CN107157826A - A kind of anti-oxidant antibacterial Face-protecting mask - Google Patents

Abstract

The invention provides the anti-oxidant antibacterial Face-protecting mask of one kind, this anti-oxidant antibacterial Face-protecting mask takes 0.2~2.8 part of dish extract, 3~17 parts of butanediol, 5~25 parts of propane diols, 1~5 part of cetostearyl alcohol, 0.01~0.1 part of Sodium Hyaluronate, 0.1~0.5 part of Aloe Vera Gel, 0.02~0.1 part of tocopherol, 0.1~0.5 part of xanthans, 0.1~0.3 part of carbomer, 0.01~0.05 part of allantoin, 0.1~0.5 part of Phenoxyethanol, 0.1~0.7 part of methyl hydroxybenzoate.The anti-oxidant antibacterial Face-protecting mask of the present invention not only has good inhibiting bacteria and diminishing inflammation and repairing effect, also with good antioxidant effect.

Description

A kind of anti-oxidant antibacterial Face-protecting mask

Technical field

The present invention relates to daily cosmetics field, and in particular to a kind of anti-oxidant antibacterial Face-protecting mask.

Background technology

The principle of facial mask, exactly using the of short duration time for being covered in face, is temporarily isolating air and the pollution in the external world, improves Skin temperature, the pore expansion of skin, promotes sweat gland secretion and metabolism, the oxygen content of skin is increased, facial mask is conducive to The moisture that skin is excluded in the product of epidermal cell metabolism and the oil substances of accumulation, facial mask penetrates into the angle of skin epidermis Matter layer, skin becomes soft, increase elasticity.

Existing expense dish is used for medicine or tea-drinking, and we have found by research and refering to documents and materials, Fei Caisuo Ingredients Biogenic alkali, amino acid, steroidal, saponin(e, phenolic acid and the Crassulaceae polysaccharide contained, these contents have very big exploitation valency Value, repairs to antibacterial, anti-oxidant has good curative effect and effect.

The content of the invention

It is an object of the invention to provide the anti-oxidant antibacterial Face-protecting mask of one kind, this anti-oxidant antibacterial Face-protecting mask is not only With good inhibiting bacteria and diminishing inflammation and repairing effect, also with good antioxidant effect.

To reach that the above-mentioned purpose present invention provides following technical scheme：

A kind of anti-oxidant antibacterial Face-protecting mask includes following components by weight：Take 0.2~2.8 part of dish extract, fourth 3~17 parts of glycol, 5~25 parts of propane diols, 1~5 part of cetostearyl alcohol, 0.01~0.1 part of Sodium Hyaluronate, Aloe Vera Gel 0.1~ 0.5 part, 0.02~0.1 part of tocopherol, 0.1~0.5 part of xanthans, 0.1~0.3 part of carbomer, 0.01~0.05 part of allantoin, 0.1~0.5 part of Phenoxyethanol, 0.1~0.7 part of methyl hydroxybenzoate.

Preferably, described anti-oxidant antibacterial Face-protecting mask includes following components by weight：Take dish extract 0.5~ 2.5 parts, 5~15 parts of butanediol, 7~23 parts of propane diols, 2~4 parts of cetostearyl alcohol, 0.02~0.08 part of Sodium Hyaluronate, reed 0.2~0.4 part of luxuriant growth glue, 0.02~0.08 part of tocopherol, 0.2~0.4 part of xanthans, 0.1~0.2 part of carbomer, allantoin 0.02~0.04 part, 0.2~0.4 part of Phenoxyethanol, 0.2~0.6 part of methyl hydroxybenzoate.

Optimally, described facial mask includes following components by weight：Take 2 parts of dish extract, 10 parts of butanediol, the third two 15 parts of alcohol, 3 parts of cetostearyl alcohol, 0.05 part of Sodium Hyaluronate, 0.3 part of Aloe Vera Gel, 0.05 part of tocopherol, 0.3 part of xanthans, card 0.2 part of ripple nurse, 0.03 part of allantoin, 0.3 part of Phenoxyethanol, 0.4 part of methyl hydroxybenzoate.

It is described expense dish extract preparation method be：To take dish clean dry, size-reduced machine crosses 40~60 mesh sieves after crushing, By solid-liquid ratio 1：(30~40) 50~70% ethanol are added and carries out ultrasonic extraction, extracted 3 times, 30~60min, is filtered every time, is closed And can obtain expense dish extract through concentration after filtrate.

A kind of preparation method of anti-oxidant antibacterial Face-protecting mask comprises the following steps：

(1) by propane diols, butanediol, cetostearyl alcohol, Sodium Hyaluronate, Aloe Vera Gel, tocopherol, xanthans, carbomer, Allantoin, Phenoxyethanol, methyl hydroxybenzoate, deionized water, add in agitated kettle and are heated to 75-80 DEG C, stirring and dissolving is complete；

(2) 45-55 DEG C is cooled to, addition takes dish extract, cooling discharging after stirring and dissolving is uniform.

Explained below is made to position raw material in the anti-oxidant antibacterial Face-protecting mask of the present invention：

Take dish extract：Take dish, Crassulaceae Sedum herbaceos perennial, root-like stock is short, thick stem is high up to 50 centimetres, Uprightly.Leaf alternate, leaf is solid, nearly keratin.Cyme is spent more, sepal meat, petal yellow, style jumping chisel shape.Seed is ellipse Circle, the flowering fruit bearing stage 6-9 months.Take cupreol energy stabilizing cell membrane structure in dish extract, keep the lipid of cell membrane not by mistake Oxidation is so as to cause functional structure obstacle；Stigmasterol can reduce lipid peroxidation in expense dish extract, increase activities of antioxidant enzymes, And then reach that remove free radical reduces effect of free radical generating rate simultaneously, substantially reduces free radical cumulative speed, says simultaneously It is bright that there is stronger antioxidation activity.The expression of its relevant enzyme that can suppress inflammatory factor induction simultaneously, and then reduce related scorching The release of disease material, reduces the intensity of inflammation；Quercetin can suppress the gene expression of inflammatory factor in expense dish extract, and then press down The increase of inflammatory factor processed, the intensity of final reduction inflammation performance, can suppress oxidase active, while also can directly remove freedom Base and chelant ion, and then suppress lipoprotein and DNA oxidative damage, and then membrane damage is reduced with nuclear damage to Skin Cell Influence；The myricetin taken in dish extract is similar with Quercetin, and myricetin can suppress inflammatory factor activity, and then reduce inflammation Jie Element generation, reaches the purpose for reducing inflammatory intensity；Crassulaceae polysaccharide compound in expense dish extract can reduce inflammation interleukin Activity, suppresses the intensity of inflammatory reaction indirectly, while can immune cell activated, enhancing related cell activities, raising region of interest Immunologic function, accelerate inflammation part disappear.Other Crassulaceae polysaccharide can also improve SOD activity, and increase body is removed freely The ability of base, can repair activities of antioxidant enzymes of the part by radiation effect, and then reach oxidation-resisting and caducity, Antiradiation injury Ability.

Compared with prior art, the method have the advantages that：

(1) sleep mask that main usage charges dish extract is formulated in the anti-oxidant antibacterial Face-protecting mask of the present invention, its Each component substances that middle expense dish contains can suppress inflammation well, resist radical damage.Wherein cupreol, stigmasterol, Mongolian oak Pi Su, myricetin function are similar, inflammation can be controlled and be limited from different perspectives, can adjust the immune flat of skin environment Weighing apparatus, it is to avoid inflammatory effect and the raw acne that happens suddenly.Quercetin is avoided that the accident with DNA plerosis is damaged with polysaccharide material simultaneously, simultaneously Also oxidation balance can be controlled in terms of oxidase active with activities of antioxidant enzymes two respectively, it is to avoid the generation of free radical and Cause cell ageing.Make the anti-oxidant antibacterial Face-protecting mask of the present invention that not only there is good inhibiting bacteria and diminishing inflammation and repairing effect, also have There is good antioxidant effect.

(2) the anti-oxidant antibacterial Face-protecting mask natural no stimulation of the present invention, is adapted to skin sensitivity crowd and uses.

Embodiment

Below in conjunction with specific embodiment, the present invention is further elaborated.The anti-oxidant antibacterial maintenance of the present invention of embodiment 1~5 Face pack prescription is shown in Table one

Table one

Described in embodiment 1~5 take dish extract preparation method be：To take dish clean dry, after size-reduced machine is crushed 60 mesh sieves are crossed, by solid-liquid ratio 1：40, which add 70% ethanol, carries out ultrasonic extraction, extracts 3 times, each 60min, filtering, merging filtrate It can obtain taking dish extract by concentration.

The preparation method of the antibacterial Face-protecting mask of antioxygen described in embodiment 1~5 comprises the following steps：

(1) by propane diols, butanediol, cetostearyl alcohol, Sodium Hyaluronate, Aloe Vera Gel, tocopherol, xanthans, carbomer, Allantoin, Phenoxyethanol, methyl hydroxybenzoate, deionized water, add in agitated kettle and are heated to 80 DEG C, stirring and dissolving is complete；

(2) 55 DEG C are cooled to, addition takes dish extract, cooling discharging after stirring and dissolving is uniform.

Comparative example 1

Difference with embodiment 1 is to add 0.1 part of expense dish extract, and other preparation conditions and method are same as Example 1.

Comparative example 2

Difference with embodiment 1 is to add 2.9 parts of expense dish extract, and other preparation conditions and method are same as Example 1.

Comparative example 3

Difference with embodiment 1 is not add expense dish extract, and other preparation conditions and method are same as Example 1.

Bacteriostasis efficacy is verified

This case chooses staphylococcus aureus and Escherichia coli and carries out antibacterial reality with reference to GB 15979-2002 appendix Cs 3 Test.Table two lists embodiment 1~6 of the simulation human body skin environmental treatment after 4 hours, comparative example 1~3 and claims tool on the market There is the antibacterial experiment result of the facial mask of good anti-oxidant antibacterial repairing effect as a control group.

Table two

Efficacy validation

According to the obtained anti-oxidant antibacterial facial mask and on the market repaired of above-described embodiment 1~6, the formula of comparative example 1~3 Claim with the good anti-oxidant antibacterial facial mask for repairing effect as commercially available group.Respectively to three groups of 15-60 Sui people, every group of 100 people, Control ten sections of facial masks of external application are simultaneously compared, and the trial period is five weeks, and experimental result is shown in Table three：

Table three

Improved by the visible pockmark reparation of embodiment 1~6 of table two, inflammation and the significant number of anti-acne effect is significantly more than contrast Example 1~3 and commercially available product, illustrate that the anti-oxidant antibacterial reparation facial mask of the present invention has significant pockmark reparation, inflammation to improve and anti-acne effect Really；The pockmark reparation of comparative example 3, inflammation improve and anti-acne improves significantly lower than other embodiment and comparative example, illustrate expense of the present invention Dish extract is principle active component；Comparative example 1,2 contrasts visible in the anti-oxidant antibacterial reparation facial mask of the present invention with embodiment 1 In, use the interval science of formula optimal.

The test (DPPH tests) of antioxidation

In order to examine the anti-oxidant antibacterial antioxygen for repairing facial mask prepared in comparative example 1-6 and comparative example 1-3 Change is acted on, and based on the change of the absorbance caused by the reduction as free radical DPPH, passes through comparative measurements DPPH (1,1- hexichol Base -2- picryls hydrazone (1,1-diphenyl-2-picrylhydrazyl)) antopxidation evaluates the anti-oxidant of these samples Activity.It is determined as the decline of the absorbance caused by the oxidation for suppressing DPPH, absorbance is tester compared with tester 50% when concentration be defined as effective anti-oxidant concentration.

Anti-oxidant antibacterial the reparation facial mask and positive control sample that 10 μ l are obtained in embodiment 1-6 and comparative example 1-3 Product are added in 190 μ l 100 μM of DPPH ethanol solution, to prepare reaction solution.Reaction solution is allowed in reaction at 37 DEG C 30 minutes, then determine absorbance under 540nm.Use the antioxidant watermiscible vitamin E of widely used synthesis (Trolox) as positive control.The DPPH analysis results of each material are shown in following table four.In table four, IC50 refers to inhale Luminosity declines sample concentration when 50%.

Table four

Sample	IC50(ppm)
		Watermiscible vitamin E	45
Embodiment 1	95
		Embodiment 2	80
Embodiment 3	76
		Embodiment 4	75
Embodiment 5	82
		Embodiment 6	83
Comparative example 1	30
		Comparative example 2	21
Comparative example 3	22

Experiment shows that inventive formulation has good antioxygenic property, the ability with very strong removing free radical.

Above example only illustrates embodiment of the present invention, does not have any formal limitation to the present invention；Appoint What is engaged in professional and technical personnel, all has the ability to make some changes using the technology contents disclosed or modifies, as equivalent The equivalent embodiment of change, according to the technology of the present invention essence, simply modification, equivalent variations and modification is carried out to the present invention, is belonged to In the range of technical solution of the present invention.

Claims (5)

1. a kind of anti-oxidant antibacterial Face-protecting mask, it is characterised in that the facial mask includes following components by weight：

Take 0.2~2.8 part of dish extract, 3~17 parts of butanediol, 5~25 parts of propane diols, 1~5 part of cetostearyl alcohol, hyalomitome Sour 0.01~0.1 part of sodium, 0.1~0.5 part of Aloe Vera Gel, 0.02~0.1 part of tocopherol, 0.1~0.5 part of xanthans, carbomer 0.1 ~0.3 part, 0.01~0.05 part of allantoin, 0.1~0.5 part of Phenoxyethanol, 0.1~0.7 part of methyl hydroxybenzoate.

2. the anti-oxidant antibacterial Face-protecting mask of one kind according to claim 1, it is characterised in that the facial mask is by weight Including following components：

Take 0.5~2.5 part of dish extract, 5~15 parts of butanediol, 7~23 parts of propane diols, 2~4 parts of cetostearyl alcohol, hyalomitome Sour 0.02~0.08 part of sodium, 0.2~0.4 part of Aloe Vera Gel, 0.02~0.08 part of tocopherol, 0.2~0.4 part of xanthans, carbomer 0.1~0.2 part, 0.02~0.04 part of allantoin, 0.2~0.4 part of Phenoxyethanol, 0.2~0.6 part of methyl hydroxybenzoate.

3. the anti-oxidant antibacterial Face-protecting mask of one kind according to claim 2, it is characterised in that the facial mask is by weight Including following components：

Take 2 parts of dish extract, 10 parts of butanediol, 15 parts of propane diols, 3 parts of cetostearyl alcohol, 0.05 part of Sodium Hyaluronate, Aloe Vera Gel 0.3 part, 0.05 part of tocopherol, 0.3 part of xanthans, 0.2 part of carbomer, 0.03 part of allantoin, 0.3 part of Phenoxyethanol, oxybenzene first 0.4 part of ester.

4. a kind of anti-oxidant antibacterial Face-protecting mask according to any one of claims 1 to 3, it is characterised in that described to take dish The preparation method of extract is：To take dish clean dry, size-reduced machine crosses 40~60 mesh sieves after crushing, by solid-liquid ratio 1：(30~ 40) 50~70% ethanol are added and carries out ultrasonic extraction, extracted 3 times, 30~60min, is filtered every time, is through concentration after merging filtrate It can obtain taking dish extract.

5. a kind of preparation method of the antibacterial Face-protecting mask of antioxygen as described in any one of Claims 1 to 4, it is characterised in that bag Include following steps：

(1) by propane diols, butanediol, cetostearyl alcohol, Sodium Hyaluronate, Aloe Vera Gel, tocopherol, xanthans, carbomer, allantois Element, Phenoxyethanol, methyl hydroxybenzoate, deionized water, add in agitated kettle and are heated to 75-80 DEG C, stirring and dissolving is complete；

(2) 45-55 DEG C is cooled to, addition takes dish extract, cooling discharging after stirring and dissolving is uniform.