CN103920100B - A kind of pharmaceutical composition treating cyclomastopathy - Google Patents
A kind of pharmaceutical composition treating cyclomastopathy Download PDFInfo
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- CN103920100B CN103920100B CN201410195818.3A CN201410195818A CN103920100B CN 103920100 B CN103920100 B CN 103920100B CN 201410195818 A CN201410195818 A CN 201410195818A CN 103920100 B CN103920100 B CN 103920100B
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- 239000003814 drug Substances 0.000 claims abstract description 21
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- 235000011201 Ginkgo Nutrition 0.000 claims abstract description 13
- 235000008100 Ginkgo biloba Nutrition 0.000 claims abstract description 13
- 210000000582 semen Anatomy 0.000 claims abstract description 13
- 241001521474 Liriope <hydrozoan> Species 0.000 claims abstract description 12
- 239000002994 raw material Substances 0.000 claims abstract description 10
- 239000002775 capsule Substances 0.000 claims abstract description 7
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 238000002360 preparation method Methods 0.000 claims description 10
- 229940079593 drug Drugs 0.000 claims description 8
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- 208000019255 Menstrual disease Diseases 0.000 abstract description 3
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- 239000007788 liquid Substances 0.000 abstract description 3
- 206010006223 Breast discharge Diseases 0.000 abstract description 2
- 238000009835 boiling Methods 0.000 abstract description 2
- 230000005802 health problem Effects 0.000 abstract description 2
- 210000003026 hypopharynx Anatomy 0.000 abstract description 2
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- 230000036407 pain Effects 0.000 description 4
- 206010020880 Hypertrophy Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
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- 206010020718 hyperplasia Diseases 0.000 description 2
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- 210000001519 tissue Anatomy 0.000 description 2
- 206010006272 Breast mass Diseases 0.000 description 1
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
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Abstract
The invention discloses a kind of pharmaceutical composition treating cyclomastopathy, be made up of the raw material of following weight: Bulbus Fritillariae Cirrhosae 20 40 parts, Bulbus Lilii 10 20 parts, Periostracum Cicadae 3 12 parts, Fructus Malvae 15 25 parts, Radix Physochlainae 5 10 parts, Fructus Ligustri Lucidi 10 20 parts, Radix Liriopes 20 40 parts, the Fructus Kochiae 10 18 parts, Semen Euphorbiae 15 20 parts, Herba Eupatorii 15 25 parts, Radix Curcumae 10 14 parts, Folium Ginkgo 10 15 parts.This medicine can alleviate the clinical symptoms such as mastalgia that cyclomastopathy causes, lump in breast, nipple discharge, menoxenia, will change timely, effectively improve the health problem of breast, instant effect, difficulty in relapse after healing, there is not any side effect, tablet or capsule taking convenience in pure Chinese medicine, it is to avoid boiling of Chinese medicine, and Liquid traditional Chinese medicine is bitter, taste is big, it has not been convenient to take and the problem of more difficult hypopharynx.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of pharmaceutical composition treating cyclomastopathy.
Background technology
Cyclomastopathy is the modal cystic hyperplasia of breast of women, refers to breast epithelium and proliferation of fibrous tissue, and mammary gland tissue conduit and breast are little
Leaf degeneration structurally and the growth of Progressive symmetric erythrokeratodermia connective tissue, its clinical symptoms mainly shows as mastalgia, breast
Lump, nipple discharge, menoxenia, will change etc..
Direct stimulation can change human internal environment, thus affects hormonal system function, causes the secretion of a certain or several hormone
Occur abnormal.The bad Nervous and Mental Factors such as spirit is excessively nervous, emotion is excessively exciting, all may make the mammary gland that should restore increase
Raw tissue can not get restoring or meromorphosis, in the course of time, just forms cyclomastopathy, and these bad direct stimulations also can
Increase the weight of existing cyclomastopathy symptom.Additionally dietary structure is unreasonable, as fat intake is too much, can affect the endocrine of ovary,
Strengthen the stimulation of estrogen on breast epithelial cell thus cause cyclomastopathy.Also have many anthropic factors and Lifestyle factors,
Artificial abortion, fertility or fertility in more than 30 years old, not suckling, man and wife gets along well, and the medicated bra of tension worn by health product containing hormone etc.,
The medicated bra of tension easily oppresses lymph and blood circulation, all hinders Breast health.
Along with the operating pressure of working woman is increasing, and the worry brought in family, cause increasing women to suffer from
Cyclomastopathy, at present, the Therapeutic Method of Domestic Medicine bound pair cyclomastopathy substantially has two kinds: operative therapy and pharmacotherapy.Hands
Art is treated the most costly, and brings misery and postoperative generation stasis of blood trace to directly influence outside breast to patient over the course for the treatment of
Shape and attractive in appearance.Treat mastotic medicine at present a lot, although there is certain curative effect, but cannot thoroughly effect a radical cure, easily recur,
Mammary gland patient medication is caused just to take a turn for the better, drug withdrawal situation the most repeatedly, increase the chance of patient's canceration, allow patient lose treatment
Confidence.
Summary of the invention
It is an object of the invention to provide a kind of pharmaceutical composition treating cyclomastopathy, said composition is made with pure Chinese medicine, this medicine mark
This is the most double controls, instant effect, have no side effect, difficulty in relapse after healing, cyclomastopathy is had fabulous curative effect.
For achieving the above object, the present invention is achieved by the following technical solutions:
A kind of pharmaceutical composition treating cyclomastopathy, it is made up of the raw material of following weight: Bulbus Fritillariae Cirrhosae 20-40 part,
Bulbus Lilii 10-20 part, Periostracum Cicadae 3-12 part, Fructus Malvae 15-25 part, Radix Physochlainae 5-10 part, Fructus Ligustri Lucidi 10-20 part, Radix Liriopes
20-40 part, Fructus Kochiae 10-18 part, Semen Euphorbiae 15-20 part, Herba Eupatorii 15-25 part, Radix Curcumae 10-14 part, Folium Ginkgo 10-15
Part.
Preferably, a kind of pharmaceutical composition treating cyclomastopathy, it is made up of the raw material of following weight: Bulbus Fritillariae Cirrhosae 30-35
Part, Bulbus Lilii 15-20 part, Periostracum Cicadae 5-10 part, Fructus Malvae 20-25 part, Radix Physochlainae 6-9 part, Fructus Ligustri Lucidi 15-18 part, mountain wheat
Winter 25-35 part, Fructus Kochiae 12-16 part, Semen Euphorbiae 16-18 part, Herba Eupatorii 18-20 part, Radix Curcumae 10-12 part, Folium Ginkgo
10-12 part.
Preferably, a kind of pharmaceutical composition treating cyclomastopathy, it is made up of the raw material of following weight: Bulbus Fritillariae Cirrhosae 33
Part, Bulbus Lilii 16 parts, Periostracum Cicadae 8 parts, Fructus Malvae 22 parts, Radix Physochlainae 8 parts, Fructus Ligustri Lucidi 17 parts, Radix Liriopes 30 parts, ground
15 parts of skin, Semen Euphorbiae 17 parts, Herba Eupatorii 18 parts, Radix Curcumae 11 parts, Folium Ginkgo 12 parts.
Preferably, a kind of pharmaceutical composition treating cyclomastopathy, it is made up of the raw material of following weight: Bulbus Fritillariae Cirrhosae 30
Part, Bulbus Lilii 15 parts, Periostracum Cicadae 8 parts, Fructus Malvae 20 parts, Radix Physochlainae 7 parts, Fructus Ligustri Lucidi 15 parts, Radix Liriopes 30 parts, ground
16 parts of skin, Semen Euphorbiae 16 parts, Herba Eupatorii 20 parts, Radix Curcumae 12 parts, Folium Ginkgo 10 parts.
The preparation method of the pharmaceutical composition of described treatment cyclomastopathy is: take each crude drug, mixing, adds 8~10 times amount (weight
Amount multiple) water, decoct 1-2 hour, filter to get filtrate, in medicinal residues, add the water of 4-6 times amount (weight multiple) again, decoct 1-1.5
Hour, filtering to get filtrate, merge twice filtrate, conventional vacuum concentrates, is dried to obtain fine powder, makes tablet or capsule, to obtain final product.
The using method of the pharmaceutical composition of described treatment cyclomastopathy: daily two or two panels, point morning and evening warm water takes,
It within 10th, it is a course for the treatment of.
Beneficial effects of the present invention: this medicine can alleviate mastalgia that cyclomastopathy causes timely, lump in breast, nipple overflow
The clinical symptoms such as liquid, menoxenia, will change, effectively improve the health problem of breast, instant effect, difficulty in relapse after healing,
There is not any side effect, tablet or capsule taking convenience in pure Chinese medicine, it is to avoid boiling of Chinese medicine, and Liquid traditional Chinese medicine is bitter,
Taste is big, it has not been convenient to take and the problem of more difficult hypopharynx.
Detailed description of the invention
Embodiment 1
The pharmaceutical composition of preparation treatment cyclomastopathy, formula is: Bulbus Fritillariae Cirrhosae 33g, Bulbus Lilii 16g, Periostracum Cicadae 8g, Fructus Malvae 22
G, Radix Physochlainae 8g, Fructus Ligustri Lucidi 17g, Radix Liriopes 30g, Fructus Kochiae 15g, Semen Euphorbiae 17g, Herba Eupatorii 18g, Radix Curcumae 11g,
Folium Ginkgo 12g.
Preparation method is: take each crude drug, mixing, adds 9 times amount water, decocts 1.5 hours, filter to get filtrate, in medicinal residues
Adding the water of 5 times amount again, decoct 1 hour, filter to get filtrate, merge twice filtrate, conventional vacuum concentrates, is dried to obtain fine powder,
Make capsule, to obtain final product.
Embodiment 2
The pharmaceutical composition of preparation treatment cyclomastopathy, formula is: Bulbus Fritillariae Cirrhosae 30g, Bulbus Lilii 10g, Periostracum Cicadae 3g, Fructus Malvae 15
G, Radix Physochlainae 7g, Fructus Ligustri Lucidi 10g, Radix Liriopes 20g, Fructus Kochiae 10g, Semen Euphorbiae 15g, Herba Eupatorii 15g, Radix Curcumae 10g,
Folium Ginkgo 10g.
Preparation method is: take each crude drug, mixing, adds 9 times amount water, decocts 1.5 hours, filter to get filtrate, in medicinal residues
Adding the water of 5 times amount again, decoct 1 hour, filter to get filtrate, merge twice filtrate, conventional vacuum concentrates, is dried to obtain fine powder,
Make tablet, to obtain final product.
Embodiment 3
The pharmaceutical composition of preparation treatment cyclomastopathy, formula is: Bulbus Fritillariae Cirrhosae 30g, Bulbus Lilii 20g, Periostracum Cicadae 12g, Fructus Malvae
25g, Radix Physochlainae 5g, Fructus Ligustri Lucidi 20g, Radix Liriopes 40g, Fructus Kochiae 18g, Semen Euphorbiae 20g, Herba Eupatorii 25g, Radix Curcumae 14
G, Folium Ginkgo 15g.
Preparation method is: take each crude drug, mixing, adds 9 times amount water, decocts 1.5 hours, filter to get filtrate, in medicinal residues
Adding the water of 5 times amount again, decoct 1 hour, filter to get filtrate, merge twice filtrate, conventional vacuum concentrates, is dried to obtain fine powder,
Make capsule, to obtain final product.
Embodiment 4
Preparation treatment cyclomastopathy pharmaceutical composition, formula is: a kind of pharmaceutical composition treating cyclomastopathy, it be by with
The raw material of lower weight is made: Bulbus Fritillariae Cirrhosae 35g, Bulbus Lilii 15g, Periostracum Cicadae 8g, Fructus Malvae 20g, Radix Physochlainae 10g, female
Loyal sub-15g, Radix Liriopes 30g, Fructus Kochiae 16g, Semen Euphorbiae 16g, Herba Eupatorii 20g, Radix Curcumae 12g, Folium Ginkgo 10g.
Preparation method is: take each crude drug, mixing, adds 9 times amount water, decocts 1.5 hours, filter to get filtrate, in medicinal residues
Adding the water of 5 times amount again, decoct 1 hour, filter to get filtrate, merge twice filtrate, conventional vacuum concentrates, is dried to obtain fine powder,
Make tablet, to obtain final product.
Clinical data
360 examples are female patient, minimum 22 years old of age, maximum 55 years old, wherein 22-29 year 60 examples, 30-40 year 210 examples,
More than 40 years old 90 examples, the course of disease 3 months-5 years, hypertrophy lump is distributed at mammary gland difference quadrant, with the outside upper quadrant of double breasts relatively
Common, cyclomastopathy 190 example in 360 examples, fibroplasia 60 example, cystic hyperplasia 10 example.
Therapeutic Method: the pharmaceutical composition for the treatment of cyclomastopathy prepared by all selected patients daily two or this invention of two panels,
Dividing warm water sooner or later to take, one after each meal, 10th is a course for the treatment of.
Criterion of therapeutical effect
Curing: clinical symptom disappearance, lump eliminates;Effective: transference cure, more than mass reduction l/2;It is effective: lump deliquescing,
Reduce less than l/2, and mastalgia alleviates earlier above after still having tenderness, premenstruum and fatigue;Invalid: unchanged before and after treatment.
Therapeutic outcome
Cure 230 examples, effective 40 examples, effective 60 examples, invalid 30 examples, total effective rate 91.7%.
Model case:
Case 1, poplar, female, 30 years old, patient's private prosecution: found before 3 months that double breast all differs in size enclosed mass lump, often
Double mammary swellings pains during secondary menstrual onset, and enclosed mass has increase, through after pain relief or disappearance, although but enclosed mass reduce and still will not disappear
Lose.Left and right breast is outer as the enclosed mass that all differs in size, and hard in matter, smooth surface, mobility is good, and tenderness is obvious.Bilateral breast
Gland skin is normal, and nipple is without depression and discharge.Ultrasound diagnosis: bilateral breast lobule fibroid hypertrophy.Breast target x-ray checks:
Double cyclomastopathy.Gonadal hormone checks abnormal.Through taking 3 courses for the treatment of of medicine composite for curing of the present invention, menstrual onset menstrual period
Distending pain of the breast do not occur, go on 6 courses for the treatment of, all diseases are known and are removed.Follow up a case by regular visits to not recur in 1 year.
Case 2, Mulberry, female, 35 years old, patient's readme: the most spiritual the most gloomy, susceptible to lose temper due to restlessness, particularly menstrual onset
Before, sensation bimastism has a lump afterwards, and has the trend of increase, both sides distending pain of the breast between moon paramenstrum, even spinosity
Aching, and lump in breast increases with the fluctuation of breast feelings will, spirit is gloomy, sensation of oppression over the chest with shortness of breath, is diagnosed as mammary gland capsule through examination in hospital
Hypertrophy disease, fullys recover from an illness after taking 4 courses for the treatment of of Chinese medicine composition of the present invention
More.
With clinical data, the detailed description of the invention of the present invention is described although above-mentioned in conjunction with the embodiments, but not to the present invention
The restriction of protection domain, one of ordinary skill in the art should be understood that on the basis of technical scheme, art technology
Personnel need not to pay various amendments or deformation that creative work can make still within protection scope of the present invention.
Claims (5)
1. the pharmaceutical composition treating cyclomastopathy, it is characterised in that be made up of the raw material of following weight: Bulbus Fritillariae Cirrhosae 20-40 part, Bulbus Lilii 10-20 part, Periostracum Cicadae 3-12 part, Fructus Malvae 15-25 part, Radix Physochlainae 5-10 part, Fructus Ligustri Lucidi 10-20 part, Radix Liriopes 20-40 part, Fructus Kochiae 10-18 part, Semen Euphorbiae 15-20 part, Herba Eupatorii 15-25 part, Radix Curcumae 10-14 part, Folium Ginkgo 10-15 part.
2. the pharmaceutical composition of the treatment cyclomastopathy as described in claim 1, it is characterised in that be made up of the raw material of following weight: Bulbus Fritillariae Cirrhosae 30-35 part, Bulbus Lilii 15-20 part, Periostracum Cicadae 5-10 part, Fructus Malvae 20-25 part, Radix Physochlainae 6-9 part, Fructus Ligustri Lucidi 15-18 part, Radix Liriopes 25-35 part, Fructus Kochiae 12-16 part, Semen Euphorbiae 16-18 part, Herba Eupatorii 18-20 part, Radix Curcumae 10-12 part, Folium Ginkgo 10-12 part.
3. the pharmaceutical composition of the treatment cyclomastopathy as described in claim 1, it is characterised in that be made up of the raw material of following weight: Bulbus Fritillariae Cirrhosae 33 parts, Bulbus Lilii 16 parts, Periostracum Cicadae 8 parts, Fructus Malvae 22 parts, Radix Physochlainae 8 parts, Fructus Ligustri Lucidi 17 parts, Radix Liriopes 30 parts, the Fructus Kochiae 15 parts, Semen Euphorbiae 17 parts, Herba Eupatorii 18 parts, Radix Curcumae 11 parts, Folium Ginkgo 12 parts.
4. the pharmaceutical composition of the treatment cyclomastopathy as described in claim 1, it is characterised in that be made up of the raw material of following weight: Bulbus Fritillariae Cirrhosae 30 parts, Bulbus Lilii 15 parts, Periostracum Cicadae 8 parts, Fructus Malvae 20 parts, Radix Physochlainae 7 parts, Fructus Ligustri Lucidi 15 parts, Radix Liriopes 30 parts, the Fructus Kochiae 16 parts, Semen Euphorbiae 16 parts, Herba Eupatorii 20 parts, Radix Curcumae 12 parts, Folium Ginkgo 10 parts.
5. as described in claim 1-4 is arbitrary, treat the preparation method of the pharmaceutical composition of cyclomastopathy, it is characterised in that take each crude drug, mixing, adds weight multiple 8-10 times amount water, decocts 1-2 hour, filter to get filtrate, in medicinal residues, add the water of weight multiple 4-6 times amount again, decoct 1-1.5 hour, filter to get filtrate, merge twice filtrate, conventional vacuum concentrates, is dried to obtain fine powder, makes tablet or capsule, to obtain final product.
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1334114A (en) * | 2001-08-09 | 2002-02-06 | 宋崇淑 | Chinese medicine for treating mastoplasia |
US20130028968A1 (en) * | 2011-07-29 | 2013-01-31 | Andy Teh-An Huang | Compositions and methods to relieve chronic diseases symptoms |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN1334114A (en) * | 2001-08-09 | 2002-02-06 | 宋崇淑 | Chinese medicine for treating mastoplasia |
US20130028968A1 (en) * | 2011-07-29 | 2013-01-31 | Andy Teh-An Huang | Compositions and methods to relieve chronic diseases symptoms |
Non-Patent Citations (3)
Title |
---|
中医药研究乳腺增生症概况;程群等;《光明中医》;20031231;第18卷(第108期);第21-22页 * |
丹栀逍遥散加减治疗乳腺增生病62例;周晓;《福建中医药》;20081031;第39卷(第5期);第38页 * |
疏肝补肾法治疗乳腺增生;王丽红;《广西中医药》;20070630;第30卷(第3期);第22页 * |
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