CN102302651A

CN102302651A - External application Chinese medicine for treating proliferation of mammary gland

Info

Publication number: CN102302651A
Application number: CN201110242343A
Authority: CN
Inventors: 张方山
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-08-23
Filing date: 2011-08-23
Publication date: 2012-01-04

Abstract

The invention relates ton an external application Chinese medicine for treating proliferation of mammary gland, and belongs to the field of Chinese medicines. The external application Chinese medicine is characterized by being prepared from pangolin scales, paris root, white mustard seed, amber, divaricate saposhnikovia root and liquoric root in a weight ratio. According to a method of external treatment for internal diseases in traditional Chinese medical science, the external application Chinese medicine has the effects of clearing heat and detoxicating, relieving swelling and eliminating stasis and dredging collaterals and relieving pain from the outside to the inside and can be used for treating proliferation of mammary gland effectively, and the cure rate is over 90 percent; and by external application, the external application Chinese medicine is quick in effectiveness and does not have pain.

Description

The Traditional Chinese Medicine for external application of treatment cyclomastopathy

Technical field

The invention belongs to the field of Chinese medicines, particularly a kind of pure Chinese medicinal preparation of external application for curing hyperplasia of mammary glands.

Background technology

Hyperplasia of mammary glands is mastalgia, adenosis of breast and cystic hyperplasia of breast, is referred to as mammary dysplasia, for three differences of pathological changes are sent out developmental stage.Initial stage is connective tissue edema, periodicity lobular development of breast and slight hypertrophy, is mastalgia; Later stage is because repetitious stimulation, causes cyclomastopathy and returns to the past unusually, and long-term accumulation and the change on the tissue morphology takes place is irreversibility, is adenosis of breast.Wherein some can with trimester of pregnancy or menopause after die away, but also develop into cystic hyperplasia, even the ductal epithelium active proliferation, develop into the nipple hypertrophy, cytologic anaplasia and develop into breast carcinoma person.Primary disease is mainly in middle-aged women, also is shown in man and old children.Be main mainly clinically at present, adopt oral methyl testosterone, oral Operand hormone medicines such as (like 5% potassium iodide) with western medical treatment, unsatisfactory curative effect, most of patients can not be cured fully.The traditional Chinese medical science is general to adopt oral RUPIXIAO capsule, but curative effect is relatively poor.

Summary of the invention

The object of the present invention is to provide a kind of Traditional Chinese Medicine for external application of treating cyclomastopathy, main effect for from outward appearance to inner essence, heat-clearing and toxic substances removing, detumescence.

The present invention is achieved in that

The Traditional Chinese Medicine for external application of treatment cyclomastopathy is characterized in that the component of processing effective ingredient by its weight proportion is: Squama Manis 10-20, Rhizoma Paridis 50-100, Semen Sinapis Albae 10-20, succinum 30-60, windproof 10-30 and Radix Glycyrrhizae 10-30.

Hyperplasia of mammary glands is because of the change of feelings will and modern diet structure increases, and the breast local temperature that has is higher than body temperature etc.Facts have proved, utilize traditional Chinese medical science interior disease outer treating method, from outward appearance to inner essence, heat-clearing and toxic substances removing, detumescence, removing obstruction in the collateral to relieve pain.Compare with its traditional therapy, effect obviously and not recurs.Have the high effect of clinical cure rate, cure rate can reach more than 90%; External application is used, instant effect, no pain.

Clinical medicine is thought: periodic mastalgia is the outstanding clinical manifestation of cyclomastopathy; Pain is that pain increases the weight of before many menstruations, through after pain relief, the character of its pain can be prickling-like pain, chronic dull pain; Can tenderness be arranged in the part, also can emit to away side upper arm, alveolus and shoulder.Can contact circular tough and tensile less and diffusing shape lump, most blur margin Chu only contacts zone flat, the increase of granular density, does not also disappear after the menstruation, and pathological changes is sent out top outside breast well.The variation of lump in breast is very big, also is the characteristic of primary disease.Its morbidity maybe be relevant with ovarian dysfunction.

Motherland's traditional medicine thinks that primary disease belongs to Chinese medicine nodules of the breast scope.How being hindered by feelings will, Chong and Ren channel disorder causes.Nipple belongs to the cloudy Liver Channel of sufficient fault, and breast belongs to the stomach channel of foot-Yang-ming.Unsuccessful like feelings will, depressed rage impairing the liver, depression of liver-QI then, the catharsis imbalance, worry impairing spleen, dysfunction of the spleen in transportation, water-damp not being transformed, gather qi together become expectorant, the stagnation of QI, expectorant knot, blood stasis and send out and be lump.The stagnation of QI, expectorant knot, blood stasis be the basic pathogenesis of primary disease just.Few patients and its deficiency of kidney-QI, Chong and Ren channel disorder, so that functional activity of QI being not smooth is relevant.

Among the present invention:

1, Squama Manis: salty, be slightly cold, poisonous.The routed carbuncle of ability detumescence is searched active, the stimulating milk secretion of stimulating the menstrual flow of wind.

2, Rhizoma Paridis: toil, cold, poisonous.The merit that the thermal detoxification of separating is arranged is controlled carbuncle, furuncle scrofula etc.

3, Semen Sinapis Albae: hot, warm." modern practical Chinese medicine ": " mash like mud, be used as the skin irritation rubefacient outward.”

4, succinum: sweet, flat.Nontoxic, dissipating blood stasis hemostasis, treatment skin sore, traumatic injury.

Above-mentioned four flavors are monarch drug.

5, windproof: Xin Gan, temperature.Deliver, dispel the wind, win temperature, pain relieving." not Lu ": " convulsion in the word milk gold skin ulcer.”

6, Radix Glycyrrhizae: sweet, flat, nontoxic.Detoxifcation.Coordinating the actions of various ingredients in a prescription.

Above-mentioned two flavors are ministerial drug.

Selected person in the side, and for reducing swelling and alleviating pain, the dissipating blood stasis carbuncle of bursting, draw table thoroughly in.The combination of the strong compatibility of drugs of holder skin ulcer granulation promoting.In the prescription, the routed carbuncle of Squama Manis detumescence; Search that wind is active, the stimulating milk secretion of stimulating the menstrual flow (stimulating milk secretion explanation meridians are unobstructed); Rhizoma Paridis has the merit of heat-clearing and toxic substances removing; Succinum has the dissipating blood stasis hemostasis, treats skin sore, the merit of traumatic injury.Being equipped with the Semen Sinapis Albae that causes in going into and associating with, is monarch drug altogether, reaches and complements each other, and from outward appearance to inner essence, strengthens the effect of infiltration, dredging the meridian.Windproof in the side, Radix Glycyrrhizae is a ministerial drug, sends out poison, detoxifies, dispels the wind, wins the poison that temperature, pain relieving can be dissolved monarch drug again, and above compatibility brings out the best in each other.

Take a broad view of the present invention, the treatment of primary disease is mainly controlled from faint cloudy Liver Channel and positive yin channel opinion, dispersing liver-energy emphatically, the expectorant knot that looses, the logical stasis of blood stagnates, and holds concurrently to transfer to dash and appoints, and reaches to dwindle or the purpose of dissipation lump.

The specific embodiment

Below in conjunction with embodiment the present invention is elaborated.

Embodiment 1

Manufacture method:

Get Squama Manis 20 grams, Rhizoma Paridis 100 grams, Semen Sinapis Albae 15 grams, succinum 60 grams, grind sieve (280 order) and be powder.Get windproof 20 grams, Radix Glycyrrhizae 30 grams, decocting is agent.Last powder mixing furnishing paste.

Method for using:

Get cream drug of the present invention and spread upon the top, affected part, about 0.2cm-0.3cm thick (getting dorsal position) gets final product with scraps of paper covering, removes after about 4-6 hour (drying).Meet that cold to do bridging type warming.Once, 10 times is a course of treatment next day of general.

Embodiment 2

Get Squama Manis 10 grams, Rhizoma Paridis, 50 grams, Semen Sinapis Albae 10 grams, succinum 30 grams, windproof 10 grams, Radix Glycyrrhizae 10 grams, manufacture method is with embodiment 1.

Embodiment 3

Get Squama Manis 15 grams, Rhizoma Paridis 75 grams, Semen Sinapis Albae 20 grams, succinum 45 grams, windproof 30 grams and Radix Glycyrrhizae 15 grams, manufacture method is with embodiment 1.

Clinical trial

For verifying therapeutic effect of the present invention, county people health hospital has carried out following clinical trial to the present invention to the applicant in the Donga, Shandong Province in 2006-2011:

1, data and method

1.1 diagnostic criteria

1.1.1 Western medicine diagnose standard

With reference to People's Health Publisher " diagnostics " standard, cyclomastopathy belongs to mammary gland benign tumor.Benign tumor then matter is softer.Boundary clear also has certain mobility, and common person has cystic hyperplasia of breast, mammary gland fibroma etc.

1.1.2 tcm diagnosis standard:

With reference to State Administration of Traditional Chinese Medicine's " disease of tcm diagnosis criterion of therapeutical effect " in 1999.1. most in the breast place quadrant one flat lump is arranged, that lays one's hand on has a tough hard tubercle of beans size, and tenderness can be arranged.Owe clearly on the lump border, with the surrounding tissue adhesion.2. breast can have distending pain, and the growth and decline with susceptible to anger whenever increase the weight of before the menstruation of being everlasting, and alleviate after the menstruation.

1.2 physical data

1.2.1 case: according to medical history, clinical symptoms, sign and clinical examination, all case meets the cyclomastopathy diagnostic criteria.Test cyclomastopathy patient 94 examples altogether, the age, the course of disease was in 1 to 4 year in 18-50 year.

1.2.2 divide into groups: above-mentioned patient is divided into two groups at random:

First group is the treatment group, totally 48 examples; Second group is matched group, totally 46 examples.

2, Therapeutic Method

Treatment group external application medicine of the present invention, the next day once, each 5-6 hour, ten times was a course of treatment.

The oral RUPIXIAO capsule of matched group, every day 3 times, each 2.

3, efficacy assessment standard

1. cure: lump in breast and pain disappear.

2. take a turn for the better: lump in breast dwindles, pain relief or disappearance.

3. do not heal: lump in breast and pain no change.

4, efficacy result

4.1 efficacy result synopsis

4.2 clinical symptoms sign synopsis

5, conclusion

Treatment group and matched group are compared, and treatment group cure rate and total effective rate are apparently higher than matched group, and therapeutic effect has significant difference.Therefore medicine of the present invention has significant curative effect to the treatment hyperplasia of mammary glands.

6, concrete case

Case 1:

The Wang.The woman, 31 years old, Donga, Shandong Province from county.Conscious pair of mammary swelling pain, in October, 2009 through scanography: nipple: 28 ℃ of right breasts, 25.8 ℃ of left side breasts, OF2.2 ℃.Impression: cyclomastopathy (right side is heavier).

The treatment: give Drug therapy of the present invention, external application, the next day once.Once applied 5-6 hour.Recovery from illness in 20 days.Paying a return visit after 1 year does not have recurrence.

Case 2:

Grandson.The woman, 35 years old.Donga, Shandong Province county high collection people.Look into: the special enlargement of bimastism, irregular lump is arranged, left side LOQ lump is 15cm * 12cm, right side retracted nipple, no discharge.Be diagnosed as cyclomastopathy through the ultra inspection of coloured silk in March, 2007.External application Drug therapy of the present invention, the next day once, once applied 6 hours, have nipple to eject after the medication three times, 10 recoveries from illness of medication.Paying a return visit after 2 years does not have recurrence.

Case 3:

Dong.The woman, 32 years old.People from Yanggu County, Shandong Province.Readme was suffered from cyclomastopathy 3 years.Pain before each menstrual phase alleviates after the menstrual phase, and pain has not been periodically.In my institute of in JIUYUE, 2010, through looking into: bilateral breast has irregular flat lump, 8.0cm * 12cm, and how 6cm * 10cm goes up quadrant outside, and nipple does not have discharge, and nothing is caved in.The treatment in 20 days of external application medicine of the present invention, recovery from illness.

Claims

1. the Traditional Chinese Medicine for external application of treatment cyclomastopathy is characterized in that the component of processing effective ingredient by its weight proportion is: Squama Manis 10-20, Rhizoma Paridis 50-100, Semen Sinapis Albae 10-20, succinum 30-60, windproof 10-30 and Radix Glycyrrhizae 10-30.

2. the Traditional Chinese Medicine for external application of treatment cyclomastopathy according to claim 1 is characterized in that the weight proportion of said components is: Squama Manis 20, Rhizoma Paridis 100, Semen Sinapis Albae 15, succinum 60, windproof 20 and Radix Glycyrrhizae 30.