by in facial mask bag.
Example 2 is to example 5:
By the Tremella fructification extract specified in table 1 below, saccharomycetes to make fermentation product, Gotu Kola P.E, ginseng
Extract, Baical Skullcap root P.E, Flos Rosae Rugosae extract, licorice and other skin quality conditioning agent content repeat EXPERIMENTAL EXAMPLE 1
Method, respectively obtain the plant enzyme oil control and acne removal mask product of different component, due to water and basic NMF, preservative,
Thickener, etc. auxiliary material on product efficacy almost without influence, therefore, without illustrating one by one in this formula:
Table 1:
Skin quality conditioner component | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 |
Tremella fructification extract | 1% | 2% | 4% | 5% |
Saccharomycetes to make fermentation product | 1% | 2% | 4% | 5% |
Gotu Kola P.E | 0.5% | 1% | 1.5% | 3% |
Ginseng root extract | 1% | 2% | 4% | 5% |
Baical Skullcap root P.E | 0.5% | 1% | 1.5% | 3% |
Flos Rosae Rugosae extract | 1% | 2% | 4% | 5% |
Licorice | 0.1% | 0.3% | 0.8% | 1% |
Obtain | Product 2 | Product 3 | Product 4 | Product 5 |
The preparation method of product into embodiment 5 of embodiment 2 is consistent with the preparation method of product 1 in embodiment 1.
By example 1, into example 5, obtained primary ferment compacts Face-protecting mask product, with existing Face-protecting mask production of compacting
Product carry out clinical trial contrast, and clinical trial condition is:50 women of volunteer, age 18-35 Sui, are used 1 time daily, the
One week was continuously used daily, and 28 days are continued using once every three days after second week.Experimental result is as shown in table 2:
Table 2:
Test event | Reference product | Product 1 | Product 2 | Product 3 | Product 4 | Product 5 |
Skin water content | Improve 26% | Improve 35% | Improve 20% | Improve 30% | Improve 40% | Improve 41% |
Skin brightness | Improve 28% | Improve 39% | Improve 26% | Improve 40% | Improve 45% | Improve 45% |
Skin sophistication | Improve 13% | Improve 35% | Improve 10% | Improve 26% | Improve 40% | Improve 43% |
Elasticity of skin | Improve 15% | Improve 32% | Improve 25% | Improve 30% | Improve 45% | Improve 48% |
In summary data, compared with the existing product to compare, by using the embodiment of the present invention 1, embodiment 3,
Embodiment 4, the product 1 of embodiment 5, product 3, product 4, after a period of time of product 5, the skin of facial mask user contains in skin
The production of embodiment 2 is greatly improved and used in terms of water, skin brightness, skin sophistication and elasticity of skin
After the same time of product 2, although in terms of skin water content, skin brightness, skin sophistication compared with existing product slightly
It is not so good as, but is lifted very greatly in terms of elasticity of skin, it is with the obvious advantage in terms of delaying skin microgroove grows, improves skin health degree,
And because active constituent content is relatively low, its cost is greatly reduced.
Only the preferred embodiment of the present invention is described for above-mentioned embodiment, and the not guarantor to the present invention
Shield scope is defined.On the premise of design concept of the present invention and scope is not departed from, one of ordinary skill in the art
, all should according to various modifications, replacement and improvement of the word description provided by the present invention to made by technical scheme
Belong to the protection category of the present invention.Protection scope of the present invention is determined by claim.
Claims (10)
- The Face-protecting mask 1. a kind of primary ferment compacts, it is characterised in that the raw material of the facial mask includes:Butanediol, glycerine, white fungus Fruiting body extract, saccharomycetes to make fermentation product, Gotu Kola P.E, ginseng root extract, Baical Skullcap root P.E, Sodium Hyaluronate, Flos Rosae Rugosae extract, glycine betaine, biological carbohydrate gum -1, licorice, peony root extractive.
- The Face-protecting mask 2. primary ferment as claimed in claim 1 compacts, it is characterised in that in the raw material of the facial mask, fourth two Alcohol 2-6 parts by weight, glycerine 1-5 parts by weight, Tremella fructification extract 1-5 parts by weight, saccharomycetes to make fermentation product 1-5 parts by weight, Gotu Kola P.E 0.5-3 parts by weight, ginseng root extract 1-5 parts by weight, Baical Skullcap root P.E 0.1-3 parts by weight, hyaluronic acid Sodium 0.03-0.1 parts by weight, Flos Rosae Rugosae extract 1-5 parts by weight, glycine betaine 0.5-3 parts by weight, biological carbohydrate gum -1 are 0.5-2 weights Measure part, licorice 0.1-1 parts by weight, peony root extractive 0.1-0.5 parts by weight.
- The Face-protecting mask 3. primary ferment as claimed in claim 2 compacts, it is characterised in that the parts by weight of raw material are as follows:White fungus The parts by weight of fruiting body extract 3, the parts by weight of saccharomycetes to make fermentation product 3, the parts by weight of Gotu Kola P.E 2, the weight of ginseng root extract 3 Measure part, the parts by weight of Baical Skullcap root P.E 1.5, the parts by weight of Flos Rosae Rugosae extract 3, the parts by weight of licorice 0.5.
- The Face-protecting mask 4. primary ferment as claimed in claim 2 compacts, it is characterised in that the parts by weight of raw material are as follows:White fungus The parts by weight of fruiting body extract 1, the parts by weight of saccharomycetes to make fermentation product 1, the parts by weight of Gotu Kola P.E 0.5, ginseng root extract 1 Parts by weight, the parts by weight of Baical Skullcap root P.E 0.5, the parts by weight of Flos Rosae Rugosae extract 1, the parts by weight of licorice 0.1.
- The Face-protecting mask 5. primary ferment as claimed in claim 2 compacts, it is characterised in that the parts by weight of raw material are as follows:White fungus The parts by weight of fruiting body extract 2, the parts by weight of saccharomycetes to make fermentation product 2, the parts by weight of Gotu Kola P.E 1, the weight of ginseng root extract 2 Measure part, the parts by weight of Baical Skullcap root P.E 1, the parts by weight of Flos Rosae Rugosae extract 2, the parts by weight of licorice 0.3.
- The Face-protecting mask 6. primary ferment as claimed in claim 2 compacts, it is characterised in that the parts by weight of raw material are as follows:White fungus The parts by weight of fruiting body extract 4, the parts by weight of saccharomycetes to make fermentation product 4, the parts by weight of Gotu Kola P.E 1.5, ginseng root extract 4 Parts by weight, the parts by weight of Baical Skullcap root P.E 1.5, the parts by weight of Flos Rosae Rugosae extract 4, the parts by weight of licorice 0.8.
- The Face-protecting mask 7. primary ferment as claimed in claim 2 compacts, it is characterised in that the parts by weight of raw material are as follows:White fungus The parts by weight of fruiting body extract 5, the parts by weight of saccharomycetes to make fermentation product 5, the parts by weight of Gotu Kola P.E 4, the weight of ginseng root extract 5 Measure part, the parts by weight of Baical Skullcap root P.E 5, the parts by weight of Flos Rosae Rugosae extract 6, the parts by weight of licorice 1.
- The Face-protecting mask 8. primary ferment as claimed in claim 1 compacts, it is characterised in that the raw material of the facial mask also includes: Water and matrix components, wherein the matrix components include odorant, preservative, solubilizer, thickener, auxiliary skin quality conditioner.
- The Face-protecting mask 9. primary ferment as claimed in claim 8 compacts, it is characterised in that in the raw material of the facial mask, institute Matrix components are stated for 0.5-3 parts by weight.
- The preparation method of Face-protecting mask 10. a kind of primary ferment as claimed in claim 1 compacts, it is characterised in that first poly- PAA, methyl hydroxybenzoate, Sodium Hyaluronate, it is heated to 80-85 DEG C, homogeneous 3 minutes is cooled to after 45 DEG C and adds remaining group Point, often add after a component, next component is added after stirring, adds and stirs to go out to normal temperature after all raw materials Material.
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Cited By (9)
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CN107496309A (en) * | 2017-10-23 | 2017-12-22 | 合肥卡迪尔化妆品有限公司 | Antiallergic Face-protecting mask |
CN108078860A (en) * | 2018-01-26 | 2018-05-29 | 武汉美格恩生物科技发展有限公司 | A kind of pollen pini face that shines is compacted Face-protecting mask liquid |
CN108158829A (en) * | 2018-01-18 | 2018-06-15 | 凌中鑫 | A kind of pectase facial mask cloth and its production method |
CN108721192A (en) * | 2018-09-06 | 2018-11-02 | 厦门洋妈制生物科技有限公司 | A kind of extracted form natural plant essence facial mask liquid and its extraction process |
CN110664700A (en) * | 2019-11-25 | 2020-01-10 | 广州赛莱拉生物基因工程有限公司 | Composition and application thereof in preparation of product for preventing and treating acne |
CN110812320A (en) * | 2019-12-14 | 2020-02-21 | 广州伊尔美生物科技有限公司 | Whitening and skin-protecting composition |
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Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107496309A (en) * | 2017-10-23 | 2017-12-22 | 合肥卡迪尔化妆品有限公司 | Antiallergic Face-protecting mask |
CN108158829A (en) * | 2018-01-18 | 2018-06-15 | 凌中鑫 | A kind of pectase facial mask cloth and its production method |
CN108078860A (en) * | 2018-01-26 | 2018-05-29 | 武汉美格恩生物科技发展有限公司 | A kind of pollen pini face that shines is compacted Face-protecting mask liquid |
CN108721192A (en) * | 2018-09-06 | 2018-11-02 | 厦门洋妈制生物科技有限公司 | A kind of extracted form natural plant essence facial mask liquid and its extraction process |
CN108721192B (en) * | 2018-09-06 | 2021-08-20 | 厦门洋妈制生物科技有限公司 | Natural plant extract essence facial mask liquid and extraction process thereof |
CN110664700A (en) * | 2019-11-25 | 2020-01-10 | 广州赛莱拉生物基因工程有限公司 | Composition and application thereof in preparation of product for preventing and treating acne |
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