CN1115663A - Medicine for curing hypertension - Google Patents
Medicine for curing hypertension Download PDFInfo
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- CN1115663A CN1115663A CN 95103456 CN95103456A CN1115663A CN 1115663 A CN1115663 A CN 1115663A CN 95103456 CN95103456 CN 95103456 CN 95103456 A CN95103456 A CN 95103456A CN 1115663 A CN1115663 A CN 1115663A
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Abstract
The medicine for hypertension is prepared with the material of Radix paeoniae alba, licorice root, cassia twig, kudzu vine root, schisandra and Achyranthes bidentata. After desiccation and grinding into 10-32 mesh powder, the medicine is packed into tea bag of filter paper.
Description
The present invention relates to a kind of medicine for the treatment of hypertension, specifically is the Chinese patent medicine of feedstock production with the Chinese herbal medicine.
Hypertension is the common frdquently encountered disease of serious harm human health, and according to World Health Organization's report, it is 9.1% that the hypertension patient that is grown up more than 20 years old leads.
Hypertension itself is a kind of important diseases of harm humans health, it still is one of main hazard factor of apoplexy and coronary heart disease, hypertension can be in no clinical symptoms or only higher but when not reaching the clinical diagnosis standard, evidence of coronary heart diseases is increased at double.
Both at home and abroad to the primary disease Drug therapy, run into following thorny problem at present:
1, the diuretic antihypertensive medicine is for a long time with producing hypokalemia, hyponatremia, hyperuricemia, hyperlipemia and hyperglycemia, hypochloraemia and bringing out renal calculus.
2, the noradrenergic nerve guiding drug plays drowsiness, headache, spirit depressing, hypotension, sexual impotence and toxic hepatitis.
3, α-blocker causes giddy, dizzy, unable, peripheral edema and weight increase.
4, vasodilation causes cardiopalmus, flush, headache, dizziness, feels sick, increases the weight of cardiac-cerebral ischemia, brings out angina pectoris.
5, calcium antagonist is not obvious to the diastolic hypertension effect.
6, converting enzyme inhibitor can cause Toxicity of Kidney in a large number, bone marrow depression, erythra, dysgeusia, symptomatic hypotension.
Though also there are some to treat hypertensive Chinese patent medicine, because effect is very not remarkable, the patient still has to depend on some Western medicine, as " nifedipine ", " nimodipine ", " indapamide ".And usually Chinese patent medicine to take cost for a long time higher, be not suitable for the hyperpietic and use.
The object of the present invention is to provide a kind of Peripheral resistance of reducing that has, microcirculation improvement reduces hypertension, especially crosses high diastolic blood pressure, increases the vitals blood supply, reduces, alleviates the hypertension treatment agent of hypertension complication effect.
Solution of the present invention is based on motherland's medical science to hypertension and pathogenetic understanding of complication and Therapeutic Principle, achieve with reference to modern pharmacological research, from motherland medicine treasure-house, filter out easing the affected liver and in, the natural plant of nourshing blood and promoting blood circulation, promoting the flow of QI-blood by warming the meridian, the lucid yang sending up sending down the abnormal ascending QI, by the theory of Chinese medical science prescription, make its performance vascular smooth muscle of releiving, the expansion peripheral blood vessel plays hypotensive effect, make heart contraction strong simultaneously, diastole fully and significantly.Increase brain and crown vascular flow, suppress atherosclerosis and superficial ulcer thereof, strengthen neural excitement and process of inhibition, promote the mutual balance of two kinds of nervous process, thereby performance reduced hypertension, particularly diastolic pressure, suppressed atherosclerosis and ulcer thereof, improve the cardiovascular and cerebrovascular vessel supply, reduce the effect of hypertension complication.
The present invention makes (consumption is a weight portion) by following component
10-25 parts of 20-80 parts of Ramulus Cinnamomi of the Radix Paeoniae Alba
10-20 parts of 5-25 parts of Radix Glycyrrhizae of Fructus Schisandrae Chinensis
10-30 parts of 5-25 parts of Radix Puerariaes of Radix Achyranthis Bidentatae
The formula optimization weight proportion scope of preparation medicine of the present invention is:
10-20 parts of 30-60 parts of Ramulus Cinnamomi of the Radix Paeoniae Alba
10-15 parts of 10-20 parts of Radix Glycyrrhizae of Fructus Schisandrae Chinensis
30-50 parts of 20-30 parts of Radix Puerariaes of Radix Achyranthis Bidentatae
Optimum weight proportioning of the present invention is:
15 parts of 15 parts of Fructus Schisandrae Chinensis of 60 parts of Ramulus Cinnamomi of the Radix Paeoniae Alba
40 parts of 30 parts of Radix Puerariaes of 10 parts of Radix Achyranthis Bidentataes of Radix Glycyrrhizae
Above-mentioned each component is made medicine production method of the present invention is:
1, gets above-mentioned component medicine, choose clean dried;
2, the medical material mixed powder is broken into 10-20 orders;
3, make in the filter paper bag that dosage (6g/ bag) splitting is packed ability boiling water into special and soaked in accordance with regulations and make tea.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, to select natural plant for use be raw material in the present invention, and each component meets the pharmaceutical control law regulation.Utilize the comprehensive function treatment hypertension of the Chinese medicine of respectively distinguishing the flavor of, nontoxic to human body.
2, the present invention need not decoct taking convenience.
3, I, II type hypertension can be used separately.Can unite use with other depressor than severe disease disease, but can shorten the control procedure of critical illness greatly, reduce the generation of various complication, resist other depressor toxic and side effects.
4, drug effect of the present invention is fast, but obtains decrement long-term drink after the produce effects, consolidates curative effect.
For showing the therapeutic effect of the present invention to hypertension, the inventor is divided into two groups at random with 60 routine hypertension (II phase) patient, adopt the treatment of the present invention and nimodipine tablet respectively, wherein, test group man 14 examples, 34-63 years old ages, 46.83 ± 1.94 years old mean age; Each 15 example of matched group men and women, 32-62 years old ages, average 45.96 ± 2.25 years old.Learn check by statistics, two groups of age differencess are not remarkable, P＞0.05.
Therapeutic Method: test group: the depressor of stopping using, obey medicine of the present invention, each one bag (6 gram), every day three times: matched group a: 40mg, three times on the one.10 days observe the curative effect of medication.Clinical test results is as table (1,2)
Table 1 is taken before and after medicine of the present invention, the nimodipine tablet
Diastolic pressure (Kpa) average relatively
| DBP average medication DBP P before the medication of example number | |
| Test group matched group P | ?30???????13.95±0.56??????11.05±0.35＜0.01 ?30???????14.01±0.75??????12.34±0.42＜0.05 ???????????＞0.05?????????????0.01＜P＜0.05 |
Table 2 is taken before and after medicine of the present invention, the nimodipine tablet
The systolic pressure average relatively
| SBP average P after the medication of SBP average before the medication | |
| Test group matched group P | ?23.47±0.75?????????18.29±0.44???＜0.05 ?23.56±0.72?????????17.48±0.39???＜0.05 ???＞0.05??????????????＞0.05 |
As can be seen from Table 1, diastolic pressure average difference is not remarkable before two groups of medications, P＞0.05, test group DBP average is lower than matched group after the medication, the two significant difference, 0.01＜P＜0.05 illustrates that medicine of the present invention is better than nimodipine tablet aspect the high diastolic blood pressure reducing.
Table 2 data show, SBP average no significant difference before and after two groups of medications, and P＞0.05 explanation the two difference aspect the too high systolic pressure of reduction is not remarkable.
The doing well,improving situation was contrasted before and after we also took medicine hypertension deflection headache patient, the results are shown in Table 3.
Table 3 is taken medicine of the present invention, nimodipine tablet
Treatment migraine effect relatively
| Healing number cure rate (%) before the treatment | |
| The test group matched group | ??18??????15(11.83)??????83.33 ??17??????8(11.17)???????47.05 |
| Add up to | ??35?????????23??????????65.71 |
X
2Check, two groups of cure rate significant differences, 0.01＜P＜0.05.
Table 3 data show that medicine of the present invention aspect the migraine, is better than nimodipine tablet due to the treatment hypertension.
Embodiment
Take by weighing raw material by following proportioning:
1.5 kilograms of 1.5 kilograms of Fructus Schisandrae Chinensis of 6 kilograms of Ramulus Cinnamomi of white peony root
1 kilogram in 4 kilograms of Radix Achyranthis Bidentataes of Radix Puerariae, 3 kilogram of raw Radix Glycyrrhizaes
Production method is as follows
After above-mentioned raw materials chosen clean dried, pulverizing medicinal materials is become the 10--32 order, mix homogeneously, by 6g/ packed go into to make in the filter paper that special anti-boiling water soaks make tea.
Claims (4)
1, a kind of medicine for the treatment of hypertension is characterized in that it is the medicament of being made by the following weight proportion raw material
10-25 parts of 20-80 parts of Ramulus Cinnamomi of the Radix Paeoniae Alba
10-25 parts of 5-25 parts of Radix Glycyrrhizae of Fructus Schisandrae Chinensis
10-50 parts of 10-40 parts of Radix Puerariaes of Radix Achyranthis Bidentatae
2, according to the medicine of right 1 described treatment hypertension, wherein the weight proportion of each raw material is
10 parts of 15 parts of Radix Glycyrrhizae of 15 parts of Fructus Schisandrae Chinensis of 60 parts of Ramulus Cinnamomi of the Radix Paeoniae Alba
40 parts of 30 parts of Radix Puerariaes of Radix Achyranthis Bidentatae
3,, it is characterized in that said medicament is a said dosage form on any pharmaceutics according to the medicine of right 1,2 described treatment hypertension.
4, the medicine of treatment hypertension according to claim 3 is characterized in that said medicament is a medicinal tea.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95103456 CN1115663A (en) | 1995-05-08 | 1995-05-08 | Medicine for curing hypertension |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95103456 CN1115663A (en) | 1995-05-08 | 1995-05-08 | Medicine for curing hypertension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1115663A true CN1115663A (en) | 1996-01-31 |
Family
ID=5074733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 95103456 Pending CN1115663A (en) | 1995-05-08 | 1995-05-08 | Medicine for curing hypertension |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1115663A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101822726A (en) * | 2010-03-09 | 2010-09-08 | 烟台大洋制药有限公司 | Medicine or healthcare food with liver protection function |
| CN102813746A (en) * | 2012-08-01 | 2012-12-12 | 河南科技大学 | Traditional Chinese medicine composition for treating numbness of fingers |
| CN103690834A (en) * | 2013-12-30 | 2014-04-02 | 广西梧州制药（集团）股份有限公司 | Antihypertensive traditional Chinese medicinal composition and preparation method thereof |
| CN109106891A (en) * | 2018-09-25 | 2019-01-01 | 安徽兆龙食品有限公司 | It is a kind of to absorb fast biological agent and preparation method thereof |
| CN112190668A (en) * | 2020-10-26 | 2021-01-08 | 焦作赛科中药生物科技有限公司 | Fermented traditional Chinese medicine tea assisting in lowering blood pressure and preparation method thereof |
-
1995
- 1995-05-08 CN CN 95103456 patent/CN1115663A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101822726A (en) * | 2010-03-09 | 2010-09-08 | 烟台大洋制药有限公司 | Medicine or healthcare food with liver protection function |
| CN101822726B (en) * | 2010-03-09 | 2011-08-24 | 烟台大洋制药有限公司 | Medicine or healthcare food with liver protection function |
| CN102813746A (en) * | 2012-08-01 | 2012-12-12 | 河南科技大学 | Traditional Chinese medicine composition for treating numbness of fingers |
| CN103690834A (en) * | 2013-12-30 | 2014-04-02 | 广西梧州制药（集团）股份有限公司 | Antihypertensive traditional Chinese medicinal composition and preparation method thereof |
| CN109106891A (en) * | 2018-09-25 | 2019-01-01 | 安徽兆龙食品有限公司 | It is a kind of to absorb fast biological agent and preparation method thereof |
| CN112190668A (en) * | 2020-10-26 | 2021-01-08 | 焦作赛科中药生物科技有限公司 | Fermented traditional Chinese medicine tea assisting in lowering blood pressure and preparation method thereof |
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