CN107136510A - One kind improves immunity health food and preparation method thereof - Google Patents
One kind improves immunity health food and preparation method thereof Download PDFInfo
- Publication number
- CN107136510A CN107136510A CN201710563304.2A CN201710563304A CN107136510A CN 107136510 A CN107136510 A CN 107136510A CN 201710563304 A CN201710563304 A CN 201710563304A CN 107136510 A CN107136510 A CN 107136510A
- Authority
- CN
- China
- Prior art keywords
- parts
- red ginseng
- weight
- health food
- rehmannia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000036039 immunity Effects 0.000 title claims abstract description 28
- 235000013402 health food Nutrition 0.000 title claims abstract description 23
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 235000002789 Panax ginseng Nutrition 0.000 claims abstract description 34
- 239000000284 extract Substances 0.000 claims abstract description 30
- 241000405414 Rehmannia Species 0.000 claims abstract description 19
- 240000008397 Ganoderma lucidum Species 0.000 claims abstract description 18
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims abstract description 18
- 239000009636 Huang Qi Substances 0.000 claims abstract description 17
- 244000241838 Lycium barbarum Species 0.000 claims abstract description 17
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 17
- 239000002994 raw material Substances 0.000 claims abstract description 14
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 7
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 7
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 7
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 7
- 229920002472 Starch Polymers 0.000 claims abstract description 6
- 235000019698 starch Nutrition 0.000 claims abstract description 6
- 239000008107 starch Substances 0.000 claims abstract description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 15
- 241000208340 Araliaceae Species 0.000 claims description 11
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 11
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 11
- 235000008434 ginseng Nutrition 0.000 claims description 11
- 238000005469 granulation Methods 0.000 claims description 8
- 230000003179 granulation Effects 0.000 claims description 8
- 238000001035 drying Methods 0.000 claims description 6
- 235000013305 food Nutrition 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
- 235000005979 Citrus limon Nutrition 0.000 claims description 3
- 244000131522 Citrus pyriformis Species 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 239000006286 aqueous extract Substances 0.000 claims description 3
- 238000005119 centrifugation Methods 0.000 claims description 3
- 239000007888 film coating Substances 0.000 claims description 3
- 238000009501 film coating Methods 0.000 claims description 3
- 239000011122 softwood Substances 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 235000020985 whole grains Nutrition 0.000 claims description 3
- 235000013373 food additive Nutrition 0.000 claims description 2
- 239000002778 food additive Substances 0.000 claims description 2
- 239000002552 dosage form Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 abstract description 10
- 239000008280 blood Substances 0.000 abstract description 10
- 238000012545 processing Methods 0.000 abstract description 4
- 230000001502 supplementing effect Effects 0.000 abstract description 4
- 239000000463 material Substances 0.000 abstract description 3
- -1 tabletting Substances 0.000 abstract description 3
- 235000021393 food security Nutrition 0.000 abstract description 2
- 238000005728 strengthening Methods 0.000 abstract description 2
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 11
- 210000000952 spleen Anatomy 0.000 description 11
- 241000699666 Mus <mouse, genus> Species 0.000 description 9
- 210000004027 cell Anatomy 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 230000002708 enhancing effect Effects 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 210000001541 thymus gland Anatomy 0.000 description 6
- 229940079593 drug Drugs 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 230000006978 adaptation Effects 0.000 description 3
- 230000036737 immune function Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- XPCTZQVDEJYUGT-UHFFFAOYSA-N 3-hydroxy-2-methyl-4-pyrone Chemical compound CC=1OC=CC(=O)C=1O XPCTZQVDEJYUGT-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 210000001744 T-lymphocyte Anatomy 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 230000007969 cellular immunity Effects 0.000 description 2
- 230000001066 destructive effect Effects 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 229940089161 ginsenoside Drugs 0.000 description 2
- 229930182494 ginsenoside Natural products 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 230000002218 hypoglycaemic effect Effects 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 239000007928 intraperitoneal injection Substances 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000000265 leukocyte Anatomy 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000011574 phosphorus Substances 0.000 description 2
- 229910052698 phosphorus Inorganic materials 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000003612 virological effect Effects 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- 241001124076 Aphididae Species 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- 241001061264 Astragalus Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 235000019750 Crude protein Nutrition 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 206010061598 Immunodeficiency Diseases 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- HYMLWHLQFGRFIY-UHFFFAOYSA-N Maltol Natural products CC1OC=CC(=O)C1=O HYMLWHLQFGRFIY-UHFFFAOYSA-N 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 201000002451 Overnutrition Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000002929 anti-fatigue Effects 0.000 description 1
- 239000003005 anticarcinogenic agent Substances 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 235000006533 astragalus Nutrition 0.000 description 1
- 229960003237 betaine Drugs 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 231100000357 carcinogen Toxicity 0.000 description 1
- 239000003183 carcinogenic agent Substances 0.000 description 1
- 239000000496 cardiotonic agent Substances 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 230000010307 cell transformation Effects 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 235000019784 crude fat Nutrition 0.000 description 1
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 description 1
- 238000005034 decoration Methods 0.000 description 1
- 230000008260 defense mechanism Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000033065 inborn errors of immunity Diseases 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229940079322 interferon Drugs 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 229940043353 maltol Drugs 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 210000004493 neutrocyte Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 235000020823 overnutrition Nutrition 0.000 description 1
- 230000000242 pagocytic effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 208000028529 primary immunodeficiency disease Diseases 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000012797 qualification Methods 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 210000004988 splenocyte Anatomy 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 210000004233 talus Anatomy 0.000 description 1
- CEIZFXOZIQNICU-UHFFFAOYSA-N tenuazonic acid Chemical compound CCC(C)C1NC(=O)C(C(C)=O)=C1O CEIZFXOZIQNICU-UHFFFAOYSA-N 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 230000002992 thymic effect Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Immunity health food is improved the invention discloses one kind, its raw material includes taking by 10 200 parts of red ginseng extract of weight part, 10 100 parts of prepared rhizome of rehmannia, 10 100 parts of ganoderma lucidum, 10 100 parts of the Radix Astragali, 10 100 parts of matrimony vine, 20 100 parts of 1 80 parts of supplementary product starch and microcrystalline cellulose are added again, are made by dispensing, system material, tabletting, coating.The present invention is equipped with the prepared rhizome of rehmannia of nourishing yin and supplementing blood from the red ginseng strengthened the body resistance to consolidate the constitution, ganoderma lucidum, matrimony vine, then helps and formed using the Radix Astragali of invigorating qi for consolidating superficies as Raw material processing, by strengthening the body resistance to consolidate the constitution, nourishing yin and supplementing blood and reach the purpose for improving immunity, food security of the present invention is effective.The invention also discloses a kind of preparation method for improving immunity health food.
Description
Technical field
The present invention relates to health food manufacture field, a kind of raising immunity health food and preparation method are specifically referred to.
Technical background
Immunity is the defense mechanism of human body itself, is that human bioequivalence and any foreign matter for eliminating external intrusion are (viral, thin
Bacterium etc.);Handle aging, damage, death, the own cells of denaturation and identification and processing vivo mutations cell and virus infection is thin
The ability of born of the same parents.Modern civilization brings material enjoyment to the mankind, fundamentally changes the mankind original life style and habit, together
When also bring substantial amounts of negative effect to the mankind.Overnutrition causes various metabolic disorders, and vivotoxin excretion is obstructed, induced
Cardiovascular and cerebrovascular disease;The environment of indoor four seasons temperature control makes acarid, aphid, spore class and various bacteriums, viral amount reproduction, swims
In atmosphere, entered by respiratory tract in human body;Furniture, interior decoration, the art work of modernization are harmful entrainment of formaldehyde etc.
Carcinogen corrodes the health of the mankind.The effective immunity health food that improves increasingly is valued by people and welcome.
The content of the invention
It is an object of the invention to provide a kind of health food for having and improving immunity effect.
It is a further object to provide a kind of preparation method for the health food for having and improving immunity effect.
The technical scheme is that：
One kind improves immunity health food, including following raw materials according is made by weight ratio：
Red ginseng extract 10-200
Prepared rhizome of rehmannia 10-100
Ganoderma lucidum 10-100
Radix Astragali 10-100
Matrimony vine 10-100.
Further, a kind of described raising immunity health food, the raw material also includes starch 1-80 and food
Additive microcrystalline cellulose 20-100.
Further, the raw material proportioning is：
Red ginseng extract 80-100
Prepared rhizome of rehmannia 20-60
Ganoderma lucidum 20-60
Radix Astragali 20-60
Matrimony vine 20-60.
Further, the raw material proportioning is：
Red ginseng extract 80
Prepared rhizome of rehmannia 40
Ganoderma lucidum 40
The Radix Astragali 40
Matrimony vine 40.
Further, the red ginseng extract is prepared as follows：
A, according to parts by weight requirement weigh ginseng；
B, ginseng is cleaned after punch, according to ginseng shape and the difference of size, hole depth and be spaced about 0.5-1.2cm, then use lemon
Acid solution soaks 3h, under the conditions of 45-60 DEG C, dries 1h, is steamed, steamed after end afterwards, entered under the conditions of 45-60 DEG C
Row drying, is advisable to moisture content up to 13%-16%, gained red ginseng；
C, by red ginseng coarse crushing, plus 4-5 times is measured 70% ethanol, 85 DEG C, extracts 2 times, 8h/ time, then plus 4-5 times measure water, 85 DEG C, carry
Take 2 times, 8h/ times, merge Aqueous extracts and alcohol extract, filter, centrifugation is concentrated under reduced pressure, obtains thick paste, as red ginseng extract.
Further, the content of the raw material red ginseng extract in the food must not be less than 20%.
Further, the food is tablet form.
A kind of a kind of preparation method for improving immunity health food as described above, comprises the following steps：
1. dispensing：Take red ginseng extract 10-200 parts by weight, prepared rhizome of rehmannia 10-100 parts by weight, ganoderma lucidum 10-100 parts by weight, the Radix Astragali
10-100 parts by weight, matrimony vine 10-100 parts by weight, then 20-100 parts of starch 1-80 parts by weight and microcrystalline cellulose are added, mix
Make its uniform within 10-30 minutes；
2. pelletize：With 70-90% ethanol softwoods, the granulation of 16 mesh sieves, 55-60 DEG C of drying, 14 mesh sieve whole grains；
3. tabletting：Piece weight 0.6g/ pieces, control 18-25 DEG C of environment temperature, relative humidity 45%-60%；
4. it is coated：Bag uniform compact film-coating, controls 18-25 DEG C of environment temperature, relative humidity 45%-60%.
Red ginseng can strengthen respond of the body to various destructive stimuluses in the present invention, strengthen organism adaptation.It is used as machine
The conditioning agent of body function, ginsenoside is to physical (cold, overheat, aggravating activities, radioactive ray), (allosome of biology
Serum, bacterium, transplantation tumor), (poisonous substance, arcotic, hormone, anticarcinogen etc.) stress reaction caused by a variety of stimulations chemically
There is protective effect, the functional recovery of disorder can be made normal, someone is called adaptation immunogenic substance, and (one kind enhancing human body is non-specific
The material of property resistivity).
The Radix Astragali has invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, effect of expelling pus and promoting granulation.Modern pharmacological research, can strengthen non-spy
Specific immunological function and enhancing specific immune function, can dramatically increase the total white blood cells in blood, promote neutrophil leucocyte
And the phagocytic function and sterilizing ability of macrophage.Cellular immunity can be significantly increased, promotes lymph caused by PHA, COnA, PWM
Cell transformation, the composition such as astragalus polyose has significant immunological enhancement.
Prepared rhizome of rehmannia is sweet, tepor.Return liver and kidney channel, enter blood system, the soft and moist drop of matter.《Compendium of Materia Medica》Carry：Glutinous rehmannia gives birth to then Great Cold,
And cool blood, blood-head person need to use it, ripe then tepor, and kidney tonifying, and the blood person of declining need to use it.The many deficiency of Yin of man, preferably with prepared rhizome of rehmannia, Nv Ziduo
Blood-head, preferably uses radix rehmanniae recen." especially cultivated land, medicinal " fills out marrow, long muscle.Promoting vital essence and blood genernation, tonifying five zang organs is sharp knowledge, black beard and hair, logical
Blood vessels ".There are cardiac stimulant, diuresis, hypoglycemic and rise peripheral leukocytes, enhancing immunologic function etc. is acted on.
Ganoderma lucidum can strengthen the immunity of human body, because ganoderma lucidum contains the polysaccharide body of anticancer efficiency, in addition, also containing rich
Rich Ge element.Germanium can accelerate the metabolism of body, delay the aging of cell, can be sent out by inducing human body to produce interferon
Wave its antitumaous effect;
Matrimony vine contains glycine betaine, polysaccharide, crude fat, crude protein, carrotene, vitamin A, vitamin C, vitamin B1, vitamin
The nutritional ingredient such as B2 and calcium, phosphorus, iron, zinc, manganese, linoleic acid.There is enhancing nospecific immunity effect, suppress tumour, hypoglycemic, drop
Blood fat, it is antifatigue to wait function.
In above-mentioned raw materials, red ginseng extract be after high-temperature process, ginseng its ginsenoside of comparing, amino acid etc.
Content is reduced, but the double Glycosides Contents of arginine increase, and newly generates the compositions such as maltol, thus strengthen immunity effect more
By force.Prepared rhizome of rehmannia, ganoderma lucidum, the Radix Astragali, matrimony vine provide for enterprise's production with production qualification.The present invention is red from what is strengthened the body resistance to consolidate the constitution
Ginseng, ganoderma lucidum, matrimony vine, are equipped with the prepared rhizome of rehmannia of nourishing yin and supplementing blood, then help and formed using the Radix Astragali of invigorating qi for consolidating superficies as Raw material processing, pass through righting
Consolidate, nourishing yin and supplementing blood, immune response of the enhancing body to various destructive stimuluses strengthen organism adaptation, and enhancing specific immune is anti-
Should and cellular immunity, and Relationship with other Nutrient Elements is supplemented, so as to reach the purpose for improving immunity.Food security of the present invention has
Effect.
By red ginseng Oral Liquid On Mice immune organ spleen, thymic weight and determination of immunoglobulin, it is expanded on further
It improves the efficacy effect of immunity.
Test example 1：Influence of the health food of the present invention to mouse immune organ thymus gland, spleen weight
Method：Take inbred mouse (14-18g) 40, single sex is randomly divided into 4 groups, blank control group and treatment group.Medicine
After thing group grinds the tablet, be dissolved into physiological saline, basic, normal, high 3 dosage groups, dosage is followed successively by 100,250,
500mg/kg；Blank control group gives isometric physiological saline.It is 0.2ml/10g to give volume, 1 times/day of gastric infusion,
Successive administration 7 days, in next day after last dose, cervical dislocation puts to death mouse, weighs, take spleen, thymus gland, liver to claim wet
Weight, thymus gland or spleen index are used for the weight (mg) of thymus gland or spleen and body weight (g).
Result of the test：Improve influence of the immunity health food to mouse spleen index and thymus index
Conclusion (of pressure testing)：The high, medium and low dosage group of composition can improve the spleen index and thymus index of mouse.By spleen index data
It can be seen that, low dose group is compared with blank control group with significant difference (P ＜ 0.05), middle and high dosage group and blank control group
Compare with pole significant difference (P ＜ 0.01).
Test example 2：Influence of the health food of the present invention to the mouse immuning ball protein of immunocompromised
Method：Inbred mouse (14~18g) 30 is taken, single sex is randomly divided into 3 groups, blank control group, model group and medicine
Thing group.Blank control group：Normal raise does not make any processing in experiment process；Model group：Intraperitoneal injection 100mg/kg ring phosphorus
Acid amides causes hypoimmunity model, 1 time/d, for three days on end；Medicine group：Intraperitoneal injection 100mg/kg endoxan causes to exempt from
The low model of epidemic disease power, 1 time/d, for three days on end, and gives the tablet 1 time of embodiment 1 for first day, dosage is 250mg/kg in modeling
Gastric infusion, gives volume for 0.2ml/10g, above-mentioned be administered once is repeated after one week.Last dose cervical dislocation after 4 days
Mouse is put to death, it is sterile to take spleen.It is placed in the plate for filling appropriate sterile Hank ' s liquid, gently spleen is ground with tweezers, list is made
Individual cell suspension, through 200 mesh sieve net filtrations, cell is suspended in 1mL complete culture solution, adjusts cell concentration 1 × 109/
The 100 μ L splenocyte suspensions fully mixed, the bottom of sample feeding pipe, plus 20 μ L monoclonals are carefully added to micropipettor by L
Antibody, low-speed oscillation mixes 3S, and room temperature lucifuge is incubated 30min, in after countlerPREP broken red blood cells, with flow cytometer
Detect T cell subgroup content.Mainly include：Helper lymphocyte T (CD4+), cytotoxic T lymphocyte (CD8+), CD4
+/CD8+。
Result of the test：The influence of T cell subgroup
Model group is compared with normal blank control group：△ P ＜ 0.01；Medicine group is compared with model group：* P ＜ 0.01.
Conclusion (of pressure testing)：Compared with blank control group, model group mouse spleen CD4+ cell subsets percentage declines, and CD8+ is thin
Born of the same parents' subgroup percentage rises, and with pole significant difference, P ＜ 0.01, CD4+/CD8+ ratios are substantially reduced, poor with pole conspicuousness
It is different, P ＜ 0.01.And medicine group can substantially offset the effect that endoxan destroys immunity, with significant difference, P ＜ 0.01.
Embodiment
With reference to embodiment, the present invention is described in more detail.But skilled in the art realises that, following embodiments
It is not limiting the scope of the invention, any improvement and change made on the basis of the present invention, all guarantor in the present invention
Within the scope of shield.
Embodiment 1
Step one：Dispensing
By weight 80 parts of red ginseng extract, 40 parts of prepared rhizome of rehmannia, 60 parts of ganoderma lucidum, 40 parts of the Radix Astragali, 60 parts of matrimony vine, 20 parts of starch and food
The 40 parts of mixing of product additive microcrystalline cellulose make uniform for 20 minutes.Wherein, the red ginseng extract is prepared as follows：
A, according to parts by weight requirement weigh ginseng；
B, ginseng is cleaned after punch, according to ginseng shape and the difference of size, hole depth and be spaced about 0.5-1.2cm, then use lemon
Acid solution soaks 3h, under the conditions of 45-60 DEG C, dries 1h, is steamed, steamed after end afterwards, entered under the conditions of 45-60 DEG C
Row drying, is advisable to moisture content up to 13%-16%, gained red ginseng；
C, by red ginseng coarse crushing, plus 4-5 times is measured 70% ethanol, 85 DEG C, extracts 2 times, 8h/ time, then plus 4-5 times measure water, 85 DEG C, carry
Take 2 times, 8h/ times, merge Aqueous extracts and alcohol extract, filter, centrifugation is concentrated under reduced pressure, obtains thick paste, as red ginseng extract.
Step 2：Granulation
With 85% ethanol softwood, the granulation of 16 mesh sieves, 55-60 DEG C of drying, 14 mesh sieve whole grains.
Step 3：Tabletting
Tabletting, piece weight 0.6g/ pieces, controls 18-25 DEG C of environment temperature, relative humidity 45%-60%.
Step 4：It is coated
Bag uniform compact film-coating, controls 18-25 DEG C of environment temperature, relative humidity 45%-60%.
Embodiment 2
Step one：Dispensing
60 parts of red ginseng extract, 40 parts of prepared rhizome of rehmannia, 40 parts of ganoderma lucidum, 40 parts of the Radix Astragali, 40 parts of matrimony vine is taken to mix by weight 20 minutes
Make uniform.Red ginseng extract prepares be the same as Example 1.
Step 2 granulation, step 3 tabletting, step 4 are coated be the same as Example 1.
Embodiment 3
Step one：Dispensing
60 parts of red ginseng extract, 60 parts of prepared rhizome of rehmannia, 60 parts of ganoderma lucidum, 40 parts of the Radix Astragali, 40 parts of matrimony vine is taken to mix by weight 20 minutes
Make uniform.Red ginseng extract prepares be the same as Example 1.
Step 2 granulation, step 3 tabletting, step 4 are coated be the same as Example 1.
Embodiment 4
Step one：Dispensing
80 parts of red ginseng extract, 40 parts of prepared rhizome of rehmannia, 40 parts of ganoderma lucidum, 40 parts of the Radix Astragali, 40 parts of matrimony vine, starch 10 and food are taken by weight
Product additive microcrystalline cellulose 30, mixing makes uniform for 20 minutes.Red ginseng extract prepares be the same as Example 1.
Step 2 granulation, step 3 tabletting, step 4 are coated be the same as Example 1.
Claims (8)
1. one kind improves immunity health food, including following raw materials according is made by weight ratio：
Red ginseng extract 10-200
Prepared rhizome of rehmannia 10-100
Ganoderma lucidum 10-100
Radix Astragali 10-100
Matrimony vine 10-100.
2. a kind of raising immunity health food according to claim 1, it is characterised in that the raw material also includes shallow lake
Powder 1-80 and food additives microcrystalline cellulose 20-100.
3. raising immunity health food according to claim 1, it is characterised in that the raw material proportioning is：
Red ginseng extract 80-100
Prepared rhizome of rehmannia 20-60
Ganoderma lucidum 20-60
Radix Astragali 20-60
Matrimony vine 20-60.
4. a kind of immunity health food is improved according to claim 1, it is characterised in that the raw material proportioning is：
Red ginseng extract 80
Prepared rhizome of rehmannia 40
Ganoderma lucidum 40
The Radix Astragali 40
Matrimony vine 40.
5. according to a kind of any described raising immunity health foods of claim 1-4, it is characterised in that the red ginseng is extracted
Thing is prepared as follows：
A, according to parts by weight requirement weigh ginseng；
B, ginseng is cleaned after punch, according to ginseng shape and the difference of size, hole depth and be spaced about 0.5-1.2cm, then use lemon
Acid solution soaks 3h, under the conditions of 45-60 DEG C, dries 1h, is steamed, steamed after end afterwards, entered under the conditions of 45-60 DEG C
Row drying, is advisable to moisture content up to 13%-16%, gained red ginseng；
C, by red ginseng coarse crushing, plus 4-5 times is measured 70% ethanol, 85 DEG C, extracts 2 times, 8h/ time, then plus 4-5 times measure water, 85 DEG C, carry
Take 2 times, 8h/ times, merge Aqueous extracts and alcohol extract, filter, centrifugation is concentrated under reduced pressure, obtains thick paste, as red ginseng extract.
6. according to a kind of any described raising immunity health foods of claim 1-4, it is characterised in that in the food
The content of raw material red ginseng extract must not be less than 20%.
7. according to a kind of any described raising immunity health foods of claim 1-4, it is characterised in that the food is piece
Dosage form formula.
8. a kind of a kind of preparation method for improving immunity health food as claimed in claim 2, comprises the following steps：
1. dispensing：Take red ginseng extract 10-200 parts by weight, prepared rhizome of rehmannia 10-100 parts by weight, ganoderma lucidum 10-100 parts by weight, the Radix Astragali
10-100 parts by weight, matrimony vine 10-100 parts by weight, then 20-100 parts of starch 1-80 parts by weight and microcrystalline cellulose are added, mix
Make its uniform within 10-30 minutes；
2. pelletize：With 70-90% ethanol softwoods, the granulation of 16 mesh sieves, 55-60 DEG C of drying, 14 mesh sieve whole grains；
3. tabletting：Piece weight 0.6g/ pieces, control 18-25 DEG C of environment temperature, relative humidity 45%-60%；
4. it is coated：Bag uniform compact film-coating, controls 18-25 DEG C of environment temperature, relative humidity 45%-60%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710563304.2A CN107136510A (en) | 2017-07-12 | 2017-07-12 | One kind improves immunity health food and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710563304.2A CN107136510A (en) | 2017-07-12 | 2017-07-12 | One kind improves immunity health food and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107136510A true CN107136510A (en) | 2017-09-08 |
Family
ID=59776557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710563304.2A Pending CN107136510A (en) | 2017-07-12 | 2017-07-12 | One kind improves immunity health food and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107136510A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112998171A (en) * | 2021-04-13 | 2021-06-22 | 华南农业大学 | Compound polypeptide health-preserving drink and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102423410A (en) * | 2011-11-17 | 2012-04-25 | 金道山 | Health-care Chinese medicinal composition and preparation method thereof |
| CN103110889A (en) * | 2013-02-01 | 2013-05-22 | 北京东方红航天生物技术股份有限公司 | Traditional Chinese medicine for increasing immunity and preparation method thereof |
| CN103405577A (en) * | 2013-08-26 | 2013-11-27 | 通化卫京药业股份有限公司 | Pharmaceutical composition for enhancing immunity and relieving fatigue |
| CN103520318A (en) * | 2013-10-24 | 2014-01-22 | 重庆主流生物工程有限公司 | Traditional Chinese medicine composition of enhancing immune function and preparation method of composition |
| CN104605344A (en) * | 2015-01-05 | 2015-05-13 | 江西汇仁药业有限公司 | Health food for enhancing immunity and preparation method of health food |
-
2017
- 2017-07-12 CN CN201710563304.2A patent/CN107136510A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102423410A (en) * | 2011-11-17 | 2012-04-25 | 金道山 | Health-care Chinese medicinal composition and preparation method thereof |
| CN103110889A (en) * | 2013-02-01 | 2013-05-22 | 北京东方红航天生物技术股份有限公司 | Traditional Chinese medicine for increasing immunity and preparation method thereof |
| CN103405577A (en) * | 2013-08-26 | 2013-11-27 | 通化卫京药业股份有限公司 | Pharmaceutical composition for enhancing immunity and relieving fatigue |
| CN103520318A (en) * | 2013-10-24 | 2014-01-22 | 重庆主流生物工程有限公司 | Traditional Chinese medicine composition of enhancing immune function and preparation method of composition |
| CN104605344A (en) * | 2015-01-05 | 2015-05-13 | 江西汇仁药业有限公司 | Health food for enhancing immunity and preparation method of health food |
Non-Patent Citations (1)
| Title |
|---|
| JUNG-HYUN YI等: "Change of Ginsenoside composition in Red Ginseng Processed with Citric Acid", 《FOOD SCI. BIOTECHNOL.》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112998171A (en) * | 2021-04-13 | 2021-06-22 | 华南农业大学 | Compound polypeptide health-preserving drink and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102406163B (en) | Application of traditional Chinese medicine composition in preparation of health food or medicament for preventing and relieving physical fatigue | |
| US10820615B2 (en) | Powder formulation having a function of enhancing immunity and method for preparing the same | |
| CN103550244B (en) | A kind of Chinese herbal medicine compound polysaccharide and application with collaboration enhancing body fluid and immunization of cell | |
| CN105661515A (en) | Enzyme lozenges for three-hypers and preparation method thereof | |
| CN103735662A (en) | Pharmaceutical composition of ginseng and donkey-hide gelatin as well as preparation method and use thereof | |
| CN107647395A (en) | It is a kind of that there is health food for improving immunity function and preparation method thereof | |
| CN110651941A (en) | Cordyceps militaris and Chinese yam solid beverage and production device thereof | |
| CN101664180A (en) | Health-care nutritional complexing agent with effect of and preparation method thereof | |
| CN105876439A (en) | Immunity-enhancing and fatigue-resisting traditional Chinese medicine health-care product and preparation method thereof | |
| JPH07284375A (en) | Immune-enhanced food compound mainly of isaria-type 'tochu-kaso' | |
| CN107136510A (en) | One kind improves immunity health food and preparation method thereof | |
| CN103463177A (en) | Traditional Chinese medicine health care product for improving and enhancing organism immunity | |
| WO1995018626A1 (en) | A tonic drug made from basidiomycetes, algae, chinese herbal medicine and the method thereof | |
| CN105687480A (en) | Immunoregulatory traditional Chinese medicine composition and preparation | |
| CN107136499B (en) | Compound preparation for enhancing immunity of tumor patients after operation | |
| CN105639270A (en) | Tablet for enhancing immunity and production method thereof | |
| CN102078600B (en) | Anti-cancer compound ganoderma composition, application thereof and pharmaceutical composition containing same | |
| CN107893035A (en) | A kind of culture medium of Hericium erinaceus, sealwort bioconversion mycelium, the mycelial extract of sealwort bioconversion and application thereof | |
| CN106214844A (en) | A kind of compositions with fat-reducing and immunoregulation effect and preparation method thereof | |
| CN107536016B (en) | A nutritional food for protecting heart and promoting liver health | |
| CN103230003B (en) | Health food with immunity boosting function and preparation method thereof | |
| CN108114120A (en) | It is a kind of to be used to adjust cordyceps wine of blood fat and preparation method thereof | |
| CN104001143A (en) | Phellinus igniarius tablets and preparing method thereof | |
| CN110663948A (en) | Health product with immunity enhancing effect and preparation method thereof | |
| CN111329061A (en) | A medicated diet product for enhancing immunity, and its preparation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170908 |
|
| RJ01 | Rejection of invention patent application after publication |