CN107051366B - A kind of continuous flow tubular reactor system and reaction control system - Google Patents
A kind of continuous flow tubular reactor system and reaction control system Download PDFInfo
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- CN107051366B CN107051366B CN201710433895.1A CN201710433895A CN107051366B CN 107051366 B CN107051366 B CN 107051366B CN 201710433895 A CN201710433895 A CN 201710433895A CN 107051366 B CN107051366 B CN 107051366B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/24—Stationary reactors without moving elements inside
- B01J19/2415—Tubular reactors
- B01J19/242—Tubular reactors in series
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0006—Controlling or regulating processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0006—Controlling or regulating processes
- B01J19/0013—Controlling the temperature of the process
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/24—Stationary reactors without moving elements inside
- B01J19/2415—Tubular reactors
- B01J19/243—Tubular reactors spirally, concentrically or zigzag wound
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00051—Controlling the temperature
- B01J2219/00054—Controlling or regulating the heat exchange system
- B01J2219/00056—Controlling or regulating the heat exchange system involving measured parameters
- B01J2219/00058—Temperature measurement
- B01J2219/0006—Temperature measurement of the heat exchange medium
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00164—Controlling or regulating processes controlling the flow
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00189—Controlling or regulating processes controlling the stirring velocity
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/24—Stationary reactors without moving elements inside
- B01J2219/2401—Reactors comprising multiple separate flow channels
- B01J2219/2402—Monolithic-type reactors
- B01J2219/2409—Heat exchange aspects
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/24—Stationary reactors without moving elements inside
- B01J2219/2401—Reactors comprising multiple separate flow channels
- B01J2219/2402—Monolithic-type reactors
- B01J2219/2418—Feeding means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/24—Stationary reactors without moving elements inside
- B01J2219/2401—Reactors comprising multiple separate flow channels
- B01J2219/2402—Monolithic-type reactors
- B01J2219/2422—Mixing means, e.g. fins or baffles attached to the monolith or placed in the channel
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
The present invention relates to chemical pharmaceutical technical fields, more particularly to a kind of continuous flow tubular reactor system and reaction control system, reaction system includes the feed arrangement, mixing arrangement, preheating device and the reaction unit that are sequentially communicated, reaction tube in reaction unit is sequentially communicated by communication apparatus, reaction control system includes the input unit for selecting default reaction pattern, and control signal is exported according to the reaction pattern of selection, control continuous flow tubular reactor system according to reaction condition normal operation control unit.The continuous flow tubular reactor system and reaction control system of the present invention, good mixing effect, reaction condition control are accurate, reaction efficiency and yield rate are improved, volume and space are smaller, reduce production cost, using spirally-wound reaction tube, good mixing effect, equipment life is long.
Description
Technical field
The present invention relates to chemical pharmaceutical technical fields, and in particular to a kind of continuous flow tubular reactor system and reaction controlling system
System.
Background technology
The common reactor apparatus of chemical pharmaceutical technical field includes tubular reactor and tank reactor etc., wherein autoclave
Reactor is often packed into agitating device in a kettle, for liquid phase reactor object mix, synthetic purity, reaction conversion ratio compared with
Low, energy consumption and pollution are more serious.Since field of chemical pharmacy is more demanding to the purity of product etc., the reaction often used
Device equipment is continuous flow tubular reactor.
Chemical reactant concentration in tubular reactor changes with reaction rate with pipe range, therefore tubular reactor needs completely
Foot chemically reacts required pipe range, and existing straight tube reactor or U-tube reactor will accomplish longer pipe range, then reactor
Volume is too big.In addition, existing tubular reactor, can not complete to chemically react required reaction condition well, as mass transfer,
Conduct heat it is required be sufficiently mixed, accurate temperature controlling, enough tube length of reaction tube and the corresponding data of on-line checking etc..
Invention content
The present invention proposes a kind of continuous flow tubular reactor system and reaction control system, to solve existing pipe reaction system
System takes up a large area, and mass transfer, heat transfer mixing are not uniform enough, can not accomplish the technical problems such as accurate temperature controlling and on-line monitoring.
The present invention continuous flow tubular reactor system, including be sequentially communicated feed arrangement, mixing arrangement, preheating device and
Reaction unit,
The feed arrangement includes multigroup sequentially connected head tank, feed pump and flow controller, each raw material
For containing a kind of reaction solution, the flow controller is used to control the feed pump from the head tank with a constant speed tank
Rate abstraction reaction solution；
Agitating paddle is installed, the agitating paddle is driven by servo motor, for will be from the raw material in the mixing arrangement
The reaction solution extracted in tank is mixed, and obtains mixed solution；
The preheating device includes preheating tube side and preheating shell side, described to preheat tube side for circulating from the mixing arrangement
The mixed solution of importing, the preheating shell side are used for the pre- thermal medium to circulate for preheating reactant；
The reaction unit includes reactor shell, and the lower part of the reactor shell is provided with shell side inlet, described anti-
The top of device housing is answered to be provided with shell-side outlet, is used to circulate to heat reactant inside the shell side of the reactor shell
Heat medium；The upper and lower ends of the reactor shell are respectively connected with tube sheet and communication apparatus, the inside of the reactor shell
It is provided with the reaction tube group for the reactant that circulates, the reaction tube group includes more reaction tubes, and up and down the two of every reaction tube
It holds across and is fixedly connected on the tube sheet, all reaction tubes are sequentially communicated by the communication apparatus.
Preferably, reactant entrance and reactant exit are provided on the communication apparatus of the reactor shell lower end,
The reactant entrance connects the preheating device, and the reactant exit connects products pot.
Preferably, it is provided with temperature instrument, pressure detecting instrument on the communication apparatus of the reactor shell upper end
Table and flow rate detection instrument, for measuring temperature, pressure and the flow speed data in the reaction tube.
Preferably, the communication apparatus uses baffling bobbin carriage, it is provided on the baffling bobbin carriage and multiple is reacted with described
The adjacent corresponding baffling slot of two reaction tubes in pipe communication direction, all reaction tubes by the baffling slot on baffling bobbin carriage successively
Connection.
It is set preferably, the more reaction tubes are wound with certain helix angle.
It is described including input unit and control unit the invention also discloses a kind of continuous flow pipe reaction control system
Input unit is for selecting preset reaction pattern, and the reaction pattern that described control unit is selected based on the input unit is come defeated
Go out and control signal, the tubular reactor system operation of control continuous flow；Wherein, described control unit includes：
Multigroup feed control device, every group of feed control device connects a head tank, for controlling each reaction solution
Flow velocity and flow；
Mixed control apparatus, for controlling the rotating speed of the servo motor；
Pre-heating control device, including preheating temperature detection device and preheating medium control device, the preheating temperature detection
Device is used to detect the temperature of preheated solution in preheating device tube side, and the preheating medium control device is used for according to the temperature control
The temperature and flow velocity of pre- thermal medium in preheating device shell side processed；
Reaction Control Assembly is controlled including reaction condition detection device, reaction stream velocity control device and heat medium and is filled
It puts, the reaction condition detection device includes temperature instrument, pressure instrumentation and flow rate detection instrument, anti-for measuring
Temperature, pressure and flow speed data that should be in pipe, the reaction stream velocity control device be used for according to the flow speed data in reaction tube
Reactant flow velocity is controlled, the heating medium control device is used to control reactor according to the temperature and pressure data in reaction tube
The temperature and flow velocity of heat medium inside shell side.
The continuous flow tubular reactor system and reaction control system of the present invention, has the following advantages that：
(1) by setting mixing arrangement, a variety of reaction solutions is sufficiently mixed, improve reaction efficiency.
(2) by setting preheating device, mixed reaction solution is made to heat up in advance before entering the reactor, into reaction
Reach reaction temperature after device as early as possible, improve reaction efficiency.
(3) reaction unit uses continuous flow pipeline, and continuous flow pipeline is connected by baffling bobbin carriage, substantially reduces adjacent anti-
The distance between should manage, the length of unit volume reaction tubes is made to increase significantly, under conditions of similary chemical reaction is met, this
The volume and space smaller, production cost of invention are lower.
(4) reaction tube is wound in the shape of a spiral, and reactant makes reactant low along the spiral tangential motion of helically coiled
High reynolds number is obtained under flow condition, greatly improves turbulence effects, remains to uninterruptedly mix in continuous flowing reactive；In addition,
Wound form reaction tube group is integrally in spring form, can pass thermogenetic thermal stress with elimination reaction, will not conduct thermal stress to pipe
Plate end substantially increases the service life of equipment.
(5) reaction control system detects the reaction condition of reaction system links in real time, and makes accurate feedback and adjust
Section, the accurate every reaction condition controlled in reaction system.
Description of the drawings
Fig. 1 is the overall structure diagram of the continuous flow tubular reactor system of the present invention；
Fig. 2 is the structure diagram of the reaction unit of the continuous flow tubular reactor system of the present invention；
Fig. 3 is the functional block diagram of the continuous flow pipe reaction control system of the present invention.
Specific embodiment
Below in conjunction with the attached drawing in the embodiment of the present invention, the technical solution in the embodiment of the present invention is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, those of ordinary skill in the art are obtained every other without making creative work
Embodiment shall fall within the protection scope of the present invention.
Embodiment 1：
As shown in Figs. 1-2, the continuous flow tubular reactor system of the present embodiment, including be sequentially communicated feed arrangement 1, mixing
Device 2, preheating device 3 and reaction unit 4.
Wherein, feed arrangement 1 includes multigroup sequentially connected head tank 10, feed pump 11 and flow controller 12, each
For containing a kind of reaction solution, flow controller 12 is used to control the feed pump 11 from the head tank 10 head tank 10
With given pace abstraction reaction solution.
Agitating paddle 20 is installed, agitating paddle 20 is driven by servo motor 21, for will be from the head tank in mixing arrangement 2
The reaction solution extracted in 10 is mixed, and obtains mixed solution.
Preheating device 3 includes preheating tube side 30 and preheating shell side 31, preheats tube side 30 for circulating from the mixing arrangement 2
The mixed solution of importing, preheating shell side 31 are used for the pre- thermal medium to circulate for preheating reactant.
Reaction unit 4 includes reactor shell 40, and the lower part of reactor shell 40 is provided with shell side inlet 41, reactor enclosure
The top of body 40 is provided with shell-side outlet 42, and the heating circulated for heating reactant is used for inside the shell side of reactor shell 40
Medium；The upper and lower ends of reactor shell 40 are respectively connected with tube sheet 43 and communication apparatus, and reactor shell 40 is internally provided with
For more reaction tubes 44 of the reactant that circulates, the upper and lower ends of every reaction tube 44 pass through and are fixedly connected on the tube sheet 43
On, all reaction tubes 44 are sequentially communicated by the communication apparatus.
Further, it is provided with 45 He of reactant entrance on the communication apparatus of 40 lower end of reactor shell in the present embodiment
Reactant exit 46, the reactant entrance 45 connect the preheating device 3, and the reactant exit 46 connects products pot.
Further, it is provided with temperature instrument on the communication apparatus of 40 upper end of reactor shell in the present embodiment
47th, pressure instrumentation 48 and flow rate detection instrument 49, for measuring temperature, pressure and the flow speed data in the reaction tube.
Further, the communication apparatus in the present embodiment uses baffling bobbin carriage 5, is provided on the baffling bobbin carriage 5 multiple
Adjacent two reaction tubes, 44 corresponding baffling slot 50, all reaction tubes 44 pass through baffling in 44 communication direction of reaction tube
Baffling slot 50 on bobbin carriage 5 is sequentially communicated.Adjacent reaction tube is connected using baffling slot, can greatly reduce adjacent reaction pipe it
Between distance, the length of unit volume reaction tubes is made to increase significantly, under conditions of similary chemical reaction is met, the present embodiment
In the volume of reaction unit and space smaller.
Further, more reaction tubes 44 in the present embodiment are wound with certain helix angle and set, and it is anti-to form wound form
Should pipe group, wound form reaction tube group winds in the shape of a spiral, and reactant makes reactant along the spiral tangential motion of helically coiled
High reynolds number is obtained in low flow velocity, greatly improves turbulence effects, remains to uninterruptedly mix in continuous flowing reactive；Separately
Outside, wound form reaction tube group is integrally in spring form, can pass thermogenetic thermal stress with elimination reaction, thermal stress will not be conducted to
Tube sheet end substantially increases the service life of equipment.
Embodiment 2：
Present embodiment discloses a kind of continuous flow pipe reaction control system, including input unit 6 and control unit 7, institute
Input unit 6 is stated for selecting preset reaction pattern, the reaction mould that described control unit 7 is selected based on the input unit 6
Formula exports control signal, control continuous flow tubular reactor system operation；Wherein, described control unit 7 includes：
Multigroup feed control device 70, every group of feed control device 70 connect a head tank 10, for controlling each anti-
Answer the flow velocity and flow of solution；
Mixed control apparatus 71, for controlling the rotating speed of the servo motor 21；
Pre-heating control device 72, including preheating temperature detection device 73 and preheating medium control device 74, the preheating temperature
Degree detection device 73 is used to detect the temperature that preheating device 3 preheats preheated solution in tube side 30, the preheating medium control device
74 are used for the temperature and flow velocity that preheating device 3 are controlled to preheat pre- thermal medium in shell side 31 according to the temperature；
Reaction Control Assembly 75, including reaction condition detection device 76, reaction stream velocity control device 77 and heat medium
Control device 78, the reaction condition detection device 76 include temperature instrument 47, pressure instrumentation 48 and flow rate detection
Instrument 49, for measuring temperature, pressure and the flow speed data in reaction tube 44, the reaction stream velocity control device 77 is used for root
Reactant flow velocity is controlled according to the flow speed data in reaction tube 44, the heating medium control device 78 is used for according in reaction tube 44
Temperature and pressure data control reactor shell side inside heat medium temperature and flow velocity.
Further, input unit 6 selects preset reaction pattern in the present embodiment, and the preset reaction pattern includes
The preset flow rate and preset flow of each reaction solution preheat the preset temperature of preheated solution in tube side 30, in preheating shell side 31
The preset temperature and preset flow rate of pre- thermal medium, preset temperature, preset pressure and preset flow rate in reaction tube 44, reactor enclosure
The preset temperature and preset flow rate of heat medium inside journey.Those skilled in the art can according to the content of the present embodiment, by
Software and necessary general hardware platform, to realize preset reaction pattern in the present embodiment.
At runtime, according to the default reaction pattern that input unit 6 selects, control is anti-for the reaction control system of the present embodiment
Answer the feed arrangement 1 in system will be in the plurality of raw materials solution injection mixing arrangement 2 in multiple head tanks 10；Mixing arrangement 2 makes
After material solution is sufficiently mixed, mixed solution enters in preheating device 3；Pre-heating control device 73 detects 3 economizer bank of preheating device
The temperature of preheated solution in journey 30, and according to the temperature and stream of pre- thermal medium in the temperature control preheating shell side 31 of preheating device 3
Speed；After the completion of preheating, reaction solution is entered by continuous flow pipeline in reaction unit 4, and Reaction Control Assembly detects and feeds back control
The stabilization of reaction condition processed.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, it is noted that for this
For the those of ordinary skill of technical field, under the premise of the application principle is not departed from, several improvement and profit can also be made
Decorations, all within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on are regarded as being included in this
Within the protection domain of invention.
Claims (3)
1. a kind of continuous flow tubular reactor system, it is characterised in that：Including the feed arrangement, mixing arrangement, preheating being sequentially communicated
Device and reaction unit,
The feed arrangement includes multigroup sequentially connected head tank, feed pump and flow controller, and each head tank is used
In containing a kind of reaction solution, the flow controller is used to that the feed pump to be controlled to take out with given pace from the head tank
Take reaction solution；
Agitating paddle is installed, the agitating paddle is driven by servo motor, for will be from the head tank in the mixing arrangement
The reaction solution of extraction is mixed, and obtains mixed solution；
The preheating device includes preheating tube side and preheating shell side, and the preheating tube side imports for circulating from the mixing arrangement
Mixed solution, the preheating shell side is for circulating to preheat the pre- thermal medium of reactant；
The reaction unit includes reactor shell, and the lower part of the reactor shell is provided with shell side inlet, the reactor
The top of housing is provided with shell-side outlet, and the heating circulated for heating reactant is used for inside the shell side of the reactor shell
Medium；The upper and lower ends of the reactor shell are respectively connected with tube sheet and communication apparatus, the inside setting of the reactor shell
The reaction tube group of circulation reactant is useful for, the reaction tube group includes more reaction tubes, and the upper and lower ends of every reaction tube are worn
Cross and be fixedly connected on the tube sheet, all reaction tubes are sequentially communicated by the communication apparatus, the more reaction tubes with
Certain helix angle winding setting；The communication apparatus uses baffling bobbin carriage, be provided on the baffling bobbin carriage it is multiple with it is described
The adjacent corresponding baffling slot of two reaction tubes, all reaction tubes pass through the baffling slot on baffling bobbin carriage in reaction tube communication direction
It is sequentially communicated, temperature instrument, pressure instrumentation and flow velocity is provided on the communication apparatus of the reactor shell upper end
Instrument is detected, for measuring temperature, pressure and the flow speed data in the reaction tube.
2. a kind of continuous flow tubular reactor system as described in claim 1, it is characterised in that：The reactor shell lower end
Reactant entrance and reactant exit are provided on communication apparatus, the reactant entrance connects the preheating device, described anti-
Answer object outlet products pot.
3. a kind of be used to that the continuous flow pipe reaction of continuous flow tubular reactor system as claimed in claim 1 or 2 to be controlled to control
System, it is characterised in that：Including input unit and control unit, the input unit is used to select preset reaction pattern, institute
The reaction pattern that control unit selected based on the input unit is stated to export control signal, controls continuous flow tubular reactor system
Operation；Wherein, described control unit includes：
Multigroup feed control device, every group of feed control device connects a head tank, for controlling the stream of each reaction solution
Speed and flow；
Mixed control apparatus, for controlling the rotating speed of the servo motor；
Pre-heating control device, including preheating temperature detection device and preheating medium control device, the preheating temperature detection device
For detecting the temperature of preheated solution in preheating device tube side, the preheating medium control device is used to be controlled according to the temperature pre-
The temperature and flow velocity of pre- thermal medium in thermal shell side；
Reaction Control Assembly, including reaction condition detection device, reaction stream velocity control device and heating medium control device, institute
It states reaction condition detection device and includes temperature instrument, pressure instrumentation and flow rate detection instrument, for measuring reaction tube
Interior temperature, pressure and flow speed data, the reaction stream velocity control device are used to be controlled according to the flow speed data in reaction tube
Reactant flow velocity, the heating medium control device are used to control reactor shell side according to the temperature and pressure data in reaction tube
The temperature and flow velocity of internal heat medium.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710433895.1A CN107051366B (en) | 2017-06-09 | 2017-06-09 | A kind of continuous flow tubular reactor system and reaction control system |
| RU2019142135A RU2726178C1 (en) | 2017-06-09 | 2018-05-28 | Pipe flow deflection chamber, continuous flow reactor and continuous flow reaction system with control system |
| EP18813078.5A EP3616785B1 (en) | 2017-06-09 | 2018-05-28 | Baffling tube box, continuous flow reactor, continuous flow reaction system and control system |
| US16/616,447 US10807065B2 (en) | 2017-06-09 | 2018-05-28 | Baffling tube box, continuous flow reactor, continuous flow reaction system and control system |
| PCT/CN2018/088680 WO2018223862A1 (en) | 2017-06-09 | 2018-05-28 | Baffling tube box, continuous flow reactor, continuous flow reaction system and control system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710433895.1A CN107051366B (en) | 2017-06-09 | 2017-06-09 | A kind of continuous flow tubular reactor system and reaction control system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107051366A CN107051366A (en) | 2017-08-18 |
| CN107051366B true CN107051366B (en) | 2018-06-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710433895.1A Active CN107051366B (en) | 2017-06-09 | 2017-06-09 | A kind of continuous flow tubular reactor system and reaction control system |
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| CN (1) | CN107051366B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3616785B1 (en) | 2017-06-09 | 2022-01-12 | Shandong Nuowei Pharmaceutical Fluid System Co., Ltd | Baffling tube box, continuous flow reactor, continuous flow reaction system and control system |
| CN109503522A (en) * | 2018-12-27 | 2019-03-22 | 江苏联昇化学有限公司 | A kind of tubular reactor of 3- hydroxyl tetrahydrofuran |
| CN112495317B (en) * | 2020-11-10 | 2022-08-16 | 中钢集团马鞍山矿山研究总院股份有限公司 | Method for continuously preparing carbon aerogel precursor |
| CN114534655A (en) * | 2022-02-23 | 2022-05-27 | 厦门芯曙光科技有限公司 | Flow chemical automation experiment system and control method thereof |
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|---|---|---|---|---|
| CN1832979A (en) * | 2003-06-06 | 2006-09-13 | 伊斯曼化学公司 | Polyester process using a pipe reactor |
| CN104258796A (en) * | 2014-10-13 | 2015-01-07 | 南京工业大学 | Novel high-flux multilayer spiral winding pipe micro-channel reactor |
| CN106699526A (en) * | 2016-11-07 | 2017-05-24 | 常州大学 | Method of preparing 2,4-dichlorobenzaldehyde through continuous oxidation of 2,4-dichlorotoluene |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002072254A2 (en) * | 2001-03-12 | 2002-09-19 | Bhr Group Limited | Reactor apparatus and mixing inlet and methods |
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2017
- 2017-06-09 CN CN201710433895.1A patent/CN107051366B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1832979A (en) * | 2003-06-06 | 2006-09-13 | 伊斯曼化学公司 | Polyester process using a pipe reactor |
| CN104258796A (en) * | 2014-10-13 | 2015-01-07 | 南京工业大学 | Novel high-flux multilayer spiral winding pipe micro-channel reactor |
| CN106699526A (en) * | 2016-11-07 | 2017-05-24 | 常州大学 | Method of preparing 2,4-dichlorobenzaldehyde through continuous oxidation of 2,4-dichlorotoluene |
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| CN107051366A (en) | 2017-08-18 |
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