CN107041857A - A kind of smoothing wrinkle freckle-removing mask and preparation method thereof - Google Patents
A kind of smoothing wrinkle freckle-removing mask and preparation method thereof Download PDFInfo
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- CN107041857A CN107041857A CN201710065682.8A CN201710065682A CN107041857A CN 107041857 A CN107041857 A CN 107041857A CN 201710065682 A CN201710065682 A CN 201710065682A CN 107041857 A CN107041857 A CN 107041857A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The present invention discloses a kind of smoothing wrinkle freckle-removing mask, is prepared from by dandelion, mulberry leaf, persimmon leaves, tassel flower, phoenix-tail fern, common bombax flower;The smoothing wrinkle freckle-removing mask selection pure plant that the present invention is provided is raw material, and Synergistic, long-term use can improve relaxation and the microgroove of facial skin, reducing facial colour spot, there is provided full effect Nutritional Nursing Care, smoothing wrinkle nti-freckle, pore refining, strengthens skin elasticity, makes skin full, flat;In addition all kinds of auxiliary materials are additionally added, makes the facial mask of the present invention while smoothing wrinkle nti-freckle, is also equipped with the multi-efficiencies such as skin-moisturizing, skin, whitening anti-acne, Peppermint Extract;The present invention provides the facial mask of a variety of formulations, carries, easy to use, meets the different demands of many people;Therapeutic effect is obvious, short treating period;With low cost and raw material sources are extensively, preparation method is simple, has broad application prospects.
Description
Technical field
The present invention relates to technical field of skin care, and in particular to a kind of smoothing wrinkle freckle-removing mask and preparation method thereof.
Background technology
It as the saying goes " people leans on the whole body skin by a face, tree ", for modern for beautiful cognition, the nursing of facial skin
Progressively brought into schedule with maintenance, be vast crowd opposite portion maintenance of liking to be beautiful in particular for the wrinkle and color spot of skin of face
Emphasis.
Modern medicine thinks that wrinkle is produced mainly due to natural aging and the light aging of skin, and its mechanism includes corium
Connection with epidermis is thinning, the reduction of laminin, the loss of collagen, Gas bases glucan and subcutaneous fat, also gravity and
Muscle, the lasting motion in joint.In addition, other influences factor includes:Internal factor such as race, inherent cause, hormone, oxidation pressure
Power, systemic disease etc. and external factor such as temperature, wind, air pollution, drink and smoking etc..Also result of study represents woman
Female's gestation and menopause are also relevant with the growth of facial wrinkles, it is believed that low estrogen may be because of the process of participation skin collagen reduction
Wrinkle is promoted to produce.
The traditional Chinese medical science thinks that the main cause of skin wrinkle includes:Naturally-aged, seven ends of love, six external factors which cause diseases invasion and attack, internal organs are contained
Decline, qi and blood dysfunction, passages through which vital energy circulates dysfunction, improper diet, work and rest is hindered, environmental factor is caused a disease.Common clinical syndrome differentiation
Have:Weakness of the spleen and the stomach, stagnation of the circulation of vital energy blood addiction and caused by liver and kidney deficiency.《Ling Shu Miraculous Pivot or Divine Axis perverse trend cacosplanchnia shape》Say:" twelve regular channels, 365 networks, its
Vim and vigour all in face and walk idle running." have again " Outer Appearance from the Inside ".Qi and blood can not go up flourish head, and moistening for muscle mistake is foster, skin
Skin loses moist, then wrinkle life.
There are significant progress and development in terms of smoothing wrinkle, be born and many advanced treatment methods, including medicine is controlled
Treat, Chemical peeling changes skin, Soft-tissue operation, botulinum toxin injection, physical therapy and the operation such as laser, ultrasonic wave, radio frequency, electric shock
Treatment etc..Removing the method for facial mask wrinkle of skin at present mainly has:(1)Ice electric wave draws skin;(2)The minimally invasive smoothing wrinkle of Korean style;(3)From
Body cell smoothing wrinkle;(4)Use anti-wrinkle mask.Although first three methods effect is substantially, operation risk is big, and price is high, and holds
Easily recurrence;4th kind of method, goes drawn grain film using simple, easily absorbs, but anti-wrinkle mask in the market also has many
Deficiency, contains chemical products mostly, and chemical products can cause the side effect of skin, and it is unfavorable to body to be used for a long time.
Chloasma is also known as " chloasma hepaticum ", " butterfly macules ", is the calm dermatoses of common pigments for betiding face.It is a kind of hair
The abnormal dermatoses of metabolism of pigment of face are born in, show as that symmetry that facial area size do not wait is yellowish-brown or light black spot
Piece, is divided on skin, and that comforts is not in the way.This sick men and women can occur, more with women.Its pathomechanism is complicated, interior point
This sick generation can be caused by secreting imbalance, ultraviolet irradiation, D&C, mental element etc..Chloasma is relevant with liver, kidney
And lack of proper care after one's birth, the dysfunction of the spleen in transport, qi and blood can not go up honor in face, also give birth to foxiness.In a word, this disease and liver,spleen,kidney three are dirty, especially with
Liver is in close relations.Chloasma hepaticum also known as blackish facial patch, show as the symptoms such as black, dark face, dusty complexion, face Shao-, chloasma hepaticum, blackspot of looking unfamiliar, are
A kind of multi-cause hyperpigmentary disorders, influence patient's appearance, serious psychological pressure are caused to it.But the pathogenic factor of chloasma and
Complicated mechanism, wherein irritability stasis, kidney water (sun) is not enough and blood stasis internal resistance is its most common card type, next to that spleen soil loses
It is empty.
Modern medicine believes that, chloasma chloasma hepaticum is due to the enhancing of lesions of patients position melanocyte activity, melanocyte and black
Plain corpusculum increases, and then shows color spot.Under pathological state, intradermal macrophage can swallow the melanin for being dropped into corium
Body, or calmness are degraded in dermis, or in the cell, and a part is through Lymph Node Metastasis.The generation of pigment and excretion disequilibrium,
And superfluous the part being gathered in epidermal cell, just form pigmentation.The excretion of melanin has two approach:One is from kidney
Interior excretion, another discharged through skin, i.e., melanin is transferred in keratoprotein, migrates to cuticula with epidermal growth, most
Renew afterwards with the cuticula cycle and come off.The method for the treatment of chloasma includes acupuncture and tuina-massage (such as local acupuncture, body acupuncture, cave at present
Position injection, cup, popular treatment for sunstroke by scraping the patient's neck, chest or back, massage, SHENQUE acupoint are sticked, sunken cord, imbedding needle, the ear acupuncture point etc.), external therapy (such as creams, facial mask, lotion,
Stifling side) and decoction for the treatment etc..But the effect of these treatment methods is less desirable, it is impossible to fundamentally treat chloasma, and
And also certain side effect.Therefore, a kind of material for preventing and treating chloasma chloasma hepaticum of highly effective and safe compeling as people is invented
It is essential and asks.
In recent years, facial mask is gradually by vast female consumer institute pro-gaze, and its main cause is to be covered in skin
On, skin can be made quickly to supplement nutrition and moisture required for skin, so that the effect of skin nursing has been reached, along with wide
The guided consumption idea of marketing is accused, and then causes facial mask to turn into one of commodity most popular on Cosmetic Market.Current city
Scene film is main based on box-packaged, and such product is main to cut required shape of face by non-woven fabrics, is subject to the solution of skin care maintenance,
It is subject to packed, last mounted box sale again, is significantly increased with cost needed for this made facial mask out, so that above market
Film finished product expensive and it can be in any more;Secondly, although with certain skincare effect when using, it is but if long-term
Use, skin can form dependence to it, an amount is disabled, i.e., can rebounded, or even even worse;And this facial mask is due to the addition of chemistry
Additive, most of facial masks can there are chemical residue after, have certain side effect to skin.
As effect of the Chinese Traditional Medicine beauty in modern beauty is accepted by increasing people, face mask of traditional Chinese medicine conduct
A kind of cosmetics and skincare product arises at the historic moment, and obtains liking for people with its hyposensitivity and low side effect.But it is existing in
Powder film is big multi-functional single, such as MASQUE APAISANT HYDRATANT can supplement moisture content for skin of face, so that skin becomes delicate, and desalinates
Microgroove, but the color spot, acne to pigmentation formation but produce little effect;Facial masks for whitening faces and removing spots can skin whitening, dispel color
Spot, but without replenishing water and preserving moisture, the function of anti-wrinkle.Therefore, possess smoothing wrinkle nti-freckle, skin-moisturizing, skin, whitening anti-acne etc. multi-functional
Compound face mask of traditional Chinese medicine, with good market prospects.
The content of the invention
It is contemplated that inventing a kind of smoothing wrinkle freckle-removing mask.The facial mask is effectively reduced facial wrinkles and dispelling stain, has
Imitate Small side effects, the advantage of instant effect.
For achieving the above object, technical scheme is as follows:
The smoothing wrinkle freckle-removing mask of the present invention, is made up of the raw material of following parts by weight:
10-30 parts of dandelion, 10-25 parts of mulberry leaf, 8-35 parts of persimmon leaves, 5-20 parts of tassel flower, 7-25 parts of phoenix-tail fern, common bombax flower 8-
15 parts.
Preferably, it is made up of the raw material of following parts by weight:
20-25 parts of dandelion, 15-20 parts of mulberry leaf, 15-22 parts of persimmon leaves, 10-15 parts of tassel flower, 10-15 parts of phoenix-tail fern, kapok
10-12 parts of flower.
The source for the Chinese medicine that the present invention is used and effect are as follows:
Dandelion, is feverfew dandelion Taraxacum mongolicum Hand.-Mazz., alkali ground dandelion
Taraxacum sinicum Kitag. or the drying herb for belonging to several plants together.It is bitter, sweet, tremble with fear.Can be clearing heat and detoxicating, Sweeling-eliminating medicine powder
Knot, inducing diuresis for treating strangurtia.For furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharyngalgia, lung carbuncle, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.
Mulberry leaf, are moraceae plants mulberry Morus alba L. dried leaf.Sweet, hardship, trembles with fear.Can dispelling wind and heat from the body, clearing away the lungheat and moisturizing,
Clear liver and improve vision.For anemopyretic cold, lung-heat type cough, dizziness headache, hot eyes is dim-sighted.
Persimmon leaves, latin name Diospyros kaki Thunb., are the blade of Ebenaceae plant persimmon.Hardship, trembles with fear.Can cough-relieving determine
Breathe heavily, promote the production of body fluid to quench thirst, promoting blood circulation and hemostasis, main cough and asthma is quenched one's thirst and various internal haemorrhages, earns sore.
Tassel flower, is composite family tassel flower platymiscium tassel flower Emilia sonchifolia(L.)DC. drying herb.
Hardship, it is cool.Can be clearing heat and detoxicating, eliminating stasis to subdue swelling.The infection of the upper respiratory tract, abscess of throat, canker sore, pneumonia, chordapsus is bacillary
Dysentery, urinary system infection contamination, orchitis, mastitis, furuncle sore, skin eczema, bruises and sprains.
Phoenix-tail fern, is Pteridaceae plant phoenix-tail fern Pteris multifida Poir. herb.Light, slight bitter, it is cool.Can
Clearing heat and promoting diuresis, detoxify stop dysentery, cooling blood and hemostasis.For dysentery, gastroenteritis, hepatitis, urinary infection, cat fever, abscess of throat,
Leukorrhea, uterine bleeding, pesticide poisoning;Traumatism and bleeding, burn and scald are controlled in external application.
Common bombax flower, is the flower of Bombacaceae plant kapok.It is sweet, it is light, it is cool.Can clearing heat and promoting diuresis, removing toxic substances hemostasis.Main diarrhea, dysentery,
Hemoptysis, haematemesis, metrorrhagia, metal-inflicted wound bleeding, sore, eczema.
It is a further object of the present invention to provide the preparation method of the active component of the smoothing wrinkle freckle-removing mask, this method is water
Carry or the ethanol extraction of 40-70% concentration expressed in percentage by volumes is prepared from.
Scheme one:Extracting in water 2-3 times after whole raw material, mixing is taken, each amount of water is equivalent to raw material gross weight
6-12 times, each extraction time be 1-3 hour, merge extract solution, filter, relative density is when filtrate is concentrated into 70-80 DEG C
1.15-1.20 clear cream, produces active component.
Scheme two:Whole raw material are taken, are extracted 2-3 times with 40-70% alcohol refluxs after mixing, each ethanol consumption is medicine
4-10 times of material total amount, extraction time is 1-4 hours, merges extract solution, filtering, relative density when filtrate is concentrated into 70-80 DEG C
For 1.15-1.20 clear cream, active component is produced.
Scheme three:Extracting in water 2-3 times after whole raw material, mixing is taken, each amount of water is equivalent to medicinal material gross weight
6-12 times, each extraction time is 1-3 hours, merges extract solution, is filtered, relative density is when filtrate is concentrated into 70-80 DEG C
1.15-1.20 clear cream, adds ethanol, and it is 40-60% to make alcohol content, stands 12-24 hours, and filtering, filtrate is concentrated into 70-80
DEG C when relative density be 1.10-1.25 medicinal extract, produce active component.
Smoothing wrinkle freckle-removing mask of the present invention, can also be made different doses with pharmaceutically acceptable carrier combination
The facial mask of type, such as tear-pull facial mask, mud cream type facial mask, creams type facial mask, gel facial mask, mounted facial mask
The pharmaceutically acceptable carrier of the present invention includes but is not limited to following:
Thickener:Carbomer, xanthans, hydroxyethyl cellulose, acrylic acid, microcrystalline cellulose, alkylol acrylamide acid esters cross-linked polymeric
Thing etc..
Adsorbent:Activated carbon, diatomite etc..
Solid powder:Mica, kaolin, silica gel, clay etc..
Surfactant:Sodium methyl cocoyl taurate, APG.
High molecular polymer:Cellulose, xanthan gum etc..
NMF:Glycerine, sorbierite, propane diols, butanediol, Sodium Hyaluronate, glycine betaine, trehalose, polyethylene glycol etc..
Skin sense conditioner:Beta glucan, biological carbohydrate gum -1, Chondrus crispus, Scleroglucan etc..
Preservative:Benzoic acid, sorbic acid, methyl esters, ethyl ester, propyl ester etc..
Emulsifying agent:Tristerin, Glyceryl stearate citrate, sucrose, sucrose palmitate etc..
Method 1:Tear-pull facial mask
Take scheme one one of to the gained active component of scheme three, add tear-pull facial mask and often use auxiliary material, routinely producer legal system
It is standby to obtain tear-pull facial mask of the present invention.
Above-mentioned tear-pull facial mask often includes one of thickener, adsorbent, NMF, preservative or whole with auxiliary material.
Method 2:Mud cream type facial mask
Take scheme one one of to the gained active component of scheme three, add mud cream type facial mask and often use auxiliary material, routinely producer legal system
It is standby to obtain mud cream type facial mask of the present invention.
Above-mentioned mud cream type facial mask often includes solid powder with auxiliary material, high molecular polymer, surfactant, NMF, anti-
One of rotten agent is whole.
Method 3:Creams type facial mask
Take scheme one one of to the gained active component of scheme three, add creams type facial mask and often use auxiliary material, routinely producer legal system
It is standby to obtain creams type facial mask of the present invention.
Above-mentioned creams type facial mask often includes one of emulsifying agent, NMF, preservative or whole with auxiliary material.
Method 4:Gel facial mask
Take scheme one one of to the gained active component of scheme three, add gel facial mask and often use auxiliary material, routinely prepared by production method
Obtain gel facial mask of the present invention.
Above-mentioned gel facial mask often includes one of NMF, thickener, preservative or whole with auxiliary material.
Method 5:Mounted facial mask
Take scheme one one of to the gained active component of scheme three, add mounted facial mask and often use auxiliary material, routinely prepared by production method
Obtain mounted facial mask of the invention.
Above-mentioned mounted facial mask often includes one of thickener, NMF, skin sense conditioner, preservative or whole with auxiliary material.
The present invention also provides another preparation method of described smoothing wrinkle freckle-removing mask, comprises the following steps:By raw material
Crush as 50-100 mesh powders, the one kind added after being well mixed in water, honey, milk is tuned into pasty state, you can.
The formula of the present invention is rationally innovated, and dandelion is clearing heat and detoxicating, rich in anti-oxidation active substance, there is good wrinkle resistant effect
Really, and pigmentation and development can be reduced;Mulberry leaf clearing away the lungheat and moisturizing, alleviates excited, improvement organism metabolism, reduces or eliminates body
Interior lipofuscin;Persimmon leaves promoting blood circulation and hemostasis, anti-inflammation, with whitening, nti-freckle, anti-ageing medical health care function of waiting for a long time;Tassel flower is clear
Thermal detoxification, eliminating stasis to subdue swelling, purging intense heat nourishing the stomach promotes skin of face toxin expelling;Phoenix-tail fern clearing heat and promoting diuresis, hemostasia and promoting granulation improves skin and exempted from
Epidemic disease power;Common bombax flower removing toxic substances hemostasis, with convergence, analgesic activity, reduces pore.A variety of natural traditional Chinese medicine extracts collaborations increase above
Effect, has effects that nti-freckle, smoothing wrinkle.
Beneficial effects of the present invention are:
(1)The smoothing wrinkle freckle-removing mask selection pure plant that the present invention is provided is raw material, and dandelion is rich in anti-oxidation active substance,
There is good wrinkle-proof effect, and pigmentation and development can be reduced;Mulberry leaf improve organism metabolism, reduce or eliminate internal fat brown
Matter;Persimmon leaves have whitening, nti-freckle, anti-ageing medical health care function of waiting for a long time;Tassel flower is clearing heat and detoxicating, promotes skin of face toxin expelling;
Phoenix-tail fern hemostasia and promoting granulation, improves cutaneous immunisation power;Common bombax flower has convergence, analgesic activity, reduces skin pore.The a variety of days of the above
Right Chinese medical extract Synergistic, relaxation and the microgroove of facial skin can be improved by being used for a long time with this obtained facial mask, reduce face
Portion's color spot strengthens skin elasticity, makes skin full, flat there is provided full effect Nutritional Nursing Care, smoothing wrinkle nti-freckle, pore refining;
(2)The smoothing wrinkle freckle-removing mask that the present invention is provided is to treating butterfly type color spot total effective rate up to 94.5%;Treatment face top type color
Spot total effective rate is up to 94.7%;Treatment face bottom type color spot total effective rate is up to 91.7%;General hair style color spot total effective rate is treated to reach
96.6%;Forehead line total effective rate is treated up to 90.7%;Crow's feet total effective rate is treated up to 91.7%;Treat glabella line total effective rate
Up to 94.7%;Bridge of the nose line total effective rate is treated up to 90.9%;Illustrate the smoothing wrinkle freckle-removing mask of the present invention to treating all kinds of color spots and disappearing
Wrinkle has remarkable result;
(3)The smoothing wrinkle freckle-removing mask that the present invention is provided is such as sweet except rich in natural plant active component, being additionally added all kinds of auxiliary materials
Oil, diatomite etc., make the smoothing wrinkle freckle-removing mask of the present invention can be with smoothing wrinkle nti-freckle while, are also equipped with skin-moisturizing, skin, whitening and dispel
The multi-efficiencies such as acne, Peppermint Extract, and Small side effects, can meet the complicated crowd demand of skin quality;
(4)The smoothing wrinkle freckle-removing mask that the present invention is provided can be made into the facial mask of various formulations, carry, easy to use, meet numerous people
The different demands of group;Therapeutic effect is obvious, short treating period;With low cost and raw material sources are extensively, preparation method is simple, has
Wide application prospect.
Embodiment
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are to be used to illustrate
The present invention rather than limitation of the present invention.The present invention is belonged to according to the simple modifications that the essence of the present invention is carried out to the present invention
Claimed scope.Unless otherwise indicated, the percentage of the amount of alcohol in the present invention is percentage by volume, and v/v represents solution
Volume ratio.
The tear-pull facial mask of embodiment 1
Weigh dandelion 10kg, mulberry leaf 10kg, persimmon leaves 8kg, tassel flower 5kg, phoenix-tail fern 7kg, common bombax flower 8kg.Add after mixing
Water is extracted 3 times, and three amount of water are respectively 12 times of medicinal material gross weight, 10 times, 6 times, and three extraction times are respectively 3 small
When, 2 hours, 1 hour, merge extract solution, filtering, when filtrate is concentrated into 70 DEG C relative density be 1.15 clear cream, in clear cream
Tear-pull facial mask auxiliary material carbomer, diatomite, glycerine, propane diols, sorbic acid are added, tear-pull facial mask is made according to a conventional method.
The tear-pull facial mask of embodiment 2
Weigh dandelion 12kg, mulberry leaf 11kg, persimmon leaves 10kg, tassel flower 6kg, phoenix-tail fern 8kg, common bombax flower 8kg.Used after mixing
40% alcohol reflux is extracted 3 times, and each ethanol consumption is respectively 10 times of medicinal material total amount, 8 times, 4 times, and extraction time difference 4 is small
When, 2 hours, 1 hour, merge extract solution, filtering, filtrate concentrate 70 DEG C when relative density be 1.15 clear cream, in clear cream plus
Enter tear-pull facial mask auxiliary material xanthans, acrylic acid, activated carbon, butanediol, glycine betaine, benzoic acid, be made according to a conventional method.
The mud cream type facial mask of embodiment 3
Weigh dandelion 14kg, mulberry leaf 12kg, persimmon leaves 11kg, tassel flower 7kg, phoenix-tail fern 8kg, common bombax flower 9kg.After mixing
Extracting in water 2 times, three amount of water are respectively equivalent to 12 times of medicinal material gross weight, 10 times, and each extraction time difference 3 is small
When, 2 hours, merge extract solution, filtering, when filtrate is concentrated into 70 DEG C relative density be 1.15 clear cream, add ethanol, make to contain
Alcohol amount is 40%, stands 12 hours, filtering, and filtrate is concentrated into the medicinal extract that relative density when filtrate is concentrated into 70 DEG C is 1.10,
Mud cream type facial mask auxiliary material mica, clay, sodium methyl cocoyl taurate, xanthan gum, trehalose, poly- second two are added in medicinal extract
Alcohol, methyl esters, are made mud cream type facial mask according to a conventional method.
The mud cream type facial mask of embodiment 4
Weigh dandelion 15kg, mulberry leaf 14kg, persimmon leaves 12kg, tassel flower 8kg, phoenix-tail fern 9kg, common bombax flower 9kg.Add after mixing
Water is extracted 2 times, and each amount of water is respectively 10 times of medicinal material gross weight, 6 times, and each extraction time is respectively 2 hours, 1 small
When, merge extract solution, filter, relative density is 1.18 clear cream when filtrate is concentrated into 73 DEG C, mud cream type face is added in clear cream
Film auxiliary material kaolin, silica gel, APG class, cellulose, butanediol, ethyl ester, are made mud cream type facial mask according to a conventional method.
The creams type facial mask of embodiment 5
Weigh dandelion 16kg, mulberry leaf 14kg, persimmon leaves 14kg, tassel flower 9kg, phoenix-tail fern 10kg, common bombax flower 10kg.After mixing
Extracted 2 times with alcohol reflux, each concentration of alcohol is respectively 70%, 50%, and each ethanol consumption is respectively the 10 of medicinal material total amount
Again, 7 times, extraction time is respectively 4 hours, 2 hours, merges extract solution, is filtered, relative density is when filtrate is concentrated into 78 DEG C
1.18 clear cream, adds creams type facial mask auxiliary material glycerine, Sodium Hyaluronate, tristerin, glycerol stearate in clear cream
Ester citrate, benzoic acid, are made creams type facial mask according to a conventional method.
The creams type facial mask of embodiment 6
Weigh dandelion 18kg, mulberry leaf 15kg, persimmon leaves 15kg, tassel flower 10kg, phoenix-tail fern 10kg, common bombax flower 10kg.Mixing
Extracting in water 3 times afterwards, three amount of water are respectively equivalent to 12 times of medicinal material gross weight, 8 times, 6 times, each extraction time difference 3
Hour, 2 hours, 1 hour, merge extract solution, filter, relative density is 1.18 clear cream when filtrate is concentrated into 74 DEG C, is added
Ethanol, it is 50% to make alcohol content, stands 18 hours, filtering, and it is 1.15 that filtrate, which is concentrated into relative density when filtrate is concentrated into 77 DEG C,
Medicinal extract, creams type facial mask auxiliary material sucrose, sucrose palmitate, sorbierite, polyethylene glycol, propyl ester are added in medicinal extract, by normal
Creams type facial mask is made in rule method.
The gel facial mask of embodiment 7
Weigh dandelion 20kg, mulberry leaf 16kg, persimmon leaves 17kg, tassel flower 12kg, phoenix-tail fern 11kg, common bombax flower 11kg.Mixing
Extracting in water 3 times afterwards, three amount of water are respectively 12 times of medicinal material gross weight, 10 times, 7 times, and three extraction times are respectively
3 hours, 2 hours, 1 hour, merge extract solution, filter, relative density is 1.20 clear cream when filtrate is concentrated into 80 DEG C, is added
Gel facial mask microcrystalline cellulose excipients, carbomer, Sodium Hyaluronate, glycerine, sorbic acid, are made gel facial mask according to a conventional method.
The gel facial mask of embodiment 8
Weigh dandelion 22kg, mulberry leaf 18kg, persimmon leaves 22kg, tassel flower 14kg, phoenix-tail fern 12kg, common bombax flower 12kg.Mixing
Extracted 2 times with alcohol reflux afterwards, each concentration of alcohol is respectively 60%, 40%, and each ethanol consumption is respectively the 10 of medicinal material total amount
Again, 6 times, extraction time is respectively 3 hours, 2 hours, merges extract solution, is filtered, relative density is when filtrate is concentrated into 80 DEG C
1.20 clear cream, added in clear cream gel facial mask microcrystalline cellulose excipients, alkylol acrylamide acid esters cross-linked polymer, propane diols,
Glycine betaine, benzoic acid, are made gel facial mask according to a conventional method.
The mounted facial mask of embodiment 9
Weigh dandelion 24kg, mulberry leaf 20kg, persimmon leaves 25kg, tassel flower 15kg, phoenix-tail fern 15kg, common bombax flower 12kg.Mixing
Extracting in water 2 times afterwards, each amount of water is respectively 10 times of medicinal material gross weight, 6 times, each extraction time is respectively 3 hours,
2 hours, merge extract solution, filter, relative density is 1.20 clear cream when filtrate is concentrated into 80 DEG C, adds ethanol, makes alcohol content
For 60%, stand 24 hours, filtering, relative density is 1.25 medicinal extract when filtrate is concentrated into 80 DEG C, in medicinal extract in add patch
Formula facial mask auxiliary material xanthans, microcrystalline cellulose, trehalose, beta glucan, biological carbohydrate gum -1, glycerine, propyl ester, according to a conventional method
Mounted facial mask is made.
The mounted facial mask of embodiment 10
Weigh dandelion 25kg, mulberry leaf 22kg, persimmon leaves 28kg, tassel flower 17kg, phoenix-tail fern 18kg, common bombax flower 14kg.Mixing
Extracted 2 times with alcohol reflux afterwards, each concentration of alcohol is respectively 60%, 50%, and each ethanol consumption is respectively the 8 of medicinal material total amount
Again, 4 times, extraction time is respectively 4 hours, 2 hours, merges extract solution, is filtered, relative density is when filtrate is concentrated into 78 DEG C
1.20 medicinal extract, added in medicinal extract mounted facial mask auxiliary material carbomer, alkylol acrylamide acid esters cross-linked polymer, Chondrus crispus,
Scleroglucan, sorbic acid, propane diols, butanediol, are made mounted facial mask according to a conventional method
The powder-type facial mask of embodiment 11
Dandelion 27kg, mulberry leaf 24kg, persimmon leaves 32kg, tassel flower 18kg, phoenix-tail fern 22kg, common bombax flower 14kg are weighed, is crushed
For 50 mesh powders, water and honey are added after being well mixed, pasty state is tuned into, you can.
The powder-type facial mask of embodiment 12
Dandelion 30kg, mulberry leaf 25kg, persimmon leaves 35kg, tassel flower 20kg, phoenix-tail fern 25kg, common bombax flower 15kg are weighed, is crushed
For 100 mesh powder, milk is added after being well mixed, pasty state is tuned into, you can.
Clinical test is summarized
First, to the therapeutic effect of color spot
1. research object observes 146 patients, male 32, women 114, age 22-65 Sui, course of disease 0.5-15;Butterfly
55, type, 38, face top type, 24, face bottom type, general hair style 29.
2. treatment method:Treated, used once within every 3 days, 30 using the mud cream type facial mask described in the embodiment of the present invention 3
It is a course for the treatment of;Exclude to allergy of the embodiment of the present invention, the gestational period and nursing period patient;Other cosmetics are disabled during treatment.
3. criterion of therapeutical effect and treatment results
3.1 criterions of therapeutical effect are examined according to the clinic of Dermatology Professional Committee of CAIM pigment group chloasma
Disconnected and curative effect(2003 revised drafts).
It is basic to cure:Naked eyes visual pigment spot area disappears>90%, color disappears substantially, and scoring declines index>0.8;
It is effective:Pigmented spots area disappears>60%, color is substantially thin out, and scoring declines index>0.5;
Effectively:Pigmented spots area disappears>30%, color is thin out, and scoring declines index>0.3;
It is invalid:Naked eyes visual pigment spot area disappears<30%, color change is not obvious, and scoring declines index<0.3.
4 treatment results
Its treatment results is shown in Table 1
Therapeutic effect of the table 1 to color spot
Color spot type | Be almost recovered/example | Effective/example | Effectively/example | Invalid/example | Total effective rate/% |
Butterfly type | 32 | 16 | 4 | 3 | 94.5 |
Face top type | 18 | 8 | 10 | 2 | 94.7 |
Face bottom type | 11 | 5 | 6 | 2 | 91.7 |
General hair style | 14 | 8 | 6 | 1 | 96.6 |
As shown in table 1, smoothing wrinkle freckle-removing mask of the invention is to treating butterfly type color spot total effective rate up to 94.5%;Treatment face top
Type color spot total effective rate is up to 94.7%;Treatment face bottom type color spot total effective rate is up to 91.7%;Treat general hair style color spot total effective rate
Up to 96.6%;Illustrate the smoothing wrinkle freckle-removing mask of the present invention has remarkable result to treating all kinds of color spots.
2nd, to the therapeutic effect of face skin wrinkle
1. research object observes 109 patients, male 21, women 88, age 27-56 Sui;Wherein forehead line 43, fish
Tail line 36, glabella line 19, bridge of the nose line 11.
2. treatment method:Treated, pasted using one within every 3 days, 30 using the mounted facial mask described in the embodiment of the present invention 10
It is a course for the treatment of;All patients exclude disease in the blood system, disease of cardiovascular system, disease of immune system, active hepatitis,
Diabetes and other serious medical diseases.Women performs the operation non-pregnancy period, menstrual period or nursing period;Other cosmetics are disabled during treatment
Product.
3. criterion of therapeutical effect and treatment results
3.1 criterion of therapeutical effect
It is basic to cure:Skin has compared with deep wrinkle significantly to shoal, and thin shallow wrinkle all disappears;
It is effective:Skin shoals compared with deep wrinkle, and thin shallow wrinkle disappears substantially;
Effectively:Wrinkle of skin has shoaled;
It is invalid:Wrinkle of skin is unchanged, or deepens.
4 treatment results
Its treatment results is shown in Table 2
Therapeutic effect of the table 2 to face skin wrinkle
Wrinkle type | Be almost recovered/example | Effective/example | Effectively/example | Invalid/example | Total effective rate/% |
Forehead line | 27 | 5 | 7 | 4 | 90.7 |
Crow's feet | 23 | 7 | 3 | 3 | 91.7 |
Glabella line | 9 | 8 | 1 | 1 | 94.7 |
Bridge of the nose line | 5 | 2 | 3 | 1 | 90.9 |
As shown in table 1, smoothing wrinkle freckle-removing mask of the invention is to treating forehead line total effective rate up to 90.7%;Treatment crow's feet always has
Efficiency is up to 91.7%;Glabella line total effective rate is treated up to 94.7%;Bridge of the nose line total effective rate is treated up to 90.9%;Illustrate the present invention's
Smoothing wrinkle freckle-removing mask has remarkable result to all kinds of wrinkles for treating skin of face.
Model case
Case 1:Open xx, female, 36 years old, teacher.
Main suit:There is butterfly type color spot in face for many years, and skin damaged boundary understands, no furfur, and patient is with Breast bilges frowsty about, easily
Agitation, menstrual flow is general, and color secretly has clot, and urine is yellow, with hyperplasia of mammary glands, tongue drop, the thin Huang of tongue, wiry and rolling pulse.Give this hair
The creams type facial mask of bright embodiment 5 is treated, and adheres to using daily, and a course for the treatment of rear face color spot substantially declines, and face is dark
Heavy to be improved, 1 month color spot large area of continual cure is disappeared, and complexion is become better and better, and no recurrence is paid a return visit after half a year.
Case 2:Old XX, female, 35 years old, office worker.
Main suit:Face begins with a little brown spot point and occurred the year before, and it does not give attention, and brown spot gradually increases
It is many;Menstrual cycle is normal, 4-6 days menstrual period, through measure on the low side, color it is dim, when folder stasis of blood block.Pass through fore udder distending pain, when have soreness and weakness of waist and knees,
It is difficult to fall asleep, and two is just normal.On inspection, patient has one's face covered with visible brown spot.Forehead, two cheeks and lip Zhou Juncheng patches.Tongue nature is light to be had
Petechia, tongue are thin white, uneven pulse.The gel facial mask for giving the embodiment of the present invention 7 is treated, and adheres to using daily, after a course for the treatment of
Menstrual flow recovers normal, and fore udder no longer distending pain of passing through, sleep also has improvement.Face foxiness starts to dissipate, and tongue nature is light red, weak pulse
String.One course for the treatment of of treatment is continued to strengthen, complexion is significantly improved, and no recurrence is paid a return visit after 1 year.
Case 3:King X, female, 32 years old, office worker.
Main suit:Worked for a long time before computer, irregular eating comes to occur face bottom type color spot for 2 years, and skin damaged boundary is clear
Chu, the premenstrual swollen breasts of patient, menstrual period ache of the spinal column, menstrual flow is general, and color secretly has clot, and tongue is red, and few tongue, arteries and veins carefully sinks.Give
The powder-type facial mask of the embodiment of the present invention 11 is treated, and using once, a course for the treatment of rear face color spot substantially declines within every three days,
Face is obscure to be improved, and color spot large area disappears after two courses for the treatment of of continual cure, and eumenorrhea pays a return visit no recurrence after 1 year.
Case 4:All XX, man, 40 years old, geomatics engineer.
Main suit:It is operated in the wild for a long time, forehead, crow's foot are more, wrinkle is deep, diet, irregular, tongue fur of sleeping
Thick, yellow, two is just normal.The tear-pull facial mask for giving the embodiment of the present invention 1 is treated, and is used once within every three days, a course for the treatment of
Rear face wrinkle has been reduced, and two courses for the treatment of of continual cure, deep wrinkle disappears substantially, and thin shallow wrinkle is wholly absent, turgor,
It is flat.Patient is continuing with the tear-pull facial mask of the embodiment of the present invention 1, is paid a return visit after 2 years, the substantially wrinkle-free line of patient facial region.
Case 5:Zhao X, female, 29 years old, performer.
Main suit:Long-term to carry out performance work, diet, sleep are irregular, and two is just abnormal.There is thin shallow wrinkle in 3 years preceding canthus
Line, in recent years crow's foot gradually increase.The powder-type facial mask for giving the embodiment of the present invention 12 is treated, and uses one within every three days
Secondary, crow's foot has been reduced after a course for the treatment of, and two courses for the treatment of of continual cure, wrinkle is wholly absent, and turgor is fine and smooth, pure white
It is glossy.Patient is continuing with the smoothing wrinkle freckle-removing mask of the embodiment of the present invention, is paid a return visit after 2 years, patient facial region is without wrinkle, color spot.
Case 6:Square XX, man, 51 years old, peasant.
Main suit:Long-term to carry out farm work, wrinkle is more everywhere for face, and cheeks have color spot, and irregular eating, tongue is red, few
Tongue, uneven pulse, two is just normal.The mounted facial mask for giving the embodiment of the present invention 9 is treated, and is used once within every three days, a course for the treatment of
Rear face wrinkle has been reduced, and color spot area reduces, and one course for the treatment of of continual cure, deep wrinkle disappears substantially, and thin shallow wrinkle is complete
Disappear, the substantially colorless spot of cheeks, turgor, ruddy, complexion improvement, patient continues per 5-7 days using once present invention implementation
The smoothing wrinkle freckle-removing mask of example.Paid a return visit after 1 year, the substantially wrinkle-free line of patient facial region.
Claims (8)
1. a kind of smoothing wrinkle freckle-removing mask, it is characterised in that be made up of the raw material of following parts by weight:10-30 parts of dandelion, mulberry leaf
10-25 parts, 8-35 parts of persimmon leaves, 5-20 parts of tassel flower, 7-25 parts of phoenix-tail fern, 8-15 parts of common bombax flower.
2. smoothing wrinkle freckle-removing mask as claimed in claim 1, it is characterised in that be made up of the raw material of following parts by weight:Dandelion
20-25 parts, 15-20 parts of mulberry leaf, 15-22 parts of persimmon leaves, 10-15 parts of tassel flower, 10-15 parts of phoenix-tail fern, 10-12 parts of common bombax flower.
3. smoothing wrinkle freckle-removing mask as claimed in claim 1 or 2, it is characterised in that its active component is to use water extraction or 40-
The ethanol of 70% concentration expressed in percentage by volume is extracted and is prepared from.
4. smoothing wrinkle freckle-removing mask as claimed in claim 3, it is characterised in that its active component is to be prepared by the following method
:Take extracting in water 2-3 times after whole raw material, mixing, each amount of water equivalent to 6-12 times of raw material gross weight,
Each extraction time is 1-3 hours, merges extract solution, is filtered, and relative density is 1.15-1.20 when filtrate is concentrated into 70-80 DEG C
Clear cream, produce active component.
5. smoothing wrinkle freckle-removing mask as claimed in claim 3, it is characterised in that its active component is to be prepared by the following method
:Whole raw material are taken, are extracted 2-3 times with 40-70% alcohol refluxs after mixing, each ethanol consumption is medicinal material total amount
4-10 times, extraction time is 1-4 hours, merges extract solution, is filtered, and relative density is 1.15- when filtrate is concentrated into 70-80 DEG C
1.20 clear cream, produces active component.
6. smoothing wrinkle freckle-removing mask as claimed in claim 3, it is characterised in that its active component is to be prepared by the following method
:Take extracting in water 2-3 times after whole raw material, mixing, each amount of water equivalent to 6-12 times of medicinal material gross weight,
Each extraction time is 1-3 hours, merges extract solution, is filtered, and relative density is 1.15-1.20 when filtrate is concentrated into 70-80 DEG C
Clear cream, add ethanol, make alcohol content be 40-60%, stand 12-24 hour, filter, filtrate is concentrated into relatively close at 70-80 DEG C
The medicinal extract for 1.10-1.25 is spent, active component is produced.
7. a kind of smoothing wrinkle freckle-removing mask, as the smoothing wrinkle freckle-removing mask described in claim 1 or 2 and pharmaceutically acceptable load
Body, which is prepared, to be formed.
8. smoothing wrinkle freckle-removing mask as claimed in claim 1 or 2, it is characterised in that be prepared by the following method and form:Will
It is 50-100 mesh powders that raw material, which are crushed, and the one kind added after being well mixed in water, honey, milk is tuned into pasty state, you can.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107898713A (en) * | 2017-12-29 | 2018-04-13 | 广州视域光学科技有限公司 | A kind of preparation method and application of whitening anti-aging Essence, whitening anti-aging hydrogel Essence |
CN109010212A (en) * | 2018-09-21 | 2018-12-18 | 张惠柳 | It is a kind of for preventing and treating the facial mask of subcutaneous fat tumor |
CN111728915A (en) * | 2020-08-10 | 2020-10-02 | 黑龙江天龙药业有限公司 | Membrane patch for improving neck wrinkles and preparation method thereof |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101411681A (en) * | 2008-11-21 | 2009-04-22 | 赵献民 | Chinese medicine whitening and spot-removing facemask powder and preparation method thereof |
CN104784368A (en) * | 2015-04-09 | 2015-07-22 | 李健 | Externally-used medicine composition for treating chloasma |
CN105168052A (en) * | 2015-09-16 | 2015-12-23 | 杨塞红 | Traditional Chinese medicine facial mask for treating acne and removing wrinkle |
CN105748372A (en) * | 2016-03-29 | 2016-07-13 | 孙大龙 | Persimmon leaf-containing emulsified type whitening cleaning cream |
CN106265444A (en) * | 2016-09-11 | 2017-01-04 | 佛山市顺德区宝铜金属科技有限公司 | A kind of freckle removing facial mask made of Chinese medicine |
-
2017
- 2017-02-06 CN CN201710065682.8A patent/CN107041857A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101411681A (en) * | 2008-11-21 | 2009-04-22 | 赵献民 | Chinese medicine whitening and spot-removing facemask powder and preparation method thereof |
CN104784368A (en) * | 2015-04-09 | 2015-07-22 | 李健 | Externally-used medicine composition for treating chloasma |
CN105168052A (en) * | 2015-09-16 | 2015-12-23 | 杨塞红 | Traditional Chinese medicine facial mask for treating acne and removing wrinkle |
CN105748372A (en) * | 2016-03-29 | 2016-07-13 | 孙大龙 | Persimmon leaf-containing emulsified type whitening cleaning cream |
CN106265444A (en) * | 2016-09-11 | 2017-01-04 | 佛山市顺德区宝铜金属科技有限公司 | A kind of freckle removing facial mask made of Chinese medicine |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107898713A (en) * | 2017-12-29 | 2018-04-13 | 广州视域光学科技有限公司 | A kind of preparation method and application of whitening anti-aging Essence, whitening anti-aging hydrogel Essence |
CN109010212A (en) * | 2018-09-21 | 2018-12-18 | 张惠柳 | It is a kind of for preventing and treating the facial mask of subcutaneous fat tumor |
CN111728915A (en) * | 2020-08-10 | 2020-10-02 | 黑龙江天龙药业有限公司 | Membrane patch for improving neck wrinkles and preparation method thereof |
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