CN107174636A - It is a kind of to treat Chinese medicine of rheumatic pain and preparation method thereof - Google Patents
It is a kind of to treat Chinese medicine of rheumatic pain and preparation method thereof Download PDFInfo
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- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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Abstract
The invention discloses a kind of Chinese medicine for treating rheumatic pain and preparation method thereof, it is prepared from by the raw material of one plant of marasmius androsaceus kind and following components by weight percent：Wild white local tyrant's soaking water 100-150, wheat bran 50-75, wheat husk 20-25, ganoderma lucidum 10-15, cassia twig 10-15, windproof 10-15, Ligusticum wallichii 10-15, safflower 10-15, Radix Angelicae Sinensis 5-15, levisticum 10-15, bark of ash 10-15, root of Dahurain angelica 10-15, black soya bean 5-15, madder 10-15, pseudo-ginseng 5-15, pawpaw 5-15, Mitsubishi 5-15, lopseed 10-15, Soil unit 5-10, Radix Codonopsis 10-15, Chinese ephedra 10-15.The present invention can significantly improve medicinal fungi solid fermentation mycoplasma drug effect, can effectively alleviate, eliminate rheumatism, the pain brought to patient, its security is good, gastrointestinal irritation is slight, can effectively treat the illness such as arthralgia, joint stuffiness caused by Osteoarthritis, rheumatism etc., and cure rate is high.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of Chinese medicine for treating rheumatic pain
And preparation method thereof.
Background technology
At present, rheumatism, rheumatism are a kind of incidence of disease very high disease, patient articular
Pain and swelling, extremity numbness is aching and tired, limitation of activity, stiffness and deforming, and clinical manifestation is with heart
, can be with heating, toxaemia, fash, subcutaneous nodule, dance based on scorching and arthritis
Disease etc. is stepped, it is generally more obvious with arthritis during acute attack, as malpractice can leave throughout one's life
Deformity, has a strong impact on the health of people, brings economic loss to personal and society, is also medical science
The a great problem on boundary, traditional Chinese medicine thinks that this disease is：" paralysis " category, refers to have chill, wet
The exopathogens such as heat attack human body, impatency passages through which vital energy circulates, caused by QI-blood circulation is not smooth.Western medicine is thought
This disease is caused a kind of urgency of recurrent exerbation after the infection of the upper respiratory tract caused by hemolytic streptococcus
Property or chronic systemic connective tissue inflammation disease, western medical treatment be with anti-inflammatory analgetic, closing swash
Element traction, ultraviolet irradiation, the method for operation, it has the disadvantage to cure the symptoms, not the disease, and some disappear
Scorching anodyne has side effect, to stomach, and liver kidney organ brings infringement, during the traditional Chinese medical science is using taking orally
Medicine, which reaches, stimulates the circulation of the blood and cause the muscles and joints to relax, and purpose promoting blood circulation and removing blood stasis is often taken not to treat because formula is changeable
Convenient, DeGrain, curative effect is not lasting, high recurrence rate, and some Chinese medicines are to stomach also spinosity
Swash, should not take for a long time.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine for treating rheumatic pain and its preparation side
Method, to solve above-mentioned technical problem.
The present invention uses following technical scheme to achieve the above object：
A kind of Chinese medicine for treating rheumatic pain, by one plant of marasmius androsaceus kind and following weight
The raw material of component is prepared from：Wild white local tyrant's soaking water 100-150, wheat bran 50-75,
It is wheat husk 20-25, ganoderma lucidum 10-15, cassia twig 10-15, windproof 10-15, Ligusticum wallichii 10-15, red
Flower 10-15, Radix Angelicae Sinensis 5-15, levisticum 10-15, bark of ash 10-15, root of Dahurain angelica 10-15, black soya bean 5-15,
Madder 10-15, pseudo-ginseng 5-15, pawpaw 5-15, Rhizoma Sparganii 5-15, lopseed 10-15, Soil unit
5-10, Radix Codonopsis 10-15, Chinese ephedra 10-15, cuttlebone 10-15, rhizoma atractylodis macrocephalae 5-10.
It is preferred that, the Chinese medicine of the treatment rheumatic pain, by one plant of marasmius androsaceus kind and with
The raw material of lower components by weight percent is prepared from：Wild white local tyrant's soaking water 150, wheat bran 75, wheat
Husk 25, ganoderma lucidum 15, cassia twig 15, windproof 15, Ligusticum wallichii 15, safflower 15, Radix Angelicae Sinensis 15,
Levisticum 15, bark of ash 15, the root of Dahurain angelica 15, black soya bean 15, madder 15, pseudo-ginseng 15, pawpaw 15,
Rhizoma Sparganii 15, lopseed 15, Soil unit 10, Radix Codonopsis 15, Chinese ephedra 15, cuttlebone 15, stir-fry are white
Art 10.
A kind of Chinese medicinal preparation method for treating rheumatic pain, comprises the following steps：
(1) peace is taken to fall one plant of Marasmius strain, triangular flask of the access by sterilizing after switching activation
Fluid nutrient medium in be inoculated with after be placed in 22-26 DEG C of insulating box and carry out interval concussion and cultivate extremely
Seedling mycelium is in fine particulate, and nutrient solution color progressively becomes faint yellow, should during no living contaminants
With；
(2) by weight component weigh ganoderma lucidum 10-15, cassia twig 10-15, windproof 10-15, Ligusticum wallichii 10-15,
Safflower 10-15, Radix Angelicae Sinensis 5-15, levisticum 10-15, bark of ash 10-15, root of Dahurain angelica 10-15, black soya bean
5-15, madder 10-15, pseudo-ginseng 5-15, pawpaw 5-15, Rhizoma Sparganii 5-15, lopseed 10-15,
Soil unit 5-10, Radix Codonopsis 10-15, Chinese ephedra 10-15, cuttlebone 10-15, rhizoma atractylodis macrocephalae 5-10, so
Smalls shape is ground into pulverizer afterwards, wild white local tyrant's immersion of 1/2nd weight is put into
Slow fire, which is decocted, in water changes big fire and decocts after 40-60 minutes after 30-40 minutes, cool down standby；
(3) the middle liquid medicine and the dregs of a decoction after above-mentioned cooling are admixed wheat bran 50-75 and the wheat of components by weight percent
Stirred in husk 20-25, add wild white local tyrant's leaching of remaining two point of one weight
Stirred in soaked, moisture content in medium is 55%-65% in hand during mixing,
It is fitted into the culture medium made in seed bottle, sterilize 130 DEG C of -150 DEG C of sterilizings in pressure cooker
120 minutes or sterilizing 10-12 hours of 100 DEG C of use normal pressure, inoculating hood is put into after sterilizing cooling
Middle carry out suffocating sterilization, is inoculated with, and seed bottle is placed on after inoculation 22 DEG C -24 DEG C of interior
Fermented and cultured is carried out, is completed through fermentation in 35-45 days, culture medium is dug out progress after the completion of fermentation
Dry or dry, size-reduced machine crossed after crushing 60 mesh sieves Chinese medicinal powder.
It is preferred that, the fluid nutrient medium includes the raw material of following ratio：Wheat bran 15%, grape
Sugar 3%, corn steep liquor 0.5%, yeast extract 0.2%, magnesium sulfate 0.05%, potassium dihydrogen phosphate 0.1%.
It is preferred that, the Chinese medicinal powder being prepared from is according to weight Chinese medicinal powder and high spirit
1:10 proportions take in the morning and evening into medicinal liquor.
It is preferred that, the Chinese medicinal powder being prepared from is processed further concentration and is made 1:1.35 medicinal extract.
It is preferred that, medicinal extract, which is made externally applied ointment or adds starch, is made oral capsule or tablet, takes
Used time coordinates one spoonful of honey of addition to take.
Pharmacology analysis：
CNNS's Marasmius [Marasmius androsaceus (Lo:Fr.) Fr.] it is subordinate to basidiomycetes Asia
Door, Agaricales Kou Mo sections umbellule skin category, are commonly called as Marasmius equicrinis Muell, are tested through pharmaceutical chemistry pharmacologic effect
CNNS's Marasmius is proved to people's no adverse reaction safely with safety testing, and chemical composition is main
Mainly contain polysaccharide, amino acid, adenosine, mannitol, lactone, organic acid, cumarin, three
Ten carbonic acid, palmitate, ergosterol, β-sitosterol, r lactones, total alkaloid have
The composition of analgesic activity has 30 carbonic acid, lactone, ergosterol, palmitate, alkaloid.
Main treatment traumatic injury, fracture pain, leprosum neuralgia, sciatica and antimigraine,
Rheumatic closes the disease such as inflammation, the effects such as with analgesic, promoting blood circulation, anti-inflammatory.
Local tyrant, also known as meat ganoderma lucidum, depending on meat, poly- meat.Classification system [Ganoder Ganoder maluadum]
Slime mold complex.Composition：Slime mould, fungi, the compound of bacterium.Effect is to improve cell to exempt from
Epidemic disease,《Compendium of Materia Medica》Described in it be this through top grade, food, makes light of one's life by commiting suicide not old long, macrobiosis angle.
The water soaked with it, which has, to purify water, the effect of demineralized water.Trace element in water is in warp
Its absorption, decomposition, metabolism are crossed, is also activated.
Ganoderma lucidum, bitter, flat, nontoxic, effect is invigorating heart gas, in the heart knot, bowl spares, hard muscles and bones, Li Guan
Section.Chemical composition：Polysaccharide, triterpenes, ucleosides, sterols, alkaloids, albumen
Matter, amino acid polypeptide class, various trace elements, mannitol etc..
Cassia twig：Pungent-warm, nontoxic, effect is sweating expelling pathogenic factors from muscles and skin.Warming meridians and promoting circulation of qi, helps yang transforming qi, cold dispelling stop
Bitterly, chemical composition：Cumarin, cinnamic acid, flavonoids, steroid.
It is windproof：Sweet temperature is nontoxic, cures mainly：It is in fashion the whole body, arthralgia, hypochondriac pain, side of body wind, four limbs contraction
It is anxious.Chemical composition：Coumarin, glycoside, lactone, phenols psoralen, mannitol.
Ligusticum wallichii：It is pungent, warm, nontoxic cure mainly apoplexy enter brain headache, arthritis spasm emergency, all cold gas,
Impatiently swell and ache, coerce wind pain, waist pin weakness, hemiplegia.Chemical composition：Cupreol,
Lactone, palmitic acid etc..
Safflower：It is pungent, warm, nontoxic, effect：Invigorate blood circulation, blood stasis removing analgesic, abdominal mass lump in the abdomen, bruise
Damage, chemical composition：Palmitic acid, flavonoids, containing carthamin, neocarthamin, safflower quinone glucoside,
Safflower polysaccharide, palmitic acid, cinnamic acid, laurate, cupreol, stigmasterol.
Radix Angelicae Sinensis：It is sweet, warm, nontoxic, effect：Evil in warm in pain, arthritis with fixed pain caused by dampness, tonifying five zang organs, myogenic meat,
Control a wind cutting, all blood benefit, all labor, broken extravesated blood, foster new blood, chemical composition：Palmitic acid,
Sitosterol, lactone, vitamin A, vitamin B1, vitamin B12, several amino acids, courage
Alkali.
Levisticum：It is bitter, sweet, flat, nontoxic, cure mainly：Chill is hit, metal-inflicted wound is relieved pain, hundred section gouts,
The strain of brothers' contraction, wind toxin dentalgia, hands and feet caused by paralysis, chill temperature numbness, meciless, neck of aching be difficult to be stretched,
Pain along spinal column, chemical composition：Coumarins, lactone, angelol.
Bark of ash：It is bitter, flat, nontoxic, cure mainly fever and chills perverse trend, warm and humid wandering arthritis, the arthrodynia of extremeties, the whole body contraction be anxious,
Blood-nourishing honor muscle, chemical composition：Alkaloid, carbohydrate.
The root of Dahurain angelica：Pungent, warm, nontoxic, effect is to lose purulence, only pain in the chest and abdomen, blood shouting pain, pain in the back, head
Bitterly, dentalgia, pain in the supra-orbital bone, knife arrow metal-inflicted wound, chemical composition：Cumarin, lactone, palmitic acid.
Black soya bean：Sweet, flat, nontoxic, effect is：Eliminating impediment goes to swell, gets round by bribery, control wandering arthritis pain, it is pained,
Muscle goinyalgia, turgor, chemical composition：Choline.
Madder：It is bitter, cold；With cool blood, stop blooding, go hemostasis, promoting blood circulation the effects such as.
Pseudo-ginseng：Sweet, slight bitter is warm-natured；HaveIt is promoting blood circulation and removing blood stasis, the effects such as analgesic therapy wind-dispelling.
Rhizoma Sparganii：Pungent, hardship, puts down；With blood-breaking, the effects such as Xiao Ji Zhi Tong.
Lopseed：Sweet, acrid, warm；With dispelling wind and eliminating dampness, stimulate the circulation of the blood and cause the muscles and joints to relax, promoting blood circulation and stopping pain, removing toxic substances
The effects such as changing rash.
Soil unit：Alias ground beetle, ground beetle, with blood coagulation resisting function, can improve and reinforcement in it is main
The effects such as blood supply of organ, tissue and whole body.
Radix Codonopsis：It is sweet, it is mild-natured；With tonifying middle-Jiao and Qi, quench the thirst, strengthening spleen and tonifying lung the effects such as.
Chinese ephedra：Warm-natured, pungent, slight bitter, its alkaloid enriches, for arthralgia pain due to rheumatism, cloudy subcutaneous ulcer,
The effects such as with inducing diuresis for removing edema, sweating cold dispelling.
Cuttlebone:With dehumidifying, relieving haperacidity, hemostasis, effect of sore.The traditional Chinese medical science, which is usually used in treating for stomachache, to be gulped down
Acid, analgesic, hemostasis and gastric ulcer.
Rhizoma atractylodis macrocephalae：Honey wheat bran is sprinkled into hot pot, bighead atractylodes rhizome piece is added when smoldering, fry to coke yellow,
Burnt odor gas is escaped, takes out, weeds out honey wheat bran；With strengthening the spleen and replenishing qi, the effects such as eliminate dampness and have diuretic effect,
《Medicine origin》Record：" dehumidifying benefit is dry, and middle QI invigorating, middle benefit gas, goes wet in taste, removesStomach energy, strong taste enter diet, quenched the thirst, antiabortive.”
The beneficial effects of the invention are as follows：The present invention can make medicinal fungi solid fermentation mycoplasma drug effect
Significantly improve, can effectively alleviate, eliminate rheumatism, the pain brought to patient, its security
Good, gastrointestinal irritation is slight, can effectively treat arthritis caused by Osteoarthritis, rheumatism etc.
Bitterly, the illness such as joint stuffiness, cure rate is high.
Embodiment
With reference to specific embodiment, the present invention is further elaborated.
Embodiment 1
A kind of Chinese medicine for treating rheumatic pain, by one plant of marasmius androsaceus kind and following weight
The raw material of component is prepared from：Wild 100 grams of white local tyrant's soaking water, 50 grams of wheat bran, wheat
20 grams of husk, 10 grams of ganoderma lucidum, 10 grams of cassia twig, windproof 10 grams, 10 grams of Ligusticum wallichii, safflower
10 grams, 5 grams of Radix Angelicae Sinensis, 10 grams of levisticum, 10 grams of bark of ash, 10 grams of the root of Dahurain angelica, 5 grams of black soya bean,
10 grams of madder, 5 grams of pseudo-ginseng, 5 grams of pawpaw, 5 grams of Rhizoma Sparganii, 10 grams of lopseed, Soil unit 5
Gram, 10 grams of Radix Codonopsis, 10 grams of Chinese ephedra, 10 grams of cuttlebone, 5 grams of rhizoma atractylodis macrocephalae.
Embodiment 2
A kind of Chinese medicine for treating rheumatic pain, by one plant of marasmius androsaceus kind and following weight
The raw material of component is prepared from：Wild 150 grams of white local tyrant's soaking water, 75 grams of wheat bran, wheat
25 grams of husk, 15 grams of ganoderma lucidum, 15 grams of cassia twig, windproof 15 grams, 15 grams of Ligusticum wallichii, safflower
10 grams, 5 grams of Radix Angelicae Sinensis, 10 grams of levisticum, 10 grams of bark of ash, 10 grams of the root of Dahurain angelica, 5 grams of black soya bean,
10 grams of madder, 10 grams of pseudo-ginseng, 10 grams of pawpaw, 10 grams of Rhizoma Sparganii, 10 grams of lopseed, soil
5 grams of member, 10 grams of Radix Codonopsis, 10 grams of Chinese ephedra, 10 grams of cuttlebone, 10 grams of rhizoma atractylodis macrocephalae.
Embodiment 3
A kind of Chinese medicine for treating rheumatic pain, by one plant of marasmius androsaceus kind and following weight
The raw material of component is prepared from：Wild 150 grams of white local tyrant's soaking water, 75 grams of wheat bran, wheat
25 grams of husk, 15 grams of ganoderma lucidum, 15 grams of cassia twig, windproof 15 grams, 15 grams of Ligusticum wallichii, safflower
15 grams, 15 grams of Radix Angelicae Sinensis, 15 grams of levisticum, 15 grams of bark of ash, 15 grams of the root of Dahurain angelica, 15 grams of black soya bean,
15 grams of madder, 15 grams of pseudo-ginseng, 15 grams of pawpaw, 15 grams of Rhizoma Sparganii, 15 grams of lopseed, soil
10 grams of member, 15 grams of Radix Codonopsis, 15 grams of Chinese ephedra, 15 grams of cuttlebone, 10 grams of rhizoma atractylodis macrocephalae.
The preparation method of the Chinese medicine of rheumatic pain is treated in above-described embodiment, is comprised the following steps：
(1) peace is taken to fall one plant of Marasmius strain, triangular flask of the access by sterilizing after switching activation
Fluid nutrient medium in be inoculated with after be placed in 22-26 DEG C of insulating box and carry out interval concussion and cultivate extremely
Seedling mycelium is in fine particulate, and nutrient solution color progressively becomes faint yellow, should during no living contaminants
With；
Component weighs above-mentioned Chinese medicine by weight, and smalls shape is then ground into pulverizer, is put into
Slow fire, which is decocted, in wild white local tyrant's soaking water of 1/2nd weight changes big after 30-40 minutes
Fire was decocted after 40-60 minutes, was cooled down standby；The fluid nutrient medium includes the original of following ratio
Material：Wheat bran 15%, glucose 3%, corn steep liquor 0.5%, yeast extract 0.2%, magnesium sulfate
0.05%, potassium dihydrogen phosphate 0.1%.
Middle liquid medicine and the dregs of a decoction after above-mentioned cooling is admixed wheat bran 50-75 and the wheat of components by weight percent
Stirred in husk 20-25, add wild white local tyrant's leaching of remaining two point of one weight
Stirred in soaked, moisture content in medium is 55%-65% in hand during preparation,
It is fitted into the culture medium made in seed bottle, sterilize 130 DEG C of -150 DEG C of sterilizings in pressure cooker
120 minutes or sterilizing 10-12 hours of 100 DEG C of use normal pressure, inoculating hood is put into after sterilizing cooling
Middle carry out suffocating sterilization, is inoculated with, and seed bottle is placed on after inoculation 22 DEG C -24 DEG C of interior
Fermented and cultured is carried out, is completed through fermentation in 35-45 days, culture medium is dug out progress after the completion of fermentation
Dry or dry, size-reduced machine crossed after crushing 60 mesh sieves Chinese medicinal powder.
The Chinese medicinal powder being prepared from, is divided into equivalent several pieces, takes after mixing it with hot water daily；
Can be 1 according to weight Chinese medicinal powder and high spirit:10 proportions take sooner or later into medicinal liquor
With；Or the Chinese medicinal powder being prepared from is processed further concentration and is made 1:1.35 medicinal extract, or leaching
Cream, which is made externally applied ointment or adds starch, is made oral capsule or tablet.Wide variety, is adapted to not
The patient of same type uses.No matter Chinese medicine of the present invention takes orally or external application, daily once in the morning and once at night,
15 days are a course for the treatment of, and three days pain of general patient's medication is that can obviously relieve, through one or two
See that symptom is clearly better after course of therapy, adhering to taking thoroughly to cure.
Experimental example, in order to verify specific curative effect of this Chinese medicine to treatment rheumatic pain, for just
The rheumatisant examined 100, age 30-60 Sui, takes Chinese medicinal powder of the present invention every daily
Day once in the morning and once at night takes with warm water, and coordinates one spoonful of hydromel of addition to take when taking.Treatment
Three courses for the treatment of (one and a half months) cure patient 86, hence it is evident that improvement patient 14, invalid to suffer from
Person without.
Present invention treatment model case：
1. pairs of XX of case, man 43 years old, is engaged in underground coal mine work, because underground labor intensity is big,
Plus bad environments, suffer from lumbago due to wind-wetness evil disease, frequent hurt like hell, it is impossible to normal work, once
Chinese medicine, Western medicine are taken without positive effect, is matched somebody with somebody for 40 grams with this active compound powder in July, 2015
The proportional arrangement medicinal liquor of 50 degree of one jin of white wine is taken to him, and patient feels that waist starts gently after 3 days
Pine, pain in the back starts to alleviate after 5 days, and pain relief was taken after 15 days, and pain in the back symptom disappears,
Start working work, adhere to taking this medicine always in work to withdrawing after 60 days, then always
Work, does not recur so far.
The poplar XX of case 2, man 67 years old, suffers from rheumatic leg pain disease more than 2 years, patient feels that leg is passed through
Normal pain, unbearably, exacerbation of symptoms of suffering from cold to the wind also suffers from waist dish outstanding, frequent waist to numbness
Bitterly.In July, 2015, I is condensed into 1 with this raw material medicinal powder:1.35 medicinal extract takes to him
With, each taking 1 gram, three times a day, take patient after 3 days and felt that Low Back Pain has a pain in the leg mitigation,
Take pain after 1 month to disappear, leg also has hypodynia, then use 40 grams of raw material medicinal powder to match somebody with somebody 50 degree
1 jin of proportions medicinal liquor of white wine is treated to him, after 3 months, and patient feels to have fully recovered, and stops
Medication wine, does not recur so far.
Case row 3 female, 63 years old pain in the back, skelagia nearly 5 years, poultry also has fox in family, daily to chicken
Feeding, picks up egg, and the body of Low Back Pain does not get up directly, leg also often pain, many places are sought over nearly 5 years
Doctor asks medicine, all swears an oath in all solemnity everywhere, it is ensured that cure, takes ineffective after being gone home by medicine
Really, economy is suffered a loss, and slight illness is not got better, and patient almost loses treatment confidence, 2015 years 8
In month, I is treated with 40 grams of proportional arrangement medicinal liquor with 1 jin of white wine of raw material feed powder to him,
Take and feel that waist starts easily, to feel that pain in the back starts mitigation after 8 days, leg also has hypodynia after 5 days,
Continue to take treatment, adhere to taking low back pain symptom disappearance in 45 days, waist is without any pain, leg
Also keenly feel, continue to take treatment, present patient take this medicine after not only body without any bad
Reaction, and feel in high spirits, digest, sleep.Energetic, muscle power increase is resistance to
Fatigue, (because patient per's flu must have an intravenous drip, and the time is all after 7-10 days for anti-flu
It could fully recover, it is only all right with 2 days to take after the medicine flu, and does not have an intravenous drip, and only eats
Point cold drug).
The present invention is modern medicinal fungi fermentation and the perfect adaptation of traditional Chinese medicine, traditional Chinese medicine warp
The science of mistake is selected as the property of medicine matrix of fungi fermentation, and Chinese medicine is not only remained to greatest extent
The middle absorption of component damage and Chinese medicine through officinal fungus mycelium caused by process, point
Macromolecular substances in medicinal material are resolved into small-molecule substance by solution, conversion, metabolism, this
Small-molecule substance is planted easily to penetrate in our human body cell films, by our absorption of human body, so that compared with
The intracellular polysaccharide secreted in fast performance drug effect, and medicinal fungi thalline fermentation process, it is extracellular
Polysaccharide and nucleic acid, amino acid, alkaloid, polypeptide etc. have the composition of physiologically active, to our people
Body has regulation immune, there is remarkable effect in terms of strengthening function, comprehensively regulating, it is this with point
It is to later microbial fermentation according to the method as property of medicine matrix to analyse chemical composition in Chinese medicine
There is the impetus of Chinese medicine in terms of field, new drug development.
Claims (7)
1. a kind of Chinese medicine for treating rheumatic pain, it is characterised in that by one plant of marasmius androsaceus kind and with
The raw material of lower components by weight percent is prepared from：Wild white local tyrant's soaking water 100-150, wheat bran 50-75, Mai Gu
Shell 20-25, ganoderma lucidum 10-15, cassia twig 10-15, windproof 10-15, Ligusticum wallichii 10-15, safflower 10-15, Radix Angelicae Sinensis
5-15, levisticum 10-15, bark of ash 10-15, root of Dahurain angelica 10-15, black soya bean 5-15, madder 10-15, pseudo-ginseng 5-15,
Pawpaw 5-15, Mitsubishi 5-15, lopseed 10-15, Soil unit 5-10, Radix Codonopsis 10-15, Chinese ephedra 10-15, sea
Egg capsule of a mantis 10-15, rhizoma atractylodis macrocephalae 5-10.
2. a kind of Chinese medicine for treating rheumatic pain as claimed in claim 1, it is characterised in that by CNNS
One plant of Marasmius strain and the raw material of following components by weight percent are prepared from：Wild white local tyrant's soaking water 150, wheat
Bran 75, wheat husk 25, ganoderma lucidum 15, cassia twig 15, windproof 15, Ligusticum wallichii 15, safflower 15, Radix Angelicae Sinensis 15,
Levisticum 15, bark of ash 15, the root of Dahurain angelica 15, black soya bean 15, madder 15, pseudo-ginseng 15, pawpaw 15, Mitsubishi 15,
Lopseed 15, Soil unit 10, Radix Codonopsis 15, Chinese ephedra 15, cuttlebone 15, rhizoma atractylodis macrocephalae 10.
3. a kind of Chinese medicinal preparation method for the treatment of rheumatic pain as claimed in claim 1, it is characterised in that
Comprise the following steps：
(1) peace is taken to fall one plant of Marasmius strain, the Liquid Culture of triangular flask of the access by sterilizing after switching activation
It is in fine particulate, training to be placed in after being inoculated with base in 22-26 DEG C of insulating box and carry out interval concussion and cultivate to seedling mycelium
Nutrient solution color progressively becomes faint yellow, is applied during no living contaminants；
(2) by weight component weigh ganoderma lucidum 10-15, cassia twig 10-15, windproof 10-15, Ligusticum wallichii 10-15, safflower 10-15,
Radix Angelicae Sinensis 5-15, levisticum 10-15, bark of ash 10-15, root of Dahurain angelica 10-15, black soya bean 5-15, madder 10-15, pseudo-ginseng
5-15, pawpaw 5-15, Mitsubishi 5-15, lopseed 10-15, Soil unit 5-10, Radix Codonopsis 10-15, Chinese ephedra 10-15,
Cuttlebone 10-15, rhizoma atractylodis macrocephalae 5-10, are then ground into smalls shape with pulverizer, put into 1/2nd weight
Wild white local tyrant's soaking water in slow fire decoct and change big fire after 30-40 minutes and decoct after 40-60 minutes, it is cold
It is standby；
(3) the middle liquid medicine and the dregs of a decoction after above-mentioned cooling are admixed the wheat bran 50-75 and wheat husk 20-25 of components by weight percent
In stir, stirred in the wild white local tyrant's soaking water for adding remaining two point of one weight,
Moisture content in medium is 55%-65% in hand during mixing, is fitted into the culture medium made in seed bottle,
Sterilize 130 DEG C -150 DEG C and sterilize 120 minutes or using sterilizing 10-12 hours of 100 DEG C of normal pressure in pressure cooker,
It is put into after sterilizing cooling in inoculating hood and carries out suffocating sterilization, is inoculated with, seed bottle is placed on 22 DEG C after inoculation
- 24 DEG C of indoor carry out fermented and cultured, through 35-45 days fermentation complete, after the completion of fermentation culture medium dig out into
Row drying is dried, size-reduced machine crossed after crushing 60 mesh sieves Chinese medicinal powder.
4. a kind of Chinese medicinal preparation method for treating rheumatic pain as claimed in claim 3, it is characterised in that
The fluid nutrient medium includes the raw material of following ratio：Wheat bran 15%, glucose 3%, corn steep liquor 0.5%,
Yeast extract 0.2%, magnesium sulfate 0.05%, potassium dihydrogen phosphate 0.1%.
5. a kind of Chinese medicinal preparation method for treating rheumatic pain as claimed in claim 3, it is characterised in that
The Chinese medicinal powder being prepared from, is 1 according to weight Chinese medicinal powder and high spirit:10 proportions are early into medicinal liquor
Evening takes.
6. a kind of Chinese medicinal preparation method for treating rheumatic pain as claimed in claim 3, it is characterised in that
The Chinese medicinal powder being prepared from is processed further concentration and is made 1:1.35 medicinal extract.
7. a kind of Chinese medicinal preparation method for treating rheumatic pain as claimed in claim 6, it is characterised in that
Medicinal extract, which is made externally applied ointment or adds starch, is made oral capsule or tablet, coordinates when taking and adds one spoonful of honey
Take.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108452287A (en) * | 2018-06-20 | 2018-08-28 | 禹州市中瑞农业园林有限公司 | A kind of Chinese medicine package and preparation method for anti-rheumatism treating |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7601509B2 (en) * | 2004-07-15 | 2009-10-13 | Power Laura W | Biotype diets system: predicting food allergies by blood type |
| CN103816254A (en) * | 2014-03-10 | 2014-05-28 | 山西善蒸堂生物科技有限公司 | Chinese herba preparation for treating anemofrigid-damp arthralgia and muscle and bone strain and application method of Chinese herba preparation |
| CN104830696A (en) * | 2015-04-19 | 2015-08-12 | 吉林大学 | High-yield Marasmius androsaceus mutant strain and cultivation method |
-
2016
- 2016-03-09 CN CN201610131731.9A patent/CN107174636A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7601509B2 (en) * | 2004-07-15 | 2009-10-13 | Power Laura W | Biotype diets system: predicting food allergies by blood type |
| CN103816254A (en) * | 2014-03-10 | 2014-05-28 | 山西善蒸堂生物科技有限公司 | Chinese herba preparation for treating anemofrigid-damp arthralgia and muscle and bone strain and application method of Chinese herba preparation |
| CN104830696A (en) * | 2015-04-19 | 2015-08-12 | 吉林大学 | High-yield Marasmius androsaceus mutant strain and cultivation method |
Non-Patent Citations (3)
| Title |
|---|
| WUHENG39: "安络痛片", 《WWW.DOC88.COM/P-97036841226.HTML》 * |
| 贾天柱等: "《中药炮制化学》", 31 October 2015, 上海科学技术出版社 * |
| 陈士瑜等: "《菇菌栽培手册》", 28 February 2003, 科学技术文献出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108452287A (en) * | 2018-06-20 | 2018-08-28 | 禹州市中瑞农业园林有限公司 | A kind of Chinese medicine package and preparation method for anti-rheumatism treating |
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Application publication date: 20170919 |