CN107072765A - 用于治疗后眼病症的方法和装置 - Google Patents

用于治疗后眼病症的方法和装置 Download PDF

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Publication number
CN107072765A
CN107072765A CN201580044250.8A CN201580044250A CN107072765A CN 107072765 A CN107072765 A CN 107072765A CN 201580044250 A CN201580044250 A CN 201580044250A CN 107072765 A CN107072765 A CN 107072765A
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CN
China
Prior art keywords
drug
eye
dose
antibody
uveitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580044250.8A
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English (en)
Chinese (zh)
Inventor
G·诺罗尼亚
C·J·布鲁克斯
R·V·安迪诺
S·帕特尔
D·怀特
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Clearside Biomedical Inc
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Clearside Biomedical Inc
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Filing date
Publication date
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Publication of CN107072765A publication Critical patent/CN107072765A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Mycology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201580044250.8A 2014-06-17 2015-06-17 用于治疗后眼病症的方法和装置 Pending CN107072765A (zh)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201462013209P 2014-06-17 2014-06-17
US62/013,209 2014-06-17
US201462018148P 2014-06-27 2014-06-27
US62/018,148 2014-06-27
US201462063792P 2014-10-14 2014-10-14
US62/063,792 2014-10-14
US201562155367P 2015-04-30 2015-04-30
US62/155,367 2015-04-30
US201562156802P 2015-05-04 2015-05-04
US62/156,802 2015-05-04
PCT/US2015/036299 WO2015195842A1 (en) 2014-06-17 2015-06-17 Methods and devices for treating posterior ocular disorders

Publications (1)

Publication Number Publication Date
CN107072765A true CN107072765A (zh) 2017-08-18

Family

ID=54936084

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580044250.8A Pending CN107072765A (zh) 2014-06-17 2015-06-17 用于治疗后眼病症的方法和装置

Country Status (12)

Country Link
US (1) US20180042765A1 (https=)
EP (1) EP3157463A4 (https=)
JP (2) JP6774340B2 (https=)
KR (1) KR102511477B1 (https=)
CN (1) CN107072765A (https=)
AU (1) AU2015277133A1 (https=)
BR (1) BR112016029864A2 (https=)
CA (1) CA2952822A1 (https=)
IL (1) IL249602A0 (https=)
MX (1) MX2016016836A (https=)
RU (1) RU2017101236A (https=)
WO (1) WO2015195842A1 (https=)

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CN110009626A (zh) * 2019-04-11 2019-07-12 北京百度网讯科技有限公司 用于生成图像的方法和装置
CN113101502A (zh) * 2021-03-01 2021-07-13 李特 一种耳鼻喉科用治疗装置
CN113198003A (zh) * 2021-06-22 2021-08-03 万永年 一种用于皮肤损伤后预防萎缩性疤痕外用液及其制备方法
CN113853185A (zh) * 2019-03-21 2021-12-28 迈克罗欧普提克斯股份有限公司 可植入眼部药物递送装置和方法
TWI890114B (zh) * 2022-08-16 2025-07-11 美商奧伊斯特普安生物製藥公司 將藥物無菌地轉移至藥物遞送裝置的藥物轉移系統及方法

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MX373894B (es) 2012-11-08 2020-07-09 Clearside Biomedical Inc Métodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos.
BR112015027762A2 (pt) 2013-05-03 2017-08-29 Clearside Biomedical Inc Aparelho e métodos para injeção ocular
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US9949874B2 (en) 2014-06-06 2018-04-24 Janssen Biotech, Inc. Therapeutic agent delivery device with convergent lumen
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US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
US10219936B2 (en) 2014-09-11 2019-03-05 Orbit Biomedical Limited Therapeutic agent delivery device with advanceable cannula and needle
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
TWI806150B (zh) * 2014-11-07 2023-06-21 瑞士商諾華公司 穩定的含有高濃度抗vegf抗體之蛋白質溶液調配物
KR20250057128A (ko) 2015-12-30 2025-04-28 코디악 사이언시스 인코포레이티드 항체 및 이의 접합체
CA3010862A1 (en) * 2016-01-08 2017-07-13 Clearside Biomedical, Inc. Methods and devices for treating posterior ocular disorderswith aflibercept and other biologics
CN109414577A (zh) * 2016-01-19 2019-03-01 皮博士研究所有限责任公司 用于制剂加工的装置及方法
US10390901B2 (en) 2016-02-10 2019-08-27 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
US10478553B2 (en) 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle
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US11000410B2 (en) 2016-06-17 2021-05-11 Gyroscope Therapeutics Limited Guide apparatus for tangential entry into suprachoroidal space
US10646374B2 (en) 2016-06-17 2020-05-12 Orbit Biomedical Limited Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent
US10806629B2 (en) 2016-06-17 2020-10-20 Gyroscope Therapeutics Limited Injection device for subretinal delivery of therapeutic agent
IL305537B2 (en) 2016-08-12 2025-02-01 Clearside Biomedical Inc Devices and methods for adjusting the insertion depth of a needle for administering a drug
US11273072B2 (en) 2017-01-13 2022-03-15 Gyroscope Therapeutics Limited Suprachoroidal injection device
AU2018230478B2 (en) 2017-03-09 2025-01-23 Diamedica Inc. Dosage forms of tissue kallikrein 1
US11076984B2 (en) 2017-03-13 2021-08-03 Gyroscope Therapeutics Limited Method of performing subretinal drainage and agent delivery
US12090294B2 (en) 2017-05-02 2024-09-17 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
WO2019133690A1 (en) * 2017-12-28 2019-07-04 Nichiban Co., Ltd. Transdermal drug delivery system and method for using same
US11724941B2 (en) 2018-02-15 2023-08-15 North Carolina State University Synthesis of micron and nanoscale carbon spheres and structures using hydrothemal carbonization
EP3758737A4 (en) 2018-03-02 2022-10-12 Kodiak Sciences Inc. IL-6 ANTIBODIES AND FUSION CONSTRUCTS AND CONJUGATES THEREOF
US20210046002A1 (en) * 2018-03-05 2021-02-18 Massachusetts Eye And Ear Infirmary Amelioration of autoimmune uveitis through blockade of csf1r
WO2019217678A1 (en) * 2018-05-09 2019-11-14 North Carolina State University Applicator for corneal therapeutics
CA3136814A1 (en) 2019-04-16 2020-10-22 Clearside Biomedical, Inc. Injectable triamcinolone formulations
EP3886946A1 (en) 2019-06-05 2021-10-06 Regeneron Pharmaceuticals, Inc. Devices and methods for precision dose delivery
CA3157509A1 (en) 2019-10-10 2021-04-15 Kodiak Sciences Inc. Methods of treating an eye disorder
CA3171479A1 (en) * 2020-02-19 2021-08-26 Clearside Biomedical, Inc. Compositions comprising axitinib and methods of treating ocular disorders
KR102888055B1 (ko) * 2020-07-17 2025-11-21 에스에이치엘 메디컬 아게 마이크로 투여 장치 및 마이크로 투여 장치의 조립 방법
US20240000443A1 (en) * 2020-11-30 2024-01-04 Visionaire Products, Inc. Needle and collection device for ocular biopsy and methods of use
US20240000782A1 (en) * 2020-12-02 2024-01-04 Telios Pharma, Inc. Methods and compositions for treating an ophthalmic condition
JP2024500871A (ja) * 2020-12-17 2024-01-10 モビアス セラピューティクス， エルエルシー 注射装置および使用方法
US20250177417A1 (en) * 2022-01-06 2025-06-05 Clearside Biomedical, Inc. Compositions and methods for treating macular edema associated with uveitis
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USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
AU2024287943A1 (en) * 2023-07-10 2026-01-22 Eden Ophthalmic Pte Ltd. Liposomal formulations of corticosteroids and uses thereof
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CN103857431A (zh) * 2011-10-07 2014-06-11 赛诺菲-安万特德国有限公司 用于眼内注射的装置

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Cited By (6)

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Publication number Priority date Publication date Assignee Title
CN113853185A (zh) * 2019-03-21 2021-12-28 迈克罗欧普提克斯股份有限公司 可植入眼部药物递送装置和方法
CN110009626A (zh) * 2019-04-11 2019-07-12 北京百度网讯科技有限公司 用于生成图像的方法和装置
CN113101502A (zh) * 2021-03-01 2021-07-13 李特 一种耳鼻喉科用治疗装置
CN113101502B (zh) * 2021-03-01 2023-01-17 李特 一种耳鼻喉科用治疗装置
CN113198003A (zh) * 2021-06-22 2021-08-03 万永年 一种用于皮肤损伤后预防萎缩性疤痕外用液及其制备方法
TWI890114B (zh) * 2022-08-16 2025-07-11 美商奧伊斯特普安生物製藥公司 將藥物無菌地轉移至藥物遞送裝置的藥物轉移系統及方法

Also Published As

Publication number Publication date
EP3157463A4 (en) 2018-02-21
WO2015195842A1 (en) 2015-12-23
KR20170039128A (ko) 2017-04-10
US20180042765A1 (en) 2018-02-15
MX2016016836A (es) 2017-07-27
AU2015277133A1 (en) 2017-02-02
KR102511477B1 (ko) 2023-03-16
BR112016029864A2 (pt) 2017-08-22
JP2017524677A (ja) 2017-08-31
JP6774340B2 (ja) 2020-10-21
IL249602A0 (en) 2017-02-28
CA2952822A1 (en) 2015-12-23
RU2017101236A3 (https=) 2019-05-16
RU2017101236A (ru) 2018-07-17
EP3157463A1 (en) 2017-04-26
JP2020063236A (ja) 2020-04-23

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