CN107073350B - 用于产生液滴的液体给送装置 - Google Patents

用于产生液滴的液体给送装置 Download PDF

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Publication number
CN107073350B
CN107073350B CN201580039297.5A CN201580039297A CN107073350B CN 107073350 B CN107073350 B CN 107073350B CN 201580039297 A CN201580039297 A CN 201580039297A CN 107073350 B CN107073350 B CN 107073350B
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CN
China
Prior art keywords
liquid
section
droplets
deflection
nozzle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201580039297.5A
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English (en)
Chinese (zh)
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CN107073350A (zh
Inventor
托马斯·格布哈特
罗兰·凯泽
伯恩哈德·卢伊
马蒂亚斯·普利茨科
曼弗雷德·施特鲁施卡
克里斯蒂安·泽里洛
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Senauer Faye Basudeb AG
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Senauer Faye Basudeb AG
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Publication of CN107073350A publication Critical patent/CN107073350A/zh
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Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F26B5/065—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/16—Evaporating by spraying
    • B01D1/18—Evaporating by spraying to obtain dry solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/18—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Coating Apparatus (AREA)
  • Nozzles (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Glanulating (AREA)
  • Drying Of Solid Materials (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
  • Medicinal Preparation (AREA)
CN201580039297.5A 2014-07-21 2015-07-20 用于产生液滴的液体给送装置 Active CN107073350B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14002529 2014-07-21
EP14002529.7 2014-07-21
PCT/EP2015/066583 WO2016012414A1 (en) 2014-07-21 2015-07-20 Liquid feeding device for the generation of droplets

Publications (2)

Publication Number Publication Date
CN107073350A CN107073350A (zh) 2017-08-18
CN107073350B true CN107073350B (zh) 2019-11-15

Family

ID=51229796

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580039297.5A Active CN107073350B (zh) 2014-07-21 2015-07-20 用于产生液滴的液体给送装置

Country Status (10)

Country Link
US (2) US10533800B2 (enExample)
EP (1) EP3171954B1 (enExample)
JP (1) JP6166006B1 (enExample)
KR (1) KR101774203B1 (enExample)
CN (1) CN107073350B (enExample)
AU (1) AU2015293983B2 (enExample)
BR (1) BR112016031039B1 (enExample)
CA (2) CA2955562C (enExample)
DK (1) DK3171954T3 (enExample)
WO (1) WO2016012414A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2955562C (en) * 2014-07-21 2018-05-22 Thomas Gebhard Liquid feeding device for the generation of droplets
JP6971043B2 (ja) 2016-03-04 2021-11-24 株式会社リコー 微粒子の製造方法
TWI860477B (zh) * 2020-05-18 2024-11-01 日商Ｍｉｉ股份有限公司 真空凍結乾燥裝置及真空凍結乾燥方法
CN111992433B (zh) * 2020-08-17 2022-03-04 重庆煜兆耀电子科技有限公司 一种可根据胶水粘稠度调整气压的led灯点胶装置
CN111821913A (zh) * 2020-08-19 2020-10-27 中国科学技术大学 一种高通量制备均匀双乳液滴的装置及方法
CN112460925B (zh) * 2020-10-28 2022-04-12 靖州康源苓业科技股份有限公司 一种冻干茯苓的生产加工设备及方法
JP7085088B1 (ja) * 2021-08-03 2022-06-16 株式会社エムアイアイ 凍結乾燥物
WO2023057444A1 (en) 2021-10-05 2023-04-13 Sanofi METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPs) AND LNPs OBTAINED WITH THE SAME
CN114459211B (zh) * 2022-01-22 2023-04-07 上海田枫实业有限公司 一种冻干机
CN116135276B (zh) * 2023-04-18 2023-07-04 常州一步干燥设备有限公司 一种喷雾干燥机及其气扫装置

Citations (7)

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US4376944A (en) * 1981-04-13 1983-03-15 Ncr Corporation Ink jet print head with tilting nozzle
US5828394A (en) * 1995-09-20 1998-10-27 The Board Of Trustees Of The Leland Stanford Junior University Fluid drop ejector and method
US6095889A (en) * 1999-01-25 2000-08-01 Demarinis; Paul M. Interactive entertainment device
US6863385B2 (en) * 2000-12-28 2005-03-08 Eastman Kodak Company Continuous ink-jet printing method and apparatus
CN1820953A (zh) * 2005-02-16 2006-08-23 精工爱普生株式会社 功能液供给装置的控制方法、功能液供给装置
EP2101131A1 (en) * 2007-12-31 2009-09-16 Terruzzi Fercalx S.p.A. Lyophilization method and system therefor
CN101959527A (zh) * 2008-03-05 2011-01-26 赛诺菲巴斯德有限公司 一种使含佐剂的疫苗组合物稳定的方法

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Publication number Priority date Publication date Assignee Title
US3601901A (en) 1969-09-12 1971-08-31 Earl L Rader Freeze drying apparatus with removable conveyor and heater structures
JPH08121529A (ja) * 1994-10-25 1996-05-14 Toyoda Gosei Co Ltd 防振装置
CA2327716A1 (en) * 1998-03-07 1999-09-10 Inotech Ag Method and device for capsulating microbial, plant and animal cells or biological and chemical substances
JP3956224B2 (ja) * 2002-09-24 2007-08-08 コニカミノルタホールディングス株式会社 液体吐出装置
KR100966673B1 (ko) * 2002-09-24 2010-06-29 코니카 미놀타 홀딩스 가부시키가이샤 정전 흡인형 액체 토출 헤드의 제조 방법, 노즐 플레이트의제조 방법, 정전 흡인형 액체 토출 헤드의 구동 방법,정전 흡인형 액체 토출 장치 및 액체 토출 장치
FR2862306B1 (fr) 2003-11-17 2008-05-30 Aventis Pasteur Composition vaccinale
WO2005105253A1 (en) 2004-05-01 2005-11-10 Agresearch Limited Drying process and apparatus
FR2873222A1 (fr) * 2004-07-13 2006-01-20 Neopost Ind Sa Systeme d'affranchissement a niveau d'encre controle
DK1794524T3 (da) * 2004-07-23 2012-04-16 Bayer Technology Services Gmbh Fremgangsmåde til frysning, tørring, lagring, analysering og fyldning (SFD-SAF-fremgangsmåde) (fremgangsmåde til frysetørring af piller til parenterale biologiske lægemidler)
US20060139416A1 (en) * 2004-12-24 2006-06-29 Fuji Photo Film Co., Ltd. Fine droplet ejecting device and ink jet recording apparatus using the same
US20060165717A1 (en) 2005-01-25 2006-07-27 Sanofi Pasteur DCchol in newborns
DE102005018949A1 (de) * 2005-04-18 2006-10-19 Ami-Agrolinz Melamine International Gmbh Harnstoffpartikel, Verfahren zu dessen Herstellung und dessen Verwendung
AR054822A1 (es) 2005-07-07 2007-07-18 Sanofi Pasteur Emulsion inmuno adyuvante
JP4589225B2 (ja) 2005-12-22 2010-12-01 東洋エンジニアリング株式会社 顆粒製品の製造方法
JP5156199B2 (ja) * 2006-05-31 2013-03-06 高園産業株式会社 水薬供給装置
PL2043682T3 (pl) 2006-07-17 2014-09-30 Glaxosmithkline Biologicals Sa Szczepionka przeciw grypie
EP2058131A1 (en) 2007-11-09 2009-05-13 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Droplet selection mechanism
EP2578974A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Process line for the production of freeze-dried particles
US9321071B2 (en) * 2012-09-28 2016-04-26 Amastan Technologies Llc High frequency uniform droplet maker and method
CN103727175A (zh) * 2014-01-13 2014-04-16 天津大学 以电磁方式回收振动能量的橡胶扭振减振器
CA2955562C (en) 2014-07-21 2018-05-22 Thomas Gebhard Liquid feeding device for the generation of droplets

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376944A (en) * 1981-04-13 1983-03-15 Ncr Corporation Ink jet print head with tilting nozzle
US5828394A (en) * 1995-09-20 1998-10-27 The Board Of Trustees Of The Leland Stanford Junior University Fluid drop ejector and method
US6095889A (en) * 1999-01-25 2000-08-01 Demarinis; Paul M. Interactive entertainment device
US6863385B2 (en) * 2000-12-28 2005-03-08 Eastman Kodak Company Continuous ink-jet printing method and apparatus
CN1820953A (zh) * 2005-02-16 2006-08-23 精工爱普生株式会社 功能液供给装置的控制方法、功能液供给装置
EP2101131A1 (en) * 2007-12-31 2009-09-16 Terruzzi Fercalx S.p.A. Lyophilization method and system therefor
CN101959527A (zh) * 2008-03-05 2011-01-26 赛诺菲巴斯德有限公司 一种使含佐剂的疫苗组合物稳定的方法

Also Published As

Publication number Publication date
AU2015293983B2 (en) 2017-02-09
US20200141647A1 (en) 2020-05-07
US11499777B2 (en) 2022-11-15
EP3171954A1 (en) 2017-05-31
JP6166006B1 (ja) 2017-07-19
CA2955562A1 (en) 2016-01-28
JP2017533397A (ja) 2017-11-09
KR20170023189A (ko) 2017-03-02
WO2016012414A1 (en) 2016-01-28
CN107073350A (zh) 2017-08-18
CA3000093C (en) 2019-07-09
BR112016031039A2 (enExample) 2017-08-22
US20170219283A1 (en) 2017-08-03
CA3000093A1 (en) 2016-01-28
DK3171954T3 (en) 2018-08-06
EP3171954B1 (en) 2018-06-27
US10533800B2 (en) 2020-01-14
BR112016031039B1 (pt) 2022-02-15
CA2955562C (en) 2018-05-22
KR101774203B1 (ko) 2017-09-01

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