CN107206028A - 使用祖细胞治疗眼部病症 - Google Patents

使用祖细胞治疗眼部病症 Download PDF

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Publication number
CN107206028A
CN107206028A CN201580075547.0A CN201580075547A CN107206028A CN 107206028 A CN107206028 A CN 107206028A CN 201580075547 A CN201580075547 A CN 201580075547A CN 107206028 A CN107206028 A CN 107206028A
Authority
CN
China
Prior art keywords
cells
cell
derived
umbilical cord
tsp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580075547.0A
Other languages
English (en)
Chinese (zh)
Inventor
I.哈里斯
N.S.德内卡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
Original Assignee
Centocor Ortho Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Publication of CN107206028A publication Critical patent/CN107206028A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/062—Sensory transducers, e.g. photoreceptors; Sensory neurons, e.g. for hearing, taste, smell, pH, touch, temperature, pain
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/02—Coculture with; Conditioned medium produced by embryonic cells
    • C12N2502/025—Coculture with; Conditioned medium produced by embryonic cells extra-embryonic cells, e.g. amniotic epithelium, placental cells, Wharton's jelly

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Microbiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Analytical Chemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201580075547.0A 2014-12-05 2015-12-04 使用祖细胞治疗眼部病症 Pending CN107206028A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462088429P 2014-12-05 2014-12-05
US62/088429 2014-12-05
US201562126370P 2015-02-27 2015-02-27
US62/126370 2015-02-27
US201562220873P 2015-09-18 2015-09-18
US62/220873 2015-09-18
PCT/US2015/063923 WO2016090215A2 (en) 2014-12-05 2015-12-04 Treatment of ocular conditions using progenitor cells

Publications (1)

Publication Number Publication Date
CN107206028A true CN107206028A (zh) 2017-09-26

Family

ID=56092673

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580075547.0A Pending CN107206028A (zh) 2014-12-05 2015-12-04 使用祖细胞治疗眼部病症

Country Status (16)

Country Link
US (1) US20160158293A1 (https=)
EP (1) EP3258946A4 (https=)
JP (1) JP2017537702A (https=)
KR (1) KR20170093178A (https=)
CN (1) CN107206028A (https=)
AU (1) AU2015358330A1 (https=)
BR (1) BR112017011513A2 (https=)
CA (1) CA2969690A1 (https=)
HK (1) HK1250329A1 (https=)
MX (1) MX2017007207A (https=)
PH (1) PH12017500998A1 (https=)
RU (1) RU2017123184A (https=)
SG (1) SG11201704268TA (https=)
TW (1) TW201636032A (https=)
WO (1) WO2016090215A2 (https=)
ZA (1) ZA201704521B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115968400A (zh) * 2020-04-07 2023-04-14 康巴乔有限公司 冻干间充质干细胞来源的分泌蛋白质组及其用途

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
WO2018102174A1 (en) * 2016-12-01 2018-06-07 Janssen Biotech, Inc. Treatment of retinal degeneration using progenitor cells
GB201703058D0 (en) 2017-02-24 2017-04-12 Ucl Business Plc Biomarkers
JP7348892B2 (ja) * 2019-12-30 2023-09-21 佛教慈濟醫療財團法人 眼疾患を予防または治療する組成物及び方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100272803A1 (en) * 2003-06-27 2010-10-28 Sanjay Mistry Repair and regeneration of ocular tissue using postpartum-derived cells
US20130251670A1 (en) * 2011-09-13 2013-09-26 Aidan Products, Inc Treatment of Macular Edema Utilizing Stem Cell and Conditioned Media Thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2399990B1 (en) * 2003-06-27 2015-07-22 DePuy Synthes Products, Inc. Cells derived from post-partum umbilical cord for use in treatment of disease of the heart and circulatory system
EP2431460B1 (en) * 2009-05-13 2015-10-14 Medipost, Co., Ltd. Tsp-1, tsp-2 and il-17br associated with stem cell differentiation
KR101462004B1 (ko) * 2011-07-11 2014-11-19 (주)차바이오메드 탯줄 추출물의 제조방법 및 그의 용도

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100272803A1 (en) * 2003-06-27 2010-10-28 Sanjay Mistry Repair and regeneration of ocular tissue using postpartum-derived cells
US20130251670A1 (en) * 2011-09-13 2013-09-26 Aidan Products, Inc Treatment of Macular Edema Utilizing Stem Cell and Conditioned Media Thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CAO ET AL: "Human umbilical tissue-derived cells secrete bridge molecules and rescue phagocytosis in cultured retinal pigment epithelial cells from Royal College of Surgeons rat", 《INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115968400A (zh) * 2020-04-07 2023-04-14 康巴乔有限公司 冻干间充质干细胞来源的分泌蛋白质组及其用途

Also Published As

Publication number Publication date
HK1250329A1 (zh) 2018-12-14
JP2017537702A (ja) 2017-12-21
RU2017123184A3 (https=) 2019-07-17
RU2017123184A (ru) 2019-01-10
EP3258946A4 (en) 2018-08-01
TW201636032A (zh) 2016-10-16
MX2017007207A (es) 2018-01-30
PH12017500998A1 (en) 2017-12-18
KR20170093178A (ko) 2017-08-14
EP3258946A2 (en) 2017-12-27
CA2969690A1 (en) 2016-06-09
WO2016090215A2 (en) 2016-06-09
US20160158293A1 (en) 2016-06-09
AU2015358330A1 (en) 2017-06-08
BR112017011513A2 (pt) 2018-07-10
SG11201704268TA (en) 2017-06-29
ZA201704521B (en) 2019-01-30

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Application publication date: 20170926

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