CN107019780A - A kind of Chinese medicine composition for treating the proliferation of mammary gland - Google Patents

A kind of Chinese medicine composition for treating the proliferation of mammary gland Download PDF

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CN107019780A
CN107019780A CN201710062317.1A CN201710062317A CN107019780A CN 107019780 A CN107019780 A CN 107019780A CN 201710062317 A CN201710062317 A CN 201710062317A CN 107019780 A CN107019780 A CN 107019780A
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proliferation
mammary gland
minutes
chinese medicine
water
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王雯丽
吕灿辉
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Luoyang Xiong Yuan Yuan Medical Group Ltd By Share Ltd
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Luoyang Xiong Yuan Yuan Medical Group Ltd By Share Ltd
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The present invention relates to a kind of Chinese medicine composition for treating the proliferation of mammary gland.The technical scheme of use is:It is made up of following raw material medicaments in part by weight proportioning:Pangolin 3g 9g, selfheal 8g 15g, marine alga 20g 50g, fritillaria 9g 18g, frankincense 3g 10g, oyster 10g 20g, literary art 10g 30g, myrrh 5g 12g.By pangolin, selfheal, marine alga, fritillaria, oyster, literary art is soaked 30 minutes with water, is decocted 2 times with flat marmite, decocts use 23 times of water degree of being every time, and first time decocting time is 40 minutes, and second is 30 minutes, decoct it is good after mixing after medical filtration twice.By frankincense, the taste Chinese medicine of myrrh two is ground afterwards with decoction while taking after mixing it with water.This medicine is directed to the proliferation of mammary gland, and the symptom such as tuberculosis fibroma is evident in efficacy, and pure Chinese medicinal preparation is nontoxic without any hormone without chemical components, has no side effect, and convenient to take, it is easy to absorb, instant effect is cheap.By clinic application observation confirm, with it is quick-acting, efficient, long-acting the characteristics of, later stage follow-up recurrence rate is low.

Description

A kind of Chinese medicine composition for treating the proliferation of mammary gland
Technical field
The invention belongs to the field of Chinese medicines, it is related to a kind of Chinese medicine composition for treating the proliferation of mammary gland.
Background technology
The proliferation of mammary gland is a kind of common breast disease that women easily falls ill, wide with incidence of disease height, covering the range of age The characteristics of, the women that there are about 70%-80% is suffering from the different degrees of proliferation of mammary gland, and with the change of habits and customs, hair In the trend risen year by year, also there is this kind of illness in male in recent years in sick rate.
The proliferation of mammary gland is the hyperplasia of prostate of mammary gland interstitial mostly, and hyperplasia can be betided around glandular tube and with differing in size Tumour is formed;The nipple sample hyperplasia of epithelium is may also occur in glandular tube and shows as, with latex dust cystic dilatation.The hair of the proliferation of mammary gland Cause of disease is because it is generally acknowledged that caused by by several factors once:One is endocrinopathy, many factors such as neural, immune and micro- The unbalance of the various endocrine hormones of body can be caused;Two be mental element, and under long-term nervous anxiety state, opium can be opened Power increases, and neurotransmitter environment changes, and generation estrogen/dopamine is uncoordinated, then causes PRL secretion increases, and may Cause or aggravate cyclomastopathy;Three be to cause female hormone rise to cause the proliferation of mammary gland by hepatopathy or long-term steroid class medicine. Due to having the possibility for developing into breast cancer after the seriously ill sub-fraction of the proliferation of mammary gland, therefore the treatment sick to this is not allowed to neglect Depending on.
The traditional Chinese medical science is early on the books to the illness of the proliferation of mammary gland, is called " newborn addiction ", " newborn pestilence ", " newborn core ".The traditional Chinese medical science thinks mammary gland The cause of disease of hyperplasia mainly has following four:One is stagnation of liver qi, depressed rage impairing the liver, it is difficult to mediates, causes transporting not smooth, and moisture is difficult Row, poly- phlegm hardly possibleization, phlegm congeals into block;Two be fire excess from yin deficiency, and excessive sexual strain, eating cooks pan-fried, causes interior hyperactivity of fire to be contained, body fluid deficiency, is converged Phlegm is polymerized to, hinders and gives birth to block;Three be Chong and Ren channel disorder, disorderly through water, and qi and blood is mutually well-behaved, and knot network is blocking;Four be that phlegm-blood stasis stagnates, qi and blood water phlegm It is cementing blocking.
The content of the invention
For problem above, the present invention provides a kind of Chinese medicine composition for treating the proliferation of mammary gland, for the proliferation of mammary gland, tuberculosis The symptoms such as fibroma, by eliminating stasis and resolving masses, clearing heat-fire, the stagnant purpose for reaching elimination or reducing tubercle of promoting blood circulationization, with effect Stable, expense is low, and no pain has no toxic side effect, the conditioning whole body, the advantage of efficient long-acting.
The technical solution adopted by the present invention is:A kind of Chinese medicine composition for treating the proliferation of mammary gland, it is characterised in that following The weight of bulk drug is respectively:
A kind of described preparation method for treating the Chinese medicine composition of limb adynamia numbness and pain caused by neck waist, it is special Levy and be:
The first step:By pangolin, selfheal, marine alga, fritillaria, oyster, literary art is soaked 30 minutes with water, is decocted with flat marmite Boil 2 times, decoct every time with 2-3 times of water degree of being, first time decocting time is 40 minutes, and second is 30 minutes, decoct it is good after two Mixed after secondary medical filtration.
Second step:By frankincense, the taste Chinese medicine of myrrh two is ground afterwards with decoction while taking after mixing it with water.
Each bulk drug drug effect is as follows:
Pangolin, also known as first piece, Chuan Jia, river first piece, scale and shell piece, fervent scale etc..With the lower breast that stimulates the menstrual flow, eliminating stasis and resolving masses, disappear Carbuncle apocenosis, effect of wind-cold-dampness arthralgia.Cure mainly the symptoms such as alactation, carbuncle sore tumefacting virus, tumor mass, amenorrhoea, painful swelling of joints.Taste It is salty, cold nature.Return liver, stomach.
Selfheal, alias:Wheat head selfheal, iron wire selfheal (Yunnan book series), Mai Xia is withered, the iron wire summer is withered, sunset, Nedong Deng.With clearing heat-fire, improving eyesight, effect of mass dissipating and swelling eliminating.Cure mainly red eye, swell pain, dizziness of having a headache, mesh pearl nyctalgia, scrofula, goiter and tumor, Acute mastitis swells and ache.Pungent, hardship, it is cold in nature.Return liver, gallbladder channel.
Marine alga, alias falls head, gloiopeltis, Tan, marine alga dish, black dish, sea-tangle.With dissolving phlegm softening and resolving hard mass, inducing diuresis for removing edema Effect.Cure mainly goiter and tumor, scrofula, testiclar gall, phlegm and retained fluid oedema.It is bitter, salty, it is cold in nature.Return liver, stomach, kidney channel.
Fritillaria, alias:Diligent mother, bitter dish, bitter flower, empty grass, medicine are real.There is relieving cough and reducing sputum, heat-clearing dissipating bind.Cure mainly phlegm Hot cough and asthma, acute mastitis, scrofula subcutaneous nodule.Bitter, cold nature.Return lung, the heart channel of Hang-Shaoyin.
Frankincense, alias nipple is fragrant, day pool is fragrant.Have effects that promoting blood circulation and stopping pain, ventilationization be stagnant, detumescence and promoting granulation.Cure mainly the obstruction of qi in the chest It is pained, gastral cavity pain, dysmenorrhoea Amenorrhea, postpartum stasis, abdominal mass stomachache, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore. Pungent, hardship, it is warm-natured.The thoughts of returning home, liver, the spleen channel.
Oyster, alias oyster is yellow, oyster.With beneficial cloudy checking exuberance of yang, astringent or styptic treatment for spontaneous sweating, effect of softening and resolving hard mass is restrained.Cure mainly deficiency of Yin sun It is high caused by agitation, insomnia, dizziness headache, one's ears rang and spots danced before one's eyes, hectic fever night sweat, abnormal sweating, band under, seminal emission, tie swell, enclosed mass, convulsive seizure due to phlegm-fire scrofula Scrofula.Taste is salty, cold nature.Return liver, courage, kidney channel.
Wen Shu, alias kaempferia pundurata, fluffy medicine, zedoary, Guang Mao, fluffy art, blue or green ginger, Qiang seven, wide art, evil mind ginger.With promoting the circulation of qi Blood-breaking, effect of Xiao Ji Zhi Tong.Abdominal distnetion Tong , Disorder lumps in the abdomen are cured mainly, are gathered, place food does not disappear, and women's blood stasis, traumatic injury is made Bitterly.Pungent, hardship, it is warm-natured.Return liver, the spleen channel.
Myrrh, alias myrrh, bright myrrh.With scattered stasis pain, effect of detumescence and promoting granulation.Cure mainly chest impediment and cardialgia, pain of gastric cavity Bitterly, dysmenorrhoea Amenorrhea postpartum stasis , Disorder lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, traumatic injury, the treatment of the illness such as carbuncle swells sore.Pungent, hardship, It is mild-natured.The thoughts of returning home, liver, the spleen channel.
The treatment clinical observation of the present invention is as follows:
(1) general information
Patient 193,20-40 Sui 117,40-60 Sui 31, more than 60 years old 45.
(2) diagnostic criteria
Breast pain, lump in breast, nipple discharge.
(3) treatment method
The first step:By pangolin 6g, selfheal 10g, marine alga 30g, fritillaria 12g, oyster 15g, literary art 15g soak 30 with water Minute, decocted 2 times with flat marmite, each decoction is 40 minutes, second with 2-3 times of water degree of being, first time decocting time For 30 minutes, decoct it is good after mix twice after medical filtration.
Second step:By frankincense 9g, the taste Chinese medicines of myrrh 9g bis- are ground afterwards with decoction while taking after mixing it with water.
Twice daily, divide and take sooner or later.
(4) efficacy assessment standard
Cure:Clinical symptom disappearance.
Take a turn for the better:Pain relief, lump reduces, and discharge is not common.
It is invalid:Symptom is not improved.
(5) therapeutic effect
Clinical cure 119, accounts for 61%;Effective 67, account for 35%;Invalid 7, account for 4%;Total effective rate 96%.Cure Latter year does not recur 82, accounts for 70%.The purpose alleviated and fully recovered can be basically reached by the medication of the 1-3 course for the treatment of.
The proliferation of mammary gland is directed to the beneficial effects of the invention are as follows, this medicine, and the symptom such as tuberculosis fibroma is evident in efficacy, pure Chinese medicine system Agent, it is nontoxic without any hormone without chemical components, have no side effect, convenient to take, it is easy to absorb, instant effect is cheap. By clinic application observation confirm, with it is quick-acting, efficient, long-acting the characteristics of, later stage follow-up recurrence rate is low.
Embodiment
Embodiment 1
(1) a kind of Chinese medicine composition for treating the proliferation of mammary gland, it is characterised in that the weight of following bulk drug is respectively:
(2) preparation method
The first step:By pangolin 3g, selfheal 8g, marine alga 20g, fritillaria 9g, oyster 10g, literary art 10g soak 30 points with water Clock, is decocted 2 times with flat marmite, and each decoction is 40 minutes with 2-3 times of water degree of being, first time decocting time, is for the second time 30 minutes, decoct it is good after mix twice after medical filtration.
Second step:By frankincense 3g, the taste Chinese medicines of myrrh 5g bis- are ground afterwards with decoction while taking after mixing it with water.
Embodiment 2
(1) a kind of Chinese medicine composition for treating the proliferation of mammary gland, it is characterised in that the weight of following bulk drug is respectively:
The first step:By pangolin 6g, selfheal 12g, marine alga 30g, fritillaria 14g, oyster 15g, literary art 20g soak 30 with water Minute, decocted 2 times with flat marmite, each decoction is 40 minutes, second with 2-3 times of water degree of being, first time decocting time For 30 minutes, decoct it is good after mix twice after medical filtration.
Second step:By frankincense 6g, the taste Chinese medicines of myrrh 8g bis- are ground afterwards with decoction while taking after mixing it with water.
Exemplary embodiments
Zhao, female 43 years old comes this and gone to a doctor on March 8th, 2010, weight, patient when readme is light during bilateral swollen breasts over 3 years Self-induction has not big harm, and feels within nearly one month that pain is aggravated, and touches pain and increases, checks finding:Bilateral breast body of gland is thickened, and structure is owed Regular echo owes homogeneous.It is diagnosed as bilateral breast hyperplasia.Then go home to take by top seven patches of making up the prescription, examine within one week, state later It takes just feels to considerably reduce after 3 medications, and seven medications feel that pain disappears substantially after administration, and medicine has been suited the medicine to the illness, and enjoins it to take again Seven medications are consolidated.Follow-up has no repeatedly after 1 year.
Cui, female 40 years old, Luoyang Songxian County Mu Zhi streets village people.Come to go to a doctor within 2 23rd, 2008, private prosecution is over nearly three months, Often feel swollen, uncomfortable in chest bitter taste rib, apocleisis, paramenia, breast pain, pain is aggravated and nipple discharge over nearly three days, looks into its pair Visible borders clearly low echo nodules, size about 4 × 2mm on the outside of the side proliferation of mammary gland, left side mammary gland nipple.CDFI:Blood flow is not See obvious exception.Decoctions are pasted for state of an illness administration seven, are examined again after one week, its rib is swollen, uncomfortable in chest, anorexia greatly takes on a new look, breast Pain phenomenon is disappeared substantially, occasionally has pain but disappears quickly, and patient requests are taken seven patch medicines by original side to prevent repeatedly again.Chased after after half a year Anti- not occur repeatedly, menstruation also recovers normal.
Mr. Wang, female, Pingdingshan City Lushan County Liang Wa people from towns makees clothes business at Lushan county town, 2009 is illustrated in through friend Come here on October 18, in go to a doctor.State it and suffer from Breast Nodules for 3 years, often feel like the intermittent distending pain of both sides breast, the moon Through imbalance, doctor trained in Western medicine once advised her operative treatment, and he or she is unwilling to perform an operation.Through color ultrasound examination:
Bilateral breast is detected:Left side breast thickness 13MM, in seeing a size about 5X3MM no echo areas in the body of gland of left breast inner side, border is clear, Interior entrant sound is good, and rear echo slightly strengthens, and remaining place's mammary gland internal echo is evenly distributed, and has no obvious occupying lesion.Right mammary gland Thick 15MM, internal echo is normal, has no obvious occupying lesion.
CDFI:Interior no abnormality seen blood flow signal.
Diagnostic comments:Galactoncus.
Make up the prescription and ten paste back decoction.November 2 examined again, states the intermittent distending pain phenomenon of its both sides breast and is clearly better, wants by original side Continue medication and be subject to after treatment, then the patch of administration 15 continues clothes again.After one month, all diseases all disappear.Through color ultrasound examination such as ordinary person. Pay a return visit, do not have repeatedly after 1 year.Processing:Take symptom after 1 course for the treatment of of this medicine to be greatly improved, and enjoin it to consolidate after 15 days, 1 year Follow-up has no repeatedly.
Although above-mentioned specific embodiment and clinical data to the present invention is explained in detail, the present invention is not limited to above-mentioned Embodiment, in the knowledge that those of ordinary skill in the art possess, can also not depart from the premise of present inventive concept Lower various changes can be made, without possessing the modification of creative work or deforming still within protection scope of the present invention.

Claims (2)

1. a kind of Chinese medicine composition for treating the proliferation of mammary gland, it is characterised in that the weight of following bulk drug is respectively:
2. a kind of preparation method for the Chinese medicine composition for treating the proliferation of mammary gland as claimed in claim 1, it is characterised in that:
The first step:By pangolin, selfheal, marine alga, fritillaria, oyster, literary art is soaked 30 minutes with water, and 2 are decocted with flat marmite It is secondary, decoct every time with 2-3 times of water degree of being, first time decocting time is 40 minutes, and second is 30 minutes, decoct it is good after medicine twice Mixed after liquid filtering.
Second step:By frankincense, the taste Chinese medicine of myrrh two is ground afterwards with decoction while taking after mixing it with water.
CN201710062317.1A 2017-02-04 2017-02-04 A kind of Chinese medicine composition for treating the proliferation of mammary gland Pending CN107019780A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109172728A (en) * 2018-10-31 2019-01-11 田春生 A kind of drug for treating the proliferation of mammary gland

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1579511A (en) * 2004-05-18 2005-02-16 济南高华制药厂 Ready made traditional Chinese medicine for treating hyperplasia of mammary glans
CN104623546A (en) * 2015-02-08 2015-05-20 长沙佰顺生物科技有限公司 Pharmaceutical composition for treating proliferation of mammary gland

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1579511A (en) * 2004-05-18 2005-02-16 济南高华制药厂 Ready made traditional Chinese medicine for treating hyperplasia of mammary glans
CN104623546A (en) * 2015-02-08 2015-05-20 长沙佰顺生物科技有限公司 Pharmaceutical composition for treating proliferation of mammary gland

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张丽蓉等: "中药配合自制软坚散结贴治疗乳癖的临床研究", 《中国医疗前沿》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109172728A (en) * 2018-10-31 2019-01-11 田春生 A kind of drug for treating the proliferation of mammary gland

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