CN107158251A - 一种中药消毒液及其制备方法 - Google Patents

一种中药消毒液及其制备方法 Download PDF

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CN107158251A
CN107158251A CN201710563376.7A CN201710563376A CN107158251A CN 107158251 A CN107158251 A CN 107158251A CN 201710563376 A CN201710563376 A CN 201710563376A CN 107158251 A CN107158251 A CN 107158251A
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chinese medicine
traditional chinese
medicine disinfectant
raw material
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张安育
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Hefei Huagai Biotechnology Co Ltd
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Hefei Huagai Biotechnology Co Ltd
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Abstract

本发明提供一种中药消毒液及其制备方法,涉及消毒液领域,中药消毒液包括以下重量份的原料:荜茇、密陀僧、石斛、蜂毒、油柑叶、黄根、三白草、秦皮、樟树叶、燕子尾、韶子、青叶丹、粳谷奴、菊苣、番泻叶、白屈菜、芦荟、五倍子、地丁、金银花、蛇床子和艾叶;制备方法包括以下步骤:(1)称取原料、(2)制得提取液和混合粉末、(3)混合。本发明解决了现有消毒液存在着对人体伤口以及皮肤有刺激性,甚至会引起人体过敏反应的问题。

Description

一种中药消毒液及其制备方法
技术领域
本发明属于消毒液领域,具体涉及一种中药消毒液及其制备方法。
背景技术
医疗机构进行医学检验时,检验系统的细菌群系应减少到最低限度,这便对医护人员本身以及检验所需的检验用具进行全方位的彻底的消毒,消除一系列的细菌以及病原菌例如金黄色葡萄球菌、大肠杆菌、伤寒沙门菌、绿脓假单胞菌、普通变形杆菌等,为检验系统提供良好的环境。
检验科作为医院检验化验的科室,经常会对一些患者提取标本进行检验,而检验工作需要在无菌条件下进行,以防止细菌、真菌以及病毒等混入检验标本,从而影响检验效果,使检验结果不精确,而检验所使用的杀菌消炎药物如碘酒、酒精、碘伏等大多对人体伤口以及皮肤有刺激性,有的甚至会引起过敏反应,甚至会引发皮炎和湿疹等皮肤疾病。此外,医疗环境的消毒对于检验工作也具有重要的意义。
为此,寻找一种安全、有效且无毒副作用的消毒液对于检验科各项检验工作将具有重要意义。
发明内容
为了解决现有消毒液存在着对人体伤口以及皮肤有刺激性,甚至会引起人体过敏反应的问题,本发明的目的是提供一种中药消毒液及其制备方法,制得的中药消毒液具有杀菌能力强、作用速度快、稳定性强、对人体皮肤无刺激、易溶于水、用后无残留、安全无毒副作用和可广泛应用于检验科人员皮肤、医疗器械以及医疗场所等的消毒的优点。
本发明提供了如下的技术方案:
一种中药消毒液,包括以下重量份数的原料:荜茇36-50份、密陀僧36-50份、石斛35-49份、蜂毒35-47份、油柑叶30-50份、黄根26-46份、三白草26-46份、秦皮26-44份、樟树叶22-38份、燕子尾22-38份、韶子20-30份、青叶丹16-34份、粳谷奴18-34份、菊苣15-31份、番泻叶13-27份、白屈菜12-24份、芦荟11-19份、五倍子21-39份、地丁16-28份、金银花13-25份、蛇床子17-27份和艾叶15-27份。
优选地,包括以下重量份的原料:荜茇43份、密陀僧43份、石斛42份、蜂毒41份、油柑叶40份、黄根26-46份、三白草26-46份、秦皮26-44份、樟树叶22-38份、燕子尾22-38份、韶子20-30份、青叶丹16-34份、粳谷奴18-34份、菊苣15-31份、番泻叶13-27份、白屈菜12-24份、芦荟11-19份、五倍子21-39份、地丁16-28份、金银花13-25份、蛇床子17-27份和艾叶15-27份。
优选地,所述中药消毒液的原料还包括重量份数为14-22份的甘草,甘草对金黄色葡萄球菌、结核杆菌、大肠杆菌和阿米巴原虫均有抑制作用。
优选地,所述中药消毒液的原料还包括重量份数为13-25份的黄连,黄连对链球菌、金黄色葡萄球菌、淋球菌和弗氏、志贺氏痢疾杆菌均有抗菌作用,并有增强白血球吞噬作用,对结核杆菌也有抑制作用。
优选地,所述中药消毒液的原料还包括重量份数为16-24份的白头翁,白头翁对金黄色葡萄球菌、绿脓杆菌、炭疽杆菌、伤寒杆菌、甲型链球菌和乙型链球菌均具有明显的抑制作用。
优选地,所述中药消毒液的原料还包括重量份数为11-21份的紫草,紫草对大肠埃希菌、伤寒杆菌、痢疾杆菌、金黄色葡萄球菌和绿脓杆菌均有抑制作用。
优选地,所述中药消毒液的原料还包括重量份数为8-14份的苦参,苦参对白色链球菌有抑制作用。
一种中药消毒液的制备方法,包括以下步骤:
(1)按照中药消毒液的原料重量份数称取原料;
(2)取荜茇、石斛、蜂毒、油柑叶、秦皮、韶子和番泻叶去杂质洗净,置于容器内,加入8-10倍量的蒸馏水浸泡4-6h后,煮沸3-4h,得到第一次提取液;再次加入5-7倍量蒸馏水,煮沸2-3h,得到第二次提取液;最后,加入2-4倍量蒸馏水,加热煮沸1-2h,得到第三次提取液;合并三次提取液,过滤,得到滤液;
(3)取密陀僧和粳谷奴去杂质,微波烘干后置于研钵内研末,过200目细粉,得到混合粉末;
(4)取黄根、三白草、燕子尾、青叶丹和菊苣去杂质洗净,置于容器内,加入5倍量的80%的乙醇溶液浸泡2-3h,加热提取5-6h后,回收乙醇,滤过,得到滤液;
(5)取樟树叶、白屈菜和其他剩余原料去杂质,绞碎,加入12-16倍量的蒸馏水,搅拌均匀过滤,得到滤液;
(6)将上述步骤(2)中滤液、步骤(3)中混合粉末、步骤(4)中滤液和步骤(5)中滤液混合,制成中药消毒液。
本发明的有益效果是:
1、本发明制得的中药消毒液具有杀菌能力强、作用速度快、稳定性强、对人体皮肤无刺激、易溶于水、用后无残留、安全无毒副作用和可广泛应用于检验科人员皮肤、医疗器械以及医疗场所等的消毒的优点。
2、本发明中所述中药消毒液的原料还包括重量份数为14-22份的甘草,甘草对金黄色葡萄球菌、结核杆菌、大肠杆菌和阿米巴原虫均有抑制作用。
3、本发明中所述中药消毒液的原料还包括重量份数为13-25份的黄连,黄连对链球菌、金黄色葡萄球菌、淋球菌和弗氏、志贺氏痢疾杆菌均有抗菌作用,并有增强白血球吞噬作用,对结核杆菌也有抑制作用。
4、本发明中所述中药消毒液的原料还包括重量份数为16-24份的白头翁,白头翁对金黄色葡萄球菌、绿脓杆菌、炭疽杆菌、伤寒杆菌、甲型链球菌和乙型链球菌均具有明显的抑制作用。
5、本发明中所述中药消毒液的原料还包括重量份数为11-21份的紫草,紫草对大肠埃希菌、伤寒杆菌、痢疾杆菌、金黄色葡萄球菌和绿脓杆菌均有抑制作用。
6、本发明中所述中药消毒液的原料还包括重量份数为8-14份的苦参,苦参对白色链球菌有抑制作用。
具体实施方式
实施例1
一种中药消毒液,包括以下重量份数的原料:荜茇43份、密陀僧43份、石斛42份、蜂毒41份、油柑叶40份、黄根26-46份、三白草26-46份、秦皮26-44份、樟树叶22-38份、燕子尾22-38份、韶子20-30份、青叶丹16-34份、粳谷奴18-34份、菊苣15-31份、番泻叶13-27份、白屈菜12-24份、芦荟11-19份、五倍子21-39份、地丁16-28份、金银花13-25份、蛇床子17-27份和艾叶15-27份。
中药消毒液的原料还包括重量份数为18份的甘草,甘草对金黄色葡萄球菌、结核杆菌、大肠杆菌和阿米巴原虫均有抑制作用。
中药消毒液的原料还包括重量份数为19份的黄连,黄连对链球菌、金黄色葡萄球菌、淋球菌和弗氏、志贺氏痢疾杆菌均有抗菌作用,并有增强白血球吞噬作用,对结核杆菌也有抑制作用。
中药消毒液的原料还包括重量份数为20份的白头翁,白头翁对金黄色葡萄球菌、绿脓杆菌、炭疽杆菌、伤寒杆菌、甲型链球菌和乙型链球菌均具有明显的抑制作用。
中药消毒液的原料还包括重量份数为16份的紫草,紫草对大肠埃希菌、伤寒杆菌、痢疾杆菌、金黄色葡萄球菌和绿脓杆菌均有抑制作用。
中药消毒液的原料还包括重量份数为11份的苦参,苦参对白色链球菌有抑制作用。
一种中药消毒液的制备方法,包括以下步骤:
(1)按照中药消毒液的原料重量份数称取原料;
(2)取荜茇、石斛、蜂毒、油柑叶、秦皮、韶子和番泻叶去杂质洗净,置于容器内,加入8-10倍量的蒸馏水浸泡4-6h后,煮沸3-4h,得到第一次提取液;再次加入5-7倍量蒸馏水,煮沸2-3h,得到第二次提取液;最后,加入2-4倍量蒸馏水,加热煮沸1-2h,得到第三次提取液;合并三次提取液,过滤,得到滤液;
(3)取密陀僧和粳谷奴去杂质,微波烘干后置于研钵内研末,过200目细粉,得到混合粉末;
(4)取黄根、三白草、燕子尾、青叶丹和菊苣去杂质洗净,置于容器内,加入5倍量的80%的乙醇溶液浸泡2-3h,加热提取5-6h后,回收乙醇,滤过,得到滤液;
(5)取樟树叶、白屈菜和其他剩余原料去杂质,绞碎,加入12-16倍量的蒸馏水,搅拌均匀过滤,得到滤液;
(6)将上述步骤(2)中滤液、步骤(3)中混合粉末、步骤(4)中滤液和步骤(5)中滤液混合,制成中药消毒液。
实施例2
一种中药消毒液,包括以下重量份数的原料:荜茇36份、密陀僧36份、石斛35份、蜂毒35份、油柑叶30份、黄根26份、三白草26份、秦皮26份、樟树叶22份、燕子尾22份、韶子20份、青叶丹16份、粳谷奴18份、菊苣15份、番泻叶13份、白屈菜12份、芦荟11份、五倍子21份、地丁16份、金银花13份、蛇床子17份和艾叶15份。
中药消毒液的原料还包括重量份数为14份的甘草,甘草对金黄色葡萄球菌、结核杆菌、大肠杆菌和阿米巴原虫均有抑制作用。
中药消毒液的原料还包括重量份数为13份的黄连,黄连对链球菌、金黄色葡萄球菌、淋球菌和弗氏、志贺氏痢疾杆菌均有抗菌作用,并有增强白血球吞噬作用,对结核杆菌也有抑制作用。
中药消毒液的原料还包括重量份数为16份的白头翁,白头翁对金黄色葡萄球菌、绿脓杆菌、炭疽杆菌、伤寒杆菌、甲型链球菌和乙型链球菌均具有明显的抑制作用。
中药消毒液的原料还包括重量份数为11份的紫草,紫草对大肠埃希菌、伤寒杆菌、痢疾杆菌、金黄色葡萄球菌和绿脓杆菌均有抑制作用。
中药消毒液的原料还包括重量份数为8份的苦参,苦参对白色链球菌有抑制作用。
一种中药消毒液的制备方法,包括以下步骤:
(1)按照中药消毒液的原料重量份数称取原料;
(2)取荜茇、石斛、蜂毒、油柑叶、秦皮、韶子和番泻叶去杂质洗净,置于容器内,加入8-10倍量的蒸馏水浸泡4-6h后,煮沸3-4h,得到第一次提取液;再次加入5-7倍量蒸馏水,煮沸2-3h,得到第二次提取液;最后,加入2-4倍量蒸馏水,加热煮沸1-2h,得到第三次提取液;合并三次提取液,过滤,得到滤液;
(3)取密陀僧和粳谷奴去杂质,微波烘干后置于研钵内研末,过200目细粉,得到混合粉末;
(4)取黄根、三白草、燕子尾、青叶丹和菊苣去杂质洗净,置于容器内,加入5倍量的80%的乙醇溶液浸泡2-3h,加热提取5-6h后,回收乙醇,滤过,得到滤液;
(5)取樟树叶、白屈菜和其他剩余原料去杂质,绞碎,加入12-16倍量的蒸馏水,搅拌均匀过滤,得到滤液;
(6)将上述步骤(2)中滤液、步骤(3)中混合粉末、步骤(4)中滤液和步骤(5)中滤液混合,制成中药消毒液。
实施例3
一种中药消毒液,包括以下重量份数的原料:荜茇50份、密陀僧50份、石斛49份、蜂毒47份、油柑叶50份、黄根46份、三白草46份、秦皮44份、樟树叶38份、燕子尾38份、韶子30份、青叶丹34份、粳谷奴34份、菊苣31份、番泻叶27份、白屈菜24份、芦荟19份、五倍子39份、地丁28份、金银花25份、蛇床子27份和艾叶27份。
中药消毒液的原料还包括重量份数为22份的甘草,甘草对金黄色葡萄球菌、结核杆菌、大肠杆菌和阿米巴原虫均有抑制作用。
中药消毒液的原料还包括重量份数为25份的黄连,黄连对链球菌、金黄色葡萄球菌、淋球菌和弗氏、志贺氏痢疾杆菌均有抗菌作用,并有增强白血球吞噬作用,对结核杆菌也有抑制作用。
中药消毒液的原料还包括重量份数为24份的白头翁,白头翁对金黄色葡萄球菌、绿脓杆菌、炭疽杆菌、伤寒杆菌、甲型链球菌和乙型链球菌均具有明显的抑制作用。
中药消毒液的原料还包括重量份数为21份的紫草,紫草对大肠埃希菌、伤寒杆菌、痢疾杆菌、金黄色葡萄球菌和绿脓杆菌均有抑制作用。
中药消毒液的原料还包括重量份数为14份的苦参,苦参对白色链球菌有抑制作用。
一种中药消毒液的制备方法,包括以下步骤:
(1)按照中药消毒液的原料重量份数称取原料;
(2)取荜茇、石斛、蜂毒、油柑叶、秦皮、韶子和番泻叶去杂质洗净,置于容器内,加入8-10倍量的蒸馏水浸泡4-6h后,煮沸3-4h,得到第一次提取液;再次加入5-7倍量蒸馏水,煮沸2-3h,得到第二次提取液;最后,加入2-4倍量蒸馏水,加热煮沸1-2h,得到第三次提取液;合并三次提取液,过滤,得到滤液;
(3)取密陀僧和粳谷奴去杂质,微波烘干后置于研钵内研末,过200目细粉,得到混合粉末;
(4)取黄根、三白草、燕子尾、青叶丹和菊苣去杂质洗净,置于容器内,加入5倍量的80%的乙醇溶液浸泡2-3h,加热提取5-6h后,回收乙醇,滤过,得到滤液;
(5)取樟树叶、白屈菜和其他剩余原料去杂质,绞碎,加入12-16倍量的蒸馏水,搅拌均匀过滤,得到滤液;
(6)将上述步骤(2)中滤液、步骤(3)中混合粉末、步骤(4)中滤液和步骤(5)中滤液混合,制成中药消毒液。
对比例
一种中药消毒液,包括以下重量份数的原料:荜茇43份、密陀僧43份、石斛42份、蜂毒41份、油柑叶40份、黄根26-46份、三白草26-46份、秦皮26-44份、樟树叶22-38份、燕子尾22-38份、韶子20-30份、青叶丹16-34份、粳谷奴18-34份、菊苣15-31份、番泻叶13-27份和白屈菜12-24份。
一种中药消毒液的制备方法,包括以下步骤:
(1)按照中药消毒液的原料重量份数称取原料;
(2)取荜茇、石斛、蜂毒、油柑叶、秦皮、韶子和番泻叶去杂质洗净,置于容器内,加入8-10倍量的蒸馏水浸泡4-6h后,煮沸3-4h,得到第一次提取液;再次加入5-7倍量蒸馏水,煮沸2-3h,得到第二次提取液;最后,加入2-4倍量蒸馏水,加热煮沸1-2h,得到第三次提取液;合并三次提取液,过滤,得到滤液;
(3)取密陀僧和粳谷奴去杂质,微波烘干后置于研钵内研末,过200目细粉,得到混合粉末;
(4)取黄根、三白草、燕子尾、青叶丹和菊苣去杂质洗净,置于容器内,加入5倍量的80%的乙醇溶液浸泡2-3h,加热提取5-6h后,回收乙醇,滤过,得到滤液;
(5)取樟树叶和白屈菜去杂质,绞碎,加入12-16倍量的蒸馏水,搅拌均匀过滤,得到滤液;
(6)将上述步骤(2)中滤液、步骤(3)中混合粉末、步骤(4)中滤液和步骤(5)中滤液混合,制成中药消毒液。
下面对本发明制得的中药消毒液与对比例中制得的中药消毒液进行抑菌实验:
1、实验菌种:挑选实验室具有代表性的菌种,金黄色葡萄球菌、白色念珠球菌和绿脓杆菌。
2、菌种培养基:营养琼脂培养基和营养肉汤培养基。
3、实验分类:抑菌实验分实验组和对照组,实验组选用本发明中的中药消毒液,对照组选用对比例中的中药消毒液。
4、具体实验步骤:
(1)菌液的制备:将上述三种菌种分别接种于三个琼脂培养基上,在37℃下培养36h,分别从上述琼脂培养基中挑取典型菌落分别接种于三个新鲜的营养肉汤培养基中,同温度下,培养24h,备用;
(2)消毒液选用:取本发明中药消毒液和对比例中的中药消毒液各45ml,分别置于稀释容器中,对其分别稀释30倍,将上述两种稀释液溶液分别分置于三个容器内,置于无菌条件下,备用;
(3)菌种分装与标记:将上述步骤(1)经营养肉汤培养24h的实验菌种用无菌的营养肉汤分别稀释50倍,每种菌种分装于两个培养皿中,分别标记对照组和实验组;
(4)杀菌:将上述步骤(2)所得的2g本发明中药消毒液的稀释溶液分别滴入实验组培养皿,2g对比例中的中药消毒液稀释溶液分别滴入对照组培养皿。
5、试验观察测量:对上述实验进行观察,观察三组菌种并测量菌种残留面积,并记录观察数据结果,测试结果如表1所示:
从表1数据比较可以看出,本发明的优点是:
本发明的中药消毒液的杀菌能力比对比例中的中药消毒液的杀菌能力要强的多。
以上所述仅为本发明的优选实施例而已,并不用于限制本发明,尽管参照前述实施例对本发明进行了详细的说明,对于本领域的技术人员来说,其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分技术特征进行等同替换,凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。

Claims (8)

1.一种中药消毒液,其特征在于,包括以下重量份数的原料:荜茇36-50份、密陀僧36-50份、石斛35-49份、蜂毒35-47份、油柑叶30-50份、黄根26-46份、三白草26-46份、秦皮26-44份、樟树叶22-38份、燕子尾22-38份、韶子20-30份、青叶丹16-34份、粳谷奴18-34份、菊苣15-31份、番泻叶13-27份、白屈菜12-24份、芦荟11-19份、五倍子21-39份、地丁16-28份、金银花13-25份、蛇床子17-27份和艾叶15-27份。
2.根据权利要求1所述的中药消毒液,其特征在于,包括以下重量份的原料:荜茇43份、密陀僧43份、石斛42份、蜂毒41份、油柑叶40份、黄根26-46份、三白草26-46份、秦皮26-44份、樟树叶22-38份、燕子尾22-38份、韶子20-30份、青叶丹16-34份、粳谷奴18-34份、菊苣15-31份、番泻叶13-27份、白屈菜12-24份、芦荟11-19份、五倍子21-39份、地丁16-28份、金银花13-25份、蛇床子17-27份和艾叶15-27份。
3.根据权利要求1所述的中药消毒液,其特征在于:所述中药消毒液的原料还包括重量份数为14-22份的甘草。
4.根据权利要求1所述的中药消毒液,其特征在于:所述中药消毒液的原料还包括重量份数为13-25份的黄连。
5.根据权利要求1所述的中药消毒液,其特征在于:所述中药消毒液的原料还包括重量份数为16-24份的白头翁。
6.根据权利要求1所述的中药消毒液,其特征在于:所述中药消毒液的原料还包括重量份数为11-21份的紫草。
7.根据权利要求1所述的中药消毒液,其特征在于:所述中药消毒液的原料还包括重量份数为8-14份的苦参。
8.一种如权利要求1—7任意一项所述的中药消毒液的制备方法,其特征在于,包括以下步骤:
(1)按照中药消毒液的原料重量份数称取原料;
(2)取荜茇、石斛、蜂毒、油柑叶、秦皮、韶子和番泻叶去杂质洗净,置于容器内,加入8-10倍量的蒸馏水浸泡4-6h后,煮沸3-4h,得到第一次提取液;再次加入5-7倍量蒸馏水,煮沸2-3h,得到第二次提取液;最后,加入2-4倍量蒸馏水,加热煮沸1-2h,得到第三次提取液;合并三次提取液,过滤,得到滤液;
(3)取密陀僧和粳谷奴去杂质,微波烘干后置于研钵内研末,过200目细粉,得到混合粉末;
(4)取黄根、三白草、燕子尾、青叶丹和菊苣去杂质洗净,置于容器内,加入5倍量的80%的乙醇溶液浸泡2-3h,加热提取5-6h后,回收乙醇,滤过,得到滤液;
(5)取樟树叶、白屈菜和其他剩余原料去杂质,绞碎,加入12-16倍量的蒸馏水,搅拌均匀过滤,得到滤液;
(6)将上述步骤(2)中滤液、步骤(3)中混合粉末、步骤(4)中滤液和步骤(5)中滤液混合,制成中药消毒液。
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CN107916574A (zh) * 2017-10-31 2018-04-17 南宁市致良行文化传播有限公司 一种孔雀羽毛的处理方法
CN108576082A (zh) * 2018-01-24 2018-09-28 合肥华盖生物科技有限公司 一种新型消毒液及其制备方法

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CN103768405A (zh) * 2014-01-19 2014-05-07 赵静 一种中药消毒液及制备方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107916574A (zh) * 2017-10-31 2018-04-17 南宁市致良行文化传播有限公司 一种孔雀羽毛的处理方法
CN108576082A (zh) * 2018-01-24 2018-09-28 合肥华盖生物科技有限公司 一种新型消毒液及其制备方法

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