CN103933475B - A kind of pharmaceutical composition treating mammary gland fibroma and its production and use - Google Patents
A kind of pharmaceutical composition treating mammary gland fibroma and its production and use Download PDFInfo
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Abstract
The invention provides a kind of pharmaceutical composition treating mammary gland fibroadenoma, it is the medicament being prepared from by the crude drug of following weight proportioning: Radix Salviae Miltiorrhizae 15~18 parts, Radix Angelicae Sinensis 12~15 parts, Radix Scrophulariae 15~18 parts, Spica Prunellae 12~15 parts, Fructus Forsythiae 12~15 parts, Semen Persicae 10~12 parts, Flos Carthami 6~9 parts, Rhizoma Chuanxiong 4~6 parts, Rhizoma Bolbostematis 10~12 parts, Concha Ostreae 25~30 parts, Rhizoma Cyperi 8~10 parts, Radix Curcumae 8~10 parts, Radix Bupleuri 8~10 parts, the Radix Paeoniae Alba 8~10 parts, Radix Platycodonis 4~6, Radix Achyranthis Bidentatae 8~10 parts, Radix Glycyrrhizae 4~6 parts.Present invention also offers preparation method and the purposes of this pharmaceutical composition.Drug regimen composition formula of the present invention is precise and appropriate, can effectively treat mammary gland fibroadenoma (or alleviating its patient's condition), and avoid the toxic and side effects that chemical drugs is had, provide a kind of new selection for clinical application.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition treating mammary gland fibroma.Belong to drug world.
Background technology
Mammary gland fibroadenoma is frequently referred to mastofibroma clinically, is to betide fibrous tissue and gland in mammary glands in women lobule
The Combination tumor of epithelium, is a kind of modal excision of benign breast.The generation of mastofibroma has with endocrine hormone imbalance
Closing, relatively or definitely raise such as estrogen and can cause primary disease, its reason is the fibrocyte sensitivity to estrogen in lobule
Extremely increasing, this may be relevant with the exception of the amount of estrogen receptor contained by fibrocyte or matter.Estrogen is that primary disease occurs
Stimulating factor, therefore its after i.e. betiding ovarian function phase, i.e. adolescence the women at any age all can fall ill, it is desirable that send out in
Its sexual function vigorous period, thus 18~the young women of 25 years old the most common.
Mastofibroma is apt to occur in the outside upper quadrant of breast, and about 75% is single-shot, minority belong to multiple (simultaneously or different
Time).In addition to there is lump, patient is generally without obvious subjective symptoms.Though mammary gland fibroadenoma belongs to optimum, but has the possibility that cancerates,
Therefore once find, i.e. should active treatment.As a rule, lump in breast is the only symptom of primary disease, and its lump mostly is trouble
Person is found unintentionally, the most painless, does not changes with menstrual cycle, but the mammary gland fiber gland of small part patient
Tumor exists jointly with cyclomastopathy, and this situation then can have premenstrual distending pain of the breast.
Though adenofibroma of breast belongs to optimum, but has the possibility that cancerates, add uncertain danger to patient, therefore should be positive
Treatment.Western medical treatment mastofibroma one is excision, and two is hormonotherapy., excision not only makes patient by one
The hardship of cutter, and relapse rate is the highest, and often other positions at breast occur again;And hormone therapy, can produce again serious
Toxic and side effects.
On the whole mastofibroma is equivalent to the diseases such as " nodules of the breast ", " nodule in the breast " of the traditional Chinese medical science, also has and is called " breast scrofula ", the traditional Chinese medical science
Tackle its way from ancient times the most rich and varied and curative effect reliable, and have an at least two thousand years put into practice history.By determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, can
To make different therapeutic rule;By the scientific compatibility of " medication is such as used military forces ", group different effective good recipes can be made.Remove
Outside this, also acupuncture and tuina-massage and assorted style therapy among the people, all can produce good effect.Thus, in treatment, undoubtedly than doctor trained in Western medicine
Resourcefulness and green natural and have no side effect.
Summary of the invention
The technical scheme is that and provide a kind of pharmaceutical composition treating mastofibroma, present invention also offers
The preparation method of this pharmaceutical composition and purposes.
The present invention relates to a kind of pharmaceutical composition treating mastofibroma, it is by the crude drug system of following weight proportioning
Standby preparation:
Radix Salviae Miltiorrhizae 15~18 parts, Radix Angelicae Sinensis 12~15 parts, Radix Scrophulariae 15~18 parts, Spica Prunellae 12~15 parts, Fructus Forsythiae 12~15 parts, Fructus Persicae
Core 10~12 parts, Flos Carthami 6~9 parts, Rhizoma Chuanxiong 4~6 parts, Rhizoma Bolbostematis 10~12 parts, Concha Ostreae 25~30 parts, Rhizoma Cyperi 8~10 parts, strongly fragrant
Gold 8~10 parts, Radix Bupleuri 8~10 parts, the Radix Paeoniae Alba 8~10 parts, Radix Platycodonis 4~6, Radix Achyranthis Bidentatae 8~10 parts, Radix Glycyrrhizae 4~6 parts.
Further, it is the preparation being prepared from by the crude drug of following weight proportioning:
Radix Salviae Miltiorrhizae 15 parts, Radix Angelicae Sinensis 12 parts, Radix Scrophulariae 18 parts, Spica Prunellae 15 parts, Fructus Forsythiae 15 parts, 12 parts of Semen Persicae, 9 parts of Flos Carthami, Rhizoma Chuanxiong 6
Part, Rhizoma Bolbostematis 12 parts, Concha Ostreae 30 parts, Rhizoma Cyperi 10 parts, Radix Curcumae 10 parts, Radix Bupleuri 10 parts, the Radix Paeoniae Alba 10 parts, Radix Platycodonis 6, Radix Achyranthis Bidentatae 10 parts,
6 parts of Radix Glycyrrhizae.
Wherein, it is that the water of the primary crude drug powder by described crude drug or crude drug is or/and extractive with organic solvent is alive
Property composition, adds that pharmaceutically acceptable adjuvant or complementary composition are prepared as the preparation pharmaceutically commonly used.
Further, described preparation is oral formulations.
Further, described preparation is tablet, capsule, soft capsule, granule, pill, drop pill, is administered orally
Liquid, sub-lingual spray, injection.
The present invention also provides for giving a kind of method preparing above-mentioned compositions, and it comprises the steps:
A, weigh the crude drug of weight proportion;
The water of b, the primary crude drug powder of each crude drug or crude drug, or/and extractive with organic solvent is active component, adds
Pharmaceutically acceptable adjuvant or complementary composition are prepared as the preparation pharmaceutically commonly used.
Further, the organic solvent described in b step is 60-95%v/v ethanol.
Present invention also offers aforementioned pharmaceutical compositions purposes in the medicine of preparation treatment mastofibroma.
Have been accepted as " organic conception ", " determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs " at present, " compound recipe use ", " compound compatibility medication is such as used military forces " are the traditional Chinese medical science
Most scientific maximally effective several big advantages, wherein " compound compatibility medication is such as used military forces " is the original theory of Chinese medicine of very science.In
Each medicine tight compatibility all linked with one another as arrayed troops for battle in doctor's prescription, is that it is better than the effective means of Western medicine formula.The traditional Chinese medical science
Prescription theory is thought, each prescription, not only needs to select the appropriate compatibility of suitable medicine according to etiology and pathogenesis, also should meet simultaneously
The prescription compatibility theory of the basic structure of prescription, i.e. " monarch, minister, help, make ", the prescription compatibility of so-called " monarch, minister, help, make ", it is simply that
It sets up the scientific matching on the comprehensive judgement basis to disease pathogenesis.In medical side by too many levels, Mutiple Targets integrate
The biological mechanism of regulation, heavy serious disease this to coronary heart disease recuperate under medical treatment, can obtain than Western medicine more preferably, more green natural without
The therapeutic effect of toxic and side effects, and this curative effect is built upon on the accurate instruction of the above-mentioned traditional Chinese medical science original theory of tradition, this
Invention prescription just have followed this principle.
In pharmaceutical composition of the present invention, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Radix Scrophulariae, Radix Paeoniae Alba nourshing blood and promoting blood circulation, as a means of moistening foster " woman is congenital " (liver)
Source, and so blood circulation promoting and blood stasis dispelling and taste Tianjin of nourishing blood, can anti-purification stagnation resolvation painful abdominal mass and just hinder, therefore with Radix Salviae Miltiorrhizae as monarch (medicine), GUISHAO Radix Scrophulariae
For left hall ministerial drug, carry on a shoulder pole this main task.Semen Persicae, Flos Carthami, Rhizoma Chuanxiong, Radix Achyranthis Bidentatae blood circulation and removing stasis, can assist monarch drug potentiation, therefore send as right hall
Ministerial drug.Breast breast is by the meridians compress of liver, qi as the commander of blood again, gas row then blood, and blood is not brought about the desired sensation to push away and do not lived, and gas must not moisten not by blood
OK, Rhizoma Chuanxiong is blood system gas medicine, and Rhizoma Cyperi, Radix Curcumae, Radix Bupleuri are good at and regulate the flow of vital energy soothing the liver, and the Radix Paeoniae Alba is good at easing the affected liver, can assist a ruler in governing a country the present invention and not only have
The merit of vital energy regualting and blood circulation-promoting, and have conditioning Liver Channel effect, therefore can be used as the adjuvant drug of left.The kind treatment breast Rhizoma Bolbostematis of disease, Spica Prunellae are longer than
Removing summer-heat softening the hard mass digestion sucutaneous nodule, joins the Concha Ostreae of hard masses softening and resolving, the Fructus Forsythiae of dispersing swelling and dissipating binds, eliminating stagnation disappear the Radix Scrophulariae of scrofula, and effect more writes, in
It is with the adjuvant drug for right wing, right hall ministerial drug Semen Persicae, Flos Carthami, Rhizoma Chuanxiong, the thin knot of Radix Achyranthis Bidentatae repercussive can be assisted a ruler in governing a country, make nodule in the breast to dissipate.Radix Platycodonis
Property upwards, can draw each medicine up reach in breast breast;Radix Achyranthis Bidentatae is by evil blood, and property is downward, and the heresy that can draw stasis is descending and tonneau breast network;Radix Glycyrrhizae
Medicine all with middle coordination;Therefore all negative mission making medicine of Radix Platycodonis, Radix Achyranthis Bidentatae, Radix Glycyrrhizae.So match, not only can the stasis of blood of promoting the circulation of blood stagnant, dissipate expectorant it
Condense, the strongly fragrant addiction can vented one's spleen again, invigorate blood circulation and do not consume liver blood, the stasis of blood can also tissue regeneration promoting, fullness and oppression sensation in the epigastrium due to accumulation of phlegm go and breast network lead to, liver blood must moisten and nodules of the breast
Must dissipate, nodule in the breast can be made to remove, breast is pacified again.
Below respectively group flavour of a drug post is clearly demarcated, complements each other, has given full play to the exclusive compound compatibility medication of Chinese medicine such as
Row army structure the formation as sexology research methodology marrow of analyzing mentally, have good therapeutic effect for mastofibroma, can be effectively
Alleviate its symptom, provide a kind of new selection for clinical application.
Detailed description of the invention
The preparation of embodiment 1 medicine of the present invention
Take Radix Salviae Miltiorrhizae 15 grams, Radix Angelicae Sinensis 12 grams, Radix Scrophulariae 18 grams, Fructus Forsythiae 15 grams, Spica Prunellae 15 grams, 12 grams of Semen Persicae, 9 grams of Flos Carthami, river
Rhizome of chuanxiong 6 grams, Rhizoma Bolbostematis 12 grams, Concha Ostreae 30 grams, Rhizoma Cyperi 10 grams, Radix Curcumae 10 grams, Radix Bupleuri 10 grams, the Radix Paeoniae Alba 10 grams, Radix Platycodonis 6, Radix Achyranthis Bidentatae 10
Gram, 6 grams of Radix Glycyrrhizae.Each flavour of a drug weigh according to quantity, and Concha Ostreae is smashed to pieces, and Radix Curcumae, Rhizoma Bolbostematis are smashed up, and add enough water purification and are decocted first this three medicine, boiling
After again slow fire decoct more than half an hour, then remaining each medicine lower, decoct about 12 minutes to 15 minutes again after boiling, collect decocting liquid;Medicinal residues
Add water decoction 2 times, merge each decocting liquid, obtain decoction.
The preparation of embodiment 2 pharmaceutical composition of the present invention
Take Radix Salviae Miltiorrhizae 18 grams, Radix Angelicae Sinensis 15 grams, Radix Scrophulariae 15 grams, Fructus Forsythiae 12 grams, Spica Prunellae 12 grams, 10 grams of Semen Persicae, 6 grams of Flos Carthami, river
Rhizome of chuanxiong 4 grams, Rhizoma Bolbostematis 10 grams, Concha Ostreae 25 grams, Rhizoma Cyperi 8 grams, Radix Curcumae 8 grams, Radix Bupleuri 8 grams, the Radix Paeoniae Alba 8 grams, Radix Platycodonis 4, Radix Achyranthis Bidentatae 8 grams, sweet
Grass 4 grams.After first with 70%v/v ethanol extraction 2 times, merging alcohol extract, medicinal residues with soak by water 2 times, merge decocting liquid again.Respectively will
After alcohol extract, decocting liquid concentrate, mixing, add suitable dextrin, soluble starch, pelletize, obtain granule.
The preparation of embodiment 3 pharmaceutical composition of the present invention
Take Radix Salviae Miltiorrhizae 16 grams, Radix Angelicae Sinensis 14 grams, Radix Scrophulariae 16 grams, Fructus Forsythiae 13 grams, Spica Prunellae 13 grams, 11 grams of Semen Persicae, 8 grams of Flos Carthami, river
Rhizome of chuanxiong 5 grams, Rhizoma Bolbostematis 11 grams, Concha Ostreae 28 grams, Rhizoma Cyperi 9 grams, Radix Curcumae 9 grams, Radix Bupleuri 9 grams, the Radix Paeoniae Alba 9 grams, Radix Platycodonis 5, Radix Achyranthis Bidentatae 9 grams, sweet
Grass 5 grams.After first with 50-60%v/v ethanol extraction 3 times, merge alcohol extract, reclaim ethanol, add suitable dextrin, solubility shallow lake
Powder, pelletizes, and tabletting obtains tablet.
The preparation of embodiment 4 pharmaceutical composition of the present invention
The granule of Example 2 preparation, fills capsule, obtains capsule.
The preparation of embodiment 5 pharmaceutical composition of the present invention
Take Radix Salviae Miltiorrhizae 15 grams, Radix Angelicae Sinensis 12 grams, Radix Scrophulariae 18 grams, Fructus Forsythiae 15 grams, Spica Prunellae 15 grams, 12 grams of Semen Persicae, 9 grams of Flos Carthami, river
Rhizome of chuanxiong 6 grams, Rhizoma Bolbostematis 12 grams, Concha Ostreae 30 grams, Rhizoma Cyperi 10 grams, Radix Curcumae 10 grams, Radix Bupleuri 10 grams, the Radix Paeoniae Alba 10 grams, Radix Platycodonis 6, Radix Achyranthis Bidentatae 10
Gram, 6 grams of Radix Glycyrrhizae.After first with 95%v/v ethanol extraction 2 times, merging alcohol extract, medicinal residues with soak by water 2 times, merge decocting liquid again.Point
After alcohol extract, decocting liquid not being concentrated, mixing, stand, filter, filtrate adds appropriate correctives and antibacterial, is prepared as being administered orally
Liquid.
The preparation of embodiment 6 pharmaceutical composition of the present invention
The decoction of Example 1 preparation, stands, takes supernatant, after concentration, dry, pulverize, standby;Take appropriate poly-second two
Alcohol 4000, after melting, adds above-mentioned medicated powder in melted substrate, is incubated at 75-85 DEG C;Use various pill dripping machine, drip inside/outside
Footpath and a speed appropriateness, instilled in dimethicone, collect drop pill, obtain drop pill.
Beneficial effects of the present invention is proved below by way of pharmacodynamics test.
Clinic (outpatient service) the treatment situation of test example medicine of the present invention
(1) patient profiles is accepted for medical treatment
According to inventor's clinical practice of more than 30 year, with Drug therapy mammary gland fibroadenoma patient 15 example of embodiment 1, obtain
Obtained more satisfied curative effect.Treatment time: according to the concrete conditions such as each conditions of patients weight, age size, physical strength it
Different and difference, typically can alleviate at two or three week, 3 weeks~about 12 months symptoms, sign, health check-up can recover normal or
Normal.Mammary gland fibroadenoma is apt to occur in 18 to 25 years old sexual function female breast in vigorous period outside upper quadrant (other age brackets
Women also can occur), in addition to there is lump, patient is generally without obvious subjective symptoms.Adenoma is often single-shot, also has many originator.Gland
Tumor is rounded or oval, and diameter is the most common with 1~3 centimetre of person, also has smaller or greater person, even visible huge person.Its matter
Ground is tough and tensile, clear border, and smooth surface is movable good, and with skin and surrounding tissue without adhesion, mobility is big, and that touches has slip
Sense, axillary lymph is tied without enlargement.Adenoma is many without pain, and also without tenderness, only 14% has mild pain, in paroxysm or accidental or menstruation
Shi Jifa.The usual poor growth of lump, can the several years unchanged, but can increase rapidly at edge design, individual other can be in this
Shi Fasheng sarcomatous change, but its size character does not typically change with menstrual cycle.Only a few patient's nipple has limpid discharge, accounts for
0.75%。
(2) treatment standard
Recovery from illness: symptom, sign disappear (mammary gland fibroadenoma i.e. lump in breast and pain are wholly absent).
Evident in efficacy: symptom, sign substantially alleviate (mammary gland fibroadenoma i.e. lump volume-diminished more than half, have slight
Tenderness, after premenstrual, angry and fatigue, the degree of mastalgia substantially alleviates before relatively treating).
There is certain effect: patients symptomatic, sign are slightly alleviated, and (mammary gland fibroadenoma i.e. lump quality deliquescing, volume contracts
Little not enough half, after premenstrual, angry and fatigue, mastalgia has alleviated).
Invalid: symptom etc. all remain unchanged, do not improve completely.
(3) Therapeutic Method
1, the made decoction of embodiment 1, every bu takes for 3 times, and serveing on 10 is a course for the treatment of, can drug withdrawal between the course for the treatment of and the course for the treatment of
1, also answer drug withdrawal if suffering from other new diseases such as diarrhoea grade.
2, note and science nurse one's health daily life, in accordance with the points for attention of some necessity, such as:
(1) keep good phychology and healthy life, learning style.Overcome bad dietary habit and hobby, regular
Ground work, study.Note the stable of emotion with and happy, be sure not excitement, get angry, depressed, worried, the stasis increasing the weight of Liver Channel is newborn with breast
The irregular operating (" the stagnation of QI then expectorant blood coagulation stasis of blood " " alluvial then becomes knot ") of tissue.Emotional lability can suppress the ovulation function of ovary,
Occur that progesterone reduces, make estrogen relatively increase, cause primary disease.
(2) avoid using the facial cream containing estrogen and medicine.Some women are contained female for beautifying skin, life-time service
The facial cream of hormone, long can induce primary disease.
(3) want in good time marriage and childbirth.Although encouraging late marriage and late childbirth, but should not be the slowest.Women marries for best 25 years old to 28 years old, and 30
Before year, fertility, gives birth to the most unfavorable aristogenesis too late.Secondly, it should be noted that contraception, because when conceived 6 weeks, embryo villi secretion female sharp
Element and progestogen can stimulate mammary gland;If making artificial abortion, the mammary gland tissue of hypertrophy is difficult to atrophy, it more difficult to restore to the original state, abnormal breast
Gland is easily fallen ill.
(4) sexual life wants appropriate and regular.Women is said by breast, is not only suckling organ, is also sexual organ simultaneously.Property raw
When living, breast can generating period change.Gestation, suckling are a kind of physiological regulation, therefore, in good time marriage and childbirth, the food in one's mouth to mammary gland function
Breast, is favourable to mammary gland;On the contrary, if more than 30 years old unmarried, do not educate or women that suckling is few, the most ill.
(5) cherish breast, frequent health check-up.The women of each different age group should adhere to Condition of Breast Self-examination, and menstruation monthly is done
Carry out after Jing;The women of more than 30 years old arrives mammary gland training every year and carries out a health check-up, and the women of more than 40 years old asks training every half a year
Doctor's health check-up once, is accomplished early to find early treatment.
(3) adopt a correct attitude towards mastopathy, can not hide one's sickness for fear for the treatment of.Find that breast to be sought medical advice after having lump immediately, partner treatment.
Although mammary gland fibroma is benign tumor, but tumor body between the possibility cancerated, particularly edge design is also had to increase quickly or year
Age is bigger than normal, and the course of disease is longer, or with cyclomastopathy or multiple relapse person, more should enhance your vigilance, go to a doctor in time, prevents the state of an illness from becoming
Change.Feminine half should accomplish early to prevent early to find early treatment, the udder health of special concern oneself.
(4) therapeutic outcome
With medicine composite for curing mammary gland fibroadenoma patient 15 example of the present invention between thirties years, it is thus achieved that preferably treat
Effect, nurses one's health daily life by above-mentioned science, sincerely abides by points for attention, can obtain good result.
By above-mentioned treatment standard, in 15 example patients, having 8 example recoveries from illness, cure rate reaches 53.33%;4 examples are evident in efficacy, reach
26.67%;1 example has certain effect, accounts for 6.67%;2 example DeGrains (invalid), account for 13.33%.Total effective rate reaches 86.67%.
Model case
Patient, female, 20 years old, tall, body is healthy and strong.Patient finds that unintentionally the outside upper quadrant of oneself right breast has multiple
The hard lump of Semen Glycines size, but not pain, through looking into, examine as mammary gland fibroadenoma.After the moon in ten days, patient seeks tcm diagnosis and treatment.
Its outside upper quadrant of right breast about more than 10 tumor mass, in oval ball-type or ball-shaped, oncontacting is keenly felt, and that lays one's hand on is strong but pliable in texture, smooth surface, lives
Dynamic good, clear border, there are slip sense, axillary lymph knot to have no enlargement.Except this, remaining without other symptoms, tongue arteries and veins is also normal, only chi
The most weak.Already clarify a diagnosis, i.e. give pharmaceutical composition of the present invention (prepared by embodiment 1), advise between new stadium such as its menstrual period, diseases caused by exogenous pathogenic factor etc.
Temporarily withdraw, and sternly abide by the method for administration of above-mentioned " Therapeutic Method " it " 1 " and the science conditioning of " 2 " and points for attention.Patient abides by
Advising, adhere to nearly October of taking medicine, unexpectedly make tumor mass gradually soften, dissipate, symptom, sign are all reformed often.Hereafter, annual health check-up, so far
Have no recurrence.
In sum, drug regimen composition formula of the present invention is precise and appropriate, and (or it is sick to alleviate it effectively to treat mammary gland fibroadenoma
Condition), and avoid the toxic and side effects that chemical drugs is had, provide a kind of new selection for clinical application.
Claims (8)
1. the pharmaceutical composition treating mammary gland fibroma, it is characterised in that: it is by the crude drug system of following weight proportioning
Standby preparation:
Radix Salviae Miltiorrhizae 15 parts, Radix Angelicae Sinensis 12 parts, Radix Scrophulariae 18 parts, Spica Prunellae 15 parts, Fructus Forsythiae 15 parts, 12 parts of Semen Persicae, 9 parts of Flos Carthami, Rhizoma Chuanxiong 6 parts,
Rhizoma Bolbostematis 12 parts, Concha Ostreae 30 parts, Rhizoma Cyperi 10 parts, Radix Curcumae 10 parts, Radix Bupleuri 10 parts, the Radix Paeoniae Alba 10 parts, Radix Platycodonis 6, Radix Achyranthis Bidentatae 10 parts, Radix Glycyrrhizae
6 parts.
Pharmaceutical composition the most according to claim 1, it is characterised in that: it be by the primary crude drug powder of described crude drug,
Or the water of crude drug is or/and extractive with organic solvent is active component, adds pharmaceutically acceptable adjuvant or complementary composition
It is prepared as the preparation pharmaceutically commonly used.
Pharmaceutical composition the most according to claim 1 and 2, it is characterised in that: described preparation is oral formulations.
Pharmaceutical composition the most according to claim 3, it is characterised in that: described preparation is tablet, capsule, granule
Agent, pill, drop pill or oral liquid.
Pharmaceutical composition the most according to claim 4, it is characterised in that: described capsule is soft capsule.
6. prepare the method for pharmaceutical composition described in claim 1-5 any one for one kind, it is characterised in that: it includes walking as follows
Rapid:
A, weigh the crude drug of weight proportion;
The water of b, the primary crude drug powder of each crude drug or crude drug, or/and extractive with organic solvent is active component, adds pharmacy
Upper acceptable adjuvant or complementary composition are prepared as the preparation pharmaceutically commonly used.
Preparation method the most according to claim 6, it is characterised in that: the organic solvent described in b step is 60-95%v/v
Ethanol.
8. the purposes in the medicine of preparation treatment mastofibroma of the pharmaceutical composition described in claim 1-5 any one.
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