CN102813746B - Traditional Chinese medicine composition for treating numbness of fingers - Google Patents

Traditional Chinese medicine composition for treating numbness of fingers Download PDF

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CN102813746B
CN102813746B CN201210270757.3A CN201210270757A CN102813746B CN 102813746 B CN102813746 B CN 102813746B CN 201210270757 A CN201210270757 A CN 201210270757A CN 102813746 B CN102813746 B CN 102813746B
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chinese medicine
medicine composition
fingers
radix
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CN102813746A (en
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邱相君
王淑英
王建刚
李艳
杜景霞
李瑞芳
段冷昕
杨晖
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Henan University of Science and Technology
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Henan University of Science and Technology
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Abstract

The invention discloses a traditional Chinese medicine composition for treating numbness of fingers. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine materials by weight: 5-15 parts of radix bupleuri, 2-5 parts of rattletop, 10-20 parts of radix paeoniae alba, 5-15 parts of radix achyranthis bidentatae, 5-15 parts of cassia twig, 5-15 parts of medlar, 3-6 parts of schisandra chinensis and 5-10 parts of liquorice. By adopting radix achyranthis bidentatae and schisandra chinensis in the formula of the traditional Chinese medicine composition provided by the invention, the symptoms of numbness and gall of fingers are improved from peripheral and central nerve system, and by matching with the tonifying components of medlar and liquorice, the purposes of comprehensively conditioning as well as treating both symptoms and root causes are achieved. The traditional Chinese medicine composition has the advantages of reasonable formula, accurate curative effect and higher safety, and the materials in the formula have wide resource and low cost.

Description

A kind of Chinese medicine composition that is used for the treatment of numbness of the fingers
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition that is used for the treatment of numbness of the fingers.
Background technology
Numbness of the fingers belongs to the arthromyodynia category of the traditional Chinese medical science, and so-called arthromyodynia refers to suffer after the invasion and attack of wind, cold, wet exopathogen when human body flesh table meridians, makes QI-blood circulation freely not cause the disease of muscle, finger-joint numbness, joint stuffiness, arthroncus, local pain.Doctor trained in Western medicine thinks that numbness of the fingers is limb motion neuronal damage, the capillary vessel of Motor nerve fibre periphery is blocked, and microcirculation is obstructed, compressing motor fiber, cause motor neuron, nerve fiber to be badly damaged, neural conducting power and conduction velocity decline and cause.Numbness of the fingers is due to paralysis due to windstroke, diabetes mostly, neuritis and cervical spondylosis, and rheumatism, rheumatoid, vasculitis, lumbar spondylosis etc. cause.
At present, be used for the treatment of the medicine of numbness of the fingers taking blood circulation promoting and blood stasis dispelling, trophic nerve as main, as used notoginseng preparations, intravenous injection vitamin B1 and B12 etc., but therapeutic effect is not good.It is more that Chinese medicine is used for the treatment of the formula of numb hand and foot, Chinese medicine greatly mainly with Radix Paeoniae, Rhizoma Chuanxiong, Flos Chrysanthemi etc. except wind medicine be mainly to fill a prescription.China invention " a kind of Chinese medicine composition for the treatment of numbness of the fingers " publication number is CN102293918A(date of publication: 2011.12.28) disclosed formula is aided with the multiple blood yiqi components such as Radix Ginseng, the Radix Astragali, Fructus Jujubae in patent application, and it is imprecise for the therapeutic effect of the symptoms such as numbness, swelling and the pain of finger to overemphasize blood yiqi.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition that is used for the treatment of numbness of the fingers.
The technical solution adopted in the present invention is as follows: described Chinese medicine composition is made up of the raw material of Chinese medicine of following portions by weight: 5~15 parts of Radix Bupleuri, 2~5 parts of Rhizoma Cimicifugaes, 10~20 parts of the Radix Paeoniae Albas, 5~15 parts of Radix Achyranthis Bidentataes, 5~15 parts of Ramulus Cinnamomi, 5~15 parts of Fructus Lycii, 3~6 parts of Fructus Schisandrae Chinensis, 5~10 parts, Radix Glycyrrhizae.
Optimal technical scheme of the present invention is: described Chinese medicine composition is made up of the raw material of Chinese medicine of following portions by weight: 10 parts of Radix Bupleuri, 4 parts of Rhizoma Cimicifugaes, 12 parts of the Radix Paeoniae Albas, 10 parts of Radix Achyranthis Bidentataes, 10 parts of Ramulus Cinnamomi, 10 parts of Fructus Lycii, 5 parts of Fructus Schisandrae Chinensis, 6 parts, Radix Glycyrrhizae.
Powder, capsule, decoction, pill, tablet or granule that the dosage form of above-mentioned Chinese medicine composition can be made according to 2010 editions requirements of Chinese Pharmacopoeia, be preferably decoction or pill.
When preparation, get each component raw material of Chinese medicine by formulation weight umber, be crushed to 120 order fine powders, make powder or encapsulated; Maybe by the powder after sieving in 100 DEG C of sterilization treatment 30 minutes, add refined honey 30g by every 100g powder, be heated to 70 DEG C and mix with certain amount of boiling water, after refine 3 times, make the honeyed pill of every heavily about 0.3g, 60 DEG C of honeyed pill are dry.
Radix Achyranthis Bidentatae, Fructus Schisandrae Chinensis and Radix Glycyrrhizae in formula all has effect of anti-inflammatory and antalgic, dredging collateral, can effectively improve numbness of the fingers, distending pain symptom.Wherein, Radix Achyranthis Bidentatae hardship is let out, is declined, and is good at tonneau, can promoting blood circulation, by blood addiction, sharp joint, relaxing muscles and tendons network, again can conducting blood to flow downwards, and can bone and muscle strengthening, strong waist knee joint, Radix Achyranthis Bidentatae can draw the through sick institute of all medicines, improve local blood for and reducing swelling and alleviating pain.Fructus Schisandrae Chinensis is obvious to the pharmacological action of central nervous system aspect, has Central Analgesic Effect, can improve the threshold of pain, and the effect such as tranquillizing and allaying excitement, convulsion.Other component temperature as pungent in Ramulus Cinnamomi, kind cold-dispelling, being equipped with the Radix Paeoniae Alba has and coordinates that battalion defends, the effect of dredge the meridian passage, and Rhizoma Cimicifugae draws clearing heat in QI system and rises, and can strengthen dispersing ailment said due to cold or exposure.
Clinical test results is as follows:
(1), physical data
All numbness of the fingers MethodsThe cases enrolled are the abnormal or moderate patients with abnormal of doigte, get rid of joint severe deformity patient, have serious gastroduodenal ulcer history patient and have the organ disease patients such as serious brain Liver and kidney.Selected 90 examples altogether, wherein male 41 examples, female's 49 examples, age 40-65 year, the numbness of the fingers course of disease is all greater than 6 months.In 90 routine MethodsThe cases enrolled, the numbness of the fingers wherein being caused by medicine (chemotherapeutic is as vinca medicine, cisplatin) is 25 examples, and what diabetes caused is 20 examples, and what rheumatism caused is 15 examples, 17 examples that cervical spondylosis causes, 13 examples that unknown cause causes.
(2), research method
The selected patient of 90 example is divided into two groups, treatment group 47 examples, matched group 43 examples.
Treatment group is taken in Chinese medicine composition of the present invention proportioning described in embodiment 1, a twice-daily, every day potion, one after each meal.
Matched group gives medicine trophic nerve: once-a-day intramuscular injection VB11 00mg+B120.5-1mg, and medicine blood circulation promoting and blood stasis dispelling, three times on the one oral XUESAITONG PIAN 100mg.
Two groups can be continued to control blood glucose treatment, cervical vertebra physiotherapy during treating, but the vinca of stopping using etc. may damage the medicine of peripheral neuritis, within 15 days, are 1 course for the treatment of.
(3), curative effect determinate standard
Cure: numbness of the fingers disappears, finger-joint is movable convenient; Effective: numbness of the fingers obviously alleviates, there is slight paraesthesia, do not affect finger-joint activity; Effective: numbness of the fingers symptom is improved, and doigte is extremely still more obvious, affects finger-joint activity; Invalid: numbness of the fingers is without improvement, and doigte can not tolerate extremely.
(4), result of study
Treat after 30 days two groups of curative effect comparisons:
Figure GDA0000451478870000031
(5), conclusion
Treat after 30 days, treatment group is 94% to the total effective rate of numbness of the fingers, is significantly higher than the 77%(P<0.01 of matched group).
Take Chinese medicine composition of the present invention and do not occur the untoward reaction such as hepatic and renal function injure, show that Chinese medicine composition of the present invention has good safety.
The formula of the treatment numbness of the fingers Chinese medicine composition the present invention relates to rationally, determined curative effect, the raw material of Chinese medicine wide material sources that use in formula, with low cost, take while being formulated as honeyed pill with easy to carry.The Radix Achyranthis Bidentatae using in formula and Fructus Schisandrae Chinensis respectively from periphery and maincenter improve numbness of the fingers, the symptom that swells and ache, compatible with Fructus Lycii, Radix Glycyrrhizae tonification composition, play the object of comprehensively regulating, treating both the principal and secondary aspects of a disease.
Detailed description of the invention
Embodiment 1
Chinese medicine composition of the present invention is made up of the raw material of Chinese medicine of following portions by weight: 10 grams of Radix Bupleuri, 4 grams of Rhizoma Cimicifugaes, 12 grams of the Radix Paeoniae Albas, 10 grams of Radix Achyranthis Bidentataes, 10 grams of Ramulus Cinnamomi, 10 grams of Fructus Lycii, 5 grams of Fructus Schisandrae Chinensis, 6 grams, Radix Glycyrrhizae.Preparation method is: get each tcm components raw material by above-mentioned parts by weight, be crushed to 120 order fine powders, by the powder after sieving in 100 DEG C of sterilization treatment 30 minutes, add refined honey 30g by every 100g powder, being heated to 70 DEG C mixes with certain amount of boiling water, after refine 3 times, make the honeyed pill of every heavily about 0.3g, 60 DEG C of honeyed pill are dry.
Embodiment 2
Chinese medicine composition of the present invention is made up of the raw material of Chinese medicine of following portions by weight: 12 grams of Radix Bupleuri, 5 grams of Rhizoma Cimicifugaes, 20 grams of the Radix Paeoniae Albas, 5 grams of Radix Achyranthis Bidentataes, 13 grams of Ramulus Cinnamomi, 8 grams of Fructus Lycii, 3 grams of Fructus Schisandrae Chinensis, 10 grams, Radix Glycyrrhizae.Preparation method is: get each tcm components raw material by above-mentioned parts by weight, be crushed to fine powder, packing capsulae vacuus into is capsule.
Embodiment 3
Chinese medicine composition of the present invention is made up of the raw material of Chinese medicine of following portions by weight: 15 grams of Radix Bupleuri, 2 grams of Rhizoma Cimicifugaes, 15 grams of the Radix Paeoniae Albas, 8 grams of Radix Achyranthis Bidentataes, 10 grams of Ramulus Cinnamomi, 15 grams of Fructus Lycii, 5 grams of Fructus Schisandrae Chinensis, 7 grams, Radix Glycyrrhizae.Preparation method is: get each tcm components raw material by above-mentioned parts by weight, be crushed to fine powder, make powder.
Embodiment 4
Chinese medicine composition of the present invention is made up of the raw material of Chinese medicine of following portions by weight: 5 grams of Radix Bupleuri, 5 grams of Rhizoma Cimicifugaes, 16 grams of the Radix Paeoniae Albas, 15 grams of Radix Achyranthis Bidentataes, 12 grams of Ramulus Cinnamomi, 5 grams of Fructus Lycii, 4 grams of Fructus Schisandrae Chinensis, 5 grams, Radix Glycyrrhizae.Preparation method is: get after each tcm components raw material adds decocting and obtain the about 300ml of medicinal liquid by above-mentioned parts by weight, make decoction.
Embodiment 5
Chinese medicine composition of the present invention is made up of the raw material of Chinese medicine of following portions by weight: 15 grams of Radix Bupleuri, 3 grams of Rhizoma Cimicifugaes, 18 grams of the Radix Paeoniae Albas, 12 grams of Radix Achyranthis Bidentataes, 7 grams of Ramulus Cinnamomi, 12 grams of Fructus Lycii, 5 grams of Fructus Schisandrae Chinensis, 8 grams, Radix Glycyrrhizae.Preparation method is: get each tcm components raw material by above-mentioned parts by weight, crushing fine powder, adds adjuvant to make tablet.
Embodiment 6
Chinese medicine composition of the present invention is made up of the raw material of Chinese medicine of following portions by weight: 8 grams of Radix Bupleuri, 5 grams of Rhizoma Cimicifugaes, 20 grams of the Radix Paeoniae Albas, 10 grams of Radix Achyranthis Bidentataes, 15 grams of Ramulus Cinnamomi, 10 grams of Fructus Lycii, 6 grams of Fructus Schisandrae Chinensis, 10 grams, Radix Glycyrrhizae.Preparation method is: get each tcm components raw material by above-mentioned parts by weight, be crushed to 120 order fine powders, add ethanol to make adhesive after mix homogeneously, add starch to make filler, be pressed into granule.
Model case 1: Luoyang, henan city Mr. Zhao, 55 years old, suffer from cervical spondylosis for many years, adhere to cervical vertebra holder treatment, but that finger occurs is numb, swell and ache etc., paraesthesia reaches more than 1 year, takes the Chinese medicine activating blood and resolving stasis and treatings such as notoginseng preparations invalid, in adhering to cervical vertebra holder physical therapy, 2 times on the one, one time 8 take honeyed pill of the present invention after 15 days, numbness of the fingers symptom is improved, and takes after 30 days that numbness of the fingers disappears, finger-joint is movable convenient.
Model case 2: Xinan County, Henan Mrs Liu, 46 years old, patient's unknown cause caused two numbness of the fingers more than 1 year, the slight swelling of finger-joint in the recent period, hands are met the cold and hot twinge of feeling, night, distending pain sense was obvious, repeatedly through treatment weak curative effects such as acupuncture-moxibustion, Chinese medicine blood circulation promoting and blood stasis dispelling, vitamin B12 intramuscular injection, 2 times on the one, one time 8 take honeyed pill of the present invention after 30 days, numbness of the fingers symptom is improved, and finger-joint swelling takes a turn for the better, and meets hot and cold water sensation of pricking and disappears.

Claims (2)

1. be used for the treatment of a Chinese medicine composition for numbness of the fingers, it is characterized in that this Chinese medicine composition is made up of the raw material of Chinese medicine of following portions by weight: 5~15 parts of Radix Bupleuri, 2~5 parts of Rhizoma Cimicifugaes, 10~20 parts of the Radix Paeoniae Albas, 5~15 parts of Radix Achyranthis Bidentataes, 5~15 parts of Ramulus Cinnamomi, 5~15 parts of Fructus Lycii, 3~6 parts of Fructus Schisandrae Chinensis, 5~10 parts, Radix Glycyrrhizae.
2. according to a kind of Chinese medicine composition that is used for the treatment of numbness of the fingers claimed in claim 1, it is characterized in that the weight composition umber of described Chinese medicine composition is as follows: 5~10 parts of Radix Bupleuri, 3~5 parts of Rhizoma Cimicifugaes, 10~15 parts of the Radix Paeoniae Albas, 10~15 parts of Radix Achyranthis Bidentataes, 8~12 parts of Ramulus Cinnamomi, 10~15 parts of Fructus Lycii, 3~5 parts of Fructus Schisandrae Chinensis, 5~8 parts, Radix Glycyrrhizae.
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CN103566044A (en) * 2013-10-25 2014-02-12 安徽工贸职业技术学院 Traditional Chinese medicinal composition for activating blood circulation to relieve pain
CN103566224A (en) * 2013-10-25 2014-02-12 安徽工贸职业技术学院 Traditional Chinese medicine composition for treating numbness of limbs

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CN1115663C (en) * 1997-11-22 2003-07-23 皇家菲利浦电子有限公司 Audio processing arrangement with multiple sources

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