CN103157055B - Traditional Chinese medicine preparation for treating hyperplasia of mammary glands - Google Patents
Traditional Chinese medicine preparation for treating hyperplasia of mammary glands Download PDFInfo
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- CN103157055B CN103157055B CN201310086298.8A CN201310086298A CN103157055B CN 103157055 B CN103157055 B CN 103157055B CN 201310086298 A CN201310086298 A CN 201310086298A CN 103157055 B CN103157055 B CN 103157055B
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating hyperplasia of mammary glands. The preparation is composed of the following bulk pharmaceutical chemicals in grams by weight: 20-30g of cornu cervi degelatinatum, 20-30g of poria cocos, 20-30g of epimedium Herb, 15-25g of semen raphani, 15-25g of red flower, 15-25g of honeysuckle, 15-25g of agastache rugosus, 15-25g of rehmannia glutinosa, 10-20g of scorpio, 10-20g of parasitic loranthus, 10-20g of cortex acanthopanacis, 5-15g of cortex Erythrinae, 5-15g of sandalwood, 5-15g of prunella vulgaris, 5-15g of galangal and 5-15g of Chinese mahonia. During treatment, the preparation is orally taken once for every breakfast, lunch and supper everyday by 3g every time. By regarding fifteen days as a course of treatment, two to six courses are generally required for curing. The traditional Chinese medicine preparation for treating hyperplasia of mammary glands provided by the invention has the advantages of scientific and rigorous composition, strong pointedness, good therapeutic and curative effect without toxic side effect. Moreover, the total effective rate is about 94.6 after years of clinical application.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of cyclomastopathy.
Background technology
Cyclomastopathy is one of commonly encountered disease, frequently-occurring disease.Cyclomastopathy is the chronic non-inflammation disease of the one of breast, is apt to occur in 30～40 years old women.Often with menoxenia, infertility or abortion history.In patient's bilateral breast, occur lump not of uniform size, matter is tough not hard, simultaneously normal or generation in succession.Its form or circle or flat, be scattered in breast, or be confined to a certain quadrant.Lump and surrounding tissue divide Jie unclear, not with skin adhesion, and the movement pushing away.Increase the weight of in premenstrual 3-4 of the moon days pain, lump increases.Through after pain relief or disappearance, swollen thing dwindles.Sometimes nipple overflows yellow green, coffee color, bloody fluid.
Cyclomastopathy accounts for the general 75% of all mastopathy, and in the women of child-bearing age, nearly 40% women suffers from cyclomastopathy.In fact cyclomastopathy is divided into two kinds of forms: one is physiological cyclomastopathy, namely women normal physiological changes, this situation is mainly because women of child-bearing age's ovary is in a normal periodically secreting hormone, the at this time target organ of ovary, uterus and mammary gland also present the variation of one-period, just show menstrual cycle as uterus, just show a premenstrual hypertrophy at mammary gland so.Another kind is pathology hypertrophy, and endocrine regulation causes often, because endocrine is affected by several factors, such as mood factor, work aspect, change of life etc., young and middle-aged women rhythm of life is than very fast, the change of living and working environment is also more ordinary, so the generation of cyclomastopathy is higher in this crowd, with the quickening pace of modern life, and life and work pressure strengthens, if neither one well regulates at heart, the sickness rate of cyclomastopathy can present one and increase trend.
Cyclomastopathy occurrence cause, how by depressed rage impairing the liver, stagnation of QI due to depression of the liver, worry impairing spleen, dysfunction of the spleen in transportation, in phlegm-damp, accumulate, liver spleen two is hindered, stagnation of Qi and phelgm, and QI and blood is doubted stagnant, hinders in newborn network, so that nucleation clearly, or deficiency of liver-blood with the passing of time, damage of kidney-YIN, Chong and Ren channel disorder, in deficiency of YIN phlegm-damp due to knot.Modern medicine is thought: the generation of cyclomastopathy is relevant with Progesterone, may be that luteinic secretion reduces, and estrogenic amount relatively increases and causes.Adolescence patient mostly is breast lobule hyperplasia, and the suckling later stage mostly is cyclomastopathy, and climacteric mostly is Cystic hyperplasia of breast.
The harm of cyclomastopathy: breast, the mark of female body building, the second heart of women's life.But because its immunologic function is than low 30% left and right of other organ, so mastopathy is women's commonly encountered diseases, frequently-occurring disease.Up-to-date medical information shows, China has nearly 300,000 women to die from tumor every year, and the death toll of cyclomastopathy canceration accounts for 1/4th of total toll, and breast disease has become the main killer who jeopardizes modern female health.Along with the variation of living environment, cyclomastopathy sickness rate rises very fast, once trouble cyclomastopathy, except pain, lump, patient also has agitation, irritability, fear etc. emotionally, has function reduction on physiology, as indifferent in libido, mottle, menstruation, physically-draining, frequent micturition etc., many with gynaecopathia on pathology, endometriosis etc.This is failed to the comprehensive treating both the principal and secondary aspects of a disease of whole body, control for a long time and more just do not have the danger that transfers breast carcinoma to.
For many years, what western medical treatment cyclomastopathy was conventional has hormones and other symptomatic treatment medicines, but some side effect may appear in the treatment of application androgen, may have liver injury in various degree.Traditional traditional Chinese medical science treats according to dialectical, often adopts the method such as single depressed liver-energy dispersing and QI regulating, resolving depression eliminating stagnation, but the violent medicine treatment of multiplex heavy dose, zest and side effect are very big, and curative effect is also not ideal enough.
Summary of the invention
For above-mentioned prior art, the invention provides a kind of Chinese medicine preparation for the treatment of cyclomastopathy, its therapeutic effect is good, and cost is low, has no side effect.
The present invention is achieved by the following technical solutions:
Treat a Chinese medicine preparation for cyclomastopathy, formed by following crude drug: Cornu Cervi Degelatinatum 20～30g, Poria 20～30g, Herba Epimedii 20～30g, Semen Raphani 15～25g, Flos Carthami 15～25g, Flos Lonicerae 15～25g, Herba Pogostemonis 15～25g, Radix Rehmanniae Preparata 15～25g, Scorpio 10～20g, Herba Taxilli 10～20g, Cortex Acanthopancis 10～20g, Cortex erythrinae 5～15g, Lignum Santali Albi 5～15g, Spica Prunellae 5～15g, Rhizoma Alpiniae Officinarum 5～15g, Mahonia fortunei (Lindl.) Fedde 5～15g.
Preferably, formed by following crude drug: Cornu Cervi Degelatinatum 25g, Poria 25g, Herba Epimedii 25g, Semen Raphani 20g, Flos Carthami 20g, Flos Lonicerae 20g, Herba Pogostemonis 20g, Radix Rehmanniae Preparata 20g, Scorpio 15g, Herba Taxilli 15g, Cortex Acanthopancis 15g, Cortex erythrinae 10g, Lignum Santali Albi 10g, Spica Prunellae 10g, Rhizoma Alpiniae Officinarum 10g, Mahonia fortunei (Lindl.) Fedde 10g.
The preparation method of the Chinese medicine preparation of described treatment cyclomastopathy is: get each crude drug, pulverize as powdery, cross 200 mesh sieves, mix, make powder, capsule, electuary, tablet or pill, to obtain final product.Preferably capsule.
The Chinese medicine preparation for the treatment of cyclomastopathy of the present invention, mainly for treating mammary gland hypertrophy (being applicable to the large and small leaf hypertrophy of mammary gland, human milk silt etc.), when treatment, oral, morning, noon and afternoon every day respectively once, each serving with 3g left and right (pressing medicated powder Mass Calculation), within 15 days, be a course for the treatment of, can cure general 2～6 courses for the treatment of.
The Chinese medicine preparation for the treatment of cyclomastopathy of the present invention, prescription scientific and precise, specific aim is more intense, can improve blood flow volume, reduces peripheral vascular resistance, improve blood circulation, blood vessel dilating wall, reduce blood viscosity, anticoagulant, promotes fibrinolysis, promotes the formation of hemolytic antibody, can suppress fibrocellular growth and propagation, reduce radioactive proliferation of fibrous tissue.The cellular immune function of enhancing body, the oxidation of anticancer and dehydrogenation, antitumor.There are certain defying age, antiviral, antitumaous effect.There is the effects such as vegetables liver resolving depression, activating QI to eliminate phlegm, dredge the meridian passage, reducing swelling and alleviating pain, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, removing mass dispersing tumor, mainly for treating mammary gland hypertrophy, cyclomastopathy, lump in breast, Breast pain etc., therapeutic effect is good, through clinical application for many years, total effective rate is in 94.6 left and right, curative effect is very good, and has no side effect.
Detailed description of the invention
Below in conjunction with embodiment and clinical data, the present invention is further illustrated.
The Chinese medicine preparation of embodiment 1 preparation treatment cyclomastopathy
Formula is: Cornu Cervi Degelatinatum 25g, Poria 25g, Herba Epimedii 25g, Semen Raphani 20g, Flos Carthami 20g, Flos Lonicerae 20g, Herba Pogostemonis 20g, Radix Rehmanniae Preparata 20g, Scorpio 15g, Herba Taxilli 15g, Cortex Acanthopancis 15g, Cortex erythrinae 10g, Lignum Santali Albi 10g, Spica Prunellae 10g, Rhizoma Alpiniae Officinarum 10g, Mahonia fortunei (Lindl.) Fedde 10g.
Preparation method is: get each crude drug, pulverize as powdery, cross 200 mesh sieves, mix, obtain medicated powder, pack No. 1 capsule into and make capsule.
When treatment, oral, morning, noon and afternoon every day respectively once, each serving with 3g left and right (pressing medicated powder Mass Calculation), 15 days are a course for the treatment of, and can cure general 2～6 courses for the treatment of.
The Chinese medicine preparation of embodiment 2 preparation treatment cyclomastopathy
Formula is: Cornu Cervi Degelatinatum 22g, Poria 22g, Herba Epimedii 28g, Semen Raphani 23g, Flos Carthami 18g, Flos Lonicerae 18g, Herba Pogostemonis 23g, Radix Rehmanniae Preparata 23g, Scorpio 12g, Herba Taxilli 12g, Cortex Acanthopancis 18g, Cortex erythrinae 13g, Lignum Santali Albi 8g, Spica Prunellae 8g, Rhizoma Alpiniae Officinarum 13g, Mahonia fortunei (Lindl.) Fedde 13g.
Preparation method is with embodiment 1.
The Chinese medicine preparation of embodiment 3 preparation treatment cyclomastopathy
Formula is: Cornu Cervi Degelatinatum 28g, Poria 28g, Herba Epimedii 22g, Semen Raphani 18g, Flos Carthami 23g, Flos Lonicerae 23g, Herba Pogostemonis 18g, Radix Rehmanniae Preparata 18g, Scorpio 18g, Herba Taxilli 18g, Cortex Acanthopancis 12g, Cortex erythrinae 8g, Lignum Santali Albi 13g, Spica Prunellae 13g, Rhizoma Alpiniae Officinarum 8g, Mahonia fortunei (Lindl.) Fedde 8g.
Preparation method is with embodiment 1.
The Chinese medicine preparation of embodiment 4 preparation treatment cyclomastopathy
Formula is: Cornu Cervi Degelatinatum 20g, Poria 30g, Herba Epimedii 20g, Semen Raphani 25g, Flos Carthami 15g, Flos Lonicerae 25g, Herba Pogostemonis 15g, Radix Rehmanniae Preparata 25g, Scorpio 10g, Herba Taxilli 20g, Cortex Acanthopancis 10g, Cortex erythrinae 15g, Lignum Santali Albi 5g, Spica Prunellae 15g, Rhizoma Alpiniae Officinarum 5g, Mahonia fortunei (Lindl.) Fedde 15g.
Preparation method is with embodiment 1.
The Chinese medicine preparation of embodiment 5 preparation treatment cyclomastopathy
Formula is: Cornu Cervi Degelatinatum 30g, Poria 20g, Herba Epimedii 30g, Semen Raphani 15g, Flos Carthami 25g, Flos Lonicerae 15g, Herba Pogostemonis 25g, Radix Rehmanniae Preparata 15g, Scorpio 20g, Herba Taxilli 10g, Cortex Acanthopancis 20g, Cortex erythrinae 5g, Lignum Santali Albi 15g, Spica Prunellae 5g, Rhizoma Alpiniae Officinarum 15g, Mahonia fortunei (Lindl.) Fedde 5g.
Preparation method is with embodiment 1.
Clinical data:
Patient's data: 215 routine patients all suffer from cyclomastopathy, wherein, between 20～45 years old age, average 31 years old, the course of disease was the longest 6 years, the shortest person half a year.Be divided at random matched group and treatment group, matched group 86 examples, treatment group 129 examples, between two groups without significant difference.
Diagnostic criteria: " disease of tcm Standardization of diagnosis and curative effect " ZY/T001.2-94 promulgating by State Administration of Traditional Chinese Medicine and diagnosis reference standard (the 8th meeting of Chinese surgery of Chinese medicine breast disease Professional Committee of association in 2002 passed through).And get rid of breast carcinoma, mammary gland fibroma or other mastopathy person in conjunction with computer infrared mammary gland somascope, color ultrasound or pathology auxiliary diagnosis.
Therapeutic modality: matched group adopts RUKANG PIAN to treat, every day three times, each two.Treatment group adopts medicine of the present invention to treat (medicine prepared by embodiment 1), oral, and morning, noon and afternoon every day respectively once, each serving with 3g (pressing crude drug medicated powder Mass Calculation), 15 days are a course for the treatment of.Treat observe the curative effect after two months.
Result: treat after three courses for the treatment of matched group: in 86 routine patients, cure 42 examples, effective 29 examples, invalid 15 examples, cure rate is 48.8%, and total effective rate is 82.6%.
Treatment group: in 129 routine patients, cure 90 examples, effective 32 examples, invalid 7 examples, cure rate is 69.8%, and total effective rate is 94.6%; Hemorheology index after treatment: whole blood viscosity, packed cell volume, Fibrinogen all obviously decline, and during treatment, patient all has no adverse reaction.
Case 1: thank so-and-so, female, 31 years old, right distending pain of the breast discomfort, before menstrual phase, 7～10 days distending pains obviously increase the weight of.Ultrasound diagnosis cyclomastopathy.Through multi-treatment, poor effect.Adopt the medicine of embodiment 1 to treat, oral, morning, noon and afternoon every day respectively once, each serving with 3g left and right (pressing medicated powder Mass Calculation), 15 days are a course for the treatment of, and after one week, distending pain discomfort alleviates, and after the course for the treatment of, do not have distending pain obviously to increase the weight of sensation.After three courses for the treatment of, symptom disappears completely.Two courses for the treatment of of continual cure are to consolidate curative effect.Within 1 year, pay a return visit afterwards, have no recurrence.
Case 2: insult so-and-so, female, 38 years old, two newborn swelling pain, had lump, and the moon swells and ache and obviously increases the weight of for premenstrual 7～8 days, is diagnosed as cyclomastopathy.Adopt the medicine of embodiment 1 to treat, oral, morning, noon and afternoon every day respectively once, each serving with 3g left and right (pressing medicated powder Mass Calculation), 15 days are a course for the treatment of; After two courses for the treatment of, all transference cures, cure.A course for the treatment of of continual cure is to consolidate curative effect.After half a year, pay a return visit, have no recurrence.
Case 3: shut out so-and-so, female, 35 years old, two swelling of the breast pieces companion pain more than 8 years, more so premenstrual, pain connects and two upper limb and back, two breasts top, can touch block body of gland down, and tenderness, is diagnosed as cyclomastopathy.Adopt the medicine of embodiment 1 to treat, oral, morning, noon and afternoon every day respectively once, each serving with 3g left and right (pressing medicated powder Mass Calculation), 15 days are a course for the treatment of; After four courses for the treatment of, pain disappears, and lump disappears, and cures.Two courses for the treatment of of continual cure are to consolidate curative effect.Within 1 year, pay a return visit afterwards, have no recurrence.
Claims (5)
1. a Chinese medicine preparation for the treatment of cyclomastopathy, is characterized in that: be made up of following crude drug: Cornu Cervi Degelatinatum 20～30g, Poria 20～30g, Herba Epimedii 20～30g, Semen Raphani 15～25g, Flos Carthami 15～25g, Flos Lonicerae 15～25g, Herba Pogostemonis 15～25g, Radix Rehmanniae Preparata 15～25g, Scorpio 10～20g, Herba Taxilli 10～20g, Cortex Acanthopancis 10～20g, Cortex erythrinae 5～15g, Lignum Santali Albi 5～15g, Spica Prunellae 5～15g, Rhizoma Alpiniae Officinarum 5～15g, Mahonia fortunei (Lindl.) Fedde 5～15g.
2. a kind of Chinese medicine preparation for the treatment of cyclomastopathy according to claim 1, is characterized in that: be made up of following crude drug: Cornu Cervi Degelatinatum 25g, Poria 25g, Herba Epimedii 25g, Semen Raphani 20g, Flos Carthami 20g, Flos Lonicerae 20g, Herba Pogostemonis 20g, Radix Rehmanniae Preparata 20g, Scorpio 15g, Herba Taxilli 15g, Cortex Acanthopancis 15g, Cortex erythrinae 10g, Lignum Santali Albi 10g, Spica Prunellae 10g, Rhizoma Alpiniae Officinarum 10g, Mahonia fortunei (Lindl.) Fedde 10g.
3. a kind of Chinese medicine preparation for the treatment of cyclomastopathy according to claim 1, is characterized in that: be made up of following crude drug: Cornu Cervi Degelatinatum 22g, Poria 22g, Herba Epimedii 28g, Semen Raphani 23g, Flos Carthami 18g, Flos Lonicerae 18g, Herba Pogostemonis 23g, Radix Rehmanniae Preparata 23g, Scorpio 12g, Herba Taxilli 12g, Cortex Acanthopancis 18g, Cortex erythrinae 13g, Lignum Santali Albi 8g, Spica Prunellae 8g, Rhizoma Alpiniae Officinarum 13g, Mahonia fortunei (Lindl.) Fedde 13g.
4. a kind of Chinese medicine preparation for the treatment of cyclomastopathy according to claim 1, is characterized in that: be made up of following crude drug: Cornu Cervi Degelatinatum 28g, Poria 28g, Herba Epimedii 22g, Semen Raphani 18g, Flos Carthami 23g, Flos Lonicerae 23g, Herba Pogostemonis 18g, Radix Rehmanniae Preparata 18g, Scorpio 18g, Herba Taxilli 18g, Cortex Acanthopancis 12g, Cortex erythrinae 8g, Lignum Santali Albi 13g, Spica Prunellae 13g, Rhizoma Alpiniae Officinarum 8g, Mahonia fortunei (Lindl.) Fedde 8g.
5. the preparation method of the Chinese medicine preparation of the treatment cyclomastopathy described in any one in claim 1～4, is characterized in that: get each crude drug, pulverize as powdery, cross 200 mesh sieves, mix, make powder, capsule, electuary, tablet or pill, to obtain final product.
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| CN201310086298.8A CN103157055B (en) | 2013-03-18 | 2013-03-18 | Traditional Chinese medicine preparation for treating hyperplasia of mammary glands |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105168989A (en) * | 2015-07-29 | 2015-12-23 | 郭学敏 | Traditional Chinese medicinal decoction for clearing heat and inducing diuresis |
| CN106110209A (en) * | 2016-08-09 | 2016-11-16 | 李双双 | A kind of Chinese medicine preparation treating cyclomastopathy |
| CN106390035A (en) * | 2016-11-16 | 2017-02-15 | 魏广景 | Traditional Chinese medicine preparation for treating mammary gland hyperplasia |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1931301A (en) * | 2006-09-29 | 2007-03-21 | 毛志中 | Chinese medicine prepn for treating mastoproliferation and its prepn process |
| CN102309728A (en) * | 2011-09-26 | 2012-01-11 | 兰州大学第一医院 | Medicine for treating hyperplasia of mammary glands, mastodynia and general mammary diseases and preparation method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1931301A (en) * | 2006-09-29 | 2007-03-21 | 毛志中 | Chinese medicine prepn for treating mastoproliferation and its prepn process |
| CN102309728A (en) * | 2011-09-26 | 2012-01-11 | 兰州大学第一医院 | Medicine for treating hyperplasia of mammary glands, mastodynia and general mammary diseases and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 中医治疗乳腺增生病近况;周家萍;《广西中医药》;20050430;第28卷(第2期);6-9 * |
| 周家萍.中医治疗乳腺增生病近况.《广西中医药》.2005,第28卷(第2期), |
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