CN107029184B - A kind of mangosteen turmeric product and its preparation method and application - Google Patents
A kind of mangosteen turmeric product and its preparation method and application Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/38—Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of mangosteen turmeric product and its preparation method and application.The product of the present invention is made of four kinds of mangosteen powder, curcuma powder, dandelion powder, sealwort powder compositions, these four compositions carry out scientific matching according to the principle of monarch, and piece can be pressed into after being fully mixed.The mangosteen turmeric product of the present invention is carried out the proportioning of science by monarch principle, has the function that significantly to alleviate body part pain or overall pain, which is food, can be long-term use of, without toxic side effect.
Description
Technical field
The invention belongs to field of food, is related to a kind of mangosteen turmeric product and its preparation method and application.
Background technology
Have that the people of Regional Pain or systemic pain is more and more, these pain gently then influence in the modern life in body
Quality of the life, it is heavy then influence work, cause quality of labor to decline.At present, the product almost all for treating pain on the market is medicine
Thing, has plenty of oral medicine, has plenty of externally applied drug, can be relieved pain without the food of a food font size.
Oral medicine side effect is larger, and seriously injure one's stomach intestines, have impact on the use of oral analgesic；Externally applied drug, due to the use of rising
Due to come inconvenient, also influencing its use for lenitive.Therefore, existing market is to no toxic side effect, and conveniently
The food of edible food font size generates strong demand.
Patent CN201510245020 discloses kidney tonifying, essence replenishing, disperse blood stasis and dredge collateral, the Chinese medicine of soft arteries and veins ecchymose removing.The kidney tonifying of the invention
Replenishing essence, disperse blood stasis and dredge collateral, the Chinese medicine of soft arteries and veins ecchymose removing are by Herba Epimedii, ground bettle, ganoderma lucidum, Radix Salviae Miltiorrhizae, turmeric, hawthorn, dandelion, mulberry leaf group
Into specifically for carotid atherosclerosis companion's patch forms kidney deficiency blood stasis, the turbid numbness type disease of phlegm is effectively treated.For treatment
The disease provides the effect of a kind of new reliable ideal medicament, by for the recovery band of numerous middle-older patients for suffering from above-mentioned illness
To wish, but the Chinese medicine does not have the effect for alleviating body part pain or overall pain, and is Chinese medicine, it is impossible to long-term clothes
With.
Patent CN201610706203 discloses double yellow blood-enrich highland barley rice cakes of a kind of Schisandra chinensis and preparation method thereof, by
The raw material composition of following parts by weight：Highland barley 130-140, glutinous rice 60-65, sucrose 5-6, brewex's grains 3-5, Hericium erinaceus 4-7, mangosteen 8-
10th, balsam pear 5-7, Ovum Anas domestica yolk freeze-dried powder 2-4, Chinese chestnut 6-9, sealwort 2-4, Radix Codonopsis 3-5, Schisandra chinensis 4-6, radix astragali 2-4, sucrose fat
Acid esters 0.6-0.8, appropriate amylase, appropriate Pullulanase.Invention brewex's grains, the Hericium erinaceus etc. are not only rich in nutrient, also
Schisandra chinensis, sealwort with addition etc. have effects that blood-enrich highland barley rice cake.But body part is not alleviated in the invention
The effect of pain or overall pain.
The content of the invention
For overcome the deficiencies in the prior art, the present invention provides a kind of mangosteen turmeric product and its preparation method and application,
Mangosteen turmeric product includes mangosteen powder, curcuma powder, dandelion powder, sealwort powder, and the proportioning of science, tool are carried out by monarch principle
Play the role of significantly alleviating body part pain or overall pain, which is food, can be long-term use of, without poison is secondary is made
With.
The present invention provides following technical solution：
A kind of mangosteen turmeric product, is made of plurality of raw materials, and the raw material includes the following each component of parts by weight：Mangosteen powder
2-6 parts, 0.5-5 parts of curcuma powder, 0.5-3 parts of dandelion powder, 0.5-3 parts of sealwort powder.
Preferably, the raw material includes the following each component of parts by weight：3-5 parts of mangosteen powder, 1-3 parts of curcuma powder, Pu Gong
0.6-2 parts of English powder, 0.6-2 parts of sealwort powder.
Any of the above-described scheme is preferably, and the raw material includes the following each component of parts by weight：3.5 parts of mangosteen powder, turmeric
2.5 parts of powder, 1.5 parts of dandelion powder, 1.5 parts of sealwort powder.
Any of the above-described scheme is preferably, and the raw material includes the following each component of parts by weight：4 parts of mangosteen powder, curcuma powder 2
Part, 1 part of dandelion powder, 1 part of sealwort powder.
Any of the above-described scheme is preferably, and the mangosteen turmeric product is powder, pulvis, tablet, granule, decoction, mouth
Take any one in liquid, lotion and beverage.
The present invention also provides the preparation method of above-mentioned mangosteen turmeric product, the mangosteen turmeric product is tablet, preparation side
Method includes following steps：
(1) by the mangosteen powder, curcuma powder, dandelion powder, sealwort powder, by matching 50-100 mesh sieves, own after sieving
Raw material is weighed；
(2) the load weighted raw material of step (1) is mixed, incorporation time is 10-20 minutes；
(3) material for mixing step (2) carries out tabletting；
(4) the good mangosteen turmeric piece of step (3) tabletting is packed, bottle neck aluminium foil sealing, vanning；
(5) after packing, the qualified storage of product laboratory detection.
Any of the above-described scheme is preferably, and the mangosteen powder, curcuma powder, dandelion powder, sealwort powder cross 80 mesh sieves.
Any of the above-described scheme is preferably, and in step (2), incorporation time is 15 minutes.
Any of the above-described scheme is preferably, and in step (2), mixing uses CH-200 mixers.
Any of the above-described scheme is preferably, and in step (3), the material that step (2) is mixed carries out tabletting, tableting pressure
For thousand Ns of 4-5, loading 6-6.8mm, every 1 gram of net content.
Any of the above-described scheme is preferably, and in step (3), the material that step (2) is mixed carries out tabletting, tableting pressure
For 4.8 thousand Ns, loading 5.9mm, every 1 gram of net content, checks a net content in every 10 minutes, it is desirable to which net content reaches
1.02-1.05 between gram.
Any of the above-described scheme is preferably, in step (3), using tabletting machine, the model ZPW-19B of tablet press machine.
Any of the above-described scheme is preferably, and in step (4), the good mangosteen turmeric piece of tabletting is packed, per bottled 60
Gram, every bottle puts one bag of 2 grams of drier, bottle neck aluminium foil sealing, and the mangosteen turmeric piece sealed is labelled, cased.
The above-mentioned mangosteen turmeric product of the present invention is used to prepare food.
The above-mentioned mangosteen turmeric product of the present invention is used to prepare beverage.
The above-mentioned mangosteen turmeric product of the present invention is used to prepare the medicine for the treatment of pain.
In inventive formulation the effect of mangosteen：Mangosteen is mild-natured, sweet in flavor, slightly sour.Mangosteen skin：It is cool in nature, bitter, puckery, invigorating the spleen life
Tianjin, antidiarrheal.Mangosteen skin：Anti-inflammatory analgetic, cures mainly insufficiency of the spleen diarrhoea, and dry, burns, and scald, eczema, stomatitis, mangosteen contains abundant
Protein and lipid, have to body and take a tonic or nourishing food to build up one's health effect well, to it is weak, malnutritive, there is good maintenance to act on after being ill.
The mangosteen flavones contained in mangosteen has anti-inflammatory, chemically-resistant anoxia functions, analgesia, hypoglycemic effect；Mangosteen is dry, refrigerant with dropping
Antipyretic effect；Mangosteen contains abundant protein and lipid, has to body and takes a tonic or nourishing food to build up one's health effect well；Rich in vitamin and mineral
Matter, beauty skin.
The effect of turmeric：Turmeric is pungent, bitter, and temperature, returns spleen, Liver Channel, turmeric energy promoting the circulation of qi broken stasis of blood is inducing meastruation to relieve menalgia；Effect for reducing blood fat；
Antitumor action；Anti-inflammatory effect；The generation and secretion of bile can be increased, and gallbladder contraction can be promoted；Antioxidation.Turmeric is also
For chest side of body shouting pain, amenorrhoea, abdominal mass, rheumatism shoulder arm pain, tumbling and swelling.
The effect of dandelion：Resisting pathogenic microbes；Liver protection, cholagogic；Anti-gastric-ulcer；Strengthen body's immunity.Also have
It is clearing heat and detoxicating, the effect of dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia.For furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharyngalgia, lung carbuncle, acute appendicitis,
Jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.Control acute mastitis, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctivitis, cold, fever, urgency
Property tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections, worm snake bite.
The effect of sealwort：Siberian solomonseal rhizome polysaccharide strengthens the immune of humoral immune function and cell, has the function of anti-inflammatory analgetic；
With obvious hypoglycemic, effect for reducing blood fat；Increase coronary flow, significantly improve hypoxia-bearing capability.Cure mainly：Deficiency of yin and overstrain cough；
Xeropulmonary cough；It is insufficiency of the spleen weak；Few dry of food；Quench one's thirst；Deficiency of the kidney soreness and weakness of waist and knees；Impotence and seminal emission；Tinnitus mesh is dark；Poliosis；It is physically weak
Win thin；Wind favus disease.
The product of the present invention is made of four kinds of mangosteen powder, curcuma powder, dandelion powder, sealwort powder compositions, these four compositions
Scientific matching is carried out according to the principle of monarch, piece can be pressed into after being fully mixed.The present invention provides a kind of mangosteen turmeric system
Product and its preparation method and application, mangosteen turmeric product includes mangosteen powder, curcuma powder, dandelion powder, sealwort powder, by monarch
Principle carries out the proportioning of science, has the function that significantly to alleviate body part pain or overall pain, which is food, can
With long-term use, without toxic side effect.
Embodiment
In order to further appreciate that the technical characteristic of the present invention, the present invention is explained in detail with reference to specific embodiment
State.Embodiment only to the present invention have the function that it is exemplary, without the effect of any restrictions, those skilled in the art
The modification for any unsubstantiality made on the basis of the present invention, should all belong to protection scope of the present invention.
Mangosteen powder, curcuma powder, dandelion powder, the sealwort powder of the present invention is purchased from the gloomy limited public affairs of not natural product in Shaanxi
Department.
Embodiment 1：
A kind of mangosteen turmeric product, is made of plurality of raw materials, and the raw material includes the following each component of parts by weight：Mangosteen powder
3 parts, 1 part of curcuma powder, 1 part of dandelion powder, 1 part of sealwort powder.
In the present embodiment, the mangosteen turmeric product is tablet.
The preparation method of mangosteen turmeric product described in the present embodiment, the mangosteen turmeric product is tablet, including following
Each step：
(1) qualified raw material mangosteen powder, curcuma powder, dandelion powder, sealwort powder is examined to match somebody with somebody by technology preparation the said goods
Than batch plant sieve 80 mesh, all materials electronic scale between weighing is weighed after sieving；
(2) weighing workshop material pass-through box has been weighed and has been delivered to groove profile compound department, material is launched to CH-200 and is mixed
In conjunction machine, material is released with stainless steel barrel within 15 minutes by technological requirement setting incorporation time；
(3) material pass-through box will be mixed and be delivered to the progress tabletting of tabletting workshop, tablet press machine model ZPW-19B, tablet press machine
Pressure is 4.8 thousand Ns, loading 5.9mm, every 1 gram of net content, checks a net content within every 10 minutes, it is desirable to which net content reaches
1.02-1.05 between gram；
(4) the good mangosteen turmeric piece pass-through box of tabletting is packed between interior hired car, per bottled 60 grams, every bottle puts one bag
2 grams of drier, bottle neck aluminium foil sealing, the mangosteen turmeric piece sealed are delivered to outer packing workshop and are labelled, cased；
(5) the mangosteen turmeric piece bottle that interior bag transmits is labelled, the label coding date of manufacture, posts label mangosteen turmeric
Piece loads big case, per 120 bottles of box installed；
(6) the qualified storage of product laboratory detection.
Embodiment 2：
A kind of mangosteen turmeric product, is made of plurality of raw materials, and the raw material includes the following each component of parts by weight：Mangosteen powder
2 parts, 2 parts of curcuma powder, 2 parts of dandelion powder, 1.5 parts of sealwort powder.
In the present embodiment, the mangosteen turmeric product is tablet.
The preparation method of mangosteen turmeric product described in the present embodiment, the mangosteen turmeric product is tablet, including following
Each step：
(1) qualified raw material mangosteen powder, curcuma powder, dandelion powder, sealwort powder is examined to match somebody with somebody by technology preparation the said goods
Than batch plant sieve 80 mesh, all materials electronic scale between weighing is weighed after sieving；
(2) weighing workshop material pass-through box has been weighed and has been delivered to groove profile compound department, material is launched to CH-200 and is mixed
In conjunction machine, material is released with stainless steel barrel within 15 minutes by technological requirement setting incorporation time；
(3) material pass-through box will be mixed and be delivered to the progress tabletting of tabletting workshop, tablet press machine model ZPW-19B, tablet press machine
Pressure is 4.8 thousand Ns, loading 5.9mm, every 1 gram of net content, checks a net content within every 10 minutes, it is desirable to which net content reaches
1.02-1.05 between gram；
(4) the good mangosteen turmeric piece pass-through box of tabletting is packed between interior hired car, per bottled 60 grams, every bottle puts one bag
2 grams of drier, bottle neck aluminium foil sealing, the mangosteen turmeric piece sealed are delivered to outer packing workshop and are labelled, cased；
(5) the mangosteen turmeric piece bottle that interior bag transmits is labelled, the label coding date of manufacture, posts label mangosteen turmeric
Piece loads big case, per 120 bottles of box installed；
(6) the qualified storage of product laboratory detection.
Embodiment 3：
A kind of mangosteen turmeric product, is made of plurality of raw materials, and the raw material includes the following each component of parts by weight：Mangosteen powder
5 parts, 3 parts of curcuma powder, 2 parts of dandelion powder, 2 parts of sealwort powder.
In the present embodiment, the mangosteen turmeric product is tablet.
The preparation method of mangosteen turmeric product described in the present embodiment, the mangosteen turmeric product is tablet, including following
Each step：
(1) qualified raw material mangosteen powder, curcuma powder, dandelion powder, sealwort powder is examined to match somebody with somebody by technology preparation the said goods
Than batch plant sieve 80 mesh, all materials electronic scale between weighing is weighed after sieving；
(2) weighing workshop material pass-through box has been weighed and has been delivered to groove profile compound department, material is launched to CH-200 and is mixed
In conjunction machine, material is released with stainless steel barrel within 15 minutes by technological requirement setting incorporation time；
(3) material pass-through box will be mixed and be delivered to the progress tabletting of tabletting workshop, tablet press machine model ZPW-19B, tablet press machine
Pressure is 4.8 thousand Ns, loading 5.9mm, every 1 gram of net content, checks a net content within every 10 minutes, it is desirable to which net content reaches
1.02-1.05 between gram；
(4) the good mangosteen turmeric piece pass-through box of tabletting is packed between interior hired car, per bottled 60 grams, every bottle puts one bag
2 grams of drier, bottle neck aluminium foil sealing, the mangosteen turmeric piece sealed are delivered to outer packing workshop and are labelled, cased；
(5) the mangosteen turmeric piece bottle that interior bag transmits is labelled, the label coding date of manufacture, posts label mangosteen turmeric
Piece loads big case, per 120 bottles of box installed；
(6) the qualified storage of product laboratory detection.
Embodiment 4：
A kind of mangosteen turmeric product, is made of plurality of raw materials, and the raw material includes the following each component of parts by weight：Mangosteen powder
3.5 parts, 2.5 parts of curcuma powder, 1.5 parts of dandelion powder, 1.5 parts of sealwort powder.
In the present embodiment, the mangosteen turmeric product is tablet.
The preparation method of mangosteen turmeric product described in the present embodiment, the mangosteen turmeric product is tablet, including following
Each step：
(1) qualified raw material mangosteen powder, curcuma powder, dandelion powder, sealwort powder is examined to match somebody with somebody by technology preparation the said goods
Than batch plant sieve 80 mesh, all materials electronic scale between weighing is weighed after sieving；
(2) weighing workshop material pass-through box has been weighed and has been delivered to groove profile compound department, material is launched to CH-200 and is mixed
In conjunction machine, material is released with stainless steel barrel within 15 minutes by technological requirement setting incorporation time；
(3) material pass-through box will be mixed and be delivered to the progress tabletting of tabletting workshop, tablet press machine model ZPW-19B, tablet press machine
Pressure is 4.8 thousand Ns, loading 5.9mm, every 1 gram of net content, checks a net content within every 10 minutes, it is desirable to which net content reaches
1.02-1.05 between gram；
(4) the good mangosteen turmeric piece pass-through box of tabletting is packed between interior hired car, per bottled 60 grams, every bottle puts one bag
2 grams of drier, bottle neck aluminium foil sealing, the mangosteen turmeric piece sealed are delivered to outer packing workshop and are labelled, cased；
(5) the mangosteen turmeric piece bottle that interior bag transmits is labelled, the label coding date of manufacture, posts label mangosteen turmeric
Piece loads big case, per 120 bottles of box installed；
(6) the qualified storage of product laboratory detection.
Embodiment 5：
A kind of mangosteen turmeric product, is made of plurality of raw materials, and the raw material includes the following each component of parts by weight：Mangosteen powder
4 parts, 2 parts of curcuma powder, 1 part of dandelion powder, 1 part of sealwort powder.
In the present embodiment, the mangosteen turmeric product is tablet.
The preparation method of mangosteen turmeric product described in the present embodiment, the mangosteen turmeric product is tablet, including following
Each step：
(1) qualified raw material mangosteen powder, curcuma powder, dandelion powder, sealwort powder is examined to match somebody with somebody by technology preparation the said goods
Than batch plant sieve 80 mesh, all materials electronic scale between weighing is weighed after sieving；
(2) weighing workshop material pass-through box has been weighed and has been delivered to groove profile compound department, material is launched to CH-200 and is mixed
In conjunction machine, material is released with stainless steel barrel within 15 minutes by technological requirement setting incorporation time；
(3) material pass-through box will be mixed and be delivered to the progress tabletting of tabletting workshop, tablet press machine model ZPW-19B, tablet press machine
Pressure is 4.8 thousand Ns, loading 5.9mm, every 1 gram of net content, checks a net content within every 10 minutes, it is desirable to which net content reaches
1.02-1.05 between gram；
(4) the good mangosteen turmeric piece pass-through box of tabletting is packed between interior hired car, per bottled 60 grams, every bottle puts one bag
2 grams of drier, bottle neck aluminium foil sealing, the mangosteen turmeric piece sealed are delivered to outer packing workshop and are labelled, cased；
(5) the mangosteen turmeric piece bottle that interior bag transmits is labelled, the label coding date of manufacture, posts label mangosteen turmeric
Piece loads big case, per 120 bottles of box installed；
(6) the qualified storage of product laboratory detection.
Embodiment 6：
The present embodiment and the difference of embodiment 1 are：The difference of preparation method.
The preparation method of mangosteen turmeric product described in the present embodiment, the mangosteen turmeric product is tablet, including following
Each step：
(1) qualified raw material mangosteen powder, curcuma powder, dandelion powder, sealwort powder is examined to match somebody with somebody by technology preparation the said goods
Than batch plant sieve 100 mesh, all materials electronic scale between weighing is weighed after sieving；
(2) weighing workshop material pass-through box has been weighed and has been delivered to groove profile compound department, material is launched to CH-200 and is mixed
In conjunction machine, material is released with stainless steel barrel within 15 minutes by technological requirement setting incorporation time；
(3) material pass-through box will be mixed and be delivered to the progress tabletting of tabletting workshop, tablet press machine model ZPW-19B, tablet press machine
Pressure is 4.8 thousand Ns, loading 5.9mm, every 1 gram of net content, checks a net content within every 10 minutes, it is desirable to which net content reaches
1.02-1.05 between gram；
(4) the good mangosteen turmeric piece pass-through box of tabletting is packed between interior hired car, per bottled 40 grams, every bottle puts one bag
2 grams of drier, bottle neck aluminium foil sealing, the mangosteen turmeric piece sealed are delivered to outer packing workshop and are labelled, cased；
(5) the mangosteen turmeric piece bottle that interior bag transmits is labelled, the label coding date of manufacture, posts label mangosteen turmeric
Piece loads big case, per 120 bottles of box installed；
(6) the qualified storage of product laboratory detection.
Experimental example 1：
1st, test specimen：
Sample 1：Sample prepared by the embodiment of the present invention 5.
Reference substance 1：A kind of mangosteen turmeric product, the raw material include the following each component of parts by weight：3 parts of mangosteen powder, ginger
1 part of bloom, 1 part of sealwort powder.Preparation method is same as Example 5.
Reference substance 2：A kind of mangosteen turmeric product, the raw material include the following each component of parts by weight：2 parts of mangosteen powder, ginger
2 parts of bloom, 1.5 parts of sealwort powder.Preparation method is same as Example 5.
Reference substance 3：A kind of mangosteen turmeric product, the raw material include the following each component of parts by weight：3.5 parts of mangosteen powder,
2.5 parts of curcuma powder, 1.5 parts of dandelion powder.
Reference substance 4：A kind of mangosteen turmeric product, the raw material include the following each component of parts by weight：5 parts of mangosteen powder, ginger
3 parts of bloom, 2 parts of dandelion powder.Preparation method is same as Example 5.
Reference substance 5：A kind of mangosteen turmeric product, the raw material include the following each component of parts by weight：4 parts of mangosteen powder, ginger
2 parts of bloom, 0.5 part of dandelion powder, 1 part of sealwort powder.Preparation method is same as Example 5.
2nd, experimentation
Totally 120 people, age between 28-79 Sui, are randomly divided into 6 groups, every group of 20 people；With local pain or systemic pain
3 months bitterly and more than, exclude the cause of disease or mechanical damage.Record pain, symptomatic condition before patient takes.3 times a day, every time backward
4, continuous one month, take classification record pain condition behind 7 days and one month.Pain Grading quantitative criteria, refers to table 1 below.
1 Pain Grading quantitative criteria of table
3rd, experimental result is shown in Table 2.
2 pain situation of change of table records result
Table 2 the results show that compared with reference substance 1-5, the effect in terms of alleviating and improving pain of sample 1 is best, takes
Mangosteen turmeric piece prepared by embodiment 5, after a week, pain improvement rate are 85%, take the mangosteen turmeric piece of the preparation of embodiment 5,
After one month, pain improvement rate is 95%, obviously higher than reference substance 1-5.Experimental example 2：
1st, sample 1-5：Sample prepared by 1-5 of the embodiment of the present invention.
Reference substance 1：Sample prepared by patent 200310107311.X embodiments 1；
Reference substance 2：Sample prepared by 200410026331.9 embodiment 1 of patent；
Reference substance 3：Sample prepared by 201310345691.4 embodiment 1 of patent.
Reference substance 4：A kind of mangosteen turmeric product, the raw material include the following each component of parts by weight：4 parts of mangosteen powder, ginger
2 parts of bloom, 6 parts of dandelion powder, 1 part of sealwort powder.Preparation method is same as Example 5.
2nd, case scenario
Diagnostic criteria
360 volunteers are selected, the range of age is 28~79 years old.Volunteer's stochastic averagina is divided into 9 groups, every group of 40 people.
3rd, observational technique
Test group 1-5 takes the sample of 1-5 of the embodiment of the present invention daily, 3 times for each person every day, 4 (every net contents
1 gram)；Control group 1-4 takes the sample of reference substance 1-4 respectively daily, is specifically taken according to the instructions of taking in its specification
With.Continuously take 1 month, record pain situation of change.Follow 1 Pain Grading quantitative criteria of table, after taking one month, pain
It is notable to decline two-stage or more (including disappearance), and it is effective that pain, which declines level-one, and pain is unchanged to be invalid.
4th, 3 be the results are shown in Table.
Table 3, improve pain clinical test results
| Significantly | Effectively | It is invalid | Total effective rate | |
| Sample 1 | 21 | 12 | 7 | 82.5% |
| Sample 2 | 19 | 13 | 8 | 80% |
| Sample 3 | 17 | 15 | 8 | 80% |
| Sample 4 | 20 | 16 | 4 | 90% |
| Sample 5 | 38 | 1 | 1 | 95% |
| Control group 1 | 12 | 16 | 12 | 70% |
| Control group 2 | 20 | 8 | 12 | 70% |
| Control group 3 | 1 | 14 | 25 | 37.5% |
| Control group 4 | 19 | 8 | 13 | 67.5% |
From the data in table 3, it can be seen that the present invention compared with reference substance 1-5, sample 1-5 alleviate and improve pain in terms of effect
More preferably, sample 5 is particularly taken, after one month, pain improvement rate is 95%, obviously higher than control group 1-5.
Claims (16)
1. a kind of mangosteen turmeric product, is made of plurality of raw materials, it is characterised in that：For alleviating body part pain or whole body pain
Bitterly, it is made of following raw material：2-6 parts of mangosteen powder, 0.5-5 parts of curcuma powder, 0.5-3 parts of dandelion powder, sealwort powder 0.5-3
Part.
2. mangosteen turmeric product according to claim 1, it is characterised in that：It is made of following raw material：Mangosteen powder
3-5 parts, 1-3 parts of curcuma powder, 0.6-2 parts of dandelion powder, 0.6-2 parts of sealwort powder.
3. mangosteen turmeric product according to claim 1, it is characterised in that：It is made of following raw material：Mangosteen powder
3.5 parts, 2.5 parts of curcuma powder, 1.5 parts of dandelion powder, 1.5 parts of sealwort powder.
4. mangosteen turmeric product according to claim 1, it is characterised in that：It is made of following raw material：Mangosteen powder 4
Part, 2 parts of curcuma powder, 1 part of dandelion powder, 1 part of sealwort powder.
5. mangosteen turmeric product according to any one of claim 1 to 3, it is characterised in that：The mangosteen turmeric product
For any one in powder, pulvis, tablet, granule, decoction, oral liquid and beverage.
6. the preparation method of mangosteen turmeric product according to any one of claim 1 to 4, the mangosteen turmeric product are
Tablet, for alleviating body part pain or overall pain, preparation method includes following steps：
(1) by the mangosteen powder, curcuma powder, dandelion powder, sealwort powder, by matching 50-100 mesh sieves, all raw materials after sieving
Weighed；
(2) the load weighted raw material of step (1) is mixed, incorporation time is 10-20 minutes；
(3) material for mixing step (2) carries out tabletting；
(4) the good mangosteen turmeric piece of step (3) tabletting is packed, bottle neck aluminium foil sealing, vanning；
(5) after packing, the qualified storage of product laboratory detection.
7. the preparation method of mangosteen turmeric product according to claim 6, it is characterised in that：The mangosteen powder, curcuma powder,
Dandelion powder, sealwort powder cross 80 mesh sieves.
8. the preparation method of mangosteen turmeric product according to claim 6, it is characterised in that：In step (2), incorporation time
For 15 minutes.
9. the preparation method of mangosteen turmeric product according to claim 6, it is characterised in that：In step (2), mixing uses
CH-200 mixers.
10. the preparation method of mangosteen turmeric product according to claim 6, it is characterised in that：In step (3), by step
(2) material that mixes carries out tabletting, and tableting pressure is thousand Ns of 4-5, loading 6-6.8mm, every 1 gram of net content.
11. the preparation method of mangosteen turmeric product according to claim 6, it is characterised in that：In step (3), by step
(2) material mixed carries out tabletting, and tableting pressure is 4.8 thousand Ns, loading 5.9mm, every 1 gram of net content, every 10 points
Clock checks a net content, it is desirable to which net content reaches between 1.02-1.05 grams.
12. the preparation method of mangosteen turmeric product according to claim 6, it is characterised in that：In step (3), using pressure
Piece machine tabletting, the model ZPW-19B of tablet press machine.
13. the preparation method of mangosteen turmeric product according to claim 6, it is characterised in that：In step (4), by tabletting
Good mangosteen turmeric piece is packed, and per bottled 60 grams, every bottle puts one bag of 2 grams of drier, bottle neck aluminium foil sealing, the mountain sealed
Bamboo turmeric piece is labelled, vanning.
14. mangosteen turmeric product according to any one of claim 1 to 4 is used to prepare food, for alleviating body office
Portion's pain or overall pain.
15. mangosteen turmeric product according to any one of claim 1 to 4 is used to prepare beverage, for alleviating body office
Portion's pain or overall pain.
16. mangosteen turmeric product according to any one of claim 1 to 4 is used to prepare the medicine for the treatment of pain.
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| EGCG联合姜黄素对人卵巢癌细胞增殖的抑制作用;吴溧兴等;《江苏医药》;20151031;第41卷(第20期);第2367-2370页 * |
| 针药并用镇痛新议;陈秀贞;《中国中医基础医学杂志》;19980831;第4卷;第14-15页，尤其是第14页倒数第3行、第15页第4-5、11、18行 * |
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