CN107073199B - 可变剂量的药物自动注射装置 - Google Patents

可变剂量的药物自动注射装置 Download PDF

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Publication number
CN107073199B
CN107073199B CN201580045106.6A CN201580045106A CN107073199B CN 107073199 B CN107073199 B CN 107073199B CN 201580045106 A CN201580045106 A CN 201580045106A CN 107073199 B CN107073199 B CN 107073199B
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China
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push rod
injection
container
input device
dose
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CN201580045106.6A
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Chinese (zh)
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CN107073199A (zh
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魏民
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159Dose expelling manners
    • A61M5/31593Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31536Blocking means to immobilize a selected dose, e.g. to administer equal doses
    • A61M5/31538Permanent blocking, e.g. by medical personnel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/3155Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31563Mechanically operated dose setting member interacting with a displaceable stop member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566Means improving security or handling thereof
    • A61M5/31571Means preventing accidental administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2026Semi-automatic, e.g. user activated piston is assisted by additional source of energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206With automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps
    • A61M5/3204Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201580045106.6A 2014-09-05 2015-08-28 可变剂量的药物自动注射装置 Active CN107073199B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462046191P 2014-09-05 2014-09-05
US62/046191 2014-09-05
US201562155509P 2015-05-01 2015-05-01
US62/155509 2015-05-01
PCT/US2015/047477 WO2016036600A1 (en) 2014-09-05 2015-08-28 Automatic injection device with variable dosing

Publications (2)

Publication Number Publication Date
CN107073199A CN107073199A (zh) 2017-08-18
CN107073199B true CN107073199B (zh) 2020-08-18

Family

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CN201580045106.6A Active CN107073199B (zh) 2014-09-05 2015-08-28 可变剂量的药物自动注射装置

Country Status (5)

Country Link
US (2) US10603444B2 (enExample)
EP (1) EP3188772B1 (enExample)
JP (1) JP6449990B2 (enExample)
CN (1) CN107073199B (enExample)
WO (1) WO2016036600A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111447961B (zh) * 2017-12-04 2024-12-31 诺和诺德股份有限公司 用于基于扭转弹簧的装置的弹簧应变机构
AU2019273832B2 (en) 2018-05-24 2022-03-31 Novartis Ag Automatic drug delivery device
WO2020008381A1 (en) * 2018-07-06 2020-01-09 Zekhnareh Mohsen Secure syringe click lock preventing needle release and drug leakage
TWI670097B (zh) * 2018-10-24 2019-09-01 群康生技股份有限公司 具有注射劑量調整功能的注射器
US11744951B2 (en) 2018-10-24 2023-09-05 Cc Biotechnology Corporation Syringe with injection dose adjustment function
CN109772218B (zh) * 2018-12-30 2021-06-22 浙江省海洋水产研究所 定量试剂注射装置
CN110141728B (zh) * 2019-05-10 2020-12-22 江苏德尔福医疗器械有限公司 便于注射的注射笔套
CN111407977B (zh) * 2020-04-08 2022-10-21 北京航宇阳光机电技术研究所 一种自动注射装置
USD936218S1 (en) * 2020-06-04 2021-11-16 Ultradent Products, Inc. Unit dose container
CH717905A2 (de) * 2020-09-30 2022-03-31 Ypsomed Ag Autoinjektor mit Ausschüttstopp.

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5391151A (en) * 1991-01-15 1995-02-21 Survival Technology, Inc. Subcutaneous injector
US5480387A (en) * 1991-07-24 1996-01-02 Medico Development Investment Company Injection device
US5514097A (en) * 1994-02-14 1996-05-07 Genentech, Inc. Self administered injection pen apparatus and method
US20070265568A1 (en) * 2004-11-04 2007-11-15 Izrail Tsals Automatic Injector
CN102202710A (zh) * 2008-09-18 2011-09-28 贝克顿·迪金森公司 具有可旋转主体部的医用注射器

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2539302B1 (fr) * 1983-01-17 1986-03-14 Brunet Jean Louis Seringue a usage medical
JP2005000203A (ja) * 2003-06-09 2005-01-06 Nemoto Kyorindo:Kk 薬液注入システム
GB2410188B (en) * 2004-01-23 2006-01-25 Medical House Plc Injection device
ZA200703707B (en) * 2004-10-21 2009-02-25 Novo Nordisk As Dial-Down Mechanism for Wind-up Pen
GB2433032A (en) * 2005-12-08 2007-06-13 Owen Mumford Ltd Syringe with dose adjustment means
US9192727B2 (en) * 2006-05-18 2015-11-24 Novo Nordisk A/S Injection device with mode locking means
GB2467904B (en) * 2009-02-17 2013-06-12 Oval Medical Technologies Ltd Drug container and delivery mechanism
JP5461708B2 (ja) * 2009-12-15 2014-04-02 エス・ホー・エル・グループ・アクチボラゲット 薬剤送達装置
CA2848242C (en) * 2011-09-09 2019-12-24 Merck Patent Gmbh Reloadable auto-injector

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5391151A (en) * 1991-01-15 1995-02-21 Survival Technology, Inc. Subcutaneous injector
US5480387A (en) * 1991-07-24 1996-01-02 Medico Development Investment Company Injection device
US5514097A (en) * 1994-02-14 1996-05-07 Genentech, Inc. Self administered injection pen apparatus and method
US20070265568A1 (en) * 2004-11-04 2007-11-15 Izrail Tsals Automatic Injector
CN102202710A (zh) * 2008-09-18 2011-09-28 贝克顿·迪金森公司 具有可旋转主体部的医用注射器

Also Published As

Publication number Publication date
WO2016036600A1 (en) 2016-03-10
EP3188772A4 (en) 2018-08-01
CN107073199A (zh) 2017-08-18
EP3188772B1 (en) 2024-06-05
JP2017525466A (ja) 2017-09-07
US11065391B2 (en) 2021-07-20
US20200171247A1 (en) 2020-06-04
EP3188772A1 (en) 2017-07-12
US20170239424A1 (en) 2017-08-24
JP6449990B2 (ja) 2019-01-09
US10603444B2 (en) 2020-03-31

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