CN107208067A - 新型肠侵袭性大肠杆菌噬菌体Esc‑COP‑4及其用于抑制肠侵袭性大肠杆菌增殖的用途 - Google Patents

新型肠侵袭性大肠杆菌噬菌体Esc‑COP‑4及其用于抑制肠侵袭性大肠杆菌增殖的用途 Download PDF

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CN107208067A
CN107208067A CN201580071157.6A CN201580071157A CN107208067A CN 107208067 A CN107208067 A CN 107208067A CN 201580071157 A CN201580071157 A CN 201580071157A CN 107208067 A CN107208067 A CN 107208067A
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coli
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尹成俊
姜尚铉
全秀娟
白亨琭
孙志洙
金炳局
申喜净
姜东珉
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Abstract

本发明涉及从自然界分离的并可以特异性地杀死肠侵袭性大肠杆菌菌株的肌尾噬菌体科噬菌体Esc‑COP‑4,其具有由SEQ ID NO:1的核苷酸序列表示的基因组(登记号:KCTC 12663BP),以及使用包含所述噬菌体作为活性成分的组合物来预防和治疗肠侵袭性大肠杆菌感染的方法。

Description

新型肠侵袭性大肠杆菌噬菌体Esc-COP-4及其用于抑制肠侵 袭性大肠杆菌增殖的用途
技术领域
本发明涉及一种从自然界分离的感染和杀死肠侵袭性大肠杆菌的噬菌体,以及一种使用包含噬菌体作为活性成分的组合物用来预防和治疗肠侵袭性大肠杆菌感染的方法。更具体地说,本发明涉及从自然界分离出来的肌尾噬菌体科噬菌体Esc-COP-4,其可以特异性地杀死肠侵袭性大肠杆菌菌株,其具有由SEQ ID NO:1的核苷酸序列表示的基因组(登记号:KCTC 12663BP)以及预防肠侵袭性大肠杆菌感染和之后使用包含所述噬菌体的组合物作为活性成分治疗的方法。
背景技术
根据其表面抗原(脂多糖,O),鞭毛蛋白抗原(鞭毛蛋白,H)和荚膜抗原(多糖,K)的组合,大肠杆菌(E.coli)被认为具有超过9000种血清型。根据发病机制、毒素和O:H血清型,大肠杆菌在病因学上分为肠毒性大肠杆菌(ETEC)、肠侵袭性大肠杆菌(EIEC)、肠道致病性大肠杆菌(EPEC)和肠出血性大肠杆菌(EHEC)。其中,肠侵袭性大肠杆菌(EIEC)进入大肠粘膜的上皮细胞,从而通过细胞坏死等形成溃疡,并引起具有血液和粘液痢疾的杆菌性痢疾。
肠侵袭性大肠杆菌是导致猪腹泻的重要致病菌。它可以降低感染猪的生长速度,导致死亡,因为治疗和预防这种感染的成本很高造成很大的经济损失。考虑到这种大肠杆菌对畜牧业的重大损害,迫切需要开发一种预防和治疗肠侵袭性大肠杆菌感染的方法。已经使用各种抗生素来预防或治疗这种肠侵袭性大肠杆菌感染。然而,由于耐抗生素性细菌的增加,迫切需要有效的替代方法。
最近,使用噬菌体作为治疗细菌感染的新方法引起了我们的注意。特别地,我们对噬菌体非常感兴趣的原因是因为基于噬菌体的治疗是一种自然友好的方法。噬菌体是感染细菌的极小微生物,简称为噬菌体。一旦噬菌体感染细菌,噬菌体在细菌细胞内增殖。完全增殖后,后代破坏细菌细胞壁逃离宿主,这说明噬菌体具有杀菌能力。噬菌体感染的特征是特异性高,使得特定噬菌体仅感染特异性细菌。也就是说,可以被特定噬菌体感染的细菌是有限的,这表明噬菌体只能杀死特定细菌并且不会伤害其他细菌。
噬菌体首先由英国细菌学家特沃特(Twort)在1915年发现,当时他注意到微球菌菌落被未知的某种东西融化并变得透明。1917年,法国细菌学家d'Herelle发现,痢疾病人粪便的滤液中的痢疾志贺菌(Shigella disentriae)被某物融化,并进一步研究了这种现象。结果是,他独自确定了噬菌体,并将其命名为噬菌体,其意思是病菌杀手。从那时起,已经连续鉴定了特异性地作用于志贺菌(Shigella)、伤寒沙门氏菌(Salmonella Typhi)和霍乱弧菌(Vibrio cholerae)等致病菌的噬菌体。
由于噬菌体杀死细菌的独特能力,已经研究并预期噬菌体是治疗细菌感染的更好的方法。然而,Fleming发现青霉素之后,由于抗生素的普及,只有东欧国家和前苏联的噬菌体研究在继续。2000年以后,常规抗生素的优点由于耐抗生素性细菌的增加而褪色。因此,噬菌体再次被视为可以代替常规抗生素的新的抗菌剂。
此外,最近全球政府强化对使用抗生素的监管。对噬菌体感兴趣的越来越多,工业应用也越来越多。
因此,本发明人尝试通过使用从自然界中分离的可以选择性地杀死肠侵袭性大肠杆菌的噬菌体而开发可用于预防或治疗肠侵袭性大肠杆菌感染的组合物,并进一步建立使用该组合物预防或治疗肠侵袭性大肠杆菌感染的方法。结果是,本发明人分离出适合于此目的的噬菌体,并确定了可将本发明的噬菌体与其他噬菌体区分开的基因组的核苷酸序列。然后,我们已经开发了一种包含分离的噬菌体作为活性成分的组合物,并证实该组合物可以有效地用于预防和治疗肠侵袭性大肠杆菌感染,完成本发明。
发明内容
本发明的目的是提供一种从自然界中分离的并可以特异性杀死肠侵袭性大肠杆菌的肌尾噬菌体科的噬菌体Esc-COP-4,其具有由SEQ ID NO:1的核苷酸序列表示的基因组(登记号:KCTC 12663BP)。
本发明的另一个目的是提供一种适用于预防肠侵袭性大肠杆菌感染的组合物,其包含可以感染和杀死肠侵袭性大肠杆菌的噬菌体Esc-COP-4作为活性成分,以及使用所述组合物预防肠侵袭性大肠杆菌感染的方法。
本发明的另一个目的是提供一种适用于治疗肠侵袭性大肠杆菌感染的组合物,其包含可以感染和杀死肠侵袭性大肠杆菌的噬菌体Esc-COP-4作为活性成分,以及使用所述组合物治疗肠侵袭性大肠杆菌感染的方法。
本发明的另一个目的是提供一种用于使用所述组合物预防和治疗肠侵袭性大肠杆菌感染的消毒剂。
本发明的另一个目的是提供一种用于使用所述组合物预防和治疗肠侵袭性大肠杆菌感染的饮用水添加剂。
本发明的另一个目的是提供一种通过使用所述组合物预防和治疗肠侵袭性大肠杆菌的感染而对养殖业有效的饲料添加剂。
为了实现上述目的,本发明提供了一种从自然界分离出来的并可以特异性地杀死肠侵袭性大肠杆菌的肌尾噬菌体科噬菌体Esc-COP-4,其具有由SEQ ID NO:1的核苷酸序列表示的基因组(登记号:KCTC 12663BP),以及使用包含噬菌体作为活性成分的组合物来预防和治疗肠侵袭性大肠杆菌感染的方法。噬菌体Esc-COP-4由本发明人分离,然后于2014年8月21日保藏于韩国生物科学和生物工艺学研究院韩国典型培养物保藏中心(登记号:KCTC12663BP)。
本发明还提供一种适用于预防或治疗肠侵袭性大肠杆菌感染的消毒剂、饮用水添加剂和饲料添加剂,其包含噬菌体Esc-COP-4作为活性成分。
由于本发明的组合物中包含的噬菌体Esc-COP-4有效地杀死肠侵袭性大肠杆菌,因此被认为对预防或治疗由肠侵袭性大肠杆菌引起的大肠杆菌腹泻(感染)是有效的。因此,本发明的组合物可用于预防和治疗由肠侵袭性大肠杆菌引起的大肠杆菌腹泻。在本说明书中,大肠杆菌腹泻包括伴随发烧,腹泻等的大肠杆菌感染引起的症状。
在本说明书中,术语“治疗(treatment)”或“治疗(treat)”表示(i)抑制由肠侵袭性大肠杆菌引起的腹泻;和(ii)缓解由肠侵袭性大肠杆菌引起的腹泻。
在本说明书中,术语“分离(isolation)”或“分离的(isolated)”表示通过使用不同的实验技术分离噬菌体的所有操作,和确保能够区分该噬菌体与其他噬菌体的特征的操作,还包括通过生物工程技术增殖噬菌体使其有用的操作。
包含在本发明组合物中的药学上可接受的载体是通常用于制备药物制剂的药物载体,其实施例为乳糖,葡萄糖,蔗糖,山梨糖醇,甘露醇,淀粉,阿拉伯树胶,磷酸钙,藻酸盐,明胶,硅酸钙,微晶纤维素,聚乙烯吡咯烷酮,纤维素,水,糖浆,甲基纤维素,羟基苯甲酸甲酯,羟基苯甲酸丙酯,滑石,硬脂酸镁和矿物油,但并不限于此。除了上述成分之外,本发明的组合物还可以包括润滑剂、润湿剂、甜味剂、香料、乳化剂、悬浮剂和防腐剂。
在本发明的组合物中,包含噬菌体Esc-COP-4作为活性成分。此时,噬菌体Esc-COP-4为以下浓度1×101pfu/ml~1×1030pfu/ml或1×101pfu/g~1×1030pfu/g,优选1×104pfu/ml~1×1015pfu/ml或1×104pfu/g~1×1015pfu/g。
本发明的组合物可以由本领域技术人员通过使用单位剂量形式或在多剂量容器中的药学上可接受的载体和/或赋形剂通过本领域的方法来配制。制剂可以是在油或水溶性介质、提取物、粉末、颗粒、片剂或胶囊中的溶液、悬浮液或乳液的形式。此时,可以另外包含分散剂或稳定剂。
本发明的组合物可以根据使用目的制备为消毒剂、饮用水添加剂或饲料添加剂,但不限于此。
有益效果
使用包含噬菌体Esc-COP-4作为活性成分的组合物来预防和治疗肠侵袭性大肠杆菌感染的方法与基于包括常规抗生素的化学物质的常规方法相比具有对肠侵袭性大肠杆菌特异性高的优点。这意味着,本发明的组合物可以用于特异性预防或治疗肠侵袭性大肠杆菌的感染,而不会影响其他有用的寄宿细菌,因此具有较少的副作用。一般来说,当使用如抗生素的化学物质时,一般寄宿细菌也会受到损害,从而削弱动物的免疫力,具有各种副作用。同时,本发明的组合物使用从自然界中分离的噬菌体作为活性成分,因此其非常自然友好。
附图说明
参考附图可以最好地理解本发明的优选实施方式的应用,其中:
图1是示出噬菌体Esc-COP-4的形态的电子显微照片。
图2是说明噬菌体Esc-COP-4杀死肠侵袭性大肠杆菌的能力的照片。盘上的透明区域是通过溶解细菌细胞形成的斑块。
具体实施方式
本发明的实际和目前优选的实施方式如下列实施例所示。
然而,应当理解的是,本领域技术人员在考虑到本发明的基础上可以在本发明的精神和范围内进行修改和改进。
实施例1:分离能够杀死肠侵袭性大肠杆菌的噬菌体
从自然界中收集样品以筛选具有杀死肠侵袭性大肠杆菌能力的噬菌体。用于本文中噬菌体分离的肠侵袭性大肠杆菌是本发明人之前已经分离并鉴定为肠侵袭性大肠杆菌的肠侵袭性大肠杆菌。
噬菌体的分离过程在下文中详细描述。将收集的样品加入到TSB培养基(胰蛋白酶大豆液体培养基)(酪蛋白的胰消化物,17g/L;大豆的木瓜酶消化物,3g/L;葡萄糖,2.5g/L;氯化钠,5g/L;磷酸氢二钾,2.5g/L),以1/1000的比例接种肠侵袭性大肠杆菌,然后在37℃下振荡培养3-4小时。培养完成后,以8000rpm离心20分钟,回收上清液。回收的上清液以1/1000的比例接种肠侵袭性大肠杆菌,然后在37℃下振荡培养3-4小时。当样品含有噬菌体时,为了提高噬菌体的滴定度,将上述步骤重复5次。重复5次后,培养物溶液以8000rpm离心20分钟,回收上清液。回收的上清液用0.45μm过滤器过滤。将得到的滤液用于斑点测试,以检查是否包括能够杀死肠侵袭性大肠杆菌的噬菌体。
斑点测试如下进行:以1/1000的比例在TSB培养基上接种肠侵袭性大肠杆菌,37℃振荡培养过夜。将上述制备的3ml肠侵袭性大肠杆菌培养液(OD600=1.5)涂在TSA(胰蛋白酶大豆琼脂;酪蛋白的胰消化物,17g/L;大豆的木瓜酶消化物,3g/L;氯化钠5g/L;琼脂,15g/L)板上。将板放在室内干燥约30分钟。干燥后,将10μl所得滤液直接点在肠侵袭性大肠杆菌苔的表面上并干燥约30分钟。干燥后,将板在37℃培养一天,然后检查在细菌苔表面上透明区域的形成。如果在滤液滴下的地方产生透明区域,则可以判断为滤液中包含能够杀灭肠侵袭性大肠杆菌的噬菌体。通过上述步骤,可以获得含有能够杀死肠侵袭性大肠杆菌的噬菌体的滤液。
之后,从上述确认具有能够杀死肠侵袭性大肠杆菌细胞的噬菌体的滤液中分离出噬菌体。常规的斑块测试用于纯噬菌体的分离。具体来说,通过使用灭菌的尖端拾取斑块测试过程中形成的斑块,然后将其加入到肠侵袭性大肠杆菌的培养液中,然后培养4-5小时。培养完成后,以8000rpm离心20分钟,得到上清液。在回收的上清液中以1/50的比例接种肠侵袭性大肠杆菌培养物,然后培养4-5小时。为了增加噬菌体的滴定度,将上述步骤重复至少5次。然后,以8000rpm离心20分钟,得到上清液。用获得的上清液进行斑块测试。一般来说,纯噬菌体分离不是一次性完成的,因此通过使用上述形成的斑块重复上述步骤。在重复步骤至少5次后,得到含有纯噬菌体的溶液。通常重复分离纯噬菌体的步骤,直到产生的斑块在尺寸和形态上相似。通过电子显微镜观察确认最终的纯噬菌体分离。直到在电子显微镜下确认纯噬菌体分离之前,重复上述步骤。在电子显微镜下的观察用常规方法进行。简言之,将含有纯噬菌体的溶液装载在铜格栅上,随后用2%的乙酸铀酰阴性染色。干燥后,在透射电子显微镜下观察形态。本发明中分离出的噬菌体的电子显微镜照片如图1所示。从形态上观察,上述分离的噬菌体被鉴定为属于肌尾噬菌体科噬菌体。
含有上述确认的纯噬菌体的溶液进行纯化。将肠侵袭性大肠杆菌细胞的培养液以噬菌体溶液总体积的1/50的体积加入到含有纯噬菌体的溶液中,然后再培养4-5小时。培养完成后,以8000rpm离心20分钟,得到上清液。重复该过程5次,得到含有足够数目噬菌体的溶液。将最终离心得到的上清液用0.45μm过滤器过滤,然后用常规聚乙二醇(PEG)沉淀。特别地,将PEG和NaCl加入到100ml滤液中,直到达到10%PEG8000/0.5M NaCl,在4℃下静置2~3小时。然后,以8000rpm离心30分钟,得到噬菌体沉淀物。将所得噬菌体沉淀物重新悬浮于5ml缓冲液(10mM三羟甲基氨基甲烷盐酸盐,10mM MgSO4,0.1%明胶,pH 8.0)中。该溶液被称为噬菌体悬浮液或噬菌体溶液。
结果,收集上述纯化的噬菌体,将其命名为噬菌体Esc-COP-4,然后于2014年8月21日在韩国生物科学和生物工艺学研究院韩国典型培养物保藏中心保藏(登记号:KCTC12663BP)。
实施例2:噬菌体Esc-COP-4基因组的分离和序列分析
如下分离噬菌体Esc-COP-4的基因组。将基因组从实施例1获得的噬菌体悬浮液中分离。首先,为了去除悬浮液中的肠侵袭性大肠杆菌的DNA和RNA,将脱氧核糖核酸酶I和核糖核酸酶A各200U分别加入到10ml的噬菌体悬浮液中,在37℃下培养30分钟。30分钟后,为了去除脱氧核糖核酸酶I和核糖核酸酶A活性,加入500μl 0.5M乙二胺四乙酸(EDTA),培养10分钟。将悬浮液在65℃下进一步培养10分钟,然后加入100μl蛋白酶K(20mg/ml)以破坏噬菌体的外壁,然后在37℃下培养20分钟。之后,加入500μl 10%十二烷基硫酸钠(SDS)溶液,然后在65℃培养1小时。加入10ml比例为25:24:1的苯酚:氯仿:异戊醇混合物,然后充分混合。将混合物以13,000rpm离心15分钟以分离每层。得到上层液体,向上层加入体积为上层体积的1.5倍的异丙醇,然后以13,000rpm离心10分钟以沉淀噬菌体的基因组。收集沉淀后,向沉淀物中加入70%乙醇,然后以13,000rpm离心10分钟以洗涤沉淀。回收洗涤的沉淀物,真空干燥,然后溶于100μl水中。重复该步骤以获得足够量的噬菌体Esc-COP-4基因组。
通过在首尔国立大学环境管理国家仪器中心使用Illumina Mi-Seq装置进行下一代测序(NGS)分析上述获得的噬菌体Esc-COP-4基因组的核苷酸序列。结果表明,噬菌体Esc-COP-4的最终基因组的大小为168,161bp,全基因组的核苷酸序列为SEQ ID NO:1。
通过使用网站(http://www.ncbi.nlm.nih.gov/BLAST/)上的BLAST研究了上述获得的噬菌体Esc-COP-4的基因组序列与先前报道的噬菌体基因组序列的相似性。从BLAST结果确认的是噬菌体Esc-COP-4的基因组序列与志贺菌(Shigella)噬菌体pSs-1(基因库登记号:KM501444.1),大肠杆菌噬菌体RB10(基因库登记号:KM606999.1),大肠杆菌噬菌体RB9(基因库登记号:KM606998.1),大肠杆菌噬菌体RB7(基因库登记号:KM606997.1)和大肠杆菌噬菌体RB6(基因库登记号:KM606996.1)具有很高的同源性(98%,95%,95%,95%和95%)。然而,他们的基因组大小彼此不同。确切地说,噬菌体Esc-COP-4的全基因组的大小测定为168,161bp,而志贺菌噬菌体pSs-1的全基因组大小为164,999bp,大肠杆菌噬菌体RB10的全基因组大小为168,401bp,大肠杆菌噬菌体RB9的大小为168,395bp,大肠杆菌噬菌体RB7的大小为168,395bp,大肠杆菌噬菌体RB6的大小为168,394bp。此外,噬菌体Esc-COP-4基因组内的ORF(开放阅读框)的数量测定为267个ORF,而志贺菌噬菌体pSs-1中的ORF数为266个ORF,大肠杆菌噬菌体RB10的ORF数为272个ORF,大肠杆菌噬菌体RB9的ORF数为272个ORF,大肠杆菌噬菌体RB7的ORF为272个ORF,大肠杆菌噬菌体RB6的ORF为271个ORF。
基于该结果得出结论,噬菌体Esc-COP-4应该是以前未报道的新型噬菌体。
实施例3:噬菌体Esc-COP-4对肠侵袭性大肠杆菌的杀伤能力的研究
研究了分离的噬菌体Esc-COP-4对肠侵袭性大肠杆菌的杀伤能力。为此,通过与实施例1中所述相同的方式通过斑点测试观察透明区域的形成。用于该研究的肠侵袭性大肠杆菌共有10个菌株,其之前已经由本发明人分离并鉴定为肠侵袭性大肠杆菌。噬菌体Esc-COP-4显示了对本实验中使用的9个肠侵袭性大肠杆菌的杀伤能力。杀伤能力试验的代表性结果如图2所示。同时,还研究了噬菌体Esc-COP-4杀死金黄色葡萄球菌(Staphylococcusaureus),粪肠球菌(Enterococcus faecalis),屎肠球菌(Enterococcus faecium),植物乳杆菌(Lactobacillus plantarum),乳房链球菌(Streptococcus uberis)和铜绿假单胞菌(Pseudomonas aeruginosa)的活性。结果是,确定了噬菌体Esc-COP-4不具有针对这些微生物的杀伤活性。
因此,证实了噬菌体Esc-COP-4具有杀死肠侵袭性大肠杆菌细胞的特异性能力和针对肠侵袭性大肠杆菌的广谱抗菌谱,这表明本发明的噬菌体Esc-COP-4可用作用于预防和治疗肠侵袭性大肠杆菌感染的组合物的活性成分。
实施例4:噬菌体Esc-COP-4对肠侵袭性大肠杆菌感染的预防作用
将100μl噬菌体Esc-COP-4溶液以3×108pfu/ml加入到含有9ml TSB的试管中。对于含有9ml的TSB的另一个试管,仅添加相同体积的TSB。然后,将肠侵袭性大肠杆菌培养物加入到每个管中以制备OD600为0.5的细菌悬浮液。之后,将试管转移到37℃的培养箱中,然后振荡培养,期间观察肠侵袭性大肠杆菌的生长。如表1所示,在添加有噬菌体Esc-COP-4溶液的管中,肠侵袭性大肠杆菌的生长受到抑制,而在没有噬菌体Esc-COP-4溶液的管中,肠侵袭性大肠杆菌的生长没有被抑制。
表1
肠侵袭性大肠杆菌的生长抑制
上述结果表明,噬菌体Esc-COP-4不仅抑制肠侵袭性大肠杆菌的生长,而且可以杀死它们。因此,噬菌体Esc-COP-4可以用作用于防止肠侵袭性大肠杆菌感染的组合物的活性成分。
实施例5:噬菌体Esc-COP-4对肠侵袭性大肠杆菌感染的治疗作用
研究了噬菌体Esc-COP-4对受肠侵袭性大肠杆菌影响的动物的治疗作用。4只25天大断奶仔猪为一组,共2组猪在猪圈(1.1米×1.0米)中饲养14天。安装供暖系统,控制周围环境。控制猪圈的温度和湿度,每天清洁地板。在实验的第7天,使用口服注射管给所有动物口服1mL肠侵袭性大肠杆菌悬浮液。上述给药的肠侵袭性大肠杆菌悬液制备如下:将肠侵袭性大肠杆菌在TSB培养基中于37℃培养18小时,通过离心收集细菌细胞。将盐水(pH7.2)加入到细菌细胞沉淀中以使细胞悬浮液浓度为109CFU/ml。从肠侵袭性大肠杆菌激发的第二天起,实验组(噬菌体溶液处理的猪)以与上述给药相同的方式口服给药噬菌体Esc-COP-4(109PFU/头)一天两次。对照组(噬菌体溶液未处理的猪)无任何处理。给两组提供同样的饲料和饮水。在肠侵袭性大肠杆菌激发之后,每天都观察动物是否发生腹泻。通过测量腹泻指数进行观察。根据粪便一致性(FC)评分(正常:0,松散粪便:1,中度腹泻:2和严重腹泻:3),腹泻指数设定如下。结果示于表2。
表2
粪便一致性评分
从上述结果可以确认,本发明的噬菌体Esc-COP-4可以非常有效地治疗由肠侵袭性大肠杆菌引起的感染。
实施例6:饲料添加剂和饲料的制备
使用噬菌体Esc-COP-4溶液制备含有浓度为1×108pfu/g的噬菌体Esc-COP-4的饲料添加剂。其制备方法如下:向噬菌体溶液中加入麦芽糖糊精(40%,w/v),然后加入海藻糖到终浓度10%。混合均匀后,将混合物冷冻干燥。最后,将干燥的混合物研磨成细粉末。上述干燥过程可以用真空干燥、温热干燥或在室温下干燥来代替。为了制备对照饲料添加剂进行比较,制备不含噬菌体但仅含有缓冲液(10mM三羟甲基氨基甲烷盐酸盐,10mM MgSO4,0.1%明胶,pH8.0)的饲料添加剂。
将上述两种饲料添加剂分别与1000倍体积的猪饲料混合,得到两种最终的饲料。
实施例7:饮用水添加剂和消毒剂的制备
饮用水添加剂和消毒剂在使用目的上不同,但组合物相同,因此它们以相同的方式制备。使用噬菌体Esc-COP-4溶液制备含有浓度为1×108pfu/ml的噬菌体Esc-COP-4的饮用水添加剂(或消毒剂)。特别地为了制备饮用水添加剂(或消毒剂),将噬菌体Esc-COP-4溶液加入到缓冲溶液中达到1×108pfu/ml,混合均匀。为了比较,将上述缓冲溶液本身用作不含噬菌体的饮用水添加剂(或消毒剂)。
制备的两种饮用水添加剂(或消毒剂)以1:1000的比例在水中稀释,然后用作饮用水或消毒剂。
实施例8:对养猪业的影响
研究了实施例6和实施例7中制备的饲料、饮用水和消毒剂对养猪业的影响。特别地,研究重点是通过实施例5中粪便一致性评分的腹泻情况。共30只仔猪分为3组,每组由10只仔猪组成(A组:饲料试验组,B组:饮用水试验组;C组:消毒剂试验组)。实验持续2周。每组分为两小组,每小组包括5只仔猪。根据噬菌体Esc-COP-4处理与否分组(小组①:用噬菌体Esc-COP-4处理;小组-②:未用噬菌体处理)。在该实验中使用的仔猪是20天大的断奶仔猪,并且在分开的彼此间隔足够距离的房间中饲养。每个小组如表3所示被划分并命名。
表3
养猪实验的小组
按照表3所示的常规饲料供给方法提供饲料,提供实施例6中制备的饲料。根据表3中所示的常规供水方法提供饮用水,提供实施例7中制备的饮用水。消毒剂与常规消毒剂一起轮流处理一周三次。也就是说,在喷洒本发明的消毒剂的那一天,没有用常规的消毒剂进行处理。结果示于表4。
表4
养猪实验的粪便一致性评分
从上述结果可以确认,本发明制备的饲料、饮用水和消毒剂在降低动物腹泻方面是有效的。因此,可以得出结论,本发明的组合物可以有效地用于提高动物养殖的生产率。
本领域技术人员将理解的是,在前面的说明书中公开的概念和具体实施方式可以容易地被用作修改或设计用于实现本发明的相同目的的其他实施方式的基础。本领域技术人员还将理解的是,这些等同的实施方式不脱离如所附权利要求中阐述的本发明的精神和范围。
保藏单位名称:韩国生物科学和生物工艺学研究院
保藏编号:KCTC12663BP
保藏日期:20140821
序列表
<110> 尹特荣生物科技株式会社
<120> 新型肠侵袭性大肠杆菌噬菌体Esc-COP-4及其用于抑制肠侵袭性大肠杆菌增殖的用途
<130> DFP17KR3053
<160> 1
<170> PatentIn 版本 3.2
<210> 1
<211> 168161
<212> DNA
<213> 噬菌体 Esc-COP-4
<400> 1
agtatgaata taattaataa gatttttgga attcaataca ttaaagtcac atataaagta 60
acgtataaag gtccgtatac cgatgaacat gaagaaccac aagttaagtc tattatatta 120
gaaaaggacc ctaactggcc agttgaattt cgtcttcctt gctatagtca ttgggctgat 180
gttgaaatta taagtattga aaatgtctga gttagagatt agaagcaatt ttagatggcc 240
atcatgcgca ttaagtaatt tcgcccaatg gccttttgtt atggatagta tccaatttgg 300
aggtctcgaa ggattcctcc aagggtgtaa ggtgaaaaat gttgaacagc aacgtcgtat 360
atttgggtta tccgggcttg ccgcccaaca agctggacga gcttatgcta gagctcagga 420
ccgtggcacg ttgttctggc ttggagttcc gttttcaaga tactctccag cgtggaaaga 480
attatacaca aatgcatatt ttgaagcagc gttccaaaat aagggctttc gtgatgcatt 540
acaagcctcg aaaggaaaag ttttgaagca cagcatggct agtggtctaa caaaagatga 600
tacaatacta accgaagctg aatttattga tgtgttaaac ctattaagag actctctatg 660
aagcctacta ttttaactga tattgatgga gtatgtttaa gctggcaatc aggacttcct 720
tattttgctc agaaatataa tcttccgtta gaacatattt taaaaatgat ccaagatgag 780
aaatttattt ctccaggtaa actctttaat tgtgatgaag aacttggtgt caagttaatt 840
gaaaaataca atcgttcaga ttttattcgt tacttgtctc catataaaga tgcattgtgc 900
gtaattaaca aactaaaaga agattataat tttgtggctg ttacggcatt gggtgattct 960
attgacgctc tgctgaatcg tcaatttaat ttgaatgctc tttttcctgg tgccttctca 1020
gaagtaatga tgtgtggtca tgattcttca aaagaagagt tattcaaaaa ggcaaaagag 1080
aaatataacg taatttgtta tattgacgat ctcgctcacc attgcgatca tgcgagtgaa 1140
atattaaatg ttccggttta ttggatggct cgaggagagc gtgacaatat tccaaaaact 1200
gctcagcgag tttatacatg gaatgatgta gaaaataagc ttttttcgcc gaaggaaaat 1260
aaagaaagtt ttgatagtga aaaagctata aaagatttaa ttgagaagat ggttaaaaac 1320
gattcttttc cttggaacac tacctggaga acgcctggat ttaatcctta taatcatcta 1380
tatcatccat atcatccata tcagacacat ccatttcaga catggaacta tattaaacct 1440
ggtggcatag agtatttgta taatagacct acttgtggtg ataatatttt ccaaggagca 1500
ttctaatgtt tgtcgttcac actatttatg aaaatgaagg taatattaca cgtgattatg 1560
gtcacgtaaa tcaatttttt agatgcaatc cagaattccg tgctcaaaaa gacgaacgaa 1620
tttttaaaaa atgtgtagaa caaggtttca tttacgtcaa gcactggatg caaggaaata 1680
aagttagaac tacatatcat aagtctttgc ctgagcttaa tgatgaattg atttataata 1740
gagatgtaaa tcaaactctg aaggatgaac aatgattctt aaaattctga atgaaatagc 1800
atctattgga tcaactaagc agaagcaagc aattcttgaa aagaataaag ataacgaatt 1860
gcttaaacga gtatatcgtc tgacttattc tcgtgggtta cagtattata tcaagaaatg 1920
gcctaagcct ggtattgcta cccagagttt tggaatgctg actattaccg atatgcttga 1980
cttcattgaa ttcacgttag ctactcggaa attaactggc aatgcagcaa ttgaggaatt 2040
aactggatat atcaccgatg gtaaaaagga tgatgttgaa gttttgcgtc gagttatgat 2100
gcgagacctt gaatgcggtg cttcagtatc tattgcaaac aaagtttggc cgggtttaat 2160
tcctgaacaa cctcaaatgc tggcaagttc ttatgatgaa aaaggcatta gtaagaatat 2220
caaatttcca gcctttgcac agttaaaagc agatggagct cggtgttttg ctgaagtccg 2280
aggtgatgaa ttagatgatg ttcgtctttt atcacgagct ggtaatgaat atctaggatt 2340
agatcttctt aaggaagaat taatcaaaat gactgctgaa gcccgccaga ttcatccaga 2400
aggcgtgtta atcgatggcg aattggtata ccatgagcaa gttgaaaaag agccagaagg 2460
cctagatttt ctttttgatg ctcctgaaat cagtaaagct aaagagtttg ccgaagtagc 2520
tgaatctcgt actacttcta atggaatcgc caataaatcc ttaaaaggaa ccatttctga 2580
aaaagaagct caatgtatga agtttcaggt ctgggattat gtcccgttgg tagaaatata 2640
cggtcttccg acgtttcgtt tgaagtatga tgcacgtttt tctaaactag aacaaatgac 2700
atcaggatat gataaagtaa ttttaattga aaaccaggta gtaaataacc tagatgaagc 2760
taaggtaatt tataaaaagt atattgacca aggtcttgaa ggtattattc tcaaaaatat 2820
cgatggatta tgggaaaatg ctcgttcaaa aaatctctat aaatttaaag aagtaattga 2880
tgttgattta aaaattgtag gaatttatcc tcaccgtaaa gaccctacta aagcaggtgg 2940
atttattctt gaatcagagt gtggaaaaat taaagtaaat gctggttcag gcttaaaaga 3000
taaagccggt gtaaaatcgc atgaacttga ccgtactcgc attatggaaa accaaaatta 3060
ttatattgga aaaattctag aatgcgaatg taatggttgg ttaaaatctg acggccgcac 3120
tgattacgtt aaattatttc ttccaattgc gattcgttta cgtgaagata aaactaaagc 3180
taatacattc gaggatgtat ttggtgattt tcatgaggta actggtctat gaaagcttac 3240
ttagaaacaa ttgtcgttgc tcaaaaagaa ggtggagatg tttctacttc tgtatcacaa 3300
attatgattg aatttataga tgcgtatgct tataataaat tcacagaaac atttgatgcc 3360
tatgaaaaag gtccaaagtt tgaaatatac cgtactctct taccaataga ttattaaagg 3420
ccttcgggcc tttaatttta taaatagaat aaacactaga gaggatatga tggaactcat 3480
tacagaatta tttgacgaag atactactct tccgattaca aacttaaatc caaagaagaa 3540
aataccgcaa attttttcag ttcatgttga tgacgcaatt gaacaaccag gctttcgttt 3600
atgtacctat acatctggag gtgatactaa tcgcgattta aagatgggcg ataaaatgat 3660
gcatattgtt ccttttacat taactgctaa aggttcaatt gctaaattaa aaggtctcgg 3720
tccaagccca attaattaca tcaattcagt ttttactgtt gcgatgcaga cgatgcgtca 3780
gtataaaatt gatgcctgca tgctccgtat tcttaagtct aaaactgctg gtcaagctcg 3840
tcaaattcaa cttattgctg atagacttat ccgtagtcgt tcaggtggca gatacgtcct 3900
tcttaaggaa atctgggatt acgataaaaa gtatgcatat attatggttt accgtaaaaa 3960
tgccaattta gaagacattc caggtgtacc tcctatttca actgagttat tcacaaaagt 4020
tgaatcaaag gttggtgatg tttatgtaga tgttaaaacg ggtaatgctg ttcctaaagc 4080
tgttgctgtt gctgcttcta ttgctttaga aaatgataag cgcacggatc aagctgttat 4140
tcagaaaact aaaattagtc gtcgattagc agcgcaagct caatattcta ctgttgatgc 4200
ttcacttcag ggtgatagct tcgccgctaa gaaatatcaa gagtttgaat ctaaagttcc 4260
ggtatataaa gcagaaggac caatgaactc tggcgttatt cagattggtt caaacttcgg 4320
caaaggagct atcggtggta tgagaagtgc ttctcgtttt aaatctaacg attatgaact 4380
agaaagcttc cgaaatcata ttgcattggc ccatgcacgt ttacgtgatc cgtctatcag 4440
actgcagagc gatataacac atcaaggttc tcaagaatat ttaaagaata aagaattctt 4500
tgattataaa accgataaaa ttttgagcga tctcgctgac attaatattt ctaatagctt 4560
tgatgttatt aagaaaatta tcaatgattt agttaaaggt tctaaagcta cgccagacga 4620
aaaggtagct attattcaat ttgtcatgaa tggcatttat aaattgatta atgaatctgc 4680
tgctcaggca tatgaatacg caagcaccga agtaactcca aaaggactga ctcaggctga 4740
gtctgatgta attgaagatt attgtgcaga ttcatatgtt gaaatgaact cgttcctttt 4800
aggtaaacca gattctaccc gtgaagaata catggaacga gctattaaac acatcgagac 4860
tctggattct gcattcgcca aaggatcagt tcttcctccg ggaactacgc tttatcgtgg 4920
tcaagaagtt acttttaaaa ctttacgcca taatattgaa aataaaatgt tctatttcaa 4980
gaacttcgta tccacatcgc ttaaaccaaa tatcttcggt gagcatggta aaaactatat 5040
ggctctagat gattccggcg cagtattttc tggtgaagga gaaggttctg ttgatgctga 5100
agatttaatg catatgggca gtcattctgc ttatgcgaat gaagatgctg aaactagcgt 5160
aggtatggta attaaagggg ctgagcgaat caaagttatc gttccaggtc atttatcagg 5220
atttccatca gaagctgaag ttattctacc gcgtggaatt ttgttgaaga ttaataaagt 5280
aagcacgtac atgatgaaag aaactgctta taacaagtat ctaatcgaag gcacaatcgt 5340
tcctccttct gaacaattag aagaatcggt atatgatggc gatcatctaa tggaaactgg 5400
tgaagttcgt ccaatggctg ggtttaatca attccttgta gaagaatcaa aagaagagga 5460
aaacgaagtt tctcaaatct tggcttcttt ggttaacatc aacagaatgt ctaaaaagtt 5520
caagatgtag tttacaagtc cctcgtgttg tgttatagta gtcttactga cataacatga 5580
ggaacacaaa atgaaatctt ctttacgctt tttaggtcaa gaacttgtag ttgaaggcgt 5640
tattcctgct gataacgctt ttaatgaagc agtttatgat gaatttatca aaatttttgg 5700
aacagataaa aagttcggaa tttttccttc tgaaaatttt tcaaagccag aacagactga 5760
aagcattttc caaggtgtag taacaggtaa atttgagtca gaagctccgg taaaaattga 5820
agtttatatt gaagacagtt tagttgcttc agttgctgct ttcatttcat tccgtaaata 5880
aaaatatggg gacctttcgg tccccattgt tatattgctc ctaatatttt actctgcgag 5940
ttgacaattc ccgtcatagt attaatgttt gaaatgcttc cagcagttcc ccctaatcta 6000
ctaagtcgtg aaagcgaatt agataatcca gtaacgcctc cactatttcc gagaacgctt 6060
tgaataccgt ttatagcagc agattcaagc cattcaaggg cagcttgtct atcaactgct 6120
ccagcctgca tgactctata cgcaaaagta acatcaaacg tagttatttg gttatctcca 6180
tcatatgata actcaggagc gctcactgac actggaatgc atccggtgaa catcactgca 6240
gtatgaggta atccattacg agcatgaaga ttaacctgaa tatctgcctc gacatcttgt 6300
ggcaaagcac gcagtccagt tactgggtct tgaacagcgt taacccagtc ttgcattgca 6360
cgatagttac aagcttctga atccattcta aatgaaataa ccaaagggtc taattctctc 6420
ccagttatac gaatattagg agagttatag ttccagtcag tttcatagga taatctattc 6480
tctggcattt ttacagaata tatcatcaac ccagatgagt tatatgccat gttaaagaag 6540
tcaattaaat atgtaccaac tgtaaatgag cccaataaac tttgaactgt acgttgactc 6600
atggcaccaa taagatattt actaacccct gattttctta tcagtttttg tgtgccagca 6660
gtaattagcg tggtaattcc ctgattaata tcgccttgag acaatcctaa ccagtctgaa 6720
tttagaccca aattattata agaaaagttg ctaattgaac ttatcaacga agagctttta 6780
gttgatggag ttgtcgcaaa aacgcagcta aacatattat tacgttggaa atctgcgttt 6840
attgcttgat tattaaattc ctctaaagaa tacattaaaa agtccccgca tataaagaag 6900
cacgatttaa cgtgataatt tctctcatag taatctcaag agtaaatgta ctagggaggt 6960
ttggagcaat agctaatccg ttaaagttac cattaggtgt tttatcaaat ctgatgctct 7020
gtatttggca tgggccaaat atttccgttt ttccatcaaa cttagatgtt gcaccaaagt 7080
ttttcaccat ccaaattgtt gggtttgaaa ctactagaac gttagttaaa ctcgatgtca 7140
ttttctcaaa tagtgtttta tttttagctg cgtcttccgg agataaaggt tcaattaatg 7200
tagaacgata ccaatcatct aaatacccct ttatttcagc agcatattga gatttgcccg 7260
tttcaccata agaaaaatag ttaaaatatt gatagatatt gataatagcc atcaaatctt 7320
ctgttgaacg cggagtcaaa tcccatgtaa acactttagt tctattctca gcaccaccat 7380
acatacttct ggctgtcgta taaatctgtt cattattatc agccattata ccttgtgtta 7440
tactttccag tgccccaaat actgcagttg aagcaatatt acttaacaca ccagtagcag 7500
tacctccgcc tctgctgata agactttctt gaacatcatt aaatctatgt gatgatgtat 7560
caacgtcaga tttagatctc ggtaaaagaa tgtttgcgac aggagcttta cttattgttc 7620
ctgaattatt gtttgatatt aatccatttg atagttttga tactgtacta ctaatagtgt 7680
ttctagctgt acttaaaata ctcgaagatg aagaagagta gttagatctc atcgatctaa 7740
gacttccaga atccctagat gacatattgt atgcagtaaa taataatcca ttcttatata 7800
ggtctgttac ctggaagtcc cctgtagtgt cattaccact agcacgccca gttggaaact 7860
gggcagtgta tgttttagtt gctacttctg atttagtact ctgtccggct gaaattttct 7920
caccggactt tttaattaaa tcagcagtta tttctttaac aattgccata ttattcctta 7980
attaactcca gtcgcatcaa atacaccagg agcagtcgtg ctcgttacgg gtgtcatatt 8040
atgaacgaca gtatttttct taataacatt attagtatta ttgattgaag gagatgcttg 8100
ttgaacagga gcttgctgtg ctttgttctt ttctattacc tggacttgtt ttgcttctgg 8160
cgatttagca gaagtttgag gtttggcatt aggctgattt ttcttgagct cttgataagt 8220
agcatcaatt ttagaaaatc tagcagcaag ttctttttta actgccggtg aattatttaa 8280
atccgggtca tccatccgtt ttttaaggtc ttcataggca gcttcaactg atttaaccgt 8340
tgagtcttta ctcatatcag ctgaattagc gtattcatca aaacgattca tagcagcacg 8400
agcttcatta gctttcatta aagcaatttt agcttcctcc ggagaaagtt gctttaattt 8460
ttcttcttcc tctgctctct cttcatcagt cgttagtgct tctttattat caacaccacg 8520
aatccagtta gatgcacgag ttttccagtt cgcaattttg tctagccctt ttgctattgg 8580
accaagatcg ccattcattc ttttatattg ataatttgca actttttctt ggtcttcttt 8640
gctaagagaa gcatttgtag tattttggaa attttctagt gctcttcctt ctacttcgtc 8700
agcagtgtct ttcatgccag gaataactcg aagaattgcc gcagataatt tagccattcc 8760
aagttgaata agctctccta aattaaaaag aacctttcca agcccttcta caatagctgc 8820
tgtcaatccg ccccaatctc cggcttccca cagcttctta attttatcaa tagaactaaa 8880
gatgctctgt aataaaggac cccatgttcc ggtttcgcta gagaatttag taaagtttga 8940
actaaacaaa tcccaagcct gcgaaaattt atctgaccaa tatttaaagt gaaccatcag 9000
cagatctatt ccaacaacaa cagccaatat cattgcagtc attttagcgg cttcaatagc 9060
agcactgacg gtatacttaa atagcatgct tgatatttta tcagtaattg aaatagattt 9120
cttaaatccg aaatcaacag tctttgttaa tttatctaaa gcttgagata attttaagtt 9180
aaatgcgtct tttttctgtt tttcttctgg cgattcttgt ttgggttcaa ctggctgagg 9240
ggtagggaaa aaatcagcat caggatcatt attaaccgct tcaggagctg gtaataaagg 9300
accaacagat tcagctgtat catcctcaac gactttaaca ggaatagcgc tttcaaccgt 9360
ggctaaacta gttcctgttt gttgaattcc ggctgtctga attttttgct ctagtaaact 9420
cgttaattta tctaatttac ttccgagcga ttcgccaatt tctttattaa tattgttgcc 9480
aatttcgaca gtttcagcaa ttaactcaga accagcagta gtatcactca ctgcgctttc 9540
tacattgtca attgctccaa ttatttcatt cgatttttct tcaacggttt gagctattaa 9600
ttcagaagca gcttgagcat catccaattt tgtagaaatg tcattaagcc cagataaagt 9660
gttagaagcg gatttagccg cttcctgaac tggtttatta tctgaaataa cttttctacg 9720
catcgtttgc atttcttgtg gctttttcat tcaaataatc caataatatt gccaattcca 9780
gttattggac cattagggcc aggaattgct aaagttgtaa aaatatcatt tgcccatttt 9840
aaaacgaatg ctggcatctc aagaaaatta atttctttaa cttcatcatt gaccttaagc 9900
aagcatttag ataacatatc gctcaccgtt aaaaattgtt caaattttcc aggaggtcta 9960
aaataaaatg tatttccttg gtattgaaat tctaatcttt ggcacacata aacatcatta 10020
atgtcataag tataaccatc tatttcttta cgagatttaa tctttccatt aaattccaat 10080
aaatgaatag aaacgaaatc aacttctgct ggtgataaat tcggacaaat agaatcaata 10140
agaagtttta aattttcatc aggaccttta acatctttta aaatgttata atgtttaaga 10200
cccattttag gaatagaaac ttctttattg cttattggaa gaactacttt cttcagtggt 10260
agtatcagat ttaaattcat ttttaacctt aactgggtct attgtttcca gtttcgttgc 10320
attagtgaac atatatagat gagttactga attattattg gataattcat ggataacttc 10380
atcaacgtaa aattctgttt taaattggtt tttactatca ttaaaaataa ttttaacgcc 10440
aggagtcaag ttaaaattac cgacagtaga acatttagca tagccatcgt attgtgccat 10500
agtttgaaga cgaatagctt cttcatatcc attcctataa gtcatttcag aataagcacc 10560
tgaccttgat actacaatag agttttcgcc ctttcctgta gtaatcattg gcaatgaaga 10620
atctaaaaat gaatgagcat agatagtagc atttttcatt gggtcgcgtt tatgaggatt 10680
cgatttagtc aaccaaacga aatcatatgc taatggatat tttaattctt ggatgaattg 10740
acctattaaa gatggctcac cgacaatcat tggatacggt tcttgattta tcatcatatc 10800
atagtccatc atgttaactc ccatgatgtc ttgccacaca aatacaaatt tgtcacttcc 10860
tacagctaga gcaacttccc tgacatacga caaatagttt tcaaatgtgc tagtccatgg 10920
aatatcagga acataagcat ttatagcatt tattgctgga gttaataacg tgcgatcctg 10980
ataaatgacg ccaagcattt cctttataga ttcacctgca tcagagaaaa acggtctgcc 11040
aaatttaaga ttttctatgg aatgaatagt tcccaattca atagcaatga tgttatcacc 11100
ttttgaatct acagatacag aaaaatgctt acatccataa attcgtgttt taacattatt 11160
aatatcgttt gcattagcta cagaaatctg aattatttca tttccatcca tttttgtatg 11220
gatattttta gaatcataaa actgcagcat tccttcattt cggccataaa gagaatcccg 11280
catagttaat gtggtaatag tagcagctaa ttcaacaaat ctattattac tccaagcgtc 11340
gtagctatca aataatttaa cgctgagatt tggatatcct gggcgttgca acatactcat 11400
tattgtttat ccttctcaat cagttttaat acgaatccgc gctcagcagg aatcattttc 11460
attattgaat ttaagctata attacttttt acgagcgtgt gattgatttg ataaaaagta 11520
aatatttcat ctgggttaac taatagctta aacacatcta ctatatcagt gtattttttt 11580
acatacttat tacaacatga catatgcaat gttaaattaa taggattcat tgcatcgaga 11640
attttttcta atgtttctat ctcgatggca tcaacaagtt ctatttgact cgattcgctg 11700
atttccttcc aatcatacca catttcatct acttgaacag aatgaatatt ttcagtaatc 11760
atctttgctt tattttcata aaactcagaa ggaaacttta atttaatttt aacattagct 11820
acatcaaaaa caggttcctt taattctttt tgatatattt caaatggaac tgtcttttct 11880
tttttacatt ttggacatac aaatgtgacc ggtactttag ttttacctat tgaccctaca 11940
aatacctgca aaaatataaa tggttgccaa gtcttcggat agtctccaaa ataatcagca 12000
attaaatcag caattatttc tttttgttct tgtggtgacc gatgttctat atcgtttcga 12060
actaacaaaa aatctcgata atcttctacc gtaaatggtt taaaacgatg aacaccatct 12120
ggtaatttac aacgaataat gtttgccata gatgctcctt ttattctatt tataaatatg 12180
ataaataaag gagctaaata tgtatgaata caaatttgat gcgagagttg gttctaaaat 12240
aatcaactgt cgcgcattta ctcttaaaga atatctagaa cttattactg ctaaaaagaa 12300
cggttcagta gaagagatcg ttaaaaagct aatcaaagaa tgcacaaatg caaaagattt 12360
aaaccgccaa gaatcagaac tactgctgat tcatttatgg gcacattctc ttggagaagt 12420
taatcacgaa aactcctgga agtgcacctg tggaactgaa ataccaaccc atataaatct 12480
attacataca caaatagatg caccagaaga cctctggtat acactgggtg acattaaaat 12540
taagttccat taccctaaaa tttttgatga taaaaatata gcccacatga tagtatcatg 12600
tatagaaacg attcatgcta acggggaaag cattccagtt gaagacttaa atgaaaaaga 12660
actggaagat ttatattcta tcatcacaga gtcagatatt gtagctataa aagatatgct 12720
tttaaagcct actgtttatt tggctgttcc aattaagtgt ccagagtgtg gaaaaactca 12780
cgctcatgta ataagaggac tcaaagaatt ctttgagcta ttgtaatggc aaatattaat 12840
aagctttatt ctgacattga cccagaaatg aaaatggatt gggacaaaga tgtttcaaga 12900
tctcttggat taaggtcaat taaaaatagc cttttaggaa ttattacaac caggaaaggg 12960
tcaaggccat ttgacccaga atttggatgt gatttatctg atcagctttt tgagaatatg 13020
actcctctta ctgctgatac tgttgagcgt aacattgaaa gcgcagtaag aaactacgag 13080
ccgcgtattg ataaattagc agttaatgta ataccggttt atgatgatta tactctgata 13140
gtagaaatac gcttttcagt catcgataac cctgatgata ttgagcagat aaaactacaa 13200
ctggcttcca gtaacagagt ataatgcttc acgtataaac gtggtataat gaatctaagt 13260
ccatccaata acaattgaat agagaacaat atgaaattag aagatcttca agaagaattg 13320
aagaaagatg tgtttataga ttcgactaaa ttacagtatg aagcagctaa taatgtgatg 13380
ttatatagta aatggctcaa taagcattca agtattaaaa aggaaatgct tagaattgaa 13440
gcacagaaaa aagttgctct taaagctaaa ttagactact actcgggacg aggagatggt 13500
gatgaattta gtatggaccg ttatgagaaa tcagaaatga agacagttct atcagctgat 13560
aaggatgttt taaaagttga tacttcattg cagtattggg gaattttatt ggatttctgt 13620
agcggagctc ttgatgctat taaatcacgc ggatttgcta ttaagcatat tcaagacatg 13680
cgagcatttg aggctggaaa ataatgagat atagcattga tgatgctttt aattatgaag 13740
aagaattcga aacggaaatt caatttttaa tgaaaaagta taatcttaag cgtcaggata 13800
ttcgtatcct ggccgaccat ccatgtggtg aagatgtact ttatgttaaa ggaaaatttg 13860
ccggatatct tgatgaatat ttttattcta aagatatggg cattgatatg catatgagag 13920
ttatataaat agatatataa tttagaggag acaatcatgt cagataagat ttgcgttgtc 13980
tgtaaaactc caatcgattc tgcattggtt gttgaaacag acaaaggtcc tgtacatcct 14040
gggccttgtt ataattacat taaagaacta ccagtttcag aaagttcgga agaacaatta 14100
aatgaaacac aacttttgct atagtgtgac ctttagtcta tagttttggc ccttcctttt 14160
tggttgggcc ttttttaatt taaaagcttt cttctacttc atcgtctgaa tcttctaatt 14220
cagctctttt tcctgccaaa gcatctctca cagagatgtc atcagtatct tttaattcag 14280
tttctttaac tcttttctta taataagctt caagttcttc tagaccttct attgtttgac 14340
aagaggcaat tttacccata aattcatcaa tagaagcttc ataaagaaat tgtttaaatt 14400
ctagtaacat ctttttctcc aaagggccga agcccttata aattaactgt ttttctaagt 14460
attcttagtt tgtacattga taatccagta gctttagaag catctttcat gcagttatac 14520
ttaacaccat ttacttctat aggtttagca gctgggttat tagctcctga attatctggc 14580
atgttatctt taattttctg aatagattta gcggaatgtt tccttccata catgccatta 14640
tttttacctg attgattgat agaatgcaat cttttagctt cttcagtcca ttttgttggg 14700
ttcattcttt tagttttact aattttactt ccccacgtaa ttggacgatt tttcatgagt 14760
tttgacatat attgtttatg ttcttccgta tggtgttttc cgtaaaatgg attaccttca 14820
cctgattgaa gttttgccat tttacgacgt tcccaggcgt aagatttatt aacgtgtctt 14880
tcatgagtat ttgaattcat tcccatacat ataacggctt taattatacc gtaatggttt 14940
ggatgaattt tagctaaaag tttatgagct ataaaatgct cttcagctgt tagttctacc 15000
aaattacact tatcatctgt accacccata catctaggaa ttatatgatg agtttcagtg 15060
tatccattaa ggcgagcccg attctgggct ctattaatta aattatcata tattaattta 15120
taattcaaag tttaacctct ttcatcacat aattaaactt ctcatcagca taacgctgaa 15180
tacgatcaag tccatgtttt aaaagatagt ttaaatgcga gtatttttta gaagatgttt 15240
ttgatttaga aactacgccc gcgtcatcta tgaggtccca gaccgttgcg attgttttag 15300
aaccatgctt acgtaatacg cgacctattg tttgtaatac aataatttta gatttaacac 15360
cgtgtgctaa aacaacgtga tgcagatttt taactgaaat accggtagaa aatacaccat 15420
aactagctac tataattatt cctttaccgt tttcagctaa ggttttcatt atattgcggg 15480
tttcggtatc aacttcccct gatacgtaat aaactttatc gtattcattt ttaattaaat 15540
cgaaaatagc tttaccgtgc gatacgtgtt taaacatgac aaaagcattt tcatcttttt 15600
gcgcaagctt aatagctaat ttagcgatcc atttatttct tttactgagc ccagtaataa 15660
tttttatttc ttcttggtaa gtttttccct ttaatttagt agtgaactca tcgggatagc 15720
gaagaaaaat actattaatt tttaactcag ttacttgtcc atcttccatt aatttagagg 15780
tcgttactgg cttaaatatt tcaccgaaca ttccaacata ctgcattata ttagctttgc 15840
catcgcgcaa tgaaccagac aaaccaaatt taaacataca gttatttaaa cctgatatga 15900
tagatgaaat actttttcct gtagcaagat ggcattcatc attcatcatc attccaaact 15960
gtgagaacca ttcttttggt tgttttacta cagtttgcca tgtaccaaca acgactggtg 16020
catcattttt atatttatca tcttttgatg ctccaccgcc aattttcttt atcattgcat 16080
gactgaataa acgatagtca acaaagtcat cagccatctg agttgtcaga gcagttgttg 16140
gaacaatgat aagaattttg ccttcataat tttccaaata ataccgagca agcaaagctt 16200
gaattaaaga tttacctgcg gatgttggaa gattaagaat tctacgacga ttaactaatc 16260
cttcgaacac tgcatctttt tgataccaat gcggttcaat tcttttattt cctgaataga 16320
tttctaattt agaaagccat tcatcaaaat cttttcttga taattcttct ttttcgttaa 16380
tctgtgggtc aatccaggct ttataaccaa agttatcaca gaacttttta atttgcccga 16440
ctaagccgaa tggaagaagg cgattataat ctaaaagacg gattcgtcca tcccagttgc 16500
catatctgaa gcgaggatta aacctatatc catcggcctc aaacgaaaag aaatctctta 16560
attcgtggaa cgtgctctct tcacaatcga tgcgtacatg actaaagtcg tgaaaatgta 16620
ctttaatatc cataattatg ccttactaaa tttgccttta gagtctcttt tcatgagacg 16680
acctttaata aatccatcgg gaataataca gtctggttgt attaatttat ttattgctcc 16740
attattgacc caaaaagttc ctgtggtagt cggtttgact ttacatcctt ttctggactt 16800
tctattaaga tgaaccatcc cttttacaaa tccttctgga acaagttctc cgggtttaat 16860
aaaaatattt ttagttccat tggtgtaaca agttgtacct aataccgtgc ccggtgagtt 16920
ttcaaatctc ttagcggaag attctttcat ctttgctata acctctgcag tcataacaat 16980
tccaccaatt ccaccaggtt tcatattata ataatttttg ctttttatta gttcaggagt 17040
tataatttct tcttcataca tgtacgcttc ttcggaagtt ttaaactctt ttagtattgt 17100
tctagagaaa ttcttttcac catatttctt tatagcctgc tgaattgcct taccggaacc 17160
aaggtagcca tcattcaagt catcagtaga gtgttttcct atatactttt taccatttat 17220
tagatttgtc gtttcatata caaagtgata catactattt tccgagtaat aaatatatct 17280
atatttatac tgaggaaata ttatgataga taaagattat attgcagagc tgaaggctct 17340
tgatgataat aaagaagcta aagctaaatt agctgaatat gctgaacagt ttggtataaa 17400
agtcaaaaag aataaatctt ttgataatat cgttaatgat attgaagaag ccctccagaa 17460
gctcgctagt gaacctatgc cagagactga tgggttatct attaaagact taattgatgc 17520
tgctgatgct gcagacggat taaaatatga cgatgaagaa gtcaatccag aggcagcact 17580
tctgattgat tctccggtta aatctgacat taaaattgaa gtagtagaaa cggataaaat 17640
tcctgaaaat accgatgttt tgattgaaga tactcctttt gttgaagaaa aattcgaaca 17700
ggctgtagct gagattattg aatctgagaa gccgtctgta tttactcttc cggaaaactt 17760
tagtccgaat cttcagctga ttggaaaaaa tccaggattc tgcactgttc cttggtggat 17820
ttaccagtgg attgctgaaa ctccggattg gaaatctcac ccaactagtt ttgagcatgc 17880
gtcagcacac caaactttat ttagcttaat ttattacatt aatcgcgacg gatcagttct 17940
aattcgtgaa acacgtaatt cttctttcgt aacattaaaa taaggataac ttatggcttt 18000
tacagttgat ataactccta aaacacctac tggagttata gatcagactc agcagtttac 18060
tgctacaccc agtggtcaaa ctggaggtgg aactattacc tatgcttgga gtgtagataa 18120
tgctccgcaa gaaggatcag cggcaacttt tgattatgta ttaaaaggac ctgccggtca 18180
aaagactatt aaagtcgttg caacaaatac agttccagaa tctgaatctg aacctgaaac 18240
agcagaagct acgacaacta tcacagttca aaataagaca cagacaacta ccttagctgt 18300
aactcctggt agccctgatg ctggagtgat tggaactcca attgaattta ctgctgcctt 18360
agcttcacag ccatcaggtg caaacgctac atatcaatgg tacgttgacg gttctcctgc 18420
gggcgaagca actggcacta cattcaatta cactcctgac gcaagcggag ttaaaacaat 18480
taagtgtgta gctcaagtaa ccgcgacaga ttatgatgca aaggaagtta cttctaatga 18540
agtgtcactg actgttaata aaaagacgca gacaactacc ttggcagtaa ctcctgatag 18600
tcctccagca ggagttattg gaacagccgt tgaatttact gctgccttag tttctcaacc 18660
cgttggagcg tctgctacat atcaatggta tgtagatgat tctcaaattg gtgaagaaac 18720
taactctaca tttaactata ctccaactac aagtggagta aaaagaatta aatgcgtagc 18780
ccaagtaaca gcaacagatt atgacgcaaa aacagttact tctaatgaag tatcattaac 18840
agttaataag aagacacaga caactacgtt agccgtaact cctgctaatc ctgccgccgg 18900
ggtaattgga accccagttc aatttactgc tgccttggct tcacagccac cgggagcgtc 18960
tgctacgtat cagtggtatg ttgacagttc tctggtcgat ggagaaacta ctactacatt 19020
taactatact cctaccacag ttggagctaa aacagttaag tgtgtagcgc aagtaactgc 19080
agaaaattac aatgaaaagg aagttacttc taatgaagta tcattaacag ttaataagaa 19140
gacaatgaat ccacaggtta cattgactcc tccttctatt aacgttcagc aagatgcttc 19200
ggctacattt actgctaatg ttactgatgc tccagaagaa gctcaaattg aatattcatg 19260
gaagaaagat tcttctccag tagaagggtc aactaatgta tacaccgttg atacatcatc 19320
tattggaagt caaactattg aagttactgc aactgttact gctactgatt atgatagcaa 19380
aactatcaca gcagaaggtc aagttcaggt aactgataaa gttgctccag aaccagaagg 19440
tgaattgcct tatgttcatc ctcttccaca tcgtacttcg gcttatatct ggtgcggttg 19500
gtgggttatg gatgaaatcc aaaaaatgac cgaagaaggt aaagattgga aaactgaaga 19560
tccagatagt aaatactacc tgcatcgtta cactcttcag aagatgatga aagactatcc 19620
agaagttgat gttcaagaat cacgtaatgg atacatcatt cataaaactg ctttagaaac 19680
tggtatcatc tatacctatc cataatcata aggggcttcg gcccctttct tcattttgaa 19740
agcacacaaa acacactcag aaaatgatgt atataatggc accaactcga taacatgaga 19800
ttgattatga gaactgaggt tgtggtgttt actcttcatg agtctggaaa gtcattcatt 19860
gaaattgctc gtgaattgaa cttacaggca aaggaagtgg ctgtattatg ggctcgagct 19920
atgactgcta agaataaatt tgaaactcga gaaaaagttg tctatagaaa aaggcatatt 19980
aataaaaagg tgaaaaatgg aacagtatga tctttatgaa aatgaatctt ttgctaatca 20040
attacgtgaa aaagcactta aaagtaaaca gtttaagtta gagtgtttta ttaaagattt 20100
ttcggaactt gctaataaag cagctgaaca aggtaaaaca tattttagtt attattgtac 20160
tgctcgcgat aaattgatta ctgaagaaat tggtgattgg ctgagaaaag aaggatttag 20220
ctttaaagtc aatagtgatc agcgtgatgg tgattggtta gaaattacat tttgaggatt 20280
aattatgttt aaaaagtata gcagtcttga aaatcattac aattctaaat tcattgaaaa 20340
actttacagt ttaggattga ctggcggcga atgggtagct cgcgaaaaga ttcatggcac 20400
aaatttctca ttgattattg agcgtgataa agtaacttgt gctaaacgaa ctggtcctat 20460
tcttcctgct gaagatttct ttgggtatga aattattttg aagaattacg ctgattccat 20520
taaagcagta caagatatta tggaaacttc agcggttgta tcttatcaag tttttggcga 20580
attcgctgga cctggcattc agaagaatgt cgattatggc gataaagatt tttatgtatt 20640
tgacattatt gttactacag aaagtggtga tgtgacttat gtcgatgatt atatgatgga 20700
atcattctgt aatacattta aatttaaaat ggctccactt ttaggtcgtg gtaaatttga 20760
agagctgatt aaattgccaa atgatttaga ttctgtcgta caggattata attttacggt 20820
agaccatgct ggattagttg atgcaaataa atgcgtttgg aatgctgaag caaaaggcga 20880
agtatttacc gctgaaggat atgtattgaa accttgttat ccttcttggc tgcctaatcg 20940
caatcgtgta gccatcaaat gcaagaactc taaatttagt gaaaagaaaa agtctgataa 21000
gcctattaaa gctaaagttg agttgtcaga agctgataat aaattgctgg gaattttagc 21060
ttgttatgtt acactgaacc gagtaaataa cgttatttct aaaattggtg aaattggtcc 21120
aaaagatttt ggaaaggtga tgggactaac tgttcaagat attttggaag aaacttctcg 21180
tgaaggtatt actctaactc aagcggataa tccttctttg attaagaagg aattagttaa 21240
aatggtacaa gatgtacttc gtccggcttg gattgaattg gtaagttaaa taaaaaggga 21300
ccgaaagggg tccctttgtt ttattcatca atgataattt ttggtagctt aacacctaat 21360
aaaacagaca aatctgaacg acccgccatt ttatccatgt ctccaccgtc aattactctt 21420
gcttcttttt catcttttgc tacagtgtaa ggatttgcag ataaagcata tctaactaat 21480
aaaccgatag atggctgcaa actttctgga tcaactacaa ctttaaatgc acctacatgt 21540
tcagggtcat ctaagtcaag gccttctgta tacggagcat agaaaattga tccaacaatt 21600
tctttttcac caatattttc tactacaccc acgattacat aatccaatgg gctgttggta 21660
tcgcaataaa gcggtaaacc attagctaag aacccgtagg cattttgtga aagatatttg 21720
tcatcttctg gtttatgttt taaccaacct gatgcagcaa gaatcgcagc ggcgcgagct 21780
gaagcaacac agaacgttgc tgtataagtt gattctttct ggatatgtga aaccatttca 21840
cacaccattc ggtataatga acgaccagct tcaggtgcag atgcataact caaatcaatg 21900
aatccagtat cagtaattcc tgtaacttta tagcgttttg atactgtaat caaagactgt 21960
agaatatctt tattgatttc atccgccatt tcggttgcaa gcaaatcttc caagaaatta 22020
ggagcatcga atccatttgc ttctaaatct tgtgctaatt caactgtgat gccagtttta 22080
agtttacgag atttaactgc ggtttgccat ttattaatct ggaatctagc atccgcaatt 22140
tcactatcag agctttcaaa tttacttgtt actgcagcat cagaaaatag acgaaccttt 22200
aaaagaacga ttgcaatctg aagagctaat tctaaatcgc tttcttcaat atcagcaaat 22260
ggtgtatctt ctaatacttt ataaacgata ttattatatt tgaataaatc gcctttattg 22320
agagttaatt tagactcttc tgttaattct gtgatttgtt ctcggtctac atacccagct 22380
tcgccggcgt aagtagcacc agttttaaat gtaaattcgt tatctgggtt aaggtatttg 22440
ataccataaa aagcagcaac aggttgatta gttctttgcg ttgctacaat gtcagaatat 22500
attaatttag tggtagcgcg agtcaaagca acgagatttg ggcgaccgat tgagttgcta 22560
ttcgttgtgg ttgattcgcg cagaagttcg ttgattttag ccattgcgct ttccttttgg 22620
tttatatgat ttatttatac cataaaaaca actaaaggga cccgaaggtc ccttaaatcg 22680
tcaaagatta gataccttta acatatacac ggcggaagta agcgttttta ccaaggctat 22740
tcagaataga aggcataccg ctctggatgc gagaagccgg agcctgagca gcggattctg 22800
caaatgggtt gataccgata ccgtaacgag ttttgaatcc cattactggt tggaagttct 22860
tcggatcgga accacgcagc ggagtcagag ctacatatgg agcgtagtaa ataccagcat 22920
ccatttcgtt cggaccttta taacctacag tgaaataatc ctgtttagca tactggtcga 22980
tatatacacg gtatttacca cccagaacac cagcaaatac tgacttggta gtatcagtgt 23040
taaagccggt agccagaccc tgtgcagcat aagaaatgcc agtatcaact gaagccagaa 23100
cgttaactac gttacgggaa gcgataatga agttaccttc accacgaccg gtctgacgag 23160
caatttcaac tgcttctttg tcaatctgga acaacagagc tttaaaggat tcacccgccc 23220
agcgagcacc acgaatatca atcggatcct ggaagtcaaa tacaccagct ttagaacccg 23280
gagtcagggt cataccagat ttaccaacct gagctgagta gttaatccaa tcaacaactt 23340
cacggttgat ttccaacatg atttcggtag ccagaatacc agacagttca gcatcagcat 23400
ccataccgtg aacagcgcgg aggtcttgtg ctaattcgat agagtaagca gctttcagct 23460
gacgagattt agcttcgata acttgtttat cgatacggaa gcccatttca ttccatgggt 23520
tatcggttga accgttgaaa ccttcctgaa gttcagcgat agaagtagcc ataccttcag 23580
cgatttctac cagtacacca gcttccattt gtttcttaat ttcagcatct aatttagcag 23640
cgtcagttgc gcttgcacta attgttactt gagcagaagc ttgcagatac acagtaccag 23700
tgtcctggaa gaagtgagta tagatatcac ctactgtggt ttgtgtgcta gcagccagag 23760
ctgtgaattt cttagcagca ccctgaccag agaacattgc atctggacca tacattgggt 23820
ggaatgcttc tttagcgcca gcagcgattg ggtctttacc atatactgca cgcagtgcga 23880
atacctggcc agtcgggctg ttcatcggct gaacaccgca aatatcgaaa gcaatcaggt 23940
taggaatagc acgacgtacc atacccataa cagctgggcc aatctgagtt actgcgccag 24000
aagtttgacc agcagcgatg ttagtagcgt tgtaaccgtg gtcaccaccg atttcagctt 24060
ctgttaagaa agaaccgaac gcctgagcga ttttttcgtc tttgtattct ggagctgtct 24120
ggaaatcttt ttcctggttt tcaaagattt tagcgataat cgcttgtttg ctattagcaa 24180
tttccggtaa accttcacct tccagtaatg gcttccattt gttcaaaagt tcagctttag 24240
ttttgatagt catttgtgtt aacctttaaa attagaaacg agatgcgact ttcgcatata 24300
cacttacaat atcttctgca ccaggtgcag ctttatcttc tacagcttca gtgacgaaat 24360
tcagtccggc tgcttcagta tcaggagtat ttataccctc agtaatagtg ctttcatctt 24420
tattagactt cttcaccatt tctacgatgg cactcaattt acttgagaat gcatctgaat 24480
aatccatacc ttcgaccaga gcagagactt tttctttttg agactcagtc agatctttag 24540
tactttcgct caatgccact tcacgctgca cataattgat atatgcgtcg cgcatattga 24600
gttcttcgaa cagacgagct gattcttctt tatgttcttg cagctcttct tccatttcag 24660
ctacaacatc aactgattct tctggaacaa cgacgttgtg ttcaacaaag agctctttta 24720
atccaccaag catggattca aacagttcgg ctttgatgcc tttatcaact gctaatttat 24780
tttcagcgag ccattctttc gcaagatggt cgatgaattt agaagcttgc tcagcgattt 24840
tcttctcagc tttttcttcg gcttcttctt tatttttttc tacttcttct tctgcttttt 24900
cagcaatttt agcgatatga gattcagcta atttaacggc gtgctgcttg acggtagctt 24960
cgaatacagt gccgaaagtt tcttttgctt ccggagaaat attaactgat tcgaaaatac 25020
tatcaagagc aacggaagca tcaatttttt gcgcttcagc aatcagttgt tctttaagca 25080
ttttgtagtc ctgttgttta gataataata tttataacgc ttttttcatg gcctctgcga 25140
gagccatata ggcgtcatcg gcacttgtat cggcttccgc cgtctgtgat tcggtaattt 25200
ccttaggagt tacccatgca tctggagcac ttggacccca tactgcatca acacctacag 25260
ttaatttgaa tccttcgttt acgatacgat aacctttatt tgtgtcagtc aatgaaccta 25320
atccacgaga agaaactcct ggaatccatc cggcacgaat attagctgct aatttatctc 25380
caggaccatg gtcaccttca ataacacgag ctcgtccgta tacgtcattt cctttccacc 25440
acatatcttc tataatgata gcggcttgca tcgggtcaac attagcgcgt ggaggatgat 25500
ttaattctcc gagagcttgt ttagttaaaa cttgctcatt gatatagtct tttaccgctt 25560
tttctaatat gcgttttgga taaagacgtt tatttctatt gacgacttcc gcttgcatga 25620
atattccttc gatgtataaa ccaggtttta aaccgaggtc ttttccatca tgagattcaa 25680
gcattggcac gccatcaata atttcgccag gttgacccca agtttcaatt agtaattggg 25740
gttcattcat tagcttaatc ctaatgcttt acggcgttta agagcttttt tacgcttacg 25800
ctgagcacga gattgacctg ctgggttggc aatcttcgtt ttggtagctt tgcgagcaat 25860
ttgtctacgt tttgctttag acagcccggt ggtttgaaat gcattacgtt cacgcgtctt 25920
gcggtcttta gtacgtgtaa tttcaccacg agcagaaaca tgtttaacga tgaattcatt 25980
tagcggcatg tcttcattaa tagaagctaa tgcaattgct aaatcagttt catcatcaag 26040
catattctcg acaattgtat ttatatcgtc tttatttaaa gcagaagaca attcgtcaaa 26100
gcgaccctgt gcttcaggaa taagtgcttc gacattctcg agaactaatt catgagtttc 26160
agggatcaga agcattattc atcatcctcg tcttcgtcat cttcgtcaga gtctttgtct 26220
tttttgtcgt ctttatcatc gctatcttca tcatcctcgt cttcgtcatc atcctcatca 26280
tcaggttctt caccttcgat taagaaattg cgagcgatag cgattttttc ttctttaatt 26340
aaatcaatcg ttcttgcagc catggcttca gcaaagaatt tacgagcggc tacgaggtcg 26400
tttgatttaa tagcttcaat taaaccttcc attaaaaatc ctcttgttct tggtcggggt 26460
cttggaaacg agcctcttta gactcttctt caatttgctt ggcttcttgt tctatttctt 26520
catcagtcat ctgcaaaata tctttcatag cagttctgtg agaaatatat ttaccaataa 26580
atggttctgc catggttagc atattaattc ttcgttccaa aatttctgct tctttgagtt 26640
cagtaaagta gctatcccga tgaaattcta tcttaatatt atttatttca tcattccact 26700
catcttctgt gattatacct ttaagcaaca gatttgtttt aagcggatct aggaaaactt 26760
cttcaaactt gtgctgtaac tcacgaataa atttagcaaa cgttaattca tcacgtgtaa 26820
tgctagttcc agaatcaaac atcacaccgc cttgttggtc ttgcgggatg cgtgaaagag 26880
gaacacgtaa tgccatataa agagcttgtc taaaccaacg aacatcttcc atattaccag 26940
tattatcggc accaggaaga gtatcaactt ctgtcacagc tttaccatcg cggcgctgta 27000
accaatagtc ttcggtcata gacatattat gctgttgatt ttttatttta ccggtcgatg 27060
cgtcatatac tacacggttt ttcatcgtgt tcatgacatg ttgcatgtgc tcggcagctt 27120
tacgagcagg catattacct gtgtctacat accaaacacg acggtcagga gcacgagtaa 27180
tacgataaat gacaacagca tcttctaata attttaattg gttagcaggt ttaacagcac 27240
gatgcaaata cccgatgata tttttaccac agcaatcgac taatccagaa tgggcataaa 27300
cgatggcagc tttaggaatt tttatttttg tgccagcttc atacattcta ccatcacatg 27360
catatgattc gtgcgcagta tcatatataa aatactcttt gtaaccttta actatttttg 27420
tgccagcttc agtttctgtt ataatttcac gaacatactg aacttgacga gggtctaatc 27480
tacgtaattc ctttatgcct tcttttggac gttttggatc aataatttta tgaaagaaaa 27540
ttcttgaatc tacataccaa cgtctaaaat gatcagaacc ttttcgttga aacgatagat 27600
gatttaacac atcgctaaat tcatctaaca tcatattttt aatttttgga ctaaatttag 27660
atttatccaa atttaacgct acgacttcag tatcatcttc atagacgata gcgtctgaaa 27720
cgatttctga aactgcatta tctacttcat agttattcat gagattacga tatgtatcaa 27780
taagctcacg agtagttttc attcctggtt catatgaacc aaaaattgtt tggaatgcag 27840
cattataagg agaagcagct tcgttcgagc ttacttcaaa ttctcttgct ccatcatcaa 27900
gctttggggc tgtaatggaa acaagatctt ctttttcttg gtctttaaaa tttcgttcgt 27960
ccattttagc ccatggagca aacaaactta atacattaaa tttcattgta ttctccaaat 28020
gggaattata gttatattta taatggactt ctctgcttta agcaggatgg ggatttctcc 28080
ccattcattt tattcccaat aatcgagagc aagagttact tcaaaagttt ggatttcatt 28140
gtttgaatcc caatctaatt gaagttcacc cacgttagta ggccacaggc ctttaatttc 28200
gacttctttt gttacggttt tagcgtcacg agcatattgg cgaacaacag cgctcttttt 28260
atattctgct ggttttccac cagtaatttc gttcccttgc ccagcagcaa tgctttgcca 28320
atcaacaaac ttctggcgag catcatgtgc ctcatcgttc attactgtaa cagtccagtc 28380
atcgaatgta cgatcgcctg ctacgttaat tttacggttc ataaatccga ctggaatttt 28440
ttctacaata ccagctggta aagcagtggc tttacattga aacgtaaaat tttgtccaag 28500
ataagaaatt tctacttgga ataagttagg tcgagcaaaa tcaccagatt caaacgctcg 28560
tgttacatca tctacaaaca tattagcctc tgtagtattt atatccctat gtttaaccta 28620
gggcatatag aattaaagaa ttaaggatat agtgtattta tatggcctgc cgaaacaggc 28680
ctttagaatc attctagtaa atcccaaaga tctacactat ttctttttga cttttctcgg 28740
ttagattccc aagtgattat ttctaaatta ttaataccgc caattatttt agcaggaatt 28800
aaattatcaa aaccgtattt gatagatacc ttgtgatcaa gttggtaagc accttctgta 28860
ccacacactc ctatcttatc agcattcggc cattttgacc aaattttctt atgcttacga 28920
gtttctttat ataccaatga aatatattca cgcatttcag atttatttgg gttccatctt 28980
ggatgattta cgccatgcat acattctact gtttttcctt tattcgcgga accatatgaa 29040
ttattgcgca ttttatcttt atgacggcaa tcacgacaaa tatcagtgtt tcttccaatg 29100
cgttggttat attcaattcc acatttatcg caacggcatt ttacatacgc ggtactacct 29160
ttaatgtctt caactttaac atcaatttca taatacataa atccatgttt aaccgctcca 29220
agaggtgtta atttataacc ctttgattga taatgtttaa aatttgacgg tacaattttc 29280
actttaacaa acttagaaat aatcacttgt ttcctcgaga ataggggccg aagccccata 29340
atcaattaac ctgcaagacc agttaactca tcgaaatctg caccagtagc agttgcgacg 29400
aaattcaaag taatataatt tatactgcgc gccggttgga tgtagaatgt tgcaacaaac 29460
tcatttctat caattactga cggagtgtta tttgttgtat cgcaaactac acgatattca 29520
taaattccac cgagagcttt aattccctgc aagtactggg aagtttctgt gcggaacgat 29580
gaacgagtaa acgcgttgtt taattcgaac aaacgatatt ttgaactacg tccgatattc 29640
gttttcaaca tattaaacag acgacgaacg ttaatacgat caaatggaga aggaacagaa 29700
gtagctgttt tatcaccata caatacgtaa ccatcaccac ctgtaccagt tactgggttg 29760
atagcttctt ggtataaacg gtcgcgctga gcttggcgag tttcaatagc aagtttaata 29820
acgttaagaa tctggccacg attataacca gctggagaca tccaagtctg agaaacgtta 29880
tcagttctcg cgcataaacc agcaatatca gctgctaatg gaacccaacg atttacatca 29940
ttatatttgt catactgata cttgtagtta ccatcaattg ctgcgtaggt tgaactgata 30000
ttaaagttat tatcagtgta tgaacctgct gcagttctcc aattgactaa gttatcaaca 30060
gcacgagtta caggaattcc aactacagtt tcacgcggtg gcgagcacag tactaagcaa 30120
tcttggcgag catccccaat tgaaacgacg tgtttttgga cagtagatgc tgtttctaaa 30180
gattcaccgg cacaagaacc cgcaataaac aactgaacat caacagattc acggtcagca 30240
aagaagtccc aagcttccat caaatctcct gctgttactt cagcatttga tgataatcca 30300
ccagacagag ttaaaattcc agagaagcct tctggccagt tttgtgcagt tgcgaaaata 30360
tattctgaac caccttttgc gaaaaagtcg tcaatataga tgttactatc gtaaatatct 30420
ttttcacctc gctttgtcga aagaacaacg ctttgaacaa tagcatcatt gcgacgaact 30480
atgatagcgt attgtgaatc agtttgtggt ccatatccaa acactgcttt ggcagtagat 30540
gcgcgtgttc cgccacctgg ataaattgga agtaatgcag aagcaccttt tgcgtagtca 30600
gctttagata cgatttcaat ttcgatttta tcgcccaact cgcccggata aagagctact 30660
actcctggaa ttccatattt ttcgagattt gcctgaaagt caacagctgt catagcagct 30720
tcggcatttt caatttcagc taataaaata ccagaatcag taataatttt tccaagagtt 30780
attactgcgg ctaaaccaga ggaagacgaa gaaatttccg cggtccagtt agaacctaat 30840
gctggatatt cgcctacttc tttcgcttta gcgataattt ttgcggtagg aatattaatt 30900
ttcttaattt ttccatcagc atctacttcg gtaactttac attctgtttc aatgtcttct 30960
gaaacatact taaccgtgat tttatctcca accgcgtagt tactacctgg ggtagaaata 31020
gtgtattcaa tattaccggc aatcggagat gagtttttag cggtatctct atcgacagca 31080
cgcacaactc gcaaatcatt tccgtattgt aagaaattca ttgcagacat aaaatagtca 31140
gcagtttcag ctgtaggttg accaaaagta ttaactaaat ctacttcatt tgtaacctgt 31200
ttaatttgaa aagcaggacc ccactggaat ttaccggcca aagctgctgt accagtagag 31260
ttattaacca cggtgctttg aaccgtagtt tctttgagct caatgcccgg agataataaa 31320
gtcattttta atcctcttta atatgcttta atatatttat accattgaca taccatgaga 31380
tactggaaca tactcagcag aatgaaccga atcaacaaat atgactggag cgtattcatc 31440
acccatatct tggagttctt ttgaaaacac ttcagatgct agtcgcatgt catctttgtc 31500
agcataatca ataaattttg attgtgttga taaccatcca aaaattacta aagacattac 31560
taaatcgtca tgataacctt cttcagccgc ccaagacacg cctttttcac taaacgttct 31620
aaactcttga atagttgcgc ggtgatgaat aataagctta tctttttcaa taaggtcttt 31680
taatgtagag catcctactg ctttcgttcg tttagtttgc ttcattccta aatcagtata 31740
tgaatcgcaa ataacgcctt cgtattctaa atccatataa agtgatttcg caactgacac 31800
accagtacta tttaattcaa tataaactgg gcattcatta tattctacta aataacgcat 31860
aacgatgtcg ggtagaatta aatgagaaat agtgtttgag tgtaaaacac caacttgttc 31920
ccacacatca tcggtaacat caataatatg taaagcgtgg taatcttgcc cacgaccttc 31980
tgagcagtct agagttgcaa tatattttct atctggttca gggcttttaa atcgatgaaa 32040
accatgatca tctggagtta cttcaatgaa atccataaca gccaatttca ttcctgaaat 32100
taatgtacca gaagtccctt caaacgccgc agtgtgttct tgacgaaatt gagctaaagt 32160
agaaccatta atggtttgta tgctccattg ccatccatcg tcaaaaatat cttcatcgtt 32220
ataaagacgt tctttaactg aattccaaat agcagtgtat ggttcaaacc ctgatttacc 32280
ttcaacagca gcagtccaaa tatcataaaa atgatttaat ccattaggag tcgtagtaat 32340
aataattttc gaacgacgac cagatgaaat tactggctga atagcaagcc aggaatcatg 32400
gaagtttgga ataaatgcgc attcgtcgat ataaatcatt gcgaacgagt taccacgaac 32460
tgcgtcagga gaggaagcat aggctccgat tgaggaacca ttatcaagtt caatagaccc 32520
tttattccat tcaacaattc ctggctgtaa aaagtcagga agcagttcaa ttgcttgctt 32580
agtacgatct aaaacttccg cagacattga gcctttgtgc gcaagaatac ctacagcttt 32640
atccttatta aagcatacaa agtgtgcaag aaaaatagct actacagttg ttttaccaag 32700
ctgacgtgat aaattacaaa cagtcatacg tttagatgac attattttga gcatatcacg 32760
ctgatagtca cgtaattgaa cctttatgac accatagtca atatgagtaa tggcgcagta 32820
tgtttctgca aaatacacaa tatcgtctcg gcattttttc cattcctcaa ccatttcacg 32880
agtccactgc gttttaatat tagctcgttt caagttagga agacccatat accgagatct 32940
tttattattc ttatctttat aagtttgaaa taattcaggc ttatcagaat tatttggaat 33000
ttttactatt ttgtgtagac gaagataatc actgaatttt tcaggatacc attttccatc 33060
ccactgtgat tttatccaat gaattccatc ttcatctttt ctttctgcta agctcgggtg 33120
ttttattaaa atttttccag cttcgtttaa cggatggaaa tcatttaatg cattaatcgg 33180
ttgttccatt tatcaccttc tcacgagctt cttgagcctc gtaagcatca ccaatttcgt 33240
ccattaattc tgttggtgaa cccatgaata ctgtcgcatt ctgaatattc atttgacctg 33300
taggaacagc gcctttggtg ccaacctgct cagatgtaat atctttcata tctttgtgaa 33360
gcttcagtat ttctctgttc gtcgtagtca tttgccccat aagagttgca aatacttcca 33420
tgtgacgagg agaatcagca ttctttgccg tctcaagaaa aatcttggct gcgtccatta 33480
gcatttgttg ttgaaaatgc atatttcgac gaactactcc ataatcatct tctaagtcag 33540
gagtacggtt ttgaggattg cttttaactt ctactaattg cagaggttca tatactttaa 33600
tttcctcccc gtcaattccg gggaggtcag aaatatctaa aagtttgttt atatcaagac 33660
cttccataat aacctctatg ttcttgggcc aggaggttct ggcggtgttg gtctatttac 33720
attgctagtg aaagtttgtt ttactgttcc atcccagtct tctgggttaa tatctcgagg 33780
aacaacttcg ctatctacag attcaaaaac accttcgcca tcaggcaaat ctcttgtatt 33840
ggcgtgaaaa tctgtataag tagtacgaat taatccttct gcatcatcta ctggaggata 33900
catccatcca tttacttcaa atgttagtga ccattcaatt ctacgacgag ataaattatc 33960
tccatctata gcttcatcta tagcagcaga catcagtaca attttaatat cccttttaaa 34020
tggaatatca tttccaaact gttcgtacat agttgtatta aaatgaggtt gaaaatatgg 34080
aagaatctgt tcaactattt gaaacatatc atcttcgtag cgagtaaaga tactcaattc 34140
ataaatcatt ttaataggag atggattata ttgtgatact acggaagttg cgcctttttg 34200
cagtaaattc tgatttaaaa tgtttgtttt aaatggagca ttatagctaa aatcaactaa 34260
atgtaaattt atacgaggta gaatagtttc aactttagct acatcttctt gcgaatttat 34320
cgatgtccat ttatttaatt tcatcatgaa gtgttccttt gatgcatacg taataggaac 34380
acgtataaac ttatcaccag attctaactg acgtttgatt tggatatttg aaaacaaatc 34440
gcccatcaag gtagcatatc gtctaaaaga cgaattataa aaataaccaa acatgatttc 34500
tcctaatctg ggctttaatt agtttataat atttattaat ccatgaaatc attatcaaat 34560
gggctagatt cgaaagattt gcctctatta ttgacaacaa cataaggttc aacatattct 34620
ttagcttcag aattaatttg atctacttca gcatactgat caatcttaat atcatgaatg 34680
ccattaagat tgcgaacagg atttaattct aattcactaa attctggaat gttaattcct 34740
tcatttttct gtagaactgg attaatttct tctccagaat aaatgaattt acctgctgta 34800
attttacgaa tagcgttttg gcctaattga taaaatggat catatggttc aacccagtta 34860
atttcgaata agctgttatc cataggaaaa tatattaaat ccccttcctt gggttctttt 34920
ccgttaactt ggtgtttaaa caaatttgga ttaatagaca aagttacttc atcctgtact 34980
tgcataccaa agttaccaaa gaatgattta gctccttcat atccttcaaa tgaatttaaa 35040
tatgcagcaa atttccaagc tttagtaaat ttatttttta ggtcttcgcc gaatatcaaa 35100
tcaggagaaa catactctct tggaacatag tagcattcta cacctcgcat ttgaatgctt 35160
tcagctacta atacatcagc taatatttgg ctgtttttat aatgattgaa atttacataa 35220
ggatttagta tttcagtttc attagtctga gaataaccag tgcgattttc taatttagca 35280
aaaagatttt tatcataagt agccatatta acctaccaaa attccaaatg gaggatcgag 35340
caagtataat tcttcgcgta atgcttcttt ttctaatcga gcttcttcta ttaagcgttg 35400
tccatcaatt gtaacaccgc ctggaagcat catgccttgg tgacgtgcta aaatttggcc 35460
atttaattct ttagctaaag ctgtagcata gtctttcacc caacgattat tataagcacc 35520
ttgcttaaca tctgggtctt gacccacaac acgacctact aaattatggt ctggattatt 35580
atatcgttca gataatgacc aactatcttg cggaccaact gttccatatc ctactgtatt 35640
tccaaccatt ttgtttgtat caatgtatga tttagtccag ctttctacga taatcaaatc 35700
atatttttgg aagtttccca tgactttgag ttgttcattt gctgaattga accaaaagtc 35760
tggaatagga gaaagcatat cttgcatcat tcccatgtaa ctggtaagct gggtaaaata 35820
ccctaaatca gctccaaagg cgtttggtcc ataaaatcta ttacaagaag tccccatgcc 35880
accattaata ccagccattc ctaaaagaaa gtcagtaaac catggatatg tagcgtttcc 35940
gtccattgac gttattgatc caacatttgt acgtaaaatt cgagttactg cgaatacgtt 36000
tgaacctctt aaatcgaaga ctccggtctt atatttttct tcgtcatctc ctacataaaa 36060
tacatgaaaa cctttgttaa gtccatcaaa atggtattca ccgtataatt ctagggcacg 36120
ctggatgcaa tcatagattt gatcgggtgt taactcaaca ttaataattg gagcccctaa 36180
acgtcttaga atgacatctt tgagttcctt tggattttga gaattatatc ctgacattta 36240
aaaatccttt ggggccttgc ggccccatgt tatgctggtg ataaaaaggt agaaagtaat 36300
acccattcgc cgtctttacg aacgtaagct tgaccatctt ttggagcttc aggaatataa 36360
cctgcttcct gtaaagtctg aacatccgcc tgtaatgaag atacattact tttaatacta 36420
cgcatttctt gattaataga agaaatgtta gtttcattag cttttattga attagttaat 36480
ccacgctctt ctaccgttga accatttgga tttgttccat ttactaattt atttaatgtt 36540
acaacctgtc ctttaattcc agtagtgtta ttaccaattt caacttgcaa gttttgaaca 36600
tcattgttaa gtctattaac agaagtttca atagttgaaa ccctatttaa aagagaccca 36660
ggaggagaag gctgacctcc actagaatca gttccaacga tttgatttag ccatgaaacg 36720
tttgctcgta gtccagatga agtgttttca ccaacaattc catttaaaaa ctcaatagat 36780
gttgtattat ctttaatttt acctttaata ctagaaggaa tatcatctga gccaattgat 36840
gtttcaatga cagttaatcg ctgtttaaca cctccgcttt tatttagctc atcagttaaa 36900
gctgaaattt ctcgtgtatt agtgttaaca tctgtgatta ttgaagtatt tcctggatat 36960
ccaatagaag ttttgataga tttaatttcg gaattaagat taatttgtga ttgatctaaa 37020
ttatgcacac gtgaatatat actttcacta aatgaaggcg gtctttgtcc taattcctgt 37080
ctaagatttc ctacttcgat tgtaagcgaa cctacatcag attcaataaa tttttcttcc 37140
aaatcactta gacgtattcc ttgggaagtt atagcatctg tattattaat gatacggtgc 37200
ttcatccccg tgctgctatt tcctacaaca ggaagaccat taatatcttg tccagcatat 37260
tgtcctagtt cccttttaat ccacagcaaa tcatttctaa tcgttctata aactgaattt 37320
gcttgcgaat taaatggacc aatatcagaa agaatattat caaccgtagt atttgtacca 37380
tttaatatat cagtatgttc acttgtgagc gtctttaaac ttgatatatc atttttatta 37440
acgctgatct gtgatagcgc ttctatatct cctgatacat ctaaaatacc ttgaatagtt 37500
ttaatatctt cctgagatgt ttcaatggca gttttaagaa ttcctacatt ttcgtcgaga 37560
acctcgacgt ttttaaacac ggaaacagtt ggtctattca ttgacccatc gtttccatac 37620
ttagtactag ctcctaatat ttcttcacca tttttaatcc atgaaatacg ttcctgacct 37680
tcgccaggaa cgctatcaac aaaaggtaac tcttttaatt caatcatttg taatccttag 37740
taatgaattt taataatata gtttaatgat atattccatg gtctagtttc ataaccaatt 37800
aatccttcac gattaagtgt accaagggca tctctcggtc cacctaattc aaatccatca 37860
ttagtgaagt atgaagcgtt atcccagtcg gcatattttc tagttccaag atatccttga 37920
taaacggacg cgccaaatgg agcttcatgt ctttggtatt ctccccagcc accagcatgt 37980
ttatggtatg acatttgttg tgcttgaaca ccgccaacat gcattccgtc acatcctacg 38040
ccaagtctat cctttccata accatcttgt cctcgttgat ttaaaatatg acctcctgtg 38100
ccagctcctc tgacgaaaag acctcgcata tcaggaatgc cagggttatt ccaatcacca 38160
ccaaatcttg ttccaactgt gtttctataa tcaggatatt gatctcctga cacggttcca 38220
ccatggcaca taatccaacc tggaggtgca gaatcacccg caaacatcat aatagttcca 38280
actggaaccc tttcagacgc atatctttca gtggcaacag gttgatcacc atttttccac 38340
ataccgccgc gcgaccaaat tccatttgct gtaagatggt ctaaatttaa agaaccatta 38400
atagtttgtc caccgcgtgt attaattaca tctgcgttcc atgctaatgc tccagagcca 38460
tcaccctcgg gggcaatacc ggcttgcgtc gttaatttta ctacaccgcg catagaacca 38520
gtagctcctc gaccatttaa tgtttcgcct gttactgcaa catctcctaa attactgtta 38580
atttccgatt gtgttcctaa acgtataaca cccttatatt cttgtgttgc aacagaattc 38640
ataaaggtat acggagaaat tgcatatcct tcgcggagag ttccttgacg agtttgcgca 38700
acagtagata attgaactac acctctcaca gattctgatg cagtatcttc ggaaggagct 38760
atttgtgaaa ttaattttat tgcaagtttt tgcgttttta atggagtcat tgccgtagta 38820
tcatcaactc cagctaaagc tgcaggtgta gatgatattt taataactcc atttgatgat 38880
tcagatgaat acctgttttg gaatacatcg tcagtatggt atttcaattt ttgtggagtt 38940
atcgacgaat tattatctga gccttctaaa gtttcttcat ttgttgaata gcgtgttaaa 39000
ccatatttag tttcagtagc atttggatac aataatcttg ttgctaatgt agccggtgta 39060
acgattttag aattattagt tccatctaaa acctcttgct ctgacgcaat cattgctatt 39120
cctttaactt ccatagttgc atcaggaata ccatttacgc cgatattact tatttttgat 39180
aatgcagact gcactgtcgt gacagtgtca ggaaaattcg atcctactgg atcgaattta 39240
acatattttg attcatttga tacgtgctga tatgtattgt tactcatgct attctctcaa 39300
aataataaaa tactgtaggt tgtgtgtgac tatctagcgt aacagtttgc gcacctaata 39360
attgccaagt tccataccca ggtttagaag gagaaattat ttcttgtttg aaagtaattc 39420
ctttatcaga gtattgttct aagatatgtt cttgattatc taaatactta acttgtattt 39480
tatttcctat ggtaggatgg tcttcaaatg aatcaattgc aataaatttt gcaaccattt 39540
cctgcagagc tgttctaacg gcactggtaa attcgattga agtcattcca ttagtagctt 39600
taacaggaat gccaaacatg ttaacaataa ccgggtcacc tggtttggct gaagtatcag 39660
taacagttcc ttcaaatgac caatagtctg tttgctgcac gccagtagga gatacgccac 39720
ttatattaac taatacagct ccaacctgtt gctctgccat atttctaaca tcattaatag 39780
cagattctac atttgggtca taaaaccctt ttgctatttg tgaaattgtt acagcaccta 39840
ctggctgatt attcataacc gaaatatcat ttttcttagt tctaaaacca agaaaatctg 39900
ctaagcggga aataactccc gctttattat taagtaaact cattatgcaa tccttatcca 39960
acggtataca gtaatagacg gttgaatatt actaatatta gcaggaggag tatgtgaaga 40020
gtttgttgtt gcgtaatctt cacgatattt tgtatatata ggaccagttt catctgggtc 40080
atattggcaa cctccaataa taaccgatcc attttcgtct tcaattaaaa ctctttcgtc 40140
ggttttagtt gcaggaagat ttgcgttttc aagcgttact gatgttgttc caaccgttcc 40200
acctgccgta tgtgaaggat ttccgctaga atctaaatca ttattgttta aagcaaagtt 40260
tggatccgta acatcatcat tccatcctac taaaacttgt cctttaccaa ataatttcca 40320
tgaaccaaat cccatataag tcaccggatt atttgggttt atagcatttt cataaattga 40380
accaacagga taaatgctgt cgaaaataga tgatattgaa ttatacgttc tagtataaga 40440
atcaactttt tcaacatttg gccaaccgat tttatcaaaa tctgttaagg ccacatcacc 40500
agtaacttca gtagatgatc ctttactaac ataacggtca tcagtcaatt caatgatgtc 40560
atctttttct aaaagagttc ctaaatcatt attgaaccat gttataacga taatgtcacc 40620
ggattcaaat tttctatcaa ataaaagact gataggtttt ccgtcttcat attctataga 40680
ataatcggtg tttgattctt tccattcgcc accaagagat atacatcctt cttgcgtatc 40740
tgaattagcg ccttcgcaca aaaacagagg atatccagct gttccagcct gctgctgtaa 40800
aattccatta aaacgaacct caagagagtt cggattaatt ggttcaccag gaattaatcc 40860
aaatgcagaa aatggaattg atttcatcgc cgataaatca gtaacataaa tgcttccttc 40920
taaagaagtc tttgatgtta gttttgaatc cagtactttt atttggcgtc ttgtatatga 40980
acttctccat tgtgatacac catccataaa tgtttcaatt tgaacagtgt caccaatatt 41040
acaaggctgt cttaatcgaa tattaaatcc atcaagagga actaattcgc cttcattttc 41100
gcccggagaa ccaaagtcac tgttttcgct aaatacatca ccgtaatata attcgttacc 41160
acgatgtttt actctgatgt tattgacatt ataactagtt ccacggaaaa tatctaaaaa 41220
gtcagtttgt ccttgaactt caactaaaaa ttctttacga gctacattac taatgtctga 41280
actgataatt ttgtcaattt gcttattttt gacatattcc cagcgtcctg gagcacaata 41340
aactaactcc aaatcactga attgaatatt aatttcaacc gatgatgacg accctttaat 41400
tgtatcgcca gaagcagcta ctagtgtaac tggattaatg ttccatgttg caaatacatc 41460
cctagctcta attactttat tataatcatt aacagttcct ttaggaagtt gtagtgttac 41520
tctcccagac gaagtattaa tagcgtatga ttttccccat tctgccgtta gtgtttgccc 41580
agatgaagcg ttataagttt tccaggcacc ggctgaatat ggaacatcac catcaccgag 41640
ttcataataa agctcatcaa agttttcatt tatttttata ccacctttac gcaggtagtc 41700
accggtacca tcatctacaa cattaccgat attaatattt tgtttcatta ttgagccacc 41760
ccgattttct gcgtagcgat aactttaact gctgctctca tgccaacaat agaagaactt 41820
acagtcgctg ttacataatt tgttttaata ctaaatgcaa tattagcgat ttcgtcttct 41880
tcggtttcat ttccaacccg catgacagca tattcagaag aaattacctc tgaattaaca 41940
gtatctacaa gaatatttat ttctgctgtt ttaatttttc ttccatctac cgattggcat 42000
gtaactagca atttagccat attgtattca gtacgatgaa atagtggaat atcaactgac 42060
ccggatgtag aaatattcca tgtaccttca gctggcgatt ccttttggcc aaacatactt 42120
tcaatagaat aattccaaac agacgtagaa ttatcagatg aaatacagcg taaagttact 42180
ttactatatg gactagttac tactaaatta cctgaaacac cttttattga atcaatcgct 42240
tgaatcgtta aaggattagt aactgatata gatccatttg agttaataaa ttcaacgcag 42300
tcaccaagtt cgcctctttc aatgataact ttaacaccta cagtagaggt atcaatatca 42360
tgcctagtac caacttttac tggagttgcg tactctgcaa tagagtgttt ttgataatat 42420
ccagtagcat gaataatttg gccatctgct ccagtgccat ttgctactgc cattttacgt 42480
tgatcgccaa acgcattata aattgcgtta aaatcactat taattttatt accaccgtcg 42540
aataagatat caccagtaga agcgttacca atttcgccgg tatcaatcaa tttctttggt 42600
tcttgaatga acatagcggt ttccttatga gtttatagta tttataaaga aaaagggagc 42660
ccatgggctc ccttaattta aaatgtaaac agaatattga tttcttctgt ttgatccatt 42720
gccatgataa taggtggcct attttccata taaatcattt cgcccgaatg cctcattaaa 42780
tcttccggat cataataatc cttttcagct ttaacgtttg ggtcatttgg atgaacttta 42840
gcttcaagag gattggtgat tattgatatt tgtctaaatc ctttatttcc tggtaatgca 42900
gcatcaggaa agtaaactga atctaaatat gctttaaaac ggatagtatt tgccttaaca 42960
cggtaaatta atccaaaatc atcttgttgc caagtgagat tatcttcata cccccatcta 43020
gccgggtctt cttttaattc ctcaggccaa ggaactacga tatattcatt cgtgcatcta 43080
tttatagata catcaggcgg aatctcaaaa agatattccc aaacataacc gtcgccgggt 43140
tcgattgttc cttcagcgtc tcctcgacct tcaggaggag tcattgacct aacagaagga 43200
gtccattttc cacctaactt aagacattca tccttattag ttaaagatgc tattgaacac 43260
gttccggtat caggaacatc taaacaacga tatactaacc agcctgcgcc tgattcagta 43320
gcattgtaag gagctgagtt acacactaca atatcgttaa ttctaaatgt gtatggatcc 43380
ggatatctag tatctcccca atctctacga ggaataactg catcaagcat agatggaaga 43440
acctttacgg ttcccatcat atgagtccac atgtcagtta cacccaatac agaatcagtt 43500
ggataaggtg gagcaaagcc cacctcattt tcatttgatg accacggttc tgatcttcca 43560
aatgtgataa agatagtgtt tttatccgga ccacttccaa ttgaattata aaaattcaac 43620
attttttctg ttctaaattt tgaagtaact atcgcacgat agataacact tgaatcattc 43680
atctatttta acctgtgttg gattttcagg gtctcttgga tttcctatat tatcttttag 43740
acgtttatta actaaatctc taaattgcgc aaacgttgtt ccagatgcgt caaatagagg 43800
actcattaat ttgcgtcgtt cagaaggcaa ttgaccttga aatattgaat tgttattttc 43860
agtattatag tcatcaggaa gaggatattc tacaccagcc attgggccag gctcataaat 43920
tgcttcgcct gttaccgaat catgctcaat ttcaccagtc ggagtcaatt tagctactct 43980
atcagcatat tcagtaggca atccagaatc ccatttgtag tttttgtatt tattaattat 44040
agtctctgta tgtttaagag ttaaaccaac attaataaac atcgttaaaa gggtaattgc 44100
tataaatcca aatcctactg gatgaacaaa acgaataacg tcagatttcc agcgggaaga 44160
aggcaaattg gatttaattt tcattacata atatgatcga cttctattaa tatagtctat 44220
attattttga agcaaatcct ttcctttaac tccacgaata atttcgcctt caaaactagg 44280
aagtctttct gctttaactt cttgaccagc aattaatctt cccaaaagat tatgaatagt 44340
tacggtccat tgcaatttac cattagaata gcttctttct atataagtaa cattacatct 44400
tcctgtagct gtataaatcg tttgtcctac taagtcttcg gtcaaagaat cagattgaac 44460
gattatatca tattcagtac cagccccaga ttcgatttca atttcaactt cttcattata 44520
aagaacttta aaaagaaatt tgtatgatgc ttcaattcct ttagtagaat aaaaatcata 44580
gctgcgtgat tcgaaaaatc ttgcgacagc atcacgtttg tcagcattta aataaatgtt 44640
tcttttatat atctctgacc acaaatattc ccatgcatgc tcttctcgtg gatatttgtt 44700
acgaattaaa tttcgtaaat tgttatactg agttccatat ccatcagaaa gatattgaat 44760
atatgcttcg caaaatgctt caaaattcga atcctgcaac aaataagaat caggcatcat 44820
tgtgccaatt aatggtctta aatcagggtc agctaatcca cgctcttctt caggcgacca 44880
aggagtttca tgttcttggt tttgtaaaaa tgcctttaaa aatactccag ttggcttcca 44940
aataatttct actgtatctc taacacgata attaaaatca tagtaagaaa ttatttcacc 45000
ggaggattta taaaaaagca tcccagatgc atatttttta aatccagtga atttaacatt 45060
tggcattact atagtgcaat cgccgtcatc ccagtattca tgaactaatc tatctggaga 45120
tgtttctgga aaattttcaa taactttagt gtattttaaa tcagcataaa ctactacaac 45180
tctatcagag ttgtttatcc aacatcgtgt gttagatttt ttagaccaat taaagaatgg 45240
ttctgcatag tatttcattg gctgaggcgt aaaagtttcc caatcagatt tttcatctgc 45300
tataaatgcc atcatatgat aatgcttatc agctaaccat tcacgaggaa attcatattt 45360
aacggcaccg attaactggt attttgatgc agtttcaggg tcattaacaa tattatcact 45420
taaaaattta aaattactcg aagatagcga aactaattta ccgtcagttg acatattcgc 45480
ataccctggt tgaatacgtc ttctttcttc ttcagtattg ccaaaaactc ttttccacgt 45540
ttttgtgtca tgatttaaaa catatattcc tttatcagca gaatcaatta tttttgatgt 45600
tctaggatta gcatttaatg tttcaacttc accaataata agagcaaaaa ctttatcacc 45660
gatagaatcc attttatagc atactgcttt aggatttcca gttatagtca tagtatcagg 45720
ttcaaaaagc ctttccgaat atgttggaga taatggatca gaatctatag gtgcattact 45780
cgtttttatg tatctaactt tgtctctggc gacaacgtaa atgtaatcat cggtgcaagt 45840
aatagcttct gcaatgcgat atacattcgc tggtaaagtc gcgtaagtgg caaaaatttc 45900
tacatcaaat cctaaatgta attgatcgcc aagtttagcg aatgttatat cctgcgaact 45960
aaatctgaca tcgtcagctg accatctgac atcagtagat ttgcggccat agaaaatctt 46020
gtcgtatcct agaacgtatg ttgtgttcgc agattggtaa tataccgtct tagataaagg 46080
atatcctaca cggtcattga agagctttac agctttccaa gtttgtcctt tatcattgga 46140
tactttaact acaggttgat agcgctcaaa aaggtataaa atcccttctg attccatcaa 46200
ataaactcgg ttaatatcct tacatacttg ctgaatagaa ccttgtattt catgatactc 46260
attttcacca ataataaaat tgcttattga tgaaacatca acatatgatg gactgaattg 46320
aaaagattca ttcatcaatg cagccattat agtgtcatta ttaaaattga cataaccaga 46380
attattaaga gtaaattttt cctgaatgaa tttattggct aattgcattt caatcatgtt 46440
ttgaaatgta taagcatttg tagcaaaagt ttcaaactct tcagtataaa tccaatcaga 46500
ctgctcaaaa tcttgtgcag ctgtagctac tctaataaca tatgatgtca atgggtcagc 46560
atcatcaaaa aagaagctgt tatttgcagt atatcctaag ttaatccatc tgtattgatt 46620
actcgggaga ttttcccccg agtttgtttt tgtctcagcg atttctacaa aatagtagaa 46680
attagcacca acgtcatccc agcgcacttg cacctgattt gcggataact tggaaattct 46740
gagactagtg actgaaggtg cttttactgt cattgtgata taggctccaa atcgatagtt 46800
aagtattgtg gacgtaagtc attttcaaat acaatcagcg aaccatcgcg agtaaagata 46860
acatcatcgg ttgggtcaga atataattca atagtctgaa cttcaaattt ttcagatgtt 46920
aaattaattt tagcgatatt ccaataaatc acatcagctg gataatttat ttcaccgata 46980
acatagtatt tgtcgcgtcc atcagaattt gctaatttgt taaaatcgtt gcctgaatat 47040
ggctgaatgt tttcattttc tgtaacatcg ccagaagcaa atggaccaat aataacttta 47100
ccaattcctt tagaatctcg gtctgttgat actatgcgaa cgtcatataa tacatcttct 47160
tctaaaccag tatcaggatt tacaaccttt cgtccagaat taaatgaaaa cgtattagat 47220
tccatagaac gatcttttat ttgattattg tatttaatac ctgcttcagg cgttttatag 47280
aagttttgta cttcacgaac aatttgaatt gtcgctgatg agccaatgat agaatgatct 47340
gcatcatcta catatgtcaa catcttagat ttagcgaaag atgagttaaa aatttctaca 47400
tcttcggtat aataacgatc aattttatca attatttgac cttcgagcca ctgttcggat 47460
tcttgcagct tatttaaagc atatgtgact tttaaattag tcttaataaa aagataatta 47520
ggagaaataa ttgacggtgt aataggagct aaattatagt ctttgagata atttttaata 47580
tcttcgcgct gtacggtagt taaatacaga cctgatttag gtttagcagc aataaatgca 47640
taaccaggtt tagtagaatc agtgaaagtc tgaactgctt gaataataga accaaatctc 47700
tctgaaacga atgtatcata gtcagtcgca gttacgcagc gttgctgggt ttcgcgttta 47760
atagtaccca attcgcgaat acgttcaata tcttctggat cgccgccgcc atctgcccca 47820
acaaaatctg ggtcatcgtt tggattttca ttaatgttga tgacagttat atttgtcaat 47880
gtatctgcgt atgaaaatcc gactgcacca ttcgcatctg caccgttagt actgatgtac 47940
tcaataacaa tcgtagagtt ctgggtaggt ttaagacctc caatataatt agcagtcaat 48000
gctccttctg ccgcattaac agaaatctcg ccttcaccaa aataaaactc agtattccca 48060
tcaatagttt cacgcatgta gtaaattgtt gatgtagaac cagcatgaac cattgacttt 48120
cttgtccagt taatccattc tgctccatca acgtatagtt taacttgatt tctatctata 48180
tttttgtcat aaatgataat aggtgttaat ttatcataga tgatttcagt tcttactata 48240
cgcccctggg ctaattttaa acgcggaaaa tattggttat ttttatcacg aatagcaata 48300
acatcttcgg tagatacaaa gttgtaagga ttaacggaag tatcctttgc atatgctaaa 48360
aagcgagtac cacgaggaat agtaatgtaa tttctattca atgcgtctgt gcaagttagc 48420
ataatttcag tttgagcagc tgattttgaa gtaggtaaat atccattatc ttgtgcagct 48480
tgaactactg aactacgcaa attagcagta cgcataaagc tttcgtacaa ggcagcatta 48540
ccaaactgct gaatgtataa tgtattataa gccaaaaggt cgcacagaac gtttaatctt 48600
gagccttcaa aatcataatc caaaaattca ttttggccat taagccattc aatgaggttt 48660
tgttttattt cagcaaatgt acccccgacg aatatctcgg gaatagcatt tgctgttctt 48720
gttaattgat aatttacagg ggtatttgcc attttaaatc ctatttaatg aatactttag 48780
atgatgcctg agccacagta tcaccgcatg atattggatc agccatttga acagctttct 48840
ttccagtgac atatacctta gaagttctag gttgtgtcac tccgccatgt gtttcatatg 48900
gctttttaat ttctgtgtgt tctgtaattg gatcacctgc tacgagaaca gcaattcctc 48960
cagtgaatac tttactttgt gtagcattca caactgttgg aggccatgct tcatggccgg 49020
cagtaacaca cttatcataa cttaatcctg acatttatgg cctctcatac acgtagcttc 49080
tcaatttatt agcccaacga ctccaatttc caactatagt ttttgtgtaa tttttaacga 49140
gagtttttct tattggagct ggaggatcag tcggttcagt agtatcagaa gatgacctag 49200
aattactgcc agaacctcca gattcacttt gttcttggta gtcatatatt aatgttactt 49260
cgtaagtgaa tgtcttctgg aggttttgag gagctttcca taaatataat tgagtattag 49320
aatcagttgg aaggtcttcc catgaagcag cagttttaaa ttcattatct aaacgatatt 49380
tcaatgcgtc atttccaaat ccaaatacag attcatacgt tccatgtaaa cgattttctt 49440
ctactaaaac cccaggagtt tcttcgtaac tagttatatt tatagatact aacgtttcac 49500
ctgtttctaa ttgagcggta aaggtgacgt cgatagaaga accttccatg gattctccta 49560
aatcagcgct cattggaagt atattagcca atgtcaatcc tcgatccatc aattgtgtat 49620
tgaccagatg aaatagaact catagatgcc attttttctg tccaatcgcc accaacgtcc 49680
caatcaactg tcccagcaac tttccaagaa agatttccat ttactgtatt agtctgattt 49740
ccttcaacta aagtggtagc atctccttta actgtaatgt cagcattacc ttcaactaca 49800
atagtaacat tacctttgac taggatagtt ccattacctt caaccgtctt agtttcatcg 49860
ccacgtacaa atattgtatt gcttccatct atttggtgga gacgattatc catgttgtaa 49920
taaatttctg atccaccgac gttagtcttt ttatcgccag ctaccaaaaa attaccatcg 49980
gcatttgtta tatcatacaa attatcaaca gtttttcttg ttcttcttcc tgacggtgat 50040
acttcctcat atgttccagt cggatgaact aatctgtatc gttcttgccc gggggtatca 50100
tcaaattcct gaatatgacc gctttcagtt tccattgtgt gaacatacgg atattcgcct 50160
ttatatgaag aaacaggttc tttgaataaa attctcgaat cattcggaat aggagggtca 50220
gctggatcag aagactttgc tacagcagca gccattgctg acaaagacct agccggtgtt 50280
ttcacttcaa taccgtatga ttccaaatta cccgtaagaa taatcatggt aacacgggat 50340
gcacggcctt ttgtttgttg ataccacaat gaatcacgac cagctttata tgccttttcc 50400
caatctccgg ctaacatagc agttaacatt gtgttaaatt tagctacacc accaacaccc 50460
atctgaaatg ccatattttc taatgccatt tgacgagaac gattaactgc ttgccaaact 50520
gggccaactt tagaatgtga tttaatgtca cgttgcatat cagccaaatc acgttcaaac 50580
aaagttaccg cttcttccat tgtaatagaa cctggatttc cggtaatttc acgaccaact 50640
tgttttgata aaactttatt aatttgagtc atatcacgaa ctggctgctt catgataaga 50700
tgaccaatac caattgtcgg atatccttca gtatcccaat aaacttttag tcttaatcct 50760
tcatcacggc gaagcatttc agccattgac atatttggat tatcatcagt tggaatttct 50820
gataatggtc tatcatcagg atttatcgca gtgtctagat tgctatcttg gataatatta 50880
gaagacgaat catatcctgc ttctccgcct tggtttaata cgttagtatc atttcctaaa 50940
cgtctaggat actgtccagt tgggtcagaa aatccttcaa gtctattagg cttttcgcga 51000
actattccac catacgtgcc aaggacaatt ccgttagttt tccatttgtc taaaaaatga 51060
ccataaactc tagttccttc taccggacca gtaacggagc ctccaattcc agacattgct 51120
gcagaagtta taggttgaat aactgacatc catggtaatt tatcagttgg aatacccatt 51180
acgtcgcctt gtgctctttg aggtggatgc agaccaacta cacgaacacg aacacgacct 51240
aattttaatg ggtccattct atcttcaaca acaccaacaa accaattaag gttattactt 51300
atcatttcca taagatttct ccattatacg tataaggtcg ttcataaatg aatttatgtc 51360
tgattttgct attattttta tttgacgaag tttttcattt tcaagaacag cagcttcata 51420
cgtatcgacc gcagcaagtg ctccttcata ttgaggatat tttctagctt tatcgccttt 51480
gtcataccaa acatatggat tatcatcgta tgatattaaa ttataaaatt tttcaccgtt 51540
ttcattcaca tgatatacta tttggtctcc acctacgttt ttgtattttt gtatagatgc 51600
ttgataagca gcttcttgcg aagtaatcca tccataatac ggatcataat tatcattaca 51660
catcaataaa acccaataca actgcggatt tccatatata gcatttgcta attcttccgg 51720
gcgtggtgaa cctttaatat aataagtacg taagcggtat cccgcaagag cacgtttgaa 51780
atagtcttta tagtttctaa aaatatctgt cataggaata gtcggcgcgt ttttattcac 51840
cgttttggcc gcatattcaa tcggatcaaa aaatgtaaag agcatgggcc ctcctgttta 51900
taaatatatt atctatttat aaggagaatc caatggcata ttctggaaaa tgggttccta 51960
aaaatatatc aaaatataga ggtgacccta aaaaaattac gtatagatca aattgggaaa 52020
aattcttttt tgaatggtta gataaaaatc cagaaattat tgcatggggt agtgaaacag 52080
cagtaattcc ttatttttgt aatgcagaag ggaaaaaacg tagatacttc atggatattt 52140
ggatgaaaga ttcttctggt caagaatttt ttattgaaat aaaacctaaa aaagaaacac 52200
aaccaccagt taaaccagca catctaacaa ctgcagcgaa gaaaagattt atgaatgaaa 52260
tttatacata ttccgttaat actgataaat ggaaagcagc gcaagcttta gctgaaaagc 52320
gcggaataaa atttagaatt ctaacagaag atggattacg agctcttggc tttaaggggg 52380
cataatggct atttttcaaa taattaatga aagcactccc caagttccaa aggttaagca 52440
atcattaaac gaaaagaaat ggattcagat aggtcttgaa tacaaaaagg ccaaagcaaa 52500
aggaatgaca ggaaagcaat ttgctgaaga aagaggaatc aaatactcta cgtttacttc 52560
agcaatgtca aaatatgctt caggaattaa aacagctgaa aagattcaaa agcttgaatc 52620
aaaaccaatg aataaactca ataagcaaga aagacaactg cttatgataa attcattcag 52680
gcaaacattg cgtgataaaa ttcgtaatga aggtgcagca attaataata aaaccaaaaa 52740
gtggtttgct gaaactatta aacaagtaaa aggacataaa gttgttcgcc cgcagccggg 52800
acgaatatat gcttttgctt atgatgctaa acacaaggaa actcttcctt actgggataa 52860
atttcctttg ataatttatc ttggtttagg taaacataat ttaatgtacg gattgaactt 52920
gcactatatt ccacctaaag ctcgtcagca atttctagaa gagcttttaa agcaatattc 52980
aaatacacct actattacta ataaaacgaa attaaaaatt gattggagtc aagtgaaagg 53040
atttaggggt gcagaccaaa tgattaaggc atatataccc ggtaatatta tgggtagcct 53100
tgttgaaatc gccccgaaag actgggcgaa cgttgtgtta atgccacttc agcagttcgt 53160
ttcaaaagga aaacgtttct ctgcaaacaa agtctggtca aatatctaat tctattatct 53220
tccattcttt tctattgttt gttctaattg gaattgaatg gaagggactt agacccatta 53280
taccaccaac atttataaag cattatgagg aatatatgtc gcaagcactg caacaaattt 53340
ttaaccaagc aaatacaact aactttgtag tatcaatacc gcatagtaat actacatctg 53400
cttttacttt aaatgctcag tcagttccta ttccaggaat taggatacct gttactgata 53460
ccgtgactgg gccgtttgga ctaggccgag cacaacgtcc aggagttaca tttgagtacg 53520
atccacttat cgtgagattt atagttgatg aagagcttaa gtcgtggata ggaatgtatg 53580
aatggatgct aggaactagt aactatctta caggtgaaaa tactgcccaa aaaacaggtc 53640
ctgaatacat tacgctttac attttagata atagtaaaac tgaaatcgtg atgtcaataa 53700
atttttataa gccttgggtt tctgaccttt ctgaagtaga atttagctac acggaagatt 53760
cagacccagc cttagtatgc acagcaacga ttccttatac gtattttcaa gtagaaaaag 53820
atggcaaaat tatagcagaa gtttaatgct tcagtttcat gtgttataat cttaactaaa 53880
tttgaggaga aacatatgaa actaatcttt ttaagtggtg taaagcgtag tggaaaagat 53940
actactgcag attttatcat gaataattat tctgcagtta aatatcaact tgctggtcct 54000
attaaggatg cattggctta tgcatggggt gtatttgcag caaacactga ctatccttgc 54060
ttaactcgta aagagtttga aggaattgac tatgatcgtg agactaattt aaatctgact 54120
aaatcagaag taatcacgat tatggaacaa gcattttgct atcttaatag taaaagccca 54180
attaaaggcg tatttgtttt tgatgacgca gttaatttcg tagcatttaa taagattgct 54240
gacgttataa ataatattga agatcaatgg tcagtccgtc gtctgatgca agccctaggt 54300
acggatttga ttgttaataa cttcgaccgc atgtattggg taaaattatt tgctttagat 54360
tatcttgata aatttaactc aggttatgat tattatatcg ttcctgatac tcgtcaagat 54420
catgaaatgg atgcggctag ggcgatgggt gctacagtaa ttcatgtagt tcgtcctggt 54480
caaaaatcca atgatacaca tattacagaa gctggattgc caattcgtga tggcgattta 54540
gtaattacaa acgatggttc tcttgaagaa cttttttcta aaattaaaaa tacactaaag 54600
gtactataat gtctgaacaa actattgaac aaaaactgtc tgctgaaatc gtaactctga 54660
agtctcgtat tcttgatacg caggaccaag cggctcgtct gatggaagaa tccaaaattc 54720
tgcaaggaac tttggctgaa atcgctcgtg cagtaggtat cactggcgat actatcaaag 54780
ttgaagaaat cgttgaagct gtcaagaatc ttactgctga atctactgat gaagcaaaag 54840
atgaagaata atggaattta aagacttttc aacgggtctt tatgtagcag ctaagttttc 54900
agaattaaca cttgatgcgc tggaagaact ccagcgctct ttacgtgttc ctaatccagt 54960
tcctagagaa aaaattcatt cgaccatatg ttattcaaga gtaaatgttc cgtatgttcc 55020
atcaagcgga agttttgaag tagcttcttc tggacattta gaagtatgga aaacacaaga 55080
tggatcgact cttgtacttg tgctagattc tgaatatctg cgctgtcgac acatgtatgc 55140
gcgggcacta ggtgctacac atgattttga tgattacaca ccgcatataa cattgtctta 55200
taatgttggg cccttatcat ttagcggtga tgtacaaatt ccggtcgtat tagatcgtga 55260
atacaaagag cctcttaaac tcgattgggc agatgattta aaataatttc acaaagttgt 55320
ttacatgctg atgaggtagt gatactatta tctcatcaaa attaattagg aaaataaaat 55380
gaaaactttc aaagagtttg ctacaaaaac tactattact gaatcttctc atggtatgga 55440
agtaaagctt ggaatggctt tagctgaagc tgagcgtctt ttctctcgta ttaaagaact 55500
tgctgctgca gtcgatcctt catcttttaa aggagaccaa actaaagtta aagcactttt 55560
agcattatgc tcagatgcag gagaaattgc taaaaatggt tctaagatga agaaacgatt 55620
agaagattta aaataatttc aaaaagttgt ttacacaggg ttttagtagt gatactatta 55680
ccctatcaac taccgaggag aataaaatga aacgttgtga attaattcga aatgttgcta 55740
ttgcaatttc tgcttccgct tttagttttt caatgtttgt tggatttata tgcggattat 55800
tgactacagc agaaaatgtt ttttcacttg tagtagcatt tttaattggt ttaatcgcta 55860
ttgttatgga taaaatttct aaaggtgaat aaatgaatat taacgaatat tatgtttatg 55920
ctggggatta tgcaaatcct tctcattttg aaggtaattt aatacctgat agagttttta 55980
atactccttt tgaagcgtgg agttgggttg aaagtaaaaa tggattttct tatcgttatg 56040
ttgaagtaac tgattggaaa ggaactaaat atcctaaaga gcattattat gtagacccat 56100
ctaaagtaaa ttttcttttg ttcgcaggcg ataattacta tccttgcggt ggatatgatg 56160
atttgattgc gtatgctgaa acagaagatg aattacgcca aattattgaa gacaataaat 56220
caaaacgatt tggcgatagt tttgactggt ggcaaatcgt aaatgcccat acacatacta 56280
ttgttgataa aggttaataa tgattcttta tgcgaaagta tcatccattg aaaatggata 56340
taaatatgat caagaagcag ctaaagcctt gattgatgat tatggcattt taacatgttt 56400
tgaagttgaa aaggtttaca ttgatcgttc atcttctcaa gttaaattag tgaaggaaga 56460
ccgtaaattt aatacagtaa attttgattt ctttattgaa acggaaaaag gtcctcttga 56520
atatgatatt ttcaagaatc ctttgggtct tgaatgcatc gtaaatatgt attatcataa 56580
atggtaaata tgctttaaga attatttgtt attattaact catatcgcac tgattaatac 56640
cctctatcat caagggttct tgcttgagag cctttgttaa taattgggaa tcatattatg 56700
gatactaaat tagctgaaat ttttgaagga aaacatccaa attttagtac aggaaagctg 56760
aaagataaaa taataaaaga aaatattttt ccatatgagt gcgcaatttg taaaatttca 56820
aaatggcaaa ataagcatat tgttctgcaa ttagaccata ttgatggaaa taacaaaaat 56880
catcttaaat caaatttaag attattatgt ccaaattgcc attcgcaaac tgatactttt 56940
gctggtaaaa atattaaaaa taataaaaag cgttataatg ttagtgatga agaaatttta 57000
aacgcactat taaattcggc tactatatca tctgcaatta cttcattagg tttaagtaaa 57060
ggcggaaact ataaaagatt cattaaaatt gctaatgata ataaattata tcatttactg 57120
gtaaatatta atgaaaagat tttaactgat gaaatttacg aagaattagt taaaatcgat 57180
tattctaaat ttggatgggt tagtaaagct gctaaaataa taggtataag cccacaaaaa 57240
gctagaaaat ggatagaacg aaagtgtcca gaattgatag aacaatcttt ttcacgtaat 57300
aaataatata gagcgagaat ggtcaaattg gtaaaggcac agcacttaaa atgctgcgga 57360
atgatttcct tgtgggttcg agtcccactt ctcgcaccaa atttgcggat atcgtataat 57420
ggcattacct cagacttcca atctgatgat gtgagttcga ttctcattat ccgctccaat 57480
ttaatttact ccgtgtagct cagtttggta gagcgcctga tttgggatca ggaggtccaa 57540
ggttcaaatc cttgtatgga gactggaggc gtggcagagt ggtttaatgc accggtcttg 57600
aaaaccggca gtcgctccgg cgactcatag gttcaaatcc tatcgcctcc gccagttttg 57660
ctgatttagc tcagtaggta gagcaactca cttgtaatga gaaggtcggc ggttcgattc 57720
cgtcaatcag caccaaggcc ctgtagctgg aaggttcaag caagcgactc ataatcgcca 57780
gatggtggtt caattccacc cagggccacc aaattaattt ggggagttat cccgtagagg 57840
tagcggtgtg gactataaat ccattgtcat tgcgactcgg gtggttcgac tccatcactc 57900
cccaccaatt tggatgtgta gctcaatggc agagcgatcg cctgttaagc gattggttat 57960
aggttcgaat cctatcacgt ccgccaaatc cgaggcatag ctcagaagga agagcaagga 58020
ccttctaagt cctaggtcgt aggttcgatc cctactgcct cgaccaaaca agaaaccggg 58080
tcgctaccgg taagtcgtcg gactgatgtt ccctgagtaa ggactgacat tatcaaatct 58140
ttacgatctg ttaatgtccc cttacatcac agcagaaacg gcgcacagaa ttatcgattc 58200
gaggaaatat ctttgccgta agccgagtag cgtttttgac ggaacgttcg gatatggtcg 58260
agatatggcc ttttaaaaat attgagtagc gtcaactgct taataaccgg gttcgaatcc 58320
cggcgtttcg tacaaacact tgccttagca ggtggaaccc cgacaaggtt gccgcaaggc 58380
ttagccccga ccgaaaggtt ggggcttttt agtataaata tagtagtata ttaaatccac 58440
gaattaaaac aggaaataag atgaaatcat atgctcaatt tttaaatgaa gcggtgttaa 58500
atgaagcatc tagcaccgaa attcaagctg tcgcaaaagc agccattgca gcgggtaaat 58560
attcctataa agatgcttct gacgaatcac gattccaatt tgctcgcgac atgaaagcag 58620
aaggatttac gggaaatgca gttagtatgg cctggaaaag tttagttgct actggcgctg 58680
cttttgcaaa gccttcgggt aaacctgctc ctaaagcaga tcctaaagcg gcacaagaaa 58740
aaaatatcgt taaaggaatt atctctaaat atgaagctat ccttaaagag cttttagtaa 58800
tcaaaaccga aggccaaaag ttagcccgtg cttatagttt caaagataat ccacatgttc 58860
actctcttga gtatgttgaa gacatccaaa aaattattaa agaccgcatt tggtctgcta 58920
aacaaatcaa ataacattct tagccccgac tgaaaggttg gggcttttta gtttgaatca 58980
catagagaat gctgctacgg atagtaacaa agtaataaat aattaataac caaccgataa 59040
attatttcaa ggattttaaa tgaaaaccta tgccgaattt ttaaccgaag cagcaaaatt 59100
accatctgaa gcagatctta ctaaagtatt cttccaattg gacccaaaag accgcggcga 59160
ttttcttaag tggaaagcta aagctattga aatgtacaac atcgataata gttcttttac 59220
aatgagtcaa gaaaataaat tcaataaagc atttttcaaa atttctaaga aattggcatc 59280
tggcgctcag gttcctaaat ctgtattagc tactcctgaa cgtgcacctg ttaaaatttc 59340
taagaatatg ttcgacacta aaaaatacgt taatgctttg aataaagctc ttgatgcatt 59400
ggatgatgca aagaaggcag cccgcgatct tcaagacgtg tacaccgatt ttgatcgtaa 59460
aactaaaggt tctatttcaa atagcgaacg caatagtgta agtgtttatt ctgatagcct 59520
tgatgttctt ggcgatgcgt atactgaaat taaaaatcgt attaacaccg catctaagct 59580
aaaagctgct gccgaagcta taataactaa actaggcaaa taattttaaa tccctatcta 59640
aatgataggg ctttttggta tctaggcctt tctggacctc tctaggcatc atttagttta 59700
taccctttat aatatattat cctatctttt aattgcccat ccctgcccta gaattcccta 59760
aaaattttta aaattttttc acaaaactat ttacatccct gttcttccat ggtactatac 59820
aactatcaac tactgataca gaaaaacaac ttggagaatg aaatggataa ttacggcgaa 59880
ctgttcaact tctttatgaa atgcgtttca gaagatttcg gtcgtacagt gaatgatatt 59940
aaagttatcg gtcctgacca tccgatgttt gaaacttacg cagtaatggg taatgaagac 60000
ggacagtggt atactgtaaa ggttgtgatt aacatgttca cagcagaagg ttatgttaaa 60060
ctgtcttcta aagtttacca cgataacgac gaaatcgcag aagaatattt caataatatg 60120
aaataagttt acataggctc atgattgaga tattatgagc ctacaatttg aggaaaaccg 60180
ctatgtctct ttataccgaa ctgaatgaaa cttccgaaaa atcttttgat gatatcttat 60240
caataatgca aaaacaggta ttagaacagc ttagtgaagc cgcaagcaat gggcacaagg 60300
cttgtcgagt ccaaagccca catcgccgca tgtatgaacg ccctcttatt aattggctag 60360
aaagcgaagg tcttacagtt aagatttgcc ctgctaaatt tgatgtccca cgtattctta 60420
atatttactg ggataaaccg gctgagaaat tggttgagaa aagtgaccct tgggttgtta 60480
atgtaaaaac atgtgacagt ggatgctcac ttgaggtgtc tgctgtaatt aaaggcactc 60540
atggtgaaaa atcatggggt tggcctagta aagataaaga aatcgtgtta agtgtaaaag 60600
ctactagtat tagtactcct atagctaaaa gcattatcgc cgccgccgtt gaagaagctg 60660
aacgaatttg taaaattaaa aatagtttac atctcttaaa tagtatgata taattcttcc 60720
acagatttta tttttaatca acctaaggaa atactatgaa cacactgaag aaaattgttg 60780
aatttattcg cactaaactt ggttctgcta tggctaaaaa tttatctgtt gaagaacagt 60840
atactgctgc agcagcaaaa ctacttgata aaattaaaga tctaaaaact gcttctgtta 60900
aatctattaa tgaagaaaaa cgtattcgtg aacttattgt cgaaaagaat cgacaagccg 60960
aatcaaaaga gcgtgaaatt cgtaaacttc tttccgaagg tcaagatgta acaatgcatg 61020
ctaaactcgg tttactatat cgtcgaacag ctgagcagtt gactactaag gctgacggtt 61080
atgctgaaat gcgaattgaa atcgccaaga aagtagttga gttagatgat gctcgtcaag 61140
aacttgcggt taaattggaa tatatccgtg aaactcgtgc agcaaatgcc cttggaatta 61200
gtactgccga tgatgtagtt gaaattgcag cactgactaa ggttgatatt gaagataccc 61260
ttgctcgagt tgaaaccttt aacggtaata tttctggggt tgaaactacc tctgccgatg 61320
ttcaggaata cattaattct ctgaaataat gataaggggc ttcggcccct tatacttgga 61380
gtaaatagga atgaaaatga aaatgcaaag tgatttcaat tcaatgtttg aagagttcca 61440
aagacaggtt gatgttccag accaattact aaatgctctt aaacgcatgg cagaaggacg 61500
taattattat tgggggtctt catacgaaac tgatgaaagc ctttccggaa gattttctag 61560
aggtaaaaag tctttaatac gtcctggaat actcattaac agtattgaat caattcattc 61620
attgacgtgt gattttgatg ttgaatttac tgatttcatt tctcctgaat ggacggtttg 61680
ttatttaaac gacgattatg attatcttgg cgtttatagt ttaagtgacg catggtttaa 61740
acgtaattta caaaagtcaa atttattcta tattgatact acggtaaaat ttcagggaaa 61800
gaaatatttc tttactctta tagttgattc tgaaacaaag catgaaaata aacgtattct 61860
tagtaaaaag aatatcttaa ctattgttga tgatcttttt gataaattag tggaaaatcc 61920
taattttgaa agcgatttat tattagaaaa atttgttaag gaatgtagag aatatgtcaa 61980
agccatcact ataccttcca agtaaacctg tgaagtatga accaaagcgt cagctaattt 62040
ctactgatgt gttaataggt cctgtggtag ctgtatcatt tgtgattttg ctaattgctg 62100
gaatggttat agacgttatg actgatattg aatctggtgt aatatttgga gcaacactaa 62160
ttcttccatt ggtagttccg tttttattag tacctgtaaa ttgggtagga tactggtatc 62220
aaggaagaca ctatcgtaaa cgtgtacgtg attggaaagc ccagtgcaaa aagattaaaa 62280
aagaacatca gcttaaactt gctgcgtatg aatttgatga aattatgaaa tttgttaagg 62340
aatcacgatg caaaagccaa aactaaataa agtcaaatat tctttttctg agtcattttt 62400
aatttttgct gtggcgttgg ctgcagctct tgcgggtagt cttattggat tgttaattga 62460
ctgttttatt ttaaacatcc gcagtaatgt cagcggtata gtagatataa tagaagtttg 62520
gagcgaactt cattatacta tagtaatttc attattttca ttctttggta ttattttata 62580
ttttcattat gataatttta aaataaattg gcaaagaaaa aaggattaca aaatacaatt 62640
aaaagaatat aataactaca tgtcttatat tgaaaatgaa tcaatgaaag agtttgtgag 62700
tgattgtagg aaaatcaaat gattttaaaa actcgctggt atgatttaga tgatggggac 62760
gatggcattt cagttgatag agttgactgg agcggctgtt ctgaagatac aaagaaacga 62820
ttaattaggg agtttagaat gggatatcaa gcagctaagc catctactgt aacagatgat 62880
aagttcgtat gtattcaaaa cggtcgtgct aagttaacga acgctgattg gtttacaggc 62940
aagaatatgc ttttatggta tatcattagt cttcctgtgt catcattcgt attttatttc 63000
tttggaaaaa atccaatgga tagaatagga gattgggctc tttttactct gcttgttaat 63060
atttttataa cagcagtaat atcaggaata tggtgcgtgt tcattgaaat gccatggcgg 63120
ttacgtaggc agcaaaagat ttttgatgaa aagaaatata cccaaaattt aaataacttt 63180
atcactgaat gcaggaaatt aaaatgaaaa cactatcagc tggtattatc tttatgacag 63240
aagataaaga tttatttatg ggacgagtta ctggttctcg taaacctgga atgatggcac 63300
atcgctggga tattccaaag ggccgtgtag aaagttctga tttgaatgca ctggaagctg 63360
caaaaagaga atgctcagaa gagactggtt ttatcgatta taattcagac cttctagaag 63420
acctaggtgt atttaaatat tctagtaata aagacttaca gttattttat tatacgattc 63480
cagtagagca tgagatgttt agaaattgcc attgcgagtc ttattttgaa aataaagatg 63540
gtgttatgat tccagagatg gatgcttttg cccttattcc tcgtactcag tggcaatatg 63600
tgatgggtcc ttcactttac cgaataatga acagcctctt ttaatttata aataccttct 63660
ataaatactt aggaggtatt atgaatatat ttgaaatgtt acgtatagat gaaggtctta 63720
gacttaaaat ctataaagac acagaaggtt attacactat tggcattggt catttgctta 63780
ctaaaagtcc atcactaagt gttgctaaat ctgaattaga taaagctatt gggcgtaatt 63840
gcaatggtgt aattacaaaa gatgaggctg aaaaactctt taatcaggat gttgatgctg 63900
ctgttcgcgg aattctgaga aatgctaaat taaaaccagt ttatgattct cttgatgctg 63960
ttcgccgctg tgcattgatt aacatggtct tccaaatggg ggaaaccggc gtagcaggat 64020
ttactaattc tttacgcatg ctccagcaaa aacgctggga tgaagcagca gttaacttag 64080
ctaaaagtag atggtataat caaacaccta accgtgcaaa acgagttatt gcaacgttta 64140
gaaccggaac ttgggacgcg tataaaaatc tataaagttg tttactttct cctagaattg 64200
tgatagtata ttaacagtta cttggaggga taaaatgact cgtattaatt tgactttagt 64260
atctgaactt gctgatcaac atttaatcgc agaataccgt gaactgccgc gtgtttttgg 64320
tatagttcgt aaacatgttg caaatggtaa gcgggttaaa gattttaaaa tatcttccga 64380
gtttatttta ggttctggtc atgtcacgtt cttttacgat aagttagaat ttttgcgaaa 64440
gcgtcaatca gacattataa cggaatgctt aaaacgtggg tttagtataa aagatactga 64500
agttcctgac atcagcgata ttccagcaga atggaaaaat gattataatc catgcaaatc 64560
agctattaag ttgagtcaac aacgactcga tgaaaaaatt ttaatgaagc catactggta 64620
taaatactac ggtaaaacta tttacattta aaggaaacac atgaaaacat atcaagaatt 64680
tatcactgaa gcagctatta attctcaaat tatcgctgaa tcttttactg atcttttgaa 64740
atttaaaaaa ggtcaaaaaa tcactgctgt attggatgat ggtacagaag ttgagatgga 64800
tgtacaggga tataattatg cagtagatgg aaaactgtat aataaatctc atgctaaatt 64860
tgattcattt gacgattttg ttaatacagt tgaagatgaa aaaactcgta gatccattgc 64920
aactggcgac gctaaggttc ttatggcaca cggtcatgaa cgtatccgcg ctaagcagaa 64980
taaaatgggt gaagataatt ttgcattagt tggttatcaa tctggtaaac aaacttatgg 65040
ttatcagcgt actgctacca tgtataacaa aaatggtaaa atcgctttcg tgaatagcaa 65100
aggctctatt cagtacgtca aatcattcaa ataagcaaat aagaaatatg ggaacaagct 65160
ggacctcatg attctatgag ggattcccgc caacctgtaa taaggtcgag cccaagtgcg 65220
gtaatgggta aatacagaaa tggacaattc atgcgccatg gaatggccca aatttagaga 65280
gaataaaatg agaacatttt taactggtcc ttatctatcc ctgatgaatg cttttacaca 65340
ccattctgat gctagagtag aagaaatttg taaaaacgat tatattccac catttgaaga 65400
cttgcttaaa caatattgta cacttcgact agatggtgga cgccaatctg gtaaatcaac 65460
tgctgtgact aactttgctg ctaattggct gtatgacggt ggaacagtta ttgttctttc 65520
taatacttca gcttacgcta aaatttctgc aggccacatt aaaaaagaat tttctcgtta 65580
ttctagtgat gatatacgtt ttcgtttatt tactgattct gtccgtagtt ttatcggtaa 65640
tagaggcagc aagttcagag gtttatcgct ttcgcggatt ttgtatataa tcgatgagcc 65700
tgttaaatct cccgatatgg ataaaattta cgatattcat attgaaactg tacaatactg 65760
ttgcaatagt aaatgttgca ccggtggtat tactcgtcct caattttttg tgatcggaat 65820
gcaatgatga cagacacaca gcttttcgaa tatctttatt tttcgccaaa aactattaaa 65880
aataaattgg tgaatcattt tgaaattttg gcaaataata atgtcttgag cgaattttat 65940
cctaagcaat acaaattaca aaaaggtgta ttcaaaggat gcagagtttt gtgtactgct 66000
cctaatgcaa gattaatgaa taaaattcca tattttacca tggaatttat tgatggacct 66060
tttaaaggac taatcaccca aagtttaatg gcatatgatt ctgagccatt tttaattaaa 66120
gaacagtctt ggataaattt attttctaat tgaggttata tgaaagcata tcaaattctt 66180
gaaggcacac ataaaggtac tatttatttt gaagatggta ttcaagcacg aattattgtt 66240
tctaaaacct ttaaagagga ctcttttgta gacccagaaa ttttctacgg tttgcacacc 66300
cgtgaaattg aaattgaatc acatcctaca gttaaaattg aaggtggtca acacctgaac 66360
gttaacgttc tgcgtcgtga aactctggaa gatgcagtta agcatccgga aaaatatccg 66420
cagctgacca tccgtgtatc cggttatgca gttcgcttta actctctgac tccggaacag 66480
cagcgcgacg ttatcgctcg tacctttact gagagcttgt aatggcaaag ataattattg 66540
aaggttctaa agatgtgtta aatgctttcg ccgagtggtt tagtaattca ggcgaacagc 66600
aatttaatga agcatggacc atgggtgata ttgatggaat ttatcctacg acagaaattt 66660
ctgttcaagg atatggcatt catgaaccta ttcgtttagt tgaatatgat ttatgtactg 66720
gtgaggaagt caaatatgat tgaagatatt aaaggttata agccacatac tgaagagaaa 66780
atcggtaaag tgaatgctat caaagatgct gaagttcgtt taggacttat ctttgacgct 66840
ttatacgatg aattttggga agcactagat aattgtgaag actgtgaatt cgcgaagaat 66900
tatgctgaaa gcctcgatca gttaactatt gctaaaacga aactcaaaga agccagtatg 66960
tgggcttgtc gtgctgtgtt ccaaccagag gaaaaatatt aatggctcaa ttaagcgcag 67020
ggtttggtta tgagtattat actgcccctc gtcgtgtatc tgttgctcct aagaaaattc 67080
aaagtcttga tgacttccaa gaagtagtcc gtaaagcttt ccaggactat gcgcgttatc 67140
ttaaagaaga ttcacaggac tgtcttgaag aagatgaaat tgcttactat gagcaacgtc 67200
ttgaacagct taaaaacctg catgaggtcc gtgcagaagt ttcaaagtct atgaataaat 67260
tgattagatt taaagaataa ctgtttactt ttcctcttga ctgtggtata atttttctat 67320
cagttaagag gagaataaca tgactatcaa cacagaagtt tttatccgtc gaaataagct 67380
tcgtcgtcac tttgagtcgg agtttcgtca aattaacaat gagattcgtg aggcatcaaa 67440
agcagcaggg gtctcatcgt ttcatctaaa atattctcag catcttcttg atcgtgcaat 67500
tcaacgggag attgatgaga catatgtttt tgaattattc cacaaaataa aagaccatgt 67560
tttagaagtt aatgaattcc tgagtatgcc tccgcgtcct gacattgacg aggattttat 67620
tgatggggtt gaataccgtc ctggacgttt agaaattaca gatggaaatc tttggcttgg 67680
atttacagtt tgtaaaccta atgcgaagtt caaagacccg tcgcttcaat gcaggatggc 67740
aattatcaac agtcgtcgtt taccaggaaa ggcttctaaa gcagtaatta aaactcaatg 67800
aggtaagcat gagaaaagca ctactcgctg gtctattggc catttcaatg atggcgcata 67860
gctccgagca tactttcagt aatgtccaac tcgataacat gcgttacgca tatcaattcg 67920
gggaacaatt ttctaaggat ggaaaatata aaacacacaa aaatatccac aagagcggat 67980
tgggtcatat aatggctgct attttgtggc aagaaagctc tgccggagtt aatttaaaat 68040
ctaaaccaaa gcatcatgcc tatggaatgt tccaaaatta tttgccaact atgcgagcaa 68100
gagttaagga acttggttat aatatgaccg atgctgaaat aaaaagaatg ttgaataaac 68160
ggtccaattc agcttcctgg gcgtacattg aactttctta ttggttaaat atacataagg 68220
gcgatataag aaaagcaata tcctcttata attcgggatg gaatgttaaa gcaggttcta 68280
aatatgcttc tgaagtccta gaaaaggcta attaccttaa aaataataaa cttttggaaa 68340
tagtaaatga ctaaaatttt ggttttatgt ataggattaa tttcattttc tgcttctgca 68400
tcagcagata catcatatac tgaaattaga gagtatgtaa atcgtactgc cgcggattat 68460
tgcgggaaaa ataaagcatg ccaagctgaa tttgcacaga aattaatata tgcatataaa 68520
gacggagaaa gagataaatc aagcagatac aaaaatgata cattgttaaa acgatatgct 68580
aaaaagtgga ataccttaga atgttcagtt gcggaggaga aagataaagc cgcttgtcat 68640
tcaatggttg accgtttagt agattcttat aatcgaggat tgagtactag atgattgtaa 68700
aatatatcaa gggcgatatt gtcgccctat ttcttcaagg taatattatt gcgcacgggt 68760
gcaattgctt ccacacaatg ggctctggcg tagcaggtca attagcaaga gcctatccca 68820
aaattttaga aatagataaa accactaccg agtacggttc tcgtgataaa ttaggcgata 68880
tgtctattgt ttttaaacat aatcctacag gatttggtat atgctataac ctgtatacgc 68940
aatatgaacc gggtcctaat cttgattatg gtgctttagt aaactgcatg atagaattaa 69000
atctacaggc agaaaccctt ttgtttaaac cagtaattta cattccacgc ataggttgcg 69060
gtattgctgg tggtgattgg gataaggttt ctaaattaat tgacatgttt actcctgata 69120
ttgatttaat agtggtggat tatgaaagta cattacccgc atccgtttga tcctaaaaac 69180
aaagtggaaa ttattcgtca atgggaacgc atttgccgta ctaaatgccc aattaatagt 69240
ccacatgatg tagataaaga ctatattgga acattcgttg aatatacctt tattgataag 69300
aaaggtcgta aacaacatgt agaagaatat tgcttaaagg ttacatggtt atgagccaaa 69360
ctagtattct taaaaatgcc cactgcgaaa agtgtgaatg gccggttgtt tttgctttat 69420
gtaatgatga aatggcttgc gatttcgatt attggtgcta ttgttctaat aaaggatgca 69480
tcaatcataa aggtgaagga ttttattcag gattttatcc ttatcctgat ttcgttaaag 69540
aaggtaaacc aaaatgaacg atgatttaaa atatcaatta ttacgtgaac ttgatgtttt 69600
gattgaactt tctgcgcaaa aaggatttat aattggatca ggtcaaaaag accccaacgg 69660
tcattcaatc gtagcggtta tgaatcagaa acgagtcatt ttaaaacttt tggggattga 69720
catactgtga gcctaagcaa agaacaaaaa gacagactat tttctcttat tcacgaagtt 69780
atggataaaa atagcgaatt ggaaaaagtt tgtgatgaat gcggtccttt taataccgac 69840
gaatacgaag aactgtgtaa agatttcgac gataaagaac aagaacttat taattatata 69900
aattccttat gattactcgc gaacaaaaga acgaaatatt atttttagtt ggtgaaatta 69960
ttagtttaga aaaggatttg tcttttgaaa tatcttctga atacggagat gccgaaacat 70020
attacgaatt agtaaaatct atcgataaag ctgaaaatga tttagaaaca tatttagaaa 70080
atttaactaa ggactaagat ggcgagttta atttttactt atgcagcaat gaatgctgga 70140
aaatctgctt ctcttttgac tgctgcacac aattataaag aacgcggaat gggtgtatta 70200
gttcttaagc ctgctattga tactcgcgat tctgtctgtg aagtcgtttc tcgcattgga 70260
attaaacagg aagcgaatat tattacggat gatatggata tttttgagtt ctataaatgg 70320
gcagaagcac aaaaagatat tcattgtgta tttgtagatg aagcccagtt tttaaaaact 70380
gaacaggtgc atcaattaag ccgaattgtt gatacatata atgttcctgt tatggcttat 70440
ggtctaagga ctgatttcgc tggaaaatta tttgaaggtt ctaaagaact tttggcgatt 70500
gcagataaac ttattgaact aaaagcagtt tgtcattgtg gtaaaaaagc tattatgaca 70560
gctcgattaa tggaagatgg aacaccagtt aaagaaggta atcaaatctg tattggtgat 70620
gaaatttatg tttctttgtg tagaaaacac tggaatgaat taactaaaaa gctcggttag 70680
tgcaaaagtt ataaataggt ttatctaact aaaggggtat atatgctaca attaactgaa 70740
aagcaacttc gcaatcttac tgttcttcaa ttagatgaaa ttcgtaggga agttggaaat 70800
atcatttcag ctttgcgtcg agaagtatca ctcaaccaat ctccggcaga ctatactaga 70860
ttgcgaaatt ttgaaaaata ccttgataaa gttaaggccg tgcatcggca taaagtaaat 70920
acaggacaaa aatgatagga ggcctttatg gccttaaaag caacggcact atttgccatg 70980
ctaggattag cgtttgtttt atctccaccg attgaagcga atgtcgatcc tcattttgat 71040
aaatttatgg aatctggtat tagacatgtt tatatgcttt ttgaaaataa aagcgtagaa 71100
tcatctgaac agttctatag ttttatgcga acgacttata aaaatgaccc gtgctcttcc 71160
gattttgaat gtatagagcg aggcgcggag atggcacaat catacgctag aattatgaac 71220
attaaattgg agactgaatg aaattcagcg acttttcaca aagtggaaaa ccttcaaagg 71280
cagatgaata cttaggttta ttaatggctg cacaagctta ttttcattct gcacattttg 71340
aaactaaaag ttatgctaga cacaaagcat acgattttat tttctctgag ttgccagatt 71400
tgattgataa atttggtgag caatatttgg ggtattctgg tagaaaatac acgccttcta 71460
ttccagatgc cagtaaactt cctaccgaca caattaaaat gattgatcgc atactagacc 71520
aatctaacag catttataaa gaaatgcctc cagccattca aagcacgata gatgatatta 71580
ctgggatgtt ttaccagagt aaatatcttc tttccctcga ataacattag tctccttcgg 71640
gagacttttt tcattttacc ggtttacttt ccatttgagc tgtgatacta tacaactatc 71700
ggataaagag gagaacatca tgaaaattga agcactcaat caagaaggaa atatctacgt 71760
catcattaat ggtgattttt tcgtcaacat ggatgaagtt actagtgaag aacttgtaga 71820
acttcttaag aaacgttatg atatgtgtga tgaagctgca actcacatgg cgtgtgcaat 71880
attctctctt tcatatgtgg tggaataatg attagcattg aacaagcaga taaaattaaa 71940
gaattggtag ctttaattcg caaagcagat gaggaactta gtgactttgc ttggttttcg 72000
tcaggcattg caaataaagg tattgaaaaa tttgaagcta aagttgataa tgctgtagaa 72060
gctttagata tgtttcttga tgaaattatc gatcataata cgagagttta agtatgctaa 72120
cacgtgaaca gtttgaaaaa atcattaaat tagcacgtga tattgaaata gattcatatc 72180
agttggcagt tgagcattgt gaaggatact catacgatgg tatagaagca gctaaaaagg 72240
atttggataa atccaaagct aagttagttc aatatcttga aatgattagg tggaataatg 72300
aaaactgaaa agcagatgtt tttaatgaag ctaattgaag aatatgctaa tgcagtttct 72360
gactatgagt attctgctcg agaaagaggt acagctttcg caaaggaaga aatgaaaatt 72420
atggttgatg ctcacacaaa gcttcagaat tttattgaaa acgtcattta atggtttaca 72480
agttggcaag gttatgatat agtaatcttg tcaactgcca aggagaagag aatgaaagtt 72540
ttgtttgttg tgtatgtgat gattcaatat aattacccaa tgtttactta taatctggtg 72600
aacaatatta ttgatattat tcaaaggagt atgtaatgac aagtgaacaa gcttttaagt 72660
taagagaatt aattgaaact ttaattggtg aataatgtga gctttccgaa attagaagta 72720
ggtgatttag tcttaacaaa attgtggaat gacgctcaat cagtagaaat ctgtcaatat 72780
cgtggagcaa caggtaattt gatgtacacg atttataacc cagaaatttt gttagagtgt 72840
catttggaac gttttataaa agacaccgat agtatgcctt atagtgtatc gattgtacgt 72900
aaatctgata caaaggaata ctctaaaatt ttaaaacaaa ttcatgccaa taaaaaggat 72960
taatatgaaa cgattagtac tagaagttag ttcacttttt ggtgaattag ctatagaaaa 73020
agtaaataat atgtatcgtt tgacgcaaga agatgatatg atgtatttta cgcctagtga 73080
aatcattcat ttaacccaaa ttgaaaatcc ttatactgat aaaattgtaa gcattaatga 73140
tgagcataaa attcattttt attcttcatg cccaggattt aatattgaaa gcgagtcaat 73200
atgcctatca gttattcatt gggacagttt tatagataag attaaatatt tttattattc 73260
taatgaaaga aaacatagtt taaaatggtt taaaaattgc aatgctatta ttactaacgc 73320
ttgcaatcag aatgatgaaa ctgttttaaa cgtatcaaaa tgttatgaag atggagatgt 73380
cttaactatt cgtcaaattg atgattttcg atcgcatatt gtcacattta ccaaagacga 73440
agctattgcg ctaaagactt atcttgattc tgtcattcca actatgattt caaagtgagg 73500
aaatatgttt atttcaagtg gaagtggttt aattcgcgtt gaatttaaaa atgacatctt 73560
ccttagtcaa ggagatgata ttattaaaat gagttatgat gaaattaaga aaatttgtca 73620
cattcttgaa agtcgtggaa aaggaaatgc tactatcgat ataggtgatt tatgggtgac 73680
actttatgaa gtatccgaag gatttaacat tgaagatgaa aacaacatct tagctattga 73740
taaaagaagc gatttgtttg atgtgttaaa agtttatgaa cagtcaaacg gtggaagaaa 73800
agctgcattg atttatcaaa aaccacattc atgcggaact gcttcaatta tttcagatat 73860
tgaagatgaa actgatactt atatgtgtgt tttaaaagct ggtggtgacc gtcatccgga 73920
ttttatttct attcgtcaaa acaatggaga aatttcatta tcaaaatcag aagctgaagc 73980
tatgattaag tatttaacaa ctgttacacc ttcaatgaaa ggataattat gattattaat 74040
gaaaactctt ggcactataa attattcaaa ctgtttaatg atgaatggaa acgacctaag 74100
acactgtgtg catacttttg gtctattgtt atccctacat ttttcgtttc ttttttcgga 74160
tgtactatac tcgcaggtct aactattatc tgtgcagaaa tcatgcagaa atggcttatt 74220
tttggtagtt tatggactct tattccatca gcatttatac ttgccatttt gcttgtttta 74280
cttattattg gttcatttgt tattcctgca caactgcatg aaaaatataa agattataaa 74340
tggaaaaagg attatgcttt acatgtagaa aatattgata gggcgtataa aggtttacct 74400
cctattcaac ccaagaaatc tattatcgtc gaatttttaa aagcgcgtaa agctaaagta 74460
tgtcctgtta ttgaatataa ggctgaatga tgaaaacagt aatgaaaagc tattttggta 74520
gtcatcttta tggaacttct actccagaat ctgatgtaga ttttaaagaa atctttgttc 74580
ctcctgctcg cgatattctt attggaaatg ttaaagagca tatgagtaaa aacactaaca 74640
acacatcatc taaaaacact aaagatgata ttgaccatga actatacagt cttaagtatt 74700
tctttaaatt agcagcagat ggtgaaactg tagcattgga tatgctccac actccaccgg 74760
aactagtagt taaatctgat ttgcctgatg tatggaagtt tattcaagac aaccgttctc 74820
gtttttatac gaccaacatg aaatcctact taggatatgt tcgcaagcaa gcttctaaat 74880
acggtgttaa gggttctcgt ttggccgcat tacgtgatgt gttgaaagta gttaatcaaa 74940
tccctgagca atgggttgat taccaagaag acggttccat taagcagcgt cgaactaaag 75000
ttgaagatat taagcatcgt cttccagaga acgaattctg tgaatgggta ttccataatc 75060
atgagaaaac aggtccacaa acgttctaca ctgtgttggg tcgtaaatat caaacaacgc 75120
tttctcttat tgagcttaag cagtctttga ataaacttga tgctgaatac ggcgaacgtg 75180
ctcgtaaggc tgaagcgaat gagggcattg actggaaagc tctgagtcat gcttgccgtg 75240
gtggactcca actattggaa atttacaaaa ctggtgactt agtctatcca cttcaagacg 75300
ctccatttat tctcgacgtg aagttgggta aacatccatt taaaactgtt caagagtttt 75360
tggaagatgt tgtcgatcaa gtagaagcag catccattga agcttctaag aacggtatgc 75420
agcaaaaagt agacatgggt ttctgggatg acttccttga gagggtttat cttgaaaacc 75480
accgaagtta ttataaatga tagggagcct tcgggctccc ttttttattt caaaattttt 75540
tcacaaaaca gtttacaagc ataaagcttt atggtactat acaactatca actgatacgg 75600
atttggagaa taaaatgaaa actgtaacta tcaataaggg tatctacttc ggtaaagaaa 75660
tctctggaac ttttgagctc ttaggcgaat ggttcccaga taatgctccg gtagatgcac 75720
aaggagatgg taaagttttt gttgaaattg acggtaaacg tcgcggtgtt tgggtttaca 75780
aatcagatat ttcatatgat ggtgtaaaag ttgaagaagt taaagaatca tatgaagata 75840
tgaaaacccg cattaataaa agatttaatg ttatgggaat gatgacgaat ggtattatta 75900
acggaaatat tcgttcatta attatctctg gcgcagcagg tattggtaaa acgtattctt 75960
tagataaagc tttaaataaa gcaaatgata ttggatacat tgaatataaa agcattaatg 76020
gtaaaatctc tggtattggt ctttatgagc agctttggaa taatcgtgaa gagaattctg 76080
tccttttgat tgatgatgta gatgttttct ctgatatgga cattcttaat cttctaaaag 76140
ccgctctgga cactggagag acccgtaaag tctgctggag cactgcgtct tcttacttag 76200
aagaaaaagg cattgagcgt gagtttgaat ttaaaggaac gattgttttt atcacaaacg 76260
ttgacattga ccgcgaatta gaccgtggta ctaaacttgc tccacattta caagcattag 76320
tgtcccgctc ggtttattta gatttgggtg ttcacactaa tgaagaaatt atggtcaggg 76380
ttgaagatgt tattctttca actgacatga tgcaaaagcg cggtctttct gatgaagaaa 76440
cttataaagc attatcatgg atgaaagtta atgttaatcg tttacgcaat gtttcactgc 76500
gtactgctct ttatcttgct gactttatta tgaccgacaa aaacggttgg gaagaaattg 76560
ctgaggttac tcttttgaaa taattcataa gaggacttct atgacaaaaa ggcagttcag 76620
aaatagatta tatggactgc cattaaaaag atgactagaa ttaaactgat gaatggaggt 76680
agtgatgtta tactcaaagg ctcgtgaaat ttacgaaact aaaattaaag aagcagtatt 76740
tcagttcgca acaacaatgc gatggacaaa tgactgggag tattcaaaaa atcataagaa 76800
gcccatggtg acaagaaagg ctcatatgtt agtgttaata gaccgtgagc agattaaagc 76860
ccgagaagcc ctccagaatc ataaaaaggc tgcctttgaa tggtttatgg ataacactgc 76920
tcctgagacc aagaaagcag tgagcgcctg gttcagtgga aaaaattgtg aaagaagtta 76980
cttttagtgg tttacaagac tgttcctctg tggtactata caactatcaa ctacggagga 77040
acagaaaatg aacgctaaag atattttcaa cttggtaaat tacaacgatg gtaaatttaa 77100
atctgaagca caaagcaagt tctttaatga catctcaatc ggaggtgaaa tcactgttga 77160
tggaggacaa atttacaaat cccgttggaa ttggatcgtt attattgatg agattggtat 77220
tgtagaaatt tataagaata cgaataaaaa tcgtacatta cactggtctc gtgatactaa 77280
cgaacagtac aaaaaggata aagcatctaa attatctcgt gtaactcaag aagatattga 77340
gttcatcaag aaagatattt taatgtatga taacttaatt gctgaagagc aagctgttat 77400
tgataaattt gacgagatta aagcttctcg tcaaattcct gattttatga aagaatcagt 77460
aaatgaacga tacactctca tttcagagcg tattgaaact tacaaaaagc aaagagctga 77520
acgccaaaat actcttcgga agtttgaaga acggttaaag acggtactcg cataaccgct 77580
ttataccaag gatggtataa tggttctaag cccttttaat tgagattatt atgaaacagt 77640
tgataattaa aagattgaat ttattgatat gttgtttatg tgtagtaatt gcatatggtt 77700
attacgcaat taatgattat atgcattata aagattatga tgttactgta gttaatacca 77760
ttacaggaac acaaggaaaa gggtctagtt tatcgtttat tgccgtatat gaactcaaag 77820
acggttatag atttagtgaa tatatttccc cagagatgta ttcttcaata gaaaaaggtg 77880
ataatattac tgtaagttta cgtcctttcg acgtaaaaca gacatggttt gataatatta 77940
tttggttctt tggaatggca ttagttcagt ctatatgcgg tacttatata gtctgttcaa 78000
tcttatttcg cgtaattagt aaaattgagt gaggaaaata tgtcagtagt aattaataat 78060
gtcaatgcag taattaaatc tttagttaat aaaaaaaatg atgaatgaat ggactgtatt 78120
tcgccgtgga gagccggata aattttttca tagatttaac ccaactttgg atttgaatgt 78180
tattgacaga gatgttcatg cagaaatttt agataagttt aaagttgata ttggatttgg 78240
attagaaaaa catttgcagc gaacaaatgg gtctggaatg agtttatcta atcgcattat 78300
gaaagccctt aataaaattg gagcattgtc tcgtattaac gcgagtgaaa tccttcgtaa 78360
ttataataaa ggatatgacc tttatggtcg actaatgcca aaattatcat tcgatcaaat 78420
gattgcggat ttgtgggaaa atcaaagacg attattagca ttaggcgctc gattagctaa 78480
aggtctagat aaacaaatga tttttaagac taataataca gaagacctta aatgctttaa 78540
atttagtact cgtggcgatg attattacat cagagctcac tctacagatt atgttaatat 78600
ggggcatcat ctctgtttag cttttgaagt tttaaaagaa tctggaacat tagaatattc 78660
atctggtgca aaatgcccta ttggttcaag ttgtatttta atttatcgcc cggatgaatc 78720
cagttcaatt acattgccta caaaacctgt accagttcat agtaacgaaa aacattttga 78780
acaaattgat tattttaata aacagattga agagctgaat atttctattc aacaatatga 78840
tgatgaaatt ttcagactat ctggactgaa tagtaaagct aaatctgagc gtgaaaagtt 78900
aattaaaatt gttgatttac ttaaatctta aggaacacca tgaaaactcg ttctcaaatt 78960
gaagatatgg ttcgtactgc cagcgatact cgtaatgtta tgacattttt gtgtgaaaat 79020
aatttagacc ctgataaagt taatcgtgct attcatcact ttaaatatct aaatagcagt 79080
gaatgggtga gtaattttag taaagcgggg tatattacac aaatgactgc tcgtgagcag 79140
ctcacagatt tctgtaaaac tattgattat aaaaatcctc tatttgttca aggcgttggt 79200
caaagtaagg tcgatttatc atctggattt ttcaatccaa atcattatcg tattgaatgg 79260
agatttattg ctctattccg taaacaatta aagcaaattt tgtcgacggc tagtcgatta 79320
aaaggttctg acattaactt aaagaacctg aaatttgatg gttatactct tcagatggaa 79380
gtaagaccat taaaagaaaa taacagaact gcacgaatta gctttaaacc taatacaaaa 79440
aattctcttt caatttgcga atgccttaaa tcgcagttga cagaagcatt taagtatatg 79500
gatgttgttg ccgctgttca gtctaagatt ttacctcgtt ttgagcgatt taaattagac 79560
acaacaacat atgaacttga tatgatcgtt tcatttaaat acgatttttt gagaaaggac 79620
gaagtcccgc aagagaaaaa gcaggaagtg caagatatct taaatttatc caattactca 79680
tcaaacgatc ctaaattttg gatgtatagc tcaagcaata tagatgcatg taaacttaat 79740
aaagtgagtt ttcttcctac tgaaaattca aattttaaac ctgtagaaaa atggcacgcc 79800
gatgcgattg agaagtctct taaggcagta gatgatgaac tcgttaaagc gaccaatgaa 79860
gtgctagaag ctgaaaaggt gttagaacaa gctcagtcaa gggttcaaaa tctgacaaag 79920
caacgttcta aactgaacaa tgcactaaat gcactgaact agtttacttt gccacaagga 79980
tgtggtataa tgttcttact ttctactgag gagattaata tgactcgtaa cgaatatatc 80040
aaatcgttca atagcgttat tgatgataaa gttaaaccta tgtctagtca gaatagtgtg 80100
atttctatta tcaatcaatg gatcaataat actagtgcaa gtattgtttc ttccgacaaa 80160
tttatttatg aagtttgtga aatttctagt cgtacatata aagatgacat taaggaaacc 80220
tttaaaggtt ctcgtcttct ttcatactta gtcaacagag atattcttag taaatttggg 80280
aaagaaatta aacgaactaa agatgtagta ggatataatt ggttcggtga tgttaattct 80340
tatcatctta ataataaaga agaccctgag aatattttta ctcgtcgttg gattagtaat 80400
ttcagacttt tcaaaggaca aattctaaaa tcagcttcta aattatgtta tggcgattat 80460
cgtcaaattc atcctttggc ttctgatatg attatcgtaa aagaaaatga gcttgataaa 80520
aataaagtag ctatttttgt gaattatgga ttttttacac caaacgctaa ccaaaagaat 80580
attaataaat ttttctcaat tgctagcact ataacttatc aattagaggc ggctttgggc 80640
tgtatggaaa ctgtaaaaag tattcataca tatcctttca aaaatatgtg tggttgggaa 80700
ggatataaaa ttataattag ccttcgtgaa gtgaaatgtg cgtactcacc gactgataaa 80760
gaaatttacc aacaaaaatg tgaagaaatt gtgaatactc ctaaagaaga aactaccctt 80820
gaggaactaa tggataatct tgatgattca cctgaaccgg tagaaattcg tccagaagtt 80880
attgcattag aaaaagctta taaggaagtt ctagaaattt ctaataaagc gcagaaagaa 80940
tatgagcagg ctaaaaggat ttgggaagaa tctgttaatc gcctggatcg tcttgaacaa 81000
gctttacaat taattaagta atttaaagcc aaggatggct cggagtataa atcattaacc 81060
aagtgagaag aacatgaaaa ctcgtaaaca ttatattgat tattttgaca gtcttattac 81120
taaacaccgt aattatcaga tcggacacag agcagtaatc aataatattc ttcgtgattt 81180
ccttcaatat gttggccagg aaaatcatat ctgtaaagat actcaaaacg cttattctca 81240
ttcgttaggc aatttgcttg aatggtttaa acgttctcgt atgttatctt ctactgtagc 81300
tcgcgataac attaaaaact ttatgaagcc gagcttcatt aaatctacga catctataac 81360
cgatttggtt gaatttacta ttgttaacga tgttaaaaag acccatttgg ctgattggtt 81420
atctaccatt cctgaaacta aatttgctga taaatttgct tgtcaattca atgcccaagt 81480
gaatatgctt tttaagcatg ctcgcaaact atttaccgca ggcgatgacc gtacaaatac 81540
agttcatgtt aaggactggg ttattgctga tgaagtaaca cacaagccag gtggttcatc 81600
agtattaatt aatatccagg ttccttatta ttactcacgt aatctcggca ccatgacagc 81660
taaagaaatt aataagcaca acaaaactat tcgttcgttg tcttataaac ttcgcatgat 81720
gttaaaaatt atggacgtag tggaaatgta tgatgaaacc gaagataatg gttcaatgtt 81780
atacagctca cgcattctaa ttaaactgaa gaaccctaat acgtataagc cagttgtaaa 81840
agaacctaaa gtagaaaagg ttgataacct gagcgaagaa cgtgaatatc tcaatgctcg 81900
tttaattgaa gttgaagccc agattgccga acacaccaaa ttgttaaaag ctcttaatgc 81960
aaaagcaaat ggtttacgta atgctattga ggtattgaaa tgaaaaagcg cttattagaa 82020
gatattgcag cttcaagtaa ttccagtcta attaaaatta ttatggctgg tgaagaagac 82080
gatctggaaa tgcgtggaaa gattcatggt tgtgacgatt tagattttaa acctccagca 82140
tgggatgcta ttatggctat ggttgaacgt cgcgaaaggg cttctaaaaa cgttcctaat 82200
tgccctgaat gcggtactga acaggttcaa ttaattcatt ggcagactag tattcttcgt 82260
tataaatgcc gtcattgcaa acaccgattt aaccgagaag aaaatgacaa agcgtaaaga 82320
atatatggag actgctgaaa aggcagtccg tgaattagca atagcgtatt ataatgaaca 82380
tggtaaattt cctgatagat acagcgtgct taaatctgct ttaactcgtt catataaaaa 82440
tatgctatca gaagtaagtg atattatata caaacataaa gaacaaacgg gccaaagtct 82500
tgattacgac gagactttta aacaagtact aggaattaag gaataatatg tttaaagtat 82560
atggttatga tagcaacatc cacaaatgtg tgtattgcga taatgcaaaa cgtcttttga 82620
ctgtgaagaa acagccgttt gaatttatca atattatgcc ggaaaaaggt gtttttgatg 82680
atgagaaaat cgctgagctt ctgacgaaac taggtcgtga tactcaaatt ggtttgacaa 82740
tgccacaagt atttgctcct gatggaagtc atattggtgg atttgatcaa ttgcgggaat 82800
actttaaatg atgctcgaaa gaactgatta tatccatgac taccgcggaa gcgcggtata 82860
tgtaggtgat gaggttgcag tttattatgg atatggaact ttgatgacag caaaggttat 82920
tcaaattaaa aatggccgcg ctaaactcga agtttattat tctaatggtg aaaagtctat 82980
ttctaaatgg aaatatggcg attgtatggt caaactgggg taaatatgat ttacgatatt 83040
agtgtatcaa gagctccatc aatggttact attccagctg aagaactgga tcgtcttcag 83100
aaaattgaag aacttctttg ggaaattgaa tctgatttgc catcaggact agaatcctgg 83160
attgattatg aagaacttaa taaattgcga aattaattgg tgaaaaatga atattgaaaa 83220
taaattagat gttgatgcag ttctgagcga aatcatcgaa gaccatgatg gattttcaga 83280
aaattatgat ttcgattttt cggattatct taaacctgtc gaaatagaag attgggtaca 83340
agatggcaaa tgccaatatc gtcagtgtgt ttattttagt ccaaaacata acgttcatgt 83400
gtctgtaaat gaaactcgct caggttctta ccattctgac tggtattatg cagttccgac 83460
tgttgaacta gtcgagcccc atgaacgtgt agtaactcag acaatacgag aatggattac 83520
gctataaaac cttggtgggc ggctagatgg gaaactgtag agccagagcc ggaagaaccg 83580
gtttacactg atgaagaaac agtatataat gaaccaacga taaacgactt aattgatatg 83640
gagatgggat atgattgcag tagataagtg gtttaaaatt aatcgtgctg ataaagagct 83700
gtgtaattac tggccggaac ttggtgcagg tactgtcttt aaagttcgtg aacttgtaaa 83760
agaatgtgaa gatgatatag aacctgatac tggaattatt gaaattgaac tttctggtgg 83820
aaagattatt aacatctacg ataagccaac tgcctattgg tgcttatgga atactgaatc 83880
agtagaaaat ggcgaaattg aagaggtcgt agaacgagtt gatcaagtta ttcggaaacc 83940
tgaagccgct tttcaaggtg aacgtatttc atacgcatta gctaaattag ctgcacaaga 84000
aaataacgat ggttatgaag gaaatttaat gcaagctgcg gcagaatata ttgaatggct 84060
tgaaactcaa aattcttttt ctgaccgagc gttttaatga aaaccgaatt aatttatact 84120
gaaaagttaa atggtggtaa ggtttggaaa ctttttatta aaggaagtca taccgactct 84180
aatatgacca cttgtgtagg aacttattct cgtcctacta aaaagatgat tcggcaatat 84240
aagcgattgc atcgaatgtt ttacaatact tgaaaataat aaataccctt atctattcaa 84300
ggtaagggtt ttattatgtt attgactggc aaattataca aagaagaaaa acagaaattt 84360
tataacgcac aaaacggtaa atgcttaatt tgccaacgag aactaaatcc tgatgttcaa 84420
gctaatcacc ttgaccatga ccatgaatta aatggaccaa aagcaggaaa ggtacgtgga 84480
ttgctctgta atctctgcaa tgcagcggaa ggtcaaatga aacacaaatt taatcgttct 84540
ggcttaaagg ggcaaggcgt tgattatctt gaatggttag aaaatttact tacttattta 84600
aaatccgatt acacccaaaa taatattcac cctaacttcg ttggagataa atcaaaggaa 84660
ttttctcgtt taggaaaaga ggaaatgatg gctgagatgc ttcaaagagg atttgaatat 84720
aatgaatcta acactaaaac acaattaata gcttcattta agaagcagct tagaaagagt 84780
ttaaaatgac aattgaaaaa gaaattgaag gattgattca taaaactaat aaagaccttt 84840
taaacgagaa tgctaataaa gattctcgtg tttttccaac tcaacgggac cttatggctg 84900
gtattgtgtc taaacacatt gccaaaaata tggtcccgtc ttttattatg aaagcgcatg 84960
aaagcggaat tatccatttc catgatattg attattcccc tgctcttcca tttactaatt 85020
gctgtttagt agatttaaaa ggaatgcttg aaaacggatt taagctcggc aatgcacaga 85080
ttgaaactcc taaatcaatc ggcgttgcca ctgcaattat ggcacaaatt actgcacagg 85140
ttgcttccca tcaatatggc ggaacgactt ttgcgaatgt agataaagta ctttctcctt 85200
atgttaaacg cacctatgca aaacatattg aggacgcaga aaaatggcaa atcgctgatg 85260
cgttgaatta cgcccagtct aaaacagaaa aagacgtata cgatgcattc caagcttatg 85320
aatatgaagt aaatactctc tttagttcaa acggacaaac gccttttgta acaattacat 85380
ttggtacggg aactgactgg actgaacgaa tgattcagaa agcaattctg aaaaatcgta 85440
ttaaaggtct tggtcgcgat gggataactc ctattttccc taagcttgtt atgttcgttg 85500
aagaaggcgt taatctttat aaagacgatc cgaactatga tattaagcag cttgctctag 85560
agtgtgcaag caaaagaatg tatcctgaca tcatttcggc taagaacaat aaagctatca 85620
ccggttcatc tattcctgtt tctccaatgg gttgtcgtag tttcttgggc gtatggaaag 85680
attcgactgg taatgaaatt cttgatggac gtaataatct tggcgttgta acactgaatc 85740
ttcctcgtat tgcgttagat tcttatattg gaacacagtt caatgaacag aaatttgccg 85800
aattgttcaa tgaacgaatg gatttatgtt ttgaagcatt gatgtgtaga attagttcct 85860
taaaaggagt taaagctact gttgctccta ttctttatca agaaggtgca ttcggggttc 85920
gtcttaaacc tgatgacgat ataattgagt tatttaaaaa cggtagaagt tcagtgtccc 85980
taggatacat tggtattcac gaattgaata ttcttgtcgg tcgtgacatt ggacaagaaa 86040
ttttaactaa aatgaatgca catcttaagc agtggactga aagaactggt tttgctttta 86100
gcttgtattc tacacctgct gaaaacttgt gttatcgctt ctgtaaactc gataccgaaa 86160
aatatggaag tgtaaaggat gttactgata aaggctggta cactaacagt ttccacgttt 86220
cagtagaaga aaatattact ccgtttgaaa agatttctcg cgaagcacca tatcatttca 86280
ttgcgacagg tggtcacatt tcttatgttg aacttcctga tatgaaaaat aacctaaaag 86340
gtcttgaggc tgtatgggat tatgctgcac aacatttaga ttattttggt gttaacatgc 86400
cagtagataa atgttttacg tgtggaagta cccatgaaat gactcctact gaaaacggat 86460
ttgtttgttc tatttgtgga gaaactgatc ctaaaaagat gaacacaata agaagaacat 86520
gcggctattt gggaaatccg aatgaacgcg gatttaatct cggcaaaaat aaagaaatca 86580
tgcatagggt taaacaccaa tgaattatga tagattttat ccttgcgatt ttgtgaatga 86640
taaattatct ttaatatttg aagaaaataa tgatttacta ttgtcatatg ttgatttgat 86700
aacaaaaaat tataataatc ctaaaataaa aggaaaaacg gaagcacatc acgtgcttcc 86760
caaatctata tttcccgaat ataaaacaga taaatggaat attgttaatt tgtcatatta 86820
tgaccacgcg ttagctcatt actatttagc taaaacaagt aatagtaaaa tgtgttatgc 86880
ctttcataga atgataaact cgaataccga tagatttaat acagatgaat tggatgaaat 86940
tcttaaattg tattccagtg aaaaggaatt atttcaccgc tctatgtcaa aattatcgaa 87000
aaatatatgg aaggatgacg attttagaaa aagacataga gaactaacta agttagcaat 87060
gcaaaaacct gaagttagaa ataaaacttt attaaatttg tcaaatgcaa tgaaaactga 87120
cgaagttaga aataaaattt ccaggctaac taagttagca atgcaaaaac ctgaagtaaa 87180
agaaaaacat agaaattcat tgaggttggc gtatgcaaat cctgaggtta tgaaaagaaa 87240
acatcaacgt cttcgagaaa aatatactct taatttattt ggcgcatata aagatggtgt 87300
tcttttaaaa acatttaatt atataccaga cgcagcaaaa tattttaata tttctagcaa 87360
aggaaatatt ttaaaatgtt taaatggcga acgtaaaagt gttgaaggct ataattggaa 87420
atatataaat gaattatgac agaatatacc cgtgctgctt tgtgaatggc cctggatgca 87480
ggaccgttct tttcgttacc ggttgtttgc ataaatgcga agggtgttat aataaatcaa 87540
cgtggaacgc tagaaatggt gttccattca cgggtgaaac actagaacaa ttaattgaat 87600
gtttgaataa tgattatata gaaggattaa ctataactgg aggagaccct ctctatcctg 87660
ataaccgaga tgatgttcat tgcattgttc aaacagtaaa aaatctttat ccaaataaaa 87720
gcatttggtt gtggacagga tataagtttg aagatattaa acaactagaa atgcttaaat 87780
atgttgatgt tattattgat gggaagtatg agaaaaatct tccgactaaa aagctgtggc 87840
gaggatcaga taatcagcga ctttggtcaa ataccgatgg ggtgtggaaa catgattaaa 87900
ttgaattata ttatggacac tataaatgat atgatttttc attttggtcc agaattttat 87960
tcgcaatata gtttagtgct tatcaatgct tggttaatca attaagggta aaatatgtat 88020
aaatttcgca aaggtttagc tgattttctt acaactgtaa cattctttct gtttatggca 88080
gttggagcta ttttccttat tccttttatt gctatatttt tcgtgattag tttgatttct 88140
ccagaaaaag gactgtcttc tagcgagttc aatgagcgtc tggataaaat tactaataag 88200
ctgaatgctg ctcttagtaa ggaatagttg tgaaacagaa caagattgaa gtctatggaa 88260
ttccagatga agtaggtcgt tgtcctggat gtcaatcagt tacaaaactt ctaaaggagc 88320
tcaatgctcc ttttactttc tataaagttc ttacaaataa tggtaagatt gagtatgatc 88380
gtccactgat tgtatctctt gctaaacgcg ctggattcac atctcttaac attcgttatc 88440
cagtcatttt catcaatgat tctagacaaa agaacattaa acacttcaaa gaaactctca 88500
tttcacttgg atatgataga gatatcatag aagactaaga tgggccctct gggcctttct 88560
ttctcacatt ctgtatatta ccattctaac tatcgttccc ttcttatcat tccctaaaat 88620
aattttcaca aagttgttta caagaagttc aaactgtggt attattaaca catgaattgc 88680
ctttgaggaa ttgatatggt tgtggttgat aaagaaatta aaaagggaca gtattatttt 88740
attaatggta atgttgttcg tgttacttat gtaaacggtt ttgaagttta ttatcttata 88800
ctcaagttac ataaacagat gatttgtgac cgtgctgtat ttagttcagt tgctaaggaa 88860
attaaactcc atgggtaaaa catatcgtcg taaagattta aaagtacgtg attatgacta 88920
tttcggaaag cgtaaagctc ctgatggtgt aagtcataaa gatatggttg aaaacatttt 88980
tcgctctgat aaatggcgta gaatgaaagg cattgattca gaagttaaag atgagttaaa 89040
tcgtcaattg cgcggtgaag taagaaagtt gaaaaaatca gtttacattg acgatgattt 89100
tgattacaat acttcccaac gagttgctaa gcgcaaatca aacgagtgtt atcgttacag 89160
ctgaggaaaa tatgaatatc aaacgcatgc tttttaaaca aggattatac actttaaatg 89220
ttgctccaaa aggcgatacg accaagtggt cagtaaatga ctggattaaa tttattgatg 89280
aaaatggtaa ctggaaaatt taaatgaatc ctgaatctaa attatcgcaa cgaattgctg 89340
aagctcgtcg tcagttcttt gaaaatatga tagcccaagg tattgatgac gaaatttttc 89400
taaactggtt ttggaatcac aaatattcaa aatgcgcagg agcaatatta atatcagccg 89460
caatgatgta tgaaggctgg aagggtgcca aacagtttag ctaagggctt cggccctttt 89520
tggataataa aattttaatg taattgagga taatgtatga ctattcaaat taaaaacgcc 89580
atcaattctt acgcatatga taaagtagtt tctttgctag aaaaaggcga tattgtaact 89640
cctcaaattt tggataaatg ggaaaaagag cttcatcaga cgatgaaaca gaatgatcag 89700
aaaattggtc gcaatactgt ccgtgaattg ttggttcaat atatcttgtc agaatttgat 89760
gttaaagctt ttggcgtaga atctaaagct tatcaaaagc atgaaatttc cgataaaact 89820
attcgtcgta tgaaaaatca acgcaagaaa aaatttgctg acctgaaaat tgctaaggta 89880
tgaatatgaa cgaagctctt attaacgatt tgcgtcttgc cggatatgaa gtaaatacaa 89940
acggcattgg tttaactcaa attgaaggaa atggattcat ccttgagtat gaatttagcc 90000
aatggtggtt atacgctaat tatggcgaat tgattgaata cgttgaccag tttgattcac 90060
tagatgcagc tcttgaagcg gctaagttga tgaatgcatg aaatttatta atatttctat 90120
tactattgaa aattatggca ttttctatgt tgatcaatac atgaaaattt catttttccc 90180
aaataagact ggtgttggat attgggaaag ccatgtttct gaattaaatg aaagtgaata 90240
tgctagcaca catgaaaagt ttttagactt tttatatcat gctgatttaa ctagtcatta 90300
tatagatatt catgaattta aaaagatgat ggagaaagtg ttccaggcat actgcttact 90360
tagataactg atatcctcta tgctttaaga tagatcttca aatattatga tataatagat 90420
ctatgaattg agctaagagg tgaaaatgtc agaaactaag cctaaatata attacgtaaa 90480
caataaagag cttttacaag ctattattga ttggaaaaca gaattagcaa ataataaaga 90540
cccaaataaa gtagttcgtc agaatgatac tatcggattg gccattatgc ttattgcaga 90600
aggcttatct aaacgtttca acttttcagg atacacccaa tcctggaaac aagaaatgat 90660
tgcagatggt atagaagctt ctattaaggg gcttcataat tttgatgaaa cgaaatataa 90720
aaacccacat gcatatataa ctcaagcttg ttttaatgca ttcgtccaac gtattaaaaa 90780
agaacgtaag gaagttgcaa agaaatacag ttacttcgtt cacaatgtct atgacagtcg 90840
tgacgacgat atggttgcgt tagtagatga aacttttatt caagacatct acgataaaat 90900
gacgcattac gaagaatcaa cctatagaac accgggggct gaaaagaaaa gtgttgtaga 90960
cgattctcct agtttggatt ttttatatga ggctaacgat taacctctcc ggattcttgg 91020
aagaaatacc tgaagttgaa gctattccct atttacttaa aatgtatctc agggaagttt 91080
tagctcttga cattgatatt gatccagaaa atccgtatga taccgctttt aaatctaatg 91140
gtgtagaatt aaactatcgg tatcatttaa cagatgatga tttttatttt atattagaga 91200
aataatatga ctgataaacc cgaaattaat gatgaagtgg aaaagcttat ttcttctatt 91260
gaagaaaaga accgtcttga agcagaaaga aaagcaaata agttattgtc taaaaacaaa 91320
cgcgaactga accgtcttta taagcacgct cagattgcag ctgaaaacaa taattttgct 91380
caatacgaat atgctatcaa gaaaagtcgg gatattctaa aacagccata taacgatgaa 91440
ctcattagta ttctttggaa gactactaga tcgcagattg aggatatgat tgatgcttac 91500
acacgtaaaa ttcaagcgtc ttaaaattaa tgcaggattt actgaatctt tgaatggtca 91560
tctttgtgtg aaaatttctg aaaaagaata ccacgatagt tcaattaaag aagttaatcc 91620
tcctattgta agagcagacc ctaatatgaa agtgtgggtt gattcttatc aagtcaaaaa 91680
atggtggcaa ctgtgaaaga tgaacaccca gacttctgaa atagattata ataaaattcg 91740
ttcctctaaa gtagaaatga tgagacgctt taaagagtct catgataaag ctaaagcaga 91800
aggaactata acatataagc gtataaaatt tagaagctct aatgagcctc tgtatggtgt 91860
attatgcgga taggagcttc ggctcctata ttgctttata aatttttggt aaaataaacc 91920
aaaacaatga ggatattaaa tgaaagtatg catttttatg gctcgaggtc ttgaaggttg 91980
cggcgtaact aaattttctc tcgagcaacg tgattggttt attaaaaatg gtcatgaagt 92040
aactttggtt tatgctaaag ataaatcatt tacccgtaat tgcgcgcatg attataaatc 92100
attttcaatt ccggttttat tggcaaaaga atacgataaa acacttaagc tggtaaatga 92160
ttgtgatatt ctaattatta attcagttcc tgctacttca gtagaagaag acactattaa 92220
taactataaa aaaattattg ataacattaa accttcagtt cgtgttgtag tttatcaaca 92280
tgaccattct tctctttctt tgcgccgaaa tttgggatta gaagaaactg ttcgtcgagc 92340
tgatgttatt tttagtcatt ctgataatgg cgattttaat aaagttttga tgaaagaatg 92400
gtatccagaa acggtttctc tgtttgatga tattgaagaa gcaccgaccg tatataactt 92460
tcagcctcct atggatattg cgaaggttcg atcaacctac tggaaagatg tttctgaaat 92520
taacatgaat atcaaccgtt ggattggtcg tactactaca tggaaaggct tttatcagat 92580
gtttgatttt cacgaaaaac atcttaaacc tgctgggcta agtactatta tggaaggtct 92640
ggaacgttct ccagcgttca ttcctattaa agaaaaagga attccatatg agtattatcg 92700
tcttcatcaa gtagaccaaa ttaaaattgc tcctaatttg ccaacgcaaa ttcttgaccg 92760
ttatgtaaat agcgagatgc ttgaacgcat gagtaaatcc ggatttggtt atcagttgag 92820
taagttggac aaaaaatatc tacaacgttc tttagaatat actcatctcg agcttggtgc 92880
atgtggaaca attccagtat tttggaaatc tactggtgaa aatttaaaat tccgcgttga 92940
taatactccg ctaatttcac atgatagtgg tatcgtttgg tttgatgaaa atgacatgga 93000
atcaacattt gagcgtatta aagaactgtc atctgaccga actctttatg accgtgaacg 93060
cgaaaaagct tatgaatttt tgtatcagca tcaagattca agcttctgct ttaaagaaca 93120
atttgacatt attacaaaat aaagggcttc ggccctttag ctttatacgg agtttgatat 93180
aatgatattt cttggatatg tgatactttt tctcgcattt tatctattca ctagagcatg 93240
ttggattggg ttctttagca ctccagatgg atttatttca ataattttat tttgcatttc 93300
aatgacggtt cttgatatat gaaaatttta aatttaggtg attggcattt aggtgttaaa 93360
gccgatgatg agtgggttca atccattcag ttggatggaa ttaaacaagc aatagaatat 93420
tctaagaaaa atggaattac tacatggatt caatacggcg atatttttga tgtgcgaaaa 93480
gcaatcacac ataaaactat ggagttcgct cgtgaaatag ttcaaatgct tgatgacgct 93540
ggaatcacat tacatactat tgtaggaaat cacgatctcc actacaaaaa tgtaatgcat 93600
ccaaatgcct ctactgagct tttggctaaa tatcctaatg ttaaagtata tgataagcct 93660
gctacagtag attttgacgg atgtttgatt gatttaattc cttggatgtg cgaagaaaat 93720
actggtgaaa ttcttgaaca catcaaaact tcatctgctt ctttttgtgt tggtcactgg 93780
gaactgaatg gattttattt ttataaagga atgaaatctc acggtcttga acctgatttc 93840
cttaagactt ataaagaggt gtggtctggt cacttccata ctatctctga ggctgctaac 93900
gtcagatata ttgggacacc atggacacta actgcaggtg acgagaatga ccctcgcggg 93960
ttctggatgt ttgatacaga aacagaacga atggaattta ttccaaacaa caccacctgg 94020
catcgtcgaa ttcaatatcc atttaagggg aaaattgact ataaagattt tacaaatcta 94080
tcagtacgtg ttatagtaac tgaagtagac aaaaatctaa cgaagttcga atccgaacta 94140
gaaaaagttg tgcattcatt acgagttgtg tcaaagattg ataactctgt cgagtcagat 94200
gatagtgaag aagttgaagt tcaatctctt cagacgttga tggaagaata cattaatgca 94260
attccagaca tcactgattc tgatcgcgaa gcacttattc aatatgcaaa ccagttatat 94320
gtagaggcaa cacaatgact tttgatgaat ttaaaaatgt tatgatgagt cagcattttg 94380
aatgcgaagt aaaagatgat attgggcata aagaaattat tgaatattgg tttgaaccgc 94440
tagaggttga agataattgt attaaaaagg ttacggtctg cactgattgg gccgtatctt 94500
ttaacttcaa cattttagat aatgacacac ctaaatcatt acaagatatg gctgtatctt 94560
gtattaagga tgcatactgt gaagttttcg acatttgaca ttaacgatga attcatagca 94620
aatattgatt acaccgaaga agattctaga tatgttggaa taatttatat cacatcaaaa 94680
gcagcacaag gtgttgtttg catggctgaa tttgatgaat actttttaga ttatgatgat 94740
atgatagaat ggtctaaaag atacattaaa aggaatcttt tgtgaagaat tttaaactaa 94800
accgagttag gtatcaaaat ataatgtcag taggtggaaa tcctattgac attcaactag 94860
ataaggttca aaaaactctt attactggac gaaatggcgg tggtaagtct actatgttag 94920
aagccatcac atttgggctt tttggcaagc catttcgtga tgtaaagaaa ggtcaattaa 94980
taaacagcac aaataagaaa gaacttttag ttgaactgtg gatggaatat gatgagaaaa 95040
agtactatat caaaagagga caaaaaccaa acgttttcga aatcaccgtt aacggtacac 95100
gtcttaatga atctgccagc agtaaagatt tccaagcaga atttgaacag cttatcggaa 95160
tgtcatatgc cagtttcaag cagattgttg tccttggtac agcagggtat acccctttca 95220
tgggtttgtc aacccctgca cgaagaaagc ttgtggaaga cctgctcgag gtaggaacat 95280
tagctgaaat ggataagctt aataaagcac taatacgtga attaaattca caaaaccaag 95340
tgcttgatgt taaaaaagat agtattatcc aacaaattaa aatatataat gataacgttg 95400
aacgccagaa aaaattaact ggtgataacc ttactcgtct acagaatatg tatgatgatt 95460
tggcaaaaga agctagaacg ctaaaatcgg aaatagaaga agctaatgaa agattagtta 95520
atattgtttt ggatgaagac ccgactgatg catttaataa aatcggccaa gaagcatttt 95580
taattaaatc aaaaattgac tcgtataata aagtcattaa tatgtatcac gaaggtggat 95640
tatgtccaac ctgtttgtca caattaagtt ccggtgataa agttgtttct aaaattaaag 95700
ataaagtttc tgaatgcacg cattcgtttg aacagctttc aacacatcgt gataatttaa 95760
aagttctcgt cgatgaatac cgagataata ttaaaaccca acagacgttg gcaaatgata 95820
ttcgcaataa aaagcaatct ctaatcacga ctgtagataa agctaaaaaa gttaaagcag 95880
ctatagaaaa agcatcatcc gagtttattg accatgctga tgaaatagca ctgcttcaag 95940
aagaacttga taaaattgtt aagacaaaaa ctaatttagt aatggaaaaa taccacagag 96000
gaattttgac tgatatgctc aaagattctg gtattaaagg tgctattatt aaaaagtaca 96060
ttccattatt taataagcag attaaccatt atcttaaaat aatggaagca gattatgtgt 96120
ttacattaga tgaagaattt aatgagacaa ttaaatcccg tggtcgtgaa gattttagtt 96180
atgcttcatt tagtgaaggt gaaaaagcgc gaattgatat tgctctttta tttacttggc 96240
gtgatattgc ttctatcgta tctggtgtta gtattagtac attaattctt gatgaagtgt 96300
ttgatgggtc atttgatgcc gaaggtatta aaggtgtagc taatattata aattcaatga 96360
aaaatactaa tgtttttata atttcgcata aagaccacga cccgcaagaa tatggtcagc 96420
atcttcaaat gaagaaagtt ggtcgattta ctgtaatggt ttaatttata agagattatg 96480
ctttaattta ttagagtata atctctatgg aggaaaaaca tggaatattc aactggacag 96540
catctattaa ctattcctga aataaaacga tatattctga gaaataattt ttctaatgaa 96600
gagcatatag ttactgaatc tatgcttaag aatgcattta aatcagaata tacgaaaata 96660
atgtccaaca ggaatgaagc ttggactgtt actgattatt atgactaaag gtgtattatg 96720
actaaaatta ctgtgaatta tactgttgat gtaaaagata ttcagccaaa acacgtgcgt 96780
tctgaatcaa atccgcaaaa ccaaaataaa attcgtcgag catgggtttt gtctctttct 96840
gataacgcaa tggaagttat tcagaataaa attaaatctg cacctgctcg tcatgcgtat 96900
tatgaagcta tcgatcgtga agtgagtgat aaatggattg aactaatgcg caaacatacg 96960
acagaatctc taaatgctgg tgctaaattt attatgactt catgcggtga acgccttgaa 97020
gatgattatt gcggtaatgc agatgaacgt ctaattgttg ctgctcaaat tgttgcagaa 97080
acaattgctg ctgattttaa tcgttaattg ctttattaaa ttagttataa aattaaatct 97140
catttgaatt gaaggaaatt acatgaaact gtctaaagat actactgctc tgcttaaaaa 97200
tttcgctact attaactctg gtattatgct taaatctggt caatttatta tgactcgcgc 97260
agttaatggt acaacttatg cggaagcaaa tatttccgac accattgatt ttgatgtagc 97320
aatttacgat ttgaacggtt ttctcggtat tctgtcccta gttaatgacg atgcagaaat 97380
ttcccagtca gaagatggaa atattaaaat tgctgatgcc cgttcaacaa ttttttggcc 97440
tgcagccgat ccgagtacag tagttgctcc taataaacca attccattcc cggtagcatc 97500
tgttgttact gaaattaaag ctgaagacct tcaacagctg ttgcgtgtat ctcgtggtct 97560
gcagattgat acaattgcta tcacagtaaa agaaggtaaa atcgtaatta acggttttaa 97620
taaagtagaa gattctgctt tgactcgtgt taaatattct ttgactcttg gtgattatga 97680
tggtgaaaat acatttaatt tcattatcaa tatggcaaat atgaaaatgc aaccaggaaa 97740
ttataaactt ctgctctggg caaaaggtaa acaaggtgct gctaaatttg aaggtgaaca 97800
cgcgaattat gtagtagctc ttgaagctga ttctacccac gatttttaat agagggcttc 97860
ggccctttat aatttacact aaaacttgaa tgaggaaatt atgattactg taaatgaaaa 97920
agaacacatt cttgaacaga aatatcgtcc atctactatc gatgaatgta ttcttcccgc 97980
ctttgataaa gaaaccttta aatctattac aagtaaaggt aagattccgc atattattct 98040
tcattctcct tctccaggaa caggtaaaac aactgtagca aaagcattgt gtcatgacgt 98100
aaatgctgat atgatgtttg tgaatggatc agattgtaaa attgatttcg ttcgcggtcc 98160
tttgaccaat tttgctagtg cagcttcatt tgatggccgt caaaaagtaa tcgtcattga 98220
tgaatttgac cgttcaggat tagcagagtc tcagcgacat cttcgttcct ttatggaagc 98280
ttatagttca aactgtagca ttattattac tgctaacaat attgatggta ttattaaacc 98340
acttcagtca cgctgccgag ttattacatt cggtcaacca accgatgaag ataaaattga 98400
aatgatgaag cagatgattc gtcgattgac tgaaatctgt aagcgtgaag gaattgctat 98460
agctgatatg aaagttgtag cagctttggt taaaaagaat tttcctgatt ttcgtaaaac 98520
tattggagag ctcgatagtt attcatctaa aggtgttttg gatgctggta ttttatcact 98580
ggttactaac gatcgtggtg ctattgatga tgttcttgag tctctcaaaa ataaagatgt 98640
taaacagctc agagctttag caccaaaata tgcagctgat tattcgtggt tcgtaggtaa 98700
acttgccgaa gaaatctata cacgcgtaac tccacaaagt attattcgta tgtatgaaat 98760
tgttggtgaa aataaccagt atcacggaat tgcggctaat actgaattac atttagcata 98820
tcttttcatt caattagcat gcgaaatgca gtggaagtga tatgagctta tttgaagatg 98880
atattcaatt aaacgagcat caagttgctt ggtattcaaa agattggaca gctgtccaat 98940
ctgctgctga ttcttttaag gaaaaagctg aaaatgaatt ttttgaaata attggagcta 99000
ttaataataa aactaaatgc tctattgctc aaaaagatta ttcaaaatac atggttgaga 99060
atgcattatc acaatttcct gaatgcatgc cagctgtata tgctatgaat ttaattggat 99120
caggtttaag cgatgaagcc cattttaatt atctgatggc tgctgttcct cgtggtaaaa 99180
gatatggtaa atgggcaaaa ctggttgaag attctactga agtattgatt attaagttac 99240
ttgctaaacg gtatcaagtt aatacaaatg atgcaattaa ctataaatca attcttgcta 99300
aaaatggaaa acttccttta gtattaaaag aactaaaagg tttagtcacg gatgattttt 99360
taaaagaagt gactaagaat gtaaaagaac agaaacaact caaaaaacta gcattggaat 99420
ggtaaaatga ttgaaattac tcttaaaaaa cctgaagatt ttctgaaagt aaaagaaact 99480
ttgactcgta tgggaattgc taataataaa gataaagttc tgtatcagtc ctgccacatt 99540
cttcagaaaa aaggactata ctatatcgtc cattttaaag aaatgcttcg tatggatggc 99600
cgtcaggttg aaatgacaga agaagatgaa gttcgccgtg attcgattgc gtggctgtta 99660
gaagattggg gactgattga aatcgttcct ggtcaaagaa cttttatgaa agatttaacc 99720
aataacttcc gagttatttc ttttaaacaa aaacatgaat ggaaactcgt tccaaaatat 99780
acgattggta attaagcaag gggcttcggc cccttatttg gagtataata tatcaagagc 99840
ctaataactc gggctataaa ctaaggaata tctatgaaag aattttatat ctctatcgaa 99900
acagtcggaa ataatattgt tgagcgttat attgatgaaa atggaaagga acgtactcgt 99960
gaagtagaat atcttccgac tatgtttagg cattgtaagg aagagtcaaa gtacaaagac 100020
atttatggta aaaattgcgc tcctcaaaaa tttccatcaa tgaaagatgc acgagactgg 100080
atgaaacgaa tggaagacat tggtctcgaa gctctcggta tgaacgattt taaactcgct 100140
tatatcagtg atacatatgg ttcagaaatt gtttatgacc gaaaatttgt tcgtgtagct 100200
aactgtgaca ttgaggttac tggtgataaa tttcctgacc caatgaaagc agaatatgaa 100260
attgatgcta tcactcatta tgattcaatt gacgatcgtt tttacgtctt tgatttgttg 100320
aattcaatgt acggttcagt atcaaaatgg gatgcaaagt tagctgctaa gcttgactgt 100380
gaaggtggtg atgaagttcc tcaagaaatt cttgaccgag taatttatat gccatttgat 100440
aatgagcgtg atatgctcat ggaatatatt aatctctggg aacagaaacg acctgctatt 100500
tttaccggtt ggaatattga gggatttgac gttccgtata tcatgaatcg tgttaaaatg 100560
gttctcggtg aacgtagtat gaaacgcttc tctccaatcg gtcgagtaaa atctaaacta 100620
attcaaaata tgtacggtag caaagaaatt tattctattg atggcgtatc tattcttgat 100680
tatttagatt tgtataagaa attcgcattt actaatttgc cgtcattttc tttggaatca 100740
gttgctcaac atgaaaccaa aaaaggtaaa ttaccatatg atggtcctat taataaactt 100800
cgtgagacta atcatcaacg atacattagt tataacatca ttgacgtaga atcagttcaa 100860
gcaattgata aaattcgtgg gtttatcgat ctagttttaa gtatgtccta ttacgctaaa 100920
atgccttttt ctggtgtaat gagtcctatt aaaacttggg atgctattat ttttaactca 100980
ctgaaaggtg aacataaggt tattcctcaa caaggttcgc acgttaaaca gagttttcca 101040
ggtgcatttg tatttgaacc taaaccaatt gcccgtcgat acattatgag ttttgacttg 101100
acgtctctgt atcctagcat tattcgtcag gttaacatta gtcctgagac tattcgtgga 101160
cagtttaaag ttcatccaat tcatgaatat atcgcaggaa cagctcctaa gccaagtgat 101220
gaatattctt gttctccgaa tggatggatg tatgataagc atcaagaagg tatcattcca 101280
aaggaaatcg ctaaagtatt tttccagcgt aaagattgga aaaagaaaat gttcgccgaa 101340
gaaatgaatg ccgaagctat taaaaagatt attatgaaag gtgcagggtc ttgttcaact 101400
aaaccagaag ttgaacgata tgttaagttt aatgatgatt tcttaaacga attatcgaat 101460
tacaccgaat ctgttcttaa tagtctgatc gaagagtgcg aaaaagcagc tacacttgct 101520
aatacaaatc agctgaaccg taaaattctt attaacagtc tttatggtgc tcttggtaac 101580
attcatttcc gttactatga tttgcgaaat gctactgcta tcacaatttt tggtcaagtt 101640
ggtattcagt ggattgctcg taaaattaat gagtatctaa ataaagtatg tggaactgat 101700
ggtgaagatt tcatcgcagc aggtgatact gattcggtat atgtctgtgt agataaagtt 101760
attgaaaaag taggtcttga ccgctttaaa gaacaaaatg atttagttga attcatgaat 101820
cagttcggta agaaaaagat ggaacctatg attgatgttg catatcgtga gttatgtgat 101880
tatatgaata accgcgagca tctgatgcat atggaccgtg aagctatttc ttgtcctccg 101940
cttggttcaa agggcgttgg tggattttgg aaagcgaaaa aacgttatgc tctgaacgtt 102000
tatgatatgg aagataagcg atttgctgaa ccacatctaa aaatcatggg tatggaaact 102060
cagcagagtt caacaccaaa agcagtgcaa gaagctctcg aagaaagtat tcgtcgtatt 102120
cttcaggaag gtgaagagtc tgtccaagaa tactataaga actttgagaa agaatatcgt 102180
caacttgact ataaagttat tgctgaagta aaaaccgcga atgatatagc gaaatatgat 102240
gataaaggtt ggccaggatt taaatgtccg ttccacattc gtggggtgct aacttatcgt 102300
cgagctgtta gtggtttagg tgtagctcca attttggatg gaaataaggt aatggttctt 102360
ccattacgtg aaggaaatcc atttggtgac aagtgcattg cttggccatc aggcacagaa 102420
cttccaaaag aaattcgttc tgatgtactg tcttggattg actactcaac tttgttccaa 102480
aaatcgtttg ttaaaccgct tgcgggtatg tgtgaatcgg caggtatgga ctatgaggaa 102540
aaagcttcgt tagacttcct gtttggctga tagaataaat ctagggacct ccgggtccct 102600
ttttcataca agtaatataa atctatactt aggaaaaata gatgattctg gacctctgga 102660
attcattaaa aaatttttca caaaatggtt tacaagactg ttcctctgtg gtactataca 102720
actatcaacc aatacagatt tggagaatga aatgaaaatc gctattttag ttattgcatt 102780
gggtcttact ggttgtgtag ctcaaggacc agtagtaaat cagtctgatg caggaaaaat 102840
tgtaaactgt tcaagcaaat tttataatcc taacgtcaag tgttataaag aagctccaaa 102900
acagacagta gaagaaatgc aggcgaattt tgacgaagct attcgtccag atgaatctgc 102960
tcaagcatat cgtaattcag atgtgattac gcgtgaagaa aaaattgaaa actactgcgc 103020
tgaactttgg gctaattggg ctaataatta ccaatggcgt actggtaaaa atgctccgat 103080
ggagtatgta gtaaattctt acaattcatg cgtaaaaaat ttgactaagt gaggaaacat 103140
ggaaacttta gtagcaggtt caatttttat ggttttagtt tcaggcgtgt tggctattat 103200
tatatacatg cttccgtggt tcatcgcctt gatgcgtggg tcaaaatcga cagtaggaat 103260
cttttttaca tctttactgt ttaactggtc aatcattggt tggtttatta catttatttg 103320
gtcaattgcg ggtgaaacta aaaagtcaac acagccaaat caagtaatta tcatcagaga 103380
gaaggaatga aaagcaaaat tataacagtg ttgcttttaa tcttgatgat tataataagt 103440
atatactata gtgtaacggt tcctcttatg attccaacgc ttattatagg gtggagttta 103500
ttactgttac aagttaaata tgaatgtatc aattgaggtt taaatgatta atgactctat 103560
gacagttgaa gaaattcgtc ttcatttggg aattgcatta aaggaaaaag attttgtaat 103620
tgacaaaacc ggggttaaaa ctattgaaat tattggtgca tcatttgtag cagatgaacc 103680
ttttattttt ggtgctctta atgatgaata cattcagcgt gaacttgaat ggtataaatc 103740
taaaagtttg tttgttaaag atattccggg tgaaacgccg aagatttggc aacaggtagc 103800
atcttctaaa ggcgaaatta actcgaatta tggttgggcc atctggtcag aagataacta 103860
tgcccagtat gatatgtgtt tagctgaact tggtcaaaat cctgattctc gacgcggtat 103920
catgatttat actcgtccat ccatgcagtt tgactacaat aaagatggta tgtcagattt 103980
catgtgtacg aatacagtac agtacctgat tcgtgataag aaagtcaatg cagtagtaag 104040
catgcgttca aatgacgtag tcttcggatt ccgtaatgat tatgcatggc aaaaatacgt 104100
actagataaa ttagtatctg atttgaatgc aggtgattca actcgtcagt ataaagcagg 104160
ttccattata tggaatgtcg gaagccttca tgtgtattcc cgtcattttt atttagttga 104220
ccattggtgg aaaactggcg aaactcatat tgcgaaaaaa gattataacg gtgagtggaa 104280
atgattcaat tcgtaattcc aagctatcaa cgcgtagggg cagtttctgc ccttgatatg 104340
tttccatctg attatgaacc gcatattgta gtacgtgaac atgaagaaaa agcttattat 104400
gacgcttacg ggtctagagc caaaattata actattcctg atgatgttaa tggaattgct 104460
ggcactcgta aagcaattac tgatatgtat gcaggtcaac gaatttggat gattgatgat 104520
gatactacta ttcgtatgag ttcaatgcga aaaagagatg accgtcgttg tgtagataaa 104580
gtcaatcaat taacccgtga acagttctat gaattgattc aatacgtcga agatgccatg 104640
gattgcgggt attatcatgg ccatgctcgt ctacctattt ttaaaattac ttcatcttgg 104700
ggtaattatc gtgaaaattc atatggattc acgaatacat ggtatgacct cggaaaactt 104760
acaacagaac aaattgggta tggaaaaatt gatttatgcg aagatatgta tgcatttctc 104820
aatttaatta atcaaggtta tccgcatttg gccctgttca aatatctggt tgtatctgga 104880
aaagcgcaag ctccgggcgg gtgcagttca attcgtagta attcaaaaca taatagagct 104940
cttgagcaaa tcaatagaga gtttccagag caagctcgtt ggaaaacatc gaatattgaa 105000
aagagaaaat cgttgggtga agaagacgag ccattaaagg ttcttcgcat gtgtgtttcg 105060
cgcaaagaaa aatcagaagc gtttcataag tttaatgcta ttcatccaat agcagttgat 105120
taatgcctaa atttattgtg ttataattac tttatcttta accagtgagg aaaatataat 105180
gatgcctatg gaaaaaatga atgtctattg cagatttaaa atcccgtttg attaaagctt 105240
ccacttctaa aatgactgct gaactgacta catctaaatt ctttaatgaa aaggatgtaa 105300
tccgtacaaa aatcccaatg cttaatattg ctatttctgg tgcgattgat ggcggtatgc 105360
agtctggttt aactattttc gcagggcctt ctaaacactt taaatcaaat atgtctttga 105420
ctatggttgc agcgtatttg aacaaatatc ctgatgcagt ttgtctattc tatgatagcg 105480
aatttggtat tactccagct tatttgcgat ccatgggagt tgacccggaa cgagtaattc 105540
atacaccaat ccagtcagtt gaacagctga aaattgatat ggtgaatcag cttgaagcta 105600
ttgagcgtgg tgaaaaggtt attgtattca tcgactcaat tggtaatatg gcttctaaga 105660
aagaaacgga agatgccttg aatgaaaaat ctgtggcaga tatgactcgt gctaaatcac 105720
tgaagtcatt attccgtatt gttactcctt attttagcat taaaaatatt ccatgtgttg 105780
cggttaacca tacaattgaa accattgaaa tgtttagtaa aaccgtgatg acaggtggta 105840
caggcgtaat gtattcagct gatactgtat tcattatcgg taagcgtcag attaaagatg 105900
gttctgatct tcaggggtat caatttgttc taaatgtaga aaaatctcgt accgttaaag 105960
aaaaaagtaa attctttatt gatgttaaat ttgacggtgg tatcgatcct tattctggat 106020
tgttagatat ggctcttgaa ttaggatttg tagtaaaacc taaaaatggc tggtatgctc 106080
gtgaatttct tgatgaagaa accggcgaga tgattcgcga agaaaaatct tggcgtgcaa 106140
aagataccaa ttgcactaca ttctggggtc ctttatttaa gcatcaacca ttccgagatg 106200
ctattaaacg tgcttatcag ttaggtgcta ttgatagtaa tgaaattgtt gaagctgaag 106260
ttgatgaatt gattaactca aaggttgaaa aatttaaatc tccagaaagt aaaagtaaat 106320
cagcagctga tttagaaact gacctagatc agttaagtga tatggaagaa tttaatgaat 106380
aaagatgatt tagatttaga tctagaaatt atcgacgaat ccccctcttc ggagggggaa 106440
gaagaaagaa aagaacgcct ttttaatgaa tctcttaaga taattaaatc tgccatggaa 106500
aatgttatcc aggagattgt cattaaacta gaagacggtt ctacacacat tgtgtatgtg 106560
acaaaattag attgggttga tggaaaagtc gtaatggact ttgctgttct tgaccaagaa 106620
agaaaagctg agttagctcc tcatgtagaa aaatgtatta caatgcaact acaagatgca 106680
tttaataaaa ggtcaaagaa aaaatttaaa ttcttttaag gagtaagtgt ggtagaaatt 106740
attctttctc atctcatatt tgatcaagct tatttttcaa aagtttggcc atatatggat 106800
tcagaatatt ttgaaagtgg tccagctaaa aatacattca aattaattaa atctcatgtt 106860
aacgagtacc atagcgttcc atctattaat gcgttaaatg ttgcgctaga aaatagttca 106920
tttactgaaa cagaatattc tggtgtaaaa acacttattt caaaactggc cgattctccg 106980
gaagaccata gctggttagt aaaagaaaca gaaaaatatg ttcagcaaag ggcgatgttt 107040
aacgccacat ctaaaataat tgaaattcaa accaatgctg agcttcctcc agaaaaacga 107100
aataagaaaa tgccagatgt aggtgctatt cctgacatca tgcgccaagc attgtcaatt 107160
tcatttgata gctacgtcgg tcatgattgg atggatgact acgaagcacg ttggctatct 107220
tatatgaata aagctcgtaa ggttccattt aaactcaaaa ttctaaataa aattactaaa 107280
ggcggagctg aaactggaac actgaacgtt ttaatggctg gtgttaacgt tggtaagtca 107340
ttaggattgt gttcattggc agcagattat ttgcagctcg gacacaatgt tctttacatt 107400
tccatggaaa tggcagaaga agtctgtgct aagcgtattg acgctaatat gctcgatgtt 107460
tctcttgatg acattgatga cgggcatatt tcttacgctg agtataaagg aaaaatggaa 107520
aaatggcgtg agaaatctac tcttggccgt ttaattgtta aacagtatcc tactggtgga 107580
gcagacgcta atacatttcg atcgctttta aacgaattaa aactcaagaa gaattttgtt 107640
ccaacaatca ttattgtcga ctatctaggt atttgtaaat cttgccgcat cagggtttac 107700
tcagaaaata gttacacaac tgttaaagct attgcagagg aattgcgtgc tcttgctgtt 107760
gaaaccgaaa ctgttctttg gactgcagcg caggttggta agcaagcttg ggactcttcc 107820
gatgttaaca tgagcgatat tgcagaatct gccggtcttc cagcaacagc cgattttatg 107880
cttgcggtca ttgaaaccga ggagttagca gctgctgaac aacaactcat taagcaaatc 107940
aaatcacgat acggtgataa gaataaatgg aataagtttt tgatgggggt tcaaaaagga 108000
aatcagaaat gggtagaaat tgaacaagat tctactccaa ctgaagtgaa cgaagtagca 108060
ggttcacagc agattcaggc tgaacagaac cgctatcaaa gaaatgaatc ggctcgagct 108120
cagttagatg ctttggcaaa cgaattaaaa ttttagttta caagccgaca agactatggt 108180
atagtagtct tgttggttaa atgaggagat tgttatggaa ttggtaaagg tagtttttat 108240
ggggtggttt aagaatgaaa gcatgtttac taaagaaatc gcaatgatga aagatgacgt 108300
tcaatgggct actactcaat atgctgaagt taataaagca ttagttaaag ctttcattga 108360
tgacaagaaa gtatgtgaag ttgattgtcg aggataatat gcatattgtt ttatttaaac 108420
ctactccata tagtgttagg aaaaatactc aattcaaagc acttatcgca gatacgtggg 108480
aattggtatt agatattcca gcagaagaaa gccctccatt tggtcgagtg gaatttatta 108540
agtttgctgt gcgccctacg aagcgacaga ttcgccaatg caaaagatac tttcgtaaaa 108600
tcgtcaagtt agagaaacag tttgtaacgt gtgattatac agaagtttta aaataactgt 108660
ttacttttat tggaaaatga gatattatat aaacataaac tactgaggag attattatga 108720
aaaaatttat ctttgctgca atttttgctt tatcttcttg cgctgctcag cctgctatgg 108780
cgggttatga caaagatttg tgtgaatggt ctatgactgc agatcagact gaagttgaaa 108840
ctcaaattga agcggatatt atgaatatcg ttgagcgtga tcgtcctgaa atgaaagctg 108900
aggtgcaaaa acagcttaag tctggtggtg taatgcagta taattatgtt ctgtattgcg 108960
ataaaaactt taataataaa aatatcatcg ctgaagtggt aggtgaataa ttagaggtta 109020
atatgtatag ttctgaattt ccatatttaa aaatggaaaa aatttcatac gattttatag 109080
atgaaaaggt ttattacagt tttcatgagc cgcgttttaa cagtgaagtc ggttttattg 109140
tagtaaaaga taatttcatt ttaaaaatat attcggcatt aaaggatttt cactacgaaa 109200
atattaacct aaaatttgat aaagaaaacg ttcgtaattg cgcagtaaca attacaggaa 109260
ataaaggtac atgtgttatg ctatctgatg aaattaatga tttgctaaat aatgcagaaa 109320
agattaccat tccatctatt gatgaccaaa tttttaatgc ttttatgaat agaggttaat 109380
atgaaaacat ataaagaatt tattaaagaa gatatggtag ctggagattc aggtggtaat 109440
cctgaaaata tctctactgg aacaacgtca ggtgctgtag taaataaagg tcctgaacag 109500
attcctaaaa agaaaaaaga ggaatctaaa gaaaaagaag agtaaaaatg tcatcaatac 109560
cttggattga taatgagttt gcgtatcgtg cattagctca tttacctaaa ttcacacaag 109620
taaataatag ttcaactttt aaattgcggt ttagatgccc tgtttgtgga gattcaaaaa 109680
ccgaccagaa taaagctcgt ggatggtatt atggtgataa taatgaagga aatattcatt 109740
gttataactg taactatcat gcaccaatag gaatatattt aaaggagttt gaacctgatt 109800
tatatcgtga gtatatcttt gaaataagaa aagaaaaagg taaaagtcgt ccagtagaaa 109860
aacctaaaga acttcctaaa caacctgaga agaaaataat taaatctctt ccgtcatgtg 109920
ttagattaga taaactggcg gaagaccatc caattataaa atacgtaaaa gctcgttgta 109980
ttccaaagga taaatggaaa tatctttggt ttacaactga atggcctaaa ttagttaata 110040
gtatagcacc aggaacatat aaaaaggaaa tacctgagcc tcgtcttgtt attccaattt 110100
ataatgctaa tggaaaagct gagtcttttc aaggacgcgc attaaagaaa gatgctcctc 110160
aaaaatatat caccatcaaa gcttatcctg aggcaacaaa aatctatgga gtcgaacggg 110220
ttaaagatgg tgatgtatat gttctagaag gacctataga ttcgcttttt attgaaaatg 110280
gtatagctat tacgggcggt caattagacc tagaaattgt tccatttaaa gatagacgtg 110340
tatgggtttt ggataatgaa cctcgtcatc ctgacactat taaacgaatg actaaattgg 110400
ttgatgcagg agaaagggtt atgttttggg acaaatctcc ctggaaatca aaagatgtta 110460
atgatatgat tagaaaggaa ggtgcaaccc ctgaacaaat tatggaatat atgaaaaata 110520
atattgccca ggggttgatg gctaaaatgc ggttatctaa atatgctaag atttaaatta 110580
acccaactaa agcaaatgct aaatctacga atgtatcaag agtaactact ggaatattaa 110640
taccatgtgc aattgcaatg ggtgataaaa taaagttcca gagtaaaatt cctaccatag 110700
cagaaatagt aaaagctata cgttttttat taccttttat ggcatcaaca agtgccatta 110760
atttttgtgc catgtgtcct cctttaaatt aatatttatc ataaatttgt ttactttctc 110820
agcttgttat gatattataa aataaattgc tgaggatgat atgatgatta ataaaattgt 110880
gcatgaaatg gctttaaatg gagattcata taaaatatct gccgtagttg aaaatttcat 110940
acttaataaa gtaaaagaat atttcactga ttgttcagtt agttatcaag aaaaaatggt 111000
tttaaccgat gatactgaaa aatcaaataa tttgttttgt tctaatttta taactaagaa 111060
gcgtactaga agatttgata ttgttatttc tcgcaacggt aaaaagcata taattgaaat 111120
taaacatcaa gttggtggag gtacagctat tgattcggtt ggaatatatt tagaagataa 111180
agagaaatta aaagaataca caaaaactga aaaccctgtg tcattgatga tattagattt 111240
tttgccatgc ggatattatc cacgtaataa atggacaaaa agagaatcat ttactgataa 111300
tccaactatt caggcgaggt ttaatgaata tgctaaatca caaaacgtgt tagtattact 111360
atcaaataca tatgatgaag aattgtataa ttcatttttt gctgcaataa atgagagaat 111420
ataatgctag gagctatcgc gtatacaggt aataaacaat cattattacc tgaacttaag 111480
cctcactttc caaaatatga cagattcgtg gatttatttt gtggaggttt atcagtgtct 111540
ttgaacgtca atggtcctgt attggccaat gatattcaag aaccaattat tgaaatgtat 111600
aagcgtctta ttaatgtatc atgggatgac gttttaaaag taataaagca atataaacta 111660
tcaaaaacat caaaagaaga gtttttgaaa ttacgtgaag attataataa aactagagat 111720
cctcttttac tttatgttct tcattttcac ggatttagta atatgattcg tataaacgat 111780
aaaggaaatt ttactactcc gtttggaaaa agaactataa acaaaaatag tgaaaaacgc 111840
tttaatcact ttaaacaaaa ttgtgataaa ataatcttta gttcattgca ttttaaagat 111900
gtcaaaattc tagacggcga ttttgtatat gtggaccctc catatcttat aacagttgct 111960
gattataata aattttggtc agaagaagaa gaaaaagacc ttttaaatct tttagattct 112020
ttaaatgaca gaggaataaa atttggactg tcgaatgttt tagagcatca cggaaaggaa 112080
aacactcttc ttaaagaatg gtctaaaaaa tataatgtta agcatcttaa taaaaaatac 112140
gtctttaaca tatatcattc caaagaaaag aatggaactg atgaagtata tatttttaat 112200
taattgctta cataatcaaa tgatataatt atttaactta ttaatgaatt gaaaggaaaa 112260
ataatggctt actttaacga atgtagtcaa ctgatcgaag gcgctgataa agctcaaaat 112320
gaatactggg atattctcgg tgatgaaaaa gacccgctgc aggttatgct tgatatgcag 112380
aaatctttgc aggttcgttt agcaaatgac cgcgaatact gctaccatcc agataaatta 112440
gaaactgccg gtgatgttgt ttcttggatg cgtgaacaaa aagactgtat tgatgatgaa 112500
ttccgcgaac ttctgacttc tcttggtgaa atgtcacgtg gtgaaaaaga tgcatctgca 112560
gtttggaaaa aatggaaagc acgttatatt gaagcgcaag aaaaacgcat tgatgaaatg 112620
tccccagaag atcagcttga aattaaattt gagcttgtgg atatatttca tttcgtatta 112680
aatatgtttg ctggccttgg aatgaatgcg gaagaaatct ttaaacttta ttatttgaaa 112740
aataaacata attttgaacg tcaagataat gggtattaaa caaaaatttt atagaacata 112800
tatagtaaaa gttaggacgc cgaaaggcgt cttttggtac gctgggaaac atgaatcatt 112860
tattgtaaat ccatatgatg ataaatatcc gggttcaggc aaaatattat ggaacatata 112920
tcgtaagtat ggttttaatt ataaaatacg ttggtcaaaa tgccatggtt ctagagaaaa 112980
atcatatgaa gttgaacgcg agctaatatc tgcattaaaa cgtaaacacc cagatacttg 113040
cattaatatt tctcctggtg gtcagggtgg agaaggaaga aaatggactg agcaacaacg 113100
attagaacat aaacttagat taaacaaccc tgaaacaaaa actcggatga agaattcaca 113160
acgtatagcc caaaatagag cagaacgaaa agctcggcaa tctgaagtaa tgaaaaagtt 113220
ttattcgaat ggcggaaata aaaagatttc agaaggaact tcaagggcgc aaagaaaagc 113280
accgcattgg catgaaccgc ttaaaagcga aatacacgag ttatgggttt ctttaggtaa 113340
accagcaaca ggcccggttg taaaggcgct taaaggaaaa tatgatgtaa caagttcagc 113400
tcttaagaat ttaatttact tattcagaaa agaagatgta taaataatca tgtaatttaa 113460
ataaaaggag aattacatgg ctagtactcg cggttatgtt aatatcaaaa catttgagca 113520
gaaattagat ggaaataaga aaattgaagg aaaggaaatt tccgtagctt tccctcttta 113580
ttctgacgtt cacaaaattt ctggtgctca ttaccagaca ttcccttcag aaaaagcagc 113640
atattctaca gtatatgaag aaaatcaacg tactgaatgg attgctgcaa atgaagattt 113700
gtggaaagta actggtgaat aaattcaagg actccttcgg gagtcctttt tcattttacc 113760
ggtttacttt ccaaaatgag tatggtataa tagaattatc ttatagagga gagcgctatg 113820
ttaaatcgct ggattaaacc aaatgaagac ctccagaagg ttcttgataa agctatctct 113880
gataaatggg gcatgaaaag ctgggattgt gatatcgtca cgcattcatt catgatgcat 113940
gcagatggtt cagtcgagtt caatgctgaa atgcgataca ctgactgggg tggatttcaa 114000
agaatcgaat ttcaaagagg ctttttgtaa tgtttatctt taattggttt aaaagtttct 114060
ttacggattt tttctctacg actcctgggg aaggtgtagt tcctatttca aatgactacc 114120
ttcctttaac tgtagttgag tatgtttata tgggagatgg aacagtagaa gcagttacta 114180
tgacttatga agaagcccaa gaatattata aaaatccttg gcgctggtca gtacctacgt 114240
ctgcaccatc taatacacag tctagttctg attcatatga tactaatgtt cctgttcatg 114300
tatgggcggg cgattcatgt ggaagttctt gtgattctag ttgttcatct acatcttgtg 114360
attgaggaaa attatggaag cgattttgtt tgaaatgtat attagcagta atagcatgtc 114420
gtttgctaaa gatgttccaa ttaccgtagc agtaatgatt gataagggtt attgtgaccc 114480
aatgtatctc gtagaaaatt tcgtttcaat gccagttcca gaagatgctg aaataaaact 114540
taaaaagatt agtattattg aaactgtgcc aaatattccg tttagagcaa ttgaagcatt 114600
tactaaatcc gaatacatta atgttagcgc agaacaatat aatgataaac ctttatcatt 114660
ttattcatac gattcagtat atagttggaa aatagataaa ggaaataaat ttataattgc 114720
gagtgaagac gctttatcat attttatttc ttctgtatgg aatagtttac atccaaattt 114780
gctaaaaatt catgaatttg acgatgctcc tactgtcgtt ttaggtaaaa caaatgaaag 114840
ttctgaagaa aatacttgaa tggtttagta gaccaaactc aatgtacatt gatgatggtt 114900
gggttgaaca agcaaataaa gaaatgcaga acgaatcgga agaatggatg aaatcaatga 114960
ttagtgctga gaaagaaaag aaattagaac gctcagcgct taaattgatg agagacatct 115020
atggtgataa atcatgaaca aagatatgac attggaagag gctaaagcaa aagcaaatga 115080
agcactggat ttgcttctta aaattggcag taaaatgatg gaagaaaatg agaaatatat 115140
ccaggaaaac aaaattcccg atggtccatt agtaggcaaa aggaaatcac atgattgaag 115200
tagcaaaaca ttattcaata gaatttatgt ctaaagaagg taaatcagta aatacacttg 115260
ataaaaaatg ctcattaatt attcctttag cagaaaatcc ggatttttta attgaagata 115320
taaaagaaag aaaatatcca gaaaatgtta ttctaattat aaaacatact gaagatattt 115380
tgcaggatac tgattcaccg ttttcttctt ctgaagcttt aattattaaa ggctataaaa 115440
gagttcatga atatggtctt tttgacctgt ttgaagacga taaagttaaa ttagcgagtc 115500
aaccttcaaa aagtaaaaca ttcattattg aagatattaa agatataaat gcatttgtta 115560
agatggtctg ggctcatttt gacgttggac tacgctggag aatgtccgaa gaagaaagaa 115620
agattattga agctaatcgt caatttggtt tttatcgcta ggaattaata tggatttatt 115680
tgagatgtta gaagataatc attctacgaa tatccagaat gattctagtg attataagaa 115740
agagtaccgt atagtattac agaattatgg aattgaagcc ccagatgctc ttctagaaga 115800
actagcttca taccatcttg accctccgcc ctgggctccc tgggcaaaat aattcaaaaa 115860
gttgtttact ttcctttcta acgatgatat gatagcttct gaagtatacg gaggctatca 115920
tgattattaa tcttgcagat gttgaacagt tatctataaa agctgaaagc gttgattttc 115980
aatatgatat gtataaaaag gtctgtgaaa aatttactga ctttgagcag tcaattcttt 116040
ggcaatgtat ggaagctaaa aagaatgaag ctcttcatca gcagttgaat aaaatcgtta 116100
aaaagcattt aactaaatca ccttatcagt tatatcgtgg tatatcaaaa tcgacaaaag 116160
aacttattaa agatttacaa gttggagaag tgttttcaac gaacagagta gattcattta 116220
ctactagttt gcacacagca tgtggttttt cttatgctga atatttcact gaaacaatac 116280
ttcgtttaaa aactgataaa gcttttaatt attctgacca tatcagcgat attatacttt 116340
cttctcctaa tactgagttt aagtacacgt atgaagatac tgatgggcta gattcagagc 116400
gtactgataa cttaatgatg attgtacgtg aacaagaatg gatgattcca attggaaagt 116460
atagaataac ttctatttca aaagaaaaat tacacgattc atttggaaca tttaaagttt 116520
atgatattga ggtagttgaa tgaaatactc agtaatgcaa ctaaaagatt ttaaaataaa 116580
atcaatggat gcatcggtgc gtgcttctat tcgtgaagaa ttactttctg aagggtttaa 116640
tttatctgaa attgaacttt taattcattg tattactaat aaaccagacg atcattcttg 116700
gttaaatgaa ataatcaaat ctcgtttggt tccaaacgat aaacctcttt ggagaggtgt 116760
tccagctgag actaagcaag tattaaatca aggaattgat attattacat ttgataaagt 116820
cgtatcagct tcatatgata aaaatatagc tctacatttt gcttctgggt tagagtataa 116880
cacacaagtt atttttgaat tcaaagctcc tatggtattc aatttccagg agtatgctat 116940
aaaagctcta cgctgtaaag aatacaatcc aaactttaag tttccggata gccatcgtta 117000
tcgtaatatg gaattagttt cagatgaaca agaagtaatg ataccggctg gaagtgtatt 117060
tagaattgca gatagatatg agtataaaaa gtgttcaaca tacactatct atactcttga 117120
ttttgaagga tttaatctat aatggaagga cttagattca ttataccatg aaagttttaa 117180
agcatttttc ataaagttgt ttacaagtta aagtaaaaat gttatagtat aagtagttaa 117240
ccgtccgtaa gatgtgagaa aaatatgaag ctgtctaata accaaattcg taaaattaaa 117300
cgtcgtctag agcatactca ggcatctgca aaaagacgtt ctaaagattt taacttagac 117360
ttcaattaca ttaagaacat tttagatcag aaagtttgtg cttactcagg agaacctttt 117420
gataatcgta ttgaaggaga gaaattatca ttagaacgtt ttgataataa cgttggatac 117480
attaaaggga atgttattgc agtaaagaaa aagtataata catttcgttc tgattatact 117540
ttagaagagt tgattgaaaa gcgtgattta tttgctttgc gaattggtcg ttcatctgcg 117600
aaaaaagttc ataaactaaa tttagatgaa aagaaatggg ctaaaatcaa aaagacttat 117660
aatcaaatta aagctataca gaaaaaacgt gaaaaccgaa ttgaacacat ttctcagctt 117720
tctaaatcaa aacagacctc tgacattaag ctaagaatta tagcactcaa agctcgtatt 117780
gatggttctc gtatagcaga aggcgctgaa gttgttaaat tgaacgttct tcttaaaggc 117840
tcggattgga aaaccgtgaa aaagttgtca gaagcagaaa tgcaatatga tatgtgtgat 117900
aaaattattc aaggtgtaga gcggtatcaa aacttgtctt ttattgataa acttaaactg 117960
aaaagaggat acccgctaaa ttgttcaatt tttaaactta tccgaggata atatgtttta 118020
tgtatatgcg atagtgtata gagataaaga tggatttgtg gtgcctgttc ctcttgatga 118080
acatcgtcct gctgtatttt ttgaaaggga gattgctgat aaagtattta ctactcttaa 118140
agagcagtat caactagctt taggtatggg aattccgaga ttagttgaga ctccacgcaa 118200
gttttggttt aataaaatag aagttaaaca cgttaagcct gatgtagaca cgcaaagatt 118260
atatcggcga attttagata ctgggcgtat tgttagtata ccaattgcag ggaatttacg 118320
atgacatttg atgatttgac tgaaggccag aaaaatgcct ttaacactgt tatgagggct 118380
attaaagaaa agaaacatca tgtaactatt aatggacctg ccggtactgg taagactact 118440
cttactaagt tcatcattga agctttaata tctacgggcg aaactggcat tattttagca 118500
gctcctactc atgcggctaa aaagattctt tcaaaactgt caggaaaaga agcgagtact 118560
attcacagta ttctcaaaat taacccagta acatatgaag aaaacgttct ttttgagcaa 118620
aaagaagtac cggatttggc taaatgcaga gtattaatct gcgacgaagt gtcaatgtat 118680
gatagaaagc tatttaaaat tctgctttca actatcccgc cgtggtgtac tataattgga 118740
ataggtgata ataagcagat tagacctgtt gacccaggag aaaacactgc ttatatcagt 118800
ccattcttta cacacaaaga tttttatcag tgtgaactca ctgaagttaa acgcagtaat 118860
gctcctatta ttgatgtagc tactgacgtt cgtaacggta agtggattta tgataaaatt 118920
gttgacgggc atggagtacg tggatttact ggtgataccg ctttacgcga ttttatggta 118980
aattattttt caatcgtcaa atctctagat gatttgtttg aaaatcgcgt aatggcattt 119040
acgaataaat ctgttgacaa gttaaatagc attattcgta aaaagatttt tgaaactgat 119100
aaagatttta ttgtcggtga aattattgta atgcaggaac cattaattaa aacatataaa 119160
attgatggaa agcttgtgtc agaaattatt tttaataacg gacaattagt tcgtattata 119220
gaagcagagt atacatcaac ctttgttaaa gctcgtggtg ttcctggaga atatctaatt 119280
cgtcattggg atttaacagt agaaacttac ggcgatgatg aatattatcg tgaaaagatt 119340
aaaataattt catctgatga agagctgtat aagtttaact tatttttagg taaaacggca 119400
gaaacttata aaaattggaa taaaggcgga aaagctccgt ggagtgattt ttgggatgct 119460
aaatcacagt ttagtaaagt gaaagcactt cctgcatcaa catttcataa agctcagggc 119520
atgtctgtag accgtgcttt tatctatacg ccttgtattc attatgcaga tgctgaacta 119580
gctcagcagc ttctttatgt tggtgtaaca cgtggtcgtt atgatgtgtt ttacgtatga 119640
ttaaattcga ggaagctatt cgtggaaata actaaagatc agttttatct gctccaagat 119700
aaagtaagcg aaatttatga aatagcttat agtaaaaatc gcaaaaacgt gaaaattgaa 119760
tcaggcaagt taatgcttca attggaagaa attgaacgag atttgattgc gttagaattc 119820
ttttgcggtg aagtgaaaac tgttacaatc agtgattaca ttttaggtga aattagccat 119880
ctttataagg cggttattaa tgattgaatt aagttggtgt cagtttaaat ttcttatgac 119940
aaatgttaaa gctgtcattg agaaaaattc tggtcctgaa aatattacta ttcgcgaaaa 120000
agctttaaag ataatataca gtcttgaaga gatgcaaaaa gatattgaat ctatggcaaa 120060
atttattgat gaacctatta ataaagttta tattcaagac tatactgtag gtcaaattcg 120120
cgatttagca aggaaaattt aatgtttgat tttattatag attttgaaac aatgggaagt 120180
ggtgaaaaag cagcggttat tgatttagct gtaattgctt ttgaccctaa tccagaagtt 120240
gttgaaacat tcgatgaact agtttcacgt ggcattaaaa tcaaatttga tttaaaaagc 120300
caaaaaggac atcgtctttt tactaaaagc actatcgaat ggtggaaaaa tcagtctcct 120360
gaagctcgaa aaaatattgc accatcagat gaagatgtaa gcactatcga tggtattgca 120420
aaatttaatg attacatcaa tgcgcataat atcgatcctt ggaaatctca aggctggtgc 120480
cgtggaatgt cgtttgattt tccaatttta gtcgatctca ttcgcgatat tcaacgcctt 120540
aatggtgtat ctgagaatga gcttgacaca tttaagttag aaccatgtaa attctggaat 120600
cagcgtgata ttcgtaccag aattgaagca cttctgcttg ttcgtgatat gaccacatgc 120660
ccccttccaa agggaacttt agatggattt gttgcgcata attctattca tgactgtgcg 120720
aaagacatcc tgatgatgaa gtatgctttg cgatacgcta tgggtcttga agatgctccg 120780
tcagaggaag aatgcgatcc tctgtctctt ccaacaaaac gataaaaagt tgtttacttc 120840
ctcggttagt tgtggtatta taacaccata gctactgagg ataataaaat gaaaatttat 120900
cgtgttgaat catcgtttag tattcttaat aatgaagatg ctataacaat acgtcgaaat 120960
ctttgcgttc aaataacgcc atacaggagt ataatagatt catggagcga agagtggcta 121020
ttacacgtag gttatgacag acctaatttt atgcatcata gcgataataa taaaagaatt 121080
cctttaccac acgaagataa actattagtt aaaaacgcta atatagtaat taatactaag 121140
ttcaagaaag attatgttgg agtagaatat catattcctg gatggtttat agctctttat 121200
cattttgctt tcgctagcga atatgatatg atgagatggt tcacacgaga agagcgggaa 121260
gaattatctt ctaaaggatt ttatctcgct gtatacgaag ttcctgaaga tgaagttatc 121320
attggtgggc accaagtaat gttccgcaaa tcgcatgctg aactcgtaga ttttattgaa 121380
atgagataat tatgaaattt aattataatc ctgaatacac accgaatcct gtagataaac 121440
tgattgattt tgatgttgta agcacttatg tatgccctat taaaccactg gaaattaagg 121500
aacctactat gactaccgct attgaaatcg gcaaaaccta caaactggtt gaacctaaaa 121560
ttaaaactaa tgccttgatt tctggtcata aaactctgac tgatgttttt ggcgaaggcg 121620
aatttattgt tgaagaattt gccaaaagtg agtggtttga caaatcttac gtcatccacg 121680
gtcgccggtt agataataac aaaataaaga aaaacctggt ttatgaagat gagttcatcc 121740
tgttccaaga agttgaagaa caagacccta cagacctgtt gtgtgctgct gtgtctatcc 121800
gtcgtccttt tgataatcct atctgtggtt gggtaacaga ccagtggatt gaagatggtg 121860
ttgagcttct gaacgttgtc catgcaggag attttagtgt agtacctcgt agtgcggtgg 121920
tagctatttt gaattaatag tttacaaact cttgggacca gagtataatg gtcctgtgga 121980
gtataaaatc tttttaacaa gtgagagata actatgatta ttaatattgg tgaaattgct 122040
cgtgtatctg ataaatcccg ttctaaagca gcaggaaaat tggtcgaaat tgtaagcatt 122100
cagcttaaac acggcgttaa agatgaagat tctgaagtaa aagtgcgtat cattcctaaa 122160
gatggaaagt ctaaacctca gtttggctat gttcgtgcga aatttcttga atctgcgttt 122220
ttgaaagctg ttcctgctaa aggaattgaa acgattgata cttcgcatgt aggtgtagac 122280
tttaagtgga aactcggtca ggctattaag ttcgttgctc cttatgaatt cgaatttact 122340
gaagatgagg aaggggttgt tcaaaaacac catactcgcg ctatgtgtgc atacattact 122400
gatcaatggg tagaagatgg tgttaagctg tacaatgcgg tatttttagg aacatacaaa 122460
gtcattcctg aaagttggat taaacactat agcaaagctc gctgtgcata aagtttaaaa 122520
ttttttcata aaactatata catcagtagt tgattgtggt actatatcaa tatcaactac 122580
tgatacagaa aacaacttga agaataaaat ggataattcg ttaaaggtgc gctgatactc 122640
ttctgaaacg catcgctcca atgttcaatt aatgaggaaa ttatgatgaa acgtaaaatt 122700
gttcagaatt gcactaatga tgaatttgaa gatgtattat tcgatccaga tttggtagta 122760
gttcaaaagg aacatactag caagtttact cacttgactt ctgtttatgt gtatgagaaa 122820
gtcggtgata aacaaccaat ttatggtgta tttcgtgaaa ttactgaaaa tggcacaact 122880
tattggaagg aaatttatta atggctatta aatttgaagt taataaatgg tatcaattca 122940
aaaataaaca agctcaagaa aattttatta aagaccatac tgataacgga atctatgcgc 123000
ggcgtttagg tatggaacct tttaaaattt tagatgttga ctattacggg cgtcctacta 123060
aaattgtgac atctactggc atagttggat attcatcacg aggtacagtc attgacgaaa 123120
actttatctg gctttctagc aacgaagccg agttctttaa tgaagtggaa aatccatatc 123180
aggctactga agagcaggaa gaccctgcac cagtaactga accatctgaa ttcccggtaa 123240
tgaaagttac tattgaaaat aatgaacaag catggtcctt gtatcagatg ttgaaagctc 123300
actttaagga ataattatgc cgctttatga ttataaatgc caatccgaag actgtgcaaa 123360
agaatacgaa aaaatcaaga aaatttctga aagagatact gatgtatgtc ctgattgtca 123420
tcggattgct attcggttag tttccgctcc taagcatgtg aacggtggat tttacgactt 123480
acttaaaggg taattatgaa atatgttaat cgttctatcg cggcattagt attagcagta 123540
tctttagtag gatgtactga tgctgataat gcaaccaaag ttttgtcttc aagcggtttt 123600
actaatattg aaatcactgg atataattgg ttcggttgct ctgaaaatga tttccagcat 123660
actggatttc gtgctattgg acctactggg cagaaagtag aaggaacagt atgttctgga 123720
ctattcttca aggattcgac tattcgtttt aaataaaagg ccttcgggcc tttagcttta 123780
tgattattgg agtataatat tcccgaaacc aaacgaggat aagtgatgat taagaatgaa 123840
attaaaattc tgagcgatat tgaacatatc aaaaagcgta gtggcatgta tattggctct 123900
tctgctaatg aaatgcatga gcgctttctg tttggtaaat gggaaagtgt tcagtatgta 123960
cctggtcttg ttaagcttat tgatgaaatt atcgataact cggtagatga aggtattcgt 124020
actaagttta aattcgcgaa taaaattaat gttactatca aaaacaatca agtaacagtt 124080
gaagataacg gtcgtggtat tccacaagcg atggttaaaa cacctactgg tgaagaaatt 124140
cctggtcctg ttgccgcctg gactattcca aaagcaggtg gtaacttcgg tgatgacaaa 124200
gaacgcgtca ctggtggtat gaacggtgtt ggttctagtt taactaacat tttttctgtg 124260
atgtttgtcg gtgaaactgg cgacggtcaa aataatattg tagttcgttg ttcaaatggc 124320
atggaaaata aatcatggga aactattcct ggaaaatgga aaggaactcg tgttactttc 124380
attcctgatt ttatgtcatt tgaaactagt gagctatctc aagtttatct tgacattacg 124440
ctagatcgtc tccagacact tgcagtagtt tatcctgata ttcaatttac ctttaatggt 124500
aaaaaggttc agggtaattt taagaaatac gcacgccaat atgatgagca tgctattgtt 124560
caagaacaag aaaattgttc tattgcggtt ggtcgttcac cggatggttt tcgtcaatta 124620
acgtacgtca ataacattca tactaagaat ggtggccatc acattgattg tgttatggat 124680
gatatttgtg aagaccttat tccacaaatc aaacgcaagt tcaaaattga tgtaactaaa 124740
gcacgtgtta aagaatgttt gactatcgtt atgtttgttc gtgatatgaa aaacatgcga 124800
tttgattctc aaactaaaga gcgtttgact tctccttttg gtgaaattcg tagtcatatt 124860
caacttgatg ctaaaaagat ttcacgtgct attttaagta atgaagcaat tttaatgcca 124920
attattgaag ctgccttggc tcgtaaattg gcggcagaaa aagcagcaga aactaaagca 124980
gctaaaaagg cttctaaagc taaggttcat aaacatatta aagcgaatct ttgcggtaaa 125040
gatgctgaca ctactctttt cttgactgag ggtgattctg ctatcggata tcttattgat 125100
gttcgtgata aagaacttca tggtggttat ccattgcgcg gtaaagttct taacagttgg 125160
ggcatgtcat atgctgatat gcttaaaaac aaagaactgt ttgatatttg cgcaatcact 125220
ggattagttc ttggtgaaaa ggctgaaaac ttgaattatc ataatattgc tattatgacc 125280
gatgctgatc acgatggtct aggaagcatt tatccttctc tgctcggatt ttttagtaat 125340
tggccagaac tgtttgaaca aggaagaatt cgcttcgtca aaactcctgt aatcatcgct 125400
caggtcggta aaaaacaaga atggttttat acagtcgctg aatatgagag tgccaaagat 125460
gctctaccta aacatagcat ccgttatatt aagggacttg gctctttgga aaaatctgaa 125520
tatcgtgaga tgattcaaaa cccagtatat gatgttgtta aacttcctga gaactggaaa 125580
gagctttttg aaatgctcat gggagataat gctgaccttc gtaaagaatg gatgagccaa 125640
tagtttactt taccacaagg atgtggtata attaattggg caaatgagga tattgaaatg 125700
aaatcatata aagtaaattt agaacttttt gataaagcag ttcatcgaga atatagaatc 125760
attcaacgct ttttcgatat gggagaagct gaagagttta aaaaccgctt taaggatatt 125820
agagataaaa ttcaatccga caccgcaact aaagatgaac tactagaagt tgctgaagtt 125880
attaaacgca atatgaatta atgaggaaat tatgattatc accactgaaa aagaaacaat 125940
tcttggtaat ggttctaaat caaaagcatt tagcatcaca gcatctccta aagtatttaa 126000
aattctgtca tctgacttgt atacaaacaa gattcgcgca gtagtccgtg aattgattac 126060
caacatgatt gatgcccatg ctctcaatgg aaatcctgaa aaatttatca ttcaagttcc 126120
aggacgatta gatccgcgat ttgtttgtcg agattttggt ccgggtatga gcgattttga 126180
tattcagggt gatgataatt ctcctgggtt gtataattca tactttagtt catctaaggc 126240
tgaatctaac gatttcattg gcggatttgg tttaggttct aaatctccgt ttagttatac 126300
tgatacattt agtattactt catatcataa aggcgaaatt cgtggttatg tagcttacat 126360
ggatggcgat ggtccacaaa ttaaacctac atttgtaaaa gaaatgggtc cagatgataa 126420
aactggtatt gaaatcgtag ttccagttga agaaaaagac tttagaaact ttgcttatga 126480
agtttcttat atcatgcgac cattcaaaga tttagctatc attaatggtc ttgaccgcga 126540
aattgattat tttccggatt ttgatgacta ttacggcgta aatccagaaa gatactggcc 126600
agatcgtggt ggattgtatg ctatctatgg tggtattgtt tatcctatcg atggtgttat 126660
tagagaccgt aactggttaa gcatccgtaa tgaagtgaat tacattaagt ttccaatggg 126720
ttcacttgat attgctccat cacgcgaagc tctttcacta gatgatcgta ctcgtaaaaa 126780
tattattgag cgtgttaaag agcttagtga gaaggcattc aatgaagatg taaaacgatt 126840
taaagaatct acatctcctc gtcatacata ccgtgaattg atgaagatgg gatattctgc 126900
tcgagattat atgattagta attcagtcaa atttacgact aaaaatctgt catataagaa 126960
gatgcaaagc atgtttgaac cagatagtaa gctatgcaat gcaggagttg tgtatgaagt 127020
aaatcttgac cctcgactga aacgcattaa gcaaagtcat gaaacttcag ccgttgcatc 127080
aagttatcgt ctgttcggta ttaatacaac aaaaattaat atcgttattg ataatattaa 127140
aaatcgcgtt aatattgtcc gtggattagc gcatgcgtta gatgataaag aatttaataa 127200
cactttgaat attcatcata atgagcgtct tttgtttatt aatccggaag tagaatcgca 127260
gattgattta ctccctgata ttatggcaat gtttgaaagt gatgaagtta acattcatta 127320
tttgtcagaa attgaagctt tagttaaaag ttatattcca aaggcagtaa aaagtacagc 127380
tcctcgtcct aaagctgcta ctgcgtttaa gtttgaaatt aaagacgggc gctgggaaaa 127440
agaggaactg tttacactta cgtcagaagc agatgaaatt actggttatg tagcatacat 127500
gcatcgttct gatattttct ctatggatgg cactacatcg ctttgtcatc catctacgag 127560
tattttgact cgtatggcta atcttattgg cattaatgaa ttttatgtta ttcgtccgct 127620
tttacagaaa aaggtaaaag aacttggtca gtgccaatgt atttttgaaa ctctgcgtga 127680
tttatatgta gatgcttttg atgctgtaga ttatgataag tatgtaggtt attcaagttc 127740
agctaaacga tatattgata aaattatcaa gtatcctgag ttagatttta tgatgaagta 127800
cttcagcgta gatgaagttt ctgaagaata tacacgactc gctaatatgg ttagttcatt 127860
acagggtgta tatttcaacg gtggaaaaga taccatcggt catgacatct ggacagtaac 127920
taatcttttt gatgtattat caaataatgc ttcaaaaaat agtgataaaa tggttgctga 127980
gtttaccaag aaattccgta ttgtttccga cttcatcgga tatcgcaatt ctttaagtga 128040
tgatgaagtt tcccaaatcg ctaaaactat gaaggccctt gcggcctaat aaggaaaatt 128100
atgtacaata ttaaatgcct gaccaaaaac gaacaagctg aaattgtcaa actgtattca 128160
agtggtaatt acacccaaca ggaattggct gattggcaag gtgtatcggt ggacacaatc 128220
cgtcgtgttt tgaaaaatgc tgaagaagct gagcgctcca aagttaccat tagcggtgac 128280
attacagtta cagttaagag tgatgcagct attgctccag ttgctaaatc tgacattatt 128340
tggaatgcat ctaaaaaatt catttcaatt accgttgacg gcgtaactta taacgcaact 128400
cctaatactc attcaaactt ccaagaaatt cttaatctgc ttgttgcaga taaattggaa 128460
gaagctgcgc aaaaaattaa cgttcgtcgc gctgttgaaa aatatatttc tggcgatgtt 128520
cgaattgaag gtggaagctt gttctatcaa aacattgaat tacggtctgg tttagttgat 128580
cgtattctcg attcgatgga aaaaggtgaa aactttgaat tttattttcc gttcctggaa 128640
aatctgctgg aaaacccaag ccaaaaagca gtatctcgac tctttgattt cttggtagca 128700
aatgatattg aaattacaga agatggttac ttctatgctt ggaaagtagt tcgcagcaat 128760
tactttgatt gtcactcaaa tacctttgat aacagccctg gtaaagtagt taaaatgcca 128820
cgtactcgcg tgaatgacga tgatacgcaa acttgttctc gtggtctgca tgtgtgttct 128880
aaatcttata ttcgtcactt tggcagttca accagccgag ttgtaaaagt taaagtgcat 128940
cctcgcgatg tagtatcaat tccgattgat tataacgacg ctaaaatgcg tacctgccaa 129000
tacgaagtag ttgaagacgt tactgaacaa tttaaataag ggcttcggcc cttaactaag 129060
gaaaattatg ttaggttatc aagcacgagt aaaagaagaa tacgatcaat taatgctcaa 129120
aattaatgca ctgagcaaat ttttagaaag tgaaaagttt tcaacggtta atgcagttga 129180
gcaagaactg ttgctttcgc agttcatctc aatgaaatct tacgcggatt gtttagagaa 129240
aagaattgca caatttaaat aaaataaggg gcttcggccc ttttgtttta aggaaaaatt 129300
atgatttatt gtatgaatat cggtgattcc gacataaaag agattaaact gcacggaaat 129360
catcacgcta atattgtgta ctgtaataaa tttgagtttg gtcacgaaaa acttggggtt 129420
ctttattgta atgatgttat aatcatggat aaaaaggaac tcgatgaact cgaccgtgag 129480
tctttagatg aaaatgatcg aatttattac ggcactctta aagtacataa cgcttatctt 129540
agtggtaaaa aggaaagtct aaatgcagaa aacgaatcca ggtttacaga gactatttca 129600
gattccgaca tttaccctat cgaacaatga tttgactagt gaaatgaagg tcaaaattgc 129660
tgatacagca agatactctt taaaacaaaa cccgaaccag gataaagcag aagtcattga 129720
aagatgtcgt atcgctgtgt atgcagagtt ttttgtagca gattggttga gcgggtatgt 129780
taacaaaggc caagaggatg ttaatgaccc gtatacatat gcatgggatg tattggcgca 129840
tccaagatat tgcgggcttc gtgtagaagt caaaacacac caaactgact cacgttggat 129900
ttctgtaaca acaggatgca gcggagagta tccatacggt tctggaataa atctagggcc 129960
cattctgaat catcaggtcg ctgactgtat aattatattc aacactaaag aaattcatcc 130020
aggtgtcatc cagtacactc cgaagttcat cggtgataga gaagaccttc gtaaggttgt 130080
aagaaaaagc aactacaacg gatggtatct ttccatttaa aaattttcac aaaacggttt 130140
acataccaca aggactgtgg tactatacaa ctatcaactg atacggattt ggagaacaaa 130200
atgtttacta cagctgaatt aaaacgagca aaagctaaga aagggcaagg aaaatataaa 130260
gctgaattag ttaaagaact tcagtttgct gaggctgaat tgaattcaat gattattcaa 130320
aatgctccag aaactgaaat tgctcttaag cgtattgcga ataagtgtct tcgtgatgca 130380
atcgtcgatc ttttagcgga ttattgagta aaatgaaatt taaattttat tacgctaaac 130440
ataaaataac tgatgagttt gtgtcagttg aatattctag cgatgatgaa ggtatgattt 130500
atactcgctt agggttatcg cactgggagt ctgatacgcc ttatttttca actcccgaag 130560
aaattacacg tttagttaat ggtcatatga atgaccactg gaatgtaatt ctttcagata 130620
gtcttaaagc ggctattaat agtaatgaaa tgaaaatcgc tgagattgaa ctatgagttc 130680
attatggtgg tgtttcgttt ggttaattag tattccattg atttgtttag catttacttt 130740
tgtgatgagg ttattatgaa aattttgaat tctgtactta ttgcttgtgc gtggtgggtt 130800
gcacaagttt cagcggtagt agttggtatt cacatttatt acgaatattt ttaaaaagtt 130860
gtttacaaga ctgttcctct gtggtactat acaactatca actacggagg aacagaaaat 130920
gaaaaagatt gttaaagcta tatggaatgt agttataata ctagtagttt tgagtatatt 130980
cccaatcgtt ttaatgattg atgtattaaa cgcttacttt ggatttatgt gaggaaaata 131040
tgaagcgtaa acgcagtgct tttacattta ttgaatggtt tttcgataat atttttccag 131100
ctttattcat tttcatgctg atttttgcct taggttcagt tgtagttgga atctatttga 131160
tggcagttgt cggaatggat attcaccaaa atggcttaaa atctgtggtt gaaacaattt 131220
ggaatggtgt aaaataatga atttactaag catttggttt tatattctta tgttttacat 131280
tggtgcaaat ttcccatatt ggatgggatg gtcaacaact gcatttggat tttatactcc 131340
ttgaggtgaa ttatgaaaat ctttaaagat gtaaaagttg gtgaaatttt ttgcttagat 131400
aatggtgatc agttaattcg tatttcgcct cttaaaagca ctagcgagaa aatgacagtt 131460
aacgctactt tagcaaataa cagcaatgaa cgtttctgta ttgaaaatga tactgaaact 131520
tatactgtag aagagttctg ggaattaagc gtcgactgcg acgattaatt tatcggccgt 131580
atgtattcat gcggccttgg agtagaaaat aatttagagg aaattaaaat gaaatatatg 131640
actgttactg atctgaataa tgcaggggca actgttattg gtacaatcaa gggcggtgaa 131700
tgggtttttg gaactccaca taaagacatt ttgtctaacc ctggatttta ctttttagtg 131760
agcaaatttg gtggtccatt tgatagtccg tgtgtatctg cgcgatttta tgtaggtaat 131820
cagcgctcta agcaagggtt cagtgcagtt ctaagtcata ttcgtcagcg tcggtctcag 131880
cttgcgcgta ctattgcaaa taacaatgtt ccatacacgg tattttattt gcctgcttct 131940
aagatgaaac ctctgacgac gggatttgga aaaggtcagt tagctttggc gtttacccgt 132000
aatcatcatt ctgagtatca aacacttgaa gaaatgaacc gtatgttggc tgataatttt 132060
aaatttgttt tgcaggcata ttaatgagca atttccataa cgaacatgtg atgcagttct 132120
atcgtaataa tcttaaaact aaaggcgtct tcggacgcca gtgaggaaaa tatgaatatt 132180
gcaaaattat taggagttat ttcatttatt tgttggatag tagcatgtgt tttaactatt 132240
tgtattgatg ccagcagcgt gttttcacaa gctttagctc agggtatgtg tgcatattta 132300
acatttgtgt tgttatctac taatgattaa gaaaatcttg ggctactcag tagcccttgc 132360
tgctttattg gtagcgctat attatggaat aatgttcggg ttaattcaag tcgtgctttt 132420
catttctgat gttattatgg cactacattc actagtatgg taaatttatg caactgaata 132480
atcgcgattt aaaaagtatc attgataatg aagcattggc ttatgctatg tacacggttg 132540
aaaatcgtgc tattccaaat atgattgatg gatttaagcc agttcaacga tttgttatcg 132600
ctcgagctct tgatttggca cggggaaata aagataagtt tcacaaactc gcttctattg 132660
caggtggtgt agctgacctt ggatatcatc atggcgaaaa ctccgcacaa gatgcggggg 132720
ctttgatggc taacacttgg aataataact ttcctttgtt agatggtcaa ggaaactttg 132780
gttctcgtac cgttcaaaaa gcagcagcaa gtcgttatat ttttgctcgt gtaagtaaaa 132840
atttctataa cgtatataaa gatactgaat atgctccggt acatcaagat aaagaacaca 132900
ttcctcctgc tttctatttg cctattattc ctactgttct tcttaatggt gtttccggta 132960
ttgcaactgg ttatgcaact tacattcttc ctcatagtgt ttcttctgtc aagaaagctg 133020
tactacaagc tcttcaagga aagaaagtaa ctaaaccgaa ggtagaattc ccagaatttc 133080
gtggtgaagt cgttgaaatt gatggccaat atgaaattcg tggaacgtac aagtttactt 133140
cacgaactca aatgaatatc actgagattc cgtataagta tgatcgtgaa acttacgtga 133200
gtaaaatctt agacccgctt gaagataaag gtttcattac atgggatgat gcttgcggtg 133260
agcatggttt tggctttaaa attaaattcc gtaaagaata ctctttgagc gataacgaag 133320
aagaacgcca tgcaaaaatc atgaaagact tcgggttgat tgagcgtcgt tctcagaata 133380
ttacagtcat taatgagaaa ggaaagctgc aagtttacga taacgtagtt gatttaatta 133440
aagacttcgt tgaagttcgt aaaacttatg tccaaaaacg aattgataat aaaattaaag 133500
aaactgagtc agcttttcgt ttagcctttg ccaaggcaca tttcattaag aaagtaattt 133560
caggtaaaat tgttgtacag ggtaaaactc gtaaagaact gaccgaagaa ctttcgaaaa 133620
tcgacatgta ttcttcttat gttgataaac tagttggaat gaatattttt catatgactt 133680
ccgatgaagc aaagaaactt gctgaagaag ctaaagccaa aaaagaagaa aacgaatatt 133740
ggaaaactac tgatgtagtt acagaataca ctaaagattt agaggaaatc aaatgagtcc 133800
attcattggt attacaagcg cggcattagt atctggtagc attttactgg cgggtttagg 133860
tgttgttcct gccatagcag gaggtcttct tgcgttcgga attcaacgtg ttatcatgac 133920
agttatcaca gtcatgcagt aattttaggg agagcctcgg ctctcccttt tttatttcaa 133980
aaattttttc acaaaacggt ttacaaccaa agcatactgt ggtactatac aactatcaac 134040
tactgataca gaattacgga gattagaaaa tgtctaaagt aacttacatc atcaaagctt 134100
ctaacgatgt tctgaatgaa aaaactgctg cgattttaat taccattgct aagaaagatt 134160
tcattacagc tgcagaagtt cgtgaggtgc atccagattt aggtaacgca gtagttaata 134220
gtaatattgg ggtattgatt aaaaaaggcc tggtggagaa atctggtgat ggattaatca 134280
ttactggtga agctcaggat attatttcaa atgcggcaac tttatatgca caggaaaatg 134340
ctcctgaact gctgaaaaaa cgagcaactc gtaaagctcg cgagattact tctgatatgg 134400
aagaagataa agacttcatg ttaaaacttt tagatgaaaa tggatttgtt cttaaaaagg 134460
ttgaaactta tcgtagtaac tatctcgcta ttttagaaaa acgcactcac ggaattcgca 134520
attttgaaat taacaacaat ggaaatatgc gaatttttgg atacaaaatg atggaacatc 134580
atattcagaa atttactgat atcggaatgt catgtaaaat cgctaaaaac ggtaatgtgt 134640
atcttgacat taaacgctcg gcagaaaaca ttgaagctgt aatcaccgta gcatctgaac 134700
tgtgaggaat aaataatgaa caagttagaa attgttaatg aacttcgtcg ttgtgcagaa 134760
cccactcaag aggggtggga catctggtac catggggctt atcttggaac tattgtaaag 134820
attaagactg gtaaatacat gattattcgt gaaagtaaag atgctccagt aggtattcgc 134880
aataatttta tggcagcgat aagttccttt acggatgcag cttacgaaat ttaccttgct 134940
gattataaag aatttcagga atctcaacca gttattcgct caattggcgt taacaaagct 135000
caacagaaaa ctttatggca gcgtattaaa ggatggttta aatgaaaact tttaaagaac 135060
gtttagctct gttagataaa gctttgtcac gtgagactcc agaaagtttg gctgctaaat 135120
tagcttctta cagtggtgaa tacacagaag aagatatttt aaaagaagtt cctgaaatct 135180
gttggcagac cgcatactgg gatgaaaatc aaaagtatca acgaagaatt gtttgcgcag 135240
ccaatcgttt taaattaaaa gatggacgaa ctcttgttat tccaggtgct cgtcattatt 135300
ctaaagatat ggccgaagtt ttagatgtag ttaaacccca attagttact cagcaagttt 135360
gtgatgatga ccaagggttt attgaccaat atagtaatta ttggacacgt gaagaagcaa 135420
tgattattgc aacttatgct ggacaagtac gtattgaacg tggtggtagt gaaaaagaac 135480
tttactctga ggacctttac taatgaatat taaaaagttt caaattgatg gaattatgaa 135540
tcaaattcag gcgctggaat atgccaataa aatgatgtca actaaatggg gaatttatgc 135600
caatgaacca gcatttcagt tctgtaatat ggaattcact aaaaagctcg taggaaaaga 135660
ttatgtatgc ccatttagtt ctccaataaa tggaatgtta aaacctgctt tacgcgatct 135720
ttatattgcg atgaatgaag agatgataaa agagctaaaa cgtcaactga aggtgattca 135780
atttggccag ggaaattaat tcaaaatccg attattttaa ttctctcaat gataaagata 135840
aaaatctaat acggcatttt attgttgaga tgggatatac tgacacacgt gatttaagag 135900
aacatatatt tgaatgtggt gtagctaaaa agttttcatt cacatgcaaa tgcttaagag 135960
aggtaattca gcactatgaa caatttagtc gcaaaacata attttaataa agcttctgtc 136020
cataaagata aaaagaaagc gtttaaagaa tctaatcgca aacagaaaca taaggggaag 136080
gtctatgatt attgattctc aatctgtggt tcaatataca atcaaaattg atattctaga 136140
aaagctatac aagtttctac caaatttata ccactcaatt gtcaatgaat tagttgaaga 136200
attacatctc gagaataatg atttcttggt tggaatttat aaagataact caaaggcggg 136260
atatttttac gtaattccag ctccaggaaa aagtattgat gatgtattaa aaactataat 136320
gttttatgtc catgattacg aaattgaaga ttatttcgaa tgagtcataa tcttgaaatg 136380
gtaatcgagc ataatgtagc tcaggaacgt aagtcgttca aggaattcgt agaaaaaatt 136440
tttgaagaaa ataacacaga ccagtttaca aatcaagcgt ctgatgatat tataataaag 136500
tcaactaatt gagtggtata gttaatgaat aaaaacattg atacagttcg tgaaattatt 136560
actgttgcgt ctattttgat taaattttcc agagaagata ttgttgagaa tcgtgctaat 136620
tttattgcat ttctgaatga gattggagta acgcatgaag gtagaaagtt aaatcagaat 136680
tcattccgta aaattgtttc tgaattaacc caagaagata agaaaaccct catcgacgaa 136740
ttcaacgagg gttttgaggg tgtatatcga tatctagaga tgtatacaaa caaataatta 136800
tttagccctt cctaatattc tggccgcctg agaacatatt gattcaaggc ggtcattact 136860
tatgtgatca tttctatacc agtacatagt tattgttcca gcatagatat tatccaaatt 136920
aaaatatgga caactataca tgtaatttat ttcgggagta ggctttttag ttggtaaaaa 136980
agcaaatttt gagttagaat aataatgacg tccatttaaa tgaactgcat attcatccat 137040
agttttatca acaggatatc ctccaagtga tttttcgctt attgttgaag gtaattttcc 137100
ttcatatgct atgatatcaa caaaatagtt taagttttta gggcggaaag aatacaccgc 137160
actaaagtct gcctcagatg atatatgaac tatctggagt tgttccaggg cgacagattc 137220
aaagcgtgca tttctttcct tttcaataat ttcactgtat gtttcatact ttgattgctt 137280
atagtactca aagaaactat ctcccctata ccaaacaatc gccatcataa ataaaagaat 137340
tacgacagct actcgggaag caagaacctt cccggtagcg ttatctttga acaagcgatc 137400
tagaacacca aacagaatac cagagggcga aaatgatatt ctaggtgctg ccatattacc 137460
tccaatttat caatatttat aactgagagg tattatcgtt taaatccagg agccgtagat 137520
cgtgcctgta gcgccccatg atggtgaaga accgaatact gccctgcctg gagcaccacc 137580
gccagatcta gataagtgat taccccatcc atctccgccc cgacctccag catcaccgcc 137640
attgcctccg ccgaattggg aagtgtaacc ggcaccgccc ggggcgtcat aactagcatt 137700
accaccaggc caattaacgc cgcctccgcc gatgccaaat ggtctaccac caccgccacc 137760
tgctgtagca tttggcgccc agctattctg taatgacact gcaccaccac caccgccgcc 137820
tgatgcaata acgccatagt tccaaatacg aagtcttccg ccaatatcat tttggattac 137880
atcgccgcca tttgtgcctg ggtttccgtt tacagtaccg ttaccacctc gtccccacat 137940
atgaactcca ccatgaatat tcaaagtaac atattcattt ggcgtatcgc catacataaa 138000
gaataatgga acatctttac tatatgatac caaatttccg gtgatattaa acactatagg 138060
tgcactacct gcctcaaaac atctatctcg gaaccattga ccattgaagt tatggtctgc 138120
tccaagcgtg tgaattactt caacagatcg acctatcata ttactcatcc aaaatggaac 138180
acccattctt aatcttacgg ctgctcctgc catccaaggg tctccagtct gtacccttgc 138240
agaccatcct acccacggtc cttcaactgc catataacct ccaaggggcc gaagcccctc 138300
ttattatttt aacaatgatt taactaattt tttaagctct tcaatctctg acttaagtcc 138360
tgcaatttct gcagtatgct cattgattgc agctgtattt aaaccaatta caccgttata 138420
gttcaaacga agtaaagctt caccattagg gtcaccttca accaattcag gtaaaatagc 138480
ttgaacttct tgggcaatta aaccagcgtt aggttcccat ttctgattgc cttcttcatc 138540
taggcctcgc ttctgcatat aagtgtaacc gttaatttta gaaagcttct cagaagcatt 138600
ttcaaattta acaaggtctt ttttaacgcg aatatcagaa cggacataaa catcacggac 138660
atatgtagaa tagttgtcat tcgcctgaac gagatgacca taagacataa tagctcttcc 138720
ttgctcagtc cacaaagcgc cagtggtatc ccaaagacct tcatggatat gataagagct 138780
agaccatgaa gcaatatgca tgccattggc aaccatattt attcggccgt caccacccca 138840
tactaagcca gtgtcattat caccaataac aacacatgcg cctgtccatg caggatcacc 138900
tccaccagct gatattctta ctccagcttt aaccatgtca ggaacgtaca tgtttccatt 138960
atggtggaat tcgaagatag cttgcggatc gctagcattt tcctggttac caacacgaat 139020
aatagcctga gcccattggt tagtgatacg gcgcatacca aaatctacgc ctgatacgta 139080
tccttcgtta gtaataccag attttccttt aataatagga taataggagt cattgctgac 139140
ggatccaaaa tctacaaata caggcgcttc taaaccccat tggtcacccc aggcgccaga 139200
tttatgcgca acccattgtg cagcctttat ataaagtcgg tccctattaa aataaaaagt 139260
atccgaccct tgaggagcta aaccaacttc tccgctatta tgaatactaa cgcctgaatt 139320
agtttggaaa ctataaaacg ataaggtgtt ctcagtgccg ccattaccaa cataccagtt 139380
attaacgcct gctttttgtc ctttcacata acaagattcg gttgcagcac tgttaataac 139440
aatagcatcc gagtttgcat tcagagttaa acggcctgtc atcgtgtcgc cttctttagc 139500
cacacgggag gcaatggcat cgcgaatatt agttacgtcg cctgctgaag taaacgtttt 139560
ccagatatca gaccagatat taccattgcg agcaatagta gcttcaccac caccgacaga 139620
aacgttatct gggaagttaa cagtaccgtc ttgattaaaa cgagatgtat ggccttgtga 139680
accatcttct ttgatatggt gtaaaacaaa tgtacccgaa ttaatttcag tacctaaaga 139740
ccaaacagct ttactgttta aaaacttctg tttaacaata ggataatatt tacttactgc 139800
gtcatcatcg atttcctgga aaataggagc tgcttgaaca tattgaatat cataaccacc 139860
agcgcccgcg ccgtgaccag taaatttaat ataaccgtta gcagcaaacg tattgtaact 139920
tgattgtaaa tctggaatag taactttacc agtatctaaa gccatactaa acgggcgaag 139980
tggaccgata tcaccatgtt taccttcacc ataagcagtt ggaataatat gaagactacc 140040
ttctgaacgt ctaaaaatag ctccataatc tgcgttccaa atacgaagcg cattcacagc 140100
cccagatgaa atttcgcctg ttgtgtgaac tcctttattt ccagcagtaa caccggatga 140160
ttcaaatgaa ccattgacgt tcatttctac ttcgccggta gtaagtcttt gaatatagct 140220
catccaacta gttgcgtcag aaatttccat gacattttta cgggtgcctt cactaggatt 140280
agtaaaggta ttaccccata cagaaattgt catattatca actgaactgt taccagttgt 140340
gttacctcta aacatcagcg tagaagaatt attacgacca tcaatattaa ctgaaccacc 140400
aataacgtca atattaccag gagtaactag caaaccgcca tgagtattaa tgtttgtggt 140460
acccttaccg cggaaataat gatgataatt accaccttgg taatatccta aaagagtctg 140520
accatctcca aacgcattat tatcatggta agtaacaaca gtagcgagag catagttttc 140580
agtaggagga gtagttaaat cattgccatt tacagaataa cccataacca tttttctaag 140640
gcttacggtt gattcaggac tataaaggaa agttctcgta ccattgttta ctacatagaa 140700
ataaccatct tgataccatt ttaatccggt atcattatca cccaaagcaa tagaaccttt 140760
acctaaggct gaatacgtca taggccctgc tgattccata cctactgcaa tcgaatgccc 140820
agcttgaaaa ccacctgaat aagcaaaaga caacatgaaa tcagtagggg ttgaaccaga 140880
ataccaactg atgccgttat tttcacaaat ttcatggagc attgcggccg ctgggttggt 140940
acgtacaacg cgcaaatagt ttttatctgt gtcagaatta ttattggcca ttgaatagat 141000
atcataatcg ccgacaactt taccatttgt aataacttta ttagtataaa ttacgggagt 141060
tgatacagat ttccacccaa aaacttctgg tgaagaaaac aaaccatttc cattaaaagc 141120
gaaagtgctt tctgaactag ctttgtaatc ttgaactctg atgttaacta cttgtgtagt 141180
taaaccgtca ttagcaggag aaaaaataat accgcgttca cggtcggcgg aatcatgaaa 141240
acgaacatgt gctgtacctg aactttttgt aataagttct ccgccttcag tcataatctg 141300
cccggcggca ataatatcgc gagttactcg agcaatacca gttaaattaa aattaccagt 141360
ctgagtgaag gttccattta aagtataatc accagtttga ttataatttc ctatatgaat 141420
aacattcccg tcaatgctac cgcctttagc aaaacccaga tcaatgatat ttccttggtc 141480
atctttagta aaaagtacgc ggtcttttaa atttatagcc aattcacctt cggctaatac 141540
tgaagcggca ggacgtgctc ctgcagtttt gcttctttta aattgtattt gttttaaagt 141600
agccataagt cctcttaata atagccgaaa tcttgaacag aatccttaat aacaatttga 141660
tcaaatcgtg gaacatgcga aggttgagat gcaggattct gtgaaaaaag gtttggcgca 141720
gttaaattac ctgtcatagt atctccagag cgtaatactc tagagtttgc gtttgctgta 141780
acaatattta ttgctccatc gacataatct ttgcgagtta agtgtgctgg gccggtcggt 141840
actgaagcat tagaaataac ttgttggcca gaaacaatat tgccaactgt ttcaacttta 141900
ccactcctgg cattaaacca gattgtgcgt ccctggatcc catcacttgt gcatgtgttc 141960
caaataccaa tgccgtacca tgaacgtaaa tccatgttag ctttttctct ggaagctcca 142020
tctccattgc cagaatataa cccattcagg tctgaaccgc cagaaaacgt tgcagaaatc 142080
ctaacgcctt ctttaaattc tacttctttt tggaaacctt gagactttgt gccaccatta 142140
gctttagaaa cgaaatcgtt atcagttgcc tgtggtttat tgtattctga atatatttta 142200
aatgatttat agagtacatc gtcaccggct ggattcaatg gaaaatttcc ttgatgccaa 142260
atgacagagc ctccagttgt tgaacctact tttaaatcag ccattgtatg cccctttatt 142320
ttaatagtat ttataaagaa aaagggaacc cgaaggctcc ctcaatttat acttctctaa 142380
attcttgccc aaatacttta ccagctttag acgatgcttg cgtaggaagt accattatat 142440
ccggaggtga agcagattca cagatataat taactcgaat accattgacg ccaaattcag 142500
caggttttga aattccgcca tttcttgaca cttccgaaaa gcttaaattc ctcatgccac 142560
cttgaccagc ttgtgcagtc ctttgcgcgt atatcgtaaa tcctactgca ttttctggaa 142620
taactacata atcttccttt aattcccatg acccagcttg tccagtaaac tcagcatgtg 142680
ttgaagaaat atatccattc gattcatcat aaaaacggat agatatattt gtagttccaa 142740
gcgcaagtaa atcggcatca gcatatagct gtgctttaag ataaagaaca tcgccaggaa 142800
ttaaattata atcagagagt ttacttatcg cggatgaagt tggtaaacgt gcaatttcgt 142860
tattagttcc accaaccgct gacataaatt gctcaacgct ttcgtatgtt cttttaggaa 142920
atcctgtagc tccaacgtct tctaaactat caaatacaac atctaaaata gtttgatagt 142980
catctgtgct ttttctatta cttagtttaa catgctctaa tgcaatagct cttttagaag 143040
aagtgtaaaa agcagcatat gatacgtcga atcttgacaa tacagaatca gatggaaaag 143100
cagacgttcc tgcggttctt atccaagata ctacttcagg aggaaaatta acttttccgt 143160
tagttaatat agcaacaagt ctattattcg tcaaagaatt catgaaacta acaaaagcag 143220
ctgatgtagt atcatttgaa gtcgaaaaag catatgactt actatcaact aatgctcctg 143280
tagaagggtc aaaaactctt aaatgaagtc ctgcgctaaa tgtttgactt ccgacaggat 143340
tatcctgaaa tttaacgtat ggtccttctg cagtagaaag cgggcaagaa cccgctatac 143400
ttattttata tcttactgaa ttgctttccg ataaaaatgg cgtttggaca tatccttgtc 143460
caaactctgc cataaatttt tccataatac ctcttattca atccattcaa atttaacaga 143520
tttattcact gggtcaggaa taatgcgaac attaccaatt cgtaagaaat cacgaatagt 143580
aagattcccc attgtagcat tatcagatgg taaagcaccg atatcagatg gctgaggagg 143640
gttaccccca tcaaatacct gaacaaaact tgaccaagag tttttggttt tctgccatgt 143700
acgcgtccag cgagtggtgc gcgcttctgg ggtcgttgga taagtaatcc aatcttggta 143760
aagcgaatcg agtgtgttac caaactgagt caatgtacca ggagatttaa cctcttcgcc 143820
acgttctaag tatggaagtc cagtcacttc attagttttt tcaaccattt caaaataacc 143880
cgggaactgg ttataagtgg ctgaatcatt aatatcgatt gaccagaatc ctacagtatc 143940
agatgttggc gcacgggtat ataaatcaga ggttttagta ccctgagaac gaattctcga 144000
gttaacagtt aaaccacctg aacttatagt agcacctttg gcaatgatta agctttcacc 144060
aatcgttact tgaccagatt gattattaat tgataatgga cgtaatccat taaatccacc 144120
gctctgatca ccggctgcag tgagcataaa ataggtgtca ttaccagcgt tacgaataaa 144180
gaatccataa ttaccattta ttgctctgaa agcattcgat gatttactga taaattcgcc 144240
attagcagta actgaactac cgaatgttgc aacgccattc gcattcaaag aacctaaagc 144300
attcacattt attggcatta cagtaccatt aatgctaaat gctatattac catctttatc 144360
gcgttgagaa taaaagtgat aagatgtttc atcactaact tcaaatacgg tagaacgtgt 144420
tgtgtttgat tccccactaa attgattccc ccacacgctg actgtcatcg tttgagccgg 144480
gttcgttcca gtttgaggtc ctttctcaaa aatcagacga gttgctgttc catcagtatt 144540
agaaatggtt agtgtactat ttgctgaaac tggtccaccg aacgtagcag tactagatga 144600
tacaagaggg gcactcagat tcgtttgttg cgttaaggtt agtgaaccat taactgtctg 144660
tgcaatatcc ctacgaatga actgagatga atctagacca tctaataaat tactatctgc 144720
agcttttgct tttaacggca aataatttgc taatacgcgg tttaattcat atggcgatac 144780
tgcatagcta tttttctcat ataattctaa tgactgtgtt gaaccaacta tatcattacc 144840
aacgaatgta attgaaccag atgaagtttt aacaaaacct cttaccaaag tagtagctgc 144900
ccaagtaggt tcactctgta caacccattt taaatttttt ggagatacag cagtatttgc 144960
tgacgttcca gctacagttt cagcctgagt tgcaacttta ataacgcctt cttgcgattc 145020
ggtagattta gtacctaaaa gctttttagg agttattaga acattatcca atgttcctgc 145080
agcagcttca acttgtgtag ctacacgaag tgtaccacgt tgtgtctcat ttgcttcaag 145140
aatattaagg gtataatggt cccagagagt tcctgattca actaatccag atagagcaac 145200
aacagaagta cgatcagtac tattaaatct ggttttaatt tttaatggtg tagagatacg 145260
agtatcgtcg acgcctgcgt cgaattcaac ttgcgtagca atttcagcta taccacttaa 145320
accttcagtt gctttacgat catttaaagt tttaggagtg actgcacgag tataatcagt 145380
tcctgtatta acttcacttt gcgtagcaat ttcaattaaa ccaattcttc catcagttga 145440
tgtcttttta tgtaacgttt ctggcgttac aaccgcattt gcccatcctt cttgactctg 145500
tccagcaatt acttcacttt caactgctaa aattactgca ccttgttgtg ttggagtagc 145560
tttatactga tctaaagctt taggcgaaac aactaaatta ttagtgtttt tattgtaaac 145620
atttgtacca tttaattcac ggctagaagc tggagtagct cctgcggtag atacaaaagt 145680
tacgatacca gataatgatt cagaaccttg acgagcttga agctttttag gagtgatgat 145740
tgtagtatca tcggttcctg tattagtttc ttgctgcgta gcaatttctg cgacacctct 145800
gcgagtttca gtagcagttc tttcattcag ctttttagga gtgatgataa tatcatcagc 145860
aaaagagaat gtagtgtcct ggttcacttg ggcagtagtt gctattcttg cgatacctct 145920
acgagtttct gtagcagtac ggttagctaa tgtttctggt gtaattgcta attctttctg 145980
tggagaattt tctaaatcag catttgcttg agcttgtgta gctaaagcaa ttacgcctaa 146040
tcttgctcta gtagaatcat ttaaagaatc aactctttca actgttggaa cgttttgttg 146100
tacaacccag tattttccgt cagaatcttc gatataagca agttgtaaaa ctggaacata 146160
attagtttca ccgttaaaaa ctaattcttg aacagtcacc cattcagctt caggcggata 146220
ctctgaacgt tttgggaatt gcagcaattg aactgaagaa gcaattttat cttcaccggc 146280
ggctttgatt ttaactgttt gtccttttct catgtaattc atggaaattt taacagtatc 146340
accaacagaa atattagttg gaagctgaag ttcaattgtt tgagttgttc cgttattcgc 146400
accaaatacc ataacttctt catttggacg aatactagaa ttagttgtta taatacgtaa 146460
acgtgcttta ctatccccgt caaacaatct ccacaatttt tcattatcat catacatcaa 146520
gaaaccgtca atcgatgtac gtccttcaat agaatgagtt ccatcttctt gtattgaagt 146580
agtttcatcg tatgtagtaa caattgtatg ataaagtgga tttagtttat ctaaatcgac 146640
gaaattaata atatcgccat gattagcaaa tctcggaagt ttaatattaa tcggcgcagc 146700
ggaagtaaat ctacgcacga taaaatcgtt agattgcgcc tgataaagac ttgccggtgt 146760
tacaattgca gcttctctgc tataatcagc aacgtacatt tgccacagac gattactaaa 146820
aattaaaact atctgtgatt ttggatgagt cattagtact gatcgtactt gctgacctct 146880
aaaatttaca atgctttgca ccggagctgt aattaaaact tggttaactc caggttttcc 146940
tccaatgtct tggagaacga tagtatctcc atcaattggg gaagatggta aagtaaatgt 147000
aatgtcatta ccagctgcag tatcaactga aattgattcg cctgacttta attgataagg 147060
tcctgatgaa acagttgtcc aattagcatc agtacgtaat gatctccaac gtacgctatt 147120
aaaagctcct gctggttttg gaatatcatt tatagcagcc caaaagcggt tatcataaat 147180
gattacaaaa tcttttaaat atccacgagt tggatcatat tgttgaactg tgttttcttg 147240
aattaagtaa tcaacgttga caccgtcagt tcctacggta cgatcagcta aagctacgtt 147300
gattatttta tcgccacctg cgtccagacc gtcttctgct ctgaactttc ttttaatctc 147360
ggccattctc ccgggctcct aatgtgtttt caataataag tatttatact tgtttacttt 147420
aagatttgga tagtatataa tagaaatctc actaattgaa cgaggttcat atggatttag 147480
aaatgatgct ggatgaagat tacaaagaag gaatttgctt aattgacttt agtcaaattg 147540
cgctttcaac tgctttggta aactttccag ataaagaaaa aattaattta tcaatggttc 147600
gtcatttgat attgaactca attaagttta atgtcaaaaa agcaaaaact cttggataca 147660
ctaaaattgt actgtgtatt gataacgcga aatctggata ctggcgtcgt gattttgctt 147720
attattataa gaaaaaccgt ggaaaagcac gagaagaatc tacttgggat tgggaaggtt 147780
attttgaatc cagtcataaa gttatagatg aactgaaagc ttatatgcca tacatcgtta 147840
tggatattga taagtatgaa gcagatgacc atattgctat tcttgttaaa aagttctctt 147900
tagaaggaca taagatttta atcatttcat cggatggtga ctttactcaa cttcataaat 147960
acccaaatgt taagcaatgg tcaccgatgc acaagaaatg ggttaaaatt aaaagcggtt 148020
ctgctgaaat tgactgtatg actaaaatcc ttaaaggtga caaaaaggat aacgttgctt 148080
cagttaaagt acgatctgac ttttggttta ctagagttga aggtgaacga actccttcaa 148140
tgaaaacctc tattgttgaa gctattgcta atgaccgtga gcaagctaag gtgcttctta 148200
ccgaatctga atataatcgt tataaagaaa atttagttct aattgatttt gattatattc 148260
ctgataatat tgcttcaaac attgtgaatt actataattc atataaatta ccaccgcgtg 148320
gcaaaattta ttcatatttt gtaaaagcgg gtctttctaa attaactaat agcattaatg 148380
aattttgagg tgaataatgg ctaaaaaaga aatggttgaa tttgatgaag ctatccatgg 148440
cgaagatttg gctaaattta ttaaagaagc atctgatcat aaactgaaaa tttctggtta 148500
taatgaattg attaaagata ttcgaattcg tgccaaagat gaacttggcg ttgatggtaa 148560
gatgtttaat cgtctgttag ctttgtatca taaagataac cgtgatgtgt ttgaagctga 148620
aactgaagag gtagttgaac tttatgacac agttttctct aaatgatatt cgtccggtcg 148680
atgagaccgg tctttcagaa aaagaacttt caattaagaa agaaaaagat gaaattgcaa 148740
agcttcttga ccgtcaagaa aatggattta ttattgaaaa aatggtagaa gagtttggaa 148800
tgagttatct tgaagctaca acagcattct tggaagaaaa ttctattcct gaaactcaat 148860
ttgctaaatt tattccttcg ggtataattg aaaaaattca gtcagaagct attgacgaaa 148920
atcttttacg tccttctgtt gttcgttgtg aaaaaactaa tacattagat tttctactat 148980
gattaaactc cgcatgcctg ctggtggtga aagatatatt gatggtaaat cagtttataa 149040
attatactta atgataaaac aacatatgaa tggaaagtat gatgtaatta agtataattg 149100
gtgcatgcgg gtgtctgatg ccgcttatca aaagcgaagg gataagtatt ttttccagaa 149160
gttatcagaa aaatataaat taaaggaact tgctttaatc tttataagca atcttgttgc 149220
taaccaggat gcttggattg gtgacatctc tgacgctgat gcacttgtgt tttatcgtga 149280
atatatcgga cgcttaaagc aaattaaatt taagtttgaa gaagatattc gcaatattta 149340
ctatttcagt aaaaaagttg aagtttctgc ttttaaagaa atttttgaat ataatccaaa 149400
agttcaatca agttatattt ttaaactact tcaatcgaat ataatttcgt ttgagacgtt 149460
tatcttgctt gattcgtttt taaatataat cgataaacat gatgaacaga ctgataattt 149520
agtctggaat aattattcta taaagttaaa ggcttataga aaaattttaa atattgattc 149580
acagaaagct aaaagtgttt tcattgaaac tgtgaaatct tgtaagtatt gatatgaata 149640
tagtatattg gtttacattt gaagaccgtg tcaaaaataa gactccgccg tactactata 149700
tcggcagtaa attaaattgc tcatttgaga atggaataat atatgactct tccggaaagg 149760
aatactggag ttcgtgtaaa caaaaaagat ttttaaatgc ggtaatgctt caaaaaccga 149820
gcgttaaaat aattcaaatt gatgatgatt tggatgttat tgaagcagag cgaaaatacc 149880
aacttgaagt aaatgccaga gataatccag actattttaa tctggtatat gctggcggcg 149940
ggtttggtgt gagtggtgaa actcatccag ccaaagaccc ggaagttaga gagcatatga 150000
gattggctaa ttatatgaac cgtgacgatt ttagaccttg gaaaacatca cgagctaata 150060
tagagtcttg gaaattatct catattgctt acgagaatta tgtgttatta ttatcctcta 150120
atctgtacgg taaaactcct ggatggcgaa gagttaaagg taatataaat ataactgatg 150180
caactgctaa atcgatggta aagtatttca actcaggttg gatacctctc gaagacccag 150240
agtattgcga attatgccag ctatgaggta aagtgtcata gcaccaactg ttaattaaat 150300
taaaaaggaa ataaaaatgt ttaaacgtaa atctactgct gaactcgctg cacaaatggc 150360
taaactggct ggaaataaag gtggtttttc ttctgaagat aaaggcgagt ggaaactgaa 150420
actcgacaat gcgggtaacg gtcaagcagt aattcgtttt cttccgtcta aaaatgatga 150480
acaagcacca ttcgcacttc ttgtaaatca cggtttcaag aaaaatggta aatggtatat 150540
cgaaacatgc tcatctacct acggtgatta cgattcttgt ccagtatgtc agtacatcag 150600
taaaaatgat ttgtataaca ctgacaataa agagtacggt cttgttaaac gtaaaacttc 150660
ttactgggct aacattcttg ttgtaaaaga cccagctgct ccagaaaatg aaggtaaagt 150720
atttaaatac cgtttcggta agaaaatctg ggataaaatc aatgcaatga ttgcagttga 150780
tgttgaaatg ggtgaaactc cggttgatgt aacttgtccg tgggaaggtg ctaactttgt 150840
actgaaagtt aaacaagttt ctggttttag taactacgat gaatctaaat tcctgaatca 150900
atctgcgatt ccaaacattg acgatgaatc tttccagaaa gaactgttcg aacaaatggt 150960
tgacctttct gaaatgactt ctaaagataa attcaaatcg tttgaagaac tgagcactaa 151020
gttcagtcaa gttatgggaa ctgctgctat gggtggtgcc gcagcaactg ccgctaagaa 151080
agctgataaa gttgctgatg atttggatgc attcaatgtt gatgacttca aaacaaaaac 151140
tgaagatgat tttatgagct caagctctgg cagttcatct agtgctgatg acacggacct 151200
ggatgacctt ttgaatgacc tttaacagat tatattacta attaattggg gaccctagag 151260
gtcccctttt tttatttcaa aaattttttc acaaagctgt ttacatcctt gtccttccat 151320
ggtactatac aactatcggc aatactgctg atgattaaag aggaaaataa tatggctaaa 151380
gttgatattg acatcgttga ttttgaatat attgaagaga ttattcgtaa tcgttatcct 151440
gaacttagta tcacaagcgt gcaagattct aagttttgga gtattcaaat cgttattaaa 151500
ggtcctcttg aagacctcac cctctttatg gctaatgaat attgtgatga catgggttct 151560
gaagacgcag aattttacat gggattgatt gaacaataat tatcaagggg ctatcaagcc 151620
cctattaaaa tgaggaaaat caaaaatgga aatcggcaaa aaatatgagt taaatccaca 151680
ccgtattaaa tctttcattg atattagttc atcaaatgct agtatggtcg gcatcattca 151740
agaaaatggc ggttggtttg aagttaaatc aatatcaagt ttagatggat ttgattatgt 151800
aaccgaaatc atttgcgcca atggtgaaat ctataatgat gatggtatgg gtgatgatta 151860
ttttgaactt agtgaagaag agttttattg ttttcgcgag tataaagaac caacttttga 151920
agaagatgaa gtcgaagaca ggatttctgg cgtaacaaaa attcactgca ttgtagatga 151980
aaacaatgta gatgaaatca ttgaactttt gcgaaaaact ttcaaaaagt agtttacaga 152040
agggtagtag cgtgatacta ttaccctatc aattaaggag aataaaatga gattacaacg 152100
ccagagcatc aaagattcag aagttagagg taaatggtat tttaatatca tcggtaaaga 152160
ttctgaactt gttgaaaaag ctgaacatct tttacgtgat atgggatggg aagatgaatg 152220
cgatggatgt cctctttatg aagacggaga aagcgcagga ttctggattt accattctga 152280
cgtcgagcag tttaaagctg attggaaaat tgtgaaaaag tctgtttaag gaaaataata 152340
tgatttttgt atttgaattt atgaatgatg aattcgatta tgcaattttt aacgcattgc 152400
ataatcctga tttaagtgaa tttaatgaaa tgttttctga cgctttgagt atgtcagaag 152460
aatactgtgg agaatgtcaa cgtgtttgtg tgacagtttt tgaaaacaaa gaaaagacat 152520
atgaagaatt attctttgac gctaataaag ccactgaatg gtttattgaa aggggctttg 152580
cgtaatgatt aaattggtat tcgcttattc tccaactaaa accgttgaag gctttaatga 152640
attagcattc ggtttaggtg atggtttacc atggggacga gttaaaaagg acctccagaa 152700
ttttaaagct cgtactgaag gtacaattat gattatgggt gctaaaacgt tccagtcatt 152760
atctacatta cttcctggac gtagccatat tgtggtgtgt gaccttgcgc gtgattatcc 152820
tgtaactaaa gacggcgatt tagcacattt ctatattact tgggaacagt atataactta 152880
catttctggc ggtgaaattc aagtgtcaag ccctaatgca ccattcgagg ctatgcttga 152940
ccagaattct aaagtaagtg taattggcgg acccgctctg ttatatgctg cattacctta 153000
tgcagatgaa gtagttgttt ctcgtattgt taaaaggcat cgtgttaatt caactgttca 153060
attagatgca agttttcttg atgatataag caagcgtgaa atggttgaaa cgcattggta 153120
taaaatagat gaagtaacaa cccttacgga atcagtatat aaatgaaata acgcgtggca 153180
gaaaatatga attttaatta ttaccctatt ttattagaaa aagacgcgaa acagccaaag 153240
tggcagggtc ctcagtttat taaaggtgtc tatcaattag tagttcctaa agacaagatt 153300
tatagcagtt gtttcactga atccgcttgc agtattttcg gtaatagttc tccgtattgg 153360
aattttgaca taaagctgga tagaaatatc gatatttggt tgaaagctat ggatattggt 153420
aatatcacgt ttgatgagaa taattatcat attattggtc gcttttccaa acgcggtaaa 153480
gaattatatt tcacgcctga aattgagaga aaatttgatg ctaaaccgta ttgattattt 153540
agcttcataa aatgtattat aatttatata aggtactaaa tgaaacaata ccaagattta 153600
attaaagaca tttttgaaaa tggctatgaa accgatgacc gaacaggcac aggaacaatt 153660
gctttgttcg gtactaaatt gcgctgggat ttaaccaaag gttttcctgc agtaacaact 153720
aaaaagctcg cctggaatgc atgcattgct gagctaatat ggtttttatc aggaagcaca 153780
aatgtcaatg atttgcgatt aattcaacat gattcattaa ttcaaggcaa aacagtctgg 153840
gatgaaaatt acgaaaatca agcaaaagat ttaggatacc atagcggtga acttggtcca 153900
atttatggaa aacagtggcg tgattttggc ggtgtagacc aaattataga agttattgat 153960
cgtattaaaa aactgccaaa tgataggcgt caaattgttt ctgcatggaa tccagctgaa 154020
ctcaagcaga tggcattacc gccttgtcat atgttctatc aatttaatgt gcgtaatggc 154080
tatttggatt tacagtggta tcaaagaagt gttgacgtgt tcttgggctt gccattcaac 154140
attgcatcat atgctgcgtt agttcatatt gtagctaaga tgtgtaatct tattccggga 154200
gatttgatat tttccggtgg taatactcat atctatatga atcacgtaga acaatgtaaa 154260
gaaattttac gtcgtgaacc tatggattta tgcgaattgc aattaaaatt tccagatgaa 154320
tttgatgaat gggacacaga atcgcaggta ttttggttga gtcaattcgc aaagccgcat 154380
aattttgttc ttaacaacta tgaatcacac cctcctatta aaggaaagat ggcggtgtaa 154440
ttttaattta attgcgagga tatatgattt tacgatttaa agatacttct ggtgtagttc 154500
tttttacact tcctaatcca agtgagttag aagttccagg accaaatcag cctattatca 154560
tttatggcaa aaaatattat actcataaaa tgactcgtga gtattttgat aataaaattt 154620
ctacagttaa aacttcttct gactgttact acgatattac tgttttaacg gaagaacaat 154680
atgaacacct acaaccgcgc gggccgtcta tgccgggtag tgaataaata taaatccgac 154740
tttgatgtta atattcaccg tggtacattt tgggggaatt acgtcggtaa agatgctggc 154800
agccgggagg ctgccattga attattcaaa aaagatttta tacgtcgaat taaatccgga 154860
gaaataacta aagcacattt agagccttta cgtggaatga ggctaggatg cacatgtaaa 154920
ccaaagccgt gtcatggtga tataatagct catatagtta accgattgtt taaagacgat 154980
tttcaagttg aggacttatg caattaatta atgttatcaa aagtagtggt gtttctcaga 155040
gctttgaccc acaaaaaatt attaaagttt tatcttgggc agctgaagga acatcagtag 155100
atccttatga attatatgaa aatattaaat cttatctccg tgatggaatg acaactgatg 155160
atattcagac tattgtcatt aaggctgctg cgaattctat ttcggttgaa gagcctgatt 155220
atcaatatgt agctgcacgc tgtttaatgt ttgctcttcg taagcatgtt tatgggcagt 155280
atgaaccacg ttcatttatt gaccatattt cttattgtgt aaatgaaggt aaatatgacc 155340
ctggattatt gtcaaaatat tcagcagaag aaattacatt tttagaatca aaaattaagc 155400
acgaacggga tatggaattt acttattccg gggcgatgca attaaaagaa aaatatctag 155460
ttaaagataa aaccactggt caaatttatg aaactccaca gtttgcattt atgactattg 155520
gaatggcact gcatcaagat gaacctgttg acagattaaa acatgttatt cgtttttatg 155580
aagcagtatc tactcgacag atttcattgc caactcctat tatggctggt tgtcgtactc 155640
caactcggca gtttagttca tgcgttgtta ttgaggcagg tgattcgctg aagtctatca 155700
ataaggcttc cgcttcaatt gttgagtata tttctaaacg cgctggaatt ggtattaacg 155760
ttggtatgat tcgtgccgaa ggttctaaga ttggcacagg tgaagtgcgt catactggtg 155820
ttattccttt ttggaaacat tttcagactg ctgttaaatc atgctcacag ggtggaattc 155880
gtggcggcgc tgctactgct tattatccta tttggcattt ggaagttgaa aatcttctcg 155940
ttttgaaaaa taacaaaggt gtagaagaaa accgtatccg tcatatggat tatggcgttc 156000
aactgaatga tttgatgatg gaacgttttg gaaagaacga ctacattact ttgttcagtc 156060
cacacgaaat gggtggcgag ctttattatt cttattttaa agaccaagac cgtttccgtg 156120
aattgtatga agccgcagaa aaagacccta atattcgcaa aaagcgtatt aaagcacgtg 156180
aactgtttga attgctcatg actgaacgat caggaacagc aaggatttat gtacagttca 156240
ttgataatac gaataactat actccattta ttcgtgaaaa ggcacctatt cgtcagagta 156300
acttgtgctg tgaaattgct attccaacaa atgatgtgaa tagtcctgat gctgaaattg 156360
gattgtgcac gttatctgca tttgtgttgg ataacttcga ttggcaagac caagataaaa 156420
ttaatgaatt ggcagaagtc caagttcgtg ctcttgataa tcttttggat taccaaggat 156480
atccagttcc tgaagcagaa aaagctaaaa agcgtcgtaa ccttggtgta ggtgttacta 156540
actatgcagc ttggctggca agtaactttg cttcttatga agatgctaac gatttaacac 156600
atgaactatt tgagagatta cagtatggac tcattaaagc atccattaag ctcgccaaag 156660
aaaaaggacc ttgcgaatat tattcagaca ctcgttggtc tcgaggcgaa ttacctatcg 156720
actggtacaa taaaaagatt gaccaaatcg cagctccaaa atacgtttgt gactggtcgt 156780
cgctgcggga agaccttaag ctctttggca tccgtaatag cacattatca gcacttatgc 156840
catgtgagtc atcttcccaa gtttctaaca gtacaaatgg tatcgagcct ccacgtggac 156900
cagtctctgt taaagaatca aaagagggtt cctttaatca agtcgtgccc aatattgagc 156960
ataacataga cctatatgat tatacgtgga aattagctaa gaaaggtaat aaaccttatc 157020
ttacgcaagt agctattatg cttaaatggg tatgtcaatc agcttcagct aatacatatt 157080
atgacccgca gatttttcca aaaggaaagg ttccaatgtc aataatgatt gatgaccttt 157140
tgtatttttg gtattttggc ggaaaaaatt tctattatca taatacccgt gacggttctg 157200
gtactgatga ttatgaaata gaaactccaa aagctgaaga ttgttcatcc tgtaaattat 157260
gatataattt gactcacgga cgagtcacta tctattaact aagcggaaaa tttatgagca 157320
cagtttttaa tacaaatcca gttgatgttt taaaagaacc tatgttcttc ggttcaggtc 157380
ttggtattgc gcgttatgat attcaacgtc ataaagtttt tgaagattta accgaaaagc 157440
aattatcatt tttctggcgt cctgaagaag taaacttgat gatggatgct gcacaattta 157500
acaagcttcc tcaatatcag caagatattt ttactaataa cctgaagtat caatcacttc 157560
tagatagcat tcagggtcgt gcaccatctg ctgtacttat gtcgttaatt tcagacccaa 157620
gccttgatac atgggttgct acatggactt ttagtgaaac tattcacagt cgttcataca 157680
ctcatatcat gcgaaatctt tatactgatc catcaaaggt atttgatgag attgtattag 157740
ataaagctat tatgaaacgt gccgagtcca ttggtcgcta ttacgatgat gttctagtta 157800
agactcgtga atatcagaat gcggttgaag attatgaagg aattttatca gaaggatttc 157860
ataaagaaga gctaggcaaa gttgttgaat atactaaacg ggcactaatg aaatctcttt 157920
atctttgcct tcatgtaatc aacgcattgg aagctattcg tttttatgta tctttcgcat 157980
gtacctttaa cttccataaa aacatggaaa tcatggaagg taatgccaag attatgaagt 158040
tcattgctcg tgatgaacag cttcacctta aaggtaccca atatattatt cgtcaacttc 158100
aacttggcac tgatggtgat gaatgggtta aaatcgccca agagtgtgaa caagaagcag 158160
ttgatatttt tatggaagtc aaccgccaag aaaaagactg ggcagttcat ttatttaaag 158220
atggcgatgt tcctggatta aatacaaata gcatgtggag ctttattgat tacttaactg 158280
tatctcgtat gaaacagtgc ggtcttccat gcccaattac cgatgctccg gttaaacacc 158340
cgtatccttg gattcgtgaa tatcttaatt ctgataatgt tcaatccgcg ccacaagaag 158400
tagaactgtc atcttatctt gtagcacaga ttgataatga tgttgatgat aaagttatga 158460
tgagttttaa aaaatatttt taaggagtgg gccgcaaggc ccattttatt atgaaagaaa 158520
ttgcaacaga atattcattt attaaatata ctgagctaga attagacgac aacggaagta 158580
taaaacaatt atccattcca aacaagtata acgtaattta tgctattgct ataaatgatg 158640
agcttgttta tattggaaaa actaaaaatt tacgtaaaag aataaattat tatagaactg 158700
ctattaatcg taaagacaaa acgtctgatt ctactaaatc tgcattaatt catgctgcgc 158760
taaaggaagg aagcaaagtt gaattttacg cccgccaatg ttttaatctt tctatgacaa 158820
atgagttagg tacaatgaca atcgcaacga ttgacctaga ggagccgcta ttcattaaac 158880
tgtttaaccc gccttggaat attcaacaca agaaaaaatg atgcttccac atggagtgtg 158940
gtactatatt caaaacacaa aagaggatac acaatgcaag aactttttaa caatttaatg 159000
gaactatgta aggattcaca gcgtaagttt ttttactcag atgatgtaag tgcatctgga 159060
agaacttaca gaattttctc atataattat gcatcttatt ctgattggtt acttccagac 159120
gcattagaat gtcgtggaat tatgtttgaa atggatggag aaaaaccggt aagaatcgct 159180
tctcgtccta tggaaaagtt ttttaacttg aatgaaaatc cattcacgat gaatatcgat 159240
ttaaatgacg tcgattacat tctaacaaaa gaagacgggt ctttggtatc aacttattta 159300
gacggtgatg aaattctgtt caaatcaaag ggttcaatca aatctgagca ggctttaatg 159360
gctaatggaa ttttgatgaa tattaatcat caccagttgc gcgacagact taaaaaatta 159420
gccgaagatg gatttactgc taactttgaa ttcgttgctc cgacgaatag aatcgttctt 159480
gcttatcaag agatgaaaat cattttattg aatattcgtg aaaatgaaac aggcgaatac 159540
atttcatatg atgatattta taaagatgct attcttcgtc catatctagt tgaacgatac 159600
gaaatcgata gtcctaaatg ggtagaagaa gctaaaaatg cagaaaacat cgaaggctat 159660
gttgccgtga tgaaagatgg ttctcatttt aaaattaagt ctgactggta cgtgtctctt 159720
cacagcacaa aaagttcatt agataatcca gaaaaattgt ttaagactat tattgatggt 159780
gcatcagatg atcttaaagc aatgtacgct gacgatgaat attcatatag aaaaattgaa 159840
gcatttgaaa cgacttatct gaagtactta gaccgagctc tgtttttagt tcttgactgt 159900
cacaataagc attgcggcaa agatagaaag acttatgcaa tggaagcgca aggcgttgct 159960
aaaggtgctg gaatggaaca tctgttcggt atcatcatga gcctctacca agggtatgat 160020
agtcaagaga aggtcatgtg tgaaatcgaa cagaattttt tgaaaaatta taaaaaattt 160080
atcccagaag gatactaagc tgtttacaag tccctcgtgt tgtgttatag tagtcttact 160140
gacataacat gaggacttta tgatggattt gcagcttatt actactgaga tggtcgttga 160200
agcatacggt gatactacag atgggatttc tgtatttaaa ggaaatcgtc gagttggata 160260
tatcaccgat cttaagaaag atttagctaa gcaagtcaag cggaaaacga ccattaaaga 160320
atatcgaaat cgtcgtcttg agcaagcccg tgatatgctt cctgatgcgg ttgaggagat 160380
gaaagtcttt ttagaaaatc agcttgcgaa atatgattgt gatgtgttca ttaatcagac 160440
tcaacctaat gttcatatta acaactgtaa atgctatatc atcgttaatc ctttaacggg 160500
aaaacatcgt cttggaatta gtaatccaaa tcgtagtgca tcggatatgg cagaagatgt 160560
tgaggcatgc tttaaaattt ctaaatctcc ggctgaacat catattttaa ttaacggtct 160620
ttctcaagac gatattatag aggttattaa aactttatgc aattaagtaa tacgacaaca 160680
ggcttgctat taattgtaat tgcattgggc ggaacttctt taattttaaa aaataaaatt 160740
gaaagattag aaacgtctgt tgtagaaatt acaaaaacgg ccaatgaaaa cgctttagca 160800
ttaaataatt tgcgaattca gtataattat attgatgcga tgaataataa aaatcgtgag 160860
gcaattgctg ctattgagcg tgaaaatgaa aaactgcgca aagacgcaaa gaaggcggat 160920
gtggtggctc ataagccagg attggttgaa aaacaaatca acaactcctt caacaagttc 160980
gcagaagaca tccaggacct ttctaaatga ttaaactatc agcagtaata ttatctattg 161040
gtcttctagt tggttgttcg acaaagcctc tagaagtaaa gaaagaaaca gttcatccta 161100
attggccagt acaaataaag tcatacgatg aagctaaact atcctggcaa gttaaagtta 161160
ttgatggtaa agcttgggtc ggtatgccat tcgaagattc ccaggaattt cgtatttggc 161220
ttaatgatgt aaaacgatat gtacatgatc agaaaactat gatatgttat tatcgccaag 161280
agttaaaaga ggataaatgc aaatgatttc atggcatcaa tttgaacatc tcaaaggatt 161340
gatttatgaa tccgagatgg ctgcaatgat ttacggacgc cagattcagc ggttagaatc 161400
tttacctcca actaatgatg ttttattagc tcaatctcgt gctaatctta aaaatgaata 161460
ccaaaataag tggggtaaag catctaaaga cctgcatgat tatattcaat cattggttga 161520
gaaataataa atgaaaactc tgttagaacg ttatattgaa tgttcagacc gttacattga 161580
tgcatgccgc ggtgcagtat atatggattt ggaccgcggg gtagtattaa atgatgaaga 161640
ccctgcgaaa gctttagatg atgcaggtaa agcattacga aaagaagcaa aagcccgtgg 161700
gcttgatatg tatcagctta aaaatcacat gataaaattt atttcatcca atgttcagag 161760
caaatcggtg aatcaatcaa cagctgaatt gtataaagga cggcgtgagc ataatattcg 161820
tattcttgaa gttttcttag gaattaaatg atgaaaaaga ttattttgac tgttggatgt 161880
cctggttcag gtaagagcac ttgggctcgt gaatttattg ctaaaaatcc tggattttat 161940
aatatcaatc gtgatgatta tcgtcaatcc atcatgggcc atgaagaacg cgacgagtat 162000
aagtatacca aaaagaaaga aggtatcgta actggtatgc agtttgatac agctaaaagt 162060
attctgtacg gtggcgattc tgttaaggga gtaatcattt cagatactaa cctgaatccc 162120
gaacgacgac tagcatggga aacttttgcc aaagaatacg gctggaaagt tgaatataaa 162180
gtgtttgatg ttccttggac tgaattggtt aaacgtaact caaaacgtgg aactaaagca 162240
gtaccaattg atattttacg ttcaatgtat aaaagcatgc gagagtatct cggtcttccg 162300
gtatataaag ggactcctgg taaaccaaaa gcagttattt ttgatgttga tggcacatta 162360
gcaaaaatga atggtcgcgg tccttatgac cttgaaaaat gtgatactga tgttatcaat 162420
cctatgattg ttgaactagc taagatgtac gataagcaag gatattacat tgtagtcgtt 162480
tcaggccgtg aaagtggaac cgaagaagac ccaacgaaat attatcgtat gacccgtaaa 162540
tgggttgagg atattgctgg cgttccatta gttatgcaat gtcaacgcga acaaggtgat 162600
acccgtaaag atgatgtagt taaagaagaa attttctgga aacacatcgc accgcatttt 162660
gatgtgaaat tagctattga tgaccgtaac caagtcgttg agatgtggcg tcgtatcggt 162720
gttgaatgct ggcaagttgc ttatggagat ttttaatggc gtggcatcat gaaacttggt 162780
ctattgttat tgtaaatagt ggtttagttg gtactagtaa tgggcaattt tgtgtattca 162840
ctagtgaaat cagagcttgg gaggaatgtc ttaaattaag agaaaagaat cctgatgttg 162900
aactaacagt aaagaaaact aaactgcctt taccatggaa aacttatgaa taacatagaa 162960
aagatttatc aactttgcga taaaattgaa aaagaaaaga aatatctatt ttgtttatgg 163020
cctattgttg atggaagaat agacttagat attcttgatt atgaaacaga agacatagta 163080
gatggttcaa cttttgataa tgcgttggat gttattaatt ggcttgaaga aaattatgtg 163140
gggtgaatat gtttccgact tattctaaaa tcgtagaagt agtgtttagt caaattatcg 163200
ctaataatat gtttgaaaag cttgataacg cagccgagct tcgaattcat gctcaagtga 163260
ctcatgtatt gaacactttg cttccagacc aggtggattc tattgcaatt acgctgtatc 163320
cgggttccgc gcatatcatt gtcgtatttg gtcttgatgc tgagctagtt atcaaaggcg 163380
atattcgttt tgaatcgcag acatcagaat tcaaagcaat ttaatagttt actttacggt 163440
agagttgtga tattatagct ctaccaaaac aaatgaggaa attgaaatga gcgaatggtt 163500
tgaagaagat aaggtttatc gctttaaagc tggatataaa gatattttta atgaaacttg 163560
tggggctaat aaacgaattg ctcagtttat tggggaaaat tcatttaaag taaaaataga 163620
tcctgcgaaa aatgttatta gcattaaacg cgaaattgac gattgctggt ataaagctgt 163680
tgatgtaatg ggcgaatcct ataaagttag cccgttattt tcaattgctt atatgttaga 163740
atattctttt ttcgaagaag ttcaaaaaga tgattctgtc agtaaatttg aaattaaaac 163800
tgataaagaa attaagtgga aagtagtagg tattactggt tgcatgtttt atatctatgc 163860
tcaaactgat acgaaggaag aagctaaaaa gaaagctcta gaatatcttg aagagtataa 163920
agaaggcccg gtaatgatta cccaagatgc cgaattagtt tctgtcaaat tagttaaaaa 163980
cgttgaaagt aaggagctgg gatcaacatg ctaagtgaaa aaccaattac tgttaaagaa 164040
ttccaagaaa aagttaaact atttgctcag gaattggtaa ataaggtttc tgaacgattt 164100
cctgaaacat cggttcgtgt tattaccgaa actcctcgtt cagtattagt aattgtgaat 164160
ccaggtgatg gtgatcaaat aacacatctt aaactggatt ttgatggatt agttgaagca 164220
caaagggtgt atggcgtact atgatgaatt taactgatat aattgataat tgtcttgaaa 164280
atgatactgg cgatcataga gcgcttgatt ctgaaacagc acagttcatt agaataactt 164340
taatgaatga tactctagtg aatagtattc atccttctgt gtatgatgct attattgtga 164400
cgaagtatcc agttgagctt cacaaaaaga tggttggtgc aatttttatt gataagaaaa 164460
accgctttaa agatgggcag aatataatta gttctgttat taaaagtata actaaacttc 164520
gtcacgaaat ttatcgtgtt gaaactgcta aatctgctta tctggtgatt atgaaatgaa 164580
agcgagtaca gtacttcaaa ttgcatattt agtatcacaa gaatcaaaat gttgctcctg 164640
gaaggtagga gcagtaattg aaaagaatgg acgtattatt tctactggat ataatggttc 164700
acctgcaggt ggtgtgaact gctgtgatta tgctgctgag caaggttggt tgctgaataa 164760
gcctaaacat actatcattc aaggtcataa gcctgaatgc gtatcgtttg gttcaactga 164820
tcgttttgtc ttggcgaaag aacaccgtag cgctcactct gaatggtcgt ctaaaaatga 164880
aattcatgct gaactaaatg cgattttgtt tgctgcacga aacggttctt caattgaagg 164940
tgctactatg tatgtaacac tttctccttg tccggattgt gcaaaagcga tagctcaatc 165000
tggaattaaa aagctggttt attgcgaaac atacgataaa aataaacctg gctgggatga 165060
tattctgcga aatgcgggta ttgaagtgtt taatgttcct aagaaaaact tgaataagtt 165120
aaactgggaa aacatcaacg aattctgtgg tgaataatga aatttcgttt ggtacagctc 165180
acagcaatta gttcttattc taacgagaac atttcatttg ctgtagagta taagaagtat 165240
tttttctcta aatggaaaca gtattataag tcagaatggg tttgtattga tagaccgtat 165300
agttggaaat ctgatttaga aaaatgccaa aaattgcttt ccactcttaa agaacgtgga 165360
acaacccata ttaaaactgt agtaggtaaa taaatgaaac tgacaactga acagaaagta 165420
gcaattcgtg aaattttgaa aactaaattg tccatggggg tttcaaacgt agtttttgaa 165480
aagtctgatg gtactattcg tactatgaaa ggcactcgtg atgcggactt tatgccaacc 165540
atgcaaactg gtaaattgac tgaatctgct cggaaagaat ctactgatat gattccagta 165600
tttgatgttg agcttggtgc atggcgaggt ttttctattg acaaattgat ttccgttaat 165660
ggtatgaaag ttgagcattt gcttcaattt attggtaaat aaatgcttta agaattattt 165720
gttattatta attcatctgt taacaaaaag gaaaaacgat gtctgaagta caacagctac 165780
caattcgtgc tgtcggtgaa tatgttattt tagtttctga acctgcacaa gccggtgatg 165840
aagaagttac agaatcagga cttattatcg gtaaacgtgt tcaaggtgaa gttcctgaac 165900
tgtgtgtagt tcactctgtt ggtcctgatg ttcctgaagg tttctgtgaa gttggtgatt 165960
tgacttctct tccagttggt caaattcgaa acgttccaca cccttttgta gctctgggtc 166020
ttaagcagcc aaaagaaatt aaacaaaaat tcgttacctg tcactataaa gctattccgt 166080
gtctttataa gtgatataaa taataatatg aattgagttt caattctatg tggtagtcta 166140
caactgagag atctgtcgaa agaagatgaa attcagaaga acgtgactac cgagttttaa 166200
tctctaacga gaatttttaa atgattaaac aattacaaca cgctcttgaa ctgcaacgaa 166260
acgcatggaa taatggtcac gaaaactatg gcgcatctat tgatgttgaa gccgaagctc 166320
ttgaaatcct gcgttatttc aaacatctga atcctgctca aactgcatta gctgctgagc 166380
ttcaggaaaa agatgaactt aaatatgcta agccactggc ttctgctgca cgaaaagcag 166440
ttcgtcactt tgtggtaaca ctgaagtaag tatgatgacg ggtttatggt tatcctggtc 166500
gttaaatatt caaaaaccta tgttcccctt gagggcttgc gcaggcaatg ccaataagtc 166560
ctgcattttc atttaaaaga gaatttataa tggcaaaaca agctaaagca aagaaagcag 166620
ttgaaaagaa agttggtgat tctaaacgcg ctggctacaa gcgtgggtcg aactctcgta 166680
tcaatcaaac tgttgagaag atcatgcgcc gagcacgtgc ggttcttcga gatgatgctt 166740
ctcgttttgg taagcagaaa gcataagttg aggactcctt cgggagtcct tttttatttt 166800
ccaaagattg cacaaagttg tttacagtat ggttcctttg tgatagtatt atcttacaca 166860
aacaaaggag aataaaatga aaacaattaa tctgaacgct gcagttaaaa ctaaatgctt 166920
caacggtaaa tatgatgaaa ctatgtggtt cttaatggca gttgaaggtg atattattga 166980
agtagaaaca acagaaggta tgggaacaga tttcaccttt acaattcaag ttcataattt 167040
ctttactggt tggatttatg aattgaacac agtaatcgtt ggaaaaattg aacaaaatga 167100
attgggtgaa tggtattatg ttacagctcg ccaacgtgcc gaacgcttaa ttgagaagat 167160
gaaaaaagtt ggtaaacttg acatgcagca ctggaaagta gtaaaataat tgtttacttt 167220
ggtacaggat atgatattat atacctgtac cgcaattaaa catcttggag aataaaaatg 167280
aactacatca actttgaacg taaatatgtt tctaatggta ttgcaggttc tattgatact 167340
atttgccttt ggaaacatca aaatggatca gtatgcgaaa ttgaacagta tatgacccct 167400
aactacgttt atatgcgatt tgaaaatggc atcacggttt caatcacaat ggaaggttcc 167460
aacttcaaaa tcgctctgga tgatgatttt cgtcaacgcg atttagggac tcatccttgc 167520
tggaatggtg ttaatcgcaa gcttctggtt aaaacttgga ttcgtcatat tctgagtaac 167580
agagctaaac ctgagcatct tgaagcaatc tttgatgtag ttcttaacga atttgatatt 167640
taaaataaaa caggggcttc ggccccttac tgaggaaaat actatgttta tgactactta 167700
ttttgatacc cgcaaaaatt tctgtgaagt ggttttctct aaggcgccta aagaccttcc 167760
tgctcatttg caacctacca gcgaatcgat taaaaactac gttaatgtag tctgtccttt 167820
agagttccgt acagtaaatg ggcgcgatac tttagctatc gctaaactca atcgtgaaat 167880
tgacattgac ccttcaattg cgcgtgaaat taatatttct gatattggcg gcggtaatgt 167940
taaatcgcat ggttttcaga tgaggttcta atgaaattct ttttaggtca aactgttgaa 168000
ttaaagggag ttggtatacc tggattaatt tctaaggttt tacctccatt taaatggagt 168060
ggtgttcaaa taaaagaggc ttatattgtt tcttgggtag atggaaatga agaccttcgt 168120
atgggtgatg aattatctcc tatttacgga ttaaaggaat t 168161

Claims (5)

1.一种从自然界分离并能够特异性地杀死肠侵袭性大肠杆菌的肌尾噬菌体科噬菌体Esc-COP-4,其具有由SEQ ID NO:1的核苷酸序列表示的基因组(登记号:KCTC 12663BP)。
2.一种用于预防和治疗肠侵袭性大肠杆菌感染的组合物,其包含权利要求1所述的噬菌体Esc-COP-4作为活性成分。
3.根据权利要求2所述的用于预防和治疗肠侵袭性大肠杆菌感染的组合物,其中所述组合物用于制备饲料添加剂、饮用水添加剂或消毒剂。
4.一种预防和治疗肠侵袭性大肠杆菌细胞感染的方法,其包括向受试者施用权利要求2或权利要求3所述的包含噬菌体Esc-COP-4作为活性成分的组合物的步骤。
5.根据权利要求4所述的预防和治疗肠侵袭性大肠杆菌细胞感染的方法,其中所述组合物以饲料添加剂、饮用水添加剂或消毒剂的形式给药到受试者。
CN201580071157.6A 2014-12-30 2015-12-28 新型肠侵袭性大肠杆菌噬菌体Esc-COP-4及其用于抑制肠侵袭性大肠杆菌增殖的用途 Active CN107208067B (zh)

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PCT/KR2015/014332 WO2016108542A1 (ko) 2014-12-30 2015-12-28 신규한 장침입성 대장균 박테리오파지 Esc-COP-4 및 이의 장침입성 대장균 증식 억제 용도

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WO2016108542A1 (ko) 2016-07-07
BR112017013245A2 (pt) 2018-08-07
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