CN111905015A

CN111905015A - Traditional Chinese medicine preparation for preventing turtle parotitis and perforation disease and preparation method thereof

Info

Publication number: CN111905015A
Application number: CN202010826770.7A
Authority: CN
Inventors: 侯倩女; 戴利国; 王佳卉; 宋俊彦; 王佳珺
Original assignee: Hangzhou Baimahu Sightseeing Agriculture Co ltd
Current assignee: Hangzhou Baimahu Sightseeing Agriculture Co ltd
Priority date: 2020-08-17
Filing date: 2020-08-17
Publication date: 2020-11-10

Abstract

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine preparation for preventing parotitis and perforation disease of soft-shelled turtles, which is prepared from the following traditional Chinese medicine raw materials, by weight, 0.6-2 parts of cassia twig, 1-4 parts of astragalus membranaceus, 0.6-3 parts of scutellaria baicalensis, 0.5-2 parts of coptis chinensis, 2-5 parts of dandelion, 0.6-2 parts of radix paeoniae alba, 0.5-3 parts of wrinkled gianthyssop, 0.5-3 parts of eupatorium, 0.5-2 parts of mangnolia officinalis (flower), 1-3 parts of endothelium corneum gigeriae galli, 1-3 parts of poria cocos, 2-5 parts of medicated leaven, 1-4 parts of adenophora stricta, 0.5-2 parts of radix sophorae flavescentis, 0.5-2 parts of gallnut, 0.5-1.5 parts of dried orange. The soft-shelled turtle feed is prepared by baking, curing and sterilizing, finely grinding into powder according to the principle of monarch, minister, assistant and guide collocation, then mixing with lactobacillus for fermentation, mixing with a feed and feeding, and can achieve the purpose of preventing parotitis and perforation diseases of the soft-shelled turtle.

Description

Traditional Chinese medicine preparation for preventing turtle parotitis and perforation disease and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine preparation for preventing turtle parotitis and perforation disease and a preparation method thereof.

Background

The turtle parotitis is also called turtle parotitis, turtle hemorrhagic septicemia and turtle hemorrhagic disease and is caused by comprehensive infection of various bacteria, viruses and the like. The bacteria include aeromonas hydrophila, aeromonas sobria and the like, and the viruses include vibrio reovirus-like viruses, faecal adenovirus and the like. These pathogens infect the gill tissue through the injured body surface, produce enterotoxins and hemolysins, destroy the gastrointestinal wall into other tissue organs, and cause extensive systemic tissue organ infection and necrosis. The parotitis of the soft-shelled turtle is characterized in that the soft-shelled turtle is full-blown, neck swelling is serious, the soft-shelled turtle cannot breathe, dorsal concha and abdominal concha have punctate or plaque bleeding, blood foam flows out of mouth and nose, parotid gray fester, abdominal cavity and thoracic cavity have blood clots or parotid are red, and some small intestines have water-sample congestion and some have no congestion. The onset of the disease is characterized by slow response, head-back rising, mouth-nose water spraying and upright water-beating walking on the water surface. The turtle has the largest harm to parotitis, the strongest infectivity and the fastest death. The epidemic season is 6-9 months, and the disease is most serious when the water temperature is 25-30 ℃. Once the disease is not treated in time, the mortality rate reaches more than 60 percent.

The perforation disease of soft-shelled turtles (soft-shelled turtles) is mainly caused by various bacteria such as aeromonas hydrophila, proteus vulgaris, pneumonic burbacter xylinum, alcaligenes and the like. In the early stage of onset, the young soft-shelled turtles are sluggish in movement and the appetite is reduced. The dorsoventral concha, the skirt and the limb base of the diseased turtle have a plurality of white spots or white spots, even perforation, and the peak of the epidemic disease is 6-9 months. The main causes include external causes and internal causes, the external causes are pathogenic bacteria widely distributed in water, the water quality is easy to deteriorate in summer heat weather, and the turtle (soft-shelled turtle) inhabits the living habit and easily abrades the skin to make the pathogenic bacteria invade the organism. The internal reason is that the turtle (soft-shelled turtle) has increased food intake in the season, which is easy to cause the aggravation of gastrointestinal burden and is not easy to digest, and the intestinal flora is easy to cause imbalance, and the organism immunity is reduced and is easy to be infected by pathogenic bacteria.

The traditional Chinese medicine is based on the nature, the human body is based on the nature, the animal is related to the human body, and the theory of traditional Chinese medicine is applied to the animal. According to the theory of traditional Chinese medicine, the maintenance of the life process and the nutrients such as essence, qi, blood and body fluids are all dependent on the food essence generated by the transportation and transformation of the spleen (stomach). The spleen and stomach qi rise and fall in coordination to complete digestion of food and drink and absorption and transportation of food essence. The spleen is in the middle energizer and is the pivotal point for the transportation and transformation of water, so the spleen qi is healthy and healthy, the body fluids are fully transformed and distributed normally, and the viscera, body constituents, sense organs and orifices are nourished. The spleen pertains to earth and corresponds to the liver in the long summer. In summer, the climate is hot, rain is more, the weather is downward, the moisture rises, and the dampness is heat-steaming. Although dampness in summer is mainly generated, the spleen prefers dryness and dislikes dampness, and too much dampness can reverse the spleen and make it unable to move. Therefore, the spleen is weak in summer and autumn, which is likely to be affected by damp injury, and many damp diseases are caused by this. When it is in summer, dampness is accompanied by heat, and the heat and dampness are mixed to each other to cause disease. When the soft-shelled turtle grows in water and is susceptible to damp and heat, spleen function is reduced, food digestion, absorption of fine substances, transmission and distribution can be affected, and diseases such as inappetence, abdominal distension, emaciation and insufficient generation of essence, qi and blood occur. The lung is the son of the spleen, which joins the skin in the body, which is the exterior of the body, and has the functions of defending exogenous pathogens, regulating the metabolism of body fluids and body temperature, and assisting respiration. When the spleen fails to transport and transport, it will lead to the insufficiency of body fluids or failure of the spleen to transport the fluids to the heart and lung. In addition, the lung qi dispersing function of the mother and son is decreased, and the body fluid cannot be transported to all orifices of the head and face, and reaches the skin and hair muscle striae externally, the lung is in the nose, and the throat is the door of the lung, so that diseases of the throat and the head and face, such as parotitis and large neck disease, are easy to occur; the lung qi is descending in function, and the defensive qi is obstructed and can not be transported to the skin and hair, and various diseases such as skin rot and perforation are easily caused after the function of defending exogenous pathogenic factors is lost.

Disclosure of Invention

The invention provides a traditional Chinese medicine preparation for preventing the parotitis and the perforation disease of soft-shelled turtles, which is prepared by starting from prevention and improving the autoimmunity and the disease resistance of the soft-shelled turtles, mainly aims at strengthening the body resistance and achieves the aim of eliminating evil, and can generate considerable economic benefit, and a preparation method thereof.

In order to achieve the purpose, the invention adopts the following technical scheme: a Chinese medicinal preparation for preventing parotitis and perforation of soft-shelled turtles is prepared from (by weight parts) ramulus Cinnamomi 0.6-2, radix astragali 1-4, Scutellariae radix 0.6-3, Coptidis rhizoma 0.5-2, herba Taraxaci 2-5, radix Paeoniae alba 0.6-2, herba Agastaches 0.5-3, herba Eupatorii 0.5-3, cortex Magnolia officinalis (flower) 0.5-2, endothelium corneum Gigeriae Galli 1-3, Poria 1-3, Massa Medicata Fermentata 2-5, radix Adenophorae 1-4, radix Sophorae Flavescentis 0.5-2, Galla chinensis 0.5-2, pericarpium Citri Tangerinae 0.5-1.5, Sargassum 1-3, and Ganoderma 1-3. The weight parts of the medicine in the scheme can be unit weights of grams, ten grams and the like, and the grams of the medicine can be reduced or enlarged in an equal ratio in practical use.

In the scheme, the astragalus root is used for tonifying qi and lifting yang, the cassia twig is used for warming and dredging channels and collaterals, and assisting yang and regulating qi, and is good at ventilating yang and qi in defense system, and regulating nutrient and blood in skin and surface, and the astragalus root and the cassia twig are used as monarch drugs for resisting exogenous pathogenic factors. Radix Paeoniae alba has effects of nourishing blood, regulating menstruation, astringing yin, arresting sweating, softening liver, relieving pain, suppressing liver yang, and invigorating qi, and can be used with ramulus Cinnamomi for preventing excessive diffusion of ramulus Cinnamomi; in summer, the temperature is high, the soft-shelled turtles (soft-shelled turtles) are in water again, the moisture is heavy, the internal heat is easy to generate, and the dandelion is used for clearing heat, removing toxicity and promoting diuresis; the scutellaria and the coptis are used as ministerial drugs for clearing heat, purging fire and removing toxicity. Agastache rugosus can be used for eliminating dampness with aromatics, regulating the middle warmer and relieving vomiting, relieving exterior syndrome and relieving summer-heat; herba Eupatorii has effects of eliminating dampness with aromatics, activating spleen, stimulating appetite, relieving exterior syndrome, and clearing summer-heat; the magnolia bark (flower) has the effects of eliminating dampness and phlegm, descending qi and relieving fullness, and the combination of the three can improve the effect of relieving summer-heat, and can also prevent the spleen from losing transportation and transformation due to damp-heat and prevent gastrointestinal distention and inappetence caused by water-damp internal stagnation. The root of straight ladybell has the effects of nourishing yin, clearing away the lung-heat, tonifying stomach and promoting the production of body fluid, and also can prevent the consumption of body fluid caused by excessive dampness-drying medicines; the endothelium corneum Gigeriae Galli has strong effects of resolving food stagnation, invigorating spleen and stomach, and preventing food stagnation caused by eating of Amyda sinensis (soft-shelled turtle); liu Qu has the actions of resolving food stagnation, harmonizing stomach and regulating middle energizer. The combination of Ji Nei jin and Liu Qu can aggravate the action of promoting digestion and prevent indigestion, abdominal distention, poor appetite and anorexia. Poria cocos, Poria cocos. The dried orange peel can regulate qi and invigorate the spleen, and prevent abdominal distension and pain caused by qi stagnation of spleen and stomach. The sophora flavescens has the effects of clearing heat and drying dampness, killing parasites and promoting urination; the gallnut has the effects of astringing lung and reducing fire, astringing intestine and stopping diarrhea, arresting sweating, stopping bleeding, and astringing dampness and healing sores, and the gallnut prevents bacteria and parasites in water from being eaten into the body and attached to the body surface to cause pathological changes. The seaweed has the functions of softening hard masses, eliminating phlegm, inducing diuresis and relieving swelling, is rich in polysaccharide, contains calcium, phosphorus and magnesium, not only improves the immunity of the soft-shelled turtle, but also can be used as a food for the soft-shelled turtle. Herba Agastaches, herba Eupatorii, cortex Magnolia officinalis (flower), radix Adenophorae, endothelium corneum Gigeriae Galli, Massa Medicata Fermentata, Poria, pericarpium Citri Tangerinae, radix Sophorae Flavescentis, Galla chinensis, and Sargassum as adjuvant drugs. The lucid ganoderma has the effects of tonifying spleen and soothing nerves, is rich in polysaccharide, and is used as a messenger medicine to improve the immunity of the organism. After the lactobacillus is fermented, the lactobacillus can be absorbed by the organism more easily, the efficacy is more obvious, the qi is invigorated to the spleen, the earth is cultivated to generate the golden, the lactobacillus can effectively inhibit the growth of harmful bacteria, the poison of the toxin generated by the harmful bacteria in the intestinal tract to the whole organism is reduced, the lactobacillus has the functions of protecting the liver, enhancing the detoxification and toxin expelling of the liver, and the immunity of the organism is also improved.

Preferably, the granularity of the medicinal powder is 800 meshes.

A preparation method of a traditional Chinese medicine preparation for preventing turtle parotitis and perforation disease comprises the following steps:

1) selecting raw material tablets, and weighing the required raw material parts according to the raw material weight ratio;

2) putting the raw material tablets into a vacuum drying oven, and drying at 100 ℃ and under the vacuum degree of-0.1 Mpa for 30 minutes;

3) after the drying is finished, the raw material tablets are naturally cooled and ground into ultrafine powder by a 200-mesh 1000-mesh ultrafine grinder, and the size of the powder is 800 meshes;

4) weighing the superfine powder according to the required treatment amount, soaking the superfine powder in purified water for 20 minutes, boiling the superfine powder at 100 ℃, and then boiling the superfine powder for 30 minutes with soft fire;

5) weighing a lactic acid bacteria culture medium, uniformly mixing with purified water, sterilizing at high pressure, completely mixing the sterilized culture medium and the boiled traditional Chinese medicine liquid, naturally cooling to 40 ℃, inoculating a mixed lactic acid bacteria strain for fermentation, and fermenting for 24 hours at 40 ℃;

6) and after fermentation is finished, feeding the fermented feed according to the proportion and the feed mixture.

The formula of the scheme is obtained by a large amount of groping and summarizing experiences, all the traditional Chinese medicine materials are selected, the drug resistance and the drug residue of chemical agents are avoided, the environment is protected, the turtle is safe to eat, and the turtle can be prevented from being sick from entering the mouth; the formula of the preparation is prepared into powder by baking, curing and sterilizing, finely grinding according to the principle of monarch, minister, assistant and guide collocation, then mixing and feeding after fermenting by mixed lactic acid bacteria, so that the purpose of preventing parotitis and perforation diseases of the soft-shelled turtle can be achieved, the preparation has the characteristics of obvious effect and low cost, the soft-shelled turtle using the preparation has no antibiotics, belongs to ecological soft-shelled turtles, and the safety of consumers eating the soft-shelled turtles is guaranteed.

Therefore, the invention has the following beneficial effects: the Chinese medicinal composition has the advantages of strong pertinence, scientific compatibility, good use effect, guarantee of edible safety of human beings and considerable economic benefit.

Detailed Description

Embodiment 1, a Chinese medicinal preparation for preventing parotitis and perforation of soft-shelled turtles, which is a medicinal powder prepared from the following Chinese medicinal raw materials, by weight, 0.6 part of cassia twig, 4 parts of astragalus membranaceus, 0.5 part of scutellaria baicalensis, 1.5 parts of coptis chinensis, 3 parts of dandelion, 0.6 part of radix paeoniae alba, 1 part of agastache rugosus, 3 parts of eupatorium fortunei, 2 parts of magnolia officinalis flowers, 1 part of endothelium corneum gigeriae galli, 3 parts of poria cocos, 3 parts of medicated leaven, 1 part of adenophora stricta, 0.5 part of radix sophorae flavescentis, 2 parts of gallnut, 0.5 part of dried orange peel.

Embodiment 2, a Chinese medicinal preparation for preventing parotitis and perforation of soft-shelled turtles, which is a medicinal powder prepared from the following Chinese medicinal raw materials, by weight, 1 part of cassia twig, 3 parts of astragalus membranaceus, 1.2 parts of scutellaria baicalensis, 1 part of coptis chinensis, 2 parts of dandelion, 1 part of white peony root, 2 parts of wrinkled gianthyssop, 2 parts of eupatorium, 1 part of magnolia officinalis flower, 2 parts of endothelium corneum gigeriae galli, 1 part of poria cocos, 4 parts of medicated leaven, 2 parts of adenophora stricta, 1 part of sophora flavescens, 1 part of gallnut, 1 part of dried orange peel, 2 parts of.

Embodiment 3, a Chinese medicinal preparation for preventing parotitis and perforation of soft-shelled turtles, which is a medicinal powder prepared from the following Chinese medicinal raw materials, by weight, 1.5 parts of cassia twig, 2 parts of astragalus membranaceus, 2 parts of scutellaria baicalensis, 0.5 part of coptis chinensis, 4 parts of dandelion, 1.5 parts of white peony root, 3 parts of wrinkled gianthyssop herb, 1 part of eupatorium, 0.5 part of magnolia officinalis flower, 3 parts of endothelium corneum gigeriae galli, 2 parts of poria cocos, 2 parts of medicated leaven, 3 parts of adenophora stricta, 1.5 parts of sophora flavescens, 1.5 parts of gallnut, 1.2 parts of dried orange peel, 1.5 parts.

Embodiment 4, a Chinese medicinal preparation for preventing parotitis and perforation of soft-shelled turtles, which is a medicinal powder prepared from the following Chinese medicinal raw materials, by weight, 2 parts of cassia twig, 1 part of astragalus membranaceus, 3 parts of scutellaria baicalensis, 2 parts of coptis chinensis, 5 parts of dandelion, 2 parts of white peony root, 0.5 part of wrinkled gianthyssop herb, 0.5 part of eupatorium, 1.5 parts of magnolia officinalis flower, 1.5 parts of endothelium corneum gigeriae galli, 1.5 parts of poria cocos, 5 parts of medicated leaven, 4 parts of adenophora stricta, 2 parts of sophora flavescens, 0.5 part of gallnut, 1.5 parts of dried orange peel, 1 part of seaweed.

The specific implementation process comprises the following manufacturing steps:

In the turtle farm, the above-prepared preparation and feed are mixed and administered to a place where there are cases, and the mixture is administered for treatment, and in the other places, the preparation and feed are mixed and administered for prevention in a dose for prevention.

In a turtle cultivation base with one thousand mu area, 90 greenhouses and 4 big ponds in the first year are fed with the mixture of the traditional Chinese medicine formula for prevention, and the disease and death of the turtles (turtles) are avoided twice a day until the turtles (turtles) are hibernated. In addition, 10 greenhouses are fed with lactobacillus mixed with the feed, 3 greenhouses have parotitis in the middle and last ten days of 7 months and have perforation conditions of different degrees, and 3000 turtles die together after being treated by traditional Chinese medicines for one week immediately. Big neck and skin perforation diseases appear in 6 greenhouses, and 6000 turtles die after being treated by the perforation disease traditional Chinese medicine for one week. Then, the 10 greenhouses are all fed with the preventing traditional Chinese medicine formula mixing materials, and diseases and death do not occur. All greenhouses and outer ponds are completely fed with the traditional Chinese medicine formula mixed materials in 5-9 months from the second year, parotitis and perforation diseases are not found, the skin of the cultured turtles is glossy, skirt edges are thick, claw tips are shiny, limbs are thick, abdomen is white and red, mobility is strong, the selling price of the turtles is one time higher than that of other turtles in the market, and the turtles bred at present are basically purchased by high-grade hotels and patients with liver cancer diseases.

Claims

1. A traditional Chinese medicine preparation for preventing parotitis and perforation of soft-shelled turtles is characterized by being medicinal powder prepared from the following traditional Chinese medicine raw materials, 0.6-2 parts of cassia twig, 1-4 parts of astragalus membranaceus, 0.6-3 parts of scutellaria baicalensis, 0.5-2 parts of coptis chinensis, 2-5 parts of dandelion, 0.6-2 parts of white paeony root, 0.5-3 parts of wrinkled gianthyssop, 0.5-3 parts of fortune eupatorium herb, 0.5-2 parts of mangnolia officinalis (flower), 1-3 parts of chicken's gizzard-membrane, 1-3 parts of poria cocos, 2-5 parts of medicated leaven, 1-4 parts of adenophora elata, 0.5-2 parts of radix sophorae flavescentis, 0.5-2 parts of gallnut, 0.5-1.5 parts of dried orange peel, 1-3 parts of seaweed and.

2. The traditional Chinese medicine preparation for preventing parotitis and perforation of soft-shelled turtles as claimed in claim 1, wherein the preparation comprises, by weight, 0.6 part of cassia twig, 4 parts of astragalus membranaceus, 0.5 part of scutellaria baicalensis, 1.5 parts of coptis chinensis, 3 parts of dandelion, 0.6 part of radix paeoniae alba, 1 part of wrinkled gianthyssop, 3 parts of eupatorium, 2 parts of magnolia officinalis flower, 1 part of endothelium corneum gigeriae galli, 3 parts of poria cocos, 3 parts of medicated leaven, 1 part of adenophora stricta, 0.5 part of sophora flavescens, 2 parts of gallnut, 0.5 part of dried orange peel, 3 parts of seaweed and 1.

3. The traditional Chinese medicine preparation for preventing parotitis and perforation of soft-shelled turtles as claimed in claim 1, wherein the preparation comprises, by weight, 1 part of cassia twig, 3 parts of astragalus membranaceus, 1.2 parts of scutellaria baicalensis, 1 part of coptis chinensis, 2 parts of dandelion, 1 part of white peony root, 2 parts of agastache rugosus, 2 parts of eupatorium, 1 part of magnolia officinalis flower, 2 parts of endothelium corneum gigeriae galli, 1 part of poria cocos, 4 parts of medicated leaven, 2 parts of adenophora stricta, 1 part of sophora flavescens, 1 part of gallnut, 1 part of dried orange peel, 2 parts of seaweed and 2 parts of.

4. The traditional Chinese medicine preparation for preventing parotitis and perforation of soft-shelled turtles as claimed in claim 1, wherein the preparation comprises, by weight, 1.5 parts of cassia twig, 2 parts of astragalus membranaceus, 2 parts of scutellaria baicalensis, 0.5 part of coptis chinensis, 4 parts of dandelion, 1.5 parts of white peony root, 3 parts of wrinkled gianthyssop, 1 part of eupatorium, 0.5 part of magnolia officinalis flower, 3 parts of endothelium corneum gigeriae galli, 2 parts of poria cocos, 2 parts of medicated leaven, 3 parts of adenophora stricta, 1.5 parts of sophora flavescens, 1.5 parts of gallnut, 1.2 parts of dried orange peel, 1.5 parts of seaweed and 3.

5. The traditional Chinese medicine preparation for preventing parotitis and perforation of soft-shelled turtles as claimed in claim 1, wherein the preparation comprises, by weight, 2 parts of cassia twig, 1 part of astragalus membranaceus, 3 parts of scutellaria baicalensis, 2 parts of coptis chinensis, 5 parts of dandelion, 2 parts of radix paeoniae alba, 0.5 part of agastache rugosus, 0.5 part of eupatorium, 1.5 parts of magnolia officinalis flowers, 1.5 parts of endothelium corneum gigeriae galli, 1.5 parts of poria cocos, 5 parts of medicated leaven, 4 parts of adenophora stricta, 2 parts of radix sophorae flavescentis, 1.5 parts of dried orange peel, 1 part of seaweed and 2.5 parts.

6. The traditional Chinese medicine preparation for preventing parotitis and perforation of soft-shelled turtles as claimed in claim 1, wherein the particle size of the medicinal powder is 800 meshes.

7. The preparation method of the traditional Chinese medicine preparation for preventing turtle parotitis and perforation disease as claimed in any one of claims 1 to 5, comprising the following steps:

4) weighing the superfine powder according to the required treatment amount, soaking the superfine powder in purified water for 20 minutes,

boiling at 100 deg.C, and decocting with slow fire for 30 min;