CN102824576A

CN102824576A - Traditional Chinese medicinal composition for treating psoriasis and preparation method thereof

Info

Publication number: CN102824576A
Application number: CN2011101600466A
Authority: CN
Inventors: 王海斌
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-06-15
Filing date: 2011-06-15
Publication date: 2012-12-19
Anticipated expiration: 2031-06-15
Also published as: CN102824576B

Abstract

The invention relates to a traditional Chinese medicinal composition for treating psoriasis and a preparation method thereof. The composition comprises the following drug materials of: by weight, 20-30 parts of Smilax glabra, 15-20 parts of root of large-flowered skullcap, 20-25 parts of Asarum Herb, 15-20 parts of coptis, 10-15 parts of rheum officinale, 5-10 parts of star anise, 20-25 parts of Polyporus umbellatus and 15-20 parts of licorice. According to the preparation method, the above drug materials are weighed; each ingredient is crushed into a powder of 80-120 meshes; then the powders are uniformly mixed and are made into capsules, pills or powders according to a conventional method. The traditional Chinese medicinal composition provided by the invention has effects of adjusting human balance, eliminating siltation, removing blood stasis, expelling wind and dissipating cold, stopping endogenous wind, alleviating convulsion, relaxing vein and relieving pain, and has advantages of short treatment course and definite therapeutic effects. Cure rate of the composition for common psoriasis reaches up to 85.3%, and its total effective rate reaches 100%.

Description

Treat psoriasic Chinese medicine composition and preparation method thereof

Technical field

The invention belongs to the field of Chinese medicines, be specifically related to psoriasic Chinese medicine composition of a kind of treatment and preparation method thereof.

Background technology

" psoriasis " belongs to commonly encountered diseases, frequently-occurring disease, and the distribution position is different, and state of an illness weight difference is very big, and psoriasic type generally can be divided into multiple; Modal is the homeliness type psoriasis, shows as erythra and generally occurs in scalp, trunk and extremity, occurs red pimple on the skin; Expansion is fused into patch or speckle gradually, and there are thicker silvery white phosphorus bits, out-of-shape in the surface; The skin lesion that has is more, is starlike over the sky, and the squama pull-up falls behind; Wipe scurf gently off and can see the red film of one deck, strike off red film and can see little petechia, medically make the sieve shape hemorrhage again.Other psoriasis type is just like pustule type psoriasis, psoriasis arthropathica, erythrodermic psoriasis etc., and these also happen occasionally, but are not too common.

It is multiple that psoriasic pathogenic factor mainly contains heredity, immunologic function disorder, direct stimulation, trauma infection contamination etc. at present, but still do not have clearly final conclusion so far.Many clinically with cell toxicant kind anti-cancer drugs such as aminopterin, ethyliminum, bimolane, cyclophosphamide, and hormone medicine treatments such as dexamethasone, prednisone, betamethasone and import injection, triamcinolone.The various preparations of above medicine and preparation thereof, though with after short run effect is arranged, control the back and be prone to recurrence, often be difficult to thorough healing.How to let the psoriatic break away from the puzzlement of the serious illness, make the thorough rehabilitation of patient, be the problem that medical circle is paid close attention to always.

Summary of the invention

The object of the present invention is to provide the psoriasic Chinese medicine composition of a kind of treatment, utilize said composition treatment psoriasis short treating period, determined curative effect is difficult for recurrence with the back.

The technical scheme that the present invention takes: the psoriasic Chinese medicine composition of a kind of treatment, form by each crude drug of following weight parts: Rhizoma Smilacis Glabrae 20-30 part, Radix Scutellariae 15-20 part; Herba Asari 20-25 part, Rhizoma Coptidis 15-20 part, Radix Et Rhizoma Rhei 10-15 part; Anistree 5-10 part, Polyporus 20-25 part, Radix Glycyrrhizae 15-20 part.

In the said Chinese medicine composition, Rhizoma Smilacis Glabrae 24 grams, Radix Scutellariae 18 grams, Herba Asari 20 grams, Rhizoma Coptidis 18 grams, Radix Et Rhizoma Rhei 12 grams, anistree 6 grams, Polyporus 21 grams, Radix Glycyrrhizae 18 grams.

The method for preparing of said Chinese medicine composition takes by weighing each crude drug, and each component is ground into 80～120 purpose powder, and mix homogeneously is processed capsule, pill or powder by conventional method then.

Pharmacology analysis:The present invention be the inventor according to oneself clinical experience for many years, get in conjunction with motherland's Chinese medicine marrow dialectical prescription, because psoriasis is damp and hot attacking due to the skin; The present invention is a purpose with heat-clearing and toxic substances removing, the cold expelling that induces sweat, expelling wind and removing dampness, reducing swelling and alleviating pain, and the adjustment total balance of the body is eliminated alluvial; Improve total balance of the body, improve skin functional recovery ability, utilize the mutual synergism between the medicine; Control psoriasic expansion and spread, reach the effect of treating both the principal and secondary aspects of a disease, reach the purpose of radical cure at last.

In the crude drug, Rhizoma Smilacis Glabrae: the property slightly sweet flavor is flat; Return liver, stomach warp, detoxifcation, dehumidifying, sharp joint; Control syphilis, stranguria with turbid discharge, muscles and bones spasm and pain, beriberi, furuncle, carbuncle, scrofula.Radix Scutellariae: nature and flavor are bitter, and are cold, return lung, gallbladder, spleen, large intestine, small intestine meridian; Cure mainly heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive; Be used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, the hyperpyrexia excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.Herba Asari: nature and flavor are hot, warm; Return lung, kidney channel, cure mainly and dispel the wind, cold expelling, row water is had one's ideas straightened out; Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.Rhizoma Coptidis: nature and flavor are bitter, cold; GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel; Heat clearing and damp drying, eliminating fire and detoxication; Be used for cold and heat and tie mutually, damp and hot middle resistance, feeling of fullness vomiting.Radix Et Rhizoma Rhei: nature and flavor are bitter, cold; Return spleen, stomach, large intestine, liver, pericardium channel; Cure mainly purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation; Be used for the excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Anistree: nature and flavor are hot, and are sweet, temperature; Be included into spleen, kidney channel; Warming YANG, cold expelling is regulated the flow of vital energy, antibacterial; Control the invasion by pathogenic cold vomiting, colic of cold type stomachache, lumbago due to renal deficiency, dried, beriberi caused by pathogenic damp.Polyporus: the property slightly sweet flavor is flat; Return spleen, kidney, urinary bladder channel; Dysuria is controlled in the diuresis eliminating dampness by diuresis, the edema distension, and beriberi is had loose bowels, pouring, turbid, leukorrhagia.Radix Glycyrrhizae: nature and flavor are sweet, and are flat; Be included into spleen, stomach, lung meridian; With middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.

Method for using: Chinese medicine composition of the present invention is processed capsule, and 3 times on the one, each 2,2 months is a course of treatment, and every capsules contains effective composition 0.3g, and other dosage forms can be with reference to this dose.

Positive beneficial effect of the present invention:

(1) Chinese medicine composition of the present invention is on the basis of secret prescription handed down in the family from generation to generation, and inheriting tradition medical science elite is in conjunction with Chinese medicine characteristics and pathogeny; Screen through research for many years, have an adjustment total balance of the body, eliminate alluvial; The effect of removing blood stasis eliminating stagnation, expelling wind and cold, relieving spasm by subduing liver-wind, removing obstruction in the collateral to relieve pain; Curing psoriasis is had the advantage of short treating period, determined curative effect, and up to 85.3%, total effective rate reaches 100% to common psoriasic cure rate.

(2) curative effect of medication of the present invention is lasting, and short treating period, instant effect are cured the back and be difficult for recurrence, has changed in the past that medicine is difficult to effect a radical cure this sick difficult problem, and method for making is simple, is worth applying clinically.

(3) drug use safety of the present invention, without any side effects, cost is low, and is easy to use, and the patient spends few, has significantly reduced patient's financial burden.

The curative effect statistics:In recent years among the 278 routine patients of treatment, wherein male 158 examples, women 120 examples, age distribution is at 20 ~ 75 years old, and between the course of disease 1 year-15 years, the overwhelming majority is the homeliness type psoriasis, accounts for 246 examples.Among the 278 routine patients, the case of fully recovering through treatment is 237 examples, accounts for 85.3%; The produce effects case is 19 examples, accounts for 6.8%, and the improvement case is 22 examples, accounts for 7.9%, total effective rate 100%.

Efficacy assessment standard:

Recovery from illness: skin lesion symptoms such as red pimple and speckle, squamous silver bits, shinny thin film, petechial hemorrhage, pustule all disappear, the arthropathy of getting involved, pain disappearance, activity freely, other conscious Signs all disappears.

Produce effects: skin lesion symptoms such as red pimple, squamous silver bits, shinny thin film, petechial hemorrhage, pustule etc. obviously disappear more than 70%, and the arthropathy of getting involved returns to normally basically, and pain obviously alleviates, and mobility significantly strengthens, and other conscious Signs obviously disappears.

Take a turn for the better: skin lesion resolution of symptoms such as red pimple, silver bits, shinny thin film, petechial hemorrhage, pustule are more than 50%, and the arthropathy of getting involved, pain alleviate to some extent, can do the activity of bending and stretching by a small margin, and other conscious Signs alleviates to some extent.

Invalid: skin lesion symptoms such as red pimple, silver bits, shinny thin film, petechial hemorrhage, pustule do not have and obviously disappear, the arthropathy of getting involved, pain no change, and activity is still limited, other conscious Signs no change.

Model case:

Case 1: Lee so-and-so, man, 55 years old.Examine in April, 2005, readme before 4 years extremity, trunk play tinea, the surface has silvery white phosphorus bits to come off, out-of-shape, the red pruritus of color, striking off red film has little petechia.Be diagnosed as the homeliness type psoriasis.Take the capsule of embodiment 1, treat after 3 months, the silvery white phosphorus bits of whole body disappear, pruritus no longer, and skin smooth, recovery from illness, recurrence is followed up a case by regular visits to so far in after treatment 1 month again subsequently.

Case 2: Zhu, man, 65 years old.Examine in JIUYUE, 2006, and readme got psoriasis 8 years, begins oneself and pay no attention to, and occurs red pimple on the extremity skin; There are thicker silvery white phosphorus bits on the surface, out-of-shape, and skin lesion is more, is starlike over the sky; Squama pull-up backwardness can be seen the red film of one deck, strikes off red diaphragm screen shape petechia, but psoriasis has the sign that increases the weight of recently, and pruritus is unusual; Myasthenia of limbs helplessly, is turned to any doctor one can find when critically ill, and has the attitude of trying in arms and comes the inventor to locate to seek to hope.Be diagnosed as the homeliness type psoriasis.Take the capsule of embodiment 2, after treatment February, pruritus alleviates, and white phosphorus bits reduce, and continue medication two months, and white phosphorus bits disappear, skin smooth, and recovery from illness, recurrence is followed up a case by regular visits to so far in after treatment 1 month again subsequently.

Case 3: Xue, woman, 70 years old.Examine in July, 2009, and originally readme had only scalp and elbow joint position proriasiform skin lesion to occur before 7 years; Since nearest 1 year, the symptom of pain appears in elbow joint, once the multi-treatment poor effect; The arthralgia phenomenon gradually is serious, joint stuffiness, myasthenia of limbs; Helplessly, having the attitude of trying in arms comes the inventor to locate to seek to hope.After diagnosing, be diagnosed as " arthrosis type psoriasis ", take the capsule of embodiment 3, after 30 days, the skin lesion symptom comes off gradually, and arthralgia makes moderate progress, and can do some flexors by a small margin; Continued medication again 30 days, the skin lesion position returns to the normal colour of skin basically fully, and the arthralgia symptom disappears, and activity freely, and is back with consolidating medication 30 days, follows up a case by regular visits to and do not see recurrence so far.

Case 4: Zhang, woman, 38 years old.In February, 2010, the readme skin lesion is just sent out on the basis of acute inflammation erythema, the shallow pustule of most intensive syringe needles to foxtail millet grain size aseptic table occurs, with a small amount of thin thin squama, after scurf comes off, has abscess to occur; Closely over the past half year, pustule increases rapidly, is fused into large stretch of pus pasty state each other, with hyperpyrexia, arthralgia and general malaise; Be diagnosed as " pustule type psoriasis ", the capsule of taking embodiment 4 is after 2 months, and pustule begins incrustation; Most of squama comes off, and continues medication 2 months, and incrustation speckle and squama disappear; Skin recovers normal color, and the back is followed up a case by regular visits to and do not seen recurrence so far with consolidating medication 30 days.

The specific embodiment

Following examples are detailed description of the invention, are not to any restriction of the present invention.

Example 1: the psoriasic Chinese medicine composition of a kind of treatment, be made up of each crude drug of following weight parts: wherein Rhizoma Smilacis Glabrae 24 restrains, Radix Scutellariae 18 grams, Herba Asari 20 grams, Rhizoma Coptidis 18 grams, Radix Et Rhizoma Rhei 12 grams, anise 6 grams, Polyporus 21 grams, Radix Glycyrrhizae 18 grams.

Method for preparing: take by weighing each crude drug, each component is ground into 80～120 purpose powder, mix homogeneously is processed capsule by conventional method then, and every contains effective composition 0.3 gram.

Example 2: basic identical with example 1, difference is:

Crude drug is formed: 20 parts of Rhizoma Smilacis Glabraes, 15 parts of Radix Scutellariaes, 20 parts of Herba Asaris, 15 parts of Rhizoma Coptidis, 10 parts of Radix Et Rhizoma Rhei, anistree 5 parts, 20 parts of Polyporus, 15 parts in Radix Glycyrrhizae.

Example 3: basic identical with example 1, difference is:

Crude drug is formed: 30 parts of Rhizoma Smilacis Glabraes, 20 parts of Radix Scutellariaes, 25 parts of Herba Asaris, 20 parts of Rhizoma Coptidis, 15 parts of Radix Et Rhizoma Rhei, anistree 10 parts, 25 parts of Polyporus, 20 parts in Radix Glycyrrhizae.

Example 4: basic identical with example 1, difference is:

Crude drug is formed: 25 parts of Rhizoma Smilacis Glabraes, 18 parts of Radix Scutellariaes, 22 parts of Herba Asaris, 16 parts of Rhizoma Coptidis, 12 parts of Radix Et Rhizoma Rhei, anistree 8 parts, 22 parts of Polyporus, 18 parts in Radix Glycyrrhizae.

Example 5: basic identical with example 1, difference is:

Crude drug is formed: 28 parts of Rhizoma Smilacis Glabraes, 17 parts of Radix Scutellariaes, 22 parts of Herba Asaris, 18 parts of Rhizoma Coptidis, 12 parts of Radix Et Rhizoma Rhei, anistree 6 parts, 21 parts of Polyporus, 17 parts in Radix Glycyrrhizae.

Claims

1. treat psoriasic Chinese medicine composition for one kind, it is characterized in that: each crude drug by following weight parts is formed: Rhizoma Smilacis Glabrae 20-30 part, Radix Scutellariae 15-20 part; Herba Asari 20-25 part, Rhizoma Coptidis 15-20 part, Radix Et Rhizoma Rhei 10-15 part; Anistree 5-10 part, Polyporus 20-25 part, Radix Glycyrrhizae 15-20 part.

2. the described Chinese medicine composition of claim 1 is characterized in that: Rhizoma Smilacis Glabrae 24 grams wherein, Radix Scutellariae 18 grams, Herba Asari 20 grams, Rhizoma Coptidis 18 grams, Radix Et Rhizoma Rhei 12 grams, anistree 6 grams, Polyporus 21 grams, Radix Glycyrrhizae 18 grams.

3. the method for preparing of the said Chinese medicine composition of claim 1, it is characterized in that: take by weighing each crude drug, each component is ground into 80～120 purpose powder, mix homogeneously is processed capsule, pill or powder by conventional method then.